Yvonne Mary Adams

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Current research

I have been actively involved in malaria research since 2002 primarly focused upon the adhesive interaction of the Plasmodium falciparum infected red blood cells and the host receptor ICAM-1 and how this contributes to cerebral malaria. To understand the impact infected red blood cells have on neural barriers, I use self-assembling, human dervied organoids to model the blood- brain barrier (BBB) and blood-cerebral spinal fluid (CSF) barrier (B-CSFB).  

My other interests include:

• Adjunctive treamtents for cerebral malaria
• Blood outgrowth endothelial cells 
• 3D cell culture models
• Fluidic models of the microvasculature
• Lyme neuroborreliosis and the neural barriers (BBB and B-CSFB)
• Novel transport mechanisms to deliver drugs across the BBB

Member of the Lundbeck Foundation Investigator Network

 

To learn how to make your own BBB-organoids, click here

Fields of interest

• Host-parasite interactions
• Adjunctive treatments for malaria infection
• Organoids for modelling brain infections

Teaching

Participate in teaching undergraduates in the “Immune response to infection” course. Developing educational videos for explaining laboratory techniques related to malaria research.

Possible conflicts of interest

None