Oluf Borbye Pedersen

The Effect of Overweight and Obesity on Liver Biochemical Markers in Children and Adolescents

Johansen, M. J., Gade, J., Stender, Stefan, Frithioff-Bojsoe, C., Lund, M. A., Chabanova, E., Thomsen, Henrik S., Pedersen, Oluf Borbye, Fonvig, C. E., Hansen, Torben & Holm, Jens-Christian, 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 2, p. 430-442 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The Polygenic and Monogenic Basis of Blood Traits and Diseases

Vuckovic, D., Bao, E. L., Akbari, P., Lareau, C. A., Mousas, A., Jiang, T., Chen, M-H., Raffield, L. M., Tardaguila, M., Huffman, J. E., Ritchie, S. C., Megy, K., Ponstingl, H., Penkett, C. J., Albers, P. K., Wigdor, E. M., Sakaue, S., Moscati, A., Manansala, R., Lo, K. S. & 31 others, Qian, H., Akiyama, M., Bartz, T. M., Ben-Shlomo, Y., Beswick, A., Bork-Jensen, J., Bottinger, E. P., Brody, J. A., van Rooij, F. J. A., Chitrala, K. N., Wilson, P. W. F., Choquet, H., Danesh, J., Di Angelantonio, E., Dimou, N., Ding, J., Elliott, P., Esko, T., Evans, M. K., Felix, S. B., Floyd, J. S., Broer, L., Grarup, Niels, Guo, M. H., Guo, Q., Greinacher, A., Hansen, Torben, Linneberg, Allan René, Pedersen, Oluf Borbye, Loos, R. J. F. & VA Million Veteran Program, V. M. V. P., 2020, In: Cell. 182, 5, p. 1214-1231 29 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders

Andersen, M. K., Jørsboe, E., Skotte, L., Hanghøj, K., Sandholt, C. H., Moltke, I., Grarup, N., Kern, T., Mahendran, Y., Søborg, B., Bjerregaard, P., Larsen, C. V. L., Dahl-Petersen, I. K., Tiwari, H. K., Feenstra, B., Koch, A., Wiener, H. W., Hopkins, S. E., Pedersen, O., Melbye, M. & 4 others, Boyer, B. B., Jørgensen, M. E., Albrechtsen, Anders & Hansen, Torben, 2020, In: PLOS Genetics. 16, 1, 17 p., e1008544.

Research output: Contribution to journal › Journal article › Research › peer-review

The intestinal microbiome is a co-determinant of the postprandial plasma glucose response

Søndertoft, N. B., Vogt, J. K., Arumugam, Mani, Kristensen, M., Gøbel, R. J., Fan, Yong, Lyu, Liwei, Bahl, M. I., Eriksen, C., Ängquist, Lars, Frøkiær, Hanne, Hansen, T. H., Brix, Susanne, Nielsen, H. B., Hansen, Torben, Vestergaard, H., Gupta, R., Licht, T. R., Lauritzen, Lotte & Pedersen, Oluf Borbye, 2020, In: P L o S One. 15, 9, 23 p., e0238648.

Research output: Contribution to journal › Journal article › Research › peer-review

The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study

Koivula, R. W., Atabaki-Pasdar, N., Giordano, G. N., White, T., Adamski, J., Bell, J. D., Beulens, J., Brage, S., Brunak, S., De Masi, F., Dermitzakis, E. T., Forgie, I. M., Frost, G., Hansen, T., Hansen, T. H., Hattersley, A., Kokkola, T., Kurbasic, A., Laakso, M., Mari, A. & 15 others, McDonald, T. J., Pedersen, Oluf Borbye, Rutters, F., Schwenk, J. M., Teare, H. J. A., Thomas, E. L., Vinuela, A., Mahajan, A., McCarthy, M. I., Ruetten, H., Walker, M., Pearson, E., Pavo, I., Franks, P. W. & IMI-DIRECT consortium, I. C., 2020, In: Diabetologia. 63, 4, p. 744-756 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations

Chen, M-H., Raffield, L. M., Mousas, A., Sakaue, S., Huffman, J. E., Moscati, A., Trivedi, B., Jiang, T., Akbari, P., Vuckovic, D., Bao, E. L., Zhong, X., Manansala, R., Laplante, V., Chen, M., Lo, K. S., Qian, H., Lareau, C. A., Beaudoin, M., Hunt, K. A. & 31 others, Akiyama, M., Bartz, T. M., Ben-Shlomo, Y., Beswick, A., Bork-Jensen, J., Bottinger, E. P., Brody, J. A., van Rooij, F. J. A., Chitrala, K., Cho, K., Choquet, H., Correa, A., Danesh, J., Di Angelantonio, E., Dimou, N., Ding, J., Elliott, P., Esko, T., Evans, M. K., Floyd, J. S., Broer, L., Grarup, Niels, Guo, M. H., Greinacher, A., Haessler, J., Hansen, Torben, Howson, J. M. M., Linneberg, Allan René, Pedersen, Oluf Borbye, Loos, R. J. F. & VA Million Veteran Program, V. M. V. P., 2020, In: Cell. 182, 5, p. 1198-+ 30 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Whole blood co-expression modules associate with metabolic traits and type 2 diabetes: an IMI-DIRECT study

Gudmundsdottir, V., Pedersen, H. K., Mazzoni, G., Allin, K. H., Artati, A., Beulens, J. W., Banasik, K., Brorsson, C., Cederberg, H., Chabanova, E., De Masi, F., Elders, P. J., Forgie, I., Giordano, G. N., Grallert, H., Gupta, R., Haid, M., Hansen, T., Hansen, T. H., Hattersley, A. T. & 36 others, Heggie, A., Hong, M., Jones, A. G., Koivula, R., Kokkola, T., Laakso, M., Løngreen, P., Mahajan, A., Mari, A., McDonald, T. J., McEvoy, D., Musholt, P. B., Pavo, I., Prehn, C., Ruetten, H., Ridderstrale, M., Rutters, F., Sharma, S., Slieker, R. C., Syed, A., Tajes, J. F., Thomas, Cecilia Engel, Thomsen, Henrik S., Vangipurapu, J., Vestergaard, H., Vinuela, A., Wesolowska-Andersen, A., Walker, M., Adamski, J., Schwenk, J. M., McCarthy, M., Pearson, E., Dermitzakis, E., Franks, P. W., Pedersen, Oluf Borbye & Brunak, Søren, 2020, In: Genome Medicine. 12, 1, 17 p., 109.

Research output: Contribution to journal › Journal article › Research › peer-review

Urinary nucleic acid oxidation product levels show differential associations with pharmacological treatment in patients with type 2 diabetes

Kjaer, L. K., Cejvanovic, V., Henriksen, T., Hansen, Torben, Pedersen, Oluf Borbye, Christensen, C. K., Torp-Pedersen, C., Gerds, Thomas Alexander, Brandslund, I., Mandrup-Poulsen, Thomas & Poulsen, Henrik Enghusen, 3 Jun 2019, In: Free Radical Research. 53, 6, p. 694-703

Research output: Contribution to journal › Journal article › Research › peer-review

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

Broad Genomics Platform, B. G. P., Jun 2019, In: Nature. 570, 7759, p. 71-76 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial

Roager, H. M., Vogt, J. K., Kristensen, M. B., Hansen, L. B. S., Ibrügger, S., Mærkedahl, R. B., Bahl, M. I., Lind, M. V., Nielsen, R. L., Frøkiær, H., Gøbel, R. J., Landberg, R., Ross, A. B., Brix, S., Holck, J., Meyer, A. S., Sparholt, M. H., Christensen, A. F., Carvalho, V., Hartmann, B. & 18 others, Holst, Jens Juul, Rumessen, J. J., Linneberg, Allan René, Sicheritz-Pontén, T., Dalgaard, M. D., Blennow, Andreas, Frandsen, H. L., Villas-Bôas, S., Kristiansen, Karsten, drb459, drb459, Hansen, Torben, Ekstrøm, Claus Thorn, Ritz, C., Nielsen, H. B., Pedersen, Oluf Borbye, Gupta, R., Lauritzen, Lotte & Licht, T. R., Jan 2019, In: Gut. 68, 1, p. 83-93 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A cost analysis of intensified vs conventional multifactorial therapy in individuals with type 2 diabetes: a post hoc analysis of the Steno-2 study

Gæde, J., Oellgaard, J., Ibsen, R., Gæde, P., Nortoft, E., Parving, H., Kjellberg, J. & Pedersen, Oluf Borbye, 2019, In: Diabetologia. 62, 1, p. 147-155

Research output: Contribution to journal › Journal article › Research › peer-review

A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes: results from an exome-wide association study of albuminuria

Ahluwalia, T. S., Schulz, C-A., Waage, J., Skaaby, T., Sandholm, N., van Zuydam, N., Charmet, R., Bork-Jensen, J., Almgren, P., Thuesen, B. H., Bedin, M., Brandslund, I., Christensen, C. K., Linneberg, A., Ahlqvist, E., Groop, P-H., Hadjadj, S., Tregouet, D-A., Jorgensen, M. E., Grarup, N. & 9 others, Pedersen, Oluf Borbye, Simons, M., Groop, L., Orho-Melander, M., McCarthy, M. I., Melander, O., Rossing, Peter, Kilpeläinen, Tuomas O. & Hansen, Torben, 2019, In: Diabetologia. 62, 2, p. 292-305

Research output: Contribution to journal › Journal article › Research › peer-review

