Hans H. Wandall

Hans H. Wandall

Professor

Member of:


    1. Published

      Targeting Solid Cancers with a Cancer-Specific Monoclonal Antibody to Surface Expressed Aberrantly O-glycosylated Proteins

      Aasted, Mikkel Koed Møller, Groen, A. C., Keane, J. T., Dabelsteen, Sally, Tan, E., Schnabel, J., Liu, F., Lewis, H. G. S., Theodoropulos, C., Posey, A. D. & Wandall, Hans H., 2023, In: Molecular Cancer Therapeutics. 22, 10, p. 1204-1214 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    2. Published

      A Strategy for O-Glycoproteomics of Enveloped Viruses-the O-Glycoproteome of Herpes Simplex Virus Type 1

      Bagdonaite, Ieva , Nordén, R., Joshi, Hiren Jitendra, Dabelsteen, Sally, Nyström, K., Vakhrushev, Sergey, Olofsson, S. & Wandall, Hans H., 1 Apr 2015, In: P L o S Pathogens. 11, 4, p. 1-22 22 p., e1004784.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Mucin-Type O-GalNAc Glycosylation in Health and Disease

      Bagdonaite, Ieva , Pallesen, E. M. H., Nielsen, Mathias Alexander Ingemann, Bennett, Eric Paul & Wandall, Hans H., 2021, The Role of Glycosylation in Health and Disease. Springer VS, p. 25-60 36 p. (Advances in Experimental Medicine and Biology; No. 1325).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    4. Published

      Global Aspects of Viral Glycosylation

      Bagdonaite, Ieva & Wandall, Hans H., Jul 2018, In: Glycobiology. 28, 7, p. 443-467 25 p.

      Research output: Contribution to journalReviewResearchpeer-review

    5. Published

      Ectopic expression of a novel CD22 splice-variant regulates survival and proliferation in malignant T cells from cutaneous T cell lymphoma (CTCL) patients

      Bagdonaite, Ieva , Wandall, Hans H., Litvinov, I. V., Nastasi, C., Becker, J. C., Dabelsteen, Sally, Geisler, Carsten, Bonefeld, Charlotte Menne, Zhang, Q., Wasik, M. A., Zhou, Y., Sasseville, D., Ødum, Niels & Woetmann, A., 2015, In: OncoTarget. 6, 16, p. 14374-14384 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Global Mapping of O-Glycosylation of Varicella Zoster Virus, Human Cytomegalovirus, and Epstein-Barr Virus

      Bagdonaite, Ieva , Nordén, R., Joshi, Hiren Jitendra, King-Smith, S. L., Vakhrushev, Sergey, Olofsson, S. & Wandall, Hans H., 3 Jun 2016, In: The Journal of Biological Chemistry. 291, 23, p. 12014-12028 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      O-glycan initiation directs distinct biological pathways and controls epithelial differentiation

      Bagdonaite, Ieva , Pallesen, E. M. H., Ye, Z., Vakhrushev, Sergey, Marinova, I. N., Nielsen, Mathias Alexander Ingemann, Kramer, S. H., Pedersen, Stine Helene Falsig, Joshi, Hiren Jitendra, Bennett, Eric Paul, Dabelsteen, Sally & Wandall, Hans H., 2020, In: EMBO Reports. 21, 6, 17 p., e48885.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Glycoproteomics

      Bagdonaite, Ieva , Malaker, S. A., Polasky, D. A., Riley, N. M., Schjoldager, Katrine Ter-Borch Gram, Vakhrushev, Sergey, Halim, Adnan, Aoki-Kinoshita, K. F., Nesvizhskii, A. I., Bertozzi, C. R., Wandall, Hans H., Parker, B. L., Thaysen-Andersen, M. & Scott, N. E., 2022, In: Nature Reviews Methods Primers. 2, 1, 29 p., 48.

      Research output: Contribution to journalReviewResearchpeer-review

    9. Published

      Glycoengineered keratinocyte library reveals essential functions of specific glycans for all stages of HSV-1 infection

      Bagdonaite, Ieva , Marinova, I. N., Levann, Asha Maria Rudjord, Pallesen, E. M. H., King-Smith, S. L., Karlsson, R., Rømer, T. B., Chen, Yen-Hsi, Miller, Rebecca Louise, Olofsson, S., Nordén, R., Bergström, T., Dabelsteen, Sally & Wandall, Hans H., 2023, In: Nature Communications. 14, 19 p., 7000.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Global Mapping of O-Glycosylation of Human Herpesviruses

      Bagdonaite, Ieva , Norden, R., Joshi, Hiren Jitendra, King-Smith, S. L., Vakhrushev, Sergey, Olofsson, S. & Wandall, Hans H., Dec 2016, In: Glycobiology. 26, 12, p. 1408-1408

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    11. Published

      Site-specific O-glycosylation analysis of SARS-CoV-2 spike protein produced in insect and human cells

      Bagdonaite, Ieva , Thompson, A. J., Wang, X., Søgaard, M., Fougeroux, Cyrielle Elyette, Frank, M., Diedrich, J. K., Yates, J. R., Salanti, Ali, Vakhrushev, Sergey, Paulson, J. C. & Wandall, Hans H., 2021, In: Viruses. 13, 4, 551.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Viral glycoproteomes: Technologies for characterization and outlook for vaccine design

      Bagdonaite, Ieva , Vakhrushev, Sergey, Joshi, Hiren Jitendra & Wandall, Hans H., Dec 2018, In: FEBS Letters. 592, 23, p. 3898-3920

