Jette Jacobsen
Associate Professor
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Waterborne Electrospinning of α-Lactalbumin Generates Tunable and Biocompatible Nanofibers for Drug Delivery
Stie, Mai Bay, Corezzi, M., Juncos Bombin, A. D., Ajalloueian, F., Attrill, E., Pagliara, S., Jacobsen, Jette, Chronakis, I. S., Nielsen, Hanne Mørck & Foderà, Vito, 2020, In: ACS Applied Nano Materials. 3, 2, p. 1910–1921Research output: Contribution to journal › Journal article › Research › peer-review
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Visualization of the penetration modifying mechanism of laurocapram by Mass Spectrometry Imaging in buccal drug delivery
Handler, A. M., Marxen, E., Jacobsen, Jette & Janfelt, Christian, 15 Jan 2019, In: European Journal of Pharmaceutical Sciences. 127, p. 276-281 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The role of citric acid in oral peptide and protein formulations: relationship between calcium chelation and proteolysis inhibition
Welling, S. H., Hubálek, F., Jacobsen, Jette, Brayden, D. J., Rahbek, U. L. & Buckley, S. T., Apr 2014, In: European Journal of Pharmaceutics and Biopharmaceutics. 86, 3, p. 544-51 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The physicochemical properties of preserved and preservative-free latanoprost eye drops and their impact on human conjunctival goblet cells
Müllertz, O. A. O., Nagstrup, Anne Hedengran, Mouhammad, Zaynab Ahmad, Freiberg, Josefine, Nagymihály, R., Jacobsen, Jette, Larsen, Susan Weng, Bair, J. A., Utheim, T. P., Dartt, D. A., Heegaard, Steffen, Petrovski, G. & Kolko, Miriam, 2022, In: Acta Ophthalmologica. 100, S267Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Tenacious and Lubricating Gels as Drug-Carrier and Body Fluids Substitutes
Vatne, K., Jacobsen, Jette, Baldursdottir, S. G., Pedersen, Anne Marie Lynge, Vilmann, Peter, Dalby, K. D. & Bar-Shalom, Daniel, 2 Nov 2014.Research output: Contribution to conference › Poster › Research › peer-review
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Tabletter med løse ender
Naelapaa, K., Mullertz, Anette , Jacobsen, Jette, Rømsing, J. & Bar-Shalom, Daniel, 2009, In: Lægemiddelforskning. p. 4-6Research output: Contribution to journal › Journal article › Research
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Tabletter med "løse ender" giver forsinket afgift af lægemiddelstof
Naelapaa, K., Mullertz, Anette , Jacobsen, Jette, Rømsing, J. & Bar-Shalom, Daniel, 2009, In: Lægemiddelforskning. p. 4-6 3 p.Research output: Contribution to journal › Journal article › Research
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Swelling of mucoadhesive electrospun chitosan/polyethylene oxide nanofibers facilitates adhesion to the sublingual mucosa
Stie, Mai Bay, Gätke, J. R., Wan, F., Chronakis, I. S., Jacobsen, Jette & Nielsen, Hanne Mørck, 15 Aug 2020, In: Carbohydrate Polymers. 242, 10 p., 116428.Research output: Contribution to journal › Journal article › Research › peer-review
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Safety and efficacy of sodium caprate in promoting oral drug absorption: from in vitro to the clinic
Maher, S., Leonard, T. W., Jacobsen, Jette & Brayden, D. J., 2009, In: Advanced Drug Delivery Reviews. p. 1427-1449Research output: Contribution to journal › Review › Research
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Process development for spray drying of sticky pharmaceuticals; case study of mucoad-hesive nicotine microparticles for compressed medicated chewing gum
Sander, C., Nielsen, H. S., Søgaard, S. R., Jensen, C. S., Yang, Mingshi, Jacobsen, Jette & Rantanen, Jukka, 2013, In: International Journal of Pharmaceutics. 452, 1-2, p. 434-437Research output: Contribution to journal › Journal article › Research › peer-review
