Yvonne Mary Adams

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Current research

I have been actively involved in malaria research since 2002 primarly focused upon the adhesive interaction of the Plasmodium falciparum infected red blood cells and the host receptor ICAM-1. My research has investigated the mechanisms by which parasites bind to the endothelium under both static and flow conditions. Since 2018, I have used the blood-brain barrier (BBB) organoid model to investigate the imapct ICAM-1 binding parasite have on the BBB.

My other interests include:

• Adjunctive treamtents for cerebral malaria
• Blood outgrowth endothelial cells as model for host-parasite interactions
• Fluidic models of the microvasculature
• Lyme neuroborreliosis and the BBB
• Novel transport mechanisms to deliver drugs across the BBB

Member of the Lundbeck Foundation Investigator Network

Fields of interest

• Host-parasite interactions
• Adjunctive treatments for malaria infection
• Organoids for modelling brain infections

Teaching

Participate in teaching undergraduates in the “Immune response to infection” course. Developing educational videos for explaining laboratory techniques related to malaria research.

Possible conflicts of interest

None