      Research output: Contribution to journalReviewResearchpeer-review

    13. Published

      Serum galectin-2, -4, and -8 are greatly increased in colon and breast cancer patients and promote cancer cell adhesion to blood vascular endothelium

      Barrow, H., Guo, X., Wandall, Hans H., Pedersen, J. W., Fu, B., Zhao, Q., Chen, C., Rhodes, J. M. & Yu, L., 15 Nov 2011, In: Clinical Cancer Research. 17, 22, p. 7035-7046 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      INDEL detection, the 'Achilles heel' of precise genome editing: a survey of methods for accurate profiling of gene editing induced indels

      Bennett, Eric Paul, Petersen, B. L., Johansen, I. E., Niu, Yiyuan, Yang, Zhang, Chamberlain, C. A., Met, Özcan, Wandall, Hans H. & Frödin, Morten, 2020, In: Nucleic Acids Research. 48, 21, p. 11958-11981 24 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      A high-throughput O-glycopeptide discovery platform for seromic profiling

      Blixt, O., Cló, E., Nudelman, A. S., Sørensen, K. K., Clausen, T., Wandall, Hans H., Livingston, P. O., Clausen, Henrik & Jensen, Knud Jørgen, 2010, In: Journal of Proteome Research. 9, 10, p. 5250-5261 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Autoantibodies to MUC1 glycopeptides cannot be used as a screening assay for early detection of breast, ovarian, lung or pancreatic cancer

      Burford, B., Gentry-Maharaj, A., Graham, R., Allen, D., Pedersen, J. W., Nudelman, A. S., Blixt, K. O., Fourkala, E. O., Bueti, D., Dawnay, A., Ford, J., Desai, R., David, L., Trinder, P., Acres, B., Schwientek, T., Gammerman, A., Reis, C. A., da Silva, L. P. M., Osório, H. & 10 others, Hallett, R., Wandall, Hans H., Mandel, Ulla, Hollingsworth, M. A., Jacobs, I., Fentiman, I., Clausen, Henrik, Taylor-Papadimitriou, J., Menon, U. & Burchell, J. M., 28 May 2013, In: B J C. 108, 10, p. 2045-55 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Mucins as biomarkers in cancer.

      Chen, K., Blixt, K. O. & Wandall, Hans H., Dec 2013, Mucins and Cancer. London: Future Medicine Ltd., p. 34-49 16 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    18. Published

      Glycosphingolipids with extended sugar chain have specialized functions in development and behavior of Drosophila

      Chen, Y., Pedersen, J. W., Wandall, Hans H., Levery, S. B., Pizette, S., Clausen, Henrik & Cohen, S. M., 2007, In: Developmental Biology. 306, 2, p. 736-49 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Glycosylation Engineering

      Clausen, Henrik, Wandall, Hans H., Steentoft, C., Stanley, P. & Schnaar, R. L., 2017, Essentials of Glycobiology. 3 ed. Cold Spring Harbor Laboratory Press

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    20. Published

      Keratinocyte growth factor mRNA expression in periodontal ligament fibroblasts.

      Dabelsteen, Sally, Wandall, Hans H., Grøn, B. & Dabelsteen, Erik, 1997, In: European Journal of Oral Sciences. 105, 6, p. 593-8 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model

      Dabelsteen, Sally, Pallesen, E. M. H., Marinova, I. N., Nielsen, Mathias Alexander Ingemann, Adamopoulou, M., Rømer, T. B., Levann, Asha Maria Rudjord, Aasted, Mikkel Koed Møller, Ye, Z., mfz219, mfz219, Bennett, Eric Paul, Büll, C., Moons, S. J., Boltje, T., Clausen, Henrik, Vakhrushev, Sergey, Bagdonaite, Ieva & Wandall, Hans H., 2020, In: Developmental Cell. 54, 5, p. 669-684.e7

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Neurofibromatosis-like phenotype in Drosophila caused by lack of glucosylceramide extension

      Dahlgaard, K., Jung, A., Qvortrup, Klaus, Clausen, Henrik, Kjærulff, Ole & Wandall, Hans H., 2012, In: Proceedings of the National Academy of Sciences USA (PNAS). 109, 18, p. 6987-92 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      High-efficiency genome editing via 2A-coupled co-expression of fluorescent proteins and zinc finger nucleases or CRISPR/Cas9 nickase pairs

      Duda, K., Lonowski, Lindsey Allison, Kofoed-Nielsen, M., Ibarra, A., Delay, C. M., Kang, Q., Yang, Zhang, Pruett-Miller, S. M., Bennett, Eric Paul, Wandall, Hans H., Davis, G. D., Hansen, S. H. & Frödin, Morten, 21 Apr 2014, In: Nucleic Acids Research. 42, 10, p. 1-16 16 p., e84.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Structure elucidation of neutral, di-, tri-, and tetraglycosylceramides from High Five cells: identification of a novel (non-arthro-series) glycosphingolipid pathway.

