Ole Haagen Nielsen
Clinical Professor
Department of Clinical Medicine
Borgmester Ib Juuls Vej 1, 2730 Herlev
Denmark
Member of:
Internal Medicine: Gastroenterology and Hepatology
- 2024
- Published
Updates on the management of inflammatory bowel disease from periconception to pregnancy and lactation
Nielsen, Ole Haagen, Gubatan, J. M., Kolho, K., Streett, S. E. & Maxwell, C., 30 Mar 2024, In: The Lancet. 403, 10433, p. 1291-1303Research output: Contribution to journal › Review › Research › peer-review
- Published
Immune cell-derived signals governing epithelial phenotypes in homeostasis and inflammation
Hausmann, Annika, Steenholdt, Casper, Nielsen, Ole Haagen & Jensen, Kim Bak, 20 Mar 2024, In: Trends in Molecular Medicine. 30, 3, p. 239-251Research output: Contribution to journal › Review › Research › peer-review
- Published
Diagnosis and Pharmacological Management of Microscopic Colitis in Geriatric Care
Nielsen, Ole Haagen & Pardi, D. S., 2024, In: Drugs and Aging. 41, p. 113-123 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Gut Microbiome and Disorders of the Gastrointestinal Tract
Hammerhøj, A., Gubatan, J. M. & Nielsen, Ole Haagen, 2024, In: Microorganisms. 12, 3, 2 p., 576.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
IAPs and RIPK1 mediate LPS-induced cytokine production in healthy subjects and Crohn's disease
Seidelin, Jakob Benedict, Jensen, Simone, Hansen, M., Bronze, M. R. D. C., Cuchet-Lourenҫo, D., Nejentsev, S., LaCasse, E. C. & Nielsen, Ole Haagen, 2024, In: Clinical and Experimental Immunology. 215, 3, p. 291–301 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mirikizumab (Omvoh™) for ulcerative colitis
Hammerhøj, A., Boye, T. L., Langholz, Ebbe & Nielsen, Ole Haagen, 2024, In: Trends in Pharmacological Sciences. 45, 3, p. 281-282 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Kinase Signaling in Colitis-Associated Colon Cancer and Inflammatory Bowel Disease
Temby, M., Boye, T. L., Hoang, J., Nielsen, Ole Haagen & Gubatan, J., Nov 2023, In: Biomolecules. 13, 11, 14 p., 1620.Research output: Contribution to journal › Review › Research › peer-review
- Published
Comparative onset of effect of biologics and small molecules in moderate-to-severe ulcerative colitis: a systematic review and network meta-analysis
Attauabi, M., Dahl, E. K., Burisch, J., Gubatan, J., Nielsen, Ole Haagen & Seidelin, Jakob Benedict, 2023, In: EClinicalMedicine. 57, 3, 101866.Research output: Contribution to journal › Review › Research › peer-review
- Published
Deucravacitinib (Sotyktu™) for plaque psoriasis
Granau, Agnete Marie, Boye, T. L., Jensen, Kim Bak & Nielsen, Ole Haagen, 2023, In: Trends in Pharmacological Sciences. 44, 4, p. 252-253Research output: Contribution to journal › Letter › Research › peer-review
- Published
Effectiveness of Non-Budesonide Therapies in Management of Microscopic Colitis: A Systematic Review and Meta-analysis
Rehde, A., Hendel, S. K., Juhl, C. B., Gubatan, J. & Nielsen, Ole Haagen, 2023, In: Drugs. 83, 11, p. 1027-1038 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigating the Crime Scene—Molecular Signatures in Inflammatory Bowel Disease
Andersen, V., Bennike, T. B., Bang, C., Rioux, J. D., Hébert-Milette, I., Sato, T., Hansen, Axel Kornerup & Nielsen, Ole Haagen, 2023, In: International Journal of Molecular Sciences. 24, 13, 11217.Research output: Contribution to journal › Review › Research › peer-review
- Published
Paternal Medications in Inflammatory Bowel Disease and Male Fertility and Reproductive Outcomes: A Systematic Review and Meta-analysis
Gubatan, J., Barber, G. E., Nielsen, Ole Haagen, Juhl, C. B., Maxwell, C., Eisenberg, M. L. & Streett, S. E., 2023, In: Clinical Gastroenterology and Hepatology. 21, 9, p. 2222-2238 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Selective JAK1 inhibitors for the treatment of inflammatory bowel disease
Nielsen, Ole Haagen, Boye, T. L., Gubatan, J., Chakravarti, D., Jaquith, J. B. & LaCasse, E. C., 2023, In: Pharmacology and Therapeutics. 245, 108402.Research output: Contribution to journal › Review › Research › peer-review
- 2022
- Published
Microscopic colitis: Etiopathology, diagnosis, and rational management
