Ulrik Gether

Ulrik Gether

Head of Department, Professor


  1. 2020
  2. Published

    A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain

    Christensen, Nikolaj Riis, De Luca, M., Lever, M. B., Richner, M., Hansen, A. B., Noes-Holt, Gith, Jensen, K. L., Rathje, Mette, Jensen, Dennis Bo, Erlendsson, Simon, Bartling, Christian Reinhard Otto, Ammendrup-Johnsen, I., Pedersen, S. E., Schönauer, M., Nissen, K. B., Midtgaard, S. R., Teilum, Kaare, Arleth, Lise, Sørensen, Andreas Toft, Bach, Anders, Strømgaard, Kristian, Meehan, Claire Francesca, Vægter, C. B., Gether, Ulrik & Madsen, Kenneth Lindegaard, 2020, In : EMBO Molecular Medicine. 12, 6, 25 p., e11248.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    G protein-coupled receptor pharmacology-The next generation

    Bräuner-Osborne, Hans, Rosenkilde, Mette, Gether, Ulrik & Gloriam, David E., 2020, In : Basic & Clinical Pharmacology & Toxicology. 126, Supplement 6, p. 3-4 2 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  4. Published

    The mechanism of a high-affinity allosteric inhibitor of the serotonin transporter

    Plenge, P., Abramyan, A. M., Sørensen, G., Mork, A., Weikop, P., Gether, Ulrik, Bang-Andersen, B., Shi, L. & Loland, Claus Juul, 2020, In : Nature Communications. 11, 1, 12 p., 1491.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release

    Gotfryd, Kamil, Boesen, T., Mortensen, J. S., Khelashvili, G., Quick, M., Terry, D. S., Missel, Julie Winkel, LeVine, M. V., Gourdon, Pontus Emanuel, Blanchard, S. C., Javitch, J. A., Weinstein, H., Loland, Claus Juul, Nissen, P. & Gether, Ulrik, 2020, In : Nature Communications. 11, 1, 14 p., 1005.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2019
  7. Published

    Conformational dynamics of the human serotonin transporter during substrate and drug binding

    Möller, Ingvar Rúnar, Slivacka, M., Nielsen, A. K., Rasmussen, Søren Gøgsig Faarup, Gether, Ulrik, Loland, Claus Juul & Rand, Kasper Dyrberg, 11 Apr 2019, In : Nature Communications. 10, 1, 1687.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Autism-linked dopamine transporter mutation alters striatal dopamine neurotransmission and dopamine-dependent behaviors

    DiCarlo, G. E., Aguilar, J. I., Matthies, H. J. G., Harrison, F. E., Bundschuh, K. E., West, A., Hashemi, P., Herborg, Freja, Rickhag, M., Chen, H., Gether, Ulrik, Wallace, M. T. & Galli, A., 2019, In : Journal of Clinical Investigation. 129, 8, p. 3407-3419 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Chemogenetic Targeting of Dorsomedial Direct-pathway Striatal Projection Neurons Selectively Elicits Rotational Behavior in Mice

    Kønig, A. B., Ciriachi, C., Gether, Ulrik & Rickhag, Karl Mattias, 2019, In : Neuroscience. 401, p. 106-116

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Differential effects of chemogenetic inhibition on dopamine and norepinephrine neurons in the mouse 5-choice serial reaction time task

    Fitzpatrick, C. M., Runegaard, A. H., Christiansen, S. H., Hansen, Nikolaj Winther, Jørgensen, Søren Heide, McGirr, J. C., de Diego Ajenjo, Amaia, Sørensen, Andreas Toft, Perrier, Jean-Francois Marie, Petersen, A., Gether, Ulrik, Woldbye, David Paul Drucker & Andreasen T., Jesper, 2019, In : Progress in Neuro-Psychopharmacology & Biological Psychiatry. 90, 2, p. 264-276 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    G protein-coupled receptor signaling in VTA dopaminergic neurons bidirectionally regulates the acute locomotor response to amphetamine but does not affect behavioral sensitization

    Runegaard, A. H., Dencker, D., Wörtwein, Gitta & Gether, Ulrik, 2019, In : Neuropharmacology. 161, 107663.

    Research output: Contribution to journalReviewResearchpeer-review

  12. Published

    Increased vulnerability of nigral dopamine neurons after expansion of their axonal arborization size through D2 dopamine receptor conditional knockout

    Giguère, N., Delignat-Lavaud, B., Herborg, Freja, Voisin, A., Li, Yuan, Jacquemet, V., Anand-Srivastava, M., Gether, Ulrik, Giros, B. & Trudeau, L., 2019, In : PLOS Genetics. 15, 8, 26 p., e1008352.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Initial rewarding effects of cocaine and amphetamine assessed in a day using the single-exposure place preference protocol

    Runegaard, A. H., Jensen, K. L., Wörtwein, Gitta & Gether, Ulrik, 2019, In : European Journal of Neuroscience. 50, 3, p. 2156-2163 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Mechanisms of PDZ domain scaffold assembly illuminated by use of supported cell membrane sheets

    Erlendsson, Simon, Thorsen, Thor Seneca, Vauquelin, G., Ammendrup-Johnsen, I., Wirth, V., Martinez, Karen Laurence, Teilum, Kaare, Gether, Ulrik & Madsen, Kenneth Lindegaard, 2019, In : eLife. 8, p. 1-27 e39180.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Modulating Dopamine Signaling and Behavior with Chemogenetics: Concepts, Progress, and Challenges

    Runegaard, A. H., Fitzpatrick, C. M., Woldbye, David Paul Drucker, Andreasen T., Jesper, Sørensen, Andreas Toft & Gether, Ulrik, 2019, In : Pharmacological Reviews. 71, 2, p. 123-156 34 p.

    Research output: Contribution to journalReviewResearchpeer-review

  16. 2018
  17. Published

    An Amphipathic Helix Directs Cellular Membrane Curvature Sensing and Function of the BAR Domain Protein PICK1

    Jensen, Rasmus Herlo Beenfeldt, Lund, Viktor Karlovich, Lycas, Matthew Domenic, Jansen, A. M., Khelashvili, G., Andersen, Rita Chan, Bhatia, V., Pedersen, Thomas Skamris, Albornoz, P. B. C., Johner, N., Ammendrup-Johnsen, I., Christensen, Nikolaj Riis, Erlendsson, Simon, Stoklund, M., Larsen, J. B., Weinstein, H., Kjærulff, Ole, Stamou, Dimitrios, Gether, Ulrik & Madsen, Kenneth Lindegaard, 2018, In : Cell Reports. 23, 7, p. 2056-2069 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    An unsuspected role for organic cation transporter 3 in the actions of amphetamine

    Mayer, F. P., Schmid, D., Owens, W. A., Gould, G. G., Apuschkin, Mia, Kudlacek, O., Salzer, I., Boehm, S., Chiba, P., Williams, P. H., Wu, H., Gether, Ulrik, Koek, W., Daws, L. C. & Sitte, H. H., 2018, In : Neuropsychopharmacology. 43, p. 2408-2417 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published
  20. Published

    Neuropsychiatric disease-associated genetic variants of the dopamine transporter display heterogeneous molecular phenotypes

    Herborg, Freja, Andreassen, T. F., Berlin, F., Loland, Claus Juul & Gether, Ulrik, 2018, In : The Journal of Biological Chemistry. 293, 19, p. 7250-7262 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Obituary

    Brøsen, K., Simonsen, U. & Gether, Ulrik, 2018, In : Basic & clinical pharmacology & toxicology. 123, 5, p. 521-522 2 p.

    Research output: Contribution to journalComment/debateCommunication

  22. Published

    PICK1-Deficient Mice Exhibit Impaired Response to Cocaine and Dysregulated Dopamine Homeostasis

    Jensen, K. L., Sørensen, G., Dencker, D., Owens, W. A., Rahbek-Clemmensen, T., Brett Lever, M., Runegaard, A. H., Christensen, Nikolaj Riis, Weikop, P., Wörtwein, Gitta, Fink-Jensen, Anders, Madsen, Kenneth Lindegaard, Daws, L., Gether, Ulrik & Rickhag, Karl Mattias, 2018, In : eNeuro. 5, 3

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published
  24. 2017
  25. Published

    Chemogenetic Modulation of G Protein-Coupled Receptor Signalling in Visual Attention Research

    Jørgensen, Søren Heide, Fitzpatrick, C. M., Gether, Ulrik, Woldbye, David Paul Drucker & Sørensen, Andreas Toft, Nov 2017, In : Basic & Clinical Pharmacology & Toxicology. 121, 5, p. 373-381 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Assessment of Dopaminergic Homeostasis in Mice by Use of High-performance Liquid Chromatography Analysis and Synaptosomal Dopamine Uptake

    Jensen, K. L., Runegaard, A. H., Weikop, P., Gether, Ulrik & Rickhag, Karl Mattias, Sep 2017, In : Journal of Visualized Experiments. 127, 10 p., e56093.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Preserved dopaminergic homeostasis and dopamine-related behaviour in hemizygous TH-Cre mice

    Thomsen, A. H. R., Jensen, K. L., Fitzpatrick, C. M., Dencker, D., Weikop, P., Gether, Ulrik & Rickhag, Karl Mattias, Jan 2017, In : European Journal of Neuroscience. 45, 1, p. 121-128

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Direct assessment of substrate binding to the Neurotransmitter:Sodium Symporter LeuT by solid state NMR

