Lene Juel Rasmussen
Professor
- 2024
- Published
Cognitive Function Is Associated with the Genetically Determined Efficiency of DNA Repair Mechanisms
Cherbuin, N., Patel, H., Walsh, E. I., Ambikairajah, A., Burns, R., Brüstle, A. & Rasmussen, Lene Juel, 2024, In: Genes. 15, 2, 15 p., 153.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of reactive oxygen species and mitochondrial dysfunction on reproductive aging
Song, J., Xiao, L., Zhang, Z., Wang, Y., Kouis, P., Rasmussen, Lene Juel & Dai, F., 2024, In: Frontiers in Cell and Developmental Biology. 12, 12 p., 1347286.Research output: Contribution to journal › Review › Research › peer-review
- Published
Interactions between mitochondrial dysfunction and other hallmarks of aging: Paving a path toward interventions that promote healthy old age
Li, Yuan, Berliocchi, Laura, Li, Zhiquan & Rasmussen, Lene Juel, 2024, In: Aging Cell. 23, 1, 12 p., e13942.Research output: Contribution to journal › Review › Research › peer-review
- Published
Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway-UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies
Wang, H. L., Siow, R., Schmauck-Medina, T., Zhang, J., Sandset, P. M., Filshie, C., Lund, Ø., Partridge, L., Bergersen, L. H., Juel Rasmussen, L., Palikaras, K., Sotiropoulos, I., Storm-Mathisen, J., Rubinsztein, D. C., Spillantini, M. G., De Zeeuw, C. I., Watne, L. O., Vyhnalek, M., Veverova, K., Liang, K. X. & 18 others, , 2024, In: The journals of gerontology. Series A, Biological sciences and medical sciences. 79, 4, 10 p., glae029.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Salidroside promotes healthy longevity by interfering with HSP90 activity
Zhang, J., Li, Zhiquan, Song, J., Zhou, L., Chen, X., Ge, W., Dong, T., Luo, Y., Mao, T., Li, Z., Tan, D., Rasmussen, Lene Juel, Bohr, Vilhelm, Tong, X. & Dai, F., 2024, In: GeroScience. 46, p. 1641–1655 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The cGAS-STING signaling pathway is modulated by urolithin A
Madsen, Helena Borland, Park, J. H., Chu, X., Hou, Y., Li, Zhiquan, Rasmussen, Lene Juel, Croteau, D. L., Bohr, Vilhelm & Akbari, M., 2024, In: Mechanisms of Ageing and Development. 217, 11 p., 111897.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Rev1 deficiency induces a metabolic shift in MEFs that can be manipulated by the NAD+ precursor nicotinamide riboside
Anugula, Sharath, Li, Zhiquan, Li, Yuan, Hendriksen, A., Christensen, P. B., Wang, L., Monk, J. M., de Wind, N., Bohr, Vilhelm, Desler, Claus, Naviaux, R. K. & Rasmussen, Lene Juel, 2023, In: Heliyon. 9, 6, e17392.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detecting user experience issues from mHealth apps that support stroke caregiver needs: an analysis of user reviews
Lobo, E. H., Abdelrazek, M., Frølich, Anne, Rasmussen, Lene Juel, Livingston, P. M., Islam, S. M. S., Kensing, Finn & Grundy, J., 2023, In: Frontiers in Public Health. 11, 9 p., 1027667.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Galectin-7 reprograms skin carcinogenesis by fostering innate immune evasive programs
Pinto, N. A., Abba, M. C., Laporte, L., Pérez Sáez, J. M., Blidner, A. G., Torres, N. I., Morales, R. M., Gatto, S. G., Bach, C. A., Veigas, F., García Rivello, H. J., Song, P., Frederiksen, J. H., Rasmussen, Lene Juel, Poirier, F., Croci, D. O., Sundblad, V., Rabinovich, G. A. & Cerliani, J. P., 2023, In: Cell Death and Differentiation. 30, p. pages906–921Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Information, involvement, self-care and support—The needs of caregivers of people with stroke: A grounded theory approach
Lobo, E. H., Frølich, Anne, Abdelrazek, M., Rasmussen, Lene Juel, Grundy, J., Livingston, P. M., Islam, S. M. S. & Kensing, Finn, 2023, In: PLoS ONE. 18, 1, p. 1-25 25 p., e0281198.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MRE11A: a novel negative regulator of human DNA mismatch repair
Du, D., Yang, Y., Wang, G., Chen, L., Guan, X., Rasmussen, Lene Juel & Liu, D., 2023, bioRxiv, 34 p.Research output: Working paper › Preprint › Research
- Published
Pooled analysis of frontal lobe transcriptomic data identifies key mitophagy gene changes in Alzheimer's disease brain
Mei, T., Li, Yuan, Orduña Dolado, A., Li, Zhiquan, Andersson, Robin, Berliocchi, Laura & Rasmussen, Lene Juel, 2023, In: Frontiers in Aging Neuroscience. 15, 14 p., 1101216.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The DNA repair enzyme, aprataxin, plays a role in innate immune signaling
Madsen, Helena Borland, Pease, L. I., Scanlan, R. L., Akbari, M., Rasmussen, Lene Juel, Shanley, D. P. & Bohr, Vilhelm, 2023, In: Frontiers in Aging Neuroscience. 15, 17 p., 1290681.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
CNOT6: A Novel Regulator of DNA Mismatch Repair
Song, P., Liu, S., Liu, D., Keijzers, G., Bakula, Daniela Janina, Duan, S., de Wind, N., Ye, Z., Vakhrushev, Sergey, Scheibye-Knudsen, Morten & Rasmussen, Lene Juel, 2022, In: Cells. 11, 3, 521.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium
The European Hereditary Tumour Group (EHTG) and the International Mismatch Repair Consortium (IMRC), T. E. H. T. G. (. A. T. I. M. R. C. (., 2022, In: Hereditary Cancer in Clinical Practice. 20, 36.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic instability and aging
Li, Zhiquan, Anugula, Sharath & Rasmussen, Lene Juel, 2022, Aging: From Fundamental Biology to Societal Impact. Oliveira, P. J. & Malva, J. O. (eds.). Academic Press, p. 275-295 21 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary
