Ole Haagen Nielsen

Ole Haagen Nielsen

Clinical Professor

Member of:

  • Internal Medicine: Gastroenterology and Hepatology

ORCID: 0000-0003-4612-8635

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  1. Published

    COLAR: open-label clinical study of IL-6 blockade with tocilizumab for the treatment of immune checkpoint inhibitor-induced colitis and arthritis

    Holmstroem, R. B., Nielsen, Ole Haagen, Jacobsen, Søren, Riis, Lene Buhl, Theile, S., Bjerrum, Jakob Tveiten , Vilmann, Peter, Johansen, Julia Sidenius, Boisen, M. K., Eefsen, R. H. L., Svane, Inge Marie, Nielsen, Dorte Lisbet & Chen, I. M., 2022, In: Journal for ImmunoTherapy of Cancer. 10, 9

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    COX-2-PGE2 Signaling Impairs Intestinal Epithelial Regeneration and Associates with TNF Inhibitor Responsiveness in Ulcerative Colitis

    Li, Yuan, Soendergaard, C., Bergenheim, F. H., Aronoff, D. M., Milne, G., Riis, Lene Buhl, Seidelin, Jakob Benedict, Jensen, Kim Bak & Nielsen, Ole Haagen, 2018, In: EBioMedicine. 36, p. 497-507

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Ca2+ response in neutrophils after exposure to bacterial N-formyl-methionyl-leucyl-phenylalanine: delayed response in ulcerative colitis

    Vainer, B., Lamberth, K., Brimnes, J., Nielsen, Ole Haagen & Claesson, Mogens Helweg, 1 Mar 2003, In: European Journal of Gastroenterology and Hepatology. 15, 3, p. 267-73 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Calcium absorption and acceptance of low-lactose milk among children with primary lactase deficiency

    Nielsen, Ole Haagen, Schiøtz, P. O., Rasmussen, S. N. & Krasilnikoff, P. A., 1984, In: Journal of Pediatric Gastroenterology and Nutrition. 3, 2, p. 219-23 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Caspase 14 does not influence intestinal epithelial cell differentiation

    Seidelin, Jakob Benedict, Sträter, J. & Nielsen, Ole Haagen, Mar 2013, In: Cell Death and Differentiation. 20, 3, p. 524

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Cellular inhibitor of apoptosis protein 2 controls human colonic epithelial restitution, migration, and Rac1 activation

    Seidelin, Jakob Benedict, Larsen, S., Linnemann, D., Vainer, B., Coskun, M., Troelsen, J. T. & Nielsen, Ole Haagen, Jan 2015, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 308, 2, p. G92-G99 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Changed colonic profile of P-selectin, platelet-endothelial cell adhesion molecule-1 (PECAM-1) intercellular adhesion rnolecule-1 (ICAM-1), ICAM-2, and ICAM-3 in inflammatory bowel disease

    Vainer, B. & Nielsen, Ole Haagen, 11 Sep 2000, In: Clinical and Experimental Immunology. 121, 2, p. 242-247 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Changes in Extent of Ulcerative Colitis: A Study on the Course and Prognostic Factors

    Langholz, Ebbe, Munkholm, Pia, Davidsen, M., Nielsen, Ole Haagen & Binder, V., 1 Jan 1996, In: Scandinavian Journal of Gastroenterology. 31, 3, p. 260-266 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Characterization of Growth Hormone Resistance in Experimental and Ulcerative Colitis

    Soendergaard, C., Kvist, P. H., Thygesen, P., Reslow, M., Nielsen, Ole Haagen, Kopchick, J. J. & Holm, T. L., 23 Sep 2017, In: International Journal of Molecular Sciences (Online). 18, 10, 20 p., 2046.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies

    Boyd, M., Thodberg, M., Vitezic, M., Lange, J. B., Vitting-Seerup, K., Chen, Y., Coskun, M., Li, Y., Lo, B. Z. S., Klausen, P., Schweiger, P., Pedersen, A. G., Rapin, N. P. J-P., Skovgaard, K., Dahlgaard, K., Andersson, R., Terkelsen, T. B., Lilje, B., Troelsen, J. T., Petersen, A. M. & 7 others, Jensen, Kim Bak, Gögenur, Ismail, Thielsen, P., Seidelin, Jakob Benedict, Nielsen, Ole Haagen, Bjerrum, Jakob Tveiten & Sandelin, Albin Gustav, 2018, In: Nature Communications. 9, 19 p., 1661.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Chemotactic properties of ICAM-1 and PECAM-1 on neutrophil granulocytes in ulcerative colitis: Effects of prednisolone and mesalazine