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Predicting in vivo performance of fenofibrate amorphous solid dispersions using in vitro non-sink dissolution and dissolution permeation setup
Lentz, K. A., Plum, J., Steffansen, B., Arvidsson, P. O., Omkvist, D. H., Pedersen, A. J., Sennbro, C. J., Pedersen, G. P. & Jacobsen, Jette, 2021, In: International Journal of Pharmaceutics. 610, 8 p., 121174.Research output: Contribution to journal › Journal article › Research › peer-review
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Polymeric microcontainers improve oral bioavailability of furosemide
Nielsen, L. H., Melero, A., Keller, S. S., Jacobsen, Jette, Garrigues, T., Rades, Thomas, Mullertz, Anette & Boisen, A., 17 May 2016, In: International Journal of Pharmaceutics. 504, 1-2, p. 98-109 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Polymeric Lids for Microcontainers for Oral Protein Delivery
Mazzoni, C., Jacobsen, R. D., Mortensen, J., Jørgensen, J. R., Vaut, L., Jacobsen, Jette, Gundlach, C., Mullertz, Anette , Nielsen, L. H. & Boisen, A., 2019, In: Macromolecular Bioscience. 19, 5, 1900004.Research output: Contribution to journal › Journal article › Research › peer-review
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Polymer coated liposomes for use in the oral cavity - A study of the in vitro toxicity, effect on cell permeability and interaction with mucin
Klemetsrud, T., Kjøniksen, A., Hiorth, M., Jacobsen, Jette & Smistad, G., 2018, In: Journal of Liposome Research. 28, 1, p. 62–73 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Permeability Barriers for Nicotine and Mannitol in Porcine Buccal. Mucosa Studied by High-Resolution MALDI Mass Spectrometry Imaging
Marxen, E., Jacobsen, Jette, Hyrup, B. & Janfelt, Christian, 5 Feb 2018, In: Molecular Pharmaceutics. 15, 2, p. 519-526Research output: Contribution to journal › Journal article › Research › peer-review
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New lidocaine lozenge as topical anesthesia compared to lidocaine viscous oral solution before upper gastrointestinal endoscopy
Mogensen, S., Treldal, C., Feldager, E., Pulis, S., Jacobsen, Jette, Andersen, O. & Rasmussen, M., 2012, In: Local and Regional Anesthesia. 5, p. 17-22 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multivariate toxicity screening of liposomal formulations on a human buccal cell line
Smidstad, G., Jacobsen, Jette & Sande, S. A., 2007, In: Internation Journal of Pharmaceutics. 330, 1-2, p. 14-22Research output: Contribution to journal › Journal article › Research › peer-review
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Multi-material 3D printing of programmable and stretchable oromucosal patches for delivery of saquinavir
He, S., Radeke, C., Jacobsen, Jette, Lind, J. U. & Mu, Huiling, 2021, In: International Journal of Pharmaceutics. 610, 9 p., 121236.Research output: Contribution to journal › Journal article › Research › peer-review
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Mucoadhesive chitosan- and cellulose derivative-based nanofiber-on-foam-on-film system for non-invasive peptide delivery
Stie, Mai Bay, Öblom, H., Hansen, A. C. N., Jacobsen, Jette, Chronakis, I. S., Rantanen, Jukka, Nielsen, Hanne Mørck & Genina, Natalja, 2023, In: Carbohydrate Polymers. 303, 120429.Research output: Contribution to journal › Journal article › Research › peer-review
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Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging
