Jens Juul Holst

Jens Juul Holst

Professor


  1. 2021
  2. Published

    Healthy Weight Loss Maintenance with Exercise, Liraglutide, or Both Combined

    Lundgren, J. R., Janus, C., Jensen, Simon Birk Kjær, Juhl, C. R., Olsen, L. M., Christensen, R. M., Svane, M. S., Bandholm, Thomas Quaade, Bojsen-Møller, K. N., Blond, Martin Bæk, Jensen, Jens-Erik Beck, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 6 May 2021, In: New England Journal of Medicine. 384, p. 1719-1730 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Pancreatic polypeptide: A potential biomarker of glucose-dependent insulinotropic polypeptide receptor activation in vivo

    Veedfald, Simon, Bergmann, N. C., Vilsbøll, Tina, Christensen, Mikkel Bring, Holst, Jens Juul & Knop, Filip Krag, May 2021, In: Diabetic Medicine Online. 38, 8, e14592.

    Research output: Contribution to journalLetterResearchpeer-review

  4. Published

    Effects of endogenous GIP in patients with type 2 diabetes

    Stensen, S., Gasbjerg, Lærke Smidt, Krogh, L. L., Skov-Jeppesen, Kirsa, wbf943, wbf943, Jensen, M. H., Dela, Flemming, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette, Christensen, Mikkel Bring & Knop, Filip Krag, Apr 2021, In: European Journal of Endocrinology. 185, 1, p. 33-45

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Metabolic effects of one-week binge drinking and fast food intake during Roskilde Festival in young healthy male adults

    Demant, Mia Grønlund, Suppli, M. P., Foghsgaard, S., Gether, L., Grøndahl, M. F. G., Dalsgaard, N. B., Bergmann, S. S., Lanng, A. R., Gasbjerg, Lærke Smidt, Thomasen, M., Bagger, J. I., Strandberg, C., Kønig, M. J., Grønbæk, H., Becker, U., Holst, Jens Juul, Knop, J., Gillum, M. P., Vilsbøll, Tina & Knop, Filip Krag, Apr 2021, In: European Journal of Endocrinology. 185, 1, p. 23-32

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Acute hypoglycemia and risk of cardiac arrhythmias in insulin-treated type 2 diabetes and controls

    Andersen, A., Bagger, J. I., Baldassarre, M. P., Christensen, Mikkel Bring, Abelin, K. U., Faber, Jens, Pedersen-Bjerregaard, U., Holst, Jens Juul, Lindhardt, T. B., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2021, In: European Journal of Endocrinology. 185, 2, p. 343-353 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Acute ketosis inhibits appetite and decreases plasma concentrations of acyl ghrelin in healthy humans

    Vestergaard, E. T., Zubanovic, N. B., Rittig, N., Møller, N., Kuhre, Rune Ehrenreich, Holst, Jens Juul, Rehfeld, Jens Frederik & Thomsen, H. H., 2021, In: Diabetes, Obesity and Metabolism. 23, 8, p. 1834-1842

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Age-dependent transition from islet insulin hypersecretion to hyposecretion in mice with the long QT-syndrome loss-of-function mutation Kcnq1-A340V

    Lubberding, Anniek Frederike, Zhang, J., Lundh, M., Nielsen, Thomas Svava, Søndergaard, M. S., Villadsen, M., Skovhøj, E. Z., Boer, G. A., Hansen, J. B., Thomsen, Morten Bækgaard, Treebak, Jonas Thue, Holst, Jens Juul, Kanters, Jørgen K., Mandrup-Poulsen, Thomas, Jespersen, Thomas, Emanuelli, Brice & Torekov, Signe Sørensen, 2021, In: Scientific Reports. 11, 1, 14 p., 12253.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Amino acids differ in their capacity to stimulate GLP-1 release from the perfused rat small intestine and stimulate secretion by different sensing mechanisms

    Modvig, Ida Marie, Kuhre, Rune Ehrenreich, Jepsen, Sara Lind, Xu, S., Engelstoft, M. S., Egerod, Kristoffer Lihme, Schwartz, Thue W., Ørskov, Cathrine, Rosenkilde, Mette & Holst, Jens Juul, 2021, In: American Journal of Physiology: Endocrinology and Metabolism. 320, p. E874-E885 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published
  11. Published

    Associations between ghrelin and leptin and neural food cue reactivity in a fasted and sated state

