Ole Haagen Nielsen
Clinical Professor
Department of Clinical Medicine
Borgmester Ib Juuls Vej 1, 2730 Herlev
Denmark
Member of:
Internal Medicine: Gastroenterology and Hepatology
- 2024
Gut Microbiome and Disorders of the Gastrointestinal Tract
Hammerhøj, A., Gubatan, J. M. & Nielsen, Ole Haagen, 2024, In: Microorganisms. 12, 3, 2 p., 576.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Mirikizumab (Omvoh™) for ulcerative colitis
Hammerhøj, A., Boye, T. L., Langholz, Ebbe & Nielsen, Ole Haagen, 2024, In: Trends in Pharmacological Sciences. 45, 3, p. 281-282 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immune cell-derived signals governing epithelial phenotypes in homeostasis and inflammation
Hausmann, Annika, Steenholdt, Casper, Nielsen, Ole Haagen & Jensen, Kim Bak, 20 Mar 2024, In: Trends in Molecular Medicine. 30, 3, p. 239-251Research output: Contribution to journal › Review › Research › peer-review
- Published
Diagnosis and Pharmacological Management of Microscopic Colitis in Geriatric Care
Nielsen, Ole Haagen & Pardi, D. S., 2024, In: Drugs and Aging. 41, p. 113-123 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Updates on the management of inflammatory bowel disease from periconception to pregnancy and lactation
Nielsen, Ole Haagen, Gubatan, J. M., Kolho, K., Streett, S. E. & Maxwell, C., 30 Mar 2024, In: The Lancet. 403, 10433, p. 1291-1303Research output: Contribution to journal › Review › Research › peer-review
- Published
IAPs and RIPK1 mediate LPS-induced cytokine production in healthy subjects and Crohn's disease
Seidelin, Jakob Benedict, Jensen, Simone, Hansen, M., Bronze, M. R. D. C., Cuchet-Lourenҫo, D., Nejentsev, S., LaCasse, E. C. & Nielsen, Ole Haagen, 2024, In: Clinical and Experimental Immunology. 215, 3, p. 291–301 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Investigating the Crime Scene—Molecular Signatures in Inflammatory Bowel Disease
Andersen, V., Bennike, T. B., Bang, C., Rioux, J. D., Hébert-Milette, I., Sato, T., Hansen, Axel Kornerup & Nielsen, Ole Haagen, 2023, In: International Journal of Molecular Sciences. 24, 13, 11217.Research output: Contribution to journal › Review › Research › peer-review
- Published
Comparative onset of effect of biologics and small molecules in moderate-to-severe ulcerative colitis: a systematic review and network meta-analysis
Attauabi, M., Dahl, E. K., Burisch, J., Gubatan, J., Nielsen, Ole Haagen & Seidelin, Jakob Benedict, 2023, In: EClinicalMedicine. 57, 3, 101866.Research output: Contribution to journal › Review › Research › peer-review
- Published
Deucravacitinib (Sotyktu™) for plaque psoriasis
Granau, Agnete Marie, Boye, T. L., Jensen, Kim Bak & Nielsen, Ole Haagen, 2023, In: Trends in Pharmacological Sciences. 44, 4, p. 252-253Research output: Contribution to journal › Letter › Research › peer-review
- Published
Paternal Medications in Inflammatory Bowel Disease and Male Fertility and Reproductive Outcomes: A Systematic Review and Meta-analysis
Gubatan, J., Barber, G. E., Nielsen, Ole Haagen, Juhl, C. B., Maxwell, C., Eisenberg, M. L. & Streett, S. E., 2023, In: Clinical Gastroenterology and Hepatology. 21, 9, p. 2222-2238 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Selective JAK1 inhibitors for the treatment of inflammatory bowel disease
Nielsen, Ole Haagen, Boye, T. L., Gubatan, J., Chakravarti, D., Jaquith, J. B. & LaCasse, E. C., 2023, In: Pharmacology and Therapeutics. 245, 108402.Research output: Contribution to journal › Review › Research › peer-review
- Published
Effectiveness of Non-Budesonide Therapies in Management of Microscopic Colitis: A Systematic Review and Meta-analysis
Rehde, A., Hendel, S. K., Juhl, C. B., Gubatan, J. & Nielsen, Ole Haagen, 2023, In: Drugs. 83, 11, p. 1027-1038 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinase Signaling in Colitis-Associated Colon Cancer and Inflammatory Bowel Disease
Temby, M., Boye, T. L., Hoang, J., Nielsen, Ole Haagen & Gubatan, J., Nov 2023, In: Biomolecules. 13, 11, 14 p., 1620.Research output: Contribution to journal › Review › Research › peer-review
- 2022
- Published
Lipidomic Trajectories Characterize Delayed Mucosal Wound Healing in Quiescent Ulcerative Colitis and Identify Potential Novel Therapeutic Targets
