Jesper Velgaard Olsen

Jesper Velgaard Olsen

Professor, Deputy Head of Centre, Professor

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    ORCID: 0000-0002-4747-4938

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    1. Published

      Impact of SHP2 tyrosine phosphorylation on the development of acquired resistance to allosteric SHP2 inhibitors

      Franciosa, Giulia & Olsen, Jesper Velgaard, 2023, In: OncoTarget. 14, p. 281-283 3 p.

      Research output: Contribution to journal › Editorial › Research › peer-review

    2. Improved peptide identification in proteomics by two consecutive stages of mass spectrometric fragmentation

      Olsen, Jesper Velgaard & Mann, Matthias, 2004, In: Proceedings of the National Academy of Science of the United States of America. 101, 37, p. 13417-22 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      In Vivo Phosphoproteomics Analysis Reveals the Cardiac Targets of β-Adrenergic Receptor Signaling

      Lundby, Alicia, Andersen, M. N., Steffensen, Annette Buur, Horn, H., Kelstrup, C. D., Francavilla, C., Jensen, Lars Juhl, Schmitt, Nicole, Thomsen, Morten Bækgaard & Olsen, Jesper Velgaard, 4 Jun 2013, In: Science Signaling. 6, 278, p. rs11 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. In-gel digestion for mass spectrometric characterization of proteins and proteomes

      Shevchenko, A., Tomas, H., Havlis, J., Olsen, Jesper Velgaard & Mann, Matthias, 2006, In: Nature Protocols (Print Edition). 1, 6, p. 2856-60 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

      Mootha, V. K., Bunkenborg, J., Olsen, Jesper Velgaard, Hjerrild, M., Wisniewski, J. R., Stahl, E., Bolouri, M. S., Ray, H. N., Sihag, S., Kamal, M., Patterson, N., Lander, E. S. & Mann, Matthias, 2003, In: Cell. 115, 5, p. 629-40 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Integrated proximal proteomics reveals IRS2 as a determinant of cell survival in ALK-driven neuroblastoma

      Emdal, Kristina Bennet, Pedersen, A., Bekker-Jensen, D. B., Lundby, Alicia, Claeys, S., De Preter, K., Speleman, F., Francavilla, C. & Olsen, Jesper Velgaard, 20 Nov 2018, In: Science Signaling. 11, 557, p. 1-17 17 p., eaap9752.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Intramolecular hydrogen atom transfer in hydrogen-deficient polypeptide radical cations

      Nielsen, Michael Lund, Budnik, B. A., Haselmann, K. F., Olsen, Jesper Velgaard & Zubarev, R. A., 2000, In: Chemical Physics Letters. 330, 5-6, p. 558-562 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Investigation of protein-tyrosine phosphatase 1B function by quantitative proteomics

      Mertins, P., Eberl, H. C., Renkawitz, J., Olsen, Jesper Velgaard, Tremblay, M. L., Mann, M., Ullrich, A. & Daub, H., 2008, In: Molecular and Cellular Proteomics. 7, 9, p. 1763-77 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      KIT(D816V) Induces SRC-Mediated Tyrosine Phosphorylation of MITF and Altered Transcription Program in Melanoma

      Phung, B., Kazi, J. U., Lundby, Alicia, Bergsteinsdottir, K., Sun, J., Goding, C. R., Jönsson, G., Olsen, Jesper Velgaard, Steingrímsson, E. & Rönnstrand, L., 2017, In: Molecular cancer research : MCR. 15, 9, p. 1265-1274 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle

      Daub, H., Olsen, Jesper Velgaard, Bairlein, M., Gnad, F., Oppermann, F. S., Körner, R., Greff, Z., Kéri, G., Stemmann, O. & Mann, M., 2008, In: Molecular Cell. 31, 3, p. 438-48 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Large-Scale Phosphoproteomics Reveals Shp-2 Phosphatase-Dependent Regulators of Pdgf Receptor Signaling

      Batth, Tanveer Singh, Papetti, M., Pfeiffer, A., Tollenaere, M. A. X., Francavilla, C. & Olsen, Jesper Velgaard, 2018, In: Cell Reports. 22, 10, p. 2784-2796 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Large-scale proteomics analysis of the human kinome

