Jesper Østergaard
Professor
Pharmaceutical Physical and Analytical Chemistry
Universitetsparken 2, 2100 København Ø
- 2023
- Published
Biorelevant Dissolution of Dipyridamole and Piroxicam Using an Automated UV/Vis Spectrophotometric and Potentiometric Dissolution Testing Platform
Berthelsen, R., Larsen, Susan Weng, Mullertz, Anette , Box, K. & Østergaard, Jesper, 2023, In: Dissolution Technologies. 30, 3, p. 144-153Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of UV-Vis Imaging Compatible Chromatographic Matrix with Application for Injectable Formulation Characterization
Bock, Frederik, Hu, A., Cicale, V., Larsen, Susan Weng, Lu, X. & Østergaard, Jesper, 2023, In: Analytical Chemistry. 95, 43, p. 15861–15866Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Numerical Mechanistic Modelling of Drug Release from Solvent-Removal Zein-Based In Situ Gel
Senarat, S., Pornsawad, P., Lertsuphotvanit, N., Østergaard, Jesper & Phaechamud, T., 2023, In: Pharmaceutics. 15, 10, 21 p., 2401.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Assessment of immunogenicity and drug activity in patient sera by flow-induced dispersion analysis
Pedersen, M. E., Østergaard, Jesper, Glintborg, Bente, Hetland, Merete Lund & Jensen, H., 2022, In: Scientific Reports. 12, 1, 10 p., 4670.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigation of diclofenac release and dynamic structural behavior of non-lamellar liquid crystal formulations during in situ formation by UV–Vis imaging and SAXS
Mertz, Nina, Bock, Frederik, Østergaard, Jesper, Yaghmur, Anan & Larsen, Susan Weng, 2022, In: International Journal of Pharmaceutics. 623, 121880.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Methodological Considerations in Development of UV Imaging for Characterization of Intra-Tumoral Injectables Using cAMP as a Model Substance
Bock, Frederik, Bøtker, Johan Peter, Larsen, Susan Weng, Lu, X. & Østergaard, Jesper, 2022, In: International Journal of Molecular Sciences. 23, 7, 18 p., 3599.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of Structural Integrity and Stability Using Nanograms of Protein by Flow-Induced Dispersion Analysis
Pedersen, M. E., Østergaard, Jesper & Jensen, H., 2022, In: Molecules. 27, 8, 8 p., 2506.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
An in vitro gel-based system for characterizing and predicting the long-term performance of PLGA in situ forming implants
Li, Z., Mu, Huiling, Larsen, Susan Weng, Jensen, H. & Østergaard, Jesper, 2021, In: International Journal of Pharmaceutics. 609, 12 p., 121183.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An investigation of drug compact topography as relates to intrinsic dissolution rates determined by dissolution imaging
Brown, B., Fazili, Z., Ward, A., Walton, K., Blunt, L., Østergaard, Jesper & Asare-Addo, K., 2021, In: Journal of Drug Delivery Science and Technology. 61, 10 p., 102143.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of selenium nanoparticles in human plasma by capillary electrophoresis hyphenated to inductively coupled plasma mass spectrometry
Gronbaek-Thorsen, F., Hansen, R. H., Østergaard, Jesper, Gammelgaard, Bente & Moller, L. H., 2021, In: Analytical and Bioanalytical Chemistry. 413, 8, p. 2247-2255Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Application of UV dissolution imaging to pharmaceutical systems
Brown, B., Ward, A., Fazili, Z., Østergaard, Jesper & Asare-Addo, K., 2021, In: Advanced Drug Delivery Reviews. 177, 26 p., 113949.Research output: Contribution to journal › Review › Research › peer-review
- Published
Comparison of external calibration and isotope dilution LC-ICP-MS/MS for quantitation of oxytocin and its selenium analogue in human plasma
Grønbæk-Thorsen, F., Jensen, C., Østergaard, Jesper, Møller, L. H. & Gammelgaard, Bente, 2021, In: Analytical and Bioanalytical Chemistry. 413, p. 6479–6488Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploration of in vitro drug release testing methods for saquinavir microenvironmental pH modifying buccal films
He, S., Jacobsen, Jette, Nielsen, C. U., Genina, Natalja, Østergaard, Jesper & Mu, Huiling, 2021, In: European Journal of Pharmaceutical Sciences. 163, 10 p., 105867.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Size-based characterization of adalimumab and TNF-alpha interactions using flow induced dispersion analysis: assessment of avidity-stabilized multiple bound species
