Jesper Velgaard Olsen
Professor, Deputy Head of Centre, Professor
Jesper Olsen studied analytical chemistry in the group of Roman Zubarev at the University of Southern Denmark in Odense, and obtained his PhD in biochemistry and molecular biology in the laboratory of Matthias Mann. During his PhD he was involved in developing high-resolution mass spectrometry-based proteomics. He spent 4 years as a post-doctoral fellow at the Max Planck Institute for Biochemistry in Munich, where he developed a quantitative phosphoproteomics technology that was applied to global time-resolved analyses of cell signaling pathways in human cells. In 2009, Jesper was recruited back to Denmark to head a group at the newly established Novo Nordisk Foundation Center for Protein Research (CPR) at University of Copenhagen. In 2012, he was promoted to vice director of CPR and in 2014 full professor. Jesper has received a number of research awards including the Max Planck Institute for Biochemistry Junior Research Award and HUPO Young Investigator Award in Proteomic Sciences.
Selected publications
- Published
Rapid and site-specific deep phosphoproteome profiling by data-independent acquisition without the need for spectral libraries
Bekker-Jensen, D. B., Bernhardt, O. M., Hogrebe, A., Martinez Del Val, Ana, Verbeke, L., Gandhi, T., Kelstrup, C. D., Reiter, L. & Olsen, Jesper Velgaard, 2020, In: Nature Communications. 11, 1, 12 p., 787.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
Lundby, Alicia, Franciosa, Giulia, Emdal, Kristina Bennet, Refsgaard, J. C., Gnosa, S. P., Bekker-Jensen, D. B., Secher, A., Maurya, S. R., Paul, I., Mendez, B. L., Kelstrup, C. D., Francavilla, C., Kveiborg, Marie, Montoya, Guillermo, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2019, In: Cell. 179, 2, p. 543-560Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early Pleistocene enamel proteome from Dmanisi resolves Stephanorhinus phylogeny
Cappellini, E., Welker, F., Pandolfi, L., Ramos-Madrigal, J., Samodova, D., Rüther, P. L., Fotakis, A. K., Lyon, D., Moreno-Mayar, J. V., Bukhsianidze, M., Rakownikow Jersie-Christensen, R., Mackie, M., Ginolhac, A., Ferring, R., Tappen, M., Palkopoulou, E., Dickinson, M. R., Stafford, T. W., Chan, Y. L., Götherström, A. & 23 others, , 2019, In: Nature. 574, 7776, p. 103-107Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates
Jakobsson, M. E., Małecki, J. M., Halabelian, L., Nilges, B. S., Pinto, R., Kudithipudi, S., Munk, S., Davydova, E., Zuhairi, F. R., Arrowsmith, C. H., Jeltsch, A., Leidel, S. A., Olsen, Jesper Velgaard & Falnes, P. Ø., 2018, In: Nature Communications. 9, 1, 3411.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-Scale Phosphoproteomics Reveals Shp-2 Phosphatase-Dependent Regulators of Pdgf Receptor Signaling
Batth, Tanveer Singh, Papetti, M., Pfeiffer, A., Tollenaere, M. A. X., Francavilla, C. & Olsen, Jesper Velgaard, 2018, In: Cell Reports. 22, 10, p. 2784-2796 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrated proximal proteomics reveals IRS2 as a determinant of cell survival in ALK-driven neuroblastoma
Emdal, Kristina Bennet, Pedersen, A., Bekker-Jensen, D. B., Lundby, Alicia, Claeys, S., De Preter, K., Speleman, F., Francavilla, C. & Olsen, Jesper Velgaard, 20 Nov 2018, In: Science Signaling. 11, 557, p. 1-17 17 p., eaap9752.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative metaproteomics of medieval dental calculus reveals individual oral health status
Jersie-Christensen, R. R., Lanigan, Liam Thomas, Lyon, D., Mackie, Meaghan, Midjord-Belstrøm, Daniel, Kelstrup, C. D., Fotaki, Anna Katerina, Willerslev, Eske, Lynnerup, Niels, Jensen, Lars Juhl, Cappellini, Enrico & Olsen, Jesper Velgaard, 2018, In: Nature Communications. 9, p. 1-12 4744.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Benchmarking common quantification strategies for large-scale phosphoproteomics
Hogrebe, A., von Stechow, L., Bekker-Jensen, D. B., Weinert, B. T., Kelstrup, C. D. & Olsen, Jesper Velgaard, 2018, In: Nature Communications. 9, 1, p. 1-13 1045.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes
Bekker-Jensen, D. B., Kelstrup, C. D., Batth, Tanveer Singh, Buch-Larsen, Sara Charlotte, Haldrup, C., Bramsen, J. B., Sørensen, K. D., Høyer, S., Ørntoft, T. F., Andersen, C. L., Nielsen, Michael Lund & Olsen, Jesper Velgaard, 2017, In: Cell Systems. 4, 6, p. 587-599, e1-e4 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking
Francavilla, C., Papetti, M., Rigbolt, K. T. G., Pedersen, A., Sigurdsson, J. O., Cazzamali, G., Karemore, G., Blagoev, B. & Olsen, Jesper Velgaard, Jun 2016, In: Nature Structural and Molecular Biology. 23, 6, p. 608–618 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analytic framework for peptidomics applied to large-scale neuropeptide identification
Secher, A., Kelstrup, C. D., Conde-Frieboes, K. W., Pyke, C., Raun, K., Wulff, B. S. & Olsen, Jesper Velgaard, 2016, In: Nature Communications. 7, 10 p., 11436.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid and Deep Proteomes by Faster Sequencing on a Benchtop Quadrupole Ultra-High-Field Orbitrap Mass Spectrometer
Kelstrup, C. D., Jersie-Christensen, R. R., Batth, Tanveer Singh, Arrey, T. N., Kuehn, A., Kellmann, M. & Olsen, Jesper Velgaard, 28 Oct 2014, In: Journal of Proteome Research. 13, 12, p. 6187-95 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics
Lundby, A., Rossin, E. J., Steffensen, A. B., Acha, M. R., Newton-Cheh, C., Pfeufer, A., Lynch, S. N., Olesen, S-P., Brunak, S., Ellinor, P. T., Jukema, J. W., Trompet, S., Ford, I., Macfarlane, P. W., Krijthe, B. P., Hofman, A., Uitterlinden, A. G., Stricker, B. H., Nathoe, H. M., Spiering, W. & 8 others, , 22 Jun 2014, In: Nature Methods. 11, 8, p. 868-874 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional Proteomics Defines the Molecular Switch Underlying FGF Receptor Trafficking and Cellular Outputs
Francavilla, C., Rigbolt, K. T. G., Emdal, Kristina Bennet, Carraro, G., Vernet, E., Bekker-Jensen, D. B., Streicher, W., Wikström, M., Sundström, M., Bellusci, S., Cavallaro, U., Blagoev, B. & Olsen, Jesper Velgaard, 26 Sep 2013, In: Molecular Cell. 51, 6, p. 707-22 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Optimized Fast and Sensitive Acquisition Methods for Shotgun Proteomics on a Quadrupole Orbitrap Mass Spectrometer
Kelstrup, C. D., Young, C., Lavallee, R., Nielsen, Michael Lund & Olsen, Jesper Velgaard, 2012, In: Journal of Proteome Research. p. 3487-3497 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 9925376
Most downloads
-
1553
downloads
Molecular basis of Tousled-Like Kinase 2 activation
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
479
downloads
52 Genetic Loci Influencing Myocardial Mass
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
450
downloads
Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
Research output: Contribution to journal › Journal article › Research › peer-review
Published