    Vainer, B. & Nielsen, Ole Haagen, 24 Aug 2000, In: Alimentary Pharmacology and Therapeutics. 14, 8, p. 1023-1031 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Chronic inflammation: importance of NOD2 and NALP3 in interleukin-1beta generation

    Ferrero-Miliani, L., Nielsen, Ole Haagen, Andersen, P. S. & Girardin, S. E., Feb 2007, In: Clinical and Experimental Immunology. 147, 2, p. 227-35 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  13. Published

    Circulating L-selectin levels and endothelial CD34 expression in inflammatory bowel disease

    Seidelin, Jakob Benedict, Vainer, B., Horn, T. & Nielsen, Ole Haagen, Oct 1998, In: The American Journal of Gastroenterology. 93, 10, p. 1854-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Circulating and mucosal concentrations of tumour necrosis factor and inhibitor(s) in chronic inflammatory bowel disease

    Nielsen, Ole Haagen, Brynskov, J. & Bendtzen, K., Apr 1993, In: Danish Medical Bulletin (Print). 40, 2, p. 247-9 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Circulating cytokines and cytokine receptors in infliximab treatment failure due to TNF-α independent Crohn disease

    Steenholdt, Casper, Coskun, M., Buhl, S., Bendtzen, K., Ainsworth, M. A., Brynskov, J. & Nielsen, Ole Haagen, 2016, In: Medicine (Baltimore). 95, 16, 8 p., e3417.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Circulating soluble intercellular adhesion molecule-1 (sICAM-1) in active inflammatory bowel disease

    Nielsen, Ole Haagen, Langholz, Ebbe, Hendel, J. & Brynskov, J., Sep 1994, In: Digestive Diseases and Sciences. 39, 9, p. 1918-23 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Circulating soluble interleukin-2 receptor alpha and beta chain in inflammatory bowel disease

    Nielsen, Ole Haagen, Ciardelli, T., Wu, Z., Langholz, Ebbe & Kirman, I., Aug 1995, In: The American Journal of Gastroenterology. 90, 8, p. 1301-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Clinical evidence supporting the radical scavenger mechanism of 5-aminosalicylic acid

    Ahnfelt-Rønne, I., Nielsen, Ole Haagen, Christensen, A., Langholz, Ebbe, Binder, V. & Riis, P., May 1990, In: Gastroenterology. 98, 5 Pt 1, p. 1162-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Clinical phenotype and gene expression profile in Crohn's disease

    vlz241, vlz241, Nielsen, Ole Haagen, Borup, R., Nielsen, Finn Cilius & Olsen, Jørgen, 2007, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 292, 1, p. G298-G304

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Colitis ulcerosa

    Nielsen, Ole Haagen, Jess, T., Bjerrum, Jakob Tveiten & Seidelin, Jakob Benedict, 2013, In: Ugeskrift for Laeger. 175, 20, p. 1412-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Collagenous sprue: a coeliac disease look-alike with different treatment strategy

    Soendergaard, C., Riis, Lene Buhl & Nielsen, Ole Haagen, 2014, In: BMJ Case Reports. 2014

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Colonic epithelial cell expression of ICAM-1 relates to loss of surface continuity: a comparative study of inflammatory bowel disease and colonic neoplasms

    Vainer, B., Horn, T. & Nielsen, Ole Haagen, Mar 2006, In: Scandinavian Journal of Gastroenterology. 41, 3, p. 318-25 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Colonic expression and synthesis of interleukin 13 and interleukin 15 in inflammatory bowel disease

    Vainer, B., Nielsen, Ole Haagen, Hendel, J., Horn, T. & Kirman, I., 1 Jan 2000, In: Cytokine. 12, 10, p. 1531-1536 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Comparative onset of effect of biologics and small molecules in moderate-to-severe ulcerative colitis: a systematic review and network meta-analysis

    Attauabi, M., Dahl, E. K., Burisch, J., Gubatan, J., Nielsen, Ole Haagen & Seidelin, Jakob Benedict, 2023, In: EClinicalMedicine. 57, 3, 101866.