      Fuller, M. D., Schwientek, T., Wandall, Hans H., Pedersen, J. W., Clausen, Henrik & Levery, S. B., 2005, In: Glycobiology. 15, 12, p. 1286-301 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Mactosylceramide Prevents Glial Cell Overgrowth by Inhibiting Insulin and Fibroblast Growth Factor Receptor Signaling

      Gerdøe-Kristensen, S., Lund, Viktor Karlovich, Wandall, Hans H. & Kjærulff, Ole, 2017, In: Journal of Cellular Physiology. 232, 11, p. 3112–3127

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      Glycoproteomic analysis of seven major allergenic proteins reveals novel post-translational modifications

      Halim, Adnan, Carlsson, M. C., Mathiesen, C. B. K., Brand, S., Möller, S. R., Olsen, C. E., Vakhrushev, Sergey, Brimnes, J., Wurtzen, P. A., Ipsen, H., Petersen, Bent L & Wandall, Hans H., 2015, In: Molecular and Cellular Proteomics. 14, 1, p. 191-204 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      A glycogene mutation map for discovery of diseases of glycosylation

      Hansen, Lars, Lind-Thomsen, A., Joshi, Hiren Jitendra, Pedersen, N. B., Have, C. T., Kong, Y., Wang, S., Sparso, T., Grarup, Niels, Vester-Christensen, M. B., Schjoldager, Katrine Ter-Borch Gram, Freeze, H. H., Hansen, Torben, Pedersen, Oluf Borbye, Henrissat, B., Mandel, Ulla, Clausen, Henrik, Wandall, Hans H. & Bennett, Eric Paul, 2015, In: Glycobiology. 25, 2, p. 211-224 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      A mutation map for human glycoside hydrolase genes

      Hansen, Lars, Husein, D. M., Gericke, B., Hansen, Torben, Pedersen, Oluf Borbye, Tambe, M. A., Freeze, H. H., Naim, H. Y., Henrissat, B., Wandall, Hans H., Clausen, Henrik & Bennett, Eric Paul, 2020, In: Glycobiology. 30, 8, p. 500-515 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Published

      Golgi fragmentation: One of the earliest organelle phenotypes in Alzheimer's disease neurons

      Haukedal, H., Corsi, G. I., Gadekar, V. P., Doncheva, N. T., Kedia, S., de Haan, N., Chandrasekaran, A., Jensen, P., Schiønning, P., Vallin, S., Marlet, F. R., Poon, A., Pires, C., Agha, F. K., Wandall, H. H., Cirera, S., Simonsen, A. H., Nielsen, T. T., Nielsen, J. E., Hyttel, P. & 7 others, Muddashetty, R., Aldana, Blanca, Gorodkin, Jan, Nair, D., Meyer, M., Larsen, M. R. & Freude, Kristine, 2023, In: Frontiers in Neuroscience. 17, 17 p., 1120086.

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. Published

      The glycosphingolipid MacCer promotes synaptic bouton formation in Drosophila by interacting with Wnt

      Huang, Y., Huang, S., Di Scala, C., Wang, Q., Wandall, Hans H., Fantini, J. & Zhang, Y. Q., 2018, In: eLife. 7, 29 p., e38183.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. Published

      Isoform-specific mucin type O-glycosylation maintain epithelial homeostasis

      Bagdonaite, Ieva , E.M.H., P., K., L., Vakhrushev, Sergey, Hansen, Lars, Joshi, Hiren Jitendra, Bennett, Eric Paul, Dabelsteen, Sally & Wandall, Hans H., 2017, In: Glycoconjugate Journal. 34, Suppl. 1, p. S42 1 p., Abstract 78.

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    32. Published

      An innate antiviral pathway acting before interferons at epithelial surfaces

      Iversen, M. B., Reinert, L. S., Thomsen, M. K., Bagdonaite, I., Nandakumar, R., Cheshenko, N., Prabakaran, T., Vakhrushev, S. Y., Krzyzowska, M., Kratholm, S. K., Ruiz-Perez, F., Petersen, S. V., Goriely, S., Bibby, B. M., Eriksson, K., Ruland, J., Thomsen, A. R., Herold, B. C., Wandall, H. H., Frische, S. & 2 others, Holm, C. K. & Paludan, S. R., Feb 2016, In: Nature Immunology. 17, 2, p. 150-158 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published

      GlycoDomainViewer: A bioinformatics tool for contextual exploration of glycoproteomes

      Joshi, Hiren Jitendra, Jørgensen, A., Schjoldager, Katrine Ter-Borch Gram, Halim, Adnan, Dworkin, L. A., Steentoft, C., Wandall, Hans H., Clausen, Henrik & Vakhrushev, Sergey, 1 Mar 2018, In: Glycobiology. 28, 3, p. 131-136 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. Published

      Protein O-Galnac Glycosylation: Most Complex and Differentially Regulated PTM

      Joshi, Hiren Jitendra, Steentoft, C., Schjoldager, Katrine Ter-Borch Gram, Vakhrushev, Sergey, Wandall, Hans H. & Clausen, Henrik, 1 Jan 2015, Glycoscience: Biology and Medicine. Springer, p. 1049-1064 16 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    35. Published
    36. Published

      Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents

      Khetarpal, S. A., Schjoldager, K. T., Christoffersen, C., Raghavan, A., Edmondson, A. C., Reutter, H. M., Ahmed, B., Ouazzani, R., Peloso, G. M., Vitali, C., Zhao, W., Somasundara, A. V. H., Millar, J. S., Park, Y., Fernando, G., Livanov, V., Choi, S., Noé, E., Patel, P., Ho, S. P. & 12 others, Kirchgessner, T. G., Wandall, Hans H., Hansen, Lars, Bennett, Eric Paul, Vakhrushev, Sergey, Saleheen, D., Kathiresan, S., Brown, C. D., Abou Jamra, R., LeGuern, E., Clausen, Henrik & Rader, D. J., 9 Aug 2016, In: Cell Metabolism. 24, 2, p. 234-245 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    37. Published

      Sialylation of N-glycans affects the lipid secretion governed by specialized secretory lysosomal organelles through an effect on the V-ATPase

      Khoder-Agha, F., Song, Ming, Borre, M. T., Marinova, I. N., Ye, Z., Pedersen, Stine Helene Falsig, Dabelsteen, Sally & Wandall, Hans H., 2022, In: Glycobiology. 32, 11, p. 1012-1013 2 p., P103.