Nielsen, Ole Haagen, Fernandez-Banares, F., Sato, T. & Pardi, D. S., 1 Aug 2022, In: eLife. 11, 21 p., e79397.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biologics for Inflammatory Bowel Disease and their Safety in Pregnancy: A Systematic Review and Meta-analysis
Nielsen, Ole Haagen, Gubatan, J. M., Juhl, C. B., Streett, S. E. & Maxwell, C., 2022, In: Clinical Gastroenterology and Hepatology. 20, 1, p. 74-87.e3Research output: Contribution to journal › Journal article › Research › peer-review
- Published
COLAR: open-label clinical study of IL-6 blockade with tocilizumab for the treatment of immune checkpoint inhibitor-induced colitis and arthritis
Holmstroem, R. B., Nielsen, Ole Haagen, Jacobsen, Søren, Riis, Lene Buhl, Theile, S., Bjerrum, Jakob Tveiten , Vilmann, Peter, Johansen, Julia Sidenius, Boisen, M. K., Eefsen, R. H. L., Svane, Inge Marie, Nielsen, Dorte Lisbet & Chen, I. M., 2022, In: Journal for ImmunoTherapy of Cancer. 10, 9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gut Microbiome in Inflammatory Bowel Disease: Role in Pathogenesis, Dietary Modulation, and Colitis-Associated Colon Cancer
Gubatan, J., Boye, T. L., Temby, M., Sojwal, R. S., Holman, D. R., Sinha, S. R., Rogalla, S. R. & Nielsen, Ole Haagen, 2022, In: Microorganisms. 10, 7, 1371.Research output: Contribution to journal › Review › Research › peer-review
- Published
Impact of fibre and red/processed meat intake on treatment outcomes among patients with chronic inflammatory diseases initiating biological therapy: A prospective cohort study
Overgaard, S. H., Sørensen, S. B., Munk, H. L., Nexøe, A. B., Glerup, H., Henriksen, R. H., Guldmann, T., Pedersen, N., Saboori, S., Hvid, L., Dahlerup, J. F., Hvas, C. L., Jawhara, M., Andersen, K. W., Pedersen, A. K., Nielsen, O. H., Bergenheim, F., Brodersen, J. B., Heitmann, B. L., Halldorsson, T. I. & 6 others, , 2022, In: Frontiers in Nutrition. 9, 13 p., 985732.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipidomic Trajectories Characterize Delayed Mucosal Wound Healing in Quiescent Ulcerative Colitis and Identify Potential Novel Therapeutic Targets
Bjerrum, Jakob Tveiten , Wang, Y., Zhang, J., Riis, Lene Buhl, Nielsen, Ole Haagen & Seidelin, Jakob Benedict, 2022, In: International Journal of Biological Sciences. 18, 5, p. 1813-1828 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Manipulations and Intestinal Stem Cell-Derived Organoids in Inflammatory Bowel Disease
Boye, T. L., Steenholdt, Casper, Jensen, Kim Bak & Nielsen, Ole Haagen, 2022, In: Stem Cells. 40, 5, p. 447-457Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multiparametric and accurate functional analysis of genetic sequence variants using CRISPR-Select
Niu, Yiyuan, Ferreira Azevedo, Catarina A, Li, Xin, Kamali, E., Nielsen, Ole Haagen, Sørensen, Claus Storgaard & Frödin, Morten, 2022, In: Nature Genetics. 54, 28 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reply
Nielsen, Ole Haagen, Gubatan, J. & Juhl, C. B., 2022, In: Clinical Gastroenterology and Hepatology. 20, 4, p. 963-964Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Selective tyrosine kinase 2 inhibitors in inflammatory bowel disease
Nielsen, Ole Haagen, Boye, T. L., Chakravarti, D. & Gubatan, J., 2022, In: Trends in Pharmacological Sciences. 43, 5, p. 424-436Research output: Contribution to journal › Review › Research › peer-review
- Published
Tuft Cells and Their Role in Intestinal Diseases
Hendel, S. K., Kellermann, L., Hausmann, Annika, Bindslev, Niels, Jensen, Kim Bak & Nielsen, Ole Haagen, 2022, In: Frontiers in Immunology. 13, 13 p., 822867.Research output: Contribution to journal › Review › Research › peer-review
- 2021
- Published
Identification, isolation and analysis of human gut-associated lymphoid tissues
Jørgensen, P. B., Fenton, T. M., Mörbe, U. M., Riis, Lene Buhl, Jakobsen, H. L., Nielsen, Ole Haagen & Agace, W. W., 22 Feb 2021, In: Nature Protocols. 16, p. 2051–2067Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biologics During Pregnancy in Women With Inflammatory Bowel Disease and Risk of Infantile Infections: A Systematic Review and Meta-Analysis