    Erlendsson, Simon, Gotfryd, Kamil, Larsen, F. H., Mortensen, J. S., Geiger, M., van Rossum, B., Oschkinat, H., Gether, Ulrik, Teilum, Kaare & Loland, Claus Juul, 2017, In : eLife. 6, 9 p., e19314.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Investigating the molecular mechanism of positive and negative allosteric modulators in the calcium-sensing receptor dimer

    Jacobsen, S. E., Gether, Ulrik & Bräuner-Osborne, Hans, 2017, In : Scientific Reports. 7, 14 p., 46355.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Neurotransmitter Transporters: Structure, Function, and Drug Binding

    Loland, Claus Juul & Gether, Ulrik, 2017, Textbook of Drug Design and Discovery. Stromgaard, K., Krogsgaard-Larsen, P. & Madsen, U. (eds.). 5 ed. Boca Raton: CRC Press, p. 233-248 16 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  31. Published

    Subjective perception of cocaine reward in mice assessed by a single exposure place preference (sePP) paradigm

    Runegaard, A. H., Jensen, K. L., Dencker, D., Wörtwein, Gitta & Gether, Ulrik, 2017, In : Journal of Neuroscience Methods. 289, p. 85-92 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Super-resolution microscopy reveals functional organization of dopamine transporters into cholesterol and neuronal activity-dependent nanodomains

    Rahbek-Clemmensen, T., Lycas, Matthew Domenic, Erlendsson, Simon, Eriksen, J., Apuschkin, Mia, Vilhardt, Frederik, Jorgensen, T. N., Herborg, Freja & Gether, Ulrik, 2017, In : Nature Communications. 8, 14 p., 740.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    The GPRC6A Receptor displays Constitutive Internalization and Sorting to the Slow Recycling Pathway

    Jacobsen, S. E., Ammendrup-Johnsen, I., Jansen, A. M., Gether, Ulrik, Madsen, Kenneth Lindegaard & Bräuner-Osborne, Hans, 2017, In : The Journal of Biological Chemistry. 292, 17, p. 6910-6926

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Theory of Visual Attention (TVA) applied to mice in the 5-choice serial reaction time task

    Fitzpatrick, C. M., Caballero-Puntiverio, M., Gether, Ulrik, Habekost, Thomas, Bundesen, Claus, Vangkilde, Signe, Woldbye, David Paul Drucker, Andreasen T., Jesper & Petersen, Anders, 2017, In : Psychopharmacology. 234, 5, p. 845-855

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. 2016
  36. Published

    The Environment Shapes the Inner Vestibule of LeuT

    Sohail, A., Jayaraman, K., Venkatesan, S., Gotfryd, Kamil, Daerr, M., Gether, Ulrik, Loland, Claus Juul, Wanner, K. T., Freissmuth, M., Sitte, H. H., Sandtner, W. & Stockner, T., Nov 2016, In : PLoS Computational Biology. 12, 11, 24 p., e1005197.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Transition metal ion FRET uncovers K(+) regulation of a neurotransmitter/sodium symporter

    Billesbølle, C. B., Mortensen, J. S., Sohail, A., Schmidt, Solveig Gaarde, Shi, L., Sitte, H. H., Gether, Ulrik & Loland, Claus Juul, 28 Sep 2016, In : Nature Communications. 7, 12 p., 12755.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Conformational Dynamics on the Extracellular Side of LeuT Controlled by Na+ and K+ Ions and the Protonation State of Glu(290)

    Khelashvili, G., Schmidt, Solveig Gaarde, Shi, L., Javitch, J. A., Gether, Ulrik, Loland, Claus Juul & Weinstein, H., 16 Sep 2016, In : Journal of Biological Chemistry. 291, 38, p. 19786-19799

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    A kinome wide screen identifies novel kinases involved in regulation of monoamine transporter function

    Vuorenpää, A. E., Ammendrup-Johnsen, I., Jorgensen, T. N. & Gether, Ulrik, Sep 2016, In : Neurochemistry International. 98, p. 103-114

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Structural biology: Antidepressants at work

    Caron, M. G. & Gether, Ulrik, 21 Apr 2016, In : Nature. 532, p. 320-321 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  41. Published

    No effect of escitalopram versus placebo on brain-derived neurotrophic factor in healthy individuals: a randomised trial

    Knorr, Ulla Benedichte Søsted, Koefoed, P., Soendergaard, M. H. G., Vinberg, Maj, Gether, Ulrik, Gluud, C., Wetterslev, J., Winkel, P. & Kessing, Lars Vedel, Apr 2016, In : Acta Neuropsychiatrica. 28, 2, p. 101-109 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Differential Internalization Rates and Postendocytic Sorting of the Norepinephrine and Dopamine Transporters Are Controlled by Structural Elements in the N Termini

    Vuorenpää, A. E., Jørgensen, T. N., Newman, A. H., Madsen, Kenneth Lindegaard, Scheinin, M. & Gether, Ulrik, 11 Mar 2016, In : Journal of Biological Chemistry. 291, 11, p. 5634-5651 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Structure-activity relationship studies of citalopram derivatives: examining substituents conferring selectivity for the allosteric site in the serotonin transporter

    Larsen, M. A. B., Plenge, P., Andersen, J., Eildal, J. N. N., Kristensen, Anders Skov, Bøgesø, K. P., Gether, Ulrik, Strømgaard, Kristian, Bang-Andersen, B. & Loland, Claus Juul, Mar 2016, In : British Journal of Pharmacology. 173, 5, p. 925-936 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Effect of escitalopram versus placebo on GRα messenger RNA expression in peripheral blood cells of healthy individuals with a family history of depression - a secondary outcome analysis from the randomized AGENDA trial

    Knorr, Ulla Benedichte Søsted, Koefoed, P., Gluud, C., Wetterslev, J., Winkel, P., Gether, Ulrik, Vinberg, Maj & Kessing, Lars Vedel, 11 Jan 2016, In : Nordic Journal of Psychiatry. 70, 4, p. 297-302 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. 2015
  46. Published

    Substrate-induced Unlocking of the Inner Gate Determines the Catalytic Efficiency of a Neurotransmitter: Sodium Symporter

    Billesbolle, C. B., Kruger, M. B., Shi, L., Quick, M., Li, Z., Stolzenberg, S., Kniazeff, J., Gotfryd, Kamil, Mortensen, J. S., Javitch, J. A., Weinstein, H., Loland, Claus Juul & Gether, Ulrik, 30 Oct 2015, In : Journal of Biological Chemistry. 290, 44, p. 26725-26738 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Optogenetik bringer neurale mekanismer frem i lyset og kan blive en ny terapiform

    Axelsen, T. M., Navntoft, C. A. E., Christiansen, S. H., Dreyer, J. K., Sørensen, Jakob Balslev, Gether, Ulrik & Woldbye, David Paul Drucker, 17 Aug 2015, In : Ugeskrift for Laeger. 177, 34, p. 2-5 4 p., V06150501.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Functional regulation of amphetamine-induced efflux by CaMKII

    Sitte, H. H., Steinkellner, T., Montgomery, T. R., Hofmaier, T., Kudlacek, O., Yang, J., Jung, G., Lubec, G., Gether, Ulrik, Freissmuth, M. & Pollak, D. D., Aug 2015, In : Amino Acids. 47, 8, p. 1659-1659 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  49. Published

    Structure of dimeric and tetrameric complexes of the BAR domain protein PICK1 determined by small-angle X-Ray scattering

    Karlsen, M. L., Thorsen, Thor Seneca, Johner, N., Ammendrup-Johnsen, I., Erlendsson, Simon, Tian, X., Simonsen, J. B., Hoiberg-Nielsen, R., Christensen, N. M., Khelashvili, G., Streicher, W., Teilum, Kaare, Vestergaard, Bente, Weinstein, H., Gether, Ulrik, Arleth, Lise & Madsen, Kenneth Lindegaard, 7 Jul 2015, In : Structure. 23, 7, p. 1258-1270 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Akt-mediated regulation of antidepressant-sensitive serotonin transporter function, cell-surface expression and phosphorylation

    Rajamanickam, J., Annamalai, B., Rahbek-Clemmensen, T., Sundaramurthy, S., Gether, Ulrik, Jayanthi, L. D. & Ramamoorthy, S., 15 May 2015, In : Biochemical Journal. 468, 1, p. 177-190 14 p., BJ20140826.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Rare autism-associated variants implicate syntaxin 1 (STX1 R26Q) phosphorylation and the dopamine transporter (hDAT R51W) in dopamine neurotransmission and behaviors

    Cartier, E., Hamilton, P. J., Belovich, A. N., Shekar, A., Campbell, N. G., Saunders, C., Andreassen, T. F., Gether, Ulrik, Veenstra-Vanderweele, J., Sutcliffe, J. S., Ulery-Reynolds, P. G., Erreger, K., Matthies, H. J. G. & Galli, A., Feb 2015, In : EBioMedicine. 2, 2, p. 135-146 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    A novel dopamine transporter transgenic mouse line for identification and purification of midbrain dopaminergic neurons reveals midbrain heterogeneity

    Apuschkin, Mia, Stilling, S., Rahbek-Clemmensen, T., Sørensen, G., Fortin, G., Herborg, Freja, Eriksen, J., Trudeau, L., Egerod, Kristoffer Lihme, Gether, Ulrik & Rickhag, Karl Mattias, 2015, In : European Journal of Neuroscience. 42, 7, p. 2438-2454 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Amphetamine Action at the Cocaine- and Antidepressant-Sensitive Serotonin Transporter Is Modulated by αCaMKII

