Jesper Østergaard
Professor
Pharmaceutical Physical and Analytical Chemistry
Universitetsparken 2, 2100 København Ø
- Published
Cisplatin Encapsulation Generates Morphologically Different Multicompartments in the Internal Nanostructures of Nonlamellar Liquid-Crystalline Self-Assemblies
Azmi, I. D. M., Østergaard, Jesper, Stürup, Stefan, Gammelgaard, Bente, Urtti, A., Moghimi, S. M. & Yaghmur, Anan, 5 Jun 2018, In: Langmuir : the ACS journal of surfaces and colloids. 34, 22, p. 6570-6581 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biorelevant Dissolution of Dipyridamole and Piroxicam Using an Automated UV/Vis Spectrophotometric and Potentiometric Dissolution Testing Platform
Berthelsen, R., Larsen, Susan Weng, Mullertz, Anette , Box, K. & Østergaard, Jesper, 2023, In: Dissolution Technologies. 30, 3, p. 144-153Research output: Contribution to journal › Journal article › Research › peer-review
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Development of UV-Vis Imaging Compatible Chromatographic Matrix with Application for Injectable Formulation Characterization
Bock, Frederik, Hu, A., Cicale, V., Larsen, Susan Weng, Lu, X. & Østergaard, Jesper, 2023, In: Analytical Chemistry. 95, 43, p. 15861–15866Research output: Contribution to journal › Journal article › Research › peer-review
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Towards in vitro in vivo correlation for modified release subcutaneously administered insulins
Bock, Frederik, Lin, E., Larsen, C., Jensen, H., Huus, K., Larsen, Susan Weng & Østergaard, Jesper, 2020, In: European Journal of Pharmaceutical Sciences. 145, 10 p., 105239.Research output: Contribution to journal › Journal article › Research › peer-review
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Methodological Considerations in Development of UV Imaging for Characterization of Intra-Tumoral Injectables Using cAMP as a Model Substance
Bock, Frederik, Bøtker, Johan Peter, Larsen, Susan Weng, Lu, X. & Østergaard, Jesper, 2022, In: International Journal of Molecular Sciences. 23, 7, 18 p., 3599.Research output: Contribution to journal › Journal article › Research › peer-review
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Insights into the early dissolution events of amlodipine using UV imaging and Raman spectroscopy
Bøtker, Johan Peter, Savolainen, M., Koradia, V., Tian, F., Rades, Thomas, Mullertz, Anette , Cornett, Claus, Rantanen, Jukka & Østergaard, Jesper, 2011, In: Molecular Pharmaceutics. 8, 4, p. 1372-1380 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An investigation of drug compact topography as relates to intrinsic dissolution rates determined by dissolution imaging
Brown, B., Fazili, Z., Ward, A., Walton, K., Blunt, L., Østergaard, Jesper & Asare-Addo, K., 2021, In: Journal of Drug Delivery Science and Technology. 61, 10 p., 102143.Research output: Contribution to journal › Journal article › Research › peer-review
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Application of UV dissolution imaging to pharmaceutical systems
Brown, B., Ward, A., Fazili, Z., Østergaard, Jesper & Asare-Addo, K., 2021, In: Advanced Drug Delivery Reviews. 177, 26 p., 113949.Research output: Contribution to journal › Review › Research › peer-review
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A new approach to dissolution testing by UV imaging and finite element simulations
Bøtker, Johan Peter, Rantanen, Jukka, Rades, Thomas, Mullertz, Anette , Østergaard, Jesper & Jensen, H., 2013, In: Pharmaceutical Research. 30, 5, p. 1328-1337Research output: Contribution to journal › Journal article › Research › peer-review
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Limits in Size of Taylor Dispersion Analysis: Representation of the Different Hydrodynamic Regimes and Application to the Size-Characterization of Cubosomes
Chamieh, J., Leclercq, L., Martin, M., Slaoui, S., Jensen, H., Østergaard, Jesper & Cottet, H., 2017, In: Analytical Chemistry. 89, 24, p. 13487-13493Research output: Contribution to journal › Journal article › Research › peer-review
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Matrix effects in nilotinib formulations with pH-responsive polymer produced by carbon dioxide-mediated precipitation
Colombo, S., Brisander, M., Haglöf, J., Sjövall, P., Andersson, P., Østergaard, Jesper & Malmsten, M., 15 Oct 2015, In: International Journal of Pharmaceutics. 494, 1, p. 205-217 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Selective analysis of human serum albumin based on SEC-ICP-MS after labelling with iophenoxic acid
Dersch, J. M., Nguyen, T. T. T. N., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, Apr 2015, In: Analytical and Bioanalytical Chemistry. 407, 10, p. 2829-36 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of a-cyclodextrin on drug distribution studied by electrochemistry at interfaces between immiscible electrolyte solutions
