Knud Jørgen Jensen

Knud Jørgen Jensen

Professor

Member of:


    1. 2023
    2. Published

      Bioconjugation of a Near-Infrared DNA-Stabilized Silver Nanocluster to Peptides and Human Insulin by Copper-Free Click Chemistry

      Rück, Vanessa, Mishra, N. K., Sørensen, K. K., Liisberg, M. B., Sloth, Ane Beth, Cerretani, Cecilia, Mollerup, Christian Brinch, Kjær, Andreas, Lou, C., Jensen, Knud Jørgen & Vosch, Tom, 2023, In: Journal of the American Chemical Society. 145, 30, p. 16771–16777 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Ca2+-Responsive Glyco-insulin

      Wu, S., Østergaard, M., Fredholt, Freja, Christensen, Niels Johan, Sørensen, K. K., Mishra, N. K., Nielsen, Hanne Mørck & Jensen, Knud Jørgen, 2023, In: Bioconjugate Chemistry. 34, 3, p. 518–528

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Enhanced hexamerization of insulin via assembly pathway rerouting revealed by single particle studies

      Bohr, Freja Schmidt-Rasmussen, Bohr, S. S. R., Mishra, N. K., González-Foutel, N. S., Pinholt, H. D., Wu, S., Nielsen, E. M., Zhang, Min, Kjaergaard, M., Jensen, Knud Jørgen & Hatzakis, Nikos, 2023, In: Communications Biology . 6, 1, 14 p., 178.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. 2022
    6. Published

      Chirality transmission in macromolecular domains

      Pandey, S., Mandal, S., Danielsen, M. B., Brown, A., Hu, C., Christensen, Niels Johan, Kulakova, A. V., Song, S., Brown, T., Jensen, Knud Jørgen, Wengel, J., Lou, C. & Mao, H., 2022, In: Nature Communications. 13, 1, 11 p., 76.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Highly Selective Lysine Acylation in Proteins Using a Lys-His Tag Sequence

      Kofoed, C., Wu, S., Sørensen, K. K., Treiberg, Tuule, Arnsdorf, J., Bjørn, S. P., Jensen, T. L., Voldborg, B. G., Thygesen, Mikkel Boas, Jensen, Knud Jørgen & Schoffelen, S., 2022, In: Chemistry: A European Journal. 28, 15, 5 p., e202200147.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Metal-ion coordinated self-assembly of human insulin directs kinetics of insulin release as determined by preclinical SPECT/CT imaging

      Engudar, G., Rodríguez-Rodríguez, C., Mishra, N. K., Bergamo, M., Amouroux, G., Jensen, Knud Jørgen, Saatchi, K. & Häfeli, U. O., 2022, In: Journal of Controlled Release. 343, p. 347-360

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Reconstructing the Origins of the Somatostatin and Allatostatin-C Signaling Systems Using the Accelerated Evolution of Biodiverse Cone Snail Toxins

      Koch, T. L., Ramiro, Iris Bea L. , Flórez Salcedo, P., Engholm, E., Jensen, Knud Jørgen, Chase, K., Olivera, B. M., Bjørn-Yoshimoto, Walden, Safavi-hemami, H. & True, J. (ed.), 2022, In: Molecular Biology and Evolution. 39, 4, 20 p., msac075.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Selective Acylation of Proteins at Gly and Lys in His Tags

      Jensen, Knud Jørgen, Thygesen, Mikkel Boas, Sorensen, K. K., Wu, S., Treiberg, Tuule & Schoffelen, S., 2022, In: ChemBioChem. 23, 24, 6 p., 202200359.

      Research output: Contribution to journalLetterResearchpeer-review

    11. 2021
    12. Published

      An Aldehyde Responsive, Cleavable Linker for Glucose Responsive Insulins

      Mannerstedt, K., Mishra, N. K., Engholm, E., Lundh, M., Madsen, C. S., Pedersen, P. J., Le‐huu, P., Pedersen, S. L., Buch‐månson, N., Borgström, B., Brimert, T., Fink, L. N., Fosgerau, K., Vrang, N. & Jensen, Knud Jørgen, 2021, In: Chemistry: A European Journal. 27, 9, p. 3166-3176 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Carbohydrate-Derived Metal-Chelator-Triggered Lipids for Liposomal Drug Delivery

      Holmstrøm, T., Galsgaard Malle, M., Wu, S., Jensen, Knud Jørgen, Hatzakis, Nikos & Pedersen, Christian Marcus, 2021, In: Chemistry - A European Journal. 27, 23, p. 6917-6922 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Controlling the fractal dimension in self-assembly of terpyridine modified insulin by Fe2+ and Eu3+ to direct in vivo effects

      Mishra, N. K., Østergaard, M., Midtgaard, S. R., Strindberg, S. S., Winkler, S., Wu, S., Sørensen, Thomas Just, Hassenkam, Tue, Poulsen, Jens-Christian Navarro, Lo Leggio, Leila, Nielsen, Hanne Mørck, Arleth, Lise, Christensen, Niels Johan, Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2021, In: Nanoscale. 13, 18, p. 8467–8473 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      High‐Performance Reversed‐Phase Flash Chromatography Purification of Peptides and Chemically Modified Insulins

      Sørensen, K. K., Mishra, N. K., Paprocki, M. P., Mehrotra, A. & Jensen, Knud Jørgen, 2021, In: ChemBioChem. 22, 10, p. 1818–1822

