Jesper Østergaard
Professor
Pharmaceutical Physical and Analytical Chemistry
Universitetsparken 2, 2100 København Ø
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Behaviour of HPMC compacts investigated using UV-imaging
Pekka Pajander, J., Baldursdottir, S. G., Rantanen, Jukka & Østergaard, Jesper, 2012, In: International Journal of Pharmaceutics. 427, 2, p. 345-353Research output: Contribution to journal › Journal article › Research › peer-review
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Protein Characterization in 3D: Size, Folding and Functional Assessment in a Unified Approach
Pedersen, M. E., Gad, S. I., Østergaard, Jesper & Jensen, H., 27 Mar 2019, In: Analytical Chemistry. 91, 8, p. 4975-4979Research output: Contribution to journal › Journal article › Research › peer-review
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In-Solution IgG Titer Determination in Fermentation Broth Using Affibodies and Flow-Induced Dispersion Analysis
Pedersen, M. E., Østergaard, Jesper & Jensen, H., 28 Apr 2020, In: ACS Omega. 5, 18, p. 10519-10524 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Size-based characterization of adalimumab and TNF-alpha interactions using flow induced dispersion analysis: assessment of avidity-stabilized multiple bound species
Pedersen, M. E., Haegebaert, R. M. S., Østergaard, Jesper & Jensen, H., 2021, In: Scientific Reports. 11, 1, 10 p., 4754.Research output: Contribution to journal › Journal article › Research › peer-review
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Quantification of Structural Integrity and Stability Using Nanograms of Protein by Flow-Induced Dispersion Analysis
Pedersen, M. E., Østergaard, Jesper & Jensen, H., 2022, In: Molecules. 27, 8, 8 p., 2506.Research output: Contribution to journal › Journal article › Research › peer-review
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Assessment of immunogenicity and drug activity in patient sera by flow-induced dispersion analysis
Pedersen, M. E., Østergaard, Jesper, Glintborg, Bente, Hetland, Merete Lund & Jensen, H., 2022, In: Scientific Reports. 12, 1, 10 p., 4670.Research output: Contribution to journal › Journal article › Research › peer-review
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Flow-Induced Dispersion Analysis (FIDA) for Protein Quantification and Characterization
Pedersen, M. E., Østergaard, Jesper & Jensen, H., 2019, Clinical Applications of Capillary Electrophoresis. Springer, Vol. 1972. p. 109-123 15 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Cu(II) mediates kineticallyl distinct, non-amyloidogenic aggregation of amyloid-β peptides
Pedersen, J. T., Østergaard, Jesper, Rozlosnik, N., Gammelgaard, Bente & Heegaard, N. H. H., 2011, In: Journal of Biological Chemistry. 286, 30, p. 26952-26963Research output: Contribution to journal › Journal article › Research › peer-review
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Rapid exchange of metal between Zn7-metallothionein-3 and amyloid-β peptide promotes amyloid-related structural changes
Pedersen, J. T., Hureau, C., Hemmingsen, Lars Bo Stegeager, Heegaard, N. H. H., Østergaard, Jesper, Vasák, M. & Faller, P., 2012, In: Biochemistry. 51, 8, p. 1697-1706Research output: Contribution to journal › Journal article › Research › peer-review
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Affinity capillary electrophoresis for identification and investigation of human Gc-globulin (vitamin D-binding protein) and its isoforms interacting with G-actin
Pedersen, J. T., Østergaard, Jesper, Houen, G. & Heegaard, N. H. H., 2008, In: Electrophoresis. 29, 8, p. 1723-1733Research output: Contribution to journal › Journal article › Research › peer-review
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Rapid formation of a preoligomeric peptide-metal-peptide complex following copper(II) binding to amyloid β peptides
Pedersen, J. T., Teilum, Kaare, Heegaard, N. H. H., Østergaard, Jesper, Adolph, H. & Hemmingsen, Lars Bo Stegeager, 2011, In: Angewandte Chemie International Edition. 50, 11, p. 2532-2535 4 p.Research output: Contribution to journal › Letter › Research › peer-review
