Søren Skov

Søren Skov

Professor


  1. 2024
  2. Published

    Induction of CD8+ immune memory and enhanced inflammation in a skin inflammation model through pre-immunization with inactivated pathogens

    Falkenberg, C., Bartholdy, C., Koch, J., Toft, M., Skov, Søren, Hansen, Camilla Hartmann Friis & Hansen, Axel Kornerup, 2024, In: Clinical and Translational Science. 17, 1, 14 p., e13697.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2023
  4. Published

    Clinical Staphylococcus aureus inhibits human T-cell activity through interaction with the PD-1 receptor

    Mellergaard, M., Skovbakke, S. L., Jepsen, S. D., Panagiotopoulou, N., Hansen, A. B. R., Tian, W., Lund, A., Høgh, R. I., Møller, S. H., Guérillot, R., Hayes, A. S., Erikstrup, L. T., Andresen, L., Peleg, A. Y., Larsen, A. R., Stinear, T. P., Handberg, A., Erikstrup, C., Howden, B. P., Goletz, S. & 2 others, Frees, Dorte & Skov, Søren, 2023, In: mBio. 14, 5, 21 p., e01349-23.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Effect of Systemic Administration of CD4+ T cells and Local Administration of T-cell Stimulants on T-cell Activity in Psoriatic Skin Xenografts on NOG Mice

    Christensen, P. K., Hansen, Axel Kornerup, Skov, Søren, Larsen, J., Høyer-Hansen, M. H. & Koch, J., 2023, In: Comparative Medicine. 73, 4, p. 285-293 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Imiquimod induces skin inflammation in humanized BRGSF mice with limited human immune cell activity

    Christensen, P. K. F., Hansen, Axel Kornerup, Skov, Søren, Martel, B. C., Larsen, J., Høyer-Hansen, M. H. & Koch, J., 2023, In: PLoS ONE. 18, e0281005.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Sustaining the T-cell activity in xenografted psoriasis skin

    Christensen, P. K. F., Hansen, Axel Kornerup, Skov, Søren, Engkilde, K., Larsen, J., Høyer-Hansen, M. H. & Koch, J., 2023, In: PLoS ONE. 18, e0278390.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2022
  9. Published

    A porcine model of subcutaneous Staphylococcus aureus infection: a pilot study

    Nielsen, O. L., Mellergaard, M., Frees, Dorte, Larsen, M. N., Skov, Søren, Olsen, Lisbeth Høier & Reimann, Maria Josefine, 2022, In: APMIS - Journal of Pathology, Microbiology and Immunology. 130, 7, p. 359-370

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    CTLA4-Ig prevents development of neutralizing antibody formation after continuous treatment with human FVIII in HA rats

    Øvlisen, Gabi Overgaard, Thygesen, P., Weldingh, K. N., Bloem, E., Skov, Søren, Almholt, K., Lövgren, K. M., Ley, C. D. & Holm, T. L., 2022, In: Haemophilia. 28, 4, p. 568-577

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Effect of gluten-free diet and antibiotics on murine gut microbiota and immune response to tetanus vaccination

    Kihl, Pernille, Krych, Lukasz, Deng, Ling, Hansen, Lars Hestbjerg, Buschard, K., Skov, Søren, Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2022, In: Plos One. 17, 4, 21 p., e0266719.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Pre-immunization with inactivated pathogens recapitulates adult human immune traits in laboratory mice

    Falkenberg, C., Toft, M. F., Skov, Søren & Hansen, Axel Kornerup, 2022, In: Laboratory Animals. 56, S1, p. 25-25 S2A5.3.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  13. 2021
  14. Published

    Evaluation of Fluorescent Light Energy for the Treatment of Acute Second-degree Burns

    Mellergaard, M., Fauverghe, S., Scarpa, C., Pozner, V. L., Skov, Søren, Hebert, L., Nielsen, M., Bassetto, F. & Téot, L., 2021, In: Military Medicine. 186, Suppl 1, p. 416-423 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Monocyte infiltration and differentiation in 3d multicellular spheroid cancer models