Schmauck-Medina, T., Molière, A., Lautrup, S., Zhang, J., Chlopicki, S., Madsen, H. B., Cao, S., Soendenbroe, C., Mansell, E., Vestergaard, M. B., Li, Z., Shiloh, Y., Opresko, P. L., Egly, J. M., Kirkwood, T., Verdin, E., Bohr, V. A., Cox, L. S., Stevnsner, T., Rasmussen, L. J. & 1 others, , 2022, In: Aging. 14, 16, p. 6829-6839 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Partial inhibition of mitochondrial-linked pyrimidine synthesis increases tumorigenic potential and lysosome accumulation
Desler, Claus, Durhuus, J. A., Hansen, T. L. L., Anugula, Sharath, Zelander, N. T., Bøggild, S. & Rasmussen, Lene Juel, 2022, In: Mitochondrion. 64, p. 73-81 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RANKL regulates testicular cancer growth and Denosumab treatment has suppressive effects on GCNIS and advanced seminoma
Andreassen, C. H., Lorenzen, M., Nielsen, J. E., Kafai Yahyavi, S., Toft, Birgitte Grønkær, Ingerslev, L. R., Clemmensen, Christoffer, Rasmussen, Lene Juel, Bokemeyer, C., Juul, Anders, Jørgensen, A. & Jensen, M. B., 2022, In: British Journal of Cancer. 127, p. 408-421Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systems modelling predicts chronic inflammation and genomic instability prevent effective mitochondrial regulation during biological ageing
Guimera, A. M., Clark, P., Wordsworth, J., Anugula, Sharath, Rasmussen, Lene Juel & Shanley, D. P., 2022, In: Experimental Gerontology. 166, 9 p., 111889.Research output: Contribution to journal › Review › Research › peer-review
- Published
Technology-based support for stroke caregiving: A rapid review of evidence
Lobo, E. H., Abdelrazek, M., Kensing, Finn, Rasmussen, Lene Juel, Livingston, P. M., Grundy, J., Islam, S. M. S. & Frølich, Anne, 2022, In: Journal of Nursing Management. 30, 8, p. 3700-3713 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Utilization of social media communities for caregiver information support in stroke recovery: An analysis of content and interactions
Lobo, E. H., Johnson, T., Frølich, Anne, Kensing, Finn, Rasmussen, Lene Juel, Hosking, S. M., Page, A. T., Livingston, P. M., Islam, S. M. S., Grundy, J. & Abdelrazek, M., 2022, In: PLoS ONE. 17, 1, 19 p., e0262919.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
mHealth intervention for carers of individuals with a history of stroke: Heuristic evaluation and user perspectives
Lobo, E. H., Kensing, Finn, Frølich, Anne, Rasmussen, Lene Juel, Livingston, P. M., Islam, S. M. S., Grundy, J. & Abdelrazek, M., 2022, In: Digital Health. 8, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study
The International Mismatch Repair Consortium, T. I. M. R. C., Jul 2021, In: The Lancet Oncology. 22, 7, p. 1014-1022 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Societal need for interdisciplinary ageing research
Cherbuin, N., Lijima, K., Kalula, S., Malhotrad, R., Rasmussen, Lene Juel, Chan, A., Lafortune, L., Harper, S., Zheng, X., Lindeman, D., Walsh, E., Hussain, R., Burns, R., Kristiansen, Maria, Sugawara, I., Son, B., Tanaka, T., Buckner, S., Hoffman, J. & Combrinck, M., 25 Feb 2021, In: Biomedicine Hub. 6, 1, p. 42-47 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bloom syndrome DNA helicase deficiency is associated with oxidative stress and mitochondrial network changes
Subramanian, V., Rodemoyer, B., Shastri, V., Rasmussen, Lene Juel, Desler, Claus & Schmidt, K. H., 2021, In: Scientific Reports. 11, 2157.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Caregiver Engagement in Stroke Care: Opportunities and Challenges in Australia and Denmark
Lobo, E. H. S., Abdelrazek, M., Grundy, J., Kensing, F., Livingston, P. M., Rasmussen, Lene Juel, Islam, S. M. S. & Frølich, Anne, 2021, In: Frontiers in Public Health. 9, 6 p., 758808.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cytosolic self-DNA—A potential source of chronic inflammation in aging
Akbari, M., Shanley, D. P., Bohr, Vilhelm & Rasmussen, Lene Juel, 2021, In: Cells. 10, 12, 3544.Research output: Contribution to journal › Review › Research › peer-review
- Published
EX-vivo whole blood stimulation with A2E does not elicit an inflammatory cytokine response in patients with age-related macular degeneration
Durhuus, J. A., Rozing, Maarten Pieter, Nielsen, M. K., Molbech, C. R., Keijzers, G., Scheibye-Knudsen, Morten, Rasmussen, Lene Juel, Westendorp, Rudi GJ & Sørensen, Torben Lykke, 2021, In: Scientific Reports. 11, 1, 8226.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial-Linked De Novo Pyrimidine Biosynthesis Dictates Human T-Cell Proliferation but Not Expression of Effector Molecules
Peeters, M. J. W., Aehnlich, P., Pizzella, A., Mølgaard, K., Seremet, T., Met, Özcan, Rasmussen, Lene Juel, thor Straten, P. & Desler, Claus, 2021, In: Frontiers in Immunology. 12, 718863.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Understanding the Methodological Issues and Solutions in the Research Design of Stroke Caregiving Technology
Lobo, E. H., Frølich, Anne, Rasmussen, Lene Juel, Livingston, P. M., Grundy, J., Abdelrazek, M. & Kensing, Finn, 2021, In: Frontiers in Public Health. 9, 7 p., 647249.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
mHealth applications to support caregiver needs and engagement during stroke recovery: A content review
Lobo, E. H., Frølich, Anne, Kensing, Finn, Rasmussen, Lene Juel, Livingston, P. M., Grundy, J. & Abdelrazek, M., 2021, In: Research in Nursing and Health. 44, 1, p. 213-225Research output: Contribution to journal › Review › Research › peer-review
- 2020
- Published
ARDD 2020: from aging mechanisms to interventions