      Oppermann, F. S., Gnad, F., Olsen, Jesper Velgaard, Hornberger, R., Greff, Z., Kéri, G., Mann, M. & Daub, H., 2009, In: Molecular and Cellular Proteomics. 8, 7, p. 1751-64 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Limits for resolving isobaric tandem mass tag reporter ions using phase constrained spectrum deconvolution

      Kelstrup, C. D., Aizikov, K., Batth, Tanveer Singh, Kreutzman, A., Grinfeld, D., Lange, O., Mourad, D., Makarov, A. A. & Olsen, Jesper Velgaard, 2 Nov 2018, In: Journal of Proteome Research. 17, 11, p. 4008-4016 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Loss of N-terminal acetyltransferase A activity induces thermally unstable ribosomal proteins and increases their turnover in Saccharomyces cerevisiae

      Hernández Guzmán, Ulises, Aksnes, H., Ree, R., Krogh, Nicolai, Jakobsson, M. E., Jensen, Lars Juhl, Arnesen, T. & Olsen, Jesper Velgaard, 2023, In: Nature Communications. 14, 4517.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Lysine acetylation targets protein complexes and co-regulates major cellular functions

      Choudhary, Chunaram, Kumar, C., Gnad, F., Nielsen, Michael Lund, Rehman, M., Walther, T. C., Olsen, Jesper Velgaard & Mann, Matthias, 2009, In: Science. 325, 5942, p. 834-40 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. MAPU: Max-Planck Unified database of organellar, cellular, tissue and body fluid proteomes

      Zhang, Y., Zhang, Y., Adachi, J., Olsen, Jesper Velgaard, Shi, R., de Souza, G., Pasini, E., Foster, L. J., Macek, B., Zougman, A., Kumar, C., Wisniewski, J. R., Jun, W. & Mann, Matthias, Jan 2007, In: Nucleic Acids Research. 35, Database issue, p. D771-9

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. MSQuant, an Open Source Platform for Mass Spectrometry-Based Quantitative Proteomics

      Mortensen, P., Gouw, J. W., Olsen, Jesper Velgaard, Ong, S., Rigbolt, K. T. G., Bunkenborg, J., Cox, J., Foster, L. J., Heck, A. J. R., Blagoev, B., Andersen, J. S. & Mann, Matthias, Jan 2010, In: Journal of Proteome Research.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Mapping cardiac remodeling in chronic kidney disease

      Kaesler, N., Cheng, M., Nagai, J., O'Sullivan, J., Peisker, F., Bindels, E. M. J., Babler, A., Moellmann, J., Droste, P., Franciosa, G., Dugourd, A., Saez-Rodriguez, J., Neuss, S., Lehrke, M., Boor, P., Goettsch, C., Olsen, J. V., Speer, T., Lu, T. S., Lim, K. & 4 others, Floege, J., Denby, L., Costa, I. & Kramann, R., 2023, In: Science Advances. 9, 47, 18 p., eadj4846.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Mass spectrometry-based proteomics of cerebrospinal fluid in pediatric central nervous system malignancies: a systematic review with meta-analysis of individual patient data

      Larsen, Christian Mirian, Thastrup, M., Mathiasen, R., Schmiegelow, Kjeld, Olsen, Jesper Velgaard & Østergaard, Ole, 2024, In: Fluids and Barriers of the CNS. 21, 17 p., 14.

      Research output: Contribution to journal › Review › Research › peer-review

    20. Published

      Mass-Spectrometry Based Proteome Comparison of Extracellular Vesicle Isolation Methods: Comparison of ME-kit, Size-Exclusion Chromatography, and High-Speed Centrifugation

      Askeland, A., Borup, A., Østergaard, Ole, Olsen, Jesper Velgaard, Lund, S. M., Christiansen, G., Kristensen, S. R., Heegaard, N. H. H. & Pedersen, S., 2020, In: Biomedicines. 8, 8, 15 p., 246.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Matrix Gla Protein drives stemness and tumor initiation in ovarian cancer