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    38. Published

      TAILS N-Terminomics and proteomics reveal complex regulation of proteolytic cleavage by O-glycosylation

      King, S. L., Goth, C. K., Eckhard, U., Joshi, Hiren Jitendra, Haue, Amalie Dahl, Vakhrushev, Sergey, Schjoldager, Katrine Ter-Borch Gram, Overall, C. M. & Wandall, Hans H., 2018, In: The Journal of Biological Chemistry. 293, 20, p. 7629-7644 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Published
    40. Published

      Sygdomsmekanismer og terapeutiske perspektiver ved neurofibromatose 1

      Kjærulff, Ole & Wandall, Hans H., 2012, In: Ugeskrift for Laeger. 174, 10, p. 642-647 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. Published

      Probing polypeptide GalNAc-transferase isoform substrate specificities by in vitro analysis

      Kong, Y., Joshi, Hiren Jitendra, Schjoldager, Katrine Ter-Borch Gram, Madsen, Thomas Daugbjerg, Gerken, T. A., Vester-Christensen, M. B., Wandall, Hans H., Bennett, Eric Paul, Levery, S. B., Vakhrushev, Sergey & Clausen, Henrik, Jan 2015, In: Glycobiology. 25, 1, p. 55-65 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. Published

      Dynamics of Indel Profiles Induced by Various CRISPR/Cas9 Delivery Methods

      Kosicki, M., Rajan, S. S., Lorenzetti, F. C., Wandall, Hans H., Narimatsu, Yoshiki, Metzakopian, E. & Bennett, Eric Paul, 2017, In: Progress in Molecular Biology and Translational Science. 152, p. 49-67 19 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. Published

      Fast and Quantitative Identification of Ex Vivo Precise Genome Targeting-Induced Indel Events by IDAA

      König, S., Yang, Zhang, Wandall, Hans H., Mussolino, C. & Bennett, Eric Paul, 2019, CRISPR Gene Editing. Luo, Y. (ed.). Humana Press, p. 45-66 22 p. (Methods in Molecular Biology, Vol. 1961).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    44. Published

      Induction of Bcl-xL-specific cytotoxic T lymphocytes in mice

      thg519, thg519, Andersen, M. H., Wandall, Hans H., Mathiesen, C. B. K., Christensen, R. E., Petersen, T. R. & Pedersen, Anders Elm, Aug 2014, In: Scandinavian Journal of Immunology. 80, 2, p. 111-120 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. Published

      Aberrantly glycosylated MUC1 is expressed on the surface of breast cancer cells and a target for antibody-dependent cell-mediated cytotoxicity

      Lavrsen, K., Madsen, C. B., Rasch, M. G., Woetmann, Anders , Ødum, Niels, Mandel, Ulla, Clausen, Henrik, Pedersen, Anders Elm & Wandall, Hans H., Apr 2013, In: Glycoconjugate Journal. 30, 3, p. 227-36 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. Published
    47. Published

      Genome editing using FACS enrichment of nuclease-expressing cells and indel detection by amplicon analysis

      Lonowski, Lindsey Allison, Narimatsu, Yoshiki, Riaz, A., Delay, C. M. E., Yang, Zhang, Niola, Francesco, Duda, K., Ober, Elke, Clausen, Henrik, Wandall, Hans H., Hansen, S. H., Bennett, Eric Paul & Frödin, Morten, Mar 2017, In: Nature Protocols. 12, 3, p. 581-603 23 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. Published

      Genetically engineered tissue to screen for glycan function in tissue formation

      M., A., E.M., P., Levann, Asha Maria Rudjord, mfz219, mfz219, T.B., R., I.N., M., Nielsen, Mathias Alexander Ingemann, Dabelsteen, Sally & Wandall, Hans H., 2017, In: Glycoconjugate Journal. 34, Suppl 1, p. S65 1 p., Abstract 132.

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    49. Published

      Potential for novel MUC1 glycopeptide-specific antibody in passive cancer immunotherapy

      Madsen, C. B., Wandall, Hans H. & Pedersen, Anders Elm, Dec 2013, In: Immunopharmacology and Immunotoxicology. 35, 6, p. 649-52 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    50. Published

      Correction: Glycan Elongation Beyond the Mucin Associated Tn Antigen Protects Tumor Cells from Immune-Mediated Killing

      Madsen, C. B., Lavrsen, K., Steentoft, C., Vester-Christensen, M. B., Clausen, Henrik, Wandall, Hans H. & Pedersen, Anders Elm, 2013, In: PLOS ONE. 8, 10, 11 p., e72413.

      Research output: Contribution to journalJournal articleResearch

    51. Published

      Glycan elongation beyond the mucin associated Tn antigen protects tumor cells from immune-mediated killing

      Madsen, C. B., Lavrsen, K., Steentoft, C., Vester-Christensen, M. B., Clausen, Henrik, Wandall, Hans H. & Pedersen, Anders Elm, 2013, In: PloS one. 8, 9, p. e72413 11 p., e72413.