Mkrtchyan, G. V., Abdelmohsen, K., Andreux, P., Bagdonaite, I., Barzilai, N., Brunak, S., Cabreiro, F., Cabo, R. D., Campisi, J., Cuervo, A. M., Demaria, M., Ewald, C. Y., Fang, E. F., Faragher, R., Ferrucci, L., Freund, A., Silva-García, C. G., Georgievskaya, A., Gladyshev, V. N., Glass, D. J. & 46 others, , 2020, In: Aging. 12, 24, p. 24486-24503 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells
Møller, S. H., Mellergaard, M., Madsen, M., Bermejo, A. V., Jepsen, Stine Dam, Hansen, M. H., Høgh, R. I., Aldana, Blanca, Desler, Claus, Rasmussen, Lene Juel, Sustarsic, E. G., Gerhart-Hines, Zach, Daskalaki, E., Wheelock, C. E., Hiron, T. K., Lin, D., O'Callaghan, C. A., Wandall, Hans H., Andresen, Lars & Skov, Søren, 2020, In: Frontiers in Immunology. 11, 22 p., 1968.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of Nodal signalling on pluripotency factor expression, tumour cell proliferation and cisplatin-sensitivity in testicular germ cell tumours
Harpelunde Poulsen, K., Nielsen, J. E., Grønkær Toft, B., Joensen, Ulla Nordström, Rasmussen, Lene Juel, Blomberg Jensen, M., Mitchell, R. T., Juul, Anders, Rajpert-De Meyts, E. & Jørgensen, Anders, 2020, In: BMC Cancer. 20, 1, 14 p., 349.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction between RECQL4 and OGG1 promotes repair of oxidative base lesion 8-oxoG and is regulated by SIRT1 deacetylase
Duan, S., Han, X., Akbari, M., Croteau, D. L., Rasmussen, Lene Juel & Bohr, Vilhelm, 2020, In: Nucleic Acids Research. 48, 12, p. 6530–6546Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial Function in Gilles de la Tourette Syndrome Patients With and Without Intragenic IMMP2L Deletions
Bjerregaard, Victoria Alexandra, Schönewolf-Greulich, B., Rasmussen, Lene Juel, Desler, Claus & Tümer, Asuman Zeynep, 2020, In: Frontiers in Neurology. 11, 9 p., 163.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial dysfunction induced by variation in the non-coding genome – A proposed workflow to improve diagnostics
du Mee, D. J. M., Bak, M., Østergaard, Elsebet & Rasmussen, Lene Juel, 2020, In: Mitochondrion. 53, p. 255-259Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simvastatin improves mitochondrial respiration in peripheral blood cells
Durhuus, J. A., Hansson, Svenja, Morville, T., Kuhlman, A. B., Dohlmann, T. L., Larsen, Steen, Helge, Jørn Wulff, Angleys, M., Muniesa-Vargas, A., Bundgaard, J. R., Hickson, Ian David, Dela, Flemming, Desler, Claus & Rasmussen, Lene Juel, 2020, In: Scientific Reports. 10, 1, 17012.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease
Navarro, J. F., Croteau, D. L., Jurek, A., Andrusivova, Z., Yang, B., Wang, Y., Ogedegbe, B., Riaz, T., Støen, M., Desler, Claus, Rasmussen, Lene Juel, Tønjum, T., Galas, M. C., Lundeberg, J. & Bohr, Vilhelm, 2020, In: iScience. 23, 10, 42 p., 101556.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TIP60 in aging and neurodegeneration
Li, Zhiquan & Rasmussen, Lene Juel, 2020, In: Ageing Research Reviews. 64, 101195.Research output: Contribution to journal › Review › Research › peer-review
- Published
The NAD+-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications
Aman, Y., Frank, J., Lautrup, S. H., Matysek, A., Niu, Z., Yang, G., Shi, L., Bergersen, L. H., Storm-Mathisen, J., Rasmussen, Lene Juel, Bohr, Vilhelm, Nilsen, H. & Fang, E. F., 2020, In: Mechanisms of Ageing and Development. 185, 111194.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two integrated and highly predictive functional analysis-based procedures for the classification of MSH6 variants in Lynch syndrome
Drost, M., Tiersma, Y., Glubb, D., Kathe, S., van Hees, S., Calléja, F., Zonneveld, J. B. M., Boucher, K. M., Ramlal, R. P. E., Thompson, B. A., Rasmussen, Lene Juel, Greenblatt, M. S., Lee, A., Spurdle, A. B., Tavtigian, S. V. & de Wind, N., 2020, In: Genetics in Medicine. 22, p. 847–856Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
A Ketogenic Diet Improves Mitochondrial Biogenesis and Bioenergetics via the PGC1α-SIRT3-UCP2 Axis
Hasan-Olive, M. M., Lauritzen, K. H., Ali, M., Rasmussen, Lene Juel, Storm-Mathisen, J. & Bergersen, L. H., 2019, In: Neurochemical Research. 44, 1, p. 22-37 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A functional assay–based procedure to classify mismatch repair gene variants in Lynch syndrome
Drost, M., Tiersma, Y., Thompson, B. A., Frederiksen, J. H., Keijzers, G., Glubb, D., Kathe, S., Osinga, J., Westers, H., Pappas, L., Boucher, K. M., Molenkamp, S., Zonneveld, J. B., van Asperen, C. J., Goldgar, D. E., Wallace, S. S., Sijmons, R. H., Spurdle, A. B., Rasmussen, L. J., Greenblatt, M. S. & 2 others, , 2019, In: Genetics in Medicine. 21, p. 1486–1496Research output: Contribution to journal › Journal article › Research › peer-review
- Published
From powerhouse to perpetrator—mitochondria in health and disease
Fakouri, N. B., Hansen, T. L., Desler, Claus, Anugula, Sharath & Rasmussen, Lene Juel, 2019, In: Biology. 8, 2, 15 p., 35.Research output: Contribution to journal › Review › Research › peer-review
- Published
MERTK Acts as a costimulatory receptor on human cd8 t cells
Peeters, M. J. W., Dulkeviciute, D., Draghi, A., Ritter, C., Rahbech, A., Skadborg, S. K., Seremet, T., Simoes, A. M. C., Martinenaite, E., Halldorsdottir, H. R., Andersen, Mads Hald, Olofsson, G. H., Svane, Inge Marie, Rasmussen, Lene Juel, Met, Özcan, Becker, J. C., dqp123, dqp123, Desler, Claus & Straten, P. T., 2019, In: Cancer Immunology Research. 7, 9, p. 1472-1484 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial oxidative phosphorylation capacity of cryopreserved cells
Lauridsen, P. E., Rasmussen, Lene Juel & Desler, Claus, 2019, In: Mitochondrion. 47, p. 47-53 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Turtles maintain mitochondrial integrity but reduce mitochondrial respiratory capacity in the heart after cold acclimation and anoxia