    Steinkellner, T., Montgomery, T. R., Hofmaier, T., Kudlacek, O., Yang, J., Rickhag, Karl Mattias, Jung, G., Lubec, G., Gether, Ulrik, Freissmuth, M. & Sitte, H. H., 2015, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 35, 21, p. 8258-8271 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Mechanism of the Association between Na+ Binding and Conformations at the Intracellular Gate in Neurotransmitter:Sodium Symporters

    Stolzenberg, S., Quick, M., Zhao, C., Gotfryd, Kamil, Khelashvili, G., Gether, Ulrik, Loland, Claus Juul, Javitch, J. A., Noskov, S., Weinstein, H. & Shi, L., 2015, In : The Journal of Biological Chemistry. 290, 22, p. 13992-4003 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. 2014
  56. Published

    In vivo amphetamine action is contingent on αCaMKII

    Steinkellner, T., Mus, L., Eisenrauch, B., Constantinescu, A., Leo, D., Konrad, L., Rickhag, Karl Mattias, Sørensen, G., Efimova, E. V., Kong, E., Willeit, M., Sotnikova, T. D., Kudlacek, O., Gether, Ulrik, Freissmuth, M., Pollak, D. D., Gainetdinov, R. R. & Sitte, H. H., Oct 2014, In : Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 39, 11, p. 2681-93 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    The BAR Domain Protein PICK1 Controls Vesicle Number and Size in Adrenal Chromaffin Cells

    da Silva Pinheiro, P. C., Jansen, A. M., de Wit, H., Tawfik, B., Madsen, Kenneth Lindegaard, Verhage, M., Gether, Ulrik & Sørensen, Jakob Balslev, 6 Aug 2014, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 34, 32, p. 10688-700 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    The second sodium site in the dopamine transporter controls cation permeability and is regulated by chloride

    Borre, L., Andreassen, T. F., Shi, L., Weinstein, H. & Gether, Ulrik, 25 Jul 2014, In : The Journal of Biological Chemistry. 289, p. 25764-25773 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Missense dopamine transporter mutations associate with adult parkinsonism and ADHD

    Herborg, Freja, Skjørringe, T., Yasmeen, S., Arends, N. V., Sahai, M. A., Erreger, K., Andreassen, T. F., Holy, M., Hamilton, P. J., Neergheen, V., Karlsborg, M., Newman, A. H., Pope, S., Heales, S. J. R., Friberg, L., Law, Ian, Pinborg, Lars Hageman, Sitte, H. H., Loland, Claus Juul, Shi, L., Weinstein, H., Galli, A., Hjermind, Lena Elisabeth, Møller, L. B. & Gether, Ulrik, 1 Jul 2014, In : The Journal of Clinical Investigation. 124, 7, p. 3107-20 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Serotonin-induced down-regulation of cell surface serotonin transporter

    Jørgensen, T. N., Christensen, P. M. & Gether, Ulrik, Jul 2014, In : Neurochemistry International. 73, p. 107-12 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    The serotonin transporter undergoes constitutive internalization and is primarily sorted to late endosomes and lysosomal degradation

    Rahbek-Clemmensen, T., Bay, T., Eriksen, J., Gether, Ulrik & Jørgensen, T. N., 27 Jun 2014, In : The Journal of Biological Chemistry. 289, p. 23004-23019 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Novel and high affinity fluorescent ligands for the serotonin transporter based on (s)-citalopram

    Kumar, V., Rahbek-Clemmensen, T., Billesbølle, C. B., Jorgensen, T. N., Gether, Ulrik & Newman, A. H., 12 Jun 2014, In : A C S Medicinal Chemistry Letters. 5, 6, p. 696-9 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Reply to Wilkinson et al. Concerning the use of pHluorin-tagged GluA2 as a reporter for NMDA-induced AMPA receptor recycling

    Rathje, Mette, Fang, H., Bachman, J. L., Gether, Ulrik, Huganir, R. L. & Madsen, Kenneth Lindegaard, 21 Jan 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 3, p. E305 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Protein interacting with C-kinase 1 (PICK1) binding promiscuity relies on unconventional PSD-95/Discs-Large/ZO-1 homology (PDZ) binding modes for nonclass II PDZ ligands

    Erlendsson, Simon, Rathje, Mette, Heiðarsson, P. O., Poulsen, F. M., Madsen, Kenneth Lindegaard, Teilum, Kaare & Gether, Ulrik, 2014, In : Journal of Biological Chemistry. 289, 36, p. 25327-25340 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. 2013
  66. Published

    De novo mutation in the dopamine transporter gene associates dopamine dysfunction with autism spectrum disorder

    Hamilton, P. J., Campbell, N. G., Sharma, S., Erreger, K., Herborg, Freja, Saunders, C., Belovich, A. N., NIH ARRA Autism Sequencing Consortium, N. A. A. S. C., Sahai, M. A., Cook, E. H., Gether, Ulrik, McHaourab, H. S., Matthies, H. J. G., Sutcliffe, J. S. & Galli, A., Dec 2013, In : Molecular Psychiatry. 18, 12, p. 1315-23 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Drosophila melanogaster: a novel animal model for the behavioral characterization of autism-associated mutations in the dopamine transporter gene

    Hamilton, P. J., Campbell, N. G., Sharma, S., Erreger, K., Herborg, Freja, Saunders, C., Belovich, A. N., Sahai, M. A., Cook, E. H., Gether, Ulrik, McHaourab, H. S., Matthies, H. J. G., Sutcliffe, J. S. & Galli, A., Dec 2013, In : Molecular Psychiatry. 18, 12, p. 1235

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Novel Tripod Amphiphiles for Membrane Protein Analysis

    Chae, P. S., Kruse, A. C., Gotfryd, Kamil, Rana, R. R., Cho, K. H., Rasmussen, Søren Gøgsig Faarup, Bae, H. E., Chandra, R., Gether, Ulrik, Guan, L., Kobilka, B. K., Loland, Claus Juul, Byrne, B. & Gellman, S. H., 2 Oct 2013, In : Chemistry: A European Journal. 19, 46

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Correction to "tandem facial amphiphiles for membrane protein stabilization"

    Chae, P. S., Gotfryd, Kamil, Pacyna, J., Miercke, L. J. W., Rasmussen, Søren Gøgsig Faarup, Robbins, R. A., Rana, R. R., Loland, Claus Juul, Kobilka, B., Stroud, R., Byrne, B., Gether, Ulrik & Gellman, S. H., 28 Aug 2013, In : Journal of the American Chemical Society. 135, 34, p. 12922 1 p.

    Research output: Contribution to journalJournal articleResearch

  70. Published

    AMPA receptor pHluorin-GluA2 reports NMDA receptor-induced intracellular acidification in hippocampal neurons

    Rathje, Mette, Fang, H., Bachman, J. L., Anggono, V., Gether, Ulrik, Huganir, R. L. & Madsen, Kenneth Lindegaard, 27 Aug 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 35, p. 14426-31 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    PICK1 deficiency impairs secretory vesicle biogenesis and leads to growth retardation and decreased glucose tolerance

    Holst, Birgitte, Madsen, Kenneth Lindegaard, Jansen, A. M., Jin, C., Rickhag, Karl Mattias, Lund, Viktor Karlovich, Jensen, M., Bhatia, V., Sørensen, G., Madsen, A. N., Xue, Z., Møller, S. K., Woldbye, David Paul Drucker, Qvortrup, Klaus, Huganir, R., Stamou, Dimitrios, Kjærulff, Ole & Gether, Ulrik, Apr 2013, In : P L o S Biology (Online). 11, 4, p. 1-25 25 p., e1001542.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study

    Chae, P. S., Rana, R. R., Gotfryd, Kamil, Rasmussen, Søren Gøgsig Faarup, Kruse, A. C., Cho, K. H., Capaldi, S., Carlsson, E., Kobilka, B., Loland, Claus Juul, Gether, Ulrik, Banerjee, S., Byrne, B., Lee, J. K. & Gellman, S. H., 21 Mar 2013, In : Chemical communications (Cambridge, England). 49, 23, p. 2287-9 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    A virtual high-throughput screening approach to the discovery of novel inhibitors of the bacterial leucine transporter, LeuT

    Simmons, K. J., Gotfryd, Kamil, Billesbølle, C. B., Loland, Claus Juul, Gether, Ulrik, Fishwick, C. W. G. & Johnson, A. P., Mar 2013, In : Molecular Membrane Biology. 30, 2, p. 184-94 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    A C-terminal PDZ domain-binding sequence is required for striatal distribution of the dopamine transporter

    Rickhag, Karl Mattias, Herborg, Freja, Sørensen, G., Strandfelt, K. N., Andresen, B., Gotfryd, Kamil, Madsen, Kenneth Lindegaard, Vestergaard-Klewe, I., Ammendrup-Johnsen, I., Eriksen, J., Newman, A. H., Füchtbauer, E., Gomeza, J., Woldbye, David Paul Drucker, Wörtwein, Gitta & Gether, Ulrik, 2013, In : Nature Communications. 4, p. 1-13 13 p., 1580.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Genome-wide association study of genetic variants in LPS-stimulated IL-6, IL-8, IL-10, IL-1ra and TNF-α cytokine response in a Danish Cohort

    Larsen, M. H., Albrechtsen, Anders, Thørner, L. W., Werge, T., Hansen, T., Gether, Ulrik, Haastrup, E. & Ullum, H., 2013, In : PLOS ONE. 8, 6, 6 p., e66262.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Membrane permeable C-terminal dopamine transporter peptides attenuate amphetamine-evoked dopamine release.