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Physicochemical characteristics and in vitro release from oil-based vehicles of peptidomimetics: parenteral depots for intra-articular administration
Pedersen, B. T., Østergaard, Jesper, Larsen, Susan Weng, Cornett, Claus, Ankersen, M. & Larsen, C. S., 2011, In: Drug Development and Industrial Pharmacy. 37, 1, p. 62-71Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro assessment of lidocaine release from aqueous and oil solutions and from preformed and in situ formed aqueos and oil suspensions. Parenteral depots for intra-articular administration
Pedersen, B. T., Larsen, Susan Weng, Østergaard, Jesper & Larsen, C. S., 2008, In: Drug Delivery. 15, 1, p. 23-30Research output: Contribution to journal › Journal article › Research › peer-review
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Simultaneous UV Imaging and Raman Spectroscopy for the Measurement of Solvent-Mediated Phase Transformations During Dissolution Testing
Østergaard, Jesper, Wu, J., Naelapää, K., Bøtker, Johan Peter, Jensen, H. & Rantanen, Jukka, Apr 2014, In: Journal of Pharmaceutical Sciences. 103, 4, p. 1149-56 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Microenvironmental pH measurement during sodium naproxenate dissolution in acidic medium by UV/vis imaging
Østergaard, Jesper, Jensen, H., Larsen, Susan Weng, Larsen, C. & Lenke, J., 17 Aug 2014, In: Journal of Pharmaceutical and Biomedical Analysis. 100, p. 290-293 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Monitoring Lidocaine Single-Crystal Dissolution by Ultraviolet Imaging
Østergaard, Jesper, Ye, F., Rantanen, Jukka, Yaghmur, Anan, Larsen, Susan Weng, Larsen, C. S. & Jensen, H., Aug 2011, In: Journal of Pharmaceutical Sciences. 100, 8, p. 3405-3410Research output: Contribution to journal › Journal article › Research › peer-review
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SPECT/CT imaging of radiolabeled cubosomes and hexosomes for potential theranostic applications
Nilsson, C., Barrios-Lopez, B., Kallinen, A., Laurinmäki, P., Butcher, S. J., Raki, M., Weisell, J., Bergström, K., Larsen, Susan Weng, Østergaard, Jesper, Larsen, C., Urtti, A., Airaksinen, A. J. & Yaghmur, Anan, 7 Aug 2013, In: Biomaterials. 34, 33, p. 8491-8503Research output: Contribution to journal › Journal article › Research › peer-review
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PEGylation of Phytantriol-Based Lyotropic Liquid Crystalline Particles-The Effect of Lipid Composition, PEG Chain Length, and Temperature on the Internal Nanostructure
Nilsson, C., Østergaard, Jesper, Larsen, Susan Weng, Larsen, C., Urtti, A. & Yaghmur, Anan, 10 Jun 2014, In: Langmuir : the ACS journal of surfaces and colloids. 30, 22, p. 6398-6407 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of oil-free and oil-loaded liquid-crystalline particles stabilized by negatively charged stabilizer citrem
Nilsson, C., Edwards, K., Eriksson, J., Larsen, Susan Weng, Østergaard, Jesper, Larsen, C. S., Urtti, A. & Yaghmur, Anan, 2012, In: Langmuir. 28, 32, p. 11755-11766Research output: Contribution to journal › Journal article › Research › peer-review
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Biorelevant characterisation of amorphous furosemide salt exhibits conversion to a furosemide hydrate during dissolution
Nielsen, L. H., Gordon, S., Pajander, J. P., Østergaard, Jesper, Rades, Thomas & Mullertz, Anette , 30 Nov 2013, In: International Journal of Pharmaceutics. 457, 1, p. 14-24 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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pH-triggered drug release from biodegradable microwells for oral drug delivery
Nielsen, L. H., Nagstrup, J., Gordon, S., Keller, S. S., Østergaard, Jesper, Rades, Thomas, Mullertz, Anette & Boisen, A., Jun 2015, In: Biomedical Microdevices. 17, 7 p., 55.Research output: Contribution to journal › Journal article › Research › peer-review
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Simultaneous measurement of phosphorus and platinum by size exclusion chromatography coupled to inductively coupled plasma mass spectrometry (SEC-ICPMS) using xenon as reactive collision gas for charaterization of platinum drug liposomes