    Research output: Contribution to journal › Review › Research › peer-review

  25. Published

    Comparative studies of superoxide production by microbial wall product-primed neutrophils in ulcerative colitis

    Nielsen, S. E., Vainer, B. & Nielsen, Ole Haagen, 1 May 2004, In: Digestive Diseases and Sciences. 49, 5, p. 878-882 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Comparative studies of the colonic in situ expression of intercellular adhesion molecules (ICAM-1, -2, and -3), β2 integrins (LFA-1, Mac-1, and p150,95), and PECAM-1 in ulcerative colitis and Crohn's disease

    Vainer, B., Nielsen, Ole Haagen & Horn, T., 1 Aug 2000, In: American Journal of Surgical Pathology. 24, 8, p. 1115-1124 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Comparison of an Open and a Closed Tube System for Collection of Jejunal Juice

    Rasmussen, S. N., Nielsen, Ole Haagen, Justesen, T., Jacobsen, I. E., Lave, J. & Magid, E., 1 May 1983, In: Scandinavian Journal of Gastroenterology. 18, 3, p. 353-357

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Concentrations of IgA, secretory IgA, IgM, secretory IgM, IgD, and IgG in the upper jejunum of children without gastrointestinal disorders

    Hjelt, K., Sørensen, C. H., Nielsen, Ole Haagen & Krasilnikoff, P. A., 1 Nov 1988, In: Journal of Pediatric Gastroenterology and Nutrition. 7, 6, p. 867-71 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Continuous cytokine exposure of colonic epithelial cells induces DNA damage

    Seidelin, Jakob Benedict & Nielsen, Ole Haagen, Mar 2005, In: European journal of gastroenterology & hepatology. 17, 3, p. 363-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Continuous interferon-gamma or tumor necrosis factor-alpha exposure of enterocytes attenuates cell death responses

    Seidelin, Jakob Benedict, Jäättelä, M. & Nielsen, Ole Haagen, 2004, In: Cytokine. 27, 4-5, p. 113-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Correction: Disease activity in inflammatory bowel disease is associated with increased risk of myocardial infarction, stroke and cardiovascular death - A danish nationwide cohort study (PLoS ONE)

    Kristensen, S. L., Ahlehoff, O., Lindhardsen, Jesper, Erichsen, R., Jensen, G. V., Torp-Pedersen, Christian, Nielsen, Ole Haagen, Gislason, Gunnar Hilmar & Hansen, Peter Riis, 29 Apr 2013, In: PLoS ONE. 8, 4

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  32. Published

    Correlation between circulating soluble ICAM-1 and rednisolone-induced amelioration of ulcerative colitis

    Vainer, B. & Nielsen, Ole Haagen, 1 Mar 2003, In: Scandinavian Journal of Gastroenterology. 38, 3, p. 283-287 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Culturing human intestinal stem cells for regenerative applications in the treatment of inflammatory bowel disease

    Holmberg, F. E., Seidelin, Jakob Benedict, Yin, X., Mead, B. E., Tong, Z., Li, Yuan, Karp, J. M. & Nielsen, Ole Haagen, 2017, In: EMBO Molecular Medicine. 9, 5, p. 558-570 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  34. Published

    Cysteinylleukotrieners betydning for kronisk inflammation og neoplasi i tarmen

    Broom, O. J. & Nielsen, Ole Haagen, 2009, In: Ugeskrift for læger. 171, 4, p. 243-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Cystic fibrosis in Denmark 1945 to 1985. An analysis of incidence, mortality and influence of centralized treatment on survival

    Nielsen, Ole Haagen, Thomsen, Birthe Lykke Riegels, Green, A., Andersen, Per Kragh, Hauge, M. & Schiøtz, P. O., Nov 1988, In: Acta Paediatrica Scandinavica. 77, 6, p. 836-41 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Cystic fibrosis in Denmark in the period 1945‐1981: Evaluation of centralized treatment

    Nielsen, Ole Haagen & Oluf Schiøtz, P., 1982, In: Acta Paediatrica Scandinavica. p. 107-119

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Cytokines (immunoinflammatory hormones) and their natural regulation in inflammatory bowel disease (Crohn's disease and ulcerative colitis): a review

    Brynskov, J., Nielsen, Ole Haagen, Ahnfelt-Rønne, I. & Bendtzen, K., 1 Sep 1994, In: Digestive Diseases. 12, 5, p. 290-304 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  38. Published

    Cytokines and organ failure in acute pancreatitis: inflammatory response in acute pancreatitis

    Malmstrøm, M. L., Hansen, M. B., Andersen, A. M., Ersbøll, A. K., Nielsen, Ole Haagen, Jørgensen, Lars Nannestad & Novovic, S., 2012, In: Pancreas. 41, 2, p. 271-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Cytokines in inflammatory bowel disease

    Brynskov, J., Nielsen, Ole Haagen, Ahnfelt-Rønne, I. & Bendtzen, K., Nov 1992, In: Scandinavian Journal of Gastroenterology. 27, 11, p. 897-906 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  40. Published

    Dagens Medicin: Katastrofalt spild af forskningsressourcer.