    Wever, M. C. M., van Meer, F., Charbonnier, L., Crabtree, D. R., Buosi, W., Giannopoulou, A., Androutsos, O., Johnstone, A. M., Manios, Y., Meek, C. L., Holst, Jens Juul, Smeets, P. A. M. & Full4Health consortium, F. C., 2021, In: NeuroImage. 240, 11 p., 118374.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Body weight and metabolic risk factors in patients with type 2 diabetes on a self-selected high-protein low-carbohydrate diet

    Alzahrani, A. H. A., Skytte, M. J., Samkani, A., Thomsen, M. N., Astrup, A., Ritz, C., Chabanova, E., Frystyk, J., Holst, Jens Juul, Thomsen, Henrik S., Madsbad, Sten, Haugaard, Steen Bendix, Krarup, T., Larsen, T. M. & Magkos, Faidon, 2021, In: European Journal of Nutrition. 60, 8, p. 4473-4482 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Can Metabolite and Hormone Profiles Provide a Rationale for Choosing Between Bariatric Procedures?

    Guimarães, M., Pereira, S. S., Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2021, In: Obesity Surgery. 31, p. 2174-2179

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Cerebral effects of glucagon-like peptide-1 receptor blockade before and after Roux-en-Y gastric bypass surgery in obese women: A proof-of-concept resting-state functional MRI study

    van Duinkerken, E., Bernardes, G., van Bloemendaal, L., Veltman, D. J., Barkhof, F., Mograbi, D. C., Gerdes, V. E. A., Deacon, Carolyn F., Holst, Jens Juul, Drent, M. L., Diamant, M., ten Kulve, J. & Ijzerman, R. G., 2021, In: Diabetes, Obesity and Metabolism. 23, 2, p. 415-424 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Combinatorial, additive and dose-dependent drug–microbiome associations

    Forslund, S. K., Chakaroun, R., Zimmermann-Kogadeeva, M., Markó, L., Aron-Wisnewsky, J., Nielsen, T., Moitinho-Silva, L., Schmidt, T. S. B., Falony, G., Vieira-Silva, S., Adriouch, S., Alves, R. J., Assmann, K., Bastard, J. P., Birkner, T., Caesar, R., Chilloux, J., Coelho, L. P., Fezeu, L., Galleron, N. & 23 others, Helft, G., Isnard, R., Ji, B., Kuhn, M., Le Chatelier, E., Myridakis, A., Olsson, L., Pons, N., Prifti, E., Quinquis, B., Roume, H., Lewinter, C., Søndertoft, N. B., Pedersen, H. K., Hansen, T. H., Hartmann, Bolette, Holst, Jens Juul, Hornbak, M., Jørgensen, Niklas Rye, Justesen, Johanne Marie, Krarup, N., Svendstrup, M. & The MetaCardis Consortium*, T. M. C., 2021, In: Nature. 600, p. 500-517 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Congenital Glucagon-like peptide-1 deficiency in the pathogenesis of protracted diarrhea in Mitchell Riley syndrome

    Nóbrega, S., Monteiro, M. P., Pereira-da-Silva, L., Pereira, S. S., Hartmann, Bolette, Holst, Jens Juul, Barbosa Silva, R. & Cordeiro-Ferreira, G., 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 4, p. 1084-1090

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Counterregulatory responses to postprandial hypoglycemia after Roux-en-Y gastric bypass

    Øhrstrøm, C. C., Hansen, D. L., Kielgast, U. L., Bergmann, M. L., Veedfald, Simon, Holst, Jens Juul & Worm, Dorte, 2021, In: Surgery for Obesity and Related Diseases. 17, 1, p. 55-63 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Development and evaluation of a glucagon sensitivity test

    Kjeldsen, Sasha Alexandra Sampson, Jensen, N. J., Nilsson, M. S. D., Nybing, J. D., Linden, F. H., Hogh-Schmidt, E., Boesen, Mikael Ploug, Madsbad, Sten, Vilstrup, H. V. A., Rashu, E. B., Gluud, Lise Lotte, Haugaard, Steen Bendix, Holst, Jens Juul, Rungby, Jørgen & Albrechtsen, Nicolai Jacob Wewer, 2021, In: Diabetologia. 64, SUPPL 1, p. 189-189 365.