A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity

Bradfield, J. P., Vogelezang, S., Felix, J. F., Chesi, A., Helgeland, O., Horikoshi, M., Karhunen, V., Lowry, E., Cousminer, D. L., Ahluwalia, T. S., Thiering, E., Boh, E. T-H., Zafarmand, M. H., Vilor-Tejedor, N., Wang, C. A., Joro, R., Chen, Z., Gauderman, W. J., Pitkanen, N., Parra, E. J. & 79 others, Fernandez-Rhodes, L., Alyass, A., Monnereau, C., Curtin, J. A., Have, C. T., McCormack, S. E., Hollensted, M., Frithioff-Bojsoe, C., Valladares-Salgado, A., Peralta-Romero, J., Teo, Y., Standl, M., Leinonen, J. T., Holm, Jens-Christian, Peters, T., Vioque, J., Vrijheid, M., Simpson, A., Custovic, A., Vaudel, M., Canouil, M., Lindi, V., Atalay, M., Kahonen, M., Raitakari, O. T., van Schaik, B. D. C., Berkowitz, R. I., Cole, S. A., Voruganti, V. S., Wang, Y., Highland, H. M., Comuzzie, A. G., Butte, N. F., Justice, A. E., Gahagan, S., Blanco, E., Lehtimaki, T., Lakka, T. A., Hebebrand, J., Bonnefond, A., Grarup, Niels, Froguel, P., Lyytikainen, L., Cruz, M., Kobes, S., Hanson, R. L., Zemel, B. S., Hinney, A., Teo, K. K., Meyre, D., North, K. E., Gilliland, F. D., Bisgaard, H., Bustamante, M., Bønnelykke, Klaus, Pennell, C. E., Rivadeneira, F., Uitterlinden, A. G., Baier, L. J., Vrijkotte, T. G. M., Heinrich, J., Sørensen, Thorkild I.A., Saw, S., Pedersen, Oluf Borbye, Hansen, Torben, Eriksson, J., Widen, E., McCarthy, M. I., Njolstad, P. R., Power, C., Hypponen, E., Sebert, S., Brown, C. D., Jarvelin, M., Timpson, N. J., Johansson, S., Hakonarson, H., Jaddoe, V. W. V. & Grant, S. F. A., 2019, In: Human Molecular Genetics. 28, 19, p. 3327-3338

Research output: Contribution to journal › Journal article › Research › peer-review

ADAMTS9 regulates skeletal muscle insulin sensitivity through extracellular matrix alterations

Graae, A-S., Grarup, N., Ribel-Madsen, R., Lystbæk, S. H., Boesgaard, T., Staiger, H., Fritsche, A., Wellner, N., Sulek, K., Kjølby, M. F., Backe, M. B., Chubanava, S., Prats, C., Serup, A. K. L., Birk, J. B., Dubail, J., Gillberg, L., Vienberg, S. G., Nykjær, A., Kiens, B. & 10 others, Wojtaszewski, Jørgen F P, Larsen, Steen, Apte, S. S., Häring, H., Vaag, A., Zethelius, B., Pedersen, Oluf Borbye, Treebak, Jonas Thue, Hansen, Torben & Holst, Birgitte, 2019, In: Diabetes. 68, 3, p. 502-514

Research output: Contribution to journal › Journal article › Research › peer-review

Abdominal adiposity and cardiometabolic risk factors in children and adolescents: A Mendelian randomization analysis

Viitasalo, A., Schnurr, T. M., Pitkänen, N., Hollensted, M., Nielsen, T. R. H., Pahkala, K., Atalay, M., Lind, M. V., Heikkinen, S., Frithioff-Bøjsøe, C., Fonvig, C. E., Grarup, N., Kähönen, M., Carrasquilla, G. D., Larnkjær, A., Pedersen, O., Michaelsen, K. F., Lakka, T. A., Holm, J-C., Lehtimäki, T. & 3 others, Raitakari, O., Hansen, Torben & Kilpeläinen, Tuomas O., 2019, In: American Journal of Clinical Nutrition. 110, 5, p. 1079-1087 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Affective disorders and high familial risk of affective disorders associate with aberrant intestinal microbiota

Vinberg, Maj, Ottesen, N., Meluken, I., Sørensen, N., Pedersen, Oluf Borbye, Kessing, Lars Vedel & Miskowiak, Kamilla, 2019, In: European Neuropsychopharmacology. 29, Suppl. 1, p. S51 1 p.

Research output: Contribution to journal › Conference abstract in journal › Research

Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study

Huang, T., Wang, T., Zheng, Y., Ellervik, C., Li, X., Gao, M., Fang, Z., Chai, J-F., Ahluwalia, T. V. S., Wang, Y., Voortman, T., Noordam, R., Frazier-Wood, A., Scholz, M., Sonestedt, E., Akiyama, M., Dorajoo, R., Zhou, A., Kilpeläinen, T. O., Kleber, M. E. & 31 others, Crozier, S. R., Godfrey, K. M., Lemaitre, R., Felix, J. F., Shi, Y., Gupta, P., Khor, C., Lehtimäki, T., Wang, C. A., Tiesler, C. M. T., Thiering, E., Standl, M., Rzehak, P., Marouli, E., He, M., Lecoeur, C., Corella, D., Lai, C., Moreno, L. A., Pitkänen, N., Boreham, C. A., Zhang, T., Hansen, Torben, Sørensen, Thorkild I.A., Tjønneland, Anne, Overvad, K., Bisgaard, H., Pedersen, Oluf Borbye, Bønnelykke, Klaus, Rossing, Peter & BIRTH-GENE (BIG) Study Working Group, B. (. S. W. G., 2019, In: JAMA Network Open. 2, 9, 18 p., e1910915.

Research output: Contribution to journal › Journal article › Research › peer-review

Association of alcohol consumption with allergic disease and asthma: a multi-centre Mendelian randomization analysis

Skaaby, T., Kilpeläinen, T. O., Taylor, A. E., Mahendran, Y., Wong, A., Ahluwalia, T. S., Paternoster, L., Trompet, S., Stott, D. J., Flexeder, C., Zhou, A., Brusselle, G., Sajjad, A., Lahousse, L., Tiemeier, H., Have, C. T., Thuesen, B. H., Kårhus, L. L., Møllehave, L. T., Leth-Møller, K. B. & 27 others, Shabanzadeh, D. M., Gonzalez-Quintela, A., Power, C., Hyppönen, E., Kuh, D., Hardy, R., Meitinger, T., Jukema, J. W., Völker, U., Nauck, M., Völzke, H., Friedrich, N., Bonten, T. N., Noordam, R., Mook-Kanamori, D. O., Tolstrup, J. S., Taube, C., Peters, A., Grallert, H., Strauch, K., Schulz, H., Grarup, Niels, Hansen, Torben, Pedersen, Oluf Borbye, Burgess, S., Munafò, M. R. & Linneberg, Allan René, 2019, In: Addiction. 114, 2, p. 216-225 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association of genetic variants previously implicated in coronary artery disease with age at onset of coronary artery disease requiring revascularizations

Andersson, C., Krogager, M. L., Skals, R. K., Appel, E. V. R., Have, C. T., Grarup, N., Pedersen, O., Jeppesen, J. L., Pedersen, O. D., Dominguez, H., Dixen, U., Engstrøm, T., Tønder, N., Roden, D. M., Stender, S., Gislason, G. H., Enghusen-Poulsen, H., Hansen, T., Køber, L., Torp-Pedersen, C. & 1 others, Weeke, P. E., 2019, In: P L o S One. 14, 2, 12 p., e0211690.

Research output: Contribution to journal › Journal article › Research › peer-review

Associations between olfactory pathway gene methylation marks, obesity features and dietary intakes

Ramos-Lopez, O., Riezu-Boj, J. I., Milagro, F. I., Zulet, M. A., Santos, J. L., Martinez, J. A., Astrup, A., Larsen, T. M. & MENA Project, M. P., 2019, In: Genes & Nutrition. 14, 10 p., 11.

Research output: Contribution to journal › Journal article › Research › peer-review

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

Kraja, A. T., Liu, C., Fetterman, J. L., Graff, M., Have, C. T., Gu, C., Yanek, L. R., Feitosa, M. F., Arking, D. E., Chasman, D. I., Young, K., Ligthart, S., Hill, W. D., Weiss, S., Luan, J., Giulianini, F., Li-Gao, R., Hartwig, F. P., Lin, S. J., Wang, L. & 132 others, Richardson, T. G., Yao, J., Fernandez, E. P., Ghanbari, M., Wojczynski, M. K., Lee, W., Argos, M., Armasu, S. M., Barve, R. A., Ryan, K. A., An, P., Baranski, T. J., Bielinski, S. J., Bowden, D. W., Broeckel, U., Christensen, K., Chu, A. Y., Corley, J., Cox, S. R., Uitterlinden, A. G., Rivadeneira, F., Cropp, C. D., Daw, E. W., van Heemst, D., de las Fuentes, L., Gao, H., Tzoulaki, I., Ahluwalia, T. S., de Mutsert, R., Emery, L. S., Erzurumluoglu, A. M., Perry, J. A., Fu, M., Forouhi, N. G., Gu, Z., Hai, Y., Harris, S. E., Hemani, G., Hunt, S. C., Irvin, M. R., Jonsson, Anna Elisabet, Justice, A. E., Kernson, N. D., Larson, N. B., Lin, K., Love-Gregory, L. D., Mathias, R. A., Lee, J. H., Nauck, M., Noordam, R., Ong, K. K., Pankow, J., Patki, A., Pattie, A., Petersmann, A., Qi, Q., Ribel-Madsen, R., Rohde, R., Sandow, K., Schnurr, T. M., Sofer, T., Starr, J. M., Taylor, A. M., Teumer, A., Timpson, N. J., de Haan, H. G., Wang, Y., Weeke, P. E., Williams, C., Wu, H., Yang, W., Zeng, D., Witte, D. R., Weir, B. S., Wareham, N. J., drb459, drb459, Turner, S. T., Torp-Pedersen, C., Stergiakouli, E., Sheu, W. H., Rosendaal, F. R., Ikram, M. A., Franco, O. H., Ridker, P. M., Perls, T. T., Pedersen, Oluf Borbye, Nohr, E. A., Newman, A. B., Linneberg, Allan René, Langenberg, C., Kilpeläinen, Tuomas O., Kardia, S. L. R., Jørgensen, M. E., Jørgensen, T., Sørensen, Thorkild I.A., Homuth, G., Hansen, Torben, Goodarzi, M. O., Deary, I. J., Christensen, C., Chen, Y. I., Chakravarti, A., Brandslund, I., Bønnelykke, Klaus, Taylor, K. D., Wilson, J. G., Rodriguez, S., Davies, G., Horta, B. L., Thyagarajan, B., Rao, D. C., Grarup, Niels, Davila-Roman, V. G., Hudson, G., Guo, X., Arnett, D. K., Hayward, C., Vaidya, D., Mook-Kanamori, D. O., Tiwari, H. K., Levy, D., Loos, Ruth, Dehghan, A., Elliott, P., Malik, A. N., Scott, R. A., Becker, D. M., de Andrade, M., Province, M. A., Meigs, J. B., Rotter, J. I. & North, K. E., 2019, In: American Journal of Human Genetics. 104, 1, p. 112-138 27 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Beneficial impact of intensified multifactorial intervention on risk of stroke: outcome of 21 years of follow-up in the randomised Steno-2 Study