Clitherow, K. H., Murdoch, C., Spain, S. G., Handler, A. M., Colley, H. E., Stie, Mai Bay, Nielsen, Hanne Mørck, Janfelt, Christian, Hatton, P. V. & Jacobsen, Jette, Sep 2019, In: Molecular Pharmaceutics. 16, 9, p. 3948-3956Research output: Contribution to journal › Journal article › Research › peer-review
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Mucoadhesive Electrospun Nanofiber-Based Hybrid System with Controlled and Unidirectional Release of Desmopressin
Stie, Mai Bay, Gätke, J. R., Chronakis, I. S., Jacobsen, Jette & Nielsen, Hanne Mørck, 2022, In: International Journal of Molecular Sciences. 23, 3, 9 p., 1458.Research output: Contribution to journal › Journal article › Research › peer-review
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Mucin dispersions as a model for the oromucosal mucus layer in in vitro and ex vivo buccal permeability studies of small molecules
Marxen, E., Mosgaard, M. D., Pedersen, Anne Marie Lynge & Jacobsen, Jette, 2017, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 121, p. 121-128Research output: Contribution to journal › Journal article › Research › peer-review
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Microenvironmental pH modifying films for buccal delivery of saquinavir: Effects of organic acids on pH and drug release in vitro
He, S., Østergaard, Jesper, Ashna, M., Nielsen, C. U., Jacobsen, Jette & Mu, Huiling, 2020, In: International Journal of Pharmaceutics. 585, 10 p., 119567.Research output: Contribution to journal › Journal article › Research › peer-review
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Medicated chewing gum
Jacobsen, Jette, Christrup, Lona Louring & Jensen, N., 2004, In: American Journal of Drug Delivery. 2, p. 75-88 14 p.Research output: Contribution to journal › Journal article › Research
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Kolliphor surfactants affect solubilization and bioavailability of fenofibrate. Studies of in vitro digestion and absorption in rats.
Berthelsen, R., Holm, R., Jacobsen, Jette, Kristensen, J., Abrahamsson, B. & Mullertz, Anette , 6 Apr 2015, In: Molecular Pharmaceutics. 12, 4, p. 1062-1071 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Investigating the effect of graphene oxide in chitosan/alginate-based foams on the release and antifungal activity of clotrimazole in vitro
Huang, Jianfei, Jacobsen, Jette, Genina, Natalja, Larsen, Susan Weng, Nielsen, Hanne Mørck, Mullertz, Anette & Mu, Huiling, 2022, In: European Journal of Pharmaceutical Sciences. 174, 9 p., 106204.Research output: Contribution to journal › Journal article › Research › peer-review
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Intestinal lymphatic transport of halofantrine in rats assessed using a chylomicron flow blocking approach: the influence of polysorbate 60 and 80
Lind, M. L., Jacobsen, Jette, Holm, R. & Mullertz, Anette , 2008, In: European Journal of Pharmaceutical Sciences. 35, 3, p. 211-218Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro, ex vivo and in vivo examination of buccal absorption of metoprolol with varying pH in TR146 cell culture, porcine buccal mucosa and Göttingen minipigs
Holm, R., Meng-Lund, E., Andersen, M. B., Jespersen, M. L., Karlsson, J., Garmer, M., Jørgensen, E. B. & Jacobsen, Jette, 13 May 2013, In: European Journal of Pharmaceutical Sciences. 49, 2, p. 117-124Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro and ex vivo evaluation of bilayered effervescent microenvironmental pH modifying buccal films with saquinavir