    Research output: Contribution to journalConference abstract in journalResearch

  19. Published

    Dietary Fiber Is Essential to Maintain Intestinal Size, L-Cell Secretion, and Intestinal Integrity in Mice

    Dal, Jenna Elizabeth Hunt, Hartmann, Bolette, Schoonjans, K., Holst, Jens Juul & Kissow, Hannelouise, 2021, In: Frontiers in Endocrinology. 12, 10 p., 640602.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Differential effects of bile acids on the postprandial secretion of gut hormones: A randomized crossover study

    McGlone, E. R., Malallah, K., Cuenco, J., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vincent, R. P., Ling, C., Khan, O. A., Verma, S., Ahmed, A. R., Walters, J. R. F., Khoo, B., Bloom, S. R. & Tan, T. M. M., 2021, In: American Journal of Physiology - Endocrinology and Metabolism. 320, 4, p. E671-E679

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published
  22. Published

    Dose-dependent efficacy of the glucose-dependent insulinotropic polypeptide (GIP)receptor antagonistGIP(3-30)NH2 on GIP actions in humans

    Gasbjerg, Lærke Smidt, Bari, E. J., Stensen, S., Hoe, B., Lanng, A. R., Mathiesen, D. S., Christensen, Mikkel Bring, Hartmann, Bolette, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, 2021, In: Diabetes, Obesity and Metabolism. 23, 1, p. 68-74

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Effect of fecal microbiota transplantation combined with Mediterranean diet on insulin sensitivity in subjects with metabolic syndrome

    Koopen, A. M., Almeida, E. L., Attaye, I., Witjes, J. J., Rampanelli, E., Majait, S., Kemper, M., Levels, J. H. M., Schimmel, A. W. M., Herrema, H., Scheithauer, T. P. M., Frei, W., Dragsted, Lars Ove, Hartmann, Bolette, Holst, Jens Juul, O’Toole, P. W., Groen, A. K. & Nieuwdorp, M., 2021, In: Frontiers in Microbiology. 12, 15 p., 662159.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Effect of the natural sweetener xylitol on gut hormone secretion and gastric emptying in humans: A pilot dose-ranging study

    Meyer-Gerspach, A. C., Drewe, J., Verbeure, W., Le Roux, C. W., Dellatorre-Teixeira, L., Rehfeld, Jens Frederik, Holst, Jens Juul, Hartmann, Bolette, Tack, J., Peterli, R., Beglinger, C. & Wölnerhanssen, B. K., 2021, In: Nutrients. 13, 1, 21 p., 174.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Effects of Manipulating Circulating Bile Acid Concentrations on Postprandial GLP-1 Secretion and Glucose Metabolism After Roux-en-Y Gastric Bypass

    Jonsson, I., Bojsen-Moller, K. N., Kristiansen, V. B., Veedfald, Simon, Albrechtsen, Nicolai Jacob Wewer, Clausen, T. R., Kuhre, Rune Ehrenreich, Rehfeld, Jens Frederik, Holst, Jens Juul, Madsbad, Sten & Svane, M. S., 2021, In: Frontiers in Endocrinology. 12, 11 p., 681116.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Effects of a self-prepared carbohydrate-reduced high-protein diet on cardiovascular disease risk markers in patients with type 2 diabetes

    Alzahrani, A. H., Skytte, M. J., Samkani, A., Thomsen, M. N., Astrup, A., Ritz, C., Frystyk, J., Holst, Jens Juul, Madsbad, Sten, Haugaard, Steen Bendix, Krarup, T., Larsen, T. M. & Magkos, Faidon, 2021, In: Nutrients. 13, 5, 10 p., 1694.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Effects of a whey protein pre-meal on bone turnover in participants with and without type 2 diabetes - A post hoc analysis of a randomised, controlled, crossover trial

    Bjørnshave, A., Lykkeboe, S., Hartmann, Bolette, Holst, Jens Juul, Hermansen, K. & Starup-Linde, J., 2021, In: Diabetic Medicine. 38, 6, 9 p., e14471.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Effects of carbohydrate restriction on postprandial glucose metabolism, β-cell function, gut hormone secretion, and satiety in patients with type 2 diabetes

    Skytte, M. J., Samkani, A., Astrup, A., Frystyk, J., Rehfeld, Jens Frederik, Holst, Jens Juul, Madsbad, Sten, Burling, K., Fenger, M., Thomsen, M. N., Larsen, T. M., Krarup, T. & Haugaard, Steen Bendix, 2021, In: American Journal of Physiology: Endocrinology and Metabolism. 320, 1, p. E7-E18 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Effects of prebiotics on postprandial GLP-1, GLP-2 and glucose regulation in patients with type 2 diabetes: A randomised, double-blind, placebo-controlled crossover trial

    Birkeland, E., Gharagozlian, S., Gulseth, H. L., Birkeland, K. I., Hartmann, Bolette, Holst, Jens Juul, Holst, R. & Aas, A., 2021, In: Diabetic Medicine. 38, 10, 10 p., e14657.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Effects of whey protein and dietary fiber intake on insulin sensitivity, body composition, energy expenditure, blood pressure, and appetite in subjects with abdominal obesity