    Rickhag, Karl Mattias, Owens, W., Winkler, M., Strandfelt, K. N., Rathje, Mette, Sørensen, G., Andresen, B., Madsen, Kenneth Lindegaard, Nygaard Jørgensen, T., Wörtwein, Gitta, Woldbye, David Paul Drucker, Sitte, H. H., Daws, L. C. & Gether, Ulrik, 2013, In : Journal of Biological Chemistry. 288, p. 27534-44 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. 2012
  78. Published

    The effect of escitalopram versus placebo on perceived stress and salivary cortisol in healthy first-degree relatives of patients with depression-A randomised trial

    Knorr, Ulla Benedichte Søsted, Vinberg, Maj, Gether, Ulrik, Winkel, P., Gluud, C., Wetterslev, J. & Kessing, Lars Vedel, 30 Dec 2012, In : Psychiatry Research Review. 200, 2-3, p. 354-60 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Steric hindrance mutagenesis in the conserved extracellular vestibule impedes allosteric binding of antidepressants to the serotonin transporter

    Plenge, P., Shi, L., Beuming, T., Te, J., Newman, A. H., Weinstein, H., Gether, Ulrik & Loland, Claus Juul, 16 Nov 2012, In : The Journal of Biological Chemistry. 287, 47, p. 39316-26 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    The solute carrier 6 family of transporters

    Bröer, S. & Gether, Ulrik, 22 Aug 2012, In : British Journal of Pharmacology. 167, 2, p. 256-78 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    A New Class of Amphiphiles Bearing Rigid Hydrophobic Groups for Solubilization and Stabilization of Membrane Proteins

    Chae, P. S., Rasmussen, Søren Gøgsig Faarup, Rana, R. R., Gotfryd, Kamil, Kruse, A. C., Manglik, A., Cho, K. H., Nurva, S., Gether, Ulrik, Guan, L., Loland, Claus Juul, Byrne, B., Kobilka, B. K. & Gellman, S. H., 27 Jul 2012, In : Chemistry: A European Journal. 18, 31, p. 9485-90 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Protein interacting with C kinase 1 (PICK1) reduces reinsertion rates of interaction partners sorted to Rab11-dependent slow recycling pathway

    Madsen, Kenneth Lindegaard, Thorsen, Thor Seneca, Rahbek-Clemmensen, T., Eriksen, J. M. & Gether, Ulrik, 6 Apr 2012, In : The Journal of Biological Chemistry. 287, 15, p. 12293-308 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression

    Koefoed, P., Woldbye, David Paul Drucker, Hansen, T. V. O., Eplov, L. F., Christiansen, S. H. O., Mors, O., Kessing, Lars Vedel, Werge, Thomas, Kaipio, K., Pesonen, U., Fahmy, T., Mellerup, Erling Thyge, Jakobsen, K. D., Hansen, E. S., Knudsen, Gitte Moos, Bukh, J. D., Bock, C., Lindberg, C., Kristensen, A. S., Dam, Henrik, Nordentoft, Merete, Als, T. D., Wang, A. G., Gether, Ulrik, Rehfeld, Jens Frederik & Bolwig, T. G., 23 Mar 2012, In : Acta Neuropsychiatrica. 24, 2, p. 81-90 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Effect of chronic escitalopram versus placebo on personality traits in healthy first-degree relatives of patients with depression: a randomized trial

    Knorr, U., Vinberg, Maj, Mortensen, Erik Lykke, Winkel, P., Gluud, C., Wetterslev, J., Gether, Ulrik & Kessing, Lars Vedel, 29 Feb 2012, In : P L o S One. 7, 2, p. e31980 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Serine 77 in the PDZ domain of PICK1 is a protein kinase Cα phosphorylation site regulated by lipid membrane binding

    Ammendrup-Johnsen, I., Thorsen, Thor Seneca, Gether, Ulrik & Madsen, Kenneth Lindegaard, 17 Jan 2012, In : Biochemistry. 51, 2, p. 586-96 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. 2011
  87. Published

    SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation

    Kristensen, Anders Skov, Andersen, J., Jørgensen, T. N., Sørensen, L., Eriksen, J., Loland, Claus Juul, Strømgaard, Kristian & Gether, Ulrik, 1 Sep 2011, In : Pharmacological Reviews. 63, 3, p. 585-640 56 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    A fluorescence polarization based screening assay for identification of small molecule inhibitors of the PICK1 PDZ domain

    Thorsen, Thor Seneca, Madsen, Kenneth Lindegaard, Dyhring, T., Bach, Anders, Peters, D., Strømgaard, Kristian, Rønn, L. C. B. & Gether, Ulrik, 1 Aug 2011, In : Combinatorial Chemistry & High Throughput Screening. 14, 7, p. 590-600 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    The binding sites for benztropines and dopamine in the dopamine transporter overlap

    Jensen, H. B., Larsen, M. A. B., Mazier, S., Beuming, T., Weinstein, H., Shi, L., Loland, Claus Juul & Gether, Ulrik, 1 Jan 2011, In : Neuropharmacology. 60, 1, p. 182-90 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    A randomized trial of the effect of escitalopram versus placebo on cognitive function in healthy first-degree relatives of patients with depression

    Knorr, Ulla Benedichte Søsted, Vinberg, Maj, Gade, A., Winkel, P., Gluud, C., Wetterslev, J., Gether, Ulrik & Kessing, Lars Vedel, 2011, In : Therapeutic Advances in Psychopharmacology. 1, 5, p. 133-44 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Brain-derived neurotrophic factor (BDNF) enhances GABA transport by modulating the trafficking of GABA transporter-1 (GAT-1) from the plasma membrane of rat cortical astrocytes

    Vaz, S. H., Jørgensen, T. N., Cristóvão-Ferreira, S., Duflot, S., Ribeiro, J. A., Gether, Ulrik & Sebastião, A. M., 2011, In : Journal of Biological Chemistry. 286, 47, p. 40464-76 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Copy number variations in affective disorders and meta-analysis

    Olsen, L., Hansen, T., Djurovic, S., Haastrup, E., Albrecthsen, A., Hoeffding, L. K. E., Secher, A., Gustafsson, O., Jakobsen, K. D., Nielsen, Finn Cilius, Ullum, Henrik, Morken, G., Agartz, I., Melle, I., Gether, Ulrik, Andreassen, O. A. & Werge, Thomas, 2011, In : Psychiatric Genetics. 21, 6, p. 319-322 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Differences between early and late onset adult depression

    Drachmann Bukh, J., Bock, C., Vinberg, Maj, Gether, Ulrik & Kessing, Lars Vedel, 2011, In : Clinical Practice and Epidemiology in Mental Health. 7, p. 140-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Escitalopram and neuroendocrine response in healthy first-degree relatives to depressed patients--a randomized placebo-controlled trial

    Knorr, Ulla Benedichte Søsted, Vinberg, Maj, Hansen, A., Klose, M., Feldt-Rasmussen, Ulla, Hilsted, Linda, Hasselstrøm, J., Gether, Ulrik, Winkel, P., Gluud, C., Wetterslev, J. & Kessing, Lars Vedel, 2011, In : P L o S One. 6, 6, p. e21224 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. 2010
  96. Published

    Clinical utility of Standardised Assessment of Personality - Abbreviated Scale (SAPAS) among patients with first episode depression

    Bukh, J. D., Bock, C., Vinberg, Maj, Gether, Ulrik & Kessing, Lars Vedel, 1 Dec 2010, In : Journal of Affective Disorders. 127, 1-3, p. 199-202 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Tandem Facial Amphiphiles for Membrane Protein Stabilization

    Chae, P. S., Gotfryd, Kamil, Pacyna, J., Miercke, L. J. W., Rasmussen, Søren Gøgsig Faarup, Robbins, R. A., Rana, R. R., Loland, Claus Juul, Kobilka, B., Stroud, R., Byrne, B., Gether, Ulrik & Gellman, S. H., 1 Dec 2010, In : Journal of the American Chemical Society. 132, 47, p. 16750-2 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    The influence of comorbid personality disorder and neuroticism on treatment outcome in first episode depression

    Bock, C., Bukh, J. D., Vinberg, Maj, Gether, Ulrik, Kessing, Lars Vedel, Bock, C., Bukh, J. O. D., Vinberg, Maj, Kessing, Lars Vedel & Gether, U., 1 Jan 2010, In : Psychopathology. 43, 3, p. 197-204 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    BAR domains, amphipathic helices and membrane-anchored proteins use the same mechanism to sense membrane curvature

    Madsen, Kenneth Lindegaard, Bhatia, V. K., Gether, Ulrik & Stamou, Dimitrios, 2010, In : FEBS Letters. 584, 9, p. 1848-55 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    David versus Goliath

    Mollenhauer, J., Stamou, Dimitrios, Flyvbjerg, Allan, Wengel, J., Gether, Ulrik, Kjems, J., Bjørnholm, T. & Besenbacher, F., 2010, In : Nanomedicine: Nanotechnology, Biology and Medicine. 6, 4, p. 504-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Gender Differences among Patients with a Single Depressive Episode