    Jørgensen, Povl & Nielsen, Ole Haagen, 10 Jan 2005, In: Ugeskrift for Laeger. 167, 2, 1 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  41. Published

    De frie oxygenradikalers betydning for patogenesen ved kronisk inflammatorisk tarmsygdom

    Nielsen, Ole Haagen & Ahnfelt-Rønne, I., 14 Sep 1992, In: Ugeskrift for Laeger. 154, 38, p. 2544-6 3 p.

    Research output: Contribution to journal › Review › Research › peer-review

  42. Demonstration of circulating immune complexes by the indirect leucocyte phagocytosis test in chronic inflammatory bowel disease. Relation to results of a standard complement consumption assay

    Elmgreen, J., Wiik, A., Nielsen, Henrik & Nielsen, Ole Haagen, 1985, In: Acta Medica Scandinavica. 218, 1, p. 73-78 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Deucravacitinib (Sotyktu™) for plaque psoriasis

    Granau, Agnete Marie, Boye, T. L., Jensen, Kim Bak & Nielsen, Ole Haagen, 2023, In: Trends in Pharmacological Sciences. 44, 4, p. 252-253

    Research output: Contribution to journal › Letter › Research › peer-review

  44. Published

    Deviations in human gut microbiota: a novel diagnostic test for determining dysbiosis in patients with IBS or IBD

    Casén, C., Vebø, H. C., Sekelja, M., Hegge, F. T., Karlsson, M. K., Ciemniejewska, E., Dzankovic, S., Frøyland, C., Nestestog, R., Engstrand, L., Munkholm, Pia, Nielsen, Ole Haagen, Rogler, G., Simrén, M., Öhman, L., Vatn, M. H. & Rudi, K., Jul 2015, In: Alimentary Pharmacology and Therapeutics. 42, 1, p. 71-83 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Diagnosis and Pharmacological Management of Microscopic Colitis in Geriatric Care

    Nielsen, Ole Haagen & Pardi, D. S., 2024, In: Drugs and Aging. 41, p. 113-123 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Diagnosis and management of fistulizing Crohn's disease

    Nielsen, Ole Haagen, Rogler, G., Hahnloser, D., Thomsen, O. Ø. & Medscape, M., 2009, In: Nature Clinical Practice Gastroenterology & Hepatology. 6, 2, p. 92-106 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Diagnosis of ulcerative colitis before onset of inflammation by multivariate modeling of genome-wide gene expression data

    Olsen, Jørgen, Gerds, Thomas Alexander, Seidelin, Jakob Benedict, Csillag, C., Bjerrum, Jakob Tveiten , Troelsen, J. T. & Nielsen, Ole Haagen, 2009, In: Inflammatory Bowel Diseases. 15, 7, p. 1032-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Diarré ved antibiotika forebygges ikke med laktoog bifidobakterier

    Nielsen, Ole Haagen, 31 Dec 2013, In: Ugeskrift for Laeger. 175, 44, 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  49. Published

    Digestive Disease Week 2001. Novel therapeutic principles in inflammatory bowel disease. 20-23 May 2001, Atlanta, GA, USA

    Seidelin, Jakob Benedict & Nielsen, Ole Haagen, Aug 2001, In: I Drugs: the Investigational Drugs Journal. 4, 8, p. 874-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Disease activity in inflammatory bowel disease is associated with increased risk of myocardial infarction, stroke and cardiovascular death - a danish nationwide cohort study

    Kristensen, S. L., Ahlehoff, O., Lindhardsen, J., Erichsen, R., Jensen, G. V. H., Torp-Pedersen, Christian, Nielsen, Ole Haagen, Gislason, Gunnar Hilmar & Hansen, Peter Riis, 2013, In: P L o S One. 8, 2, p. e56944

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 4947702