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      IRDye800CW labeled uPAR-targeting peptide for fluorescence-guided glioblastoma surgery: Preclinical studies in orthotopic xenografts

      Kurbegovic, Sorel, Juhl, Karina, Sørensen, K. K., Leth, Julie Maja, Willemoe, G. L., Christensen, Anders, Adams, Yvonne, Jensen, Anja Ramstedt, von Buchwald, Christian, Skjøth-rasmussen, J., Ploug, Michael, Jensen, Knud Jørgen & Kjær, Andreas, 2021, In: Theranostics. 11, 15, p. 7159-7174 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Kinetic proofreading of lipochitooligosaccharides determines signal activation of symbiotic plant receptors

      Gysel, K., Laursen, M., Thygesen, M. B., Lironi, D., Bozsóki, Z., Hjuler, C. T., Maolanon, N. N., Cheng, J., Bjørk, P. K., Vinther, M., Madsen, L. H., Rübsam, H., Muszyński, A., Ghodrati, A., Azadi, P., Sullivan, J. T., Ronson, C. W., Jensen, K. J., Blaise, M., Radutoiu, S. & 2 others, Stougaard, J. & Andersen, K. R., 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 44, 10 p., e2111031118.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems

      Laursen, Tomas, Lam, H. Y. M., Sorensen, K. K., Tian, P., Hansen, Cecilie Ida Cetti, Groves, J. T., Jensen, Knud Jørgen & Christensen, S. M., 2021, In: Communications Biology . 4, 9 p., 1057.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Polyamine‐Functionalized 2′‐Amino‐LNA in Oligonucleotides: Facile Synthesis of New Monomers and High‐Affinity Binding towards ssDNA and dsDNA

      Danielsen, M. B., Christensen, Niels Johan, Jørgensen, P. T., Jensen, Knud Jørgen, Wengel, J. & Lou, C., 2021, In: Chemistry: A European Journal. 27, 4, p. 1416-1422 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Safety‐catch linkers for Fmoc solid‐phase synthesis of peptide thioesters and hydrazides by amide‐to‐imide activation

      Paprocki, M. P., Rasmussen, J. E., Sørensen, K. K. & Jensen, Knud Jørgen, 2021, In: Journal of Peptide Science. 27, 12, 6 p., e3364.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. 2020
    22. Published

      Ligand-recognizing motifs in plant LysM receptors are major determinants of specificity

      Bozsoki, Z., Gysel, K., Hansen, S. B., Lironi, D., Krönauer, C., Feng, F., De Jong, N., Vinther, M., Kamble, M., Thygesen, M. B., Engholm, E., Kofoed, C., Fort, S., Sullivan, J. T., Ronson, C. W., Jensen, K. J., Blaise, M., Oldroyd, G., Stougaard, J., Andersen, K. R. & 1 others, Radutoiu, S., 7 Aug 2020, In: Science. 369, 6504, p. 663-670 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      Bioimaging and Biodistribution of the Metal‐Ion‐Controlled Self‐Assembly of PYY3–36 Studied by SPECT/CT

      Kalomoiri, Panagiota, Rodríguez‐rodríguez, C., Sørensen, K. K., Bergamo, M., Saatchi, K., Häfeli, U. O. & Jensen, Knud Jørgen, 2020, In: ChemBioChem. 21, 23, p. 3338-3343 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      How Membrane Geometry Regulates Protein Sorting Independently of Mean Curvature

      Larsen, J. B., Rosholm, K. R., Kennard, C., Pedersen, S. L., Munch, H. K., Tkach, V., Sakon, J. J., Bjornholm, T., Weninger, K. R., Bendix, Poul Martin, Jensen, Knud Jørgen, Hatzakis, Nikos, Uline, M. J. & Stamou, Dimitrios, 2020, In: ACS Central Science. 6, 7, p. 1159-1168 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Self‐Assembly of DNA–Peptide Supermolecules: Coiled‐Coil Peptide Structures Templated by d‐DNA and l-DNA Triplexes Exhibit Chirality‐Independent but Orientation‐Dependent Stabilizing Cooperativity

      Lou, C., Boesen, J. T., Christensen, Niels Johan, Sørensen, K. K., Thulstrup, Peter Waaben, Pedersen, M. N., Giralt, E., Jensen, Knud Jørgen & Wengel, J., 2020, In: Chemistry: A European Journal. 26, 25, p. 5676-5684 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      Synthesis and Characterization of Adamantane-Containing Heteropeptides with a Chirality Switch

      Aloisi, A., Christensen, Niels Johan, Sorensen, K. K., Guilbaud-Chereau, C., Jensen, Knud Jørgen & Bianco, A., 2020, In: European Journal of Organic Chemistry. 2020, 7, p. 815-820

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      The ABC of Insulin: The Organic Chemistry of a Small Protein

      Østergaard, M., Mishra, N. K. & Jensen, Knud Jørgen, 2020, In: Chemistry: A European Journal. 26, 38, p. 8341-8357 17 p.