    Fuglsang-Nielsen, R., Rakvaag, E., Langdahl, B., Knudsen, K. E. B., Hartmann, Bolette, Holst, Jens Juul, Hermansen, K. & Gregersen, S., 2021, In: European Journal of Clinical Nutrition. 75, p. 611–619

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Exogenous secretin decreases ad libitum food intake and exhibits a biphasic effect on supraclavicular brown adipose tissue activity in healthy men

    Bentzen, M. J., Heimburger, S. M. N., Hartmann, Bolette, Holst, Jens Juul, Christensen, Mikkel Bring & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 211-211 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  32. Published

    Exploring the GLP-1-GLP-1R axis in porcine pancreas and gastrointestinal tract in vivo by ex vivo autoradiography

    Manell, E., Puuvuori, E., Svensson, A., Velikyan, I., Hulsart-Billström, G., Hedenqvist, P., Holst, Jens Juul, Jensen Waern, M. & Eriksson, O., 2021, In: B M J Open Diabetes Research & Care. 9, 10 p., e002083.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Factors associated with favorable changes in food preferences after bariatric surgery

    Nielsen, M. S., Christensen, Bodil Just, Ritz, C., Holm, Lotte, Lunn, Susanne, Tækker, L., Schmidt, J. B., Bredie, Wender, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Hilbert, A., le Roux, C. W. & Sjödin, Anders Mikael, 2021, In: Obesity Surgery. 31, 8, p. 3514-3524 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Fasting plasma GLP-1 associates with overweight/obesity and cardiometabolic risk factors in children and adolescents

    Stinson, Sara, Jonsson, Anna Elisabet, Lund, M. A. V., Frithioff-Bøjsøe, C., Holm, L. A., Pedersen, Oluf Borbye, Ängquist, Lars, Sørensen, Thorkild I.A., Holst, Jens Juul, Christiansen, M., Holm, Jens-Christian, Hartmann, Bolette & Hansen, Torben, 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 6, p. 1718-1727

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Follistatin secretion is enhanced by protein, but not glucose or fat ingestion in obese persons independently of previous gastric bypass surgery

    Bojsen-Møller, K. N., Svane, M. S., Jensen, Christian Zinck, Kjeldsen, Sasha Alexandra Sampson, Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer & Madsbad, Sten, 2021, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 320, 5, p. G753-G758

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    GIP receptor deletion in mice confers resistance to HFD-induced obesity via alterations in energy expenditure and adipose tissue lipid metabolism

    Boer, G. A., Keenan, S. N., Miotto, P. M., Holst, Jens Juul & Watt, M. J., 2021, In: American Journal of Physiology: Endocrinology and Metabolism. 320, 4, p. E835-E845 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    GLP-1 Val8: A Biased GLP-1R Agonist with Altered Binding Kinetics and Impaired Release of Pancreatic Hormones in Rats

    van der Velden, W. J. C., Smit, F. X., Christiansen, Charlotte Bayer, Møller, T. C., Hjortø, Gertrud Malene, Larsen, Olav, Schiellerup, S. P., Bräuner, Hans, Holst, Jens Juul, Hartmann, Bolette, Frimurer, Thomas Michael & Rosenkilde, Mette, 2021, In: ACS Pharmacology & Translational Science. 4, 1, p. 296-313 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    GLP-1 and Intestinal Diseases

    Dal, Jenna Elizabeth Hunt, Holst, Jens Juul, Jeppesen, Palle Bekker & Kissow, Hannelouise, 2021, In: Biomedicines. 9, 4, 14 p., 383.

    Research output: Contribution to journalReviewResearchpeer-review

  39. Published

    Gastric emptying of solutions containing the natural sweetener erythritol and effects on gut hormone secretion in humans: A pilot dose-ranging study

    Wolnerhanssen, B. K., Drewe, J., Verbeure, W., le Roux, C. W., Dellatorre-Teixeira, L., Rehfeld, Jens Frederik, Holst, Jens Juul, Hartmann, Bolette, Tack, J., Peterli, R., Beglinger, C. & Meyer-Gerspach, A. C., 2021, In: Diabetes, Obesity and Metabolism. 23, 6, p. 1311-1321

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Genome-wide association study of circulating levels of glucagon during an oral glucose tolerance test

