Jens Lykkesfeldt

Jens Lykkesfeldt

Professor

Member of:

  • Lifepharm

ORCID: 0000-0002-6514-8407

Publication year:
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51 - 100 out of 270Page size: 50
  1. 2020
  2. Published

    Insulin Treatment Attenuates Small Nerve Fiber Damage in Rat Model of Type 2 Diabetes

    Andreasen, L. J., Kirk, R. K., Fledelius, C., Yorek, M. A., Lykkesfeldt, Jens & Akerstrom, T., 2020, In: Journal of Diabetes Research. 2020, 13 p., 9626398.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Malnutrition predisposes to endotoxin-induced edema and impaired inflammatory response in parenterally fed piglets

    Bæk, Ole, Fabiansen, C., Friis, Henrik, Ritz, C., Koch, Jørgen, Willesen, Jakob, Heegaard, P. M. H., Lykkesfeldt, Jens, Briend, A., Golden, M. H., Sangild, Per Torp & Thymann, Thomas, 2020, In: Journal of Parenteral and Enteral Nutrition. 44, 4, p. 668-676

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    On the effect of vitamin C intake on human health: How to (mis)interprete the clinical evidence

    Lykkesfeldt, Jens, 2020, In: Redox Biology. 34, 13 p., 101532.

    Research output: Contribution to journal › Review › Research › peer-review

  5. Published

    Pharmacokinetics of Repeated Oral Dosing with Coenzyme Q10 in Cavalier King Charles Spaniels with Myxomatous Mitral Valve Disease

    Christiansen, L. B., Morsing, Malene Kjelin, Reimann, Maria Josefine, Martinussen, Torben, Birlie, Z., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2020, In: Antioxidants. 9, 9 p., 827.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Salmon calcitonin distributes into the arcuate nucleus to a subset of NPY neurons in mice

    Zakariassen, Hannah Louise, John, L. M., Lykkesfeldt, Jens, Raun, K., Glendorf, T., Schaffer, L., Lundh, S., Secher, A., Lutz, T. A. & Le Foll, C., 2020, In: Neuropharmacology. 167, 107987.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Subcutaneous Administration of Insulin is Associated With Regional Differences in Injection Depot Variability and Kinetics in The Rat

    Gradel, Anna Katrina Jógvansdóttir, Porsgaard, T., Lykkesfeldt, Jens, Brockhoff, P. M. B., Seested, T. & Refsgaard, H. H. F., 2020, In: Experimental and Clinical Endocrinology and Diabetes. 128, 5, p. 332-338 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Variation in diagnostic NAFLD/NASH read-outs in paired liver samples from rodent models

    Jensen, Victoria Svop, Tveden-Nyborg, Pernille, Zacho-Rasmussen, C., Quaade, Michelle Lauge, Ipsen, David Højland, Hvid, H., Fledelius, C., Wulff, E. M. & Lykkesfeldt, Jens, 2020, In: Journal of Pharmacological and Toxicological Methods. 101, 9 p., 106651.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. 2019
  10. Published

    Oral vitamin C supplementation to patients with myeloid cancer on azacitidine treatment: Normalization of plasma vitamin C induces epigenetic changes

    Gillberg, Linn, mxz703, mxz703, Nasif, A., Ohtani, H., Madaj, Z., Hansen, Jakob Werner, Rapin, N., Mogensen, J. B., Liu, M., Dufva, I. H., Lykkesfeldt, Jens, Hajkova, P., Jones, P. A. & Grønbæk, Kirsten, 17 Oct 2019, In: Clinical Epigenetics. 11, 1, p. 143-153 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    A role of peroxisome proliferator-activated receptor gamma in non-alcoholic fatty liver disease

    Skat-Rørdam, Josephine, Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, May 2019, In: Basic & Clinical Pharmacology & Toxicology. 124, 5, p. 528-537

    Research output: Contribution to journal › Review › Research › peer-review

  12. Published

    Peri-operative endothelial dysfunction in patients undergoing minor abdominal surgery: An observational study

    Busch, S. V. E., Godthaab, C., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Gögenur, I., Feb 2019, In: European Journal of Anaesthesiology. 36, 2, p. 130-134 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    An ELISA for detection of complement-bound circulating immune complexes in mice

    Boysen, L., Lauritzen, B., Viuff, B. M., Lykkesfeldt, Jens & Landsy, L. H., 2019, In: Journal of Immunotoxicology. 16, 1, p. 82-86 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Antioxidant supplementation for lung disease in cystic fibrosis

    Ciofu, Oana, Smith, S. & Lykkesfeldt, Jens, 2019, In: Cochrane Database of Systematic Reviews. 2019, 10, CD007020.

