Stine Rønholt

Stine Rønholt

Tenure Track Assistant Professor

My research aim is cross-disciplinary focusing on the interface between physical chemistry, biophysics, biology and pharmaceutical sciences. I explore the barrier interactions between biological membranes, the skin and mucus barrier, and advanced drug delivery systems (DDS) or components hereof e.g., permeation enhancers and solid-state formulations intended for delivery of biopharmaceuticals. My research includes small as well as large molecules. I have a particular interest in how diseases in the barrier affects drug uptake and barrier interaction. By combining advanced biophysical techniques such as synchrotron X-ray and neutron scattering, rheology, rheo-microscopy, advanced microscopy (cryo-SEM and TEM) and thermal characterization with in vitro and in vivo models, I am currently developing a multimodal research platform to explore interactions between the skin barrier and delivery systems being deep eutectics and ionic liquids.

Selected publications

  1. Published

    Cell-penetrating peptides as carriers for transepithelial drug delivery in vitro

    Rønholt, Stine, Kristensen, Mie & Nielsen, Hanne Mørck, 2015, Cell-penetrating peptides : Methods and Protocols. Langel, Ü. (ed.). Vol. 1324. p. 261-277 17 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  2. Published

    The effect of butter grains on physical properties of butter-like emulsions

    Rønholt, Stine, Buldo, P., Mortensen, Kell, Andersen, U., Knudsen, J. C. & Wiking, L., 2014, In: Journal of Dairy Science. 97, 4, p. 1929-1938 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Metodeudvikling: Reologi til bestemmelse af fedtbaserede produkters materialeegenskaber

    Rønholt, Stine, Knudsen, J. C. & Mortensen, Kell, 2013, In: Dansk Kemi. 94, 11, p. 33-34 2 p.

    Research output: Contribution to journalJournal articleCommunication

  4. Published

    Fat crystallization in dairy products: Rheology and microstructure of fat crystals

    Rønholt, Stine, 2013, Department of Food Science, University of Copenhagen. 283 p.

    Research output: Book/ReportPh.D. thesis

  5. Published

    Effect of cream cooling rate and water content on butter microstructure during four weeks of storage

    Rønholt, Stine, Kirkensgaard, Jacob Judas Kain, Mortensen, Kell & Knudsen, J. C., 2014, In: Food Hydrocolloids. 34, p. 169-176 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The effect of capacity, rotational speed and storage on crystallization and rheological properties of puff pastry butter

    Rønholt, Stine, Kirkensgaard, Jacob Judas Kain, Høyer, K. F., Mortensen, Kell & Knudsen, J. C., 2014, In: Journal of the American Oil Chemists' Society. 91, 1, p. 29-38

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The effective factors on the structure of butter and other milk fat-based products

    Rønholt, Stine, Mortensen, Kell & Knudsen, J. C., 2013, In: Comprehensive Reviews in Food Science and Food Safety. 12, 5, p. 468-482 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Small deformation rheology for characterization of anhydrous milk fat/rapeseed oil samples

    Rønholt, Stine, Mortensen, Kell & Knudsen, J. C., 2014, In: Journal of Texture Studies. 45, 1, p. 20-29 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Polymorphism, microstructure and rheology of butter. Effects of cream heat treatment

    Rønholt, Stine, Kirkensgaard, Jacob Judas Kain, Pedersen, T. B., Mortensen, Kell & Knudsen, J. C., 2012, In: Food Chemistry. 135, 3, p. 1730-1739 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Microstructural and rheological characterization of fat crystals

    Rønholt, Stine, Mortensen, Kell, Hassenkam, Tue & Knudsen, J. C., 2010. 1 p.

    Research output: Contribution to conferencePosterResearch

  11. Published

    Calcipotriol delivery into the skin with PEGylated liposomes

    Knudsen, N. Ø., Rønholt, Stine, Salte, R. D., Jørgensen, Lene, Thormann, T., Basse, L. H., Hansen, J., Frøkjær, Sven & Foged, Camilla, 2012, In: European Journal of Pharmaceutics and Biopharmaceutics. 81, 3, p. 532-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Lipid-protein interactions in nanodiscs: how to enhance stability

    Wadsäter, M. H., Cardenas Gomez, M., Rønholt, Stine, Maric, S., Skar-Gislinge, Nicholas, Midtgaard, S. R., Arleth, Lise, Mortensen, Kell, Ryan, R. O. & Simonsen, J. B., 2012, In: Biophysical Journal. 102, 3, p. 236a 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  13. Published

    Fedtstruktur: innovation af smør og blandingsprodukter

    Rønholt, Stine, Knudsen, J. C., Mortensen, Kell, Kaufmann, N., Buldo, P., Wiking, L. & Andersen, U., 2012, In: Maelkeritidende. 6, p. 8-9 2 p.

    Research output: Contribution to journalJournal articleResearch

  14. Published

    Danmark kan lære meget af australske erfaringer med klinisk farmaci

    Rønholt, Stine, 2008, In: Pharma. 7, p. 32-34 3 p.

    Research output: Contribution to journalJournal articleCommunication

Selected activities

  1. 2014 AAPS Annual meeting and EXPO

    Rønholt, Stine (Speaker)

    2 Nov 20146 Nov 2014

    Activity: Participating in an event - typesParticipation in workshop, seminar, course

  2. COMPACT

    Rønholt, Stine (Speaker)

    3 Feb 20155 Feb 2015

    Activity: Participating in an event - typesParticipation in workshop, seminar, course

  3. EUPATI

    Rønholt, Stine (Speaker)

    1 Jan 2014 → …

    Activity: Participating in an event - typesParticipation in workshop, seminar, course

  4. Cell Penetrating Peptides

    Rønholt, Stine (Participant)

    7 Oct 201313 Oct 2013

    Activity: Participating in an event - typesParticipation in workshop, seminar, course

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