Gubatan, J. M., Nielsen, Ole Haagen, Levitte, S., Juhl, C. B., Maxwell, C., Streett, S. E. & Habtezion, A., 2021, In: Am J Gastroenterol. 116, 2, p. 243-253Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IBD metabonomics predicts phenotype, disease course, and treatment response
Bjerrum, Jakob Tveiten , Wang, Y. L., Seidelin, Jakob Benedict & Nielsen, Ole Haagen, 2021, In: EBioMedicine. 71, 103551.Research output: Contribution to journal › Review › Research › peer-review
- Published
Telomere dysfunction instigates inflammation in inflammatory bowel disease
Chakravarti, D., Lee, R., Multani, A. S., Santoni, A., Keith, Z., Hsu, W. H., Chang, K., Reyes, L., Rashid, A., Wu, C. J., Li, J., Zhang, J., Shim, H. S., Chandra, K., Deng, P., Spring, D. J., Nielsen, O. H., Riis, L. B., Mayigegowda, K. K., Blutt, S. E. & 9 others, , 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 29, e2024853118.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Efficacy and safety of methotrexate in the management of inflammatory bowel disease: A systematic review and meta-analysis of randomized, controlled trials
Nielsen, Ole Haagen, Steenholdt, C., Juhl, C. B. & Rogler, G., Mar 2020, In: EClinicalMedicine. 20, 10 p., 100271.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A fully defined 3D matrix for ex vivo expansion of human colonic organoids from biopsy tissue
Bergenheim, F., Fregni, G., Buchanan, C. F., Riis, Lene Buhl, Heulot, M., Touati, J., Seidelin, Jakob Benedict, Rizzi, S. C. & Nielsen, Ole Haagen, 2020, In: Biomaterials. 262, 11 p., 120248.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immune Profiling of Human Gut-Associated Lymphoid Tissue Identifies a Role for Isolated Lymphoid Follicles in Priming of Region-Specific Immunity
Fenton, T. M., Jørgensen, P. B., Niss, K., Rubin, S. J. S., Mörbe, U. M., Riis, Lene Buhl, Da Silva, C., Plumb, A., Vandamme, J., Jakobsen, H. L., Brunak, Søren, Habtezion, A., Nielsen, Ole Haagen, Johansson-Lindbom, B. & Agace, W. W., 2020, In: Immunity. 52, 3, p. 557-570, e1-e6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mucosal vitamin D signaling in inflammatory bowel disease
Kellermann, L., Jensen, Kim Bak, Bergenheim, F., Gubatan, J., Chou, N. D., Moss, A. & Nielsen, Ole Haagen, 2020, In: Autoimmunity Reviews. 19, 11, 102672.Research output: Contribution to journal › Review › Research › peer-review
- Published
SMAC mimetics and RIPK inhibitors as therapeutics for chronic inflammatory diseases
Jensen, S., Seidelin, Jakob Benedict, LaCasse, E. C. & Nielsen, Ole Haagen, 2020, In: Science Signaling. 13, 619, 18 p., eaax8295.Research output: Contribution to journal › Review › Research › peer-review
- Published
Telomere dysfunction activates YAP1 to drive tissue inflammation
Chakravarti, D., Hu, B., Mao, X., Rashid, A., Li, J., Li, J., Liao, W. T., Whitley, E. M., Dey, P., Hou, P., LaBella, K. A., Chang, A., Wang, G., Spring, D. J., Deng, P., Zhao, D., Liang, X., Lan, Z., Lin, Y., Sarkar, S. & 16 others, , 2020, In: Nature Communications. 11, 13 p., 4766.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Metabonomics in gastroenterology and hepatology
Bjerrum, Jakob Tveiten & Nielsen, Ole Haagen, 1 Aug 2019, In: International Journal of Molecular Sciences. 20, 15, 3638.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Biosimilars for management of Crohn disease
Nielsen, Ole Haagen & Ainsworth, M. A., 2019, In: Annals of Internal Medicine. 170, 2, p. 129-130 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Fluorescence-based tracing of transplanted intestinal epithelial cells using confocal laser endomicroscopy
Bergenheim, F., Seidelin, Jakob Benedict, Pedersen, M. T., Mead, B. E., Jensen, Kim Bak, Karp, J. M. & Nielsen, Ole Haagen, 2019, In: Stem Cell Research & Therapy. 10, 1, p. 1-12 12 p., 148.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Managing vitamin D deficiency in inflammatory bowel disease
Nielsen, Ole Haagen, Hansen, T. I., Gubatan, J. M., Jensen, Kim Bak & Rejnmark, L., 2019, In: Frontline Gastroenterology. 10, 4, p. 394-400 7 p., 31656565.Research output: Contribution to journal › Review › Research › peer-review
- Published
