Johan Peter Bøtker

Johan Peter Bøtker

Associate Professor

Associate professor

Image analysis and computer vision approaches for various pharmaceutical systems. Solid state analysis (thermal analysis, Raman spectroscopy, synchrotron SAXS and WAXS diffraction, powder X-ray diffraction) with MATLAB® / Python programming and multivariate methods for extraction of the chemical relevant data for subsequent analytical purposes.

Dissolution testing using conventional methods and custom produced setups by 3D printing thereby enabling characterization of the solid forms in relation to dissolution performance.

Acoustic treatment of data and inhaled drug delivery.

Processing of pharmaceutical solids (milling, hot-melt extrusion and 3D printing).

Selected publications

  1. Published

    Influence of temperature on solvent-mediated anhydrate-to-hydrate transformation kinetics

    Qu, H., Munk, T. P., Cornett, Claus, Wu, J., Bøtker, Johan Peter, Christensen, L. P., Rantanen, Jukka & Tian, F., 2011, In: Pharmaceutical Research. 28, 2, p. 364-373

    Research output: Contribution to journalJournal articlepeer-review

  2. Published

    Assessment of crystalline disorder in cryo-milled samples of indomethacin using atomic pair-wise distribution functions

    Bøtker, Johan Peter, Karmwar, P., Strachan, C. J., Cornett, Claus, Tian, F., Zujovic, Z., Rantanen, Jukka & Rades, Thomas, 2011, In: International Journal of Pharmaceutics. 417, 1-2, p. 112-119 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published

    Polymorphic form of piroxicam influences the performance of armorphous material prepared by ball-milling

    Naelapaa, K., Bøtker, Johan Peter, Veski, P., Rantanen, Jukka, Rades, Thomas & Kogermann, K., 2012, In: International Journal of Pharmaceutics. 429, 1-2, p. 69-77

    Research output: Contribution to journalJournal articlepeer-review

  4. Published

    Atomic pairwise distribution function analysis of the amorphous phase prepared by different manufacturing routes

    Bøtker, Johan Peter, Koradia, V., Rades, T., Rantanen, Jukka & Savolainen, M., 28 Aug 2012, In: Pharmaceutics. 4, 1, p. 93-103 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  5. Published

    Insights into the early dissolution events of amlodipine using UV imaging and Raman spectroscopy

    Bøtker, Johan Peter, Savolainen, M., Koradia, V., Tian, F., Rades, Thomas, Mullertz, Anette , Cornett, Claus, Rantanen, Jukka & Østergaard, Jesper, 2011, In: Molecular Pharmaceutics. 8, 4, p. 1372-1380 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    Investigations on the effect of different cooling rates on the stability of amorphous indomethacin

    Karmwar, P., Bøtker, Johan Peter, Graeser, K. A., Strachan, C. J., Rantanen, Jukka & Rades, T., 2011, In: European Journal of Pharmaceutical Sciences. 44, 3, p. 341-350

    Research output: Contribution to journalJournal articlepeer-review

  7. Published

    Structural elucidationof rapid solution-mediatedPhase transitions in pharmaceutical solids using in situ synchrotron SAXS/WAXS

    Bøtker, Johan Peter, Rades, Thomas, Rantanen, Jukka, Hawley, A. & Boyd, B. J., 1 Aug 2012, In: Molecular Pharmaceutics. 9, 9, p. 2787-2791

    Research output: Contribution to journalJournal articlepeer-review

  8. Published

    A new approach to dissolution testing by UV imaging and finite element simulations

    Bøtker, Johan Peter, Rantanen, Jukka, Rades, Thomas, Mullertz, Anette , Østergaard, Jesper & Jensen, H., 2013, In: Pharmaceutical Research. 30, 5, p. 1328-1337

    Research output: Contribution to journalJournal articlepeer-review

ID: 22365815