Bjerrum, Jakob Tveiten , Wang, Y., Zhang, J., Riis, Lene Buhl, Nielsen, Ole Haagen & Seidelin, Jakob Benedict, 2022, In: International Journal of Biological Sciences. 18, 5, p. 1813-1828 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Manipulations and Intestinal Stem Cell-Derived Organoids in Inflammatory Bowel Disease
Boye, T. L., Steenholdt, Casper, Jensen, Kim Bak & Nielsen, Ole Haagen, 2022, In: Stem Cells. 40, 5, p. 447-457Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gut Microbiome in Inflammatory Bowel Disease: Role in Pathogenesis, Dietary Modulation, and Colitis-Associated Colon Cancer
Gubatan, J., Boye, T. L., Temby, M., Sojwal, R. S., Holman, D. R., Sinha, S. R., Rogalla, S. R. & Nielsen, Ole Haagen, 2022, In: Microorganisms. 10, 7, 1371.Research output: Contribution to journal › Review › Research › peer-review
- Published
Tuft Cells and Their Role in Intestinal Diseases
Hendel, S. K., Kellermann, L., Hausmann, Annika, Bindslev, Niels, Jensen, Kim Bak & Nielsen, Ole Haagen, 2022, In: Frontiers in Immunology. 13, 13 p., 822867.Research output: Contribution to journal › Review › Research › peer-review
- Published
COLAR: open-label clinical study of IL-6 blockade with tocilizumab for the treatment of immune checkpoint inhibitor-induced colitis and arthritis
Holmstroem, R. B., Nielsen, Ole Haagen, Jacobsen, Søren, Riis, Lene Buhl, Theile, S., Bjerrum, Jakob Tveiten , Vilmann, Peter, Johansen, Julia Sidenius, Boisen, M. K., Eefsen, R. H. L., Svane, Inge Marie, Nielsen, Dorte Lisbet & Chen, I. M., 2022, In: Journal for ImmunoTherapy of Cancer. 10, 9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biologics for Inflammatory Bowel Disease and their Safety in Pregnancy: A Systematic Review and Meta-analysis
Nielsen, Ole Haagen, Gubatan, J. M., Juhl, C. B., Streett, S. E. & Maxwell, C., 2022, In: Clinical Gastroenterology and Hepatology. 20, 1, p. 74-87.e3Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microscopic colitis: Etiopathology, diagnosis, and rational management
Nielsen, Ole Haagen, Fernandez-Banares, F., Sato, T. & Pardi, D. S., 1 Aug 2022, In: eLife. 11, 21 p., e79397.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reply
Nielsen, Ole Haagen, Gubatan, J. & Juhl, C. B., 2022, In: Clinical Gastroenterology and Hepatology. 20, 4, p. 963-964Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Selective tyrosine kinase 2 inhibitors in inflammatory bowel disease
Nielsen, Ole Haagen, Boye, T. L., Chakravarti, D. & Gubatan, J., 2022, In: Trends in Pharmacological Sciences. 43, 5, p. 424-436Research output: Contribution to journal › Review › Research › peer-review
- Published
Multiparametric and accurate functional analysis of genetic sequence variants using CRISPR-Select
Niu, Yiyuan, Ferreira Azevedo, Catarina A, Li, Xin, Kamali, E., Nielsen, Ole Haagen, Sørensen, Claus Storgaard & Frödin, Morten, 2022, In: Nature Genetics. 54, 28 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of fibre and red/processed meat intake on treatment outcomes among patients with chronic inflammatory diseases initiating biological therapy: A prospective cohort study
Overgaard, S. H., Sørensen, S. B., Munk, H. L., Nexøe, A. B., Glerup, H., Henriksen, R. H., Guldmann, T., Pedersen, N., Saboori, S., Hvid, L., Dahlerup, J. F., Hvas, C. L., Jawhara, M., Andersen, K. W., Pedersen, A. K., Nielsen, O. H., Bergenheim, F., Brodersen, J. B., Heitmann, B. L., Halldorsson, T. I. & 6 others, , 2022, In: Frontiers in Nutrition. 9, 13 p., 985732.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
IBD metabonomics predicts phenotype, disease course, and treatment response
Bjerrum, Jakob Tveiten , Wang, Y. L., Seidelin, Jakob Benedict & Nielsen, Ole Haagen, 2021, In: EBioMedicine. 71, 103551.Research output: Contribution to journal › Review › Research › peer-review
- Published
Telomere dysfunction instigates inflammation in inflammatory bowel disease
Chakravarti, D., Lee, R., Multani, A. S., Santoni, A., Keith, Z., Hsu, W. H., Chang, K., Reyes, L., Rashid, A., Wu, C. J., Li, J., Zhang, J., Shim, H. S., Chandra, K., Deng, P., Spring, D. J., Nielsen, O. H., Riis, L. B., Mayigegowda, K. K., Blutt, S. E. & 9 others, , 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 29, e2024853118.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biologics During Pregnancy in Women With Inflammatory Bowel Disease and Risk of Infantile Infections: A Systematic Review and Meta-Analysis