Methotrexate for inflammatory bowel disease: time for reconsideration
Nielsen, Ole Haagen, Ainsworth, M. A. & Steenholdt, Casper, 2019, In: Expert Review of Gastroenterology and Hepatology. 13, 5, p. 407-409 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Systematic review with meta-analysis: association of vitamin D status with clinical outcomes in adult patients with inflammatory bowel disease
Gubatan, J., Chou, N. D., Nielsen, Ole Haagen & Moss, A. C., 2019, In: Alimentary Pharmacology and Therapeutics. 50, 11-12, p. 1146-1158 13 p.Research output: Contribution to journal › Review › Research › peer-review
- 2018
- Published
Intestinal barrier integrity and inflammatory bowel disease: Stem cell-based approaches to regenerate the barrier
Holmberg, F. E. O., Pedersen, J., Jørgensen, P., Soendergaard, C., Jensen, Kim Bak & Nielsen, Ole Haagen, Apr 2018, In: Journal of Tissue Engineering and Regenerative Medicine. 12, 4Research output: Contribution to journal › Review › Research › peer-review
- Published
YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration
Yui, S., Azzolin, L., Maimets, Martti, Pedersen, M. T., Fordham, R. P., Hansen, Stine Lind, Larsen, Hjalte List, Guiu, J., Alves, M. R. P., Friis, Carsten, Johansen, Jens Vilstrup, Li, Yuan, Madsen, C. D., Nakamura, T., Watanabe, M., Nielsen, Ole Haagen, Schweiger, P. J., Piccolo, S. & Jensen, Kim Bak, 1 Jan 2018, In: Cell Stem Cell. 22, 1, p. 35-49. e7 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
COX-2-PGE2 Signaling Impairs Intestinal Epithelial Regeneration and Associates with TNF Inhibitor Responsiveness in Ulcerative Colitis
Li, Yuan, Soendergaard, C., Bergenheim, F. H., Aronoff, D. M., Milne, G., Riis, Lene Buhl, Seidelin, Jakob Benedict, Jensen, Kim Bak & Nielsen, Ole Haagen, 2018, In: EBioMedicine. 36, p. 497-507Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
Boyd, M., Thodberg, M., Vitezic, M., Lange, J. B., Vitting-Seerup, K., Chen, Y., Coskun, M., Li, Y., Lo, B. Z. S., Klausen, P., Schweiger, P., Pedersen, A. G., Rapin, N. P. J-P., Skovgaard, K., Dahlgaard, K., Andersson, R., Terkelsen, T. B., Lilje, B., Troelsen, J. T., Petersen, A. M. & 7 others, , 2018, In: Nature Communications. 9, 19 p., 1661.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of red and processed meat and fibre intake on treatment outcomes among patients with chronic inflammatory diseases: protocol for a prospective cohort study of prognostic factors and personalised medicine
Christensen, R., Heitmann, B. L., Andersen, K. W., Nielsen, O. H., Sørensen, S. B., Jawhara, M., Bygum, A., Hvid, L., Grauslund, J., Wied, J., Glerup, H., Fredberg, U., Villadsen, J. A., Kjær, S. G., Fallingborg, J., Moghadd, S. A. G. R., Knudsen, T., Brodersen, J., Frøjk, J., Dahlerup, J. F. & 21 others, , 2018, In: BMJ Open. 8, 2, 15 p., :e018166.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inflammatory bowel disease with primary sclerosing cholangitis: A Danish population-based cohort study 1977-2011
Sørensen, J. Ø., Nielsen, Ole Haagen, Andersson, M., Ainsworth, M. A., Ytting, H., Bélard, E. & Jess, T., 2018, In: Liver International. 38, 3, p. 532-541Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Putative biomarkers of vedolizumab resistance and underlying inflammatory pathways involved in IBD
Soendergaard, C., Seidelin, Jakob Benedict, Steenholdt, C. & Nielsen, Ole Haagen, 2018, In: B M J Open Gastroenterology. 5, 1, e000208.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rational Management of Iron-Deficiency Anaemia in Inflammatory Bowel Disease
Nielsen, Ole Haagen, Soendergaard, C., Vikner, M. E. & Weiss, G., 2018, In: Nutrients. 10, 1, 25 p., 82.Research output: Contribution to journal › Review › Research › peer-review
- Published
Role of Vitamin D in the Natural History of Inflammatory Bowel Disease
Nielsen, Ole Haagen, Rejnmark, L. & Moss, A. C., 2018, In: Journal of Crohn's and Colitis. 12, 6, p. 742-752 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Targeting JAK-STAT signal transduction in IBD
Soendergaard, C., Bergenheim, F. H., Bjerrum, Jakob Tveiten & Nielsen, Ole Haagen, 2018, In: Pharmacology & Therapeutics. 192, p. 100-111Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Inflammatory Bowel Disease and Small Bowel Cancer Risk, Clinical Characteristics, and Histopathology: A Population-Based Study