    Madsen, N. H., Nielsen, B. S., Nhat, S. L., Skov, Søren, Gad, M. & Larsen, J., 2021, In: Pathogens. 10, 8, 969.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2020
  17. Published

    Staphylococcus aureus induces cell-surface expression of immune stimulatory NKG2D ligands on human monocytes

    Mellergaard, M., Høgh, R. I., Feilberg, Astrid Lund, Aldana, Blanca, Guérillot, R., Møller, S. H., Hayes, A. S., Panagiotopoulou, N., Frimand, Z., Jepsen, Stine Dam, Hansen, Camilla Hartmann Friis, Andresen, Lars, Larsen, A. R., Peleg, A. Y., Stinear, T. P., Howden, B. P., Waagepetersen, Helle S., Frees, Dorte & Skov, Søren, 2020, In: The Journal of Biological Chemistry. 295, p. 11803-11821

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells

    Møller, S. H., Mellergaard, M., Madsen, M., Bermejo, A. V., Jepsen, Stine Dam, Hansen, M. H., Høgh, R. I., Aldana, Blanca, Desler, Claus, Rasmussen, Lene Juel, Sustarsic, E. G., Gerhart-Hines, Zach, Daskalaki, E., Wheelock, C. E., Hiron, T. K., Lin, D., O'Callaghan, C. A., Wandall, Hans H., Andresen, Lars & Skov, Søren, 2020, In: Frontiers in Immunology. 11, 22 p., 1968.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Dynamics and Outcome of Macrophage Interaction Between Salmonella Gallinarum, Salmonella Typhimurium, and Salmonella Dublin and Macrophages From Chicken and Cattle

    Huang, K., Fresno, A. H., Skov, Søren & Olsen, John Elmerdahl, 2020, In: Frontiers in Cellular and Infection Microbiology. 9, 12 p., 420.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Fluorescent light energy in wound healing: When is a photon something more?

    Zago, M., Dehghani, M., Jaworska, J., Mellergaard, M., Edge, D., Corell, D. D., Campbell, S. E., Skov, Søren, Hebert, L., Nielsen, M. & Hamblin, M., 2020, Mechanisms of Photobiomodulation Therapy XV. Hamblin, M. R., Carroll, J. D. & Arany, P. (eds.). SPIE - International Society for Optical Engineering, 9 p. 112210A. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol. 11221).

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  21. Published

    Fumarate Upregulates Surface Expression of ULBP2/ULBP5 by Scavenging Glutathione Antioxidant Capacity

    Høgh, R. I., Droujinine, A., Møller, S. H., Jepsen, Stine Dam, Mellergaard, M., Andresen, Lars & Skov, Søren, 2020, In: The Journal of Immunology. 204, 7, p. 1746-1759 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Metabolism of short-chain fatty acid propionate induces surface expression of NKG2D ligands on cancer cells

    Høgh, R. I., Møller, S. H., Jepsen, Stine Dam, Mellergaard, M., Feilberg, Astrid Lund, Pejtersen, M., Fitzner, E., Andresen, Lars & Skov, Søren, 2020, In: FASEB Journal. 34, 11, p. 15531-15546

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    TL1A regulates adipose-resident innate lymphoid immune responses and enables diet-induced obesity in mice

    Tougaard, P., Martinsen, L. O., Lützhøft, Ditte Olsen, Jensen, Henrik Elvang, Flethøj, M., Vandenabeele, P., Pedersen, Anders Elm, Skov, Søren, Hansen, Axel Kornerup & Hansen, Camilla Hartmann Friis, 2020, In: International journal of obesity (2005). 44, p. 1062–1074

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2019
  25. In-vitro and in-vivo evaluation of a novel bioprosthetic pulmonary valve for use in congenital heart surgery

    Rasmussen, J., Skov, Søren, Nielsen, D. B., Jensen, I. L., Tjørnild, M. J., Johansen, P. & Hjortdal, Vibeke Elisabeth, 9 Jan 2019, In: Journal of Cardiothoracic Surgery. 14, 1, p. 6

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Interaction differences of the avian host-specific salmonella enterica serovar gallinarum, the host-generalist S. Typhimurium, and the cattle host-adapted S. Dublin with chicken primary macrophage