    Jonsson, Anna Elisabet, Stinson, Sara, Torekov, Signe Sørensen, Clausen, Tine Dalsgaard, Færch, K., Kelstrup, Louise, Grarup, Niels, Mathiesen, Elisabeth, Damm, Peter, Witte, D. R., Jørgensen, M. E., Pedersen, Oluf Borbye, Holst, Jens Juul & Hansen, Torben, 2021, In: BMC Medical Genomics. 14, 7 p., 3.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Glucagon-Like Peptide-1 Is Associated With Systemic Inflammation in Pediatric Patients Treated With Hematopoietic Stem Cell Transplantation

    Sørum, Maria Ebbesen, Kissow, Hannelouise, Hartmann, Bolette, Kielsen, K., Sørensen, K., Stinson, Sara, Frithioff-Bojsoe, C., Fonvig, Cilius Esmann, Holm, Jens-Christian, Hansen, Torben, Holst, Jens Juul & Müller, K. G., 2021, In: Frontiers in Immunology. 12, 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Glucagonostatic Potency of GLP-1 in Patients with Type 2 Diabetes, in Patients with Type 1 Diabetes, and Healthy Control Subjects

    Bagger, J. I., Grøndahl, M., Lund, Asger Bach, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2021, In: Diabetes. 70, 4, p. 1347-1356

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Glucose-Dependent Insulinotropic Peptide in the High-Normal Range Is Associated With Increased Carotid Intima-Media Thickness

    Jujic, A., Nilsson, P. M., Atabaki-Pasdar, N., Dieden, A., Tuomi, T., Franks, P. W., Holst, Jens Juul, Torekov, Signe Sørensen, Ravassa, S., Diez, J., Persson, M., Ahlqvist, E., Melander, O., Gomez, M. F., Groop, L. & Magnusson, M., 2021, In: Diabetes Care. 44, 1, p. 224-230 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Glucose-dependent insulinotropic polypeptide (GIP) contributes to sitagliptin-mediated improvement of beta cell function in patients with type 2 diabetes

    Stensen, S., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Christensen, M. B. & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 95-95 179.

    Research output: Contribution to journalConference abstract in journalResearch

  45. Published

    Importance of endogenous GLP-1 and GIP for postprandial glucose tolerance after Roux-en-Y gastric bypass and sleeve gastrectomy surgery

    Hindso, M., Hedback, N., Moller, A., Svane, M. S., Martinussen, C., Jorgensen, N. B., Dirksen, C., Gasbjerg, Lærke Smidt, Kristiansen, V. B., Hartmann, Bolette, Rosenkilde, Mette, Holst, Jens Juul, Madsbad, Sten & Bojsen-Moller, K. N., 2021, In: Diabetologia. 64, SUPPL 1, p. 200-201 387.

    Research output: Contribution to journalConference abstract in journalResearch

  46. Published

    In patients with controlled acromegaly, indices of glucose homeostasis correlate with IGF-1 levels rather than with type of treatment

    Decock, A., Verroken, C., Van de Velde, F., Vilsbøll, Tina, Holst, Jens Juul, T’Sjoen, G. & Lapauw, B., 2021, In: Clinical Endocrinology. 95, 1, p. 65-73

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Increased glucagon sensitivity in totally pancreatectomised patients

    Rix, I., Lund, A., Garvey, Lene Heise, Owen, K., Hansen, C., van Hall, Gerrit, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 118-119 226.

    Research output: Contribution to journalConference abstract in journalResearch

  48. Published

    Intestinal Adaptation upon Chemotherapy-Induced Intestinal Injury in Mice Depends on GLP-2 Receptor Activation

    Billeschou, Anna, Dal, Jenna Elizabeth Hunt, Ghimire, A., Holst, Jens Juul & Kissow, Hannelouise, 2021, In: Biomedicines. 9, 1, 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Intestinal Growth in Glucagon Receptor Knockout Mice Is Not Associated With the Formation of AOM/DSS-Induced Tumors

    Dal, Jenna Elizabeth Hunt, Yassin, M., Olsen, Jørgen, Hartmann, Bolette, Holst, Jens Juul & Kissow, Hannelouise, 2021, In: Frontiers in Endocrinology. 12, 7 p., 695145.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published
  51. Published

    Liraglutide decreases postprandial fibroblast growth factor 19 and glucagon-like peptide 2, and increases postprandial cholecystokinin in individuals with obesity

    Bronden, A., Nerild, H. H., Nexoe-Larsen, C. C., Hellmann, P. H., Baekdal, M., Gether, I. M., Gillum, M. P., Hartmann, Bolette, Knudsen, L. B., Jacobsen, L. V., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina, Sonne, D. P. & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 94-94 177.