Bojesen, R. D., Riis, Lene Buhl, Høgdall, Estrid Vilma Solyom, Nielsen, Ole Haagen & Jess, T., Dec 2017, In: Clinical Gastroenterology and Hepatology. 15, 12, p. 1900-1907.e2Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of Growth Hormone Resistance in Experimental and Ulcerative Colitis
Soendergaard, C., Kvist, P. H., Thygesen, P., Reslow, M., Nielsen, Ole Haagen, Kopchick, J. J. & Holm, T. L., 23 Sep 2017, In: International Journal of Molecular Sciences (Online). 18, 10, 20 p., 2046.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A proposal for a study on treatment selection and lifestyle recommendations in chronic inflammatory diseases: A danish multidisciplinary collaboration on prognostic factors and personalised medicine
Andersen, V., Holmskov, U., Bek Sørensen, S., Jawhara, M., Andersen, K. W., Bygum, A., Hvid, L., Grauslund, J., Wied, J., Glerup, H., Fredberg, U., Villadsen, J. A., Kjær, S. G., Fallingborg, J., Moghadd, S. A. G. R., Knudsen, T., Brodersen, J., Frøjk, J., Dahlerup, J. F., Nielsen, O. H. & 18 others, , May 2017, In: Nutrients. 9, 5, 16 p., 499.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An open prospective study evaluating efficacy and safety of a new medical device for rectal application of activated carbon in the treatment of chronic, uncomplicated perianal fistulas
Zawadzki, A., Johnson, L. B., Bohe, M., Johansson, C., Ekelund, M. & Nielsen, Ole Haagen, Apr 2017, In: International Journal of Colorectal Disease. 32, 4, p. 509-512 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sphingosine-1-phosphate signaling in inflammatory bowel disease
Nielsen, Ole Haagen, Li, Yuan, Lindbom, B. J. & Coskun, M., Apr 2017, In: Trends in Molecular Medicine. 23, 4, p. 362-374 13 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Novel targeted therapies for inflammatory bowel disease
Coskun, M., Vermeire, S. & Nielsen, Ole Haagen, Feb 2017, In: Trends in Pharmacological Sciences. 38, 2, p. 127-142 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Culturing human intestinal stem cells for regenerative applications in the treatment of inflammatory bowel disease
Holmberg, F. E., Seidelin, Jakob Benedict, Yin, X., Mead, B. E., Tong, Z., Li, Yuan, Karp, J. M. & Nielsen, Ole Haagen, 2017, In: EMBO Molecular Medicine. 9, 5, p. 558-570 13 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
How genetic testing can lead to targeted management of XIAP deficiency-related inflammatory bowel disease
Nielsen, Ole Haagen & LaCasse, E. C., 2017, In: Genetics In Medicine. 19, p. 133-143Research output: Contribution to journal › Review › Research › peer-review
- Published
Impact of feedback and monitoring on colonoscopy withdrawal times and polyp detection rates
Nielsen, A. B., Nielsen, Ole Haagen & Hendel, J., 2017, In: BMJ Open Gastroenterology. 4, 6 p., e000142.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabonomics uncovers a reversible proatherogenic lipid profile during infliximab therapy of inflammatory bowel disease
Bjerrum, J. T., Steenholdt, C., Ainsworth, M., Nielsen, Ole Haagen, Reed, M. A. C., Atkins, K., Günther, U. L., Hao, F. & Wang, Y., 2017, In: BMC Medicine. 15, 1, 13 p., 184.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modulation of Gut Microbiota in Pathological States
Wang, Y., Wang, B., Wu, J., Jiang, X., Tang, H. & Nielsen, Ole Haagen, 2017, In: Engineering. 3, 1, p. 83-89 7 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Regulation of laminin γ2 expression by CDX2 in colonic epithelial cells is impaired during active inflammation
Coskun, M., Soendergaard, C., Joergensen, S., Dahlgaard, K., Riis, Lene Buhl, Nielsen, Ole Haagen, Sandelin, Albin Gustav & Troelsen, J. T., 2017, In: Journal of Cellular Biochemistry. 118, 2, p. 298-307 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Relation between NOD2 genotype and changes in innate signaling in Crohn's disease on mRNA and miRNA levels