    Huang, K., Herrero-Fresno, A., Thoefner, Ida , Skov, Søren & Olsen, John Elmerdahl, 2019, In: Infection and Immunity. 87, 12, e00552-19.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    TL1A Aggravates Cytokine-Induced Acute Gut Inflammation and Potentiates Infiltration of Intraepithelial Natural Killer Cells in Mice

    Tougaard, P., Martinsen, L. O., Zachariassen, L. F., Krych, Lukasz, Nielsen, Dennis Sandris, Buus, Terkild Brink, Pedersen, Anders Elm, Hansen, Axel Kornerup, Skov, Søren & Hansen, Camilla Hartmann Friis, 2019, In: Inflammatory Bowel Diseases. 25, 3, p. 510-523

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2018
  29. Published

    Ascaris suum infection down-regulates inflammatory pathways in the pig intestine in vivo and in human dendritic cells in vitro

    Midttun, H. L. E., Acevedo, N., Skallerup, P., Almeida, Sara dos Santos, Skovgaard, K., Andresen, Lars, Skov, Søren, Caraballo, L., van Die, I., Jørgensen, Claus Bøttcher, Fredholm, Merete, Thamsborg, Stig Milan, Nejsum, P. & Williams, Andrew Richard, 2018, In: The Journal of Infectious Diseases. 217, 2, p. 310-319

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Human P2Y11 expression level affects human P2X7 receptor-mediated cell death

    Dreisig, K., Sund, L., Dommer, M. W., Kristensen, N. P., Boddum, K., Viste, R., Fredholm, S., Ødum, Niels, Jäättelä, M., Skov, Søren & Kornum, Birgitte Rahbek, 2018, In: Frontiers in Immunology. 9, JUN, 12 p., 1159.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2017
  32. Published

    Acute Haemarthrosis in the Haemophilia A Rat Generates a Local and Systemic Proinflammatory Response

    Lovgren, K. M., Christensen, K. R., Majewski, W., Ostrup, O., Skov, Søren & Wiinberg, B., Nov 2017, In: Thrombosis and Haemostasis. 117, 11, p. 2092-2104

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    A porcine subcutaneous Staphylococcus aureus abscess model - a pilot study

    Nielsen, O. L., Larsen, M. N., Frees, Dorte, Pedersen, M. M., Skov, Søren & Olsen, Lisbeth Høier, 2017.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  34. Published

    Co-operative suppression of inflammatory responses in human dendritic cells by plant proanthocyanidins and products from the parasitic nematode Trichuris suis

    Williams, Andrew Richard, Klaver, E. J., Laan, L. C., Ramsay, A., Fryganas, C., Difborg, R., Kringel, H., Reed, J. D., Mueller-Harvey, I., Skov, Søren, van Die, I. & Thamsborg, Stig Milan, 2017, In: Immunology. 150, 3, p. 312-328 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    The effect of oral administration of antibiotics on Schistosoma mansoni egg-induced pathology in mouse models

    Kildemoes, A. O., Schramm, G., Pakkenberg, B., Hansen, Axel Kornerup, Skov, Søren, Nielsen, Dennis Sandris & Vennervald, Birgitte J, 2017, In: Tropical Medicine & International Health. 22, S1, p. 12-13 2 p., 1S6.3.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  36. Published

    The gastrointestinal tract of farmed mink (Neovison vison ) maintains a diverse mucosa-associated microbiota following a 3-day fasting period.

    Bahl, M. I., Hammer, Anne Sofie Vedsted, Clausen, T. N., Jakobsen, A. L., Skov, Søren & Andresen, Lars, 2017, In: MicrobiologyOpen. 6, 3, 8 p., e00434.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. 2016
  38. Published

    Joint bleeds increase the inhibitor response to human factor VIII in a rat model of severe haemophilia A

    Löfgren, Karin Maria, Søndergaard, H., Skov, Søren & Wiinberg, B., Sep 2016, In: Haemophilia. 22, 5, p. 772-779 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Non-genetic risk factors in haemophilia A inhibitor management: the danger theory and the use of animal models