Gæde, P., Oellgaard, J., Kruuse, Christina Rostrup, Rossing, Peter, Parving, H. & Pedersen, Oluf Borbye, 2019, In: Diabetologia. 62, 9, p. 1575-1580

Research output: Contribution to journal › Journal article › Research › peer-review

Dairy Intake and Body Composition and Cardiometabolic Traits among Adults: Mendelian Randomization Analysis of 182041 Individuals from 18 Studies

Huang, T., Sun, D., Heianza, Y., Bergholdt, H. K. M., Gao, M., Fang, Z., Ding, M., Frazier-Wood, A. C., North, K. E., Marouli, E., Graff, M., Smith, C. E., Varbo, A., Lemaitre, R. N., Corella, D., Wang, C. A., Tjønneland, A., Overvad, K., Sørensen, T. I. A., Feitosa, M. F. & 36 others, Wojczynski, M. K., Kahonen, M., Mikkila, V., Bartz, T. M., Psaty, B. M., Siscovick, D. S., Danning, R. D., Dedoussis, G., Pedersen, Oluf Borbye, Hansen, Torben, Havulinna, A. S., Mannisto, S., Rotter, J. I., Sares-Jaske, L., Allison, M. A., Rich, S. S., Sorli, J. V., Coltell, O., Pennell, C. E., Eastwood, P., Ridker, P. M., Viikari, J., Raitakari, O., Lehtimaki, T., Helminen, M., Wang, Y., Deloukas, P., Knekt, P., Kanerva, N., Kilpeläinen, Tuomas O., Province, M. A., Mozaffarian, D., Chasman, D. I., Nordestgaard, B. G., Ellervik, Christina & Qi, L., 2019, In: Clinical Chemistry. 65, 6, p. 751-760 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Diabetic cats have decreased gut microbial diversity and a lack of butyrate producing bacteria

Kieler, Ida Nordang, Osto, M., Hugentobler, L., Puetz, Lara Christine, Gilbert, M Thomas P, Hansen, Torben, Pedersen, Oluf Borbye, Reusch, C. E., Zini, E., Lutz, T. A. & Bjørnvad, Charlotte Reinhard, 2019, In: Scientific Reports. 9, p. 1-13 13 p., 4822.

Research output: Contribution to journal › Journal article › Research › peer-review

Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium

Koivula, R. W., Forgie, I. M., Kurbasic, A., Viñuela, A., Heggie, A., Giordano, G. N., Hansen, T. H., Hudson, M., Koopman, A. D. M., Rutters, F., Siloaho, M., Allin, K. H., Brage, S., Brorsson, C. A., Dawed, A. Y., De Masi, F., Groves, C. J., Kokkola, T., Mahajan, A., Perry, M. H. & 31 others, Rauh, S. P., Ridderstråle, M., Teare, H. J. A., Thomas, E. L., Tura, A., drb459, drb459, White, T., Adamski, J., Bell, J. D., Beulens, J. W., Brunak, Søren, Dermitzakis, E. T., Froguel, P., Frost, G., Gupta, R., Hansen, Torben, Hattersley, A., Jablonka, B., Kaye, J., Laakso, M., McDonald, T. J., Pedersen, Oluf Borbye, Schwenk, J. M., Pavo, I., Mari, A., McCarthy, M. I., Ruetten, H., Walker, M., Pearson, E., Franks, P. W. & IMI-DIRECT consortium, I. C., 2019, In: Diabetologia. 62, 9, p. 1601-1615

Research output: Contribution to journal › Journal article › Research › peer-review

Does genetic predisposition to higher fat expandability attenuate the impact of weight gain on cardiometabolic risk?

Carrasquilla, Germán D., Linneberg, Allan René, Jørgensen, T., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Sørensen, Thorkild I.A. & Kilpeläinen, Tuomas O., 2019, In: European Journal of Human Genetics. 27, Suppl. 2, p. 1764 1 p.

Research output: Contribution to journal › Conference abstract in journal › Research

Extracellular Vesicle Encapsulated MicroRNAs in Patients with Type 2 Diabetes Are Affected by Metformin Treatment

Ghai, V., Kim, T., Etheridge, A., Nielsen, T., Hansen, Torben, Pedersen, Oluf Borbye, Galas, D. & Wang, K., 2019, In: Journal of Clinical Medicine. 8, 17 p., 617.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic Determinants of Weight Loss After Bariatric Surgery

Aasbrenn, M., Schnurr, T. M., Have, C. T., Svendstrup, M., Hansen, D. L., Worm, Dorte, Balslev-Harder, M., Hollensted, M., Grarup, Niels, Burgdorf, K. S., drb459, drb459, Pedersen, Oluf Borbye, Sørensen, Thorkild I.A., Fenger, M., Madsbad, Sten & Hansen, Torben, 2019, In: Obesity Surgery. 29, 8, p. 2554-2561 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic determinants of blood pressure traits are associated with carotid arterial thickening and plaque formation in patients with type 2 diabetes

pjx571, pjx571, Appel, V. E., Schnurr, T. M., Lundby-Christensen, L., Skaaby, T., Linneberg, Allan René, Drivsholm, Thomas, Witte, D. R., Jørgensen, M. E., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben & drb459, drb459, 2019, In: Diabetes and Vascular Disease Research. 16, 1, p. 13-21 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic predisposition to higher body fat yet lower cardiometabolic risk in children and adolescents

Viitasalo, A., Schnurr, T. M., Pitkänen, N., Hollensted, M., Nielsen, T. R. H., Pahkala, K., Lintu, N., Lind, M. V., Atalay, M., Frithioff-Bøjsøe, C., Fonvig, C. E., Grarup, N., Kähönen, M., Larnkjær, A., Pedersen, O. B., Holm, J-C., Michaelsen, K. F., Lakka, T. A., Lehtimäki, T., Raitakari, O. & 2 others, Hansen, Torben & Kilpeläinen, Tuomas O., 2019, In: International Journal of Obesity. 43, p. 2007-2016 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration

Wilman, H. R., Parisinos, C. A., Atabaki-Pasdar, N., Kelly, M., Thomas, E. L., Neubauer, S., Jennison, C., Ehrhardt, B., Baum, P., Schoelsch, C., Freijer, J., Grempler, R., Graefe-Mody, U., Hennige, A., Dings, C., Lehr, T., Scherer, N., Sihinecich, I., Pattou, F., Raverdi, V. & 31 others, Caiazzo, R., Torres, F., Verkindt, H., Mari, A., Tura, A., Giorgino, T., Bizzotto, Froguel, P., Brorsson, C., Brunak, Søren, De Masi, F., Pedersen, H., Banasik, Karina, Thomas, Cecilia Engel, Lundgaard, Agnete Troen, Nielsen, A., Mazzoni, G., Karaderi, Tugce, Rasmussen, Simon, Johansen, Joachim, Allesøe, R., Arumugam, Mani, Allin, K., Hansen, Torben, Hansen, T., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Dutta, A., Vogt, J., drb459, drb459 & IMI-DIRECT consortium, I. C., 2019, In: Journal of Hepatology. 71, 3, p. 594-602 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium

Dashti, H. S., Hansen, Torben, Astrup, A., Pedersen, Oluf Borbye, Sørensen, Thorkild I.A. & Cohorts for Heart and Aging Research in Genetic Epidemiology Consortium, C. F. H. A. A. R. I. G. E. C., 2019, In: Molecular Psychiatry. 24, p. 1920–1932

Research output: Contribution to journal › Journal article › Research › peer-review

Glucose metabolism in children and adolescents: Population-based reference values and comparisons to children and adolescents enrolled in obesity treatment

Frithioff-Bøjsøe, C., Lund, Morten Asp Vonsild, Kloppenborg, J. T., Nielsen, T. T. H., Fonvig, Cilius Esmann, Lausten-Thomsen, U., Hedley, P. L., Hansen, T., Pedersen, Oluf Borbye, Christiansen, M., Baker, J. L., Hansen, Torben & Holm, Jens-Christian, 2019, In: Pediatric Diabetes. 20, 5, p. 538-548

Research output: Contribution to journal › Journal article › Research › peer-review

Greater glucagon-like peptide-1 responses to oral glucose are associated with lower central and peripheral blood pressures

Lundgren, J. R., Faerch, K., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Holst, Jens Juul, Vistisen, D., Jorgensen, M. E., Torekov, Signe Sørensen & Johansen, N. B., 2019, In: Cardiovascular Diabetology. 18, 1, 9 p., 130.

Research output: Contribution to journal › Journal article › Research › peer-review

Gut microbiota composition in patients with newly diagnosed bipolar disorder and their unaffected first-degree relatives

Coello, K., Hansen, T. H., Sørensen, N., Munkholm, K., Kessing, Lars Vedel, Pedersen, Oluf Borbye & Vinberg, Maj, 2019, In: Brain, Behavior, and Immunity. 75, p. 112-118

Research output: Contribution to journal › Journal article › Research › peer-review

Habitual activity associates with lower fasting and greater glucose-induced GLP-1 response in men

Janus, C., Vistisen, D., Amadid, H., Witte, D. R., Lauritzen, T., Brage, S., Bjerregaard, A., Hansen, Torben, Holst, Jens Juul, Jørgensen, M. E., Pedersen, Oluf Borbye, Færch, K. & Torekov, Signe Sørensen, 2019, In: Endocrine Connections. 8, 12, p. 1607–1617 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes

Miguel-Escalada, I., Bonàs-Guarch, S., Cebola, I., Ponsa-Cobas, J., Mendieta-Esteban, J., Atla, G., Javierre, B. M., Rolando, D. M. Y., Farabella, I., Morgan, C. C., García-Hurtado, J., Beucher, A., Morán, I., Pasquali, L., Ramos-Rodríguez, M., Appel, E. V. R., Linneberg, A., Gjesing, A. P., Witte, D. R., Pedersen, O. & 16 others, Grarup, Niels, Ravassard, P., Torrents, D., Mercader, J. M., Piemonti, L., Berney, T., de Koning, E. J. P., Kerr-Conte, J., Pattou, F., Fedko, I. O., Groop, L., Prokopenko, I., Hansen, Torben, Marti-Renom, M. A., Fraser, P. & Ferrer, J., 2019, In: Nature Genetics. 51, 7, p. 1137-1148

Research output: Contribution to journal › Journal article › Research › peer-review

Increased frequency of rare missense PPP1R3B variants among Danish patients with type 2 diabetes

Niazi, R. K., Sun, J., Have, C. T., Hollensted, M., Linneberg, Allan René, Pedersen, Oluf Borbye, Nielsen, J. S., Rungby, Jørgen, Grarup, Niels, Hansen, Torben & Gjesing, A. P., 2019, In: PLoS ONE. 14, 1, p. 1-12 e0210114.