Pedersen, M. E., Haegebaert, R. M. S., Østergaard, Jesper & Jensen, H., 2021, In: Scientific Reports. 11, 1, 10 p., 4754.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatially and time-resolved SAXS for monitoring dynamic structural transitions during in situ generation of non-lamellar liquid crystalline phases in biologically relevant media
Mertz, Nina, Yaghmur, Anan, Østergaard, Jesper, Amenitsch, H. & Larsen, Susan Weng, 2021, In: Journal of Colloid and Interface Science. 602, p. 415-425Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Towards functional characterization of excipients for oral solid dosage forms using UV-vis imaging. Liberation, release and dissolution
Li, Z., Sun, Y., Bar-Shalom, Daniel, Mu, Huiling, Larsen, Susan Weng, Jensen, H. & Østergaard, Jesper, 2021, In: Journal of Pharmaceutical and Biomedical Analysis. 194, 9 p., 113789.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
In-Solution IgG Titer Determination in Fermentation Broth Using Affibodies and Flow-Induced Dispersion Analysis
Pedersen, M. E., Østergaard, Jesper & Jensen, H., 28 Apr 2020, In: ACS Omega. 5, 18, p. 10519-10524 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An interlaboratory investigation of intrinsic dissolution rate determination using surface dissolution
Etherson, K., Dunn, C., Matthews, W., Pamelund, H., Barragat, C., Sanderson, N., Izumi, T., Mathews, C. D. C., Halbert, G., Wilson, C., McAllister, M., Mann, J., Østergaard, Jesper, Butler, J. & Khadra, I., 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 150, p. 24-32 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biopharmaceutical implications of excipient variability on drug dissolution from immediate release products
Zarmpi, P., Flanagan, T., Meehan, E., Mann, J., Østergaard, Jesper & Fotaki, N., 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 154, p. 195-209 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diclofenac prodrugs for intra-articular depot injectables: In vitro hydrolysis and species variation
Storgaard, Ida Klitzing, Kristensen, Jesper Langgaard, Larsen, C., Mertz, Nina, Østergaard, Jesper & Larsen, Susan Weng, 2020, In: Journal of Pharmaceutical Sciences. 109, 4, p. P1529-1536Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formulation of co-amorphous systems from naproxen and naproxen sodium and in situ monitoring of physicochemical state changes during dissolution testing by Raman spectroscopy
Ueda, H., Bøtker, Johan Peter, Edinger, M., Löbmann, Korbinian, Grohganz, Holger, Mullertz, Anette , Rades, Thomas & Østergaard, Jesper, 2020, In: International Journal of Pharmaceutics. 587, 119662.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Initial Leuprolide Acetate Release from Poly(D,L-lactide-co-glycolide) in Situ Forming Implants as Studied by Ultraviolet-Visible Imaging
Li, Z., Mu, Huiling, Larsen, Susan Weng, Jensen, H. & Østergaard, Jesper, 2020, In: Molecular Pharmaceutics. 17, 12, p. 4522-4532 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microenvironmental pH modifying films for buccal delivery of saquinavir: Effects of organic acids on pH and drug release in vitro
He, S., Østergaard, Jesper, Ashna, M., Nielsen, C. U., Jacobsen, Jette & Mu, Huiling, 2020, In: International Journal of Pharmaceutics. 585, 10 p., 119567.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Towards in vitro in vivo correlation for modified release subcutaneously administered insulins
Bock, Frederik, Lin, E., Larsen, C., Jensen, H., Huus, K., Larsen, Susan Weng & Østergaard, Jesper, 2020, In: European Journal of Pharmaceutical Sciences. 145, 10 p., 105239.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Transport characteristics in a novel in vitro release model for testing the performance of intra-articular injectables
Mertz, Nina, Østergaard, Jesper, Yaghmur, Anan & Larsen, Susan Weng, 20 Jul 2019, In: International Journal of Pharmaceutics. 566, p. 445-453Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein Characterization in 3D: Size, Folding and Functional Assessment in a Unified Approach
Pedersen, M. E., Gad, S. I., Østergaard, Jesper & Jensen, H., 27 Mar 2019, In: Analytical Chemistry. 91, 8, p. 4975-4979Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Flow-Induced Dispersion Analysis (FIDA) for Protein Quantification and Characterization