      Nieddu, V., Melocchi, V., Battistini, C., Franciosa, Giulia, Lupia, M., Stellato, C., Bertalot, G., Olsen, Jesper Velgaard, Colombo, N., Bianchi, F. & Cavallaro, U., 2023, In: Cell Death and Disease. 14, 3, 16 p., 220.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Metaproteomics of saliva identifies human protein markers specific for individuals with periodontitis and dental caries compared to orally healthy controls

      Midjord-Belstrøm, Daniel, Jersie-Christensen, R. R., Lyon, D., Damgaard, Christian, Jensen, Lars Juhl, Holmstrup, Palle & Olsen, Jesper Velgaard, 2016, In: PeerJ. 4, 17 p., e2433.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes

      Choudhary, Chunaram, Olsen, Jesper Velgaard, Brandts, C., Cox, J., Reddy, P. N. G., Böhmer, F. D., Gerke, V., Schmidt-Arras, D., Berdel, W. E., Müller-Tidow, C., Mann, Matthias & Serve, H., 2009, In: Molecular Cell. 36, 2, p. 326-39 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Molecular Basis of the Mechanisms Controlling MASTL

      Hermida, D., Mortuza, G. B., Pedersen, A., Pozdnyakova, I., Nguyen, T. T. T. N., Maroto, M., Williamson, M., Ebersole, T., Cazzamali, G., Rand, Kasper Dyrberg, Olsen, Jesper Velgaard, Malumbres, M. & Montoya, Guillermo, 2020, In: Molecular & Cellular Proteomics. 19, 2, p. 326-343

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Molecular basis of Tousled-Like Kinase 2 activation

      Mortuza, G. B., Hermida, D., Pedersen, A., Segura-Bayona, S., López-Méndez, B., Redondo, P., Rüther, P., Pozdnyakova, I., Garrote, A. M., Muñoz, I. G., Villamor-Payà, M., Jauset, C., Olsen, Jesper Velgaard, Stracker, T. H. & Montoya, Guillermo, 2018, In: Nature Communications. 9, 1, p. 2535 2535.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Molecular evidence of use of hide glue in 4th millennium BC Europe

      Bleicher, N., Kelstrup, C., Olsen, Jesper Velgaard & Cappellini, Enrico, 2015, In: Journal of Archaeological Science. 63, p. 65-71 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Multi-omic detection of Mycobacterium leprae in archaeological human dental calculus

      Fotaki, Anna Katerina, Denham, S. D., Mackie, Meaghan, Iraeta Orbegozo, Miren, Mylopotamitaki, Dorothea, Gopalakrishnan, Shyam, Sicheritz-Pontén, Thomas, Olsen, Jesper Velgaard, Cappellini, Enrico, KU, thw266, Christophersen, A., Gilbert, M Thomas P & Vågene, Åshild Joanne, 2020, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 375, 1812, 10 p., 20190584.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Multi-protease analysis of Pleistocene bone proteomes

      Lanigan, Liam Thomas, Mackie, Meaghan, Feine, S., Hublin, J., Schmitz, R. W., Wilcke, A., Collins, Matthew James, Cappellini, Enrico, Olsen, Jesper Velgaard, Taurozzi, Alberto John & Welker, Frido, 30 Sep 2020, In: Journal of Proteomics. 228, 11 p., 103889.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Multi-spectra peptide sequencing and its applications to multistage mass spectrometry

      Bandeira, N., Olsen, Jesper Velgaard, Mann, M. & Pevzner, P. A., 2008, In: Bioinformatics. 24, 13, p. i416-23

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking

      Francavilla, C., Papetti, M., Rigbolt, K. T. G., Pedersen, A., Sigurdsson, J. O., Cazzamali, G., Karemore, G., Blagoev, B. & Olsen, Jesper Velgaard, Jun 2016, In: Nature Structural and Molecular Biology. 23, 6, p. 608–618 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Nanoelectrospray peptide mapping revisited: Composite survey spectra allow high dynamic range protein characterization without LCMS on an orbitrap mass spectrometer