Research output: Contribution to journal › Journal article › Research › peer-review

Iron deficiency among blood donors: experience from the Danish Blood Donor Study and from the Copenhagen ferritin monitoring scheme

Rigas, A. S., Pedersen, Oluf Borbye, Magnussen, K., Erikstrup, C. & Ullum, H., 2019, In: Transfusion Medicine. 29, S1, p. 23-27

Research output: Contribution to journal › Review › Research › peer-review

Linking glycemic dysregulation in diabetes to symptoms, comorbidities, and genetics through EHR data mining

Kirk, I. K., Simon, C., Banasik, K., Holm, P. C., Haue, A. D., Jensen, P. B., Jensen, L. J., Rodriguez, C. L., Pedersen, M. K., Eriksson, R., Andersen, H. U., Almdal, T., Bork-Jensen, J., Grarup, N., Borch-Johnsen, K., Pedersen, O., Pociot, F., Hansen, T., Bergholdt, R., Rossing, P. & 1 others, Brunak, Søren, 2019, In: eLife. 8, 19 p., e44941.

Research output: Contribution to journal › Journal article › Research › peer-review

MR-proANP Associated with Body Mass Index in Patients with Anorexia Nervosa

Goetze, J. P., Gustafsson, Finn, Pedersen, Oluf Borbye & Støving, R. K., 2019, In: The journal of applied laboratory medicine. 4, 1, p. 132-134

Research output: Contribution to journal › Letter › Research › peer-review

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Stokholm, Jakob, Michaelsen, Kim F., Freathy, R. M. & EGG Consortium, E. C., 2019, In: Nature Genetics. 51, 5, p. 804-814

Research output: Contribution to journal › Journal article › Research › peer-review

Metformin-induced changes of the gut microbiota in healthy young men: results of a non-blinded, one-armed intervention study

Bryrup, T., Thomsen, C. W., Kern, T., Allin, K. H., Brandslund, I., Jørgensen, Niklas Rye, drb459, drb459, Hansen, Torben, Hansen, T. H., Pedersen, Oluf Borbye & Nielsen, T., 2019, In: Diabetologia. 62, 6, p. 1024-1035

Research output: Contribution to journal › Journal article › Research › peer-review

Obesity and unfavourable lifestyle increase type 2 diabetes-risk independent of genetic predisposition

Jakupovic, Hermina, Schnurr, T. M., Carrasquilla, Germán D., Grarup, Niels, Sørensen, Thorkild I.A., Tjønneland, Anne, Overvad, K., Pedersen, Oluf Borbye, Hansen, Torben & Kilpeläinen, Tuomas O., 2019, In: Diabetologia. 62, Suppl. 1, p. S188 1 p.

Research output: Contribution to journal › Conference abstract in journal › Research

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

Schmidt, A. F., Holmes, M. V., Preiss, D., Swerdlow, D. I., Denaxas, S., Fatemifar, G., Faraway, R., Finan, C., Valentine, D., Fairhurst-Hunter, Z., Hartwig, F. P., Horta, B. L., Hypponen, E., Power, C., Moldovan, M., Van Iperen, E., Hovingh, K., Demuth, I., Norman, K., Steinhagen-Thiessen, E. & 145 others, Demuth, J., Bertram, L., Lill, C. M., Coassin, S., Willeit, J., Kiechl, S., Willeit, K., Mason, D., Wright, J., Morris, R., Wanamethee, G., Whincup, P., Ben-Shlomo, Y., McLachlan, S., Price, J. F., Kivimaki, M., Welch, C., Sanchez-Galvez, A., Marques-Vidal, P., Nicolaides, A., Panayiotou, A. G., Onland-Moret, N. C., Van Der Schouw, Y. T., Matullo, G., Fiorito, G., Guarrera, S., Sacerdote, C., Wareham, N. J., Langenberg, C., Scott, R. A., Luan, J., Bobak, M., Malyutina, S., Pajak, A., Kubinova, R., Tamosiunas, A., Pikhart, H., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Linneberg, Allan René, Jess, T., Cooper, J., Humphries, S. E., Brilliant, M., Kitchner, T., Hakonarson, H., Carrell, D. S., McCarty, C. A., Lester, K. H., Larson, E. B., Crosslin, D. R., De Andrade, M., Roden, D. M., Denny, J. C., Carty, C., Hancock, S., Attia, J., Holliday, E., Scott, R., Schofield, P., O'Donnell, M., Yusuf, S., Chong, M., Pare, G., Van Der Harst, P., Said, M. A., Eppinga, R. N., Verweij, N., Snieder, H., Christen, T., Mook-Kanamori, D. O., Gustafsson, S., Lind, L., Ingelsson, E., Pazoki, R., Franco, O., Hofman, A., Uitterlinden, A., Dehghan, A., Teumer, A., Baumeister, S., Dörr, M., Lerch, M. M., Völker, U., Völzke, H., Ward, J., Pell, J. P., Meade, T., Christophersen, I. E., Maitland-Van Der Zee, A. H., Baranova, E. V., Young, R., Ford, I., Campbell, A., Padmanabhan, S., Bots, M. L., Grobbee, D. E., Froguel, P., Thuillier, D., Roussel, R., Bonnefond, A., Cariou, B., Smart, M., Bao, Y., Kumari, M., Mahajan, A., Hopewell, J. C., Seshadri, S., Dale, C., Costa, R. P. E., Ridker, P. M., Chasman, D. I., Reiner, A. P., Ritchie, M. D., Lange, L. A., Cornish, A. J., Dobbins, S. E., Hemminki, K., Kinnersley, B., Sanson, M., Labreche, K., Simon, M., Bondy, M., Law, P., Speedy, H., Allan, J., Li, N., Went, M., Weinhold, N., Morgan, G., Sonneveld, P., Nilsson, B., Goldschmidt, H., Sud, A., Engert, A., Hansson, M., Hemingway, H., Asselbergs, F. W., Patel, R. S., Keating, B. J., Sattar, N., Houlston, R., Casas, J. P. & Hingorani, A. D., 2019, In: BMC Cardiovascular Disorders. 19, 1, 10 p., 240.

Research output: Contribution to journal › Journal article › Research › peer-review

Polygenic predisposition to breast cancer and the risk of coronary artery disease

D'Souza, M., Schou, Morten, Skals, R., Weeke, P. E., Lee, C., Smedegaard, L., Madelaire, C., Gerds, Thomas Alexander, Poulsen, Henrik Enghusen, Hansen, Torben, Grarup, Niels, Pedersen, Oluf Borbye, Stender, Steen, Engstrøm, Thomas, Fosbøl, E., Nielsen, D., Gislason, Gunnar Hilmar, Køber, Lars Valeur, Torp-Pedersen, C. & Andersson, C., 2019, In: International Journal of Cardiology. 291, p. 145-151 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

Justice, A. E., Karaderi, T., Highland, H. M., Young, K. L., Graff, M., Lu, Y., Turcot, V., Auer, P. L., Fine, R. S., Guo, X., Schurmann, C., Lempradl, A., Marouli, E., Mahajan, A., Winkler, T. W., Locke, A. E., Medina-Gomez, C., Esko, T., Vedantam, S., Giri, A. & 31 others, Lo, K. S., Alfred, T., Mudgal, P., Ng, M. C. Y., Heard-Costa, N. L., Feitosa, M. F., Manning, A. K., Willems, S. M., Sivapalaratnam, S., Abecasis, G., Alam, D. S., Allison, M., Amouyel, P., Arzumanyan, Z., Balkau, B., Bork-Jensen, J., Grarup, Niels, Hansen, Torben, Jørgensen, T., Justesen, Johanne Marie, Karpe, F., Kovacs, P., Li, J., Lind, L., Linneberg, Allan René, Pedersen, Oluf Borbye, Pers, Tune H, drb459, drb459, Zhao, J. H., Loos, R. J. F. & CHD Exome+ Consortium, C. E. C., 2019, In: Nature Genetics. 51, 3, p. 452-469 18 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis

Merino, J., Guasch-Ferré, M., Ellervik, C., Dashti, H. S., Sharp, S. J., Wu, P., Overvad, K., Sarnowski, C., Kuokkanen, M., Lemaitre, R. N., Justice, A. E., Ericson, U., Braun, K. V. E., Mahendran, Y., Frazier-Wood, A. C., Sun, D., Chu, A. Y., Tanaka, T., Luan, J., Hong, J. & 48 others, Tjønneland, Anne, Ding, M., Lundqvist, A., Mukamal, K., Rohde, R., Schulz, C., Franco, O. H., Grarup, Niels, Chen, Y. I., Bazzano, L., Franks, P. W., Buring, J. E., Langenberg, C., Liu, C., Hansen, Torben, Jensen, Majken Karoline, Sääksjärvi, K., Psaty, B. M., Young, K. L., Hindy, G., Sandholt, C. H., Ridker, P. M., Ordovas, J. M., Meigs, J. B., Pedersen, Oluf Borbye, Kraft, P., Perola, M., North, K. E., Orho-Melander, M., Voortman, T., Toft, Ulla Marie Nørgaard, Rotter, J. I., Qi, L., Forouhi, N. G., Mozaffarian, D., Sørensen, Thorkild I.A., Stampfer, M. J., Männistö, S., Selvin, E., Imamura, F., Salomaa, V., Hu, F. B., Wareham, N. J., Dupuis, J., Smith, C. E., Kilpeläinen, Tuomas O., Chasman, D. I. & Florez, J. C., 2019, In: BMJ (Clinical research ed.). 366, p. l4292