    Research output: Contribution to journalConference abstract in journalResearch

  52. Published

    Metformin stimulates intestinal glycolysis and lactate release: A single-dose study of metformin in patients with intrahepatic portosystemic stent

    Rittig, N., Aagaard, N. K., Sundelin, E., Villadsen, G. E., Sandahl, T. D., Holst, Jens Juul, Hartmann, Bolette, Brøsen, K., Grønbaek, H. & Jessen, N., 2021, In: Clinical Pharmacology and Therapeutics. 110, 5, p. 1329-1336

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Neprilysin Inhibition Increases Glucagon Levels in Humans and Mice With Potential Effects on Amino Acid Metabolism

    Kjeldsen, Sasha Alexandra Sampson, Hansen, L. H., Esser, N., Mongovin, S., Winther-Sørensen, Marie, Galsgaard, Katrine Douglas, Dal, Jenna Elizabeth Hunt, Kissow, Hannelouise, Ceutz, F. R., Terzic, D., Mark, P. D., Plomgaard, Peter Stendahl, Goetze, Jens P. , Goossens, G. H., Blaak, E. E., Deacon, Carolyn F., Rosenkilde, Mette, Zraika, S., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2021, In: Endocrine Research. 5, 9, 15 p., bvab084.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    No effects of dapagliflozin, metformin or exercise on plasma glucagon concentrations in individuals with prediabetes: A post hoc analysis from the randomized controlled PRE-D trial

    Clemmensen, K. K. B., Blond, M. B., Amadid, H., Bruhn, L., Vistisen, D., Karstoft, K., Persson, F., Ried-Larsen, M., Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Torekov, Signe Sørensen, Quist, J. S., Jorgensen, M. E. & Faerch, K., 2021, In: Diabetes, Obesity and Metabolism. 23, 2, p. 530-539

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Paracrine regulation of somatostatin secretion by insulin and glucagon in mouse pancreatic islets

    Svendsen, B. & Holst, Jens Juul, 2021, In: Diabetologia. 64, p. 142–151 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Parenteral nutrition impairs plasma bile acid and gut hormone responses to mixed meal testing in lean healthy men

    Meessen, E. C. E., Bakker, G. J., Nieuwdorp, M., Dallinga-Thie, G. M., Kemper, E. M., Olde Damink, S. W., Romijn, J. A., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag, Groen, A. K., Schaap, F. G. & Soeters, M. R., 2021, In: Clinical Nutrition. 40, 3, p. 1013-1021

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Pharmacokinetics of exogenous GIP(1-42) in C57Bl/6 mice; Extremely rapid degradation but marked variation between available assays

    Boer, G. A., Hartmann, Bolette & Holst, Jens Juul, 2021, In: Peptides. 136, 7 p., 170457.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Plasma GDF15 levels are similar between subjects after bariatric surgery and matched controls and are unaffected by meals

    Martinussen, C., Svane, M. S., Bojsen-Møller, K. N., Jensen, Christian Zinck, Kristiansen, V. B., Bookout, A. L., Jorgensen, S. B., Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Madsbad, Sten & Kuhre, Rune Ehrenreich, 2021, In: American Journal of Physiology: Endocrinology and Metabolism. p. E443-E452 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Plasma levels of glucagon but not GLP-1 are elevated in response to inflammation in humans

    Modrzynska, J., Klein, C. F., Iversen, Kasper, Bundgård, Henning, Hartmann, Bolette, Mose, M., Rittig, N., Møller, N., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2021, In: Endocrine Connections. 10, 2, p. 205-213 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Preserved postprandial suppression of bone turnover markers, despite increased fasting levels, in postmenopausal women

    Abildgaard, J., Ploug, Thorkil, Pedersen, Anette Tønnes, Eiken, P., Pedersen, Bente Klarlund, Holst, Jens Juul, Hartmann, Bolette & Lindegaard, Birgitte, 2021, In: Bone. 143, 8 p., 115612.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Reduced carbohydrate and increased protein and fat during weight loss improve the atherogenic lipid profile in type 2 diabetes

    Thomsen, M. N., Skytte, M. J., Samkani, A., Astrup, A., Frystyk, J., Chabanova, E., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Thomsen, Henrik S., Walzem, R. L., Krarup, T. & Haugaard, Steen Bendix, 2021, In: Diabetologia. 64, SUPPL 1, p. 60-60 109.

    Research output: Contribution to journalConference abstract in journalResearch

  62. Published

    Resistant starch combined with whey protein increases postprandial metabolism and lowers glucose and insulin responses in healthy adult men

    Mohr, A. E., Minicucci, O., Long, D., Miller, V. J., Keller, A., Sheridan, C., O’brien, G., Ward, E., Schuler, B., Connelly, S., Holst, Jens Juul, Astrup, A., He, F., Gentile, C. L. & Arciero, P. J., 2021, In: Foods. 10, 3, 17 p., 537.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Salivary ghrelin response to drinks varying in protein content and quantity and association with energy intake and appetite.