Bundgaard, A., Qvortrup, Klaus, Rasmussen, Lene Juel & Fago, A., 2019, In: Journal of Experimental Biology. 222, 11, 9 p., jeb200410.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Initial brain aging: heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus
Thomsen, Kirsten Joan, Yokota, T., Hasan-Olive, M. M., Sherazi, N., Fakouri, N. B., Desler, Claus, Regnell, C. E., Larsen, S., Rasmussen, Lene Juel, Dela, Flemming, Bergersen, L. H. & Lauritzen, Martin, 2018, In: Neurobiology of Aging. 61, p. 215-224 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The inhibitors of soluble adenylate cyclase 2-OHE, KH7, and bithionol compromise mitochondrial ATP production by distinct mechanisms
Jakobsen, Emil, Lange, S. C., Andersen, Jens Velde, Desler, Claus, Kihl, H. F., Hohnholt, M., Stridh, M. H., Rasmussen, Lene Juel, Waagepetersen, Helle S. & Bak, Lasse Kristoffer, 2018, In: Biochemical Pharmacology. 155, p. 92-101 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of mitochondrial dysfunction in the progression of Alzheimer’s disease
Desler, Claus, Lillenes, M. S., Tønjum, T. & Rasmussen, Lene Juel, 2018, In: Current Medicinal Chemistry. 25, 40, p. 5578 - 5587Research output: Contribution to journal › Review › Research › peer-review
- 2017
- Published
Bacterial infection increases risk of carcinogenesis by targeting mitochondria
Strickertsson, J. A. B., Desler, Claus & Rasmussen, Lene Juel, Dec 2017, In: Seminars in Cancer Biology. 47, p. 95-100 6 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Human DNA polymerase delta double-mutant D316A;E318A interferes with DNA mismatch repair in vitro
Liu, D., Frederiksen, J. H., Liberti, S. E., Lützen, Anne Hoff Kjeldsen, Keijzers, G., Pena-Diaz, J. & Rasmussen, Lene Juel, 19 Sep 2017, In: Nucleic Acids Research. 45, 16, p. 9427-9440 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA mismatch repair and its many roles in eukaryotic cells
Liu, D., Keijzers, G. & Rasmussen, Lene Juel, Jul 2017, In: Mutation Research - Reviews in Mutation Research. 773, p. 174-187 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations
Nielsen, S. V., Stein, Amelie, Dinitzen, A. B., Papaleo, E., Tatham, M. H., Poulsen, E. G., Kassem, M. M., Rasmussen, Lene Juel, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 19 Apr 2017, In: PLoS Genetics. 13, 4, 26 p., e1006739.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nanomaterial-induced cell death in pulmonary and hepatic cells following exposure to three different metallic materials: The role of autophagy and apoptosis
Kermanizadeh, A., Jantzen, K., Ward, M. B., Durhuus, J. A., Rasmussen, Lene Juel, Loft, Steffen & Møller, Peter, Mar 2017, In: Nanotoxicology. 11, 2, p. 184-200 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
EXO1 (Exonuclease 1)
Rasmussen, Lene Juel & Keijzers, G., 5 Jan 2017, Encyclopedia of Signaling Molecules . Choi, S. (ed.). New York: Springer, 7 p.Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Research
- Published
Bioenergetic Changes during Differentiation of Human Embryonic Stem Cells along the Hepatic Lineage
Hopkinson, B. M., Desler, Claus, Kalisz, M., Vestentoft, P. S., Rasmussen, Lene Juel & Bisgaard, Hanne Cathrine, 2017, In: Oxidative Medicine and Cellular Longevity. 2017, 11 p., 5080128.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disturbed mitochondrial function restricts glutamate uptake in the human Müller glia cell line, MIO-M1
Vohra, Rupali, Gurubaran, I. S., Henriksen, U., Bergersen, L. H., Rasmussen, Lene Juel, Desler, C., Jensen, Dorte Skytt & Kolko, Miriam, 2017, In: Mitochondrion. 36, p. 52-59Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions
Martín-Pardillos, A., Tsaalbi-Shtylik, A., Chen, S., Lazare, S., Van Os, R. P., Dethmers-Ausema, A., Fakouri, N. B., Bosshard, M., Aprigliano, R., Van Loon, B., Salvatori, D. C. F., Hashimoto, K., Van Der Spek, C. D., Moriya, M., Rasmussen, Lene Juel, De Haan, G., Raaijmakers, M. H. G. P. & De Wind, N., 2017, In: Blood. 130, 13, p. 1523-1534 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Involvement of the DNA mismatch repair system in cisplatin sensitivity of testicular germ cell tumours
Rudolph, C., Melau, C., Nielsen, J. E., Jensen, K. V., Liu, D., Pena-Diaz, J., Meyts, E. R., Rasmussen, Lene Juel & Jorgensen, A., 2017, In: Cellular Oncology. 40, 4, p. 341-355Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1 alpha axis
Fakouri, N. B., Durhuus, J. A., Regnell, C. E., Angleys, M., Desler, Claus, Hasan-Olive, M., Martin-Pardillos, A., Tsaalbi-Shtylik, A., Thomsen, Kirsten Joan, Lauritzen, Martin, Bohr, Vilhelm, de Wind, N., Bergersen, L. H. & Rasmussen, Lene Juel, 2017, In: Scientific Reports. 7, 14 p., 12480.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
A Novel Rrm3 Function in Restricting DNA Replication via an Orc5-Binding Domain Is Genetically Separable from Rrm3 Function as an ATPase/Helicase in Facilitating Fork Progression
Syed, S., Desler, Claus, Rasmussen, Lene Juel & Schmidt, K. H., Dec 2016, In: P L o S Genetics. 12, 12, 28 p., e1006451.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interventions for age-related diseases: Shifting the paradigm
Figueira, I., Fernandes, A., Mladenovic Djordjevic, A., Lopez-Contreras, Andres, Henriques, C. M., Selman, C., Ferreiro, E., Gonos, E. S., Trejo, J. L., Misra, J., Rasmussen, Lene Juel, Xapelli, S., Ellam, T. & Bellantuono, I., Dec 2016, In: Mechanisms of Ageing and Development. 160, p. 69-92 24 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Exonuclease 1 and its versatile roles in DNA repair