      Lu, A., Waanders, L. F., Almeida, R., Li, G., Allen, M., Cox, J., Olsen, Jesper Velgaard, Bonaldi, T. & Mann, Matthias, 1 Dec 2007, In: International Journal of Mass Spectrometry. 268, 2-3, p. 158-167 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation

      Knipscheer, P., van Dijk, W. J., Olsen, Jesper Velgaard, Mann, Matthias & Sixma, T. K., 2007, In: EMBO Journal. 26, 11, p. 2797-807 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Obtaining Complete Human Proteomes

      Martinez Del Val, Ana, Hernández Guzmán, Ulises & Olsen, Jesper Velgaard, 2022, In: Annual Review of Genomics and Human Genetics. 23, p. 10.1-10.23 23 p.

      Research output: Contribution to journal › Review › Research › peer-review

    34. Published

      Off-Line High-pH Reversed-Phase Fractionation for In-Depth Phosphoproteomics

      Batth, Tanveer Singh, Francavilla, C. & Olsen, Jesper Velgaard, 4 Nov 2014, In: Journal of Proteome Research. 13, 12, p. 6176-86 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Offline High pH Reversed-Phase Peptide Fractionation for Deep Phosphoproteome Coverage

      Batth, Tanveer Singh & Olsen, Jesper Velgaard, 2016, Phospho-Proteomics: Methods and Protocols. Stechow, L. V. (ed.). Springer, Vol. 1355. p. 179-92 14 p. (Methods in molecular biology (Clifton, N.J.)).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    36. Published

      Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites

      Lundby, Alicia, Franciosa, Giulia, Emdal, Kristina Bennet, Refsgaard, J. C., Gnosa, S. P., Bekker-Jensen, D. B., Secher, A., Maurya, S. R., Paul, I., Mendez, B. L., Kelstrup, C. D., Francavilla, C., Kveiborg, Marie, Montoya, Guillermo, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2019, In: Cell. 179, 2, p. 543-560

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      One-Tip enables comprehensive proteome coverage in minimal cells and single zygotes: [Inkl. Correction]

      Ye, Z., Sabatier, Pierre Camille, Martin Gonzalez, Javier, Eguchi, A., Lechner, Maico Yannic, Østergaard, Ole, Xie, J., Guo, Y., Schultz, L., Truffer, R., Bekker-Jensen, D. B., Bache, N. & Olsen, Jesper Velgaard, 2024, In: Nature Communications. 15, 1, 10 p., 2474.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Optimal analytical strategies for sensitive and quantitative phosphoproteomics using TMT-based multiplexing

      Koenig, Claire, Martinez-Val, A., Franciosa, Giulia & Olsen, Jesper Velgaard, 2022, In: Proteomics. 22, 19-20, 13 p., 2100245.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Optimized Fast and Sensitive Acquisition Methods for Shotgun Proteomics on a Quadrupole Orbitrap Mass Spectrometer

      Kelstrup, C. D., Young, C., Lavallee, R., Nielsen, Michael Lund & Olsen, Jesper Velgaard, 2012, In: Journal of Proteome Research. p. 3487-3497 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Optimizing Linear Ion-Trap Data-Independent Acquisition toward Single-Cell Proteomics

      Phlairaharn, T., Ye, Z., Krismer, Elena, Pedersen, A. K., Pietzner, M., Olsen, Jesper Velgaard, Schoof, E. M. & Searle, B. C., 2023, In: Analytical Chemistry. 95, 26, p. 9881-9891 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. PHOSIDA (phosphorylation site database): management, structural and evolutionary investigation, and prediction of phosphosites

      Gnad, F., Ren, S., Cox, J., Olsen, Jesper Velgaard, Macek, B., Oroshi, M. & Mann, Matthias, 2007, In: Genome Biology. 8, 11, p. R250

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      PKD Phosphorylation as Novel Pathway of KV11.1 Regulation

      Steffensen, Annette Buur, Bomholtz, Sofia Hammami, Andersen, M. N., Olsen, Jesper Velgaard, Mutsaers, N., Lundegaard, Pia Rengtved, Lundby, Alicia & Schmitt, Nicole, 2018, In: Cellular Physiology and Biochemistry. 47, 4, p. 1742-1750 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      PRIME-XS, a European infrastructure for proteomics

      Raijmakers, R., Olsen, Jesper Velgaard, Aebersold, R. & Heck, A. J. R., 23 Jun 2014, In: Molecular & Cellular Proteomics. 13, 8, p. 1901-1904 4 p.