      Research output: Contribution to journalJournal articleResearch

    52. Published

      Glycan-mediated modification of the immune response

      Madsen, C. B., Pedersen, Anders Elm & Wandall, Hans H., 1 Apr 2013, In: OncoImmunology. 2, 4, p. e23659

      Research output: Contribution to journalJournal articleResearchpeer-review

    53. Published

      MUC4-specific CTLs

      Madsen, C. B., Jess, P., Harndahl, M., Wandall, Hans H. & Pedersen, Anders Elm, Feb 2013, In: Immunopharmacology and Immunotoxicology. 35, 1, p. 202-203 2 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    54. Published

      Cancer associated aberrant protein o-glycosylation can modify antigen processing and immune response

      Madsen, C. B., Petersen, C., Lavrsen, K., Harndahl, M., Buus, Søren, Clausen, Henrik, Pedersen, Anders Elm & Wandall, Hans H., 2012, In: P L o S One. 7, 11, p. e50139

      Research output: Contribution to journalJournal articleResearchpeer-review

    55. Published

      Protocol for CRISPR-Cas9 modification of glycosylation in 3D organotypic skin models

      Marinova, I. N., Wandall, Hans H. & Dabelsteen, Sally, 2021, In: STAR Protocols. 2, 3, 100668.

      Research output: Contribution to journalJournal articleResearchpeer-review

    56. Published

      Genetically engineered cell factories produce glycoengineered vaccines that target antigen-presenting cells and reduce antigen-specific T-cell reactivity

      Mathiesen, C. B. K., Carlsson, M. C., Brand, S., Möller, S. R., Idorn, M., Straten, P. T., Pedersen, Anders Elm, Dabelsteen, Sally, Halim, Adnan, Würtzen, P. A., Brimnes, J., Ipsen, H., Petersen, Bent L & Wandall, Hans H., 2018, In: Journal of Allergy and Clinical Immunology. 142, 6, p. 1983-1987

      Research output: Contribution to journalLetterResearchpeer-review

    57. Published

      Partial vapor-phase hydrolysis of peptide bonds: A method for mass spectrometric determination of O-glycosylated sites in glycopeptides.

      Mirgorodskaya, E., Hassan, H., Wandall, Hans H., Clausen, Henrik & Roepstorff, P., 1999, In: Analytical Biochemistry. 269, 1, p. 54-65 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    58. Published

      UV light-induced spatial loss of sialic acid capping using a photoactivatable sialyltransferase inhibitor

      Moons, S. J., Hornikx, D. L. A. H., Aasted, Mikkel Koed Møller, Pijnenborg, J. F. A., Calzari, M., White, P. B., Narimatsu, Yoshiki, Clausen, Henrik, Wandall, Hans H., Boltje, T. J. & Büll, C., 2023, In: RSC Chemical Biology. 4, 7, p. 506-511 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    59. Published

      Identification and evolution of a plant cell wall specific glycoprotein glycosyl transferase, ExAD

      Möller, S. R., Yi, X., Vel?squez, S. M., Gille, S., Hansen, P., Poulsen, C. P., Olsen, C. E., Rejzek, M., Parsons, H. T., Yang, Zhang, Wandall, Hans H., Clausen, Henrik, Field, R. A., Pauly, M., Estevez, J. M., Harholt, J., Ulvskov, Peter & Petersen, Bent L, 2017, In: Scientific Reports. 7, 16 p., 45341.

      Research output: Contribution to journalJournal articleResearchpeer-review

    60. Published

      Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells

      Møller, S. H., Mellergaard, M., Madsen, M., Bermejo, A. V., Jepsen, Stine Dam, Hansen, M. H., Høgh, R. I., Aldana, Blanca, Desler, Claus, Rasmussen, Lene Juel, Sustarsic, E. G., Gerhart-Hines, Zach, Daskalaki, E., Wheelock, C. E., Hiron, T. K., Lin, D., O'Callaghan, C. A., Wandall, Hans H., Andresen, Lars & Skov, Søren, 2020, In: Frontiers in Immunology. 11, 22 p., 1968.

      Research output: Contribution to journalJournal articleResearchpeer-review

    61. Published

      Targeting of macrophage galactose-type C-type lectin (MGL) induces DC signaling and activation

      Napoletano, C., Zizzari, I. G., Rughetti, A., Rahimi, H., Irimura, T., Clausen, Henrik, Wandall, Hans H., Belleudi, F., Bellati, F., Pierelli, L., Frati, L. & Nuti, M., Apr 2012, In: Central-European Journal of Immunology. 42, 4, p. 936-45 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    62. Published

      Genetic glycoengineering in mammalian cells

      Narimatsu, Yoshiki, Büll, C., Chen, Yen-Hsi, Wandall, Hans H., Yang, Zhang & Clausen, Henrik, 2021, In: Journal of Biological Chemistry. 296, 25 p., 100448.

      Research output: Contribution to journalReviewResearchpeer-review

    63. Published

      A validated gRNA library for CRISPR/Cas9 targeting of the human glycosyltransferase genome

      Narimatsu, Yoshiki, Joshi, Hiren Jitendra, Zhang, Y., Gomes, C., Chen, Yen-Hsi, Lorenzetti, F., Furukawa, S., Schjoldager, Katrine Ter-Borch Gram, Hansen, Lars, Clausen, Henrik, Bennett, Eric Paul & Wandall, Hans H., 2018, In: Glycobiology. 28, 5, p. 295–305

      Research output: Contribution to journalJournal articleResearchpeer-review

    64. Published

      Influences of tumor stroma on the malignant phenotype.

      Nielsen, J. D., Moeslund, Mette, Wandall, Hans H. & Dabelsteen, Sally, 2008, In: Journal of Oral Pathology & Medicine. 37, 7, p. 412-6 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    65. Published

      Global mapping of GalNAc-T isoform-specificities and O-glycosylation site-occupancy in a tissue-forming human cell line

      Nielsen, Mathias Alexander Ingemann, de Haan, Noortje, Kightlinger, W., Ye, Z., Dabelsteen, Sally, Li, Minyan, Jewett, M. C., Bagdonaite, Ieva , Vakhrushev, Sergey & Wandall, Hans H., 2022, In: Nature Communications. 13, 17 p., 6257.