Keijzers, G., Liu, D. & Rasmussen, Lene Juel, 5 Aug 2016, In: Critical Reviews in Biochemistry and Molecular Biology. 51, 6, p. 440–451 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks
Lu, H., Shamanna, R. A., Keijzers, G., Anand, R., Rasmussen, Lene Juel, Cejka, P., Croteau, D. L. & Bohr, Vilhelm, 28 Jun 2016, In: Cell Reports. 16, 1, p. 161-173 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acquired Localized Cutis Laxa due to Increased Elastin Turnover
Nygaard, R. H., Maynard, S., Schjerling, P., Kjær, M., Qvortrup, Klaus, Bohr, Vilhelm, Rasmussen, Lene Juel, Jemec, Gregor & Heidenheim, M., 14 Jun 2016, In: Case Reports in Dermatology. 8, 1, p. 42-51 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxidative Stress-Induced Dysfunction of Muller Cells During Starvation
Toft-Kehler, A. K., Gurubaran, I. S., Desler, Claus, Rasmussen, Lene Juel, Jensen, Dorte Skytt & Kolko, Miriam, May 2016, In: Investigative Ophthalmology & Visual Science. 57, 6, p. 2721-2728Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Approaches to diagnose DNA mismatch repair gene defects in cancer
Peña-Diaz, J. & Rasmussen, Lene Juel, Feb 2016, In: DNA Repair. 38, p. 147-154 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
LIFESTAT – Living with statins: An interdisciplinary project on the use of statins as a cholesterol-lowering treatment and for cardiovascular risk reduction
Christensen, Christa Lykke, Helge, Jørn Wulff, Krasnik, Allan, Kriegbaum, Margit, Rasmussen, Lene Juel, Hickson, Ian David, Liisberg, Kasper Bering, Oxlund, Bjarke, Bruun, B., Lau, Sofie Rosenlund, Olsen, M. N. A., Andersen, John Sahl, Heltberg, Andreas Søndergaard, Kuhlman, A. C. B., Morville, T. H., Dohlmann, T. L., Larsen, Steen & Dela, Flemming, 2016, In: Scandinavian Journal of Public Health. 44, 5, p. 534-539 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Increased deoxythymidine triphosphate levels is a feature of relative cognitive decline
Desler, Claus, Frederiksen, J. H., Olsen, M. N. A., Maynard, S., Keijzers, G., Fagerlund, Birgitte, Mortensen, Erik Lykke, Osler, Merete, Lauritzen, Martin, Bohr, Vilhelm & Rasmussen, Lene Juel, Nov 2015, In: Mitochondrion. 25, p. 34-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Defective mitochondrial respiration, altered dNTP pools and reduced AP endonuclease 1 activity in peripheral blood mononuclear cells of Alzheimer's disease patients
Maynard, S., Hejl, Anne-Mette, Dinh, T. T. S., Keijzers, G., Hansen, Åse Marie, Desler, Claus, Moreno-Villanueva, M., Bürkle, A., Rasmussen, Lene Juel, Waldemar, Gunhild & Bohr, Vilhelm, Oct 2015, In: Aging. 7, 10, p. 793-815 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure
Lauritzen, K. H., Kleppa, L., Aronsen, J. M., Eide, L., Carlsen, H., Haugen, O. P., Sjaastad, I., Klungland, A., Rasmussen, Lene Juel, Attramadal, H., Storm-Mathisen, J. & Bergersen, L. H., 1 Aug 2015, In: American Journal of Physiology: Heart and Circulatory Physiology. 309, 3, p. H434-H449 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice
Lopez-Contreras, Andres, Specks, J., Barlow, J. H., Ambrogio, C., Desler, Claus, Vikingsson, S., Rodrigo-Perez, S., Green, H., Rasmussen, Lene Juel, Murga, M., Nussenzweig, A. & Fernandez-Capetillo, O., 1 Apr 2015, In: Genes & Development. 29, 7, p. 690-5 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The challenges of human population ageing
Sander, M., Oxlund, Bjarke, Jespersen, Astrid Pernille, Krasnik, Allan, Mortensen, Erik Lykke, Westendorp, Rudi GJ & Rasmussen, Lene Juel, Mar 2015, In: Age and Ageing. 44, 2, p. 185-7 3 p.Research output: Contribution to journal › Journal article › Communication
- Published
Associations of subjective vitality with DNA damage, cardiovascular risk factors and physical performance
Maynard, S., Keijzers, G., Hansen, Åse Marie, Osler, Merete, Molbo, Drude, Bendix, L., Møller, Peter, Loft, Steffen, Moreno-Villanueva, M., Bürkle, A., Hvitby, C. P., Schurman, S. H., Stevnsner, T. V., Rasmussen, Lene Juel, Avlund, K. & Bohr, Vilhelm, Jan 2015, In: Acta Physiologica (Print). 213, 1, p. 156-170 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondria in health and disease: 3rd annual conference of society for mitochondrial research and medicine - 19-20 december 2013 - bengaluru, India
Durhuus, J. A., Desler, Claus & Rasmussen, Lene Juel, Jan 2015, In: Mitochondrion. 20, p. 7-12 6 p.Research output: Contribution to journal › Conference article › Research › peer-review
- Published
Human exonuclease 1 (EXO1) activity characterization and its function on FLAP structures
Keijzers, G., Bohr, Vilhelm & Rasmussen, Lene Juel, 2015, In: Bioscience Reports. 35, 3, 13 p., e00206.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Dynamics of the DNA repair proteins WRN and BLM in the nucleoplasm and nucleoli
Bendtsen, K. M., Jensen, M. B., May, A., Rasmussen, Lene Juel, Trusina, Ala, Bohr, Vilhelm & Jensen, Mogens Høgh, 14 Nov 2014, In: European Biophysics Journal. 43, 10-11, p. 509-516Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of RecQ helicases in non-homologous end-joining
Keijzers, G., Maynard, S., Shamanna, R. A., Rasmussen, Lene Juel, Croteau, D. L. & Bohr, Vilhelm, Nov 2014, In: Critical Reviews in Biochemistry and Molecular Biology. 49, 6, p. 463-472 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Enterococcus faecalis Infection and Reactive Oxygen Species Down-Regulates the miR-17-92 Cluster in Gastric Adenocarcinoma Cell Culture