    Bukh, J. D., Bock, C., Vinberg, Maj, Gether, Ulrik, Kessing, Lars Vedel, Bukh, J. O. D., Bock, C., Vinberg, Maj, Gether, U. & Kessing, Lars Vedel, 2010, In : Psychopathology. 43, 3, p. 159-169 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD

    Thorsen, Thor Seneca, Madsen, Kenneth Lindegaard, Rebola, N., Rathje, Mette, Anggono, V., Bach, Anders, Moreira, I. S., Stuhr-Hansen, N., Dyhring, T., Peters, D., Beuming, T., Huganir, R., Weinstein, H., Mulle, C., Strømgaard, Kristian, Rønn, L. C. B. & Gether, Ulrik, 2010, In : Proceedings of the National Academy of Science of the United States of America. 107, 1, p. 413-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins

    Chae, P. S., Rasmussen, Søren Gøgsig Faarup, Rana, R. R., Gotfryd, Kamil, Chandra, R., Goren, M. A., Kruse, A. C., Nurva, S., Loland, Claus Juul, Pierre, Y., Drew, D., Popot, J., Picot, D., Fox, B. G., Guan, L., Gether, Ulrik, Byrne, B., Kobilka, B. & Gellman, S. H., 2010, In : Nature Methods. 7, p. 1003-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Published

    Postendocytic sorting of constitutively internalized dopamine transporter in cell lines and dopaminergic neurons

    Eriksen, J., Bjørn-Yoshimoto, Walden, Jørgensen, T. N., Newman, A. H. & Gether, Ulrik, 2010, In : Journal of Biological Chemistry. 285, 35, p. 27289-301 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. Published

    Regulation of dopamine transporter function by protein-protein interactions: new discoveries and methodological challenges

    Eriksen, J., Jørgensen, T. N. & Gether, Ulrik, 2010, In : Journal of Neurochemistry. 113, 1, p. 27-41 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  106. Published

    Structure-activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1

    Bach, Anders, Stuhr-Hansen, N., Thorsen, Thor Seneca, Bork, N., Moreira, I. S., Frydenvang, Karla Andrea, Padrah, S., Christensen, Søren Brøgger, Madsen, Kenneth Lindegaard, Weinstein, H., Gether, Ulrik & Strømgaard, Kristian, 2010, In : Organic & Biomolecular Chemistry. 8, 19, p. 4281-4288 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  107. Published

    The N terminus of monoamine transporters is a lever required for the action of amphetamines

    Sucic, S., Dallinger, S., Zdrazil, B., Weissensteiner, R., Jørgensen, T. N., Holy, M., Kudlacek, O., Seidel, S., Cha, J. H., Gether, Ulrik, Newman, A. H., Ecker, G. F., Freissmuth, M. & Sitte, H. H., 2010, In : Journal of Biological Chemistry. 285, 14, p. 10924-38 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  108. 2009
  109. Published

    Do stressful life events predict medical treatment outcome in first episode of depression?

    Bock, C., Bukh, J. D., Vinberg, Maj, Gether, Ulrik & Kessing, Lars Vedel, Sep 2009, In : Social Psychiatry and Psychiatric Epidemiology. 44, 9, p. 752-60 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  110. Published

    A single nucleotide polymorphism in the human serotonin transporter introduces a new site for N-linked glycosylation

    Rasmussen, T. N., Plenge, P., Bay, T., Egebjerg, J. & Gether, Ulrik, 2009, In : Neuropharmacology. 57, 3, p. 287-94 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  111. Published

    Amphipathic motifs in BAR domains are essential for membrane curvature sensing

    Bhatia, V. K., Madsen, Kenneth Lindegaard, Bolinger, P., Kunding, A., Hedegård, Per, Gether, Ulrik & Stamou, Dimitrios, 2009, In : EMBO Journal. 28, 21, p. 3303-3314 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  112. Published

    An evaluation of the genetic-matched pair study design using genome-wide SNP data from the European population

    Lu, T. T., Lao, O., Nothnagel, M., Junge, O., Freitag-Wolf, S., Caliebe, A., Balascakova, M., Bertranpetit, J., Bindoff, L. A., Comas, D., Holmlund, G., Kouvatsi, A., Macek, M., Mollet, I., Nielsen, F., Parson, W., Palo, J., Ploski, R., Sajantila, A., Tagliabracci, A., Gether, Ulrik, Werge, Thomas, Rivadeneira, F., Hofman, A., Uitterlinden, A. G., Gieger, C., Wichmann, H., Ruether, A., Schreiber, S., Becker, C., Nürnberg, P., Nelson, M. R., Kayser, M. & Krawczak, M., 2009, In : European Journal of Human Genetics. 17, 7, p. 967-75 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  113. Published

    Do stressful life events predict medical treatment outcome in first episode of depression?

    Bock, C., Bukh, J. D., Vinberg, Maj, Gether, Ulrik, Kessing, Lars Vedel, Bock, C., Bukh, J. D., Vinberg, Maj, Gether, U. & Kessing, Lars Vedel, 2009, In : Social Psychiatry and Psychiatric Epidemiology. 44, 9, p. 752-60 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  114. Published

    Does bereavement-related first episode depression differ from other kinds of first depressions?

    Kessing, Lars Vedel, Bukh, J. D., Bock, C., Vinberg, Maj, Gether, Ulrik, Kessing, Lars Vedel, Bukh, J. D., Bock, C., Vinberg, Maj & Gether, U., 2009, In : Social Psychiatry and Psychiatric Epidemiology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  115. Published

    Elucidating Conformational Changes in the {gamma}-Aminobutyric Acid Transporter-1

    Meinild, A., Loo, D. D. F., Hansen, S. S., Gether, Ulrik & MacAulay, Nanna, 2009, In : Journal of Biological Chemistry. 284, 24, p. 16226-35 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  116. Published

    How curved membranes recruit amphipathic helices and protein anchoring motifs

    Hatzakis, Nikos, Bhatia, V. K., Larsen, J., Madsen, Kenneth Lindegaard, Bolinger, P., Kunding, A. H., Castillo Leon, J. J., Gether, Ulrik, Hedegård, Per & Stamou, Dimitrios, 2009, In : Nature Chemical Biology. 5, 11, p. 835-841 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  117. Published

    Interaction between genetic polymorphisms and stressful life events in first episode depression

    Bukh, J. D., Bock, C., Vinberg, Maj, Werge, Thomas, Gether, Ulrik, Kessing, Lars Vedel, Bukh, J. D., Bock, C., Vinberg, Maj, Werge, Thomas, Gether, U. & Kessing, Lars Vedel, 2009, In : Journal of Affective Disorders. 119, 1-3, p. 107-15 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  118. Published

    Introducing tetraCys motifs at two different sites results in a functional dopamine transporter

    Orun, O., Rasmussen, S. & Gether, Ulrik, 2009, In : Acta Biologica Hungarica. 60, 1, p. 15-25 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  119. Published

    Neurotransmitter transporters: structure and function

    Loland, Claus Juul & Gether, Ulrik, 2009, Texbook of Drug Design and Discovery. Madsen, U., Krogsgaard-Larsen, P. & Stromgaard, K. (eds.). 4 ed. Taylor & Francis

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducation

  120. Published

    No interactions between genetic polymorphisms and stressful life events on outcome of antidepressant treatment

    Bukh, J. D., Bock, C., Vinberg, Maj, Werge, Thomas, Gether, Ulrik, Kessing, Lars Vedel, Bukh, J. D., Bock, C., Vinberg, Maj, Werge, Thomas, Gether, U. & Kessing, Lars Vedel, 2009, In : European Neuropsychopharmacology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  121. Published

    PICK1 expression in the Drosophila central nervous system primarily occurs in the neuroendocrine system

    Jansen, A. M., Nässel, D. R., Madsen, Kenneth Lindegaard, Jung, A. G., Gether, Ulrik & Kjærulff, Ole, 2009, In : Journal of Comparative Neurology. 517, 3, p. 313-32 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  122. Published
  123. Published

    Validity of the diagnosis of a single depressive episode in a case register

    Bock, C., Bukh, J. D., Vinberg, Maj, Gether, Ulrik, Kessing, Lars Vedel, Bock, C., Bukh, J. D., Vinberg, Maj, Gether, U. & Kessing, Lars Vedel, 2009, In : Clinical Practice and Epidemiology in Mental Health. 5, p. 4

    Research output: Contribution to journalJournal articleResearchpeer-review

  124. Published

    Visualization of dopamine transporter trafficking in live neurons by use of fluorescent cocaine analogs

    Eriksen, J., Rasmussen, Søren Gøgsig Faarup, Jørgensen, T. N., Vaegter, C. B., Cha, J. H., Zou, M., Newman, A. H. & Gether, Ulrik, 2009, In : Journal of Neuroscience. 29, 21, p. 6794-808 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  125. 2008
  126. Published

    An intracellular interaction network regulates conformational transitions in the dopamine transporter.

    Kniazeff, J., Shi, L., Loland, Claus Juul, Javitch, J. A., Weinstein, H. & Gether, Ulrik, 2008, In : Journal of Biological Chemistry. 283, 25, p. 17691-701 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  127. Published

    Are life events prior to first episode of major depression a predictor of medical treatment outcome?