He, S., Nielsen, C. U., Mu, Huiling & Jacobsen, Jette, 2022, In: Journal of Drug Delivery Science and Technology. 78, 7 p., 103954.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of sodium dodecyl sulphate on the dissolution of poorly soluble drug into biorelevant medium from drug-surfactant discs
Madelung, P., Østergaard, Jesper, Bertelsen, P., Jørgensen, E. V., Jacobsen, Jette & Mullertz, Anette , 2 Mar 2014, In: International Journal of Pharmaceutics. 467, 1-2, p. 1-8Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of benzalkonium chloride-preserved and preservative-free latanoprost eye drops on cultured human conjunctival goblet cells upon acute exposure and differences in physicochemical properties of the eye drops
Mullertz, O., Nagstrup, Anne Hedengran, Mouhammad, Zaynab Ahmad, Freiberg, Josefine, Nagymihaly, R., Jacobsen, Jette, Larsen, Susan Weng, Bair, J., Utheim, T., Dartt, D. A., Heegaard, Steffen, Petrovski, G. & Kolko, Miriam, 2021, In: BMJ Open Ophthalmology. 6, 1, 7 p., 000892.Research output: Contribution to journal › Journal article › Research › peer-review
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Graphene oxide as a functional excipient in buccal films for delivery of clotrimazole: effect of molecular interactions on drug release and antifungal activity in vitro
Huang, Jianfei, Jacobsen, Jette, Larsen, Susan Weng, Genina, Natalja, van de Weert, Marco, Mullertz, Anette , Nielsen, Hanne Mørck & Mu, Huiling, 2020, In: International Journal of Pharmaceutics. 589, p. 1-9 119811.Research output: Contribution to journal › Journal article › Research › peer-review
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Generic benzalkonium chloride‐preserved travoprost eye drops are not identical to the branded polyquarternium‐1‐preserved travoprost eye drop: Effect on cultured human conjunctival goblet cells and their physicochemical properties
Nagstrup, Anne Hedengran, Freiberg, Josefine, Hansen, Pernille May, Jacobsen, Jette, Larsen, Susan Weng, Rønholt, Stine, Freude, Kristine, Boix‐lemonche, G., Petrovski, G., Heegaard, Steffen & Kolko, Miriam, 2022, In: Acta Ophthalmologica. 100, 7, p. 819-827Research output: Contribution to journal › Journal article › Research › peer-review
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Fed and fasted state gastro-intestinal in vitro lipolysis: In vitro in vivo relations of a conventional tablet, a SNEDDS and a solidified SNEDDS
Christophersen, P. C. B., Christiansen, M. L., Holm, R., Kristensen, J., Jacobsen, Jette, Abrahamsson, B. & Mullertz, Anette , 2014, In: European Journal of Pharmaceutical Sciences. 57, p. 232-239Research output: Contribution to journal › Journal article › Research › peer-review
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Fabrication of Mucoadhesive Buccal Films for Local Administration of Ketoprofen and Lidocaine Hydrochloride by Combining Fused Deposition Modeling and Inkjet Printing
Eleftheriadis, G. K., Monou, P. K., Bouropoulos, N., Bøtker, Johan Peter, Rantanen, Jukka, Jacobsen, Jette, Vizirianakis, I. S. & Fatouros, D. G., 2020, In: Journal of Pharmaceutical Sciences. 109, 9, p. 2757-2766Research output: Contribution to journal › Journal article › Research › peer-review
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Exploration of in vitro drug release testing methods for saquinavir microenvironmental pH modifying buccal films
He, S., Jacobsen, Jette, Nielsen, C. U., Genina, Natalja, Østergaard, Jesper & Mu, Huiling, 2021, In: European Journal of Pharmaceutical Sciences. 163, 10 p., 105867.Research output: Contribution to journal › Journal article › Research › peer-review
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Ex vivo - correlation of the absorption of metoprolol through human and porcine buccal mucosa at varying pH.
