Jesper Langgaard Kristensen
Jesper Langgaard Kristensen

Professor with special responsibilities

Primary fields of research

Research interests

Generally medicinal chemistry and the development of new methodology for the construction of compound classes of relevance to medicinal chemistry. Using these tools we are trying to develop new probes and tools that will help us to elucidate the underlying mechanisms responsible for the regulation of different pharmacological targets: Ion channels, enzymes and GPCR’s.

Please see group web-page for more informantion.

 - Member of the Horizon2020 “Click-It” consortium receiving 6 mio. Euro (2015-2020) where we are developing a new imaging technology based on in-vivo click-chemistry.

 - Member of the Marie Curie ETN "AlphaSy" consortium receiving 4.1 mio. Euro (2018-2022) where we are developing a new imaging agents to diagnose Parkisons disease at an early stage.

 - Coordinator of the ETN-EID project SAFER receiving 1.3 mio. Euro (2017-2021). SAFER aims to identify functionally Selective Agonists for the 5-HT2A Serotonin Receptor.

Possible conflicts of interest

Founder and CSO @ Lophora (www.lophora.com)

Selected publications

  1. E-pub ahead of print

    Dark Classics in Chemical Neuroscience: NBOMes

    Poulie, Christian Bernard Matthijs, Jensen, Anders A., Halberstadt, A. & Kristensen, Jesper Langgaard, 28 Oct 2019, In : ACS Chemical Neuroscience.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Enantioselective Total Synthesis of (+)-Dihydro-β-erythroidine

    Clementson, S., Jessing, M., Pedersen, H., Vital, P. & Kristensen, Jesper Langgaard, May 2019, In : Journal of the American Chemical Society. 141, 22, p. 8783-8786

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Detailed characterization of the in vitro pharmacological and pharmacokinetic properties of N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine (25CN-NBOH), a highly selective and brain-penetrant 5-HT2A receptor agonist

    Jensen, Anders A., McCorvy, J. D., Petersen, S. L., Bundgaard, C., Liebscher, G., Kenakin, T. P., Bräuner-Osborne, Hans, Kehler, J. & Kristensen, Jesper Langgaard, 2017, In : Journal of Pharmacology and Experimental Therapeutics. 361, 3, p. 441-453

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    In situ generation of the Ohira-Bestmann Reagent from stable sulfonyl azide: scalable synthesis of alkynes from aldehydes

    Jepsen, T. H. & Kristensen, Jesper Langgaard, 12 Sep 2014, In : Journal of Organic Chemistry. 79, 19, p. 9423-9426 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 1305029