Gubatan, J. M., Nielsen, Ole Haagen, Levitte, S., Juhl, C. B., Maxwell, C., Streett, S. E. & Habtezion, A., 2021, In: Am J Gastroenterol. 116, 2, p. 243-253Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification, isolation and analysis of human gut-associated lymphoid tissues
Jørgensen, P. B., Fenton, T. M., Mörbe, U. M., Riis, Lene Buhl, Jakobsen, H. L., Nielsen, Ole Haagen & Agace, W. W., 22 Feb 2021, In: Nature Protocols. 16, p. 2051–2067Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
A fully defined 3D matrix for ex vivo expansion of human colonic organoids from biopsy tissue
Bergenheim, F., Fregni, G., Buchanan, C. F., Riis, Lene Buhl, Heulot, M., Touati, J., Seidelin, Jakob Benedict, Rizzi, S. C. & Nielsen, Ole Haagen, 2020, In: Biomaterials. 262, 11 p., 120248.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Telomere dysfunction activates YAP1 to drive tissue inflammation
Chakravarti, D., Hu, B., Mao, X., Rashid, A., Li, J., Li, J., Liao, W. T., Whitley, E. M., Dey, P., Hou, P., LaBella, K. A., Chang, A., Wang, G., Spring, D. J., Deng, P., Zhao, D., Liang, X., Lan, Z., Lin, Y., Sarkar, S. & 16 others, , 2020, In: Nature Communications. 11, 13 p., 4766.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immune Profiling of Human Gut-Associated Lymphoid Tissue Identifies a Role for Isolated Lymphoid Follicles in Priming of Region-Specific Immunity
Fenton, T. M., Jørgensen, P. B., Niss, K., Rubin, S. J. S., Mörbe, U. M., Riis, Lene Buhl, Da Silva, C., Plumb, A., Vandamme, J., Jakobsen, H. L., Brunak, Søren, Habtezion, A., Nielsen, Ole Haagen, Johansson-Lindbom, B. & Agace, W. W., 2020, In: Immunity. 52, 3, p. 557-570, e1-e6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SMAC mimetics and RIPK inhibitors as therapeutics for chronic inflammatory diseases
Jensen, S., Seidelin, Jakob Benedict, LaCasse, E. C. & Nielsen, Ole Haagen, 2020, In: Science Signaling. 13, 619, 18 p., eaax8295.Research output: Contribution to journal › Review › Research › peer-review
- Published
Mucosal vitamin D signaling in inflammatory bowel disease
Kellermann, L., Jensen, Kim Bak, Bergenheim, F., Gubatan, J., Chou, N. D., Moss, A. & Nielsen, Ole Haagen, 2020, In: Autoimmunity Reviews. 19, 11, 102672.Research output: Contribution to journal › Review › Research › peer-review
- Published
Efficacy and safety of methotrexate in the management of inflammatory bowel disease: A systematic review and meta-analysis of randomized, controlled trials
Nielsen, Ole Haagen, Steenholdt, C., Juhl, C. B. & Rogler, G., Mar 2020, In: EClinicalMedicine. 20, 10 p., 100271.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Fluorescence-based tracing of transplanted intestinal epithelial cells using confocal laser endomicroscopy
Bergenheim, F., Seidelin, Jakob Benedict, Pedersen, M. T., Mead, B. E., Jensen, Kim Bak, Karp, J. M. & Nielsen, Ole Haagen, 2019, In: Stem Cell Research & Therapy. 10, 1, p. 1-12 12 p., 148.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabonomics in gastroenterology and hepatology
Bjerrum, Jakob Tveiten & Nielsen, Ole Haagen, 1 Aug 2019, In: International Journal of Molecular Sciences. 20, 15, 3638.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Systematic review with meta-analysis: association of vitamin D status with clinical outcomes in adult patients with inflammatory bowel disease
Gubatan, J., Chou, N. D., Nielsen, Ole Haagen & Moss, A. C., 2019, In: Alimentary Pharmacology and Therapeutics. 50, 11-12, p. 1146-1158 13 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Biosimilars for management of Crohn disease
Nielsen, Ole Haagen & Ainsworth, M. A., 2019, In: Annals of Internal Medicine. 170, 2, p. 129-130 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Managing vitamin D deficiency in inflammatory bowel disease
Nielsen, Ole Haagen, Hansen, T. I., Gubatan, J. M., Jensen, Kim Bak & Rejnmark, L., 2019, In: Frontline Gastroenterology. 10, 4, p. 394-400 7 p., 31656565.Research output: Contribution to journal › Review › Research › peer-review
- Published
Methotrexate for inflammatory bowel disease: time for reconsideration
Nielsen, Ole Haagen, Ainsworth, M. A. & Steenholdt, Casper, 2019, In: Expert Review of Gastroenterology and Hepatology. 13, 5, p. 407-409 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