Deryabina, M., Hansen, S. H., Østergaard, Jesper & Jensen, H., 2009, In: Journal of Physical Chemistry A. 113, p. 7263-7269Research output: Contribution to journal › Journal article › Research › peer-review
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An interlaboratory investigation of intrinsic dissolution rate determination using surface dissolution
Etherson, K., Dunn, C., Matthews, W., Pamelund, H., Barragat, C., Sanderson, N., Izumi, T., Mathews, C. D. C., Halbert, G., Wilson, C., McAllister, M., Mann, J., Østergaard, Jesper, Butler, J. & Khadra, I., 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 150, p. 24-32 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Liposomer i lægemiddelforskning
Franzen, U., Jørgensen, Lene, Larsen, C. S., Jensen, H. & Østergaard, Jesper, 2007, In: Lægemiddelforskning. p. 14-15Research output: Contribution to journal › Journal article › Communication
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Determination of liposome-buffer distribution coefficients of charged drugs by capillary electrophoresis frontal analysis
Franzen, U., Jørgensen, Lene, Larsen, C. S., Heegaard, N. H. H. & Østergaard, Jesper, 2009, In: Electrophoresis. 30, 15, p. 2711-2719Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of a liposome-based formulation of oxaliplatin using capillary electrophoresis: encapsulation and leakage
Franzen, U., Nguyen, T. T. N. T., Vermehren, C., Gammelgaard, Bente & Østergaard, Jesper, 2011, In: Journal of Pharmaceutical and Biomedical Analysis. 55, 1, p. 16-22Research output: Contribution to journal › Journal article › Research › peer-review
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Physicochemical characterization of a PEGylated liposomal drug formulation using capillary electrophoresis
Franzen, U., Vermehren, C., Jensen, H. & Østergaard, Jesper, 2011, In: Electrophoresis. 32, 6-7, p. 738-748Research output: Contribution to journal › Journal article › Research › peer-review
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Physico-chemical characterization of liposomes and drug substance-liposome interactions in pharmaceutics using capillary electrophoresis and electrokinetic chromatography
Franzen, U. & Østergaard, Jesper, Dec 2012, In: Journal of Chromatography A. 1267, p. 32-44 13 p.Research output: Contribution to journal › Review › Research › peer-review
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Intra-articular drug disapperance kinetics: Reducing the number of in vivo experiments from establishment of an in vitro-in vivo correlation?
Frost, A. B., Jacobsen, Stine, Thomsen, M. H., Lindegaard, Casper, Larsen, Susan Weng, Østergaard, Jesper, Andersen, P. H. & Larsen, C. S., 2008. 1 p.Research output: Contribution to conference › Poster › Research
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Nye depotlægemidler til injektion i gigtramte led: kan laboratoriemodeller reducere antallet af dyreforsøg
Frost, A. B., Larsen, Susan Weng, Østergaard, Jesper & Larsen, C. S., 2008, In: Lægemiddelforskning. p. 46-48Research output: Contribution to journal › Journal article › Communication
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The pharmacokinetics of the weakly protein-bound anionic compound diatrizoate in serum and synovial fluid of the horse
Frost, A. B., Larsen, F., Larsen, Susan Weng, Østergaard, Jesper, Thomsen, M. H., Stürup, Stefan, Andersen, P. H. & Larsen, C. S., 2010, In: Pharmaceutical Research. 27, 1, p. 143-150 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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On the search for in vitro in vivo correlations in the field of intra-articular drug delivery: Administration of sodium diatrizoate to the horse
Frost, A. B., Larsen, F., Østergaard, Jesper, Larsen, Susan Weng, Lindegaard, Casper, Hansen, H. R. & Larsen, C. S., 2010, In: European Journal of Pharmaceutical Sciences. 41, p. 10-15Research output: Contribution to journal › Journal article › Research › peer-review
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Intra-articular injection of morphine to the horse: Establishment of an in vitro-in vivo relationship
Frost, A. B., Lindegaard, Casper, Larsen, F., Østergaard, Jesper, Larsen, Susan Weng & Larsen, C. S., 2011, In: Drug Development and Industrial Pharmacy. 37, 9, p. 1043-1048Research output: Contribution to journal › Journal article › Research › peer-review
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Real-time in vitro dissolution of 5-aminosalicylic acid from single ethyl cellulose coated extrudates studied by UV imaging