Strickertsson, J. A. B., Rasmussen, Lene Juel & Friis-Hansen, Lennart Jan, 28 Aug 2014, In: Genes. 5, 3, p. 726-38 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of bacterial infections on aging and cancer: Impairment of DNA repair and mitochondrial function of host cells
Strickertsson, J. A. B., Desler, Claus & Rasmussen, Lene Juel, Aug 2014, In: Experimental Gerontology. 56, p. 164-174 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional implications of the p.Cys680Arg mutation in the MLH1 mismatch repair protein
Dominguez-Valentin, M., Drost, M., Therkildsen, C., Rambech, E., Ehrencrona, H., Angleys, M., Lau Hansen, T., de Wind, N., Nilbert, Mef Christina & Rasmussen, Lene Juel, Jul 2014, In: Molecular Genetics & Genomic Medicine. 2, 4, p. 352-355 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondria in biology and medicine--2012
Desler, Claus & Rasmussen, Lene Juel, May 2014, In: Mitochondrion. 16, p. 2-6 5 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Assessing Genetic Variants of Uncertain Significance: The Example of Lynch Syndrome
Rasmussen, Lene Juel & Heinen, C. D., 15 Apr 2014Research output: Other contribution › Net publication - Internet publication › Communication
- Published
Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database
Thompson, B. A., Spurdle, A. B., Plazzer, J-P., Greenblatt, M. S., Akagi, K., Al-Mulla, F., Bapat, B., Bernstein, I., Capellá, G., den Dunnen, J. T., du Sart, D., Fabre, A., Farrell, M. P., Farrington, S. M., Frayling, I. M., Frebourg, T., Goldgar, D. E., Heinen, C. D., Holinski-Feder, E., Kohonen-Corish, M. & 31 others, , Feb 2014, In: Nature Genetics. 46, 2, p. 107-115 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Introducing the hypothome: a way to integrate predicted proteins in interactomes
Desler, Claus, Zambach, S., Suravajhala, P. & Rasmussen, Lene Juel, 2014, In: International Journal of Bioinformatics Research and Applications. 10, 6, p. 647-52 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Relationships between human vitality and mitochondrial respiratory parameters, reactive oxygen species production and dNTP levels in peripheral blood mononuclear cells
Maynard, S., Keijzers, G., Gram, M., Desler, Claus, Bendix, L., Budtz-Joergensen, Esben, Molbo, Drude, Croteau, D. L., Osler, Merete, Stevnsner, T. V., Rasmussen, Lene Juel, Dela, Flemming, Avlund, K. & Bohr, Vilhelm, 30 Nov 2013, In: Aging. p. 850-864 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA damage response, bioenergetics, and neurological disease: the challenge of maintaining brain health in an aging human population
Rasmussen, Lene Juel, Shiloh, Y., Bergersen, L. H., Sander, M., Bohr, Vilhelm & Tønjum, T., Oct 2013, In: Mechanisms of Ageing and Development. 134, 10, p. 427-33 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic screens to identify pathogenic gene variants in the common cancer predisposition Lynch syndrome
Drost, M., Lützen, A., van Hees, S., Ferreira, D., Calléja, F., Zonneveld, J. B. M., Nielsen, Finn Cilius, Rasmussen, Lene Juel & de Wind, N., 4 Jun 2013, In: Proceedings of the National Academy of Science of the United States of America. 110, 23, p. 9403-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Response to: Design of a core classification process for DNA mismatch repair variations of a priori unknown functional significance
Rasmussen, Lene Juel, Heinen, C. D., Royer-Pokora, B., Drost, M., Tavtigian, S., Hofstra, R. M. W. & de Wind, N., Jun 2013, In: Human Mutation. 34, 6, p. 923-4 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Helicobacter pylori infection affects mitochondrial function and DNA repair, thus, mediating genetic instability in gastric cells
Machado, A. M. D., Desler, C., Boggild, S., Strickertsson, J. A. B., Friis-Hansen, Lennart Jan, Figueiredo, C., Seruca, R. & Rasmussen, Lene Juel, 2013, In: Mechanisms of Ageing and Development. 134, 10, p. 460-466 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enterococcus faecalis infection causes inflammation, intracellular oxphos-independent ROS production, and DNA damage in human gastric cancer cells
Strickertsson, J. A. B., Desler, Claus, Martin-Bertelsen, T., Machado, A. M. D., Wadstrøm, T., Winther, Ole, Rasmussen, Lene Juel & Friis-Hansen, Lennart Jan, 2013, In: PLOS ONE. 8, 4, p. 1-13 13 p., e63147.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional examination of MLH1, MSH2, and MSH6 intronic mutations identified in Danish colorectal cancer patients
Petersen, S. M., Dandanell, M., Rasmussen, Lene Juel, Gerdes, Anne-Marie Axø, Krogh, L. N., Bernstein, I., Okkels, H., Wikman, F., Nielsen, Finn Cilius & Hansen, Thomas van Overeem, 2013, In: BMC Medical Genetics. 14, p. 103Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic screens to identify pathogenic gene variants in the common cancer predisposition Lynch syndrome
Drost, M., Lützen, A., van Hees, S., Ferreira, D., Calléja, F., Zonneveld, J. B. M., Nielsen, Finn Cilius, Rasmussen, Lene Juel & de Wind, N., 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 23, p. 9403-9408 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Natural selection of mitochondria during somatic lifetime promotes healthy aging
Rodell, A., Rasmussen, Lene Juel, Bergersen, L. H., Singh, K. K. & Gjedde, Albert, 2013, In: Frontiers in Neuroenergetics. 5, p. 1-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Functional characterization of MLH1 missense variants identified in Lynch Syndrome patients
Andersen, S. D., Liberti, S. E., Lützen, A., Drost, M., Bernstein, I., Nilbert, Mef Christina, Dominguez, M., Nyström, M., Hansen, Thomas van Overeem, Christoffersen, J. W., Jäger, A. C., de Wind, N., Nielsen, Finn Cilius, Tørring, P. M. & Rasmussen, Lene Juel, Dec 2012, In: Human Mutation. 33, 12, p. 1647-1655 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pathological assessment of mismatch repair gene variants in Lynch syndrome: Past, present, and future