      Research output: Contribution to journalReviewResearchpeer-review

    28. Published

      Ultrasmall TPGS-PLGA Hybrid Nanoparticles for Site-Specific Delivery of Antibiotics into Pseudomonas aeruginosa Biofilms in Lungs

      Wan, F., Bohr, S. S. R., Kłodzińska, S. N., Jumaa, H., Huang, Z., Nylander, T., Thygesen, Mikkel Boas, Sørensen, K. K., Jensen, Knud Jørgen, Sternberg, C., Hatzakis, Nikos & Nielsen, Hanne Mørck, 2020, In: ACS Applied Materials and Interfaces. 12, p. 380-389

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. 2019
    30. Published

      Half-Life Extending Modifications of Peptide YY3-36 Direct Receptor-Mediated Internalization

      Bech, E. M., Kaiser, A., Bellmann-Sickert, K., Nielsen, S. S., Sørensen, K. K., Elster, L., Hatzakis, Nikos, Pedersen, S. L., Beck-Sickinger, A. G. & Jensen, Knud Jørgen, 2019, In: Molecular Pharmaceutics. 16, 8, p. 3665-3677

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. 2018
    32. Published

      Selective N-terminal acylation of peptides and proteins with a Gly-His tag sequence

      Martos Maldonado, M. C., Hjuler, C. T., Sørensen, K. K., Thygesen, Mikkel Boas, Rasmussen, J. E., Villadsen, K., Midtgaard, S. R., Kol, S., Schoffelen, S. & Jensen, Knud Jørgen, 1 Dec 2018, In: Nature Communications. 9, 13 p., 3307 .

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published

      Chemical Strategies for Half-Life Extension of Biopharmaceuticals: Lipidation and Its Alternatives

      Bech, E. M., Pedersen, S. L. & Jensen, Knud Jørgen, 12 Jul 2018, In: ACS Medicinal Chemistry Letters. 9, 7, p. 577-580 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. Published

      A plant chitinase controls cortical infection thread progression and nitrogen-fixing symbiosis

      Malolepszy, A., Kelly, S., Sørensen, K. K., James, E. K., Kalisch, C., Bozsoki, Z., Panting, M., Andersen, S. U., Sato, S., Tao, K., Jensen, D. B., Vinther, M., Jong, N. D., Madsen, L. H., Umehara, Y., Gysel, K., Berentsen, M. U., Blaise, M., Jensen, K. J., Thygesen, M. B. & 3 others, Sandal, N., Andersen, K. R. & Radutoiu, S., 2018, In: eLife. 7, p. 1-17 17 p., e38874.

      Research output: Contribution to journalJournal articleResearchpeer-review

    35. Published

      Brain-Targeting Delivery of Two Peptidylic Inhibitors for Their Combination Therapy in Transgenic Polyglutamine Disease Mice via Intranasal Administration

      Yang, M., Zhang, Q., Wang, Q., Sørensen, K. K., Boesen, J. T., Ma, S. Y., Jensen, Knud Jørgen, Kwan, K. M., Ngo, J. C. K., Chan, H. Y. E. & Zuo, Z., 2018, In: Molecular Pharmaceutics. 15, 12, p. 5781-5792 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. Published

      Epidermal LysM receptor ensures robust symbiotic signalling in Lotus japonicus

      Murakami, E., Cheng, J., Gysel, K., Bozsoki, Z., Kawaharada, Y., Hjuler, C. T., Sørensen, K. K., Tao, K., Kelly, S., Venice, F., Genre, A., Thygesen, M. B., de Jong, N., Vinther, M., Jensen, D. B., Jensen, K. J., Blaise, M., Madsen, L. H., Andersen, K. R., Stougaard, J. & 1 others, Radutoiu, S., 2018, In: eLife. 7, 21 p., e33506.

      Research output: Contribution to journalJournal articleResearchpeer-review

    37. Published

      Glycoconjugate Oxime Formation Catalyzed at Neutral pH: Mechanistic Insights and Applications of 1,4-Diaminobenzene as a Superior Catalyst for Complex Carbohydrates

      Østergaard, M., Christensen, Niels Johan, Hjuler, C. T., Jensen, Knud Jørgen & Thygesen, Mikkel Boas, 2018, In: Bioconjugate Chemistry. 29, 4, p. 1219-1230 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    38. Published

      Synergy of Two Highly Specific Biomolecular Recognition Events: Aligning an AT-Hook Peptide in DNA Minor Grooves via Covalent Conjugation to 2′-Amino-LNA

      Ejlersen, M., Christensen, Niels Johan, Sørensen, K. K., Jensen, Knud Jørgen, Wengel, J. & Lou, C., 2018, In: Bioconjugate Chemistry. 29, p. 1025-1029 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Published

      Videnskabelig usikkerhed i kemi: Hvad er farligt?

      Green, Sara, Emmeche, Claus & Jensen, Knud Jørgen, 2018, In: Aktuel Naturvidenskab. 6, p. 38-41 4 p.

      Research output: Contribution to journalJournal articleCommunication

    40. 2017
    41. Published

      Membrane curvature regulates ligand-specific membrane sorting of GPCRs in living cells

      Rosholm, K. R., Leijnse, Natascha, Mantsiou, A., Tkach, V., Pedersen, S. L., Wirth, V. F., Oddershede, L. B., Jensen, Knud Jørgen, Martinez, Karen Laurence, Hatzakis, Nikos, Bendix, Poul Martin, Callan-Jones, A. & Stamou, Dimitrios, 8 May 2017, In: Nature Chemical Biology. 13, 7, p. 724-729

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. Published

      A brain-targeting lipidated peptide for neutralizing RNA-mediated toxicity in Polyglutamine Diseases

      Zhang, Q., Yang, M., Sørensen, K. K., Madsen, C. S., Boesen, J. T., An, Y., Peng, S. H., Wei, Y., Wang, Q., Jensen, Knud Jørgen, Zuo, Z., Chan, H. Y. E. & Ngo, J. C. K., 2017, In: Scientific Reports. 7, 1, 13 p., 12077.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. Published