Chen, Y., Salem, M., Boyd, M., Lange, Jette Bornholdt, Li, Yuan, Coskun, M., Seidelin, Jakob Benedict, Sandelin, Albin Gustav & Nielsen, Ole Haagen, 2017, In: npj Genomic Medicine. 2, 11 p., 3.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Incidence of, phenotypes of and survival from small bowel cancer in Denmark, 1994-2010: a population-based study
Bojesen, R. D., Andersson, M., Riis, Lene Buhl, Nielsen, Ole Haagen & Jess, T., Sep 2016, In: Journal of Gastroenterology. 51, 9, p. 891-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systemic and intestinal levels of factor XIII-A: the impact of inflammation on expression in macrophage subtypes
Søndergaard, C., Kvist, P. H., Seidelin, Jakob Benedict, Pelzer, H. & Nielsen, Ole Haagen, Aug 2016, In: Journal of Gastroenterology. 51, 8, p. 796-807 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms behind efficacy of tumor necrosis factor inhibitors in inflammatory bowel diseases
Olesen, C. M., Coskun, M., Peyrin-Biroulet, L. & Nielsen, Ole Haagen, Mar 2016, In: Pharmacology & Therapeutics. 159, p. 110-119 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating cytokines and cytokine receptors in infliximab treatment failure due to TNF-α independent Crohn disease
Steenholdt, Casper, Coskun, M., Buhl, S., Bendtzen, K., Ainsworth, M. A., Brynskov, J. & Nielsen, Ole Haagen, 2016, In: Medicine (Baltimore). 95, 16, 8 p., e3417.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Iron replacement therapy: do we need new guidelines?
Nielsen, Ole Haagen, Coskun, M. & Weiss, G., 2016, In: Current Opinion in Gastroenterology. 32, 2, p. 128-135 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Pharmacology and optimization of thiopurines and methotrexate in inflammatory bowel disease
Coskun, M., Steenholdt, Casper, de Boer, N. K. & Nielsen, Ole Haagen, 2016, In: Clinical Pharmacokinetics. 55, 3, p. 257-274 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Will novel oral formulations change the management of inflammatory bowel disease?
Nielsen, Ole Haagen, Seidelin, Jakob Benedict, Ainsworth, M. A. & Coskun, M., 2016, In: Expert Opinion on Investigational Drugs. 25, 6, p. 709-718 10 p.Research output: Contribution to journal › Review › Research › peer-review
- 2015
- Published
Impact of T300A Variant of ATG16L1 on Antibacterial Response, Risk of Culture Positive Infections, and Clinical Course of Crohn's Disease
Salem, M., Nielsen, Ole Haagen, Nys, K., Yazdanyar, S. & Seidelin, Jakob Benedict, Nov 2015, In: Clinical and Translational Gastroenterology. 6, 9 p., e122.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preface
Rogler, G., Herfarth, H., Hibi, T. & Nielsen, Ole Haagen, 9 Jul 2015, Anti-Tumor Necrosis Factor Therapy in Inflammatory Bowel Disease. Karger, p. viiiResearch output: Chapter in Book/Report/Conference proceeding › Preface/postscript › Research › peer-review
- Published
Deviations in human gut microbiota: a novel diagnostic test for determining dysbiosis in patients with IBS or IBD
Casén, C., Vebø, H. C., Sekelja, M., Hegge, F. T., Karlsson, M. K., Ciemniejewska, E., Dzankovic, S., Frøyland, C., Nestestog, R., Engstrand, L., Munkholm, Pia, Nielsen, Ole Haagen, Rogler, G., Simrén, M., Öhman, L., Vatn, M. H. & Rudi, K., Jul 2015, In: Alimentary Pharmacology and Therapeutics. 42, 1, p. 71-83 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Management of Iron-Deficiency Anemia in Inflammatory Bowel Disease: A Systematic Review
Nielsen, Ole Haagen, Ainsworth, M., Coskun, M. & Weiss, G., Jun 2015, In: Medicine (Baltimore). 94, 23, p. 1-14 14 p., e963.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Alpha-1 antitrypsin and granulocyte colony-stimulating factor as serum biomarkers of disease severity in ulcerative colitis
Soendergaard, C., Nielsen, Ole Haagen, Seidelin, Jakob Benedict, Kvist, P. H. & Bjerrum, J. T., May 2015, In: Inflammatory Bowel Diseases. 21, 5, p. 1077-88 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ATG16L1: A multifunctional susceptibility factor in Crohn disease
Salem, M., Ammitzboell, M., Nys, K., Seidelin, Jakob Benedict & Nielsen, Ole Haagen, 3 Apr 2015, In: Autophagy. 11, 4, p. 585-94 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Species-specific engagement of human nucleotide oligomerization domain 2 (NOD)2 and Toll-like receptor (TLR) signalling upon intracellular bacterial infection: role of Crohn's associated NOD2 gene variants