      Research output: Contribution to journalJournal articleResearchpeer-review

    66. Published

      Galectin binding to cells and glycoproteins with genetically modified glycosylation reveals galectin–glycan specificities in a natural context

      Nielsen, Mathias Alexander Ingemann, Stegmayr, J., Grant, O. C., Yang, Zhang, Nilsson, U. J., Boos, I., Carlsson, M. C., Woods, R. J., Unverzagt, C., Leffler, H. & Wandall, Hans H., 2018, In: Journal of Biological Chemistry. 293, 52, p. 20249-20262 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    67. Published

      Dissecting Context-Specific Galectin Binding Using Glycoengineered Cell Libraries

      Nielsen, Mathias Alexander Ingemann & Wandall, Hans H., 2022, Galectins : Methods and Protocols. Humana Press, p. 205-214 10 p. (Methods in Molecular Biology, Vol. 2442).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    68. Published

      Loss of a novel mucin-like epithelial glycoprotein in oral and cervical squamous cell carcinomas.

      Nielsen, P. A., Mandel, Ulla, Therkildsen, M. H., Ravn, V., David, L., Reis, C. A., Wandall, Hans H., Dabelsteen, Erik & Clausen, Henrik, 1997, In: Cancer Research. 57, 4, p. 634-40 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    69. Published

      Identification of a major human high molecular weight salivary mucin (MG1) as tracheobronchial mucin MUC5B.

      Nielsen, P. A., Bennett, Eric Paul, Wandall, Hans H., Therkildsen, M. H., Hannibal, J. & Clausen, Henrik, 1997, In: Glycobiology. 7, 3, p. 413-9 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    70. Published

      Macrophage galactose-type C-type lectin receptor for DC targeting of antitumor glycopeptide vaccines

      Nuti, M., Zizzari, I., Napoletano, C., Rughetti, A., Rahimi, H., Antonilli, M., Bellati, F., Di Costanzo, F., Irimura, T., Wandall, Hans H., Clausen, Henrik & Benedetti Panici, P., 20 May 2011, In: Journal of Clinical Oncology. 29, 15_suppl, p. e13528

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    71. Published

      Chemo-enzymatic production of O-glycopeptides for the detection of serum glycopeptide antibodies

      Nøstdal, A. & Wandall, Hans H., 2013, Immunoproteomics : Methods in Molecular Biology. Fulton, K. M. & Twine, S. M. (eds.). Humana Press, Vol. 1061. p. 167-79 13 p. (Methods in molecular biology (Clifton, N.J.)).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    72. Published

      Viral O-GalNAc peptide epitopes: a novel potential target in viral envelope glycoproteins

      Olofsson, S., Blixt, K. O., Bergström, T., Frank, M. & Wandall, Hans H., 2016, In: Reviews in Medical Virology. 26, 1, p. 34-48 15 p.

      Research output: Contribution to journalReviewResearchpeer-review

    73. Published

      Base Editor Correction of COL7A1 in Recessive Dystrophic Epidermolysis Bullosa Patient-Derived Fibroblasts and iPSCs

      Osborn, M. J., Newby, G. A., McElroy, A. N., Knipping, F., Nielsen, S. C., Riddle, M. J., Xia, L., Chen, W., Eide, C. R., Webber, B. R., Wandall, Hans H., Dabelsteen, Sally, Blazar, B. R., Liu, D. R. & Tolar, J., 2020, In: Journal of Investigative Dermatology. 140, 2, p. 338-347.e5

      Research output: Contribution to journalJournal articleResearchpeer-review

    74. Published

      Regulation of protein O-glycosylation in epithelial cells - the polypeptide GalNAc-transferases direct cellular differentiation and maintenance of tissue homeostasis

      Pallesen, E. M., Bagdonaite, Ieva , Vakhrushev, Sergey, Hansen, Lars, Joshi, Hiren Jitendra, Dabelsteen, Sally & Wandall, Hans H., Dec 2016, In: Glycobiology. 26, 12, p. 1391-1391

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    75. Published

      Wildtype p53-specific Antibody and T-Cell Responses in Cancer Patients

      Pedersen, Anders Elm, Stryhn, A., Justesen, S., Harndahl, M., Rasmussen, S., Donskov, F., Claesson, Mogens Helweg, Pedersen, J. W., Wandall, Hans H., Svane, Inge Marie & Buus, Søren, 2011, In: Journal of Immunotherapy. 34, 9, p. 629-40 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    76. Published

      Early detection of cancer in the general population: a blinded case-control study of p53 autoantibodies in colorectal cancer

      Pedersen, J. W., Gentry-Maharaj, A., Fourkala, E., Dawnay, A., Burnell, M., Zaikin, A., Pedersen, Anders Elm, Jacobs, I., Menon, U. & Wandall, Hans H., 15 Jan 2013, In: B J C. 108, 1, p. 107-114 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    77. Published

      Lectin Domains of Polypeptide GalNAc Transferases Exhibit Glycopeptide Binding Specificity

      Pedersen, J. W., Bennett, Eric Paul, Schjoldager, Katrine Ter-Borch Gram, Meldal, Morten Peter, Holmér, A. P., Blixt, O., Cló, E., Levery, S. B., Clausen, Henrik & Wandall, Hans H., 16 Sep 2011, In: The Journal of Biological Chemistry. 286, 37, p. 32684-96 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    78. Published