Rasmussen, Lene Juel, Heinen, C. D., Royer-Pokora, B., Drost, M., Tavtigian, S., Hofstra, R. M. W. & de Wind, N., Dec 2012, In: Human Mutation. 33, 12, p. 1617-25 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxidative damage to DNA by diesel exhaust particle exposure in co-cultures of human lung epithelial cells and macrophages
Jantzen, K., Roursgaard, Martin, Desler, Claus, Loft, Steffen, Rasmussen, Lene Juel & Møller, Peter, Nov 2012, In: Mutagenesis. 27, 6, p. 693-701 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The helicase and ATPase activities of RECQL4 are compromised by mutations reported in three human patients
Jensen, M. B., Dunn, C. A., Keijzers, G., Kulikowicz, T., Rasmussen, Lene Juel, Croteau, D. L. & Bohr, Vilhelm, Nov 2012, In: Aging. 4, 11, p. 790-802 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determining the functional significance of mismatch repair gene missense variants using biochemical and cellular assays
Heinen, C. D. & Rasmussen, Lene Juel, Jul 2012, In: Hereditary Cancer in Clinical Practice. 10, 1, p. 9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondria in biology and medicine
Desler, Claus & Rasmussen, Lene Juel, Jul 2012, In: Mitochondrion. 12, 4, p. 472-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Alterations of monocarboxylate transporter densities during hypoxia in brain and breast tumour cells
Cheng, C., Edin, N. F. J., Lauritzen, K. H., Aspmodal, I., Christoffersen, S., Jian, L., Rasmussen, Lene Juel, Pettersen, E. O., Xiaoqun, G. & Bergersen, L. H., Jun 2012, In: Cellular oncology (Dordrecht). 35, 3, p. 217-27 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif
Andersen, S. D., Keijzers, G., Rampakakis, E., Engels, K., Luhn, P., El-Shemerly, M., Nielsen, Finn Cilius, Du, Y., May, A., Bohr, Vilhelm, Ferrari, S., Zannis-Hadjopoulos, M., Fu, H. & Rasmussen, Lene Juel, Mar 2012, In: D N A Repair. 11, 3, p. 267-77 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A rapid and cell-free assay to test the activity of lynch syndrome-associated MSH2 and MSH6 missense variants
Drost, M., Zonneveld, J. B. M., van Hees, S., Rasmussen, Lene Juel, Hofstra, R. M. W. & de Wind, N., 2012, In: Human Mutation. 33, 3, p. 488-94 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide screens for expressed hypothetical proteins
Desler, Claus, Durhuus, J. A. & Rasmussen, Lene Juel, 2012, In: Methods in molecular biology (Clifton, N.J.). 815, p. 25-38 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is There a Link between Mitochondrial Reserve Respiratory Capacity and Aging?
Hansen, T. L., Rasmussen, Lene Juel, Desler, Claus, Frederiksen, J. B., Espersen, M. L. M. & Singh, K. K., 2012, In: Journal of Aging Research. 2012, p. 192503 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Aging, longevity and health
Rasmussen, Lene Juel, Sander, M., Wewer, Ulla M. & Bohr, Vilhelm, 23 Jul 2011, In: Mechanisms of Ageing and Development. p. 522-32 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The importance of mitochondrial DNA in aging and cancer
Desler, Claus, Espersen, M. L. M., Singh, K. K. & Rasmussen, Lene Juel, 30 Mar 2011, In: Journal of Aging Research. 2011, p. 407536Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks
Liberti, S. E., Andersen, S. D., Wang, J., May, A., Miron, S., Perderiset, M., Keijzers, G., Nielsen, Finn Cilius, Charbonnier, J., Bohr, Vilhelm & Rasmussen, Lene Juel, 2 Jan 2011, In: DNA Repair. 10, 1, p. 73-86 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of the antimicrobial susceptibility of the ionizing radiation-resistant bacterium Deinococcus radiodurans: implications for bioremediation of radioactive waste
Bouchami, O., Sghaier, H., Desler, Claus, Lazim, H., Saidi, M., Rasmussen, Lene Juel & Ben Hassan, A., 2011, In: Annals of Microbiology.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
The effect of mitochondrial dysfunction on cytosolic nucleotide metabolism
Desler, Claus, Lykke, A. & Rasmussen, Lene Juel, 1 Jan 2010, In: Journal of Nucleic Acids. 2010Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Helicobacter pylori infection generates genetic instability in gastric cells
Machado, A. M. D., Figueiredo, C., Seruca, R. & Rasmussen, Lene Juel, 2010, In: BBA General Subjects. 1806, 1, p. 58-65 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thymidine kinase 1 deficient cells show increased survival rate after UV-induced DNA damage
Skovgaard, T., Rasmussen, Lene Juel & Munch-Petersen, B., 2010, In: Nucleosides, Nucleotides and Nucleic Acids. 29, 4-6, p. 347-51 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Biochemical characterization of MLH3 missense mutations does not reveal an apparent role of MLH3 in Lynch syndrome
Ou, J., Rasmussen, M., Westers, H., Andersen, S. D., Jager, P. O., Kooi, K. A., Niessen, R. C., Eggen, B. J. L., Nielsen, Finn Cilius, Kleibeuker, J. H., Sijmons, R. H., Rasmussen, Lene Juel & Hofstra, R. M. W., 2009, In: Genes, Chromosomes & Cancer. 48, 4, p. 340-50 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of a highly conserved binding site of Mlh1 required for exonuclease I-dependent mismatch repair
Dherin, C., Gueneau, E., Francin, M., Nunez, M., Miron, S., Liberti, S. E., Rasmussen, Lene Juel, Zinn-Justin, S., Gilquin, B., Charbonnier, J. & Boiteux, S., 2009, In: Molecular and Cellular Biology. 29, 3, p. 907-18 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential expression of hMLH1 in sporadic human colorectal cancer tumors and distant metastases