Salem, M., Seidelin, Jakob Benedict, Eickhardt-Dalbøge, S. R., Alhede, M., Rogler, G. & Nielsen, Ole Haagen, Mar 2015, In: Clinical and Experimental Immunology. 179, 3, p. 426-34 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IL-33 promotes GATA-3 polarization of gut-derived T cells in experimental and ulcerative colitis
Seidelin, Jakob Benedict, Coskun, M., Kvist, P. H., Holm, T. L., Holgersen, Kristine & Nielsen, Ole Haagen, Feb 2015, In: Journal of Gastroenterology. 50, 2, p. 180-190 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrative Transcriptomic and Metabonomic Molecular Profiling of Colonic Mucosal Biopsies Indicates a Unique Molecular Phenotype for Ulcerative Colitis
Rantalainen, M., Bjerrum, Jakob Tveiten , Olsen, Jørgen, Nielsen, Ole Haagen & Wang, Y., 2 Jan 2015, In: Journal of Proteome Research. 14, 1, p. 479-90 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cellular inhibitor of apoptosis protein 2 controls human colonic epithelial restitution, migration, and Rac1 activation
Seidelin, Jakob Benedict, Larsen, S., Linnemann, D., Vainer, B., Coskun, M., Troelsen, J. T. & Nielsen, Ole Haagen, Jan 2015, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 308, 2, p. G92-G99 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-TNF-α Therapy for Extraintestinal Manifestations of Inflammatory Bowel Disease
Nielsen, Ole Haagen, Bendtzen, K. & Pedersen, J., 2015, In: Frontiers of Gastrointestinal Research. 34, p. 206-213Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabonomics of human fecal extracts characterize ulcerative colitis, Crohn's disease and healthy individuals
Bjerrum, Jakob Tveiten , Wang, Y., Hao, F., Coskun, M., Ludwig, C., Guenther, U. & Nielsen, Ole Haagen, 2015, In: Metabolomics. 11, 1, p. 122-133 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Objective Quantification of Immune Cell Infiltrates and Epidermal Proliferation in Psoriatic Skin: A Comparison of Digital Image Analysis and Manual Counting
Soendergaard, C., Nielsen, Ole Haagen, Skak, K., Røpke, M. A., Seidelin, Jakob Benedict & Kvist, P. H., 2015, In: Applied Immunohistochemistry & Molecular Morphology. p. 1-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role and advances of immunomodulator therapy for inflammatory bowel disease
Nielsen, Ole Haagen, Coskun, M., Steenholdt, Casper & Rogler, G., 2015, In: Expert Review of Gastroenterology & Hepatology. 9, 2, p. 177-189 13 p.Research output: Contribution to journal › Review › Research › peer-review
- 2014
- Published
Transcriptional analysis of left-sided colitis, pancolitis, and ulcerative colitis-associated dysplasia
Bjerrum, Jakob Tveiten , Nielsen, Ole Haagen, Riis, Lene Buhl, Pittet, V., Mueller, C., Rogler, G. & Olsen, Jørgen, Dec 2014, In: Inflammatory Bowel Diseases. 20, 12, p. 2340-2352 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibitors of apoptosis (IAPs) regulate intestinal immunity and inflammatory bowel disease (IBD) inflammation
Pedersen, J., LaCasse, E. C., Seidelin, Jakob Benedict, Coskun, M. & Nielsen, Ole Haagen, Nov 2014, In: Trends in Molecular Medicine. 20, 11, p. 652-65 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prognosis After First-Time Myocardial Infarction in Patients With Inflammatory Bowel Disease According to Disease Activity: Nationwide Cohort Study
Kristensen, S. L., Ahlehoff, O., Lindhardsen, J., Erichsen, R., Lamberts, M., Khalid, U., Nielsen, Ole Haagen, Torp-Pedersen, Christian, Gislason, Gunnar Hilmar & Hansen, Peter Riis, Nov 2014, In: Circulation. Cardiovascular Quality and Outcomes (Print). 7, 6, p. 857-862 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inflammatory Bowel Disease Is Associated With an Increased Risk of Hospitalization for Heart Failure: a Danish Nationwide Cohort A Danish Nationwide Cohort Study
Kristensen, S. L., Ahlehoff, O., Lindhardsen, J., Erichsen, R., Lamberts, M., Khalid, U., Nielsen, Ole Haagen, Torp-Pedersen, C., Gislason, G. H. & Hansen, Peter Riis, Sep 2014, In: Circulation: Heart Failure. 7, 5, p. 717-722 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proximal collagenous gastroenteritides: Clinical management. A systematic review