Research output: Contribution to journal › Journal article › Research › peer-review

Reference values for fasting serum concentrations of thyroid-stimulating hormone and thyroid hormones in healthy Danish/North-European white children and adolescents

Gunapalasingham, G., Frithioff-Bojsoe, C., Lund, Morten Asp Vonsild, Hedley, P. L., Fonvig, Cilius Esmann, Dahl, M., Pedersen, Oluf Borbye, Christiansen, M., Hansen, Torben, Lausten-Thomsen, U. & Holm, Jens-Christian, 2019, In: Scandinavian Journal of Clinical & Laboratory Investigation. 79, 1-2, p. 129-135

Research output: Contribution to journal › Journal article › Research › peer-review

Reference values for leptin/adiponectin ratio in healthy children and adolescents

Lausten-Thomsen, U., Lund, Morten Asp Vonsild, Frithioff-Bojsoe, C., Hedley, P. L., Pedersen, Oluf Borbye, Hansen, Torben, Christiansen, M. & Holm, Jens-Christian, 2019, In: Clinica Chimica Acta. 493, p. 123-128

Research output: Contribution to journal › Journal article › Research › peer-review

Remitted affective disorders and high familial risk of affective disorders associate with aberrant intestinal microbiota

Vinberg, Maj, Ottesen, N. M., Meluken, I., Sørensen, N., Pedersen, Oluf Borbye, Kessing, Lars Vedel & Miskowiak, Kamilla, 2019, In: Acta Psychiatrica Scandinavica. 139, 2, p. 174-184 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Screening of 31 genes involved in monogenic forms of obesity in 23 Pakistani probands with early-onset childhood obesity: a case report

Niazi, R. K., Gjesing, A. P., Hollensted, M., Have, C. T., Borisevich, D., Grarup, Niels, Pedersen, Oluf Borbye, Ullah, A., Shahid, G., Shafqat, I., Gul, A. & Hansen, Torben, 2019, In: B M C Medical Genetics. 20, 8 p., 152.

Research output: Contribution to journal › Journal article › Research › peer-review

Sequencing reveals protective and pathogenic effects on development of diabetes of rare GLIS3 variants

Sun, J., Have, C. T., Hollensted, M., Grarup, Niels, Linneberg, Allan René, Pedersen, Oluf Borbye, Nielsen, J. S., Rungby, Jørgen, Christensen, C., Brandslund, I., Kristiansen, Karsten, Jun, W., Hansen, Torben & Gjesing, A. P., 2019, In: PLoS ONE. 14, 8, 10 p., e0220805.

Research output: Contribution to journal › Journal article › Research › peer-review

The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects

Middeldorp, C. M., Mahajan, A., Horikoshi, M., Robertson, N. R., Beaumont, R. N., Bradfield, J. P., Bustamante, M., Cousminer, D. L., Day, F. R., De Silva, N. M., Guxens, M., Mook-Kanamori, D. O., St Pourcain, B., Warrington, N. M., Adair, L. S., Ahlqvist, E., Ahluwalia, T. S., Almgren, P., Ang, W., Atalay, M. & 463 others, Auvinen, J., Bartels, M., Beckmann, J. S., Bilbao, J. R., Bond, T., Borja, J. B., Cavadino, A., Charoen, P., Chen, Z., Coin, L., Cooper, C., Curtin, J. A., Custovic, A., Das, S., Davies, G. E., Dedoussis, G. V., Duijts, L., Eastwood, P. R., Eliasen, A. U., Elliott, P., Eriksson, J. G., Estivill, X., Fadista, J., Fedko, I. O., Frayling, T. M., Gaillard, R., Gauderman, W. J., Geller, F., Gilliland, F., Gilsanz, V., Granell, R., Grarup, Niels, Groop, L., Hadley, D., Hakonarson, H., Hansen, Torben, Hartman, C. A., Hattersley, A. T., Hayes, M. G., Hebebrand, J., Heinrich, J., Helgeland, O., Henders, A. K., Henderson, J., Henriksen, T. B., Hirschhorn, J. N., Hivert, M., Hocher, B., Holloway, J. W., Holt, P., Hottenga, J., Hypponen, E., Iniguez, C., Johansson, S., Jugessur, A., Kahonen, M., Kalkwarf, H. J., Kaprio, J., Karhunen, V., Kemp, J. P., Kerkhof, M., Koppelman, G. H., Korner, A., Kotecha, S., Kreiner-Moller, E., Kulohoma, B., Kumar, A., Kutalik, Z., Lahti, J., Lappe, J. M., Larsson, H., Lehtimaki, T., Lewin, A. M., Li, J., Lichtenstein, P., Lindgren, C. M., Lindi, V., Linneberg, Allan René, Liu, X., Liu, J., Lowe, W. L. ,. J., Lundstrom, S., Lyytikainen, L., Ma, R. C. W., Mace, A., Magi, R., Magnus, P., Mamun, A. A., Mannikko, M., Martin, N. G., Mbarek, H., McCarthy, N. S., Medland, S. E., Melbye, M., Melen, E., Mohlke, K. L., Monnereau, C., Morgen, C. S., Morris, A. P., Murray, J. C., Myhre, R., Najman, J. M., Nivard, M. G., Nohr, E. A., Nolte, I. M., Ntalla, I., O'Reilly, P., Oberfield, S. E., Oken, E., Oldehinkel, A. J., Pahkala, K., Palviainen, T., Panoutsopoulou, K., Pedersen, Oluf Borbye, Pennell, C. E., Pershagen, G., Pitkanen, N., Plomin, R., Power, C., Prasad, R. B., Prokopenko, I., Pulkkinen, L., Raikkonen, K., Raitakari, O. T., Reynolds, R. M., Richmond, R. C., Rivadeneira, F., Rodriguez, A., Rose, R. J., Salem, R., Santa-Marina, L., Saw, S., Schnurr, T. M., Scott, J. G., Selzam, S., Shepherd, J. A., Simpson, A., Skotte, L., Sleiman, P. M. A., Snieder, H., Sørensen, Thorkild I.A., Standl, M., Steegers, E. A. P., Strachan, D. P., Straker, L., Strandberg, T., Taylor, M., Teo, Y., Thiering, E., Torrent, M., Tyrrell, J., Uitterlinden, A. G., van Beijsterveldt, T., van der Most, P. J., van Duijn, C. M., Viikari, J., Vilor-Tejedor, N., Vogelezang, S., Vonk, J. M., Vrijkotte, T. G. M., Vuoksimaa, E., Wang, C. A., Watkins, W. J., Wichmann, H., Willemsen, G., Williams, G. M., Wilson, J. F., Wray, N. R., Xu, S., Xu, C., Yaghootkar, H., Yi, L., Zafarmand, M. H., Zeggini, E., Zemel, B. S., Hinney, A., Lakka, T. A., Whitehouse, A. J. O., Sunyer, J., Widen, E. E., Feenstra, B., Sebert, S., Jacobsson, B., Njolstad, P. R., Stoltenberg, C., Smith, G. D., Lawlor, D. A., Paternoster, L., Timpson, N. J., Ong, K. K., Bisgaard, H., Bønnelykke, Klaus, Jaddoe, V. W. V., Tiemeier, H., Jarvelin, M., Evans, D. M., Perry, J. R. B., Grant, S. F. A., Boomsma, D. I., Freathy, R. M., McCarthy, M. I., Adair, L. S., Ahlqvist, E., Ahluwalia, Tarun Veer Singh, Almgren, P., Ang, W., Atalay, M., Beaumont, R. N., Beckmann, J. S., Bisgaard, H., Bond, T., Bønnelykke, Klaus, Boomsma, D. I., Borja, J. B., Bradfield, J. P., Bustamante, M., Cavadino, A., Charoen, P., Coin, L., Cooper, C., Cousminer, D. L., Curtin, J. A., Custovic, A., Das, S., Day, F. R., De Silva, N. M., Dedoussis, G. V., Elliott, P., Eriksson, J. G., Evans, D. M., Fadista, J., Feenstra, B., Felix, J. F., Frayling, T. M., Freathy, R. M., Gaillard, R., Geller, F., Gilsanz, V., Grant, S. F. A., Grarup, Niels, Groop, L., Guxens, M., Hadley, D., Hakonarson, H., Hansen, Torben, Hattersley, A. T., Hayes, M. G., Hebebrand, J., Heinrich, J., Helgeland, O., Henriksen, T. B., Hinney, A., Hirschhorn, J. N., Hivert, M., Hocher, B., Holloway, J. W., Horikoshi, M., Hottenga, J., Hypponen, E., Jacobsson, B., Jaddoe, V. W. V., Jarvelin, M., Johansson, S., Kalkwarf, H. J., Kerkhof, M., Korner, A., Kotecha, S., Kreiner-Moller, E., Kulohoma, B., Kutalik, Z., Lakka, T. A., Lappe, J. M., Lawlor, D. A., Lehtimaki, T., Lewin, A. M., Lindgren, C. M., Lindi, V., Linneberg, Allan René, Liu, X., Liu, J., Lowe, W. L. ,. J., Ma, R. C. W., Mace, A., Magi, R., Magnus, P., Mahajan, A., McCarthy, N. S., McCarthy, M. I., Melbye, M., Mohlke, K. L., Monnereau, C., Mook-Kanamori, D. O., Morgen, C. S., Morris, A. P., Murray, J. C., Myhre, R., Njolstad, P. R., Nohr, E. A., Ntalla, I., O'Reilly, P., Oberfield, S. E., Oken, E., Ong, K. K., Panoutsopoulou, K., Pedersen, Oluf Borbye, Pennell, C. E., Perry, J. R. B., Pitkanen, N., St Pourcain, B., Power, C., Prasad, R. B., Prokopenko, I., Raitakari, O. T., Reynolds, R. M., Richmond, R. C., Rodriguez, A., Salem, R., Saw, S., Schnurr, T. M., Sebert, S., Shepherd, J. A., Simpson, A., Skotte, L., Sørensen, Thorkild I.A., Standl, M., Steegers, E. A. P., Strachan, D. P., Sunyer, J., Taylor, M., Teo, Y., Thiering, E., Timpson, N. J., Tyrrell, J., Uitterlinden, A. G., van Duijn, C. M., Vogelezang, S., Vrijkotte, T. G. M., Wang, C. A., Warrington, N. M., Watkins, W. J., Wichmann, H., Widen, E. E., Willemsen, G., Wilson, J. F., Yaghootkar, H., Zafarmand, M. H., Zeggini, E., Zemel, B. S., Ahluwalia, T. S., Auvinen, J., Bartels, M., Bilbao, J. R., Bisgaard, H., Bønnelykke, Klaus, Boomsma, D. I., Bradfield, J. P., Bustamante, M., Chen, Z., Curtin, J. A., Custovic, A., Smith, G. D., Davies, G. E., Duijts, L., Eastwood, P. R., Eliasen, A. U., Estivill, X., Evans, D. M., Fedko, I. O., Felix, J. F., Gauderman, W. J., Gilliland, F., Granell, R., Grant, S. F. A., Guxens, M., Hakonarson, H., Hartman, C. A., Heinrich, J., Henders, A. K., Henderson, J., Holt, P., Hottenga, J., Hypponen, E., Iniguez, C., Jacobsson, B., Jaddoe, V. W. V., Jarvelin, M., Jugessur, A., Kahonen, M., Kaprio, J., Karhunen, V., Kemp, J. P., Koppelman, G. H., Kumar, A., Lahti, J., Larsson, Henrik Bo Wiberg, Lawlor, D. A., Lehtimaki, T., Li, J., Lichtenstein, P., Lundstrom, S., Lyytikainen, L., Magnus, P., Mamun, A. A., Mannikko, M., Martin, N. G., Mbarek, H., Medland, S. E., Melen, E., Middeldorp, C. M., Najman, J. M., Nivard, M. G., Nolte, I. M., Oldehinkel, A. J., Pahkala, K., Palviainen, T., Paternoster, L., Pennell, C. E., Pershagen, G., Pitkanen, N., Plomin, R., St Pourcain, B., Power, C., Pulkkinen, L., Raikkonen, K., Raitakari, O. T., Richmond, R. C., Rivadeneira, F., Rose, R. J., Santa-Marina, L., Scott, J. G., Sebert, S., Selzam, S., Simpson, A., Sleiman, P. M. A., Snieder, H., Standl, M., Stoltenberg, C., Strachan, D. P., Straker, L., Strandberg, T., Sunyer, J., Thiering, E., Tiemeier, H., Timpson, N. J., Torrent, M., Uitterlinden, A. G., van Beijsterveldt, T., van der Most, P. J., van Duijn, C. M., Viikari, J., Vilor-Tejedor, N., Vonk, J. M., Vrijkotte, T. G. M., Vuoksimaa, E., Wang, C. A., Whitehouse, A. J. O., Willemsen, G., Williams, G. M., Wray, N. R., Xu, S., Xu, C., Yi, L. & Zafarmand, M. H., 2019, In: European Journal of Epidemiology. 34, 3, p. 279-300 22 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The antidepressant-like effect of probiotics and their faecal abundance may be modulated by the cohabiting gut microbiota in rats