Pedersen, M. E., Østergaard, Jesper & Jensen, H., 2019, Clinical Applications of Capillary Electrophoresis. Springer, Vol. 1972. p. 109-123 15 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Monitoring of antimicrobial drug chloramphenicol release from electrospun nano-and microfiber mats using UV imaging and bacterial bioreporters
Preem, L., Bock, Frederik, Hinnu, M., Putrinš, M., Sagor, K., Tenson, T., Meos, A., Østergaard, Jesper & Kogermann, K., 2019, In: Pharmaceutics. 11, 9, 19 p., 487.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simulated synovial fluids for in vitro drug and prodrug release testing of depot injectables intended for joint injection
Thing, M., Mertz, Nina, Ågårdh, L., Larsen, Susan Weng, Østergaard, Jesper & Larsen, C., 2019, In: Journal of Drug Delivery Science and Technology. 49, p. 169-176 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Cisplatin Encapsulation Generates Morphologically Different Multicompartments in the Internal Nanostructures of Nonlamellar Liquid-Crystalline Self-Assemblies
Azmi, I. D. M., Østergaard, Jesper, Stürup, Stefan, Gammelgaard, Bente, Urtti, A., Moghimi, S. M. & Yaghmur, Anan, 5 Jun 2018, In: Langmuir : the ACS journal of surfaces and colloids. 34, 22, p. 6570-6581 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
UV-vis Imaging of Piroxicam Supersaturation, Precipitation, and Dissolution in a Flow-Through Setup
Sun, Y., Chapman, A., Larsen, Susan Weng, Jensen, H., Petersen, Nickolaj J., Goodall, D. M. & Østergaard, Jesper, 5 Jun 2018, In: Analytical Chemistry. 90, 11, p. 6413-6418Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Manipulating Aggregation Behavior of the Uncharged Peptide Carbetocin
Høgstedt, U. B., Østergaard, Jesper, Weiss, T., Sjögren, H. & van de Weert, Marco, Mar 2018, In: Journal of Pharmaceutical Sciences. 107, 3, p. 838-847 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
UV imaging in pharmaceutical analysis
Østergaard, Jesper, 5 Jan 2018, In: Journal of Pharmaceutical and Biomedical Analysis. 147, p. 140-148Research output: Contribution to journal › Review › Research › peer-review
- Published
Concomitant monitoring of implant formation and drug release of in situ forming poly (lactide-co-glycolide acid) implants in a hydrogel matrix mimicking the subcutis using UV–vis imaging
Sun, Y., Jensen, H., Petersen, Nickolaj J., Larsen, Susan Weng & Østergaard, Jesper, 2018, In: Journal of Pharmaceutical and Biomedical Analysis. 150, p. 95-106Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Phase separation of in situ forming poly (lactide-co-glycolide acid) implants investigated using a hydrogel-based subcutaneous tissue surrogate and UV-vis imaging
Sun, Y., Jensen, H., Petersen, Nickolaj J., Larsen, Susan Weng & Østergaard, Jesper, 25 Oct 2017, In: Journal of Pharmaceutical and Biomedical Analysis. 145, p. 682-691 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variable-focus microscopy and UV surface dissolution imaging as complementary techniques in intrinsic dissolution rate determination
Ward, A., Walton, K., Box, K., Østergaard, Jesper, Gillie, L. J., Conway, B. R. & Asare-Addo, K., 15 Sep 2017, In: International Journal of Pharmaceutics. 530, 1-2, p. 139-144 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissolution enhancement of griseofulvin from griseofulvin-sodium dodecyl sulfate discs investigated by UV imaging
Madelung, P., Bertelsen, P., Jacobsen, Jette, Mullertz, Anette & Østergaard, Jesper, Jun 2017, In: Journal of Drug Delivery Science and Technology. 39, p. 516-522 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Automated coating procedures to produce poly(ethylene glycol) brushes in fused-silica capillaries
Poulsen, N. N., Østergaard, Jesper, Petersen, Nickolaj J., Daasbjerg, K., Iruthayaraj, J., Dedinaite, A., Makuska, R. & Jensen, H., Feb 2017, In: Journal of Separation Science. 40, 3, p. 779–788Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Application of UV Imaging in Formulation Development
Sun, Y. & Østergaard, Jesper, 2017, In: Pharmaceutical Research. 34, 5, p. 929–940 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Limits in Size of Taylor Dispersion Analysis: Representation of the Different Hydrodynamic Regimes and Application to the Size-Characterization of Cubosomes