      Cancer-associated autoantibodies to MUC1 and MUC4--a blinded case–control study of colorectal cancer in UK collaborative trial of ovarian cancer screening

      Pedersen, J. W., Gentry-Maharaj, A., Nøstdal, A., Fourkala, E., Dawnay, A., Burnell, M., Zaikin, A., Burchell, J., Papadimitriou, J. T., Clausen, Henrik, Jacobs, I., Menon, U. & Wandall, Hans H., 1 May 2014, In: International Journal of Cancer. 134, 9, p. 2180-88 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    79. Published

      Seromic profiling of colorectal cancer patients with novel glycopeptide microarray

      Pedersen, J. W., Blixt, O., Bennett, Eric Paul, Tarp, M. A., Dar, I., Mandel, Ulla, Poulsen, Steen Seier, Pedersen, Anders Elm, Rasmussen, S., Jess, P., Clausen, Henrik & Wandall, Hans H., 15 Apr 2011, In: International Journal of Cancer. 128, 8, p. 1860-71 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    80. Published

      Multiplexed Detection of Autoantibodies to Glycopeptides Using Microarray

      Pedersen, J. W., Nøstdal, A. & Wandall, Hans H., 2019, Immunoproteomics: Methods and Protocols. Humana Press, p. 199-211 13 p. (Methods in Molecular Biology, Vol. 2024).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    81. Published

      Improved CRISPR/Cas9 gene editing by fluorescence activated cell sorting of green fluorescence protein tagged protoplasts

      Petersen, Bent L, Möller, S. R., Mravec, Jozef, Jørgensen, Bodil, Christensen, M., Liu, Y., Wandall, Hans H., Bennett, Eric Paul & Yang, Zhang, 2019, In: BMC Biotechnology. 19, p. 1-12 36.

      Research output: Contribution to journalJournal articleResearchpeer-review

    82. Published

      Immature truncated O-glycophenotype of cancer directly induces oncogenic features

      Radhakrishnan, P., Dabelsteen, S., Madsen, F. B., Francavilla, C., Kopp, K. L., Steentoft, C., Vakhrushev, S. Y., Olsen, J. V., Hansen, L., Bennett, E. P., Woetmann, A., Yin, G., Chen, L., Song, H., Bak, M., Hlady, R. A., Peters, S. L., Opavsky, R., Thode, C., Qvortrup, K. & 4 others, Schjoldager, Katrine Ter-Borch Gram, Clausen, Henrik, Hollingsworth, M. A. & Wandall, Hans H., 12 Aug 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 39, p. e4066-e4077 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    83. Published

      Carbon anhydrase IX specific immune responses in patients with metastatic renal cell carcinoma potentially cured by interleukin-2 based immunotherapy

      Rasmussen, S., Donskov, F., Pedersen, J. W., Wandall, Hans H., Buus, Søren, Harndahl, M., Braendstrup, P., Claesson, Mogens Helweg & Pedersen, Anders Elm, Aug 2013, In: Immunopharmacology and Immunotoxicology. 35, 4, p. 487-96 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    84. Published

      Aberrant expression of mucin core proteins and o-linked glycans associated with progression of pancreatic cancer

      Remmers, N., Anderson, J. M., Linde, E. M., DiMaio, D. J., Lazenby, A. J., Wandall, Hans H., Mandel, Ulla, Clausen, Henrik, Yu, F. & Hollingsworth, M. A., 15 Apr 2013, In: Clinical Cancer Research. 19, 8, p. 1981-93 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    85. Published

      Reduced ferritin levels in individuals with non-O blood group: Results from the Danish Blood Donor Study

      Rigas, A. S., Berkfors, A. A., Pedersen, Ole Birger Vesterager, Sørensen, E., Nielsen, K. R., Larsen, M. H., Paarup, H. M., Wandall, Hans H., Erikstrup, C., Hjalgrim, H. & Ullum, H., Dec 2017, In: Transfusion. 57, 12, p. 2914–2919

      Research output: Contribution to journalJournal articleResearchpeer-review

    86. Published

      Galectin-1 induces a tumor-associated macrophage phenotype and upregulates indoleamine 2,3-dioxygenase-1

      Levann, Asha Maria Rudjord, Ye, Z., Hafkenscheid, L., Horn, S., Wiegertjes, R., Nielsen, Mathias Alexander Ingemann, Song, Ming, Mathiesen, C. B. K., Stoop, J., Stowell, S., Straten, P. T., Leffler, H., Vakhrushev, Sergey, Dabelsteen, Sally, Olsen, Jesper Velgaard & Wandall, Hans H., 2023, In: iScience. 26, 7, 21 p., 106984.

      Research output: Contribution to journalJournal articleResearchpeer-review

    87. Published

      Microvesicle Cargo of Tumor-Associated MUC1 to Dendritic Cells Allows Cross-presentation and Specific Carbohydrate Processing

      Rughetti, A., Rahimi, H., Belleudi, F., Napoletano, C., Battisti, F., Zizzari, I. G., Antonilli, M., Bellati, F., Wandall, Hans H., Benedetti Panici, P., Burchell, J. M., Torrisi, M. R. & Nuti, M., Feb 2014, In: Cancer Immunology Research (CIR). 2, 2, p. 177-86 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    88. Published

      Dual roles for hepatic lectin receptors in the clearance of chilled platelets

      Rumjantseva, V., Grewal, P. K., Wandall, Hans H., Josefsson, E. C., Sørensen, A. L., Larson, G., Marth, J. D., Hartwig, J. H. & Hoffmeister, K. M., 2009, In: Nature Medicine. 15, 11, p. 1273-80 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    89. Published

      Localization of three human polypeptide GalNAc-transferases in HeLa cells suggests initiation of O-linked glycosylation throughout the Golgi apparatus.