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    Atorvastatin and vitamin e accelerates NASH resolution by dietary intervention in a preclinical guinea pig model

    Klaebel, J. H., Skjødt, M., Skat-Rørdam, Josephine, Rakipovski, G., Ipsen, David Højland, Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Nutrients. 11, 11, 20 p., 2834.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Delayed insulin absorption correlates with alterations in subcutaneous depot kinetics in rats with diet‐induced obesity

    Gradel, Anna Katrina Jógvansdóttir, Porsgaard, T., Brockhoff, P. M. B., Seested, T., Lykkesfeldt, Jens & Refsgaard, H. H. F., 2019, In: Obesity Science & Practice. 5, 3, p. 281-288

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Determination of reduced and oxidized coenzyme Q10 in canine plasma and heart tissue by HPLC-ECD: Comparison with LC-MS/MS quantification

    Schou-Pedersen, A. M. V., Schemeth, D. & Lykkesfeldt, Jens, 2019, In: Antioxidants. 8, 8, 253.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Expression of endothelin type B receptors in uterine artery smooth muscle cells from pregnant Guinea pigs

    Skovsted, Gry Freja, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2019, In: Placenta. 77, p. 8-15 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Formation and glomerular deposition of immune complexes in mice administered bovine serum albumin: Evaluation of dose, frequency, and biomarkers

    Boysen, L., Viuff, B. M., Landsy, L. H., Price, S. A., Raymond, J. T., Lykkesfeldt, Jens & Lauritzen, B., 2019, In: Journal of Immunotoxicology. 16, 1, p. 191-200 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Generic immune complex assay for detection of murine anti-drug-antibodies in complex with human IgG

    Boysen, L., Sprinkel, A. M. E., Lauritzen, B., Breinholt, J., Lykkesfeldt, Jens, Viuff, B. M. & Landsy, L. H., 2019, In: Biologicals. 60, p. 42-48 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Glycemic control during pregnancy — A predictor of vitamin C status at labor in type 1 diabeticwomen?

    Juhl, B., Lauszus, F. F. & Lykkesfeldt, Jens, 2019, In: Antioxidants. 8, 6, 153.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Molecular drivers of non-alcoholic steatohepatitis are sustained in mild-to-late fibrosis progression in a guinea pig model

    Ipsen, David Højland, Skat-Rørdam, Josephine, Tsamouri, M. M., Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Molecular Genetics and Genomics. 294, 3, p. 649–661

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Når leveren bliver for fed

    Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Aktuel Naturvidenskab. 2019, 3, p. 28-31

    Research output: Contribution to journal › Journal article › Communication

  24. Published

    Telomere length and genotoxicity in the lung of rats following intragastric exposure to food-grade titanium dioxide and vegetable carbon particles

    Jensen, Ditte Marie, Løhr, M., Sheykhzade, Majid, Lykkesfeldt, Jens, Wils, Regitze Sølling, Loft, Steffen & Møller, Peter, 2019, In: Mutagenesis. 34, 2, p. 203-214 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The Pharmacokinetics of Vitamin C

    Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Nutrients. 11, 10, 20 p., 2412.

    Research output: Contribution to journal › Review › Research › peer-review

  26. Published

    The effect of melatonin on endothelial dysfunction in patients after acute coronary syndrome: The MEFACS randomized clinical trial

    Zahid, J. A., Isbrand, A., Kleif, J., Schou-Pedersen, A. V., Lykkesfeldt, Jens, Madsen, M. T. & Gögenur, Ismail, 2019, In: Journal of Pineal Research. 67, 3, e12600.

    Research output: Contribution to journal › Letter › Research › peer-review

  27. Published

    Towards a Göttingen minipig model of adult onset growth hormone deficiency: evaluation of stereotactic electrocoagulation method

    Ørstrup, Laura Kofoed Hvidsten, Tvilling, L., Orlowski, D., Zaer, H., Bjarkam, C. R., von Voss, P., Andersen, P. S., Christoffersen, B., Hedemann Sørensen, J. C., Laursen, T., Thygesen, P., Lykkesfeldt, Jens & Glud, A. N., 2019, In: Heliyon. 5, 11, 8 p., e02892.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. 2018
  29. Published

    Effect of maternal hypoglycaemia during gestation on materno-foetal nutrient transfer and embryo-foetal development: Evidence from experimental studies focused primarily on the rat

    Jensen, Vivi Flou Hjorth, Mølck, A. M., Lykkesfeldt, Jens & Bøgh, I. B., Apr 2018, In: Reproductive Toxicology. 77, p. 1-24 24 p.