      Antisense Oligonucleotides Internally Labeled with Peptides Show Improved Target Recognition and Stability to Enzymatic Degradation

      Taskova, M., Madsen, C. S., Jensen, Knud Jørgen, Hansen, L. H., Vester, B. & Astakhova, K., 2017, In: Bioconjugate Chemistry. 28, 3, p. 768-774 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    44. Published

      Chemoselective Reactions for the Synthesis of Glycoconjugates from Unprotected Carbohydrates

      Villadsen, K., Martos Maldonado, M. C., Jensen, Knud Jørgen & Thygesen, Mikkel Boas, 2017, In: ChemBioChem. 18, 7, p. 574-612 39 p.

      Research output: Contribution to journalReviewResearchpeer-review

    45. Published

      Folding Topology of a Short Coiled-Coil Peptide Structure Templated by an Oligonucleotide Triplex

      Lou, C., Christensen, Niels Johan, Martos Maldonado, M. C., Midtgaard, S. R., Ejlersen, M., Thulstrup, Peter Waaben, Sørensen, K. K., Jensen, Knud Jørgen & Wengel, J., 2017, In: Chemistry - A European Journal. 23, 39, p. 9297-9305 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. Published

      GUB06-046, a novel secretin/glucagon-like peptide 1 co-agonist, decreases food intake, improves glycemic control, and preserves beta cell mass in diabetic mice

      van Witteloostuijn, S. B., Dalboge, L. S., Hansen, G., Midtgaard, S. R., Jensen, G. V., Jensen, Knud Jørgen, Vrang, N., Jelsing, J. & Pedersen, S. L., 2017, In: Journal of Peptide Science. 23, 12, p. 845-854 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. Published

      Inside Cover: Chemoselective Reactions for the Synthesis of Glycoconjugates from Unprotected Carbohydrates

      Villadsen, K., Martos Maldonado, M. C., Jensen, Knud Jørgen & Thygesen, Mikkel Boas, 2017, In: ChemBioChem. 18, 7, p. 573 1 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. Published

      Integrin targeting and toxicological assessment of peptide-conjugated liposome delivery systems to activated endothelial cells

      Kermanizadeh, A., Villadsen, K., Østrem, R. G., Jensen, Knud Jørgen, Møller, Peter & Loft, Steffen, 2017, In: Basic & Clinical Pharmacology & Toxicology. 120, 4, p. 380-389 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    49. Published

      Linear Multiepitope (Glyco)peptides for Type-Specific Serology of Herpes Simplex Virus (HSV) Infections

      Risinger, C. W., Sørensen, K. K., Jensen, Knud Jørgen, Olofsson, S., Bergström, T. & Blixt, K. O., 2017, In: ACS Infectious Diseases. 3, 5, p. 360-367 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    50. Published

      Membrane Curvature and Lipid Composition Synergize To Regulate N-Ras Anchor Recruitment

      Larsen, J. B., Kennard, C., Pedersen, S. L., Jensen, Knud Jørgen, Uline, M. J., Hatzakis, Nikos & Stamou, Dimitrios, 2017, In: Biophysical Journal. 113, 6, p. 1269-1279 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    51. Published

      Neoglycolipids for Prolonging the Effects of Peptides: Self-Assembling Glucagon-like Peptide 1 Analogues with Albumin Binding Properties and Potent in Vivo Efficacy

      van Witteloostuijn, S. B., Mannerstedt, K. M. S., Wismann, P., Bech, E. M., Thygesen, Mikkel Boas, Vrang, N., Jelsing, J., Jensen, Knud Jørgen & Pedersen, S. L., 2017, In: Molecular Pharmaceutics. 14, 1, p. 193-205 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    52. Published

      Peptide Half-Life Extension: Divalent, Small-Molecule Albumin Interactions Direct the Systemic Properties of Glucagon-Like Peptide 1 (GLP-1) Analogues

      Bech, E. M., Martos-Maldonado, M. C., Wismann, P., Sorensen, K. K., van Witteloostuijn, S. B., Thygesen, Mikkel Boas, Vrang, N., Jelsing, J., Pedersen, S. L. & Jensen, Knud Jørgen, 2017, In: Journal of Medicinal Chemistry. 60, 17, p. 7434-7446 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    53. Published

      Preparation of glycoconjugates from unprotected carbohydrates for protein-binding studies

      Hjuler, C. T., Maolanon, N. N., Sauer, J., Stougaard, J., Thygesen, Mikkel Boas & Jensen, Knud Jørgen, 2017, In: Nature Protocols (Print). 12, 11, p. 2411-2422 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    54. 2016
    55. Published

      Carbohydrate-modified gold nanoparticles

      Thygesen, Mikkel Boas & Jensen, Knud Jørgen, 2016, Carbohydrate nanotechnology. J. Stine, K. (ed.). Wiley, p. 79-98

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    56. Published

      Construction of insulin 18-mer nanoassemblies driven by coordination to Iron(II) and Zinc(II) ions at distinct sites

      Munch, H. K., Nygård, Jesper, Christensen, Niels Johan, Engelbrekt, C., Østergaard, M., Porsgaard, T., Hoeg-Jensen, T., Zhang, J., Arleth, Lise, Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2016, In: Angewandte Chemie International Edition. 55, 7, p. 2378-2381 4 p.