    Löfgren, Karin Maria, Søndergaard, H., Skov, Søren & Wiinberg, B., Sep 2016, In: Haemophilia. 22, 5, p. 657-666 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  40. Published

    Distinct molecular signatures of mild extrinsic and intrinsic atopic dermatitis

    Martel, B. C., Litman, Thomas, Hald, A., Norsgaard, H., Lovato, P., Dyring-Andersen, Beatrice, Skov, Lone, Thestrup-Pedersen, K., Skov, Søren, Skak, K. & Poulsen, Lars K., Jun 2016, In: Experimental Dermatology Online. 25, 6, p. 453-459 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Antibody response to recombinant human coagulation factor VIII in a new rat model of severe hemophilia A

    Löfgren, Karin Maria, Sondergaard, H., Skov, Søren, Weldingh, K. N., Tranholm, M. & Wiinberg, B., Apr 2016, In: Journal of Thrombosis and Haemostasis. 14, 4, p. 747-756

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Different cytokine profiles of skin-derived T cell cultures from patients with atopic dermatitis and psoriasis

    Martel, B. C., Dyring-Andersen, Beatrice, Skov, Lone, Thestrup-Pedersen, K., Skov, Søren, Skak, K. & Poulsen, Lars K., Apr 2016, In: Inflammation Research. 65, 4, p. 265-72 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Biologics beyond TNF-α inhibitors and the effect of targeting the homologues TL1A-DR3 pathway in chronic inflammatory disorders

    Tougaard, P., Zervides, K. A., Skov, Søren, Hansen, Axel Kornerup & Pedersen, Anders Elm, Feb 2016, In: Immunopharmacology and Immunotoxicology. 38, 1, p. 29-38 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  44. Published

    Anti-RANKL treatment inhibits erosive joint destruction and lowers inflammation but has no effect on bone formation in the delayed-type hypersensitivity arthritis (DTHA) model

    Atkinson, S. M., Bleil, J., Maier, R., Kuehl, A. A., Thorn, M., Serikawa, K., Fox, B., Kruse, K., Haase, C., Skov, Søren, Nansen, A. & Syrbe, U., 23 Jan 2016, In: Arthritis Research & Therapy. 18, 12 p., 28.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Depletion of regulatory T cells leads to an exacerbation of delayedtype hypersensitivity arthritis in C57BL/6 mice that can be counteracted by IL-17 blockade

    Atkinson, S. M., Hoffmann, U., Bach, E., Danneskiold-Samsøe, Niels Banhos, Kristiansen, Karsten, Serikawa, K., Fox, B., Kruse, K., Haase, C., Skov, Søren & Nansen, A., 2016, In: Disease Models & Mechanisms. 9, p. 427-440 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Polymerization-dependent activation of porcine γδ T-cells by proanthocyanidins

    Williams, Andrew Richard, Fryganas, C., Reichwald, K., Skov, Søren, Mueller-Harvey, I. & Thamsborg, Stig Milan, 2016, In: Research in Veterinary Science. 105, p. 209-215 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. 2015
  48. Published

    Stepwise decrease in daptomycin susceptibility in clinical Staphylococcus aureus isolates associated with an initial mutation in rpoB and a compensatory inactivation of the clpX gene

    Bæk, K. T., Thøgersen, L., Mogensen, R. G., Pedersen, M. M., Thomsen, Line Elnif, Petersen, A., Skov, Søren, Cameron, D. R., Peleg, A. Y. & Frees, Dorte, Nov 2015, In: Antimicrobial Agents and Chemotherapy. 59, 11, p. 6983-6991 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Treatment with anti-C5aR mAb leads to early-onset clinical and mechanistic effects in the murine delayed-type hypersensitivity arthritis model

    Atkinson, S. M., Nansen, A., Usher, P. A., Sondergaard, B., Mackay, C. R., Friedrichsen, B., Chang, C., Tang, R., Skov, Søren, Haase, C. & Hornum, L., Nov 2015, In: Autoimmunity. 48, 7, p. 460-470 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Secretion, blood levels and cutaneous expression of TL1A in psoriasis patients

