Ole Haagen Nielsen

Ole Haagen Nielsen

Clinical Professor

Member of:

  • Internal Medicine: Gastroenterology and Hepatology

Primary fields of research

Current research focuses on improvement of diagnosis and pharmacological management of diseases in internal medicine - in particular inflammatory bowel disease. In collaboration with national (Center for Stem Cell Medicine (reNEW) at Panum Institute as well as the Protein Kinase Signaling Group at BRIC, University of Copenhagen) and international research teams (Boston, Helsinki, Houston, Ottawa/Toronto, Redwood City/Stanford, Rochester, Singapore, and Zürich) the importance of the intestinal barrier function for maintenance of homeostasis / development of inflammation is investigated, including the influence of intestinal epithelial cells. Further, the multifactorial interplay of gene-environment interaction (genetics and epigenetics as well as environmental factors, including luminal antigens) in the etiopathogenesis of inflammatory bowel disease is a mainstay of interest-based activity.

Fields of interest

Cellular and molecular mechanisms of inflammation pertinent to clinical and pharmacological improvement of patients with disorders related to internal medicine - with particular spotlight on inflammatory bowel disease. Furthermore, evidence-based management of this disease through pregnancy and lactation.

Safeguarding the undergraduate clinical training of medical students in the fields of internal medicine / medical gastroenterology.
Selected Professional Activities
  • Expert Advisor to the Danish Patient Safety Authority (previously the Danish Health and Medicines Authority) in internal medicine
  • Board member (internal medicine) of the Danish Appeal Tribunal for Patient Injuries
  • Board Member of the European Commission Expert Panel (Representative of the Gastroenterology Panel over a three year period) at Joint Research Centre (JRC), Ispra (VA), to provide scientific opinions. Moreover, member of the Expert Panel of the Innovation and Technology Commission (ITC) of the Hong Kong Special Administrative Region Government. Former member of the Research Board, Faculty of Health and Medical Sciences, University of Copenhagen (including its Executive Committee); Council Member (internal medicine) of the Danish Council for Independent Research (Medical Sciences), the Norwegian Research Council (FRIMEDBIO), the Swedish Research Council (Vetenskapsrådet), and ad hoc Assessor at Horizon Europe (formerly Horizon 2020), the German Research Council (DFG), Science Foundation Ireland, the French High Council for Evaluation of Research and Higher Education (Hcéres), French National Research Agency (ANR), European Research Council, and the Wallenberg Foundation
  • Expert Consultant (medical gastroenterology) at the Danish Medico-Legal Council
  • Member of several editorial committees, including eLife (category of "Medicine"), Drugs, Inflammation Research, Scandinavian Journal of Gastroenterology, and the Danish Electronic Doctor’s Handbook (www.sundhed.dk). Former Scientific Editor of Journal of the Danish Medical Association ("Ugeskrift for Laeger") 2001-2007. Moreover, appointed member of the Danish Bibliometric Research Indicator 2011-2017 (Ministry of Higher Education and Science), hereof Chair of the Expert Panel "Internal Medicine" for 3 years
  • Board member of the Danish Committees on Scientific Dishonesty 2004-2016 - and Editor-in-Chief of "Guidelines for Good Scientific Practice with special focus on health science, natural science and technical science" (to be downloaded as a PDF file via the webpage of the Danish Ministry of Higher Education and Science)
  • Chairman of the written internal medicine board exam at University of Copenhagen (1995-2007), and subsequently Chairman of the written portion of the Danish medical licensing examination (internal medicine and surgery) in accordance with the requirements set by the Danish Patient Safety Authority and aimed for doctors educated in 3rd world countries before being certified to practise in Denmark (2010-2020)

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