      Research output: Contribution to journalLetterResearchpeer-review

    57. Published

      Dimeric peptides with three different linkers self-assemble with phospholipids to form peptide nanodiscs that stabilize membrane proteins

      Nørgrd Larsen, Andreas, Sørensen, K. K., Johansen, Nicolai Tidemand, Martel, A., Kirkensgaard, Jacob Judas Kain, Jensen, Knud Jørgen, Arleth, Lise & Midtgaard, S. R., 2016, In: Soft Matter. 12, 27, p. 5937-5949 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    58. Published

      Half-life extension of biopharmaceuticals using chemical methods: alternatives to PEGylation

      van Witteloostuijn, S. B., Pedersen, S. L. & Jensen, Knud Jørgen, 2016, In: ChemMedChem. 11, 22, p. 2474-2495 22 p.

      Research output: Contribution to journalReviewResearchpeer-review

    59. Published

      Large-scale biophysical evaluation of protein PEGylation effects: in vitro properties of 61 protein entities

      Vernet, E., Popa, G., Pozdnyakova, I., Rasmussen, J. E., Grohganz, Holger, Giehm, L., Jensen, M. H., Wang, H., Plesner, B., Nielsen, Hanne Mørck, Jensen, Knud Jørgen, Berthelsen, J., Sundström, M. & van de Weert, Marco, 2016, In: Molecular Pharmaceutics. 13, 5, p. 1587-1598 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    60. Published

      N-RAS lipid anchor adsorption to membranes as a function of lipid composition and curvature

      Larsen, J. B., Kennard, C., Pedersen, S. L., Jensen, Knud Jørgen, Hatzakis, Nikos, Uline, M. J. & Stamou, Dimitrios, 2016, In: Biophysical Society. Annual Meeting. Abstracts. 110, 3, p. 579A 1 p.

      Research output: Contribution to journalConference abstract in journalResearch

    61. Published

      Peptide-stabilized, fluorescent silver nanoclusters: solid-phase synthesis and screening

      Gregersen, S., Vosch, Tom & Jensen, Knud Jørgen, 2016, In: Chemistry: A European Journal. 22, 51, p. 18492-18500 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    62. Published

      Peptide–oligonucleotide conjugates as nanoscale building blocks for assembly of an artificial three-helix protein mimic

      Lou, C., Martos Maldonado, M. C., Madsen, C. S., Thomsen, R. P., Midtgaard, S. R., Christensen, Niels Johan, Kjems, J., Thulstrup, Peter Waaben, Wengel, J. & Jensen, Knud Jørgen, 2016, In: Nature Communications. 7, 9 p., 12294.

      Research output: Contribution to journalJournal articleResearchpeer-review

    63. Published

      tN-Ras, Synaptotagmin1 C2Ab, Annexinb12 and Amphiphysin NBAR can Discriminate Spherical from Cylindrical Membrane Curvature

      Breuer, A., Larsen, J., Rosholm, K. R., Pedersenb, S. L., Munch, H. K., Tkach, V., Sakon, J. J., Bjornholm, T., Weninger, K. R., Bendix, Poul Martin, Jensen, Knud Jørgen, Uline, M. J., Hatzakis, Nikos & Stamou, Dimitrios, 2016, In: Biophysical Journal. 110, 3, 1 p.

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    64. 2015
    65. Published

      A de novo designed monomeric, compact three helix bundle protein on a carbohydrate template

      Malik, L., Nygård, Jesper, Christensen, Niels Johan, Madsen, C. S., Rösner, Heike Ilona, Kragelund, Birthe Brandt, Høiberg-Nielsen, R., Streicher, W., Arleth, Lise, Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2015, In: ChemBioChem. 16, 13, p. 1905-1918 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    66. Published

      Additional disulfide bonds in insulin: prediction, recombinant expression, receptor binding affinity, and stability

      Vinther, T. N., Pettersson, I., Huus, K., Schlein, M., Steensgaard, D. B., Sørensen, A., Jensen, Knud Jørgen, Kjeldsen, T. & Hubalek, F., 2015, In: Protein Science. 24, 5, p. 779-788 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    67. Published

      An intermolecular binding mechanism involving multiple LysM domains mediates carbohydrate recognition by an endopeptidase

      Wong, M. M. J. E., Midtgaard, S. R., Gysel, K., Thygesen, Mikkel Boas, Sørensen, K. K., Jensen, Knud Jørgen, Stougaard, J., Thirup, S. S. & Blaise, M., 2015, In: Acta Crystallographica. Section D: Biological Crystallography. 71, p. 592-605 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    68. Published

      Antimicrobial peptide shows enhanced activity and reduced toxicity upon grafting to chitosan polymers

      Sahariah, P., Sørensen, K. K., Hjálmarsdóttir, M. Á., Sigurjónsson, Ó. E., Jensen, Knud Jørgen, Másson, M. & Thygesen, Mikkel Boas, 2015, In: Chemical Communications. 51, 58, p. 11611-11614 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    69. Published

      Distinctive binding modes and inhibitory mechanisms of two peptidic inhibitors of urokinase-type plasminogen activator with isomeric P1 residues

      Jiang, L., Zhao, B., Xu, P., Sørensen, H. P., Jensen, J. K., Christensen, A., Hosseini, M., Nielsen, N. C., Jensen, Knud Jørgen, Andreasen, P. & Huang, M., 2015, In: International Journal of Biochemistry & Cell Biology. 62, p. 88-92 5 p.