    Research output: Contribution to journal › Review › Research › peer-review

  30. Published

    Expression of endothelin type B receptors (EDNRB) on smooth muscle cells is controlled by ternary complex factors and the actin cytoskeleton

    Krawczyk, K. K., Skovsted, Gry Freja, Perisic, L., Rippe, C., Dreier, R., Berg, J. O., Lykkesfeldt, Jens, Hedin, U. & Sward, K., Apr 2018.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  31. Published

    Vasomotor function in rat arteries after ex vivo and intragastric exposure to food-grade titanium dioxide and vegetable carbon particles

    Jensen, Ditte Marie, Christophersen, D. V., Sheykhzade, Majid, Skovsted, Gry Freja, Lykkesfeldt, Jens, Münter, R., Roursgaard, Martin, Loft, Steffen & Møller, Peter, 26 Feb 2018, In: Particle and Fibre Toxicology. 15, p. 1-18 12.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Comparison of Three Sample Preparation Procedures for the Quantification of L-Arginine, Asymmetric Dimethylarginine, and Symmetric Dimethylarginine in Human Plasma Using HPLC-FLD

    Schou-Pedersen, A. M. V. & Lykkesfeldt, Jens, 1 Feb 2018, In: Journal of Analytical Methods in Chemistry. 2018, 7 p., 6148515.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Proximal Neuropathy and Associated Skeletal Muscle Changes Resembling Denervation Atrophy in Hindlimbs of Chronic Hypoglycaemic Rats

    Jensen, Vivi Flou Hjorth, Molck, A. M., Soeborg, H., Nowak, J., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., Jan 2018, In: Basic & Clinical Pharmacology & Toxicology. 122, 1, p. 165-175

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Basic & Clinical Pharmacology & Toxicology Policy for Experimental and Clinical studies

    Tveden-Nyborg, Pernille, Bergmann, T. K. & Lykkesfeldt, Jens, 2018, In: Basic & Clinical Pharmacology & Toxicology. 123, 3, p. 233-235 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  35. Published

    Biochemical and cognitive effects of docosahexaenoic acid differ in a developmental and SorLA dependent manner

    Højland, A., Richner, M., Mølgaard, S., Dieu, R. S., Eskelund, A., Nykjær, A., Nyengaard, J. R., Lykkesfeldt, Jens, Glerup, S. & Nielsen, M. S., 2018, In: Behavioural Brain Research. 348, p. 90-100 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Dietary fat stimulates development of NAFLD more potently than dietary fructose in Sprague-Dawley rats

    Jensen, Victoria Svop, Hvid, H., Damgaard, J., Nygaard, H., Ingvorsen, C., Wulff, E. M., Lykkesfeldt, Jens & Fledelius, C., 2018, In: Diabetology and Metabolic Syndrome. 10, 13 p., 4.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Early life vitamin C deficiency does not alter morphology of hippocampal CA1 pyramidal neurons or markers of synaptic plasticity in a Guinea pig model

    Hansen, S. N., Jørgensen, J. M. B., Nyengaard, J. R., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Nutrients. 10, 6, 749.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Factors Affecting the Absorption of Subcutaneously Administered Insulin: Effect on Variability

    Gradel, Anna Katrina Jógvansdóttir, Porsgaard, T., Lykkesfeldt, Jens, Seested, T., Gram-Nielsen, S., Kristensen, N. R. & Refsgaard, H., 2018, In: Journal of Diabetes Research. 2018, 17 p., 1205121.

    Research output: Contribution to journal › Review › Research › peer-review

  39. Published

    Heterozygous mutations in GTP-cyclohydrolase-1 reduce BH4 biosynthesis but not pain sensitivity

    Nasser, A., Møller, A. T., Hellmund, V., Thorborg, S. S., Jespersgaard, C., Bjerrum, Ole Jannik, Dupontd, E., Nachman, G., Lykkesfeldt, Jens, Jensen, T. S. & Møller, L. B., 2018, In: Pain. 159, 6, p. 1012-1024 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    High-fat feeding induces mobilization of vitamin C in obese prone rats

    Tranberg, B., Hellgren, L. I., Lykkesfeldt, Jens & Hansen, Axel Kornerup, 2018, In: Research in Veterinary Science. 119, p. 167-169 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Holder C-vitamin dine blodkar sunde?