Nguyen, T. T. N. T., Stürup, Stefan, Østergaard, Jesper, Franzen, U. & Gammelgaard, Bente, 2011, In: Journal of Analytical Atomic Spectrometry. 26, 7, p. 1466-1473Research output: Contribution to journal › Journal article › Research › peer-review
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Determination of platinum drug release and liposome stability in human plasma by CE-ICP-MS
Nguyen, T. T. N. T., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 5 Jun 2013, In: International Journal of Pharmaceutics. 449, 1-2, p. 95-102 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Metallomics in drug development: characterization of a liposomal cisplatin drug formulation in human plasma by CE-ICP-MS
Nguyen, T. T. N. T., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 2013, In: Analytical and Bioanalytical Chemistry. 405, 6, p. 1845-1854Research output: Contribution to journal › Journal article › Research › peer-review
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Investigation of a liposomal oxaliplatin drug formulation by capillary electrophoresis hyphenated to inductively coupled plasma mass spectrometry (CE-ICP-MS)
Nguyen, T. T. N. T., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 2012, In: Analytical and Bioanalytical Chemistry. 402, p. 2131-2139Research output: Contribution to journal › Journal article › Research › peer-review
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Kvalitetssikring af målrettede nanopartikler til kemoterapi
Nguyen, T. T. N. T., Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 2013, In: Lægemiddelforskning. 2012, p. 50-51Research output: Contribution to journal › Journal article › Communication
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A method for studies on interactions between a gold-based drug and plasma proteins based on capillary electrophoresis with inductively coupled plasma mass spectrometry detection
Nguyen, T. T. T. N., Østergaard, Jesper & Gammelgaard, Bente, 2 Sep 2015, In: Analytical and Bioanalytical Chemistry. 407, 28, p. 8497-8503 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Quantification of pharmaceutical peptides in human plasma by LC-ICP-MS sulfur detection
Møller, L. H., Macherius, A., Hansen, Thomas Hesselhøj, Nielsen, Hanne Mørck, Cornett, Claus, Østergaard, Jesper, Stürup, Stefan & Gammelgaard, Bente, 2016, In: Journal of Analytical Atomic Spectrometry. 31, p. 1877-1884 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Stability, liposome interaction, and in vivo pharmacology of ghrelin in liposomal suspensions
Møller, E. H., Holst, Birgitte, Nielsen, L. H., Pedersen, P. S. & Østergaard, Jesper, 2010, In: Internation Journal of Pharmaceutics. 390, 1, p. 13-18Research output: Contribution to journal › Journal article › Research › peer-review
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Development and validation of a microemulsion electrokinetic chromatography method for patulin quantification in commercial apple juice
Murillo-Arbizu, M., González-Peñas, E., Hansen, S. H., Amézqueta, S. & Østergaard, Jesper, 2008, In: Food and Chemical Toxicology. 46, 6, p. 2251-2257Research output: Contribution to journal › Journal article › Research › peer-review
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Long-Acting Diclofenac Ester Prodrugs for Joint Injection: Kinetics, Mechanism of Degradation, and In Vitro Release From Prodrug Suspension
Mertz, Nina, Larsen, Susan Weng, Kristensen, Jesper Langgaard, Østergaard, Jesper & Larsen, C., 27 Jul 2016, In: Journal of Pharmaceutical Sciences. 105, 10, p. 3079–3087 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Spatially and time-resolved SAXS for monitoring dynamic structural transitions during in situ generation of non-lamellar liquid crystalline phases in biologically relevant media
Mertz, Nina, Yaghmur, Anan, Østergaard, Jesper, Amenitsch, H. & Larsen, Susan Weng, 2021, In: Journal of Colloid and Interface Science. 602, p. 415-425Research output: Contribution to journal › Journal article › Research › peer-review