Gaunø, M. H., Vilhelmsen, T., Larsen, C. C., Bøtker, Johan Peter, Wittendorff, J., Rantanen, Jukka & Østergaard, Jesper, Sep 2013, In: Journal of Pharmaceutical and Biomedical Analysis. 83, p. 49-56 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Real-time dissolution behavior of furosemide in biorelevant media as determined by UV imaging
Gordon, S., Naelapää, K., Rantanen, Jukka, Selen, A., Mullertz, Anette & Østergaard, Jesper, 2013, In: Pharmaceutical Development and Technology. 18, 6, p. 1407-16 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of selenium nanoparticles in human plasma by capillary electrophoresis hyphenated to inductively coupled plasma mass spectrometry
Gronbaek-Thorsen, F., Hansen, R. H., Østergaard, Jesper, Gammelgaard, Bente & Moller, L. H., 2021, In: Analytical and Bioanalytical Chemistry. 413, 8, p. 2247-2255Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of external calibration and isotope dilution LC-ICP-MS/MS for quantitation of oxytocin and its selenium analogue in human plasma
Grønbæk-Thorsen, F., Jensen, C., Østergaard, Jesper, Møller, L. H. & Gammelgaard, Bente, 2021, In: Analytical and Bioanalytical Chemistry. 413, p. 6479–6488Research output: Contribution to journal › Journal article › Research › peer-review
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Protein adsorption at charged surfaces: the role of electrostatic interactions and interfacial charge regulation
Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, Henrik Elvang, 15 Mar 2011, In: Langmuir. 27, 6, p. 2634-2643 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Formation of dielectric layers and charge regulation in protein adsorption at biomimetic interfaces
Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, H., 2012, In: Langmuir. 28, 3, p. 1804-1815Research output: Contribution to journal › Journal article › Research › peer-review
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Interfacial complexes between a protein and lipophilic ions at an oil - water interface
Hartvig, R. A., Méndez, M. A., van de Weert, Marco, Jørgensen, Lene, Østergaard, Jesper, Girault, H. H. & Jensen, H., 2010, In: Analytical Chemistry. 82, 18, p. 7699-7705Research output: Contribution to journal › Journal article › Research › peer-review
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Protein adsorption at charged surfaces: The role of electrostatic interactions and interacial charge regulation
Hartvig, R. A., van de Weert, Marco, Østergaard, Jesper, Jørgensen, Lene & Jensen, H., 2011, In: Langmuir. 27, p. 2634-2643Research output: Contribution to journal › Journal article › Research › peer-review
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Exploration of in vitro drug release testing methods for saquinavir microenvironmental pH modifying buccal films
He, S., Jacobsen, Jette, Nielsen, C. U., Genina, Natalja, Østergaard, Jesper & Mu, Huiling, 2021, In: European Journal of Pharmaceutical Sciences. 163, 10 p., 105867.Research output: Contribution to journal › Journal article › Research › peer-review
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Microenvironmental pH modifying films for buccal delivery of saquinavir: Effects of organic acids on pH and drug release in vitro
He, S., Østergaard, Jesper, Ashna, M., Nielsen, C. U., Jacobsen, Jette & Mu, Huiling, 2020, In: International Journal of Pharmaceutics. 585, 10 p., 119567.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of proteins in solution using affinity capillary electrophoresis
Heegaard, N. H. H., Schou, C. & Østergaard, Jesper, 2008, Affinity chromatography: methods and protocols. Zachariou, M. (ed.). 2 ed. USA: Humana Press, p. 303-338Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Characterization of the complexation of tauro- and glyco-conjugated bile salts with ¿-cyclodextrin and 2-hydroxypropyl-¿-cyclodextrin using affinity capillary electrophoresis
Holm, R., Hartvig, R. A., Nicolajsen, H. V., Westh, P. & Østergaard, Jesper, 2008, In: Journal of Inclusion Phenomena and Macrocyclic Chemistry. 61, 1-2, p. 161 - 169Research output: Contribution to journal › Journal article › Research › peer-review
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Complexation of tauro- and glycoconjugated bile salts with a-cyclodextrin and hydroxypropyl-a-cyclodextrin studied by affinity capillary electrophoresis and molecular modelling
Holm, R., Schönbeck, C., Askjær, S., Jensen, H., Westh, P. & Østergaard, Jesper, 2011, In: Journal of Separation Science. 34, 22, p. 3221-3230Research output: Contribution to journal › Journal article › Research › peer-review
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Determination of stability constants of tauro- and glyco-conjugated bile salts with the negatively charged sulfobutylether-β-cyclodextrin: comparison of affinity capillary electrophoresis and isothermal titration calorimetry and thermodynamic analysis of the interaction