      Research output: Contribution to journal › Editorial › Research › peer-review

    44. Published

      PRMT5-mediated regulatory arginine methylation of RIPK3

      Chauhan, C., Martinez Del Val, Ana, Niedenthal, R., Olsen, Jesper Velgaard, Kotlyarov, A., Bekker-Jensen, Simon Holst, Gaestel, M. & Menon, M. B., 2023, In: Cell Death Discovery. 9, 9 p., 14.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Palaeoproteomic Profiling of Conservation Layers on a 14th Century Italian Wall Painting

      Mackie, Meaghan, Rüther, P. L., Samodova, D., Di Gianvincenzo, Fabiana, Granzotto, C., Lyon, D., Peggie, D. A., Howard, H., Harrison, L., Jensen, Lars Juhl, Olsen, Jesper Velgaard & Cappellini, Enrico, 2018, In: Angewandte Chemie (International ed. in English). 57, 25, p. 7369-7374 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Palaeoproteomic analysis of Early Pleistocene Gigantopithecus blacki

      Welker, Frido, Ramos Madrigal, Jazmin, Wang, W., Kuhlwilm, M., Montero, M. D. M., Demeter, Fabrice, Lalueza-Fox, C., Marques-Bonet, T., Olsen, Jesper Velgaard & Cappellini, Enrico, Mar 2019, In: American Journal of Physical Anthropology. 168, suppl. 68, p. 265-266

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    47. Published

      Palaeoproteomic identification of breast milk protein residues from the archaeological skeletal remains of a neonatal dog

      Tsutaya, T., Mackie, Meaghan, Koenig, C., Sato, T., Weber, A. W., Kato, H., Olsen, Jesper Velgaard & Cappellini, Enrico, 2019, In: Scientific Reports. 9, 7 p., 12841.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Palaeoproteomics resolves sloth relationships

      Presslee, S., Slater, G. J., Pujos, F., Forasiepi, A. M., Fischer, R., Molloy, K., Mackie, M., Olsen, J. V., Kramarz, A., Taglioretti, M., Scaglia, F., Lezcano, M., Lanata, J. L., Southon, J., Feranec, R., Bloch, J., Hajduk, A., Martin, F. M., Salas Gismondi, R., Reguero, M. & 6 others, de Muizon, C., Greenwood, A., Chait, B. T., Penkman, K., Collins, Matthew James & MacPhee, R. D. E., 2019, In: Nature Ecology & Evolution. 3, p. 1121-1130

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Parts per million mass accuracy on an Orbitrap mass spectrometer via lock mass injection into a C-trap

      Olsen, Jesper Velgaard, de Godoy, L. M. F., Li, G., Macek, B., Mortensen, P., Pesch, R., Makarov, A., Lange, O., Horning, S. & Mann, Matthias, 2005, In: Molecular and Cellular Proteomics. 4, 12, p. 2010-21 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Pathogens and host immunity in the ancient human oral cavity

      Warinner, C., Rodrigues, J. F. M., Vyas, R., Trachsel, C., Shved, N., Grossmann, J., Radini, A., Hancock, Y., Tito, R. Y., Fiddyment, S., Speller, C., Hendy, J., Charlton, S., Luder, H. U., Salazar-García, D. C., Eppler, E., Seiler, R., Hansen, L. H., Samaniego Castruita, J. A., Barkow-Oesterreicher, S. & 12 others, Teoh, K. Y., Kelstrup, C., Olsen, Jesper Velgaard, Nanni, P., Kawai, T., Willerslev, Eske, von Mering, C., Lewis, C. M., Collins, M. J., Gilbert, M Thomas P, Rühli, F. & Cappellini, Enrico, 2014, In: Nature Genetics. 46, p. 336-344 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 9925376