      Röttger, S., White, J., Wandall, Hans H., Olivo, J. C., Stark, A., Bennett, Eric Paul, Whitehouse, C., Berger, E. G., Clausen, Henrik & Nilsson, T., 1998, In: Journal of Cell Science. 111 ( Pt 1), p. 45-60 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    90. Published

      Using a CRISPR-Cas Whole-Genome Screen to Identify Genetic Factors Linked to expression of Cancer-Associated O-glycans

      Rømer, T. B., Dylander, A., Horn, S., Pallesen, E. M. H. & Wandall, Hans H., 6 Nov 2018.

      Research output: Contribution to conferencePosterResearchpeer-review

    91. Published

      Mapping of truncated O-glycans in cancers of epithelial and non-epithelial origin

      Rømer, T. B., Aasted, Mikkel Koed Møller, Dabelsteen, Sally, Groen, A., Schnabel, J., Tan, E., Pedersen, J. W., Haue, Amalie Dahl & Wandall, Hans H., 2021, In: British Journal of Cancer. 125, 9, p. 1239-1250 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    92. Published

      CRISPR-screen identifies ZIP9 and dysregulated Zn2+ homeostasis as a cause of cancer-associated changes in glycosylation

      Rømer, T. B., Khoder-Agha, F., Aasted, Mikkel Koed Møller, de Haan, Noortje, Horn, S., Dylander, A., Zhang, T., Pallesen, E. M. H., Dabelsteen, S., Wuhrer, M., Høgsbro, Christine Flodgaard, Thomsen, E. A., Mikkelsen, J. G. & Wandall, Hans H., 2023, In: Glycobiology. 33, 9, p. 700-714 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    93. Published

      Truncated mucin type O-Glycans in Epithelial Cancers: Central Drivers or Blind Passengers?

      Rømer, T. B., Pallesen, E. M. H., Levann, Asha Maria Rudjord, Dylander, A. A. N., Haue, Amalie Dahl, Li, Minyan, Dabelsteen, Sally & Wandall, Hans H., 28 Aug 2018.

      Research output: Contribution to conferencePosterResearchpeer-review

    94. Published

      MUC4 enhances gemcitabine resistance and malignant behaviour in pancreatic cancer cells expressing cancer-associated short O-glycans

      Sagar, S., Leiphrakpam, P. D., Thomas, D., McAndrews, K. L., Caffrey, T. C., Swanson, B. J., Clausen, Henrik, Wandall, Hans H., Hollingsworth, M. A. & Radhakrishnan, P., 2021, In: Cancer Letters. 503, p. 91-102 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    95. Published

      Deconstruction of O-glycosylation-GalNAc-T isoforms direct distinct subsets of the O-glycoproteome

      Schjoldager, Katrine Ter-Borch Gram, Joshi, Hiren Jitendra, Kong, Y., Goth, C. K., King-Smith, S. L., Wandall, Hans H., Bennett, Eric Paul, Vakhrushev, Sergey & Clausen, Henrik, Dec 2015, In: E M B O Reports. 16, 12, p. 1713-22 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    96. Published

      Probing isoform-specific functions of polypeptide GalNAc-transferases using zinc finger nuclease glycoengineered SimpleCells

      Schjoldager, Katrine Ter-Borch Gram, Vakhrushev, Sergey, Kong, Y., Steentoft, C., Nudelman, A. S., Pedersen, N. B., Wandall, Hans H., Mandel, Ulla, Bennett, Eric Paul, Levery, S. B. & Clausen, Henrik, Jun 2012, In: Proceedings of the National Academy of Sciences USA (PNAS). 109, 25, p. 9893-8 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    97. Published

      The Drosophila gene brainiac encodes a glycosyltransferase putatively involved in glycosphingolipid synthesis.

      Schwientek, T., Keck, B., Levery, S. B., Jensen, M. A., Pedersen, J. W., Wandall, Hans H., Stroud, M., Cohen, S. M., Amado, M. & Clausen, Henrik, 2002, In: Journal of Biological Chemistry. 277, 36, p. 32421-9 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    98. Published

      Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology

      Steentoft, C., Vakhrushev, Sergey, Joshi, Hiren Jitendra, Kong, Y., Vester-Christensen, M. B., Schjoldager, Katrine Ter-Borch Gram, Lavrsen, K., Dabelsteen, Sally, Pedersen, N. B., da Silva, L. P. M., Gupta, R., Bennett, Eric Paul, Mandel, Ulla, Brunak, Søren, Wandall, Hans H., Levery, S. B. & Clausen, Henrik, 15 May 2013, In: E M B O Journal. 32, 10, p. 1478-1488 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    99. Published

      Precision genome editing: A small revolution for glycobiology

      Steentoft, C., Bennett, Eric Paul, Schjoldager, Katrine Ter-Borch Gram, Vakhrushev, Sergey, Wandall, Hans H. & Clausen, Henrik, Aug 2014, In: Glycobiology. 24, 8, p. 663-80 18 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    100. Published

      Mining the O-glycoproteome using zinc-finger nuclease-glycoengineered SimpleCell lines

      Steentoft, C., Vakhrushev, Sergey, Vester-Christensen, M. B., Schjoldager, Katrine Ter-Borch Gram, Kong, Y., Bennett, Eric Paul, Mandel, Ulla, Wandall, Hans H., Levery, S. B. & Clausen, Henrik, Oct 2011, In: Nature Methods. 8, 11, p. 977-82 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

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