Abildgaard, A., Kern, T., Pedersen, Oluf Borbye, Hansen, Torben, Wegener, G. & Lund, S., 2019, In: European Neuropsychopharmacology. 29, 1, p. 98-110

Research output: Contribution to journal › Journal article › Research › peer-review

Trimethylamine-N-Oxide and Renal Complications, Cardiovascular Disease, and Mortality in Individuals with Type 2 Diabetes and Microalbuminuria

Winther, S. A., Øllgaard, J. C., Hansen, T., von Scholten, B. J., Gaede, P., Parving, H., Pedersen, Oluf Borbye & Rossing, Peter, 2019, In: Journal of the American Society of Nephrology. 30, Kidney Week Edition, p. 904 1 p., SA-PO551.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Utility of Plasma Concentration of Trimethylamine N-Oxide in Predicting Cardiovascular and Renal Complications in Individuals With Type 1 Diabetes

Winther, S. A., Øllgaard, J. C., Tofte, N., Tarnow, L., Wang, Z., Ahluwalia, T. S., Jorsal, A., Theilade, S., Parving, H., Hansen, T. W., Hazen, S. L., Pedersen, Oluf Borbye & Rossing, Peter, 2019, In: Diabetes Care. 42, 8, p. 1512-1520

Research output: Contribution to journal › Journal article › Research › peer-review

Recovery of gut microbiota of healthy adults following antibiotic exposure

Palleja, A., Mikkelsen, K. H., Forslund, S. K., Kashani, A., Allin, K. H., Nielsen, T., Hansen, T. H., Liang, S., Feng, Q., Zhang, C., Pyl, P. T., Coelho, L. P., Yang, H., Wang, J., Typas, A., Nielsen, M. F., Nielsen, H. B., Bork, P., Wang, J., Vilsbøll, T. & 4 others, Hansen, Torben, Knop, Filip Krag, Arumugam, Mani & Pedersen, Oluf Borbye, Nov 2018, In: Nature Microbiology. 3, 11, p. 1255-1265 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Population-based studies of relationships between dietary acidity load, insulin resistance and incident diabetes in Danes 11 Medical and Health Sciences 1103 Clinical Sciences

Gæde, J., Nielsen, T., Madsen, M. L., Toft, Ulla Marie Nørgaard, Jørgensen, T., Overvad, K., Tjønneland, Anne, Hansen, Torben, Allin, K. H. & Pedersen, Oluf Borbye, 6 Oct 2018, In: Nutrition Journal. 17, 1, 91.

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population

Grarup, Niels, Moltke, Ida, Lepola, Mette Andersen, Bjerregaard, P., Larsen, C. V. L., Dahl-Petersen, I. K., Jørsboe, E., Tiwari, H. K., Hopkins, S. E., Wiener, H. W., Boyer, B. B., Linneberg, Allan René, Pedersen, Oluf Borbye, Jørgensen, M. E., Albrechtsen, Anders & Hansen, Torben, 1 Sep 2018, In: Diabetologia. 61, 9, p. 2005–2015

Research output: Contribution to journal › Journal article › Research › peer-review

An adult-based insulin resistance genetic risk score associates with insulin resistance, metabolic traits and altered fat distribution in Danish children and adolescents who are overweight or obese

Graae, A. S., Hollensted, M., Kloppenborg, J. T., Mahendran, Y., Schnurr, T. M., Appel, E. V. R., Rask, J., Nielsen, T. R. H., Johansen, M., Linneberg, Allan René, Jørgensen, M. E., Grarup, Niels, Kadarmideen, H. N., Holst, Birgitte, Pedersen, Oluf Borbye, Holm, Jens-Christian & Hansen, Torben, Aug 2018, In: Diabetologia. 61, 8, p. 1769-1779

Research output: Contribution to journal › Journal article › Research › peer-review

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

Prins, B. P., Mead, T. J., Brody, J. A., Sveinbjornsson, G., Ntalla, I., Bihlmeyer, N. A., van den Berg, M., Bork-Jensen, J., Cappellani, S., Van Duijvenboden, S., Klena, N. T., Gabriel, G. C., Liu, X., Gulec, C., Grarup, N., Haessler, J., Hall, L. M., Iorio, A., Isaacs, A., Li-Gao, R. & 31 others, Lin, H., Liu, C., Lyytikäinen, L., Marten, J., Mei, H., Müller-Nurasyid, M., Orini, M., Padmanabhan, S., Radmanesh, F., Ramirez, J., Robino, A., Schwartz, M., van Setten, J., Smith, A. V., Verweij, N., Warren, H. R., Weiss, S., Alonso, A., Arnar, D. O., Bots, M. L., de Boer, R. A., Dominiczak, A. F., Eijgelsheim, M., Ellinor, P. T., Guo, X., Felix, S. B., Linneberg, Allan René, Pedersen, Oluf Borbye, Hansen, Torben, Kanters, Jørgen K. & et al., E. A., 17 Jul 2018, In: Genome Biology. 19, 17 p., 87.

Research output: Contribution to journal › Journal article › Research › peer-review

Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum

Crusell, Mie Korslund Wiinblad, Hansen, T. H., Nielsen, T., Allin, K. H., Rühlemann, M. C., Damm, Peter, drb459, drb459, Rørbye, Christina, Jørgensen, N. R., Christiansen, O. B., Heinsen, F., Franke, A., Hansen, Torben, Lauenborg, J. & Pedersen, Oluf Borbye, 15 May 2018, In: Microbiome. 6, 19 p., 89.