- 2018
- Published
Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
Boyd, M., Thodberg, M., Vitezic, M., Lange, J. B., Vitting-Seerup, K., Chen, Y., Coskun, M., Li, Y., Lo, B. Z. S., Klausen, P., Schweiger, P., Pedersen, A. G., Rapin, N. P. J-P., Skovgaard, K., Dahlgaard, K., Andersson, R., Terkelsen, T. B., Lilje, B., Troelsen, J. T., Petersen, A. M. & 7 others, , 2018, In: Nature Communications. 9, 19 p., 1661.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of red and processed meat and fibre intake on treatment outcomes among patients with chronic inflammatory diseases: protocol for a prospective cohort study of prognostic factors and personalised medicine
Christensen, R., Heitmann, B. L., Andersen, K. W., Nielsen, O. H., Sørensen, S. B., Jawhara, M., Bygum, A., Hvid, L., Grauslund, J., Wied, J., Glerup, H., Fredberg, U., Villadsen, J. A., Kjær, S. G., Fallingborg, J., Moghadd, S. A. G. R., Knudsen, T., Brodersen, J., Frøjk, J., Dahlerup, J. F. & 21 others, , 2018, In: BMJ Open. 8, 2, 15 p., :e018166.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intestinal barrier integrity and inflammatory bowel disease: Stem cell-based approaches to regenerate the barrier
Holmberg, F. E. O., Pedersen, J., Jørgensen, P., Soendergaard, C., Jensen, Kim Bak & Nielsen, Ole Haagen, Apr 2018, In: Journal of Tissue Engineering and Regenerative Medicine. 12, 4Research output: Contribution to journal › Review › Research › peer-review
- Published
COX-2-PGE2 Signaling Impairs Intestinal Epithelial Regeneration and Associates with TNF Inhibitor Responsiveness in Ulcerative Colitis
Li, Yuan, Soendergaard, C., Bergenheim, F. H., Aronoff, D. M., Milne, G., Riis, Lene Buhl, Seidelin, Jakob Benedict, Jensen, Kim Bak & Nielsen, Ole Haagen, 2018, In: EBioMedicine. 36, p. 497-507Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rational Management of Iron-Deficiency Anaemia in Inflammatory Bowel Disease
Nielsen, Ole Haagen, Soendergaard, C., Vikner, M. E. & Weiss, G., 2018, In: Nutrients. 10, 1, 25 p., 82.Research output: Contribution to journal › Review › Research › peer-review
- Published
Role of Vitamin D in the Natural History of Inflammatory Bowel Disease
Nielsen, Ole Haagen, Rejnmark, L. & Moss, A. C., 2018, In: Journal of Crohn's and Colitis. 12, 6, p. 742-752 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Putative biomarkers of vedolizumab resistance and underlying inflammatory pathways involved in IBD
Soendergaard, C., Seidelin, Jakob Benedict, Steenholdt, C. & Nielsen, Ole Haagen, 2018, In: B M J Open Gastroenterology. 5, 1, e000208.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting JAK-STAT signal transduction in IBD
Soendergaard, C., Bergenheim, F. H., Bjerrum, Jakob Tveiten & Nielsen, Ole Haagen, 2018, In: Pharmacology & Therapeutics. 192, p. 100-111Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inflammatory bowel disease with primary sclerosing cholangitis: A Danish population-based cohort study 1977-2011
Sørensen, J. Ø., Nielsen, Ole Haagen, Andersson, M., Ainsworth, M. A., Ytting, H., Bélard, E. & Jess, T., 2018, In: Liver International. 38, 3, p. 532-541Research output: Contribution to journal › Journal article › Research › peer-review
- Published
YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration
Yui, S., Azzolin, L., Maimets, Martti, Pedersen, M. T., Fordham, R. P., Hansen, Stine Lind, Larsen, Hjalte List, Guiu, J., Alves, M. R. P., Friis, Carsten, Johansen, Jens Vilstrup, Li, Yuan, Madsen, C. D., Nakamura, T., Watanabe, M., Nielsen, Ole Haagen, Schweiger, P. J., Piccolo, S. & Jensen, Kim Bak, 1 Jan 2018, In: Cell Stem Cell. 22, 1, p. 35-49. e7 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4947702
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Identification of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2
Research output: Contribution to journal › Journal article › Research › peer-review
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Modulation of Gut Microbiota in Pathological States
Research output: Contribution to journal › Review › Research › peer-review
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YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration
Research output: Contribution to journal › Journal article › Research › peer-review
Published