      Research output: Contribution to journalLetterResearchpeer-review

    70. Published

      Expression, receptor binding, and biophysical characterization of guinea pig insulin desB30: a monomeric insulin variant

      Engholm, E., Hansen, Thomas Hesselhøj, Johansson, E., Strauss, H. M., Vinther, T. N., Jensen, Knud Jørgen, Hubálek, F. & Kjeldsen, T. B., 2015, In: ChemBioChem. 16, 6, p. 954-958 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    71. Published

      Impact of chain length on antibacterial activity and hemocompatibility of quaternary N-alkyl and N,N-dialkyl chitosan derivatives

      Sahariah, P., Benediktssdóttir, B. E., Hjálmarsdóttir, M. Á., Sigurjonsson, O. E., Sørensen, K. K., Thygesen, Mikkel Boas, Jensen, Knud Jørgen & Másson, M., 2015, In: Biomacromolecules. 16, 5, p. 1449-1460 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    72. Published

      Membrane curvature enables N-Ras lipid anchor sorting to liquid-ordered membrane phases

      Larsen, J. B., Jensen, M. B., Bhatia, V. K., Pedersen, S. L., Bjørnholm, T., Iversen, L., Uline, M., Szleifer, I., Jensen, Knud Jørgen, Hatzakis, Nikos & Stamou, Dimitrios, 2015, In: Nature Chemical Biology. 11, 3, p. 192-194 3 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    73. Published

      Receptor-mediated exopolysaccharide perception controls bacterial infection

      Kawaharada, Y., Kelly, S., Wibroe Nielsen, M., Hjuler, C. T., Gysel, K., Muszyński, A., Carlson, R. W., Thygesen, Mikkel Boas, Sandal, N., Asmussen, M. H., Vinther, M., Andersen, S. U., Krusell, L., Thirup, S., Jensen, Knud Jørgen, Ronson, C. W., Blaise, M., Radutoiu, S. & Stougaard, J., 2015, In: Nature. 523, 7560, p. 308-312 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    74. Published

      Selection of high-affinity peptidic serine protease inhibitors with increased binding entropy from a back-flip library of peptide-protease fusions

      Sørensen, H. P., Xu, P., Jiang, L., Kromann-Hansen, T., Jensen, Knud Jørgen, Huang, M. & Andreasen, P. A., 2015, In: Journal of Molecular Biology. 427, 19, p. 3110-3122 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    75. Published

      Synthesis and evaluation of novel lipidated neuromedin U analogs with increased stability and effects on food intake

      Dalbøge, L. S., Pedersen, S. L., van Witteloostuijn, S. B., Rasmussen, J. E., Rigbolt, K. T. G., Jensen, Knud Jørgen, Holst, B., Vrang, N. & Jelsing, J., 2015, In: Journal of Peptide Science. 21, 2, p. 85-94 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    76. Published

      The road to the first, fully active and more stable human insulin variant with an additional disulfide bond

      Vinther, T. N., Kjeldsen, T. B., Jensen, Knud Jørgen & Hubálek, F., 2015, In: Journal of Peptide Science. 21, 11, p. 797-806 10 p.

      Research output: Contribution to journalReviewResearchpeer-review

    77. Published

      Ultramild protein-mediated click chemistry creates efficient oligonucleotide probes for targeting and detecting nucleic acids

      Nåbo, L. J., Madsen, C. S., Jensen, Knud Jørgen, Kongsted, J. & Astakhova, K., 2015, In: ChemBioChem. 16, 8, p. 1163-1167 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    78. 2014
    79. Published

      Self-assembling peptides form nanodiscs that stabilize membrane proteins

      Midtgaard, S. R., Pedersen, M. C., Kirkensgaard, Jacob Judas Kain, Sørensen, K. K., Mortensen, Kell, Jensen, Knud Jørgen & Arleth, Lise, 1 Jan 2014, In: Soft Matter. 10, 5, p. 738-752 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    80. Published

      A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility

      Zhao, B., Xu, P., Jiang, L., Jensen, B. P., Kromann-Hansen, T., Jensen, J. K., Sorensen, H. P., Liu, Z., Nielsen, J. T., Christensen, A., Hosseini, M., Sørensen, K. K., Nielsen, N. C., Jensen, Knud Jørgen, Huang, M. & Andreasen, P., 2014, In: PLOS ONE. 9, 12, 27 p., e115872.

      Research output: Contribution to journalJournal articleResearchpeer-review

    81. Published

      Chemically synthesized 58-mer LysM domain binds lipochitin oligosaccharide

      Sørensen, K. K., Simonsen, J. B., Maolanon, N. N., Stougaard, J. & Jensen, Knud Jørgen, 2014, In: ChemBioChem. 15, 14, p. 2097-2105 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    82. Published

      How membrane curvature drives the up-concentration of N-Ras proteins to ordered lipid domains: correlation of in vivo and in vitro experiments with mean field theory calculations and coarse grain simulations

      Hatzakis, Nikos, Larsen, J. B., Jensen, M. B., Bhatia, V. K., Pedersen, S. L., Koldsoe, H., Fowler, P., Uline, M. J., Szleifer, I. G., Bjørnholm, T., Sansom, M., Jensen, Knud Jørgen & Stamou, Dimitrios, 2014, In: Biophysical Society. Annual Meeting. Abstracts. 106, 2, p. 713a 1 p.