    Bock, C., Bukh, J. D., Christensen, M. V., Gether, Ulrik & Kessing, L. V., 2008, In : European Psychiatry. 23, Suppl. 2, p. S200-S200

    Research output: Contribution to journalJournal articleResearchpeer-review

  128. Published

    Correlation between genetic and geographic structure in Europe

    Lao, O., Lu, T. T., Nothnagel, M., Junge, O., Freitag-Wolf, S., Caliebe, A., Balascakova, M., Bertranpetit, J., Bindoff, L. A., Comas, D., Holmlund, G., Kouvatsi, A., Macek, M., Mollet, I., Parson, W., Palo, J., Ploski, R., Sajantila, A., Tagliabracci, A., Gether, Ulrik, Werge, Thomas, Rivadeneira, F., Hofman, A., Uitterlinden, A. G., Gieger, C., Wichmann, H., Rüther, A., Schreiber, S., Becker, C., Nürnberg, P., Nelson, M. R., Krawczak, M. & Kayser, M., 2008, In : Current Biology. 18, 16, p. 1241-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  129. Published

    Genetic Polymorphisms and the outcome of antidepressant Treatment

    Bukh, J. D., Bock, C., Christensen, M. V., Gether, Ulrik & Kessing, L. V., 2008, In : European Psychiatry. 23, p. S200-S200

    Research output: Contribution to journalJournal articleResearchpeer-review

  130. Published

    Glycine transporter dimers - Evidence for occurrence in the plasma membrane

    Bartholomaeus, I., Milan-Lobo, L., Nicke, A., Dutertre, S., Hastrup, H., Jha, A., Gether, Ulrik, Sitte, H. H., Betz, H. & Eulenburg, V., 2008, In : Journal of Biological Chemistry. 283, 16, p. 10978-10991 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  131. Published

    Glycine transporter dimers: evidence for occurrence in the plasma membrane

    Bartholomäus, I., Milan-Lobo, L., Nicke, A., Dutertre, S., Hastrup, H., Jha, A., Gether, Ulrik, Sitte, H. H., Betz, H. & Eulenburg, V., 2008, In : Journal of Biological Chemistry. 283, 16, p. 10978-91 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  132. Published

    Interaction between the glutamate transporter GLT1b and the synaptic PDZ domain protein PICK1

    Bassan, M., Liu, H., Madsen, Kenneth Lindegaard, Armsen, W., Zhou, J., Desilva, T., Chen, W., Paradise, A., Brasch, M. A., Staudinger, J., Gether, Ulrik, Irwin, N. & Rosenberg, P. A., 2008, In : European Journal of Neuroscience. 27, 1, p. 66-82 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  133. Published

    Membrane localization is critical for activation of the PICK1 BAR domain

    Madsen, Kenneth Lindegaard, Eriksen, J., Milan-Lobo, L., Han, D. S., Niv, M. Y., Ammendrup-Johnsen, I., Henriksen, U., Bhatia, V. K., Stamou, Dimitrios, Sitte, H. H., McMahon, H. T., Weinstein, H. & Gether, Ulrik, 2008, In : Traffic - International Journal of Intracellular Transport. 9, 8, p. 1327-43 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  134. Published

    Membrane localization is critical for activation of the PICK1BAR domain

    Madsen, K. L., Eriksen, J., Milan-Lobo, L., Han, D. S., Niv, M. Y., mmendrup-Johnsen, I., Henriksen, U., Bhatia, V. K., Stamou, Dimitrios, Sitte, H. H., McMahon, H. T., Weinstein, H. & Gether, Ulrik, 2008, In : Traffic - International Journal of Intracellular Transport. 9, 8, p. 1327-1343 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  135. Published

    Recruitment of beta-arrestin2 to the dopamine D2 receptor: insights into anti-psychotic and anti-parkinsonian drug receptor signaling

    Klewe, I. V., Nielsen, S. M., Tarpø, L., Urizar, E., Dipace, C., Javitch, J. A., Gether, Ulrik, Egebjerg, J. & Christensen, K. V., 2008, In : Neuropharmacology. 54, 8, p. 1215-1222 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  136. Published

    Reliability of clinical ICD-10 diagnoses among electroconvulsive therapy patients with chronic affective disorders

    Jakobsen, K. D., Hansen, T. F., Dam, H., Larsen, E. B., Gether, Ulrik & Werge, Thomas, 2008, In : European Journal of Psychiatry. 22, 3, p. 161-172 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  137. Published

    Syntaxin 1A interaction with the dopamine transporter promotes amphetamine-induced dopamine efflux

    Binda, F., Dipace, C., Bowton, E., Robertson, S. D., Lute, B. J., Fog, J. U., Zhang, M., Sen, N., Colbran, R. J., Gnegy, M. E., Gether, Ulrik, Javitch, J. A., Erreger, K. & Galli, A., 2008, In : Molecular Pharmacology. 74, 4, p. 1101-1108 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  138. Published

    The binding sites for cocaine and dopamine in the dopamine transporter overlap.

    Beuming, T., Kniazeff, J., Bergmann, M. L., Shi, L., Gracia, L., Raniszewska, K., Newman, A. H., Javitch, J. A., Weinstein, H., Gether, Ulrik & Loland, Claus Juul, 2008, In : Nature Neuroscience. 11, 7, p. 780-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  139. 2007
  140. Published

    Allosteric effects of R- and S-citalopram on the human 5-HT transporter: evidence for distinct high- and low-affinity binding sites

    Plenge, P., Gether, Ulrik & Rasmussen, Søren Gøgsig Faarup, 2007, In : European Journal of Pharmacology. 567, 1-2, p. 1-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  141. Published

    Membrane mobility and microdomain association of the dopamine transporter studied with fluorescence correlation spectroscopy and fluorescence recovery after photobleaching

    Adkins, E. M., Samuvel, D. J., Fog, J. U., Eriksen, J., Jayanthi, L. D., Vaegter, C. B., Ramamoorthy, S. & Gether, Ulrik, 2007, In : Biochemistry. 46, 37, p. 10484-97 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  142. Published

    Relationship between conformational changes in the dopamine transporter and cocaine-like subjective effects of uptake inhibitors.

    Loland, Claus Juul, Desai, R. I., Zou, M., Cao, J., Grundt, P., Gerstbrein, K., Sitte, H. H., Newman, A. H., Katz, J. L. & Gether, Ulrik, 2007, In : Molecular Pharmacology. 73, 3, p. 813-23 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  143. 2006
  144. Published

    Neurotransmitter transporters: molecular function of important drug targets

    Gether, Ulrik, Andersen, P. H., Larsson, O. M. & Schousboe, Arne, Jul 2006, In : Trends in Pharmacological Sciences. 27, 7, p. 375-83 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  145. Published

    Calmodulin kinase II interacts with the dopamine transporter C terminus to regulate amphetamine-induced reverse transport

    Fog, J. U., Khoshbouei, H., Holy, M., Owens, W. A., Vaegter, C. B., Sen, N., Nikandrova, Y., Bowton, E., McMahon, D. G., Colbran, R. J., Daws, L. C., Sitte, H. H., Javitch, J. A., Galli, A. & Gether, Ulrik, 2006, In : Neuron. 51, 4, p. 417-429 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  146. Published

    Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype

    Martinat, C., Bacci, J., Leete, T., Kim, J., Vanti, W. B., Newman, A. H., Cha, J. H., Gether, Ulrik, Wang, H. & Abeliovich, A., 2006, In : Proceedings of the National Academy of Science of the United States of America. 103, 8, p. 2874-2879 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  147. Published

    Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding (vol 279, pg 3228, 2004)

    Loland, C. J., Granas, C., Javitch, J. A. & Gether, Ulrik, 2006, In : Journal of Biological Chemistry. 281, 35, p. 25867-25867

    Research output: Contribution to journalJournal articleResearchpeer-review

  148. Published

    Molecular mechanisms of GPCR activation

    Rasmussen, Søren Gøgsig Faarup & Gether, Ulrik, 2006, G Protein-Coupled Receptors as Drug Targets: Analysis of Activation and Constitutive ActivityG Protein-Coupled Receptors as Drug Targets: Analysis of Activation and Constitutive Activity. 2006: Wiley, Vol. 24. p. 27-42 16 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  149. Published

    Neurotransmitter transporters: molecular function of important drug targets

    Gether, Ulrik, Andersen, P. H., Larsson, O. M. & Schousboe, A., 2006, In : Trends in Pharmacological Sciences. 27, 7, p. 375-383 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  150. Published

    Phosphorylation of the norepinephrine transporter at threonine 258 and serine 259 is linked to protein kinase C-mediated transporter internalization

    Jayanthi, L. D., Annamalai, B., Samuvel, D. J., Gether, Ulrik & Ramamoorthy, S., 2006, In : Journal of Biological Chemistry. 281, 33, p. 23326-40 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  151. Published

    Regulation of dopamine transporter trafficking by intracellular amphetamine.