Chamieh, J., Leclercq, L., Martin, M., Slaoui, S., Jensen, H., Østergaard, Jesper & Cottet, H., 2017, In: Analytical Chemistry. 89, 24, p. 13487-13493Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Performance characteristics of UV imaging instrumentation for diffusion, dissolution and release testing studies
Jensen, S. S., Jensen, H., Goodall, D. M. & Østergaard, Jesper, 30 Nov 2016, In: Journal of Pharmaceutical and Biomedical Analysis. 131, p. 113-123 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-Acting Diclofenac Ester Prodrugs for Joint Injection: Kinetics, Mechanism of Degradation, and In Vitro Release From Prodrug Suspension
Mertz, Nina, Larsen, Susan Weng, Kristensen, Jesper Langgaard, Østergaard, Jesper & Larsen, C., 27 Jul 2016, In: Journal of Pharmaceutical Sciences. 105, 10, p. 3079–3087 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Taylor Dispersion Analysis as a promising tool for assessment of peptide-peptide interactions
Høgstedt, U. B., Schwach, G., van de Weert, Marco & Østergaard, Jesper, 25 Jul 2016, In: European Journal of Pharmaceutical Sciences. 93, p. 21-28 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IMIDAZOLE DERIVATIVES AS PRODRUGS OF DICLOFENAC
Larsen, C. S., Larsen, Susan Weng, Thing, M. A., Kristensen, Jesper Langgaard, JENSEN, H. & Østergaard, Jesper, 6 May 2016, IPC No. A61P 29/ 00 A I, Patent No. WO2016066612, Priority date 28 Oct 2014, Priority No. DK20140070657Research output: Patent
- Published
PRODRUGS OF NAPROXEN AND DICLOFENAC
Larsen, C. S., Larsen, Susan Weng, Thing, M. A., Kristensen, Jesper Langgaard, JENSEN, H. & Østergaard, Jesper, 17 Mar 2016, IPC No. A61K 45/ 06 A I, Patent No. US2016074523, Priority date 28 Apr 2014, Priority No. WO2014EP58530Research output: Patent
- Published
Role of Electrostatic Interactions on the Transport of Druglike Molecules in Hydrogel-Based Articular Cartilage Mimics: Implications for Drug Delivery
Ye, F., Baldursdottir, S., Hvidt, S., Jensen, H., Larsen, Susan Weng, Yaghmur, Anan, Larsen, C. & Østergaard, Jesper, 7 Mar 2016, In: Molecular Pharmaceutics. 13, 3, p. 819-28 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro release studies of insulin from lipid implants in solution and in a hydrogel matrix mimicking the subcutis
Jensen, S. S., Jensen, H., Møller, E. H., Cornett, Claus, Siepmann, F., Siepmann, J. & Østergaard, Jesper, 1 Jan 2016, In: European Journal of Pharmaceutical Sciences. 81, p. 103-12 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Flow-Induced Dispersion Analysis for Probing Anti-dsDNA Antibody Binding Heterogeneity in Systemic Lupus Erythematosus Patients: Toward a New Approach for Diagnosis and Patient Stratification
Poulsen, N. N., Pedersen, M. E., Østergaard, Jesper, Petersen, Nickolaj J., Nielsen, C. T., Heegaard, N. H. H. & Jensen, H., 2016, In: Analytical Chemistry. 88, 18, p. 9056-61 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of pharmaceutical peptides in human plasma by LC-ICP-MS sulfur detection
Møller, L. H., Macherius, A., Hansen, Thomas Hesselhøj, Nielsen, Hanne Mørck, Cornett, Claus, Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 2016, In: Journal of Analytical Atomic Spectrometry. 31, p. 1877-1884 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Matrix effects in nilotinib formulations with pH-responsive polymer produced by carbon dioxide-mediated precipitation
Colombo, S., Brisander, M., Haglöf, J., Sjövall, P., Andersson, P., Østergaard, Jesper & Malmsten, M., 15 Oct 2015, In: International Journal of Pharmaceutics. 494, 1, p. 205-217 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1299275
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Quantification of pharmaceutical peptides in human plasma by LC-ICP-MS sulfur detection
Research output: Contribution to journal › Journal article › Research › peer-review
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Application of UV Imaging in Formulation Development
Research output: Contribution to journal › Journal article › Research › peer-review
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Performance characteristics of UV imaging instrumentation for diffusion, dissolution and release testing studies
Research output: Contribution to journal › Journal article › Research › peer-review
Published