    Pedersen, Anders Elm, Schmidt, E. G. W., Sørensen, J. F., Faber, Carsten, Nielsen, B. S., Holmstrøm, K., Omland, S. H., Tougaard, P., Skov, Søren & Bang, B., Jul 2015, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 123, 7, p. 547-555 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Advanced imaging techniques show progressive arthropathy following experimentally induced knee bleeding in a factor VIII-/- rat model

    Sorensen, K. R., Roepstorff, K., Petersen, M., Wiinberg, B., Hansen, Axel Kornerup, Skov, Søren & Nielsen, Lise Nikolic, Jun 2015, In: Journal of Thrombosis and Haemostasis. 13, S2, p. 107-107

    Research output: Contribution to journalConference abstract in journalResearch

  52. Published

    Human atopic dermatitis skin-derived T cells can induce a reaction in mouse keratinocytes in vivo

    Martel, B. C., Blom, L., Dyring-Andersen, Beatrice, Skov, Lone, Thestrup-Pedersen, K., Skov, Søren, Skak, K. & Poulsen, Lars K., 22 May 2015, In: Scandinavian Journal of Immunology. 82, 2, p. 125–134 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    A conserved WW domain-like motif regulates invariant chain-dependent cell-surface transport of the NKG2D ligand ULBP2

    Uhlenbrock, F. K., van Andel, E., Andresen, Lars & Skov, Søren, 18 May 2015, In: Molecular Immunology. 66, p. 418-427 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Differential serodiagnostics of Toxocara canis and Toxocara cati - is it possible?

    Poulsen, C. S., Skov, Søren, Yoshida, A., Skallerup, P., Maruyama, H., Thamsborg, Stig Milan & Nejsum, P., Apr 2015, In: Parasite Immunology. 37, 4, p. 204-207 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Depletion of regulatory T cells in a hapten-induced inflammation model results in prolonged and increased inflammation driven by T cells

    Christensen, A. D., Skov, Søren, Kvist, P. H. & Haase, C., Mar 2015, In: Clinical and Experimental Immunology. 179, 3, p. 485-499 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    TL1A regulates TCRγδ+ intraepithelial lymphocytes and gut microbial composition

    Tougaard, P., Skov, Søren, Pedersen, Anders Elm, Krych, Lukasz, Nielsen, Dennis Sandris, Bahl, M. I., Christensen, E. G., Licht, T. R., Poulsen, Steen Seier, Metzdorff, S. B., Hansen, Axel Kornerup & Hansen, Camilla Hartmann Friis, 2015, In: European Journal of Immunology. 45, 3, p. 865-875 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. 2014
  58. Published

    Steps in unraveling the mystery of chronic inflammation: TL1A

    Reichwald, K. & Skov, Søren, 1 Jan 2014, In: International Journal of Clinical Rheumatology. 9, 3, p. 233-235 3 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  59. Published

    N-glycosylation of asparagine 8 regulates surface expression of major histocompatibility complex class I chain-related protein A (MICA) alleles dependent on threonine 24

    Pedersen, M. M., Skovbakke, S. L., Schneider, C. L., Lauridsen, F. K. B., Andresen, Lars, Jensen, H. & Skov, Søren, 2014, In: Journal of Biological Chemistry. 289, 29, p. 20078-20091 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    A maternal gluten-free diet reduces inflammation and diabetes incidence in the offspring of NOD mice

    Hansen, Camilla Hartmann Friis, Krych, Lukasz, Buschard, K., Metzdorff, S. B., Nellemann, C. L., Hansen, Lars Hestbjerg, Nielsen, Dennis Sandris, Frøkiær, Hanne, Skov, Søren & Hansen, Axel Kornerup, 2014, In: Diabetes. 63, 8, p. 2821-2832 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Mode of delivery shapes gut colonization pattern and modulates regulatory immunity in mice

    Hansen, Camilla Hartmann Friis, Andersen, L. S. F., Krych, Lukasz, Metzdorff, S. B., Hasselby, Jane Preuss, Skov, Søren, Nielsen, Dennis Sandris, Buschard, K., Hansen, Lars Hestbjerg & Hansen, Axel Kornerup, 2014, In: Journal of Immunology. 193, 3, p. 1213-1222 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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