    Kahlig, K. M., Lute, B. J., Wei, Y., Loland, Claus Juul, Gether, Ulrik, Javitch, J. A. & Galli, A., 2006, In : Molecular Pharmacology. 70, 2, p. 542-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  152. Published

    Zn2+ modulation of neurotransmitter transporters

    Nørgaard-Nielsen, K. & Gether, Ulrik, 2006, In : Handbook of Experimental Pharmacology. 175, p. 1-22 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  153. 2005
  154. Published

    Rhodamine-labeled 2beta-carbomethoxy-3beta-(3,4-dichlorophenyl)tropane analogues as high-affinity fluorescent probes for the dopamine transporter

    Cha, J. H., Zou, M., Adkins, E. M., Rasmussen, Søren Gøgsig Faarup, Loland, Claus Juul, Schoenenberger, B., Gether, Ulrik & Newman, A. H., 1 Dec 2005, In : Journal of Medicinal Chemistry. 48, 24, p. 7513-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  155. Published

    Identification of intra- and intermolecular disulfide bridges in the multidrug resistance transporter ABCG2

    Henriksen, U. B., Fog, J. U., Litman, Thomas & Gether, Ulrik, 4 Nov 2005, In : Journal of Biological Chemistry. 280, 44, p. 36926-34 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  156. Published

    Intramolecular cross-linking in a bacterial homolog of mammalian SLC6 neurotransmitter transporters suggests an evolutionary conserved role of transmembrane segments 7 and 8

    Kniazeff, J., Loland, Claus Juul, Goldberg, N., Quick, M., Das, S., Sitte, H. H., Javitch, J. A. & Gether, Ulrik, Nov 2005, In : Neuropharmacology. 49, 6, p. 715-23 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  157. Published

    Effect of Walker A mutation (K86M) on oligomerization and surface targeting of the multidrug resistance transporter ABCG2

    Henriksen, U. B., Gether, Ulrik & Litman, Thomas, 1 Apr 2005, In : Journal of Cell Science. 118, Pt 7, p. 1417-26 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  158. Published

    Purification and fluorescent labeling of the human serotonin transporter

    Rasmussen, Søren Gøgsig Faarup & Gether, Ulrik, 8 Mar 2005, In : Biochemistry. 44, 9, p. 3494-505 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  159. Published

    Molecular determinants for the complex binding specificity of the PDZ domain in PICK1

    Madsen, Kenneth Lindegaard, Beuming, T., Niv, M. Y., Chang, C., Dev, K. K., Weinstein, H. & Gether, Ulrik, 2005, In : Journal of Biological Chemistry. 280, 21, p. 20539-48 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  160. Published

    Molecular determinants for the complex binding specifity of the PDZ domain in PICK1

    Madsen, K. L., Beuming, T., Niv, M. Y., Chang, C. W., Dev, K. K., Weinstein, H. & Gether, Ulrik, 2005, In : Journal of Biological Chemistry. Vol. 280, no. 21, p. 20539-48

    Research output: Contribution to journalJournal articleResearchpeer-review

  161. 2004
  162. Published

    Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding

    Loland, Claus Juul, Grånäs, C., Javitch, J. A. & Gether, Ulrik, 30 Jan 2004, In : The Journal of Biological Chemistry. 279, 5, p. 3228-38 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  163. Published

    Insights from endogenous and engineered Zn2+-binding sites in monoanine transporters

    Loland, Claus Juul & Gether, Ulrik, 2004, Molecular Neuropharmacology: Strategies and Methods. p. 191-213

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  164. Published

    Intracellular residues in the dopamine transporter critical for conformational isomerization, molecular gating and cocaine binding

    Loland, Claus Juul, Granas, C., Javitc, J. & Gether, Ulrik, 2004, In : Journal of Biological Chemistry. Vol. 279, no. 5, p. 3228-38

    Research output: Contribution to journalJournal articleResearchpeer-review

  165. Published

    Surface targeting of the dopamine transporter involves discrete epitopes in the distal C terminus but does not require canonical PDZ doamin interactions

    Bjerggaard, C., Fog, J. U., Hastrup-Nielsen, H., Madsen, K., Loland, Claus Juul, Javitch, J. & Gether, Ulrik, 2004, In : Journal of Neuroscience. Vol. 24, no. 31, p. 7024-36

    Research output: Contribution to journalJournal articleResearchpeer-review

  166. Published

    Surface targeting of the dopamine transporter involves discrete epitopes in the distal C terminus but does not require canonical PDZ domain interactions

    Bjerggaard, C., Fog, J. U., Hastrup, H., Madsen, Kenneth Lindegaard, Loland, C. J., Javitch, J. A. & Gether, Ulrik, 2004, In : Journal of Neuroscience. 24, 31, p. 7024-36 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  167. Published

    Zinc Potentiates an Uncoupled Anion Conductance Associated with the Dopamine Transporter

    Meinild, A., Sitte, H. H. & Gether, Ulrik, 2004, In : Journal of Biological Chemistry. 279, 48, p. 49671-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  168. 2003
  169. Published

    Probing dopamine transporter structure and function by Zn2+-site engineering

    Loland, Claus Juul, Norgaard-Nielsen, K. & Gether, Ulrik, 31 Oct 2003, In : European Journal of Pharmacology. 479, 1-3, p. 187-97 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  170. Published

    Structural and functional probing of the biogenic amine transporters by fluorescence spectroscopy

    Rasmussen, Søren Gøgsig Faarup, Adkins, E. M., Carroll, F. I., Maresch, M. J. & Gether, Ulrik, 31 Oct 2003, In : European Journal of Pharmacology. 479, 1-3, p. 13-22 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  171. Published

    Evidence for distinct sodium-, dopamine-, and cocaine-dependent conformational changes in transmembrane segments 7 and 8 of the dopamine transporter

    Norregaard, L., Loland, Claus Juul & Gether, Ulrik, 15 Aug 2003, In : The Journal of Biological Chemistry. 278, 33, p. 30587-96 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  172. Published

    N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter internalization

    Granas, C., Ferrer, J., Loland, Claus Juul, Javitch, J. A. & Gether, Ulrik, 14 Feb 2003, In : The Journal of Biological Chemistry. 278, 7, p. 4990-5000 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  173. Published

    Evidence for distinct sodium-, dopamine-, cocaine-dependent conformational changes in transmembrane segments 7 and 8 of the dopamine

    Norregaard, L., Loland, Claus Juul & Gether, Ulrik, 2003, In : Journal of Biological Chemistry. Vol. 278 (33), p. 30587-96

    Research output: Contribution to journalJournal articleResearchpeer-review

  174. Published

    N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter interanalization

    Granas, C., Ferrer, J., Loland, Claus Juul, Javitch, J. A. & Gether, Ulrik, 2003, In : Journal of Biological Chemistry. Vol. 278 (7), p. 4990-5000

    Research output: Contribution to journalJournal articleResearchpeer-review

  175. Published

    Probing dopamine transporter structure and function y Zn2+ site engineering

    Loland, Claus Juul, Nørgaard-Nielsen, K. & Gether, Ulrik, 2003, In : European Journal of Pharmacology. Vol. 479, no 1-3, p. 187-97

    Research output: Contribution to journalReviewResearchpeer-review

  176. Published

    Residues in the extracellular loop 4 are critical for maintaining the conformational equilibrium of the gamma-aminobutyric acid transporter-1.

    MacAulay, Nanna, Meinild, A., Zeuthen, T. & Gether, Ulrik, 2003, In : Journal of Biological Chemistry. 278, 31, p. 28771-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  177. 2002
  178. Published

    Conformational basis for the Li(+)-induced leak current in the rat gamma-aminobutyric acid (GABA) transporter-1

    MacAulay, Nanna, Zeuthen, T. & Gether, Ulrik, 15 Oct 2002, In : Journal of Physiology. 544, Pt 2, p. 447-58 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  179. Published

    Zn(2+) site engineering at the oligomeric interface of the dopamine transporter

    Norgaard-Nielsen, K., Norregaard, L., Hastrup, H., Javitch, J. A. & Gether, Ulrik, 31 Jul 2002, In : FEBS letters. 524, 1-3, p. 87-91 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  180. Published

    The role of zinc ions in reverse transport mediated by monoamine transporters

    Scholze, P., Nørregaard, L., Singer, E. A., Freissmuth, M., Gether, Ulrik & Sitte, H. H., 14 Jun 2002, In : Journal of Biological Chemistry. 277, 24, p. 21505-13 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  181. Published

    Generation of an activating Zn(2+) switch in the dopamine transporter: mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle

    Loland, Claus Juul, Norregaard, L., Litman, Thomas & Gether, Ulrik, 5 Feb 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 3, p. 1683-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  182. Published

    Conformational basis for the Li+- induced leak current in the rat ¿- aminobutyric acid (GABA) transporter- 1

    MacAulay, Nanna, Zeuthen, T. & Gether, Ulrik, 2002, In : Journal of Physiology. 544, 2, p. 447-458

    Research output: Contribution to journalJournal articleResearchpeer-review

  183. Published

    Generation of an activating ZN(2+) switch in the dopamine transporter: Mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle

    Loland, Claus Juul, Norregaard, L., Litman, Thomas & Gether, Ulrik, 2002, In : Proceedings of the National Academy of Science of the United States of America. vol. 99(3), p. 1683-8

    Research output: Contribution to journalJournal articleResearchpeer-review

  184. Published

    Passive water and urea permeability of a human Na(+)-glutamate cotransporter expressed in Xenopus oocytes

    MacAulay, Nanna, Gether, Ulrik, Klærke, Dan Arne & Zeuthen, T., 2002, In : Journal of Physiology. 542, 3, p. 817-828 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  185. Published

    Structural basis for activation of G-protein-coupled receptors.