Nielsen, Ole Haagen, Riis, Lene Buhl, Danese, S., Bojesen, R. D. & Soendergaard, C., Aug 2014, In: Annals of Medicine. 46, 5, p. 311-317 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessment of the validity of a multigene analysis in the diagnostics of inflammatory bowel disease
Bjerrum, Jakob Tveiten , Nyberg, C., Olsen, Jørgen & Nielsen, Ole Haagen, May 2014, In: Journal of Internal Medicine. 275, 5, p. 484-93 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased risk of atrial fibrillation and stroke during active stages of inflammatory bowel disease: a nationwide study
Kristensen, S. L., Lindhardsen, J., Ahlehoff, O., Erichsen, R., Lamberts, M., Khalid, U., Torp-Pedersen, C., Nielsen, Ole Haagen, Gislason, Gunnar Hilmar & Hansen, Peter Riis, Apr 2014, In: Europace. 16, 4, p. 477-484 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inflammatory pathways of importance for management of inflammatory bowel disease
Pedersen, J., Coskun, M., Soendergaard, C., Salem, M. & Nielsen, Ole Haagen, 7 Jan 2014, In: World Journal of Gastroenterology. 20, 1, p. 64-77 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Collagenous sprue: a coeliac disease look-alike with different treatment strategy
Soendergaard, C., Riis, Lene Buhl & Nielsen, Ole Haagen, 2014, In: BMJ Case Reports. 2014Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IBD medications during pregnancy and lactation
Nielsen, Ole Haagen, Maxwell, C. & Hendel, J., 2014, In: Nature Reviews. Gastroenterology & Hepatology. 11, 2, p. 116-127 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Identification of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2
Boyd, M., Coskun, M., Lilje, B., Andersson, Robin, Hoof, I., Lange, Jette Bornholdt, Dahlgaard, K., Olsen, Jørgen, Vitezic, M., Bjerrum, Jakob Tveiten , Seidelin, Jakob Benedict, Nielsen, Ole Haagen, Troelsen, J. & Sandelin, Albin Gustav, 2014, In: D N A Research. 21, 6, p. 569-583 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integration of transcriptomics and metabonomics: improving diagnostics, biomarker identification and phenotyping in ulcerative colitis
Bjerrum, Jakob Tveiten , Rantalainen, M., Wang, Y., Olsen, Jørgen & Nielsen, Ole Haagen, 2014, In: Metabolomics. 10, 2, p. 280-290 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Involvement of CDX2 in the cross talk between TNF-α and Wnt signaling pathway in the colon cancer cell line Caco-2
Coskun, M., Olsen, A. K., Bzorek, M., Holck, S., Engel, U. H., Nielsen, Ole Haagen & Troelsen, J. T., 2014, In: Carcinogenesis. 35, 5, p. 1185-1192 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Letter: European Medicines Agency recommendations for allergic reactions to intravenous iron-containing medicines
Gomollõn, F., Chowers, Y., Danese, S., Dignass, A., Nielsen, Ole Haagen, Lakatos, P. L., Lees, C. W., Lindgren, S., Lukas, M., Mantzaris, G. J., Michetti, P., Moum, B., Peyrin-Biroulet, L., Toruner, M., Van Der Woude, J., Weiss, G., Stoevelaar, H. & Reinisch, W., 2014, In: Alimentary Pharmacology and Therapeutics. 39, 7, p. 743-744Research output: Contribution to journal › Comment/debate › Research
- Published
New strategies for treatment of inflammatory bowel disease
Nielsen, Ole Haagen, 2014, In: Frontiers in Medicine. 1, p. 1-5 5 p., 3.Research output: Contribution to journal › Review › Research › peer-review
- Published
Which Biological Agents Are Most Appropriate for Ulcerative Colitis?
Nielsen, Ole Haagen & Ainsworth, M. A., 2014, In: Annals of Internal Medicine. 160, 10, p. 733-734 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
ID: 4947702
Most downloads
-
1906
downloads
Identification of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
434
downloads
Modulation of Gut Microbiota in Pathological States
Research output: Contribution to journal › Review › Research › peer-review
Published -
367
downloads
YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration
Research output: Contribution to journal › Journal article › Research › peer-review
Published