Research output: Contribution to journal › Journal article › Research › peer-review

Impaired fasting glucose and the metabolic profile in Danish children and adolescents with normal weight, overweight, or obesity

Kloppenborg, J. T., Fonvig, Cilius Esmann, Nielsen, T. R. H., Mollerup, P. M., Bøjsøe, C., Pedersen, Oluf Borbye, Johannesen, Jesper, Hansen, Torben & Holm, Jens-Christian, May 2018, In: Pediatric Diabetes. 19, 3, p. 356-365

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Aberrant intestinal microbiota in individuals with prediabetes

Allin, K. H., Tremaroli, V., Caesar, R., Jensen, Benjamin Anderschou Holbech, Damgaard, Mads Vargas, Bahl, M. I., Licht, T. R., Hansen, T. H., Nielsen, T., Dantoft, T. M., Linneberg, Allan René, Jørgensen, T., drb459, drb459, Kristiansen, Karsten, Franks, P. W., IMI-DIRECT consortium, I. C., Hansen, Torben, Bäckhed, G. F. & Pedersen, Oluf Borbye, Apr 2018, In: Diabetologia. 61, 4, p. 810-820 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N. W., Guo, X., Lu, Y., Li, M., Jensen, R. A., Hu, Y., Huo, S., Lohman, K. K., Zhang, W., Cook, J. P., Prins, B. P. & 32 others, Flannick, J., Grarup, Niels, Trubetskoy, V. V., Kravic, J., Kim, Y. J., Rybin, D. V., Yaghootkar, H., Müller-Nurasyid, M., Meidtner, K., Li-Gao, R., Varga, T. V., Marten, J., Li, J., Afzal, Shoaib, Bork-Jensen, J., Tybjærg-Hansen, Anne, Jørgensen, M. E., Jørgensen, T., Kovacs, P., Linneberg, Allan René, Liu, J., Nielsen, S. F., Rode, L., Witte, D. R., Hansen, Torben, Karpe, F., Lind, L., Loos, R. J. F., Nordestgaard, Børge, Pedersen, Oluf Borbye, ExomeBP Consortium, E. C. & V Varga, Tibor, Apr 2018, In: Nature Genetics. 50, 4, p. 559-571 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The association of IgA deficiency on infection rate, self-perceived health, and levels of C-reactive protein in healthy blood donors

Hauge, S. C., Jensen, C. K., Nielsen, L. K., Pedersen, Oluf Borbye, Sørensen, E., Thørner, L. W., Hjalgrim, H., Erikstrup, C., Nielsen, K. R., Kaspersen, K. A., Didriksen, Maria, Dziegiel, Morten Hanefeld & Ullum, H., 1 Mar 2018, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 126, 3, p. 248-256 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Obesity is associated with vitamin D deficiency in Danish children and adolescents

Plesner, J. L., Dahl, M., Fonvig, Cilius Esmann, Nielsen, T. R. H., Kloppenborg, J. T., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 26 Jan 2018, In: Journal of Pediatric Endocrinology and Metabolism. 31, 1, p. 53-61 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes

Bonàs-Guarch, S., Guindo-Martínez, M., Miguel-Escalada, I., Grarup, N., Sebastian, D., Rodriguez-Fos, E., Sánchez, F., Planas-Fèlix, M., Cortes-Sánchez, P., González, S., Timshel, P., Pers, T. H., Morgan, C. C., Moran, I., Atla, G., González, J. R., Puiggros, M., Martí, J., Andersson, E. A., Díaz, C. & 23 others, Badia, R. M., Udler, M., Leong, A., Kaur, V., Flannick, J., Jørgensen, T., Linneberg, Allan René, Jørgensen, M. E., Witte, D. R., Christensen, C., Brandslund, I., Appel, E. V., Scott, R. A., Luan, J., Langenberg, C., Wareham, N. J., Pedersen, Oluf Borbye, Zorzano, A., Florez, J. C., Hansen, Torben, Ferrer, J., Mercader, J. M. & Torrents, D., 22 Jan 2018, In: Nature Communications. 9, 14 p., 321.

Research output: Contribution to journal › Journal article › Research › peer-review

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Turcot, V., Lu, Y., Highland, H. M., Bang, L. E., Benn, M., Kamstrup, P. R., Bork-Jensen, J., Frikke-Schmidt, R., Gjesing, A. P., Grarup, N., Hansen, T., Have, C. T., Jørgensen, T., Nielsen, S. F., Linneberg, A. R., Pedersen, O., Pers, T. H., Vestergaard, H., Nordestgaard, B., Tybjærg-Hansen, A. & 15 others, Varbo, A., CHD Exome+ Consortium, C. E. C., EPIC-CVD Consortium, E. C., ExomeBP Consortium, E. C., Global Lipids Genetics Consortium, G. L. G. C., GoT2D Genes Consortium, G. G. C., EPIC-InterAct Consortium, E. C., INTERVAL Study, I. S., ReproGen Consortium, R. C., T2D-Genes Consortium, T. C., The MAGIC Investigators, T. M. I., Understanding Society Scientific Group, U. S. S. G., Lindgren, C. M., Hirschhorn, J. N. & Loos, R. J. F., 1 Jan 2018, In: Nature Genetics. 50, p. 26-41 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

In vivo and ex vivo inflammatory markers of common metabolic phenotypes in humans

Mærkedahl, R. B., Frøkiær, Hanne, Stenbæk, M. G., Nielsen, C. B., Lind, M. V., Lundtoft, C., Bohr, M. B., Ibrügger, S., Metzdorff, S. B., drb459, drb459, Pedersen, Oluf Borbye & Lauritzen, Lotte, 2018, In: Metabolic Syndrome and Related Disorders. 16, 1, p. 29-39 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A computational framework to integrate high-throughput "-omics" datasets for the identification of potential mechanistic links

Pedersen, H. K., Forslund, S. K., Gudmundsdottir, V., Petersen, A. Ø., Hildebrand, F., Hyötyläinen, T., Nielsen, T., Hansen, Torben, Bork, P., Ehrlich, S. D., Brunak, Søren, Oresic, M., Pedersen, Oluf Borbye & Nielsen, H. B., 2018, In: Nature Protocols. 13, 12, p. 2781-2800 20 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A genome-wide association study of diabetic kidney disease in subjects with type 2 diabetes

Van Zuydam, N. R., Ahlqvist, E., Sandholm, N., Deshmukh, H., William Rayner, N., Abdalla, M., Ladenvall, C., Ziemek, D., Fauman, E., Robertson, N. R., McKeigue, P. M., Valo, E., Forsblom, C., Harjutsalo, V., Perna, A., Rurali, E., Loredana Marcovecchio, M., Igo, R. P., Lajer, M., Ahluwalia, T. S. & 7 others, Linneberg, Allan René, Witte, D. R., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Rossing, Peter & SUrrogate markers for Micro- and Macrovascular hard endpoints for Innovative diabetes Tools (SUMMIT) Consortium, S. M. F. M. A. M. H. E. F. I. D. T. (. C., 2018, In: Diabetes. 67, 7, p. 1414-1427 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults

Hansen, L. B. S., Roager, H. M., Søndertoft, N. B., Gøbel, R. J., Kristensen, M. B., Vallès-Colomer, M., Vieira-Silva, S., Ibrügger, S., Lind, M. V., Mærkedahl, R. B., Bahl, M. I., Madsen, M. L., Havelund, J., Falony, G., Tetens, I., Nielsen, T., Allin, K. H., Frandsen, H. L., Hartmann, B., Holst, J. J. & 32 others, Sparholt, M. H., Holck, J., Blennow, Andreas, Moll, J. M., Meyer, A. S., Hoppe, C., Poulsen, J. H., Carvalho, V., Sagnelli, D., Dalgaard, M. D., Christensen, A. F., Lydolph, M., Ross, A. B., Villas-Bôas, S. G., Brix, S., Sicheritz-Pontén, T., Buschard, K., Linneberg, Allan René, Rumessen, J. J., Ekstrøm, Claus Thorn, Ritz, C., Kristiansen, Karsten, Nielsen, H. B., drb459, drb459, Færgeman, N. J., Raes, J., Frøkiær, Hanne, Hansen, Torben, Lauritzen, Lotte, Gupta, R., Licht, T. R. & Pedersen, Oluf Borbye, 2018, In: Nature Communications. 9, 13 p., 4630.

Research output: Contribution to journal › Journal article › Research › peer-review

Accurate genotyping across variant classes and lengths using variant graphs

Sibbesen, Jonas Andreas, Maretty, L., Krogh, Anders, Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Have, C. T., Bork-Jensen, J., Guo, X., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Wang, J. & Brunak, Søren, 2018, In: Nature Genetics. 50, p. 1054-1059 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Application of urinary proteomics as possible risk predictor of renal and cardiovascular complications in patients with type 2-diabetes and microalbuminuria

Oellgaard, J., Gæde, P., Persson, F., Rossing, Peter, Parving, H. & Pedersen, Oluf Borbye, 2018, In: Journal of Diabetes and its Complications. 32, 12, p. 1133-1140

Research output: Contribution to journal › Journal article › Research › peer-review

Associations of genetic determinants of serum vitamin B12 and folate concentrations with hay fever and asthma: a Mendelian randomization meta-analysis

Skaaby, T., Taylor, A. E., Jacobsen, R. K., Møllehave, L. T., Friedrich, N., Thuesen, B. H., Shabanzadeh, D. M., Paternoster, L., Völker, U., Nauck, M., Völzke, H., Munafò, M., Hansen, Torben, Pedersen, Oluf Borbye, Jørgensen, T., Grarup, Niels & Linneberg, Allan René, 2018, In: European Journal of Clinical Nutrition. 72, 2, p. 264–271 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Benchmarking the HLA typing performance of Polysolver and Optitype in 50 Danish parental trios

Matey-Hernandez, M. L., Danish Pan Genome Consortium, D. P. G. C., Brunak, Søren, Izarzugaza, J. M. G., Sørensen, L. M., Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Belling, K. G., Have, C. T., Bork-Jensen, J., Sun, J., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Wang, J., Eiberg, Hans Rudolf Lytchoff & Kristiansen, Karsten, 2018, In: BMC Bioinformatics. 19, p. 1-12 239.

Research output: Contribution to journal › Journal article › Research › peer-review

Bone turnover, calcium homeostasis, and vitamin D status in Danish vegans

Hansen, T. H., Madsen, M. T. B., Jørgensen, N. R., Cohen, A. S., Hansen, Torben, drb459, drb459, Pedersen, Oluf Borbye & Allin, K. H., 2018, In: European Journal of Clinical Nutrition. 72, p. 1046-1054 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Brugada Syndrome-Associated Genetic Loci Are Associated With J-Point Elevation and an Increased Risk of Cardiac Arrest

Andreasen, Laura Korsholm, Ghouse, J., Skov, M. W., Have, C. T., Ahlberg, G., Rasmussen, P. V., Linneberg, Allan René, Pedersen, Oluf Borbye, Platonov, P. G., Haunsø, Stig, Svendsen, Jesper Hastrup, Hansen, Torben, Kanters, Jørgen K. & Olesen, Morten Steen Salling, 2018, In: Frontiers in Physiology. 9, p. 1-9 894.