Holm, R., Østergaard, Jesper, Schönbeck, C., Jensen, H., Shi, W., Peters, G. H. & Westh, P., Apr 2014, In: Journal of Inclusion Phenomena and Macrocyclic Chemistry. 78, 1-4, p. 185-194Research output: Contribution to journal › Journal article › Research › peer-review
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Complexation of tauro- and glyco-conjugated bile salts with three neutral ß-CDs studied by ACE
Holm, R., Nicolajsen, H. V., Hartvig, R. A., Westh, P. & Østergaard, Jesper, 2007, In: Electrophoresis. 28, 20, p. 3745-3752Research output: Contribution to journal › Journal article › Research › peer-review
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Selenium as an alternative peptide label - comparison to fluorophore-labelled penetratin
Hyrup Møller, L., Bahnsen, J. S., Nielsen, Hanne Mørck, Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 25 Jan 2015, In: European Journal of Pharmaceutical Sciences. 67, p. 76-84 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Manipulating Aggregation Behavior of the Uncharged Peptide Carbetocin
Høgstedt, U. B., Østergaard, Jesper, Weiss, T., Sjögren, H. & van de Weert, Marco, Mar 2018, In: Journal of Pharmaceutical Sciences. 107, 3, p. 838-847 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Taylor Dispersion Analysis as a promising tool for assessment of peptide-peptide interactions
Høgstedt, U. B., Schwach, G., van de Weert, Marco & Østergaard, Jesper, 25 Jul 2016, In: European Journal of Pharmaceutical Sciences. 93, p. 21-28 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Physicochemical profiling of drug candidates using capillary-based techniques
Jensen, H., Larsen, Susan Weng, Larsen, C. S. & Østergaard, Jesper, 2013, In: Journal of Drug Delivery Science and Technology. 23, p. 333-345Research output: Contribution to journal › Journal article › Research › peer-review
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Flow induced dispersion analysis quantifies noncovalent interactions in nanoliter samples
Jensen, H. & Østergaard, Jesper, 2010, In: Journal of the American Chemical Society. 132, 12, p. 4070-4071Research output: Contribution to journal › Journal article › Research › peer-review
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CE frontal analysis employing contactless conductivity detection for determination of CMCs of non-UV absorbing charged surfactants
Jensen, H., Østergaard, Jesper & Hansen, S. H., 2007, In: Electrophoresis. 28, 17, p. 2975-2980Research output: Contribution to journal › Journal article › Research › peer-review
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Elektrokemi til karakterisering og kvantitativ analyse af lægemiddelstoffer
Jensen, H., Deryabina, M., Hansen, S. H. & Østergaard, Jesper, 2009, In: Lægemiddelforskning.Research output: Contribution to journal › Journal article › Research
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CE frontal analysis based on simultaneous UV and contactless conductivity detection: a general setup for studying noncovalent interactions
Jensen, H., Østergaard, Jesper, Thomsen, A. E. & Hansen, S. H., 2007, In: Electrophoresis. 28, 3, p. 322-327Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of Cu-amyloid-β by using bifunctional peptides with β-sheet breaker and chelator moieties
Jensen, M., Canning, A., Chiha, S., Bouquerel, P., Pedersen, J. T., Østergaard, Jesper, Cuvillier, O., Sasaki, I., Hureau, C. & Faller, P., 2012, In: Chemistry: A European Journal. 18, 16, p. 4836-4839 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Performance characteristics of UV imaging instrumentation for diffusion, dissolution and release testing studies
Jensen, S. S., Jensen, H., Goodall, D. M. & Østergaard, Jesper, 30 Nov 2016, In: Journal of Pharmaceutical and Biomedical Analysis. 131, p. 113-123 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Real-time UV imaging identifies the role of pH in insulin dissolution behavior in hydrogel-based subcutaneous tissue surrogate
Jensen, S. S., Jensen, H., Cornett, Claus, Møller, E. H. & Østergaard, Jesper, 10 Mar 2015, In: European Journal of Pharmaceutical Sciences. 69, p. 26-36 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1299275
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Quantification of pharmaceutical peptides in human plasma by LC-ICP-MS sulfur detection
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Application of UV Imaging in Formulation Development
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Performance characteristics of UV imaging instrumentation for diffusion, dissolution and release testing studies
Research output: Contribution to journal › Journal article › Research › peer-review
Published