Meng-Lund, E., Marxen, E., Pedersen, Anne Marie Lynge, Mullertz, Anette , Holm, R., Hyrup, B. & Jacobsen, Jette, 4 Mar 2013.Research output: Contribution to conference › Poster › Research › peer-review
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Ex Vivo Correlation of the Permeability of Metoprolol Across Human and Porcine Buccal Mucosa
Meng-Lund, E., Marxen, E., Pedersen, Anne Marie Lynge, Mullertz, Anette , Hyrup, B., Holm, R. & Jacobsen, Jette, 13 May 2014, In: Journal of Pharmaceutical Sciences. 103, 7, p. 2053-2061 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evaluation of the use of Göttingen minipigs to predict food effects on the oral absorption of drugs in humans
Christiansen, M. L., Mullertz, Anette , Garmer, M., Kristensen, J., Jacobsen, Jette, Abrahamsson, B. & Holm, R., Jan 2015, In: Journal of Pharmaceutical Sciences. 104, 1, p. 135-143 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Electrospun α-lactalbumin nanofibers for site-specific and fast-onset delivery of nicotine in the oral cavity: an in vitro, ex vivo and tissue spatial distribution study
Kalouta, Kleopatra, Stie, Mai Bay, Janfelt, Christian, Chronakis, I. S., Jacobsen, Jette, Nielsen, Hanne Mørck & Foderà, Vito, 2020, In: Molecular Pharmaceutics. 17, 11, p. 4189-4200Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of polysorbate 80 on the in-vitro precipitation and oral bioavailability of halofantrine from polyethylene glycol 400 formulations in rats
Tønsberg, H., Holm, R., Boll, J. B., Jacobsen, Jette & Mullertz, Anette , 2009, In: Journal of Pharmacy and Pharmacology. 62, 1, p. 63-70Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of food intake and co-administration of placebo self-nanoemulsifying drug delivery systems on the absorption of cinnarizine in healthy human volunteers
Christiansen, M. L., Holm, R., Abrahamsson, B., Jacobsen, Jette, Kristensen, J., Andersen, Jens Rikardt & Mullertz, Anette , 2016, In: European Journal of Pharmaceutical Sciences. 84, p. 77-82 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of different surfactants in biorelevant medium on the secretion of a lipophilic compound in lipoproteins using Caco-2 cell culture
Karpf, D. M., Holm, R., Garafalo, C., Levy, E., Jacobsen, Jette & Mullertz, Anette , 2006, In: Journal of Pharmaceutical Sciences. 95, 1, p. 45-55 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of cryoprotectants for maintaining drug permeability barriers in porcine buccal mucosa
Marxen, E., Axelsen, M. C., Pedersen, Anne Marie Lynge & Jacobsen, Jette, 2016, In: International Journal of Pharmaceutics. 511, 1, p. 599-605 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of bile on the oral absorption of halofantrine in polyethylene glycol 400 and polysorbate 80 formulations dosed to bile duct cannulated rats
Tønsberg, H., Holm, R., Mu, Huiling, Boll, J. B., Jacobsen, Jette & Mullertz, Anette , 2011, In: Journal of Pharmacy and Pharmacology. 63, p. 817-824Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of a local anesthetic lozenge in relief of symptoms in burning mouth syndrome
Treldal, C., Jacobsen, C. B., Mogensen, S., Rasmussen, M., Jacobsen, Jette, Petersen, J., Pedersen, Anne Marie Lynge & Andersen, O., Mar 2016, In: Oral Diseases. 22, 2, p. 123-31 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of Permeation Enhancers on the Buccal Permeability of Nicotine: Ex vivo Transport Studies Complemented by MALDI MS Imaging
Marxen, E., Jin, L., Jacobsen, Jette, Janfelt, Christian, Hyrup, B. & Nicolazzo, J. A., 21 Feb 2018, In: Pharmaceutical Research. 35, 3, 12 p., 70.Research output: Contribution to journal › Journal article › Research › peer-review
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Dynamisk model for fordøjelse af lipidbaserede lægemidler i tarmen
Larsen, A., Fatourous, D., Jacobsen, Jette & Mullertz, Anette , 2008, In: Dansk Kemi. 89, 8, p. 30-33Research output: Contribution to journal › Journal article › Research
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Dynamisk model for fordøjelse af lipidbaserede lægemidler i tarmen
Fatouros, D., Larsen, A., Pedersen, B. L., Jacobsen, Jette & Mullertz, Anette , 2007, In: Lægemiddelforskning. p. 20-21Research output: Contribution to journal › Journal article › Communication
ID: 1298256
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185
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Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging
Research output: Contribution to journal › Journal article › Research › peer-review
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68
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Dissolution enhancement of griseofulvin from griseofulvin-sodium dodecyl sulfate discs investigated by UV imaging
Research output: Contribution to journal › Journal article › Research › peer-review
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Acids ‘generally recognized as safe’ affect morphology and biocompatibility of electrospun chitosan/polyethylene oxide nanofibers
Research output: Contribution to journal › Journal article › Research › peer-review
Published