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    83. Published

      Lipochitin oligosaccharides immobilized through oximes in glycan microarrays bind LysM proteins

      Maolanon, N. N., Blaise, M., Sørensen, K. K., Thygesen, Mikkel Boas, Clo, E., Sullivan, J. T., Ronson, C. W., Stougaard, J., Blixt, K. O. & Jensen, Knud Jørgen, 2014, In: ChemBioChem. 15, 3, p. 425-434 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    84. 2013
    85. Published

      Backbone amide linker strategy: protocols for the synthesis of C-terminal peptide aldehydes

      Shelton, A. P. T. & Jensen, Knud Jørgen, 2013, Peptide synthesis and applications. Jensen, K. J., Shelton, P. T. & Pedersen, S. L. (eds.). Humana Press, p. 131-139 9 p. (Methods in Molecular Biology, Vol. 1047).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    86. Published

      Bicyclic peptide inhibitor of urokinase-type plasminogen activator: mode of action

      Roodbeen, R., Jensen, B. P., Jiang, L., Jensen, J. K., Christensen, A., Nielsen, J. T., Huang, M., Mulder, F., Nielsen, N. C., Andreasen, P. & Jensen, Knud Jørgen, 2013, In: ChemBioChem. 14, 16, p. 2179-2188 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    87. Published

      COMU: scope and limitations of the latest innovation in peptide acyl transfer reagents

      Subirós-Funosas, R., Nieto-Rodriguez, L., Jensen, Knud Jørgen & Albericio, F., 2013, In: Journal of Peptide Science. 19, 7, p. 408-414 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    88. Published

      Gold-ferrocene glyco-nanoparticles for high-sensitivity electrochemical detection of carbohydrate-lectin interactions

      Martos Maldonado, M. C., Thygesen, Mikkel Boas, Jensen, Knud Jørgen & Vargas-Berenguel, A., 2013, In: European Journal of Organic Chemistry. 2013, 14, p. 2793-2801 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    89. Published

      Improved PET Imaging of uPAR expression using new Cu-64-labeled cross-bridged peptide ligands: comparative in vitro and in vivo studies

      Persson, M., Hosseini, M., Madsen, J., Jørgensen, T. J. D., Jensen, Knud Jørgen, Kjær, Andreas & Ploug, Michael, 2013, In: Theranostics. 3, 9, p. 618-632 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    90. Published

      Instruments for automated peptide synthesis

      Pedersen, S. L. & Jensen, Knud Jørgen, 2013, Peptide synthesis and applications. Jensen, K. J., Shelton, P. T. & Pedersen, S. L. (eds.). Humana Press, p. 215-224 10 p. (Methods in Molecular Biology, Vol. 1047).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    91. Published

      Insulin analog with additional disulfide bond has increased stability and preserved activity

      Vinther, T. N., Norrman, M., Ribel, U., Huus, K., Schlein, M., Steensgaard, D. B., Pedersen, T. Å., Pettersson, I., Ludvigsen, S., Kjeldsen, T., Jensen, Knud Jørgen & Hubálek, F., 2013, In: Protein Science. 22, 3, p. 296-305 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    92. Published

      Kinetic analysis of inhibition of glucoamylase and active site mutants via chemoselective oxime immobilization of acarbose on SPR chip surfaces

      Sauer, J., Abou Hachem, M., Svensson, B., Jensen, Knud Jørgen & Thygesen, Mikkel Boas, 2013, In: Carbohydrate Research. 375, p. 21-28 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    93. Published

      Leonidas Zervas award lecture: Abiotic ligands for new quaternary architectures of peptides and proteins

      Jensen, Knud Jørgen, 2013, In: Journal of Peptide Science. 19, 9, p. 537-544 8 p.

      Research output: Contribution to journalReviewResearchpeer-review

    94. Published

      Linkers, resins, and general procedures for solid-phase peptide synthesis

      Shelton, A. P. T. & Jensen, Knud Jørgen, 2013, Peptide synthesis and applications. Jensen, K. J., Shelton, P. T. & Pedersen, S. L. (eds.). Humana Press, p. 23-41 19 p. (Methods in Molecular Biology, Vol. 1047).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    95. Published

      Lipid-Anchored Ras is Sorted by Membrane Curvature Both In Vitro and in Living Cells

      Larsen, J., Jensen, M. B., Bhatia, V. K., Pedersen, S. L., Bjornholm, T., Jensen, Knud Jørgen, Kohnke, M., Abankwa, D., Alexandrov, K., Hatzakis, Nikos & Stamou, Dimitrios, 2013, In: Biophysical Journal. 104, 2, 1 p., 500-Pos.

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    96. Published

      Microwave-assisted solid-phase peptide synthesis using the biotage syro Wave

      Malik, L. & Jensen, Knud Jørgen, 2013, Peptide synthesis and applications. Jensen, K. J., Shelton, P. T. & Pedersen, S. L. (eds.). Humana Press, p. 225-234 10 p. (Methods in Molecular Biology, Vol. 1047).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    97. Published

      Peptide release, side-chain deprotection, work-up, and isolation

      Pedersen, S. L. & Jensen, Knud Jørgen, 2013, Peptide synthesis and applications. Jensen, K. J., Shelton, P. T. & Pedersen, S. L. (eds.). Humana Press, p. 43-63 21 p. (Methods in Molecular Biology, Vol. 1047).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    98. Published

      Self-assembly of designed coiled coil peptides studied by small-angle X-ray scattering and analytical ultracentrifugation