    Skovsted, Gry Freja, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2018

    Research output: Other contribution › Net publication - Internet publication › Communication

  42. Published

    Liraglutide Decreases Hepatic Inflammation and Injury in Advanced Lean Non-Alcoholic Steatohepatitis

    Ipsen, David Højland, Rolin, B., Rakipovski, G., Skovsted, Gry Freja, Madsen, A., Kolstrup, S., Schou-Pedersen, A. M., Skat-Rørdam, Josephine, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Basic & Clinical Pharmacology & Toxicology. 123, 3, p. 704-713

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Long term Westernized diet leads to region-specific changes in brain signaling mechanisms

    Hansen, S. N., Ipsen, David Højland, Schou-Pedersen, A. M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Neuroscience Letters. 676, p. 85-91 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Long-term Western diet fed apolipoprotein E-deficient rats exhibit only modest early atherosclerotic characteristics

    Rune, Ida, Rolin, B., Lykkesfeldt, Jens, Nielsen, Dennis Sandris, Krych, Lukasz, Kanter, J. E., Bornfeldt, K. E., Kihl, Pernille, Buschard, K., Josefsen, K., Fels, J. J., Mortensen, A., Christoffersen, B., Kirk, R. K. & Hansen, Axel Kornerup, 2018, In: Scientific Reports. 8, 1, 12 p., 5416.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease

    Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Cellular and Molecular Life Sciences. 75, 18, p. 3313-3327 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  46. Published

    Pharmacological modulation of colorectal distension evoked potentials in conscious rats

    Nissen, T. D., Brock, C., Lykkesfeldt, Jens, Lindström, E. & Hultin, L., 2018, In: Neuropharmacology. 140, p. 193-200 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Spatial Memory Dysfunction Induced by Vitamin C Deficiency Is Associated with Changes in Monoaminergic Neurotransmitters and Aberrant Synapse Formation

    Hansen, S. N., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Antioxidants. 7, 7, p. 11 82.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Vasomotor dysfunction in human subcutaneous arteries exposed ex vivo to food-grade titanium dioxide

    Jensen, Ditte Marie, Skovsted, Gry Freja, Lykkesfeldt, Jens, Dreier, R., Berg, J. O., Jeppesen, J. L., Sheykhzade, Majid, Loft, Steffen & Møller, Peter, 2018, In: Food and Chemical Toxicology. 120, p. 321-327 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. 2017
  50. Published

    Clarithromycin, trimethoprim, and penicillin and oxidative nucleic acid modifications in humans: randomised, controlled trials

    Larsen, E. L., Cejvanovic, V., Kjær, L. K., Pedersen, M. T., Popik, S. D., Hansen, L. K., Andersen, Jon Thor Trærup, Solem, Espen Victor Jimenez, Broedbaek, K., Petersen, M., Weimann, A., Henriksen, T., Lykkesfeldt, Jens, Torp-Pedersen, C. & Poulsen, Henrik Enghusen, Aug 2017, In: British Journal of Clinical Pharmacology. 83, 8, p. 1643-1653

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Toxicological Effects during and following Persistent Insulin-Induced Hypoglycaemia in Healthy Euglycaemic Rats

    Jensen, Vivi Flou Hjorth, Molck, A., Berthelsen, L. O., Alifrangis, L., Andersen, L., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., Jul 2017, In: Basic & Clinical Pharmacology & Toxicology. 121, 1, p. 53-66

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Pasteurization Procedures for Donor Human Milk Affect Body Growth, Intestinal Structure, and Resistance against Bacterial Infections in Preterm Pigs

    Li, Y., Nguyen, Duc Ninh, de Waard, M., Christensen, Lars, Zhou, P., Jiang, Pingping, Sun, Jing, Bojesen, Anders Miki, Lauridsen, C., Lykkesfeldt, Jens, Dalsgaard, T. K., Bering, Stine Brandt & Sangild, Per Torp, Jun 2017, In: Journal of Nutrition. 147, 6, p. 1121-1130

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Endothelial dysfunction in the early postoperative period after major colon cancer surgery.

    Ekeløf, S., Larsen, M. H., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, Feb 2017, In: British Journal of Anaesthesia. 118, 2, p. 200-206

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Plasma lipid oxidation predicts atherosclerotic status better than cholesterol in diabetic apolipoprotein E deficient mice

    Petersen, Karen Ekkelund, Lykkesfeldt, Jens, Raun, K. & Rakipovski, G., Jan 2017, In: Experimental Biology and Medicine (Maywood). 242, 1, p. 88-91

    Research output: Contribution to journal › Journal article › Research › peer-review

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