Research output: Contribution to journal › Journal article › Research › peer-review

Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis

Sustarsic, E. G., Ma, T., Lynes, M. D., Larsen, M., Karavaeva, I., Havelund, J. F., Nielsen, C. H., Jedrychowski, M. P., Moreno-Torres, M., Lundh, M., Plucinska, K., Jespersen, N. Z., Grevengoed, T. J., Kramar, B., Peics, J., Hansen, J. B., Shamsi, F., Forss, I., Neess, D., Keipert, S. & 24 others, Wang, J., Stohlmann, K., Brandslund, I., Christensen, C., Jørgensen, M. E., Linneberg, Allan René, Pedersen, Oluf Borbye, Kiebish, M. A., Qvortrup, Klaus, Han, X., Pedersen, Bente Klarlund, Jastroch, M., Mandrup, S., Kjær, Andreas, Gygi, S. P., Hansen, Torben, Gillum, M. P., Grarup, Niels, Emanuelli, Brice, Nielsen, S., Schéele, Camilla Charlotte Nielsen, Tseng, Y., Færgeman, N. J. & Gerhart-Hines, Zach, 2018, In: Cell Metabolism. 28, 1, p. 159-174.e11

Research output: Contribution to journal › Journal article › Research › peer-review

Childhood obesity treatment; Effects on BMI SDS, body composition, and fasting plasma lipid concentrations

Nielsen, T. R. H., Fonvig, Cilius Esmann, Dahl, M., Mollerup, P. M., Lausten-Thomsen, U., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 2018, In: P L o S One. 13, 2, p. 1-18 18 p., e0190576.

Research output: Contribution to journal › Journal article › Research › peer-review

Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

Lin, H., van Setten, J., Smith, A. V., Bihlmeyer, N. A., Warren, H. R., Brody, J. A., Radmanesh, F., Hall, L., Grarup, N., Müller-Nurasyid, M., Boutin, T., Verweij, N., Lin, H. J., Li-Gao, R., van den Berg, M. E., Marten, J., Weiss, S., Prins, B. P., Haessler, J., Lyytikäinen, L-P. & 81 others, Mei, H., Harris, T. B., Launer, L. J., Li, M., Alonso, A., Soliman, E. Z., Connell, J. M., Huang, P. L., Weng, L., Jameson, H. S., Hucker, W., Hanley, A., Tucker, N. R., Chen, Y. I., Bis, J. C., Rice, K. M., Sitlani, C. M., Kors, J. A., Xie, Z., Wen, C., Magnani, J. W., Nelson, C. P., Kanters, Jørgen K., Sinner, M. F., Strauch, K., Peters, A., Waldenberger, M., Meitinger, T., Bork-Jensen, J., Pedersen, Oluf Borbye, Linneberg, Allan René, Rudan, I., de Boer, R. A., van der Meer, P., Yao, J., Guo, X., Taylor, K. D., Sotoodehnia, N., Rotter, J. I., Mook-Kanamori, D. O., Trompet, S., Rivadeneira, F., Uitterlinden, A., Eijgelsheim, M., Padmanabhan, S., Smith, B. H., Völzke, H., Felix, S. B., Homuth, G., Völker, U., Mangino, M., Spector, T. D., Bots, M. L., Perez, M., Kähönen, M., Raitakari, O. T., Gudnason, V., Arking, D. E., Munroe, P. B., Psaty, B. M., van Duijn, C. M., Benjamin, E. J., Rosand, J., Samani, N. J., Hansen, Torben, Kääb, S., Polasek, O., van der Harst, P., Heckbert, S. R., Jukema, J. W., Stricker, B. H., Hayward, C., Dörr, M., Jamshidi, Y., Asselbergs, F. W., Kooperberg, C., Lehtimäki, T., Wilson, J. G., Ellinor, P. T., Lubitz, S. A. & Isaacs, A., 2018, In: Circulation. Genomic and precision medicine. 11, 5, p. 1-11 e002037.

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Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses

pjx571, pjx571, Mahendran, Y., Jonsson, Anna Elisabet, Gjesing, A. P., Weeke, P. E., Jørgensen, M. E., Færch, K., Witte, D. R., Holst, Jens Juul, Jørgensen, T., Grarup, Niels, Pedersen, Oluf Borbye, drb459, drb459, Torekov, Signe Sørensen, Kanters, Jørgen K. & Hansen, Torben, 2018, In: B M C Genetics. 19, 1, p. 1-9 9 p., 15.

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Estimating the causal effect of body mass index on hay fever, asthma and lung function using Mendelian randomization

Skaaby, T., Taylor, A. E., Thuesen, B. H., Jacobsen, R. K., Friedrich, N., Møllehave, L. T., Hansen, S., Larsen, S. C., Völker, U., Nauck, M., Völzke, H., Hansen, Torben, Pedersen, Oluf Borbye, Jørgensen, T., Paternoster, L., Munafò, M., Grarup, Niels & Linneberg, Allan René, 2018, In: Allergy. 73, 1, p. 153-164 12 p.

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Evidence of a liver-alpha cell axis in humans: hepatic insulin resistance attenuates relationship between fasting plasma glucagon and glucagonotropic amino acids

Albrechtsen, Nicolai Jacob Wewer, Færch, K., Jensen, T. M., Witte, D. R., Pedersen, Jens, Mahendran, Y., Jonsson, Anna Elisabet, Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Torekov, Signe Sørensen, Lauritzen, T., Pedersen, Oluf Borbye, Knop, Filip Krag, Hansen, Torben, Jørgensen, M. E., Vistisen, D. & Holst, Jens Juul, 2018, In: Diabetologia. 61, 3, p. 671-680

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ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals

Bihlmeyer, N. A., Brody, J. A., Smith, A. V., Warren, H. R., Lin, H., Isaacs, A., Liu, C-T., Marten, J., Radmanesh, F., Hall, L. M., Grarup, N., Mei, H., Muller-Nurasyid, M., Huffman, J. E., Verweij, N., Guo, X., Yao, J., Li-Gao, R., van den Berg, M., Weiss, S. & 30 others, Prins, B. P., van Setten, J., Haessler, J., Lyytikainen, L., Li, M., Alonso, A., Soliman, E. Z., Bis, J. C., Austin, T., Chen, Y. I., Psaty, B. M., Harrris, T. B., Launer, L. J., Padmanabhan, S., Dominiczak, A., Huang, P. L., Xie, Z., Ellinor, P. T., Kors, J. A., Campbell, A., Murray, A. D., Nelson, C. P., Tobin, M. D., Bork-Jensen, J., Hansen, Torben, Pedersen, Oluf Borbye, Linneberg, Allan René, Sinner, M. F., Peters, A. & Kanters, Jørgen K., 2018, In: Circulation. Genomic and precision medicine. 11, 1, p. 1-10 e001758.

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Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

Mahajan, A., Taliun, D., Thurner, M., Robertson, N. R., Torres, J. M., Rayner, N. W., Payne, A. J., Steinthorsdottir, V., Scott, R. A., Grarup, N., Cook, J. P., Schmidt, E. M., Wuttke, M., Sarnowski, C., Magill, R., Nano, J., Gieger, C., Trompet, S., Lecoeur, C., Preuss, M. H. & 95 others, Prins, B. P., Guo, X., Bielak, L. F., Below, J. E., Bowden, D. W., Chambers, J. C., Kim, Y. J., Ng, M. C. Y., Petty, L. E., Sim, X., Zhang, W., Bennett, A. J., Bork-Jensen, J., Brummett, C. M., Canouil, M., Kardt, K. E., Fischer, K., Kardia, S. L. R., Kronenberg, F., Lall, K., Liu, C., Locke, A. E., Luan, J., Ntalla, L., Nylander, V., Schoenherr, S., Schurmann, C., Yengo, L., Bottinger, E. P., Brandslund, I., Christensen, C., Dedoussis, G., Florez, J. C., Ford, I., France, O. H., Frayling, T. M., Giedraitis, V., Hackinger, S., Hattersley, A. T., Herder, C., Ikram, M. A., Ingelsson, M., Jorgensen, M. E., Jorgensen, T., Kriebel, J., Kuusisto, J., Ligthart, S., Lindgren, C. M., Linneberg, Allan René, Lyssenko, V., Mamakou, V., Meitinger, T., Mohlke, K. L., Morris, A. D., Nadkarni, G., Pankow, J. S., Peters, A., Sattar, N., Stancakova, A., Strauch, K., Taylor, K. D., Thorand, B., Thorleifsson, G., Thorsteinsdottir, U., Tuomilehto, J., Witte, D. R., Dupuis, J., Peyser, P. A., Zeggini, E., Loos, Ruth, Froguel, P., Ingelsson, E., Lind, L., Groop, L., Laakso, M., Collins, F. S., Jukema, J. W., Palmer, C. N. A., Grallert, H., Metspalu, A., Dehghan, A., Koettgen, A., Abecasis, G. R., Meigs, J. B., Rotter, J. I., Marchini, J., Pedersen, Oluf Borbye, Hansen, Torben, Langenberg, C., Wareham, N. J., Stefansson, K., Gloyn, A. L., Morris, A. P., Boehnke, M. & McCarthy, M. I., 2018, In: Nature Genetics. 50, 11, p. 1505-1513

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First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes

Cousminer, D. L., Ahlqvist, E., Mishra, R., Andersen, M. K., Chesi, A., Hawa, M. I., Davis, A., Hodge, K. M., Bradfield, J. P., Zhou, K., Guy, V. C., Akerlund, M., Wod, M., Fritsche, L. G., Vestergaard, H., Snyder, J., Højlund, K., Linneberg, A., Karajamaki, A., Brandslund, I. & 33 others, Kim, C. E., Witte, D., Sorgjerd, E. P., Brillon, D. J., Pedersen, Oluf Borbye, Beck-Nielsen, H., Grarup, Niels, Pratley, R. E., Rickels, M. R., Vella, A., Ovalle, F., Melander, O., Harris, R. I., Varvel, S., Grill, V. E. R., Hakonarson, H., Froguel, P., Lonsdale, J. T., Mauricio, D., Schloot, N. C., Khunti, K., Greenbaum, C. J., Asvold, B. O., Yderstraede, K. B., Pearson, E. R., Schwartz, S., Voight, B. F., Hansen, Torben, Tuomi, T., Boehm, B. O., Groop, L., Leslie, R. D. & Grant, S. F. A., 2018, In: Diabetes Care. 41, 11, p. 2396-2403

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