    Crabtree, D. R., Buosi, W., Fyfe, C. L., Horgan, G. W., Holst, Jens Juul, Johnstone, A. M. & Full4Health-study Group, F. G., 2021, In: Physiology and Behavior. 242, 113622.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Sitagliptin, a dipeptidyl peptidase-4 inhibitor, in patients with short bowel syndrome and colon in continuity: an open-label pilot study

    Naimi, R. M., Hvistendahl, M. K., Thomassen, L. M., Johnsen, H., Christiansen, Charlotte Bayer, Holst, Jens Juul, Hartmann, Bolette & Jeppesen, Palle Bekker, 2021, In: BMJ Open Gastroenterology. 8, 1, 10 p., e000604.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Six-day sc GIP infusion increases plasma NEFA without altering the adipose tissue transcriptome, GIPR levels or plasma markers of inflammation in patients with type 1 diabetes

    Heimburger, S. M. N., Hoe, B., Nielsen, C. N., Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Overgaard, J., Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Pyke, C., Christensen, M. B. & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 258-258 494.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  66. Published

    Subcutaneous GIP and GLP-2 inhibit nightly bone resorption in postmenopausal women: A preliminary study

    Skov-Jeppesen, Kirsa, Veedfald, Simon, Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2021, In: Bone. 152, 7 p., 116065.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    The Renal Extraction and the Natriuretic Action of GLP-1 in Humans Depend on Interaction With the GLP-1 Receptor

    Asmar, A., Cramon, P. K., Asmar, M., Simonsen, L., Sorensen, Charlotte Mehlin, Madsbad, Sten, Hartmann, Bolette, Holst, Jens Juul, Hovind, P., Jensen, B. L. & Bülow, J., 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 1, p. e11-e19 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    The antiresorptive effect of GIP, but not GLP-2, is preserved in patients with hypoparathyroidism - a randomized crossover study

    Skov-Jeppesen, Kirsa, Hepp, N., Oeke, J., Hansen, M. S., Jafari Kermani, Abbas, Svane, M. S., Balenga, N., Olson, J. A., Frost, M., Kassem, Moustapha Saad El-Deen, Madsbad, Sten, Jensen, Jens-Erik Beck, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2021, In: Journal of Bone and Mineral Research. 36, 8, p. 1448-1458 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    The effect of 6-day subcutaneous glucose-dependent insulinotropic polypeptide infusion on time in glycaemic range in patients with type 1 diabetes: a randomised, double-blind, placebo-controlled crossover trial

    Heimbürger, S. M. N., Hoe, B., Nielsen, C. N., Bergmann, N. C., Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Dejgaard, T. F., Christensen, Mikkel Bring & Knop, Filip Krag, 2021, In: Diabetologia. 64, p. 2425-2431

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    The effect of dietary carbohydrate restriction beyond weight loss on health-related quality of life and cognition

    Jensen, N. J., Wodschow, H. Z., fbg982, fbg982, Samkani, A., Astrup, A., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Miskowiak, Kamilla, Rungby, Jørgen, Haugaard, Steen Bendix & Thomsen, M. N., 2021, In: Diabetologia. 64, SUPPL 1, p. 62-63 114.

    Research output: Contribution to journalConference abstract in journalResearch

  71. Published

    The effect of melatonin on incretin hormones: results from experimental and randomized clinical studies

    Lauritzen, E. S., Støy, J., Bæch-Laursen, C., Grarup, Niels, Jessen, N., Hansen, Torben, Møller, N., Hartmann, Bolette, Holst, Jens Juul & Kampmann, U., 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 12, p. e5109-e5123 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    The effect of preceding glucose decline rate on low-dose glucagon efficacy in individuals with type 1 diabetes: A randomized crossover trial

    Laugesen, C., Schmidt, S., Holst, Jens Juul, Nørgaard, Kirsten & Ranjan, A. G., 2021, In: Diabetes, Obesity and Metabolism. 23, 4, p. 1057-1062 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    The glucose-lowering effect of the bile acid sequestrant sevelamer in patients with type 2 diabetes is not mediated by glucagon-like peptide 1

    Nerild, H. H., Brønden, Andreas, Haddouchi, A. E., Holst, Jens Juul, Sonne, D. P., Vilsbøll, Tina & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 217-217 422.