Larsen, N. B., Heiberg Engel, P. J., Rasmussen, M. & Rasmussen, Lene Juel, 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 11, p. 839-48 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Helicobacter pylori infection induces genetic instability of nuclear and mitochondrial DNA in gastric cells
Machado, A. M. D., Figueiredo, C., Touati, E., Máximo, V., Sousa, S., Michel, V., Carneiro, F., Nielsen, Finn Cilius, Seruca, R. & Rasmussen, Lene Juel, 2009, In: Clinical Cancer Research. 15, 9, p. 2995-3002 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Silico screening for functional candidates amongst hypothetical proteins
Desler, Claus, Suravajhala, P., Sanderhoff, M., Rasmussen, M. & Rasmussen, Lene Juel, 2009, In: BMC Bioinformatics. 10, p. 289Research output: Contribution to journal › Journal article › Research › peer-review
Novel DNA mismatch-repair activity involving YB-1 in human mitochondria
de Souza-Pinto, N. C., Mason, P. A., Hashiguchi, K., Weissman, L., Tian, J., Guay, D., Lebel, M., Stevnsner, T. V., Rasmussen, Lene Juel & Bohr, V. A., 2009, In: DNA Repair. 8, 6, p. 704-19 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nuclear translocation contributes to regulation of DNA excision repair activities
Knudsen, N. Ø., Andersen, S. D., Lützen, A., Nielsen, Finn Cilius & Rasmussen, Lene Juel, 2009, In: DNA Repair. 8, 6, p. 682-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Repair of DNA damage induced by anthanthrene, a polycyclic aromatic hydrocarbon (PAH) without bay or fjord regions
Desler, Claus, Johannessen, C. & Rasmussen, Lene Juel, 2009, In: Chemico-Biological Interactions. 177, 3, p. 212-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Functional analysis of HNPCC-related missense mutations in MSH2
Lützen, A., de Wind, N., Georgijevic, D., Nielsen, Finn Cilius & Rasmussen, Lene Juel, 14 Oct 2008, In: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 645, 1-2, p. 44-55 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
Mitochondria as determinant of nucleotide pools and chromosomal stability
Desler, C., Munch-Petersen, B., Stevnsner, T., Matsui, S., Kulawiec, M., Singh, K. K. & Rasmussen, Lene Juel, 1 Dec 2007, In: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 625, 1-2, p. 112-24 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nuclear localization of human DNA mismatch repair protein exonuclease 1 (hEXO1)
Knudsen, N. Ø., Nielsen, Finn Cilius, Vinther, L., Bertelsen, R., Holten-Andersen, S., Liberti, S. E., Hofstra, R., Kooi, K. & Rasmussen, Lene Juel, 2007, In: Nucleic Acids Research. 35, 8, p. 2609-19 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
The role of mitochondrial dNTP levels in cells with reduced TK2 activity
Desler, C., Munch-Petersen, B. & Rasmussen, Lene Juel, 2006, In: Nucleosides, nucleotides & nucleic acids. 25, 9-11, p. 1171-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
Cadmium inhibits human DNA mismatch repair in vivo
Lützen, A., Liberti, S. E. & Rasmussen, Lene Juel, 13 Aug 2004, In: Biochemical and Biophysical Research Communications. 321, 1, p. 21-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Is hEXO1 a cancer predisposing gene?
Liberti, S. E. & Rasmussen, Lene Juel, Aug 2004, In: Molecular Cancer Research. 2, 8, p. 427-32 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
Heterogeneity of ductular reactions in adult rat and human liver revealed by novel expression of deleted in malignant brain tumor
Bisgaard, Hanne Cathrine, Holmskov, U., Santoni Rugiu, Eric, Nagy, P., Nielsen, O., Ott, P., Hage, E., Dalhoff, Kim, Rasmussen, Lene Juel & Tygstrup, N., 2002, In: American Journal of Pathology. 161, 4, p. 1187-1198 12 p., 64395.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heterogeneity of ductular reactions in adult rat and human liver revealed by novel expression of deleted in malignant brain tumor
Bisgaard, Hanne Cathrine, Holmskov, U., Santoni Rugiu, Eric, Nagy, P., Nielsen, O., Ott, P., Hage, E., Dalhoff, Kim, Rasmussen, Lene Juel & Tygstrup, N., 2002, In: American Journal of Pathology. 161, 4, p. 1187-1198 12 p., 64395.Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
The LipB protein is a negative regulator of dam gene expression in Escherichia coli
Vaisvila, R., Rasmussen, Lene Juel, Løbner-Olesen, Anders, von Freiesleben, U. & Marinus, M. G., 2000, In: Biochimica et Biophysica Acta, Gene Structure and Expression. 1494, 1-2, p. 43-53 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1995
Growth-rate-dependent transcription initiation from the dam P2 promoter
Rasmussen, Lene Juel, Løbner-Olesen, Anders & Marinus, M. G., 1995, In: Gene. 157, 1-2, p. 213-215 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1994
- Published
Novel growth rate control of dam gene expression in Escherichia coli
Rasmussen, Lene Juel, Marinus, M. G. & Løbner-Olesen, Anders, 1994, In: Molecular Microbiology. 12, 4, p. 631-638 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 13558388
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Is There a Link between Mitochondrial Reserve Respiratory Capacity and Aging?
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Enterococcus faecalis infection causes inflammation, intracellular oxphos-independent ROS production, and DNA damage in human gastric cancer cells
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LIFESTAT – Living with statins: An interdisciplinary project on the use of statins as a cholesterol-lowering treatment and for cardiovascular risk reduction
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