      Malik, L., Nygaard, J., Christensen, Niels Johan, Thulstrup, Peter Waaben, Arleth, Lise, Jensen, Knud Jørgen & Streicher, W., 2013, In: Journal of Peptide Science. 19, 5, p. 283-292 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    99. Published

      Site-selective three-component reaction for dual-functionalization of peptides

      Munch, H. K., Rasmussen, J. E., Popa, G., Christensen, Jørn Bolstad & Jensen, Knud Jørgen, 2013, In: Chemical Communications. 49, 19, p. 1936-1938 3 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    100. Published

      Solid-phase peptide synthesis: an introduction

      Jensen, Knud Jørgen, 2013, Peptide synthesis and applications. Jensen, K. J., Shelton, P. T. & Pedersen, S. L. (eds.). Humana Press, p. 1-21 21 p. (Methods in Molecular Biology, Vol. 1047).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    101. Published

      Solid-phase synthesis of phosphopeptides

      Højlys-Larsen, K. B. & Jensen, Knud Jørgen, 2013, Peptide synthesis and applications. Jensen, K. J., Shelton, P. T. & Pedersen, S. L. (eds.). Humana Press, p. 191-199 9 p. (Methods in Molecular Biology, Vol. 1047).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    102. Published

      Sorting of tN-Ras by Membrane Curvature in Lipid Vesicles and Tubes

      Rosholm, K. R., Larsen, J., Pedersen, S. L., Munch, H. K., Jensen, Knud Jørgen, Hatzakis, Nikos & Stamou, Dimitrios, 2013, In: Biophysical Journal. 104, Supplement 1, p. 549A 1 p.

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    103. Published

      Synthesis of C-terminal peptide thioesters using Fmoc-based solid-phase peptide chemistry

      Shelton, A. P. T. & Jensen, Knud Jørgen, 2013, Peptide synthesis and applications. Jensen, K. J., Shelton, P. T. & Pedersen, S. L. (eds.). Humana Press, p. 119-129 11 p. (Methods in Molecular Biology, Vol. 1047).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    104. Published

      Synthesis of N-methylated peptides: on-resin methylation and microwave-assisted couplings

      Roodbeen, R. & Jensen, Knud Jørgen, 2013, Peptide synthesis and applications. Jensen, K. J., Shelton, P. T. & Pedersen, S. L. (eds.). Humana Press, p. 141-149 9 p. (Methods in Molecular Biology, Vol. 1047).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    105. 2012
    106. Published

      Characterization of the viral O-glycopeptidome: a novel tool of relevance for vaccine design and serodiagnosis

      Cló, E., Kracun, S. K., Nudelman, A. S., Jensen, Knud Jørgen, Liljeqvist, J., Olofsson, S., Bergström, T. & Blixt, K. O., Jun 2012, In: Journal of Virology. 86, 11, p. 6268-78 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    107. Published

      Effect of residual water and microwave heating on half-lifes of reagents and reactive intermediates in peptide synthesis

      Shelton, A. P. T., Pedersen, S. L., Stærk, Dan & Jensen, Knud Jørgen, 2012, In: Chemistry: A European Journal. 18, 29, p. 9024-9031 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    108. Published

      End-to-end assembly of gold nanorods via oligopeptide linking and surfactant control: [and] Corrigendum to “End-to-end assembly of gold nanorods via oligopeptide linking and surfactant control”

      Jain, T., Roodbeen, R., Reeler, N. E. A., Vosch, Tom, Jensen, Knud Jørgen, Bjørnholm, T. & Nørgaard, K., 2012, In: Journal of Colloid and Interface Science. 376, 1, p. 83-90 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    109. Published

      Improving membrane binding as a design strategy for amphipathic peptide hormones: 2-helix variants of PYY3-36

      Pedersen, S. L., Bhatia, V. K., Jurt, S., Paulsson, J. F., Pedersen, M. H., Jørgensen, R., Holst, Birgitte, Stamou, Dimitrios, Vrang, N., Zerbe, O. & Jensen, Knud Jørgen, 2012, In: Journal of Peptide Science. 18, 9, p. 579-587 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    110. Published

      Interconversion of active and inactive conformations of urokinase-type plasminogen activator

      Liu, Z., Kromann-Hansen, T., Lund, I. K., Hosseini, M., Jensen, Knud Jørgen, Høyer-Hansen, G., Andreasen, P. & Sørensen, H. P., 2012, In: Biochemistry. 51, 39, p. 7804-7811 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    111. Published

      Legume receptors perceive the rhizobial lipochitin oligosaccharide signal molecules by direct binding

      Broghammer, A., Krusell, L., Blaise, M., Sauer, J., Sullivan, J. T., Maolanon, N. N., Vinther, M., Lorentzen, A. M., Madsen, E. B., Jensen, Knud Jørgen, Roepstorff, P., Thirup, S. S., Ronson, C. W., Thygesen, Mikkel Boas & Stougaard, J., 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 34, p. 13859-13864 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    112. Published

      Metal ion controlled self-assembly of a chemically reengineered protein drug studied by small-angle X-ray scattering

      Nygaard, J., Munch, H. K., Thulstrup, Peter Waaben, Christensen, Niels Johan, Høeg-Jensen, T., Jensen, Knud Jørgen & Arleth, Lise, 2012, In: Langmuir. 28, 33, p. 12159-12170 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    Previous 1 2 3 Next

    ID: 4238020