Ole Haagen Nielsen

Ole Haagen Nielsen

Clinical Professor

Primary fields of research

Current research focuses on improvement of diagnosis and pharmacological management of diseases in internal medicine - in particular inflammatory bowel disease. In collaboration with national (the Biotech Research and Innovation Centre, University of Copenhagen and University of Southern Denmark) and international research groups (Boston, Houston, Redwood City, Singapore, Toronto (& Ottawa), and Zürich) the importance of the intestinal barrier function for maintenance of homeostasis / development of inflammation is investigated, including the impact of intestinal epithelial cells. Further, the multifactorial interplay of gene-environment interaction (genetics and epigenetics as well as environmental factors, including luminal antigens) in the etiopathogenesis of inflammatory bowel disease is a mainstay of interest-based activity.

Fields of interest

Cellular and molecular mechanisms of inflammation with relevance for clinical and pharmacological improvement of the management of patients with disorders related to internal medicine - with particular spotlight on inflammatory bowel disease.

Safeguarding the undergraduate clinical training of medical students in the fields of internal medicine / medical gastroenterology.
Selected Professional Activities
  • Expert Advisor to the Danish Patient Safety Authority (previously Danish Health and Medicines Authority) in internal medicine
  • Board member (internal medicine) of the Danish Appeal Tribunal for Patient Injuries
  • Member of the European Commission Expert Panel affiliated to the Medical Devices Coordination Group (MDGC) at Joint Research Centre (JRC), Ispra, IT, to provide scientific opinion on clinical evaluation assessment reports 
  • Expert Consultant (medical gastroenterology) at the Danish Medico-Legal Council
  • Reviewer/Evaluator for European Research Council, French National Research Agency (ANR), and previously for the Danish Council for Independent Research (Medical Sciences), the Norwegian Research Council (FRIMEDBIO), the Swedish Research Council (Vetenskapsrådet), German Research Council (DFG), Science Foundation Ireland, the French High Council for Evaluation of Research and Higher Education (Hcéres), Wallenberg Foundation and Horizon 2020
  • Member of several editorial committees, including eLife (section of "Medicine"), Inflammation Research, Scandinavian Journal of Gastroenterology, and the Danish Electronic Doctor’s Handbook (www.sundhed.dk). Former Scientific Editor of Journal of the Danish Medical Association ("Ugeskrift for Laeger") 2001-2007. Moreover, appointed member of the Danish Bibliometric Research Indicator 2011-2017 (Ministry of Higher Education and Science), hereof Chair of the Expert Panel "Internal Medicine" for 3 years
  • Board member of the Danish Committees on Scientific Dishonesty 2004-2016 - and Editor-in-Chief of "Guidelines for Good Scientific Practice with special focus on health science, natural science and technical science" (to be downloaded as a PDF via the webpage of the Danish Ministry of Higher Education and Science)
  • Chairman of the written internal medicine board exam at University of Copenhagen 1995-2007, and Chairman of the written portion of the board qualifying certification exam (internal medicine and surgery) held by the Danish Patient Safety Authority aimed for doctors educated in 3rd world countries applying for license to practice in Denmark 2010-2020

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