    Research output: Contribution to journalConference abstract in journalResearch

  74. Published

    The impact of acute fluctuations in plasma glucose on echocardiographic derived measures of systolic function in patients with type 1 diabetes

    Andreasen, C. R., Andersen, A., Haqelqvist, P. G., Abelin, K., Lauritsen, J. V., Jorgensen, P. G., Engberg, S., Faber, Jens, Holst, Jens Juul, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Diabetologia. 64, SUPPL 1, p. 135-136 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  75. Published

    The liver-alpha-cell axis after a mixed meal and during weight loss in type 2 diabetes

    Otten, J., Stomby, A., Waling, M., Chorell, E., Ryberg, M., Svensson, M., Holst, Jens Juul & Olsson, T., 2021, In: Endocrine Connections. 10, 9, p. 1101-1110

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    The liver–alpha cell axis associates with liver fat and insulin resistance: a validation study in women with non-steatotic liver fat levels

    Gar, C., Haschka, S. J., Kern-Matschilles, S., Rauch, B., Sacco, V., Prehn, C., Adamski, J., Seissler, J., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul & Lechner, A., 2021, In: Diabetologia. 64, 3, p. 512-520

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    The role of GLP-1 in postprandial glucose metabolism after bariatric surgery: a narrative review of human GLP-1 receptor antagonist studies

    Hindsø, M., Svane, M. S., Hedbäck, N., Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2021, In: Surgery for Obesity and Related Diseases. 17, 7, p. 1383-1391

    Research output: Contribution to journalReviewResearchpeer-review

  78. Published

    The role of GLP-1 in the postprandial effects of acarbose in type 2 diabetes

    Dalsgaard, N. B., Gasbjerg, Lærke Smidt, Hansen, L. S., Hansen, N. L., Stensen, S., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2021, In: European Journal of Endocrinology. 184, 3, p. 387-398 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    The role of incretins on insulin function and glucose homeostasis

    Holst, Jens Juul, Gasbjerg, Lærke Smidt & Rosenkilde, Mette, 2021, In: Endocrinology. 162, 7, 10 p., bqab065.

    Research output: Contribution to journalReviewResearchpeer-review

  80. Published

    Treatment of Type 2 Diabetes and Obesity on the Basis of the Incretin System: The 2021 Banting Medal for Scientific Achievement Award Lecture

    Holst, Jens Juul, 2021, In: Diabetes. 70, 11, p. 2468-2475 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Using a Reporter Mouse to Map Known and Novel Sites of GLP-1 Receptor Expression in Peripheral Tissues of Male Mice

    Andersen, Daniel Bjørklund, Grunddal, Kaare Villum, Pedersen, Jens, Kuhre, Rune Ehrenreich, Lund, M. L., Holst, Jens Juul & Ørskov, Cathrine, 2021, In: Endocrinology. 162, 3, bqaa246.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Voices: Insulin and beyond

    Roth, J., Ashcroft, F. M., Wollheim, C. B., Kieffer, T. J., Cherrington, A. D., Bergman, R. N., Taylor, R., Najjar, S. M., Pedersen, Oluf Borbye, Ellingsgaard, H., Holst, Jens Juul, Nauck, M. A., Kadowaki, T., Czech, M. P., Corvera, S., Saltiel, A. R., Corkey, B. E. & Atkinson, M. A., 2021, In: Cell Metabolism. 33, 4, p. 692-699 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    What Is an L-Cell and How Do We Study the Secretory Mechanisms of the L-Cell?

    Kuhre, Rune Ehrenreich, Deacon, Carolyn F., Holst, Jens Juul & Petersen, N., 2021, In: Frontiers in Endocrinology. 12, 19 p., 694284.

    Research output: Contribution to journalReviewResearchpeer-review

  84. Published

    What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists?

    Holst, Jens Juul, 2021, In: Cell Reports Medicine. 2, 5, 2 p., 100284.

    Research output: Contribution to journalComment/debateResearch

  85. Published

    What is Diabetes Remission?

    Holst, Jens Juul & Madsbad, Sten, 2021, In: Diabetes Therapy. 12, p. 641-646 6 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  86. Published

    β-Lactoglobulin Is Insulinotropic Compared with Casein and Whey Protein Ingestion during Catabolic Conditions in Men in a Double-Blinded Randomized Crossover Trial

    Mose, M., Møller, N., Jessen, N., Mikkelsen, U. R., Christensen, B., Rakvaag, E., Hartmann, Bolette, Holst, Jens Juul, Jørgensen, J. O. L. & Rittig, N., 2021, In: Journal of Nutrition. 151, 6, p. 1462-1472 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 4207