    Gether, Ulrik, Asmar, F., Meinild, A. K. & Rasmussen, Søren Gøgsig Faarup, 2002, In : Basic & Clinical Pharmacology & Toxicology. 91, 6, p. 304-12 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  186. Published

    The role of zine ions in reverse transport mediated by monoamine transporters

    Scholze, P., Norregaard, L., Singer, E. A., Freissmuth, M., Gether, Ulrik & Sitte, H. H., 2002, In : Journal of Biological Chemistry. 277, p. 21505-21513

    Research output: Contribution to journalJournal articleResearchpeer-review

  187. Published

    Understanding G-protein coupled receptors and their role in the CNS

    Rasmussen, Søren Gøgsig Faarup & Gether, Ulrik, 2002, Structural mechanics of GPCR activation. p. 43-62

    Research output: Chapter in Book/Report/Conference proceedingReport chapterResearch

  188. Published

    Use of fluorescence spectroscopy to study conformational changes in the beta 2-adrenoceptor

    Kobilka, B. K. & Gether, Ulrik, 2002, In : Methods in Enzymology. 343, 343, p. 170-182 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  189. Published

    Zn(2+) site engineering oat the oligomeric interface of the dopamine transporter

    Nørgaard-Nielsen, K., Norregaard, L., Hastrup-Nielsen, H., Javitch, J. A. & Gether, Ulrik, 2002, In : FEBS Letters. vol. 524(1-3), p. 87-91

    Research output: Contribution to journalJournal articleResearchpeer-review

  190. 2001
  191. Published

    Activation of the beta 2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6

    Ballesteros, J. A., Jensen, A. D., Liapakis, G., Rasmussen, Søren Gøgsig Faarup, Shi, L. & Gether, Ulrik, 2001, In : Journal of Biological Chemistry. 276 (31), p. 29171-29177

    Research output: Contribution to journalJournal articleResearchpeer-review

  192. Published

    Agonist-induced conformational changes at the cytoplasmic side of transmembrane segment 6 in the beta 2 adrenergic receptor mapped by site-selective fluorescent labeling

    Jensen, A. D., Guarnieri, F., Rasmussen, Søren Gøgsig Faarup, Asmar, F., Ballesteros, J. A. & Gether, Ulrik, 2001, In : Journal of Biological Chemistry. 276 (12), p. 9279-9290

    Research output: Contribution to journalJournal articleResearchpeer-review

  193. Published

    Biophysical characterization of the cocaine binding pocket in the serotonin transporter using a fluorescent cocaine analogue as a molecular reporter

    Rasmussen, Søren Gøgsig Faarup, Carroll, F. I., Maresch, M. J., Jensen, A. D. & Gether, Ulrik, 2001, In : Journal of Biological Chemistry. 276 (7), p. 4717-4723

    Research output: Contribution to journalJournal articleResearchpeer-review

  194. Published

    Delineating structure-function relationships in the dopamine transporter from natural and engineered Zn2+ binding sites

    Gether, Ulrik, Norregaard, L. & Loland, Claus Juul, 2001, In : Life Sciences. 68 (19-20), p. 2187-2198

    Research output: Contribution to journalJournal articleResearchpeer-review

  195. Published

    Engineered Zn(2+)switches in the gamma-aminobutyric acid (GABA) transporter-1. Differential effects on GABA uptake and currents

    MacAulay, Nanna, Bendahan, A., Loland, Claus Juul, Zeuthen, T., Kanner, B. I. & Gether, Ulrik, 2001, In : Journal of Biological Chemistry. 276, p. 40476-40485

    Research output: Contribution to journalJournal articleResearchpeer-review

  196. Published

    Functional differences between full and partial agonists: evidence for ligand-specific receptor conformations

    Seifert, R., Wenzel-Seifert, K., Gether, Ulrik & Kobilka, B. K., 2001, In : Journal of Pharmacology and Experimental Therapeutics. 297 (3), p. 1218-1226

    Research output: Contribution to journalJournal articleResearchpeer-review

  197. Published

    Structural probing of a microdomain in the dopamine transporter by engineering of artificial Zn2+ binding sites

    Norregaard, L., Visiers, I., Loland, Claus Juul, Ballesteros, J. A., Weinstein, H. & Gether, Ulrik, 2001, In : Biochemistry. 39 (51), p. 15836-15846

    Research output: Contribution to journalJournal articleResearchpeer-review

  198. Published

    Water transport by the human Na+-coupled glutamate cotransporter expressed in Xenopus oocytes

    MacAulay, Nanna, Gether, Ulrik, Klaerke, D. A. & Zeuthen, T., 2001, In : Journal of Physiology. 530 (Pt 3), p. 367-378

    Research output: Contribution to journalJournal articleResearchpeer-review

  199. 2000
  200. Published

    Structural probing of a microdomain in the dopamine transporter by engineering of artificial Zn2+ binding sites

    Norregaard, L., Visiers, I., Loland, Claus Juul, Ballesteros, J., Weinstein, H. & Gether, Ulrik, 26 Dec 2000, In : Biochemistry. 39, 51, p. 15836-15846 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  201. Published

    Assessing adrenergic receptor conformation using chemically reactive fluorescent probes

    Jensen Dam, A. & Gether, Ulrik, 2000, Methods in Molecular Biology, vol.126: Adrenergic Receptors Protocols. Totowa, NJ: Humana Press, p. 345-359

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  202. Published

    The effect of pH on ß2 adrenoceptor function

    Pejman, G., Hans, S., Roland, S., Tae Weon, L., Rasmussen, Søren Gøgsig Faarup, Gether, Ulrik & Kobilka, B. K., 2000, In : Journal of Biological Chemistry. 5, Vol. 275, p. 3121-3127

    Research output: Contribution to journalJournal articleResearchpeer-review

  203. Published

    Uncovering molecular mechanism involved in activation of G protein-coupled receptors

    Gether, Ulrik, 2000, In : Endocrine Reviews. 21(1), p. 90-113

    Research output: Contribution to journalJournal articleResearchpeer-review

  204. 1999
  205. Published

    Assessing adrenergic receptor using chemically reactive fluorescent probes

    Dam Jensen, A. & Gether, Ulrik, 1999, In Adrenergic Receptor Protocols, in the Methods for Molecular Biology. Humana Press, p. 345-361

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  206. Published

    Characterization of ligand-induced conformational states in the beta 2 adrenergic receptor

    Kobilka, B. K., Gether, Ulrik, Seifert, R., Lin, S. & Ghanouni, P., 1999, In : Journal of Receptors and Signal Transduction. 19, p. 293-300

    Research output: Contribution to journalJournal articleResearchpeer-review

  207. Published

    Defining proximity relationships in the tertiary structure of the dopamine transporter. Identification of a conserved glutamic acid as a third coordinate in the endogenous Zn(2+)-binding site.

    Loland, Claus Juul, Norregaard, L. & Gether, Ulrik, 1999, In : Journal of Biological Chemistry. 274, 52, p. 36928-34 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  208. Published

    Direct assessment of conformational changes in G protein coupled receptors using fluorescence spectroscopy

    Gether, Ulrik & Kobilka, B. K., 1999, In Signal Transduction - A practical Approach, in The practical Approach series, 2nd edition. Oxford: Oxford University Press, p. 01-17

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  209. Published

    Effects of guanine, inosine, and xanthine nucleotides on beta(2)-adrenergic receptor/G(s) interactions: evidence for multiple receptor conformations

    Seifert, R., Gether, Ulrik, Wenzel-Seifert, K. & Kobilka, B. K., 1999, In : Molecular Pharmacology. 56, p. 348-358

    Research output: Contribution to journalJournal articleResearchpeer-review

  210. Published

    Examining the efficiency of receptor/G-protein coupling with a cleavable beta2-adrenoceptor-Gsalpha fusion protein

    Seifert, R., Wenzel-Seifert, K., Gether, Ulrik, Lam, V. T. & Kobilka, B. K., 1999, In : European Journal of Biochemistry. 260, p. 661-666

    Research output: Contribution to journalJournal articleResearchpeer-review

  211. Published

    Fluorescence spectrosocpy analysis of conformational changes in the Β2 adrenergic receptor

    Gether, Ulrik, 1999, In Structure/Function of G-protein coupled receptors, in the Receptor Biochemistry and Methodology. New York: Wiley, p. 315-334

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  212. Published

    Mutation of a conserved aspartic acid in the Beta2 adrenergic recptor: constitutive activation, structural instability, and conformational rearrangement of transmembrane segment VI

    Rasmussen, Søren Gøgsig Faarup, Dam Jensen, A., Ghanouni, P., Liapakis, G., Javitch, J. & Gether, Ulrik, 1999, In : Molecular Pharmacology. 56, p. 175-184

    Research output: Contribution to journalJournal articleResearchpeer-review

  213. 1998
  214. Published

    Delineation of an endogenous zinc-binding site in the human dopamine transporter.

    Norregaard, L., Frederiksen, D., Nielsen, E. Ø. & Gether, Ulrik, 1998, In : EMBO Journal. 17, p. 4266-4273

    Research output: Contribution to journalJournal articleResearchpeer-review

  215. 1990
  216. Published

    Y1 receptors for neuropeptide Y are coupled to mobilization of intracellular calcium and inhibition of adenylate cyclase

    Aakerlund, L., Gether, Ulrik, Fuhlendorff, J., Schwartz, Thue W. & tml152, tml152, 1990, In : F E B S Letters. 260, 1, p. 73-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  217. Published

    [Leu31, Pro34]neuropeptide Y: a specific Y1 receptor agonist

    Fuhlendorff, J., Gether, Ulrik, Aakerlund, L., Langeland-Johansen, N., Thøgersen, H., Melberg, S. G., Olsen, U. B., tml152, tml152 & Schwartz, Thue W., 1990, In : Proceedings of the National Academy of Sciences of the United States of America. 87, 1, p. 182-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 11898