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Investigation of diclofenac release and dynamic structural behavior of non-lamellar liquid crystal formulations during in situ formation by UV–Vis imaging and SAXS
Mertz, Nina, Bock, Frederik, Østergaard, Jesper, Yaghmur, Anan & Larsen, Susan Weng, 2022, In: International Journal of Pharmaceutics. 623, 121880.Research output: Contribution to journal › Journal article › Research › peer-review
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Transport characteristics in a novel in vitro release model for testing the performance of intra-articular injectables
Mertz, Nina, Østergaard, Jesper, Yaghmur, Anan & Larsen, Susan Weng, 20 Jul 2019, In: International Journal of Pharmaceutics. 566, p. 445-453Research output: Contribution to journal › Journal article › Research › peer-review
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Modulatory Effect of Human Plasma on the Internal Nanostructure and Size Characteristics of Liquid-Crystalline Nanocarriers
Mat Azmi, I. D. B., Wu, L., Wibroe, P. P., Nilsson, C., Østergaard, Jesper, Stürup, Stefan, Gammelgaard, Bente, Urtti, A., Moghimi, S. M. & Yaghmur, Anan, 30 Apr 2015, In: Langmuir. 31, 18, p. 5042–49 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dissolution enhancement of griseofulvin from griseofulvin-sodium dodecyl sulfate discs investigated by UV imaging
Madelung, P., Bertelsen, P., Jacobsen, Jette, Mullertz, Anette & Østergaard, Jesper, Jun 2017, In: Journal of Drug Delivery Science and Technology. 39, p. 516-522 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of sodium dodecyl sulphate on the dissolution of poorly soluble drug into biorelevant medium from drug-surfactant discs
Madelung, P., Østergaard, Jesper, Bertelsen, P., Jørgensen, E. V., Jacobsen, Jette & Mullertz, Anette , 2 Mar 2014, In: International Journal of Pharmaceutics. 467, 1-2, p. 1-8Research output: Contribution to journal › Journal article › Research › peer-review
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Initial Leuprolide Acetate Release from Poly(D,L-lactide-co-glycolide) in Situ Forming Implants as Studied by Ultraviolet-Visible Imaging
Li, Z., Mu, Huiling, Larsen, Susan Weng, Jensen, H. & Østergaard, Jesper, 2020, In: Molecular Pharmaceutics. 17, 12, p. 4522-4532 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Towards functional characterization of excipients for oral solid dosage forms using UV-vis imaging. Liberation, release and dissolution
Li, Z., Sun, Y., Bar-Shalom, Daniel, Mu, Huiling, Larsen, Susan Weng, Jensen, H. & Østergaard, Jesper, 2021, In: Journal of Pharmaceutical and Biomedical Analysis. 194, 9 p., 113789.Research output: Contribution to journal › Journal article › Research › peer-review
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An in vitro gel-based system for characterizing and predicting the long-term performance of PLGA in situ forming implants
Li, Z., Mu, Huiling, Larsen, Susan Weng, Jensen, H. & Østergaard, Jesper, 2021, In: International Journal of Pharmaceutics. 609, 12 p., 121183.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro and in vivo characteristics of celecoxib in situ formed suspensions for intra-articular administration
Larsen, Susan Weng, Frost, A. B., Østergaard, Jesper, Thomsen, M. H., Jacobsen, Stine, Skonberg, C., Hansen, S. H., Jensen, Henrik Elvang & Larsen, C. S., 2011, In: Journal of Pharmaceutical Sciences. 100, 10, p. 4330-4337 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Assessment of drug release from oil depot formulations using an in vitro model: Potential applicability in accelerated release testing
Larsen, Susan Weng, Jessen, M. N. B., Østergaard, Jesper & Larsen, C. S., 2008, In: Drug Development and Industrial Pharmacy. 34, 3, p. 297-304Research output: Contribution to journal › Journal article › Research › peer-review
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On the mechanism of drug release from oil suspensions in vitro using local anasthetics as model drug compounds
Larsen, Susan Weng, Frost, A. B., Østergaard, Jesper, Marcher, H. & Larsen, C. S., 2008, In: European Journal of Pharmaceutical Sciences. 34, 1, p. 37-44Research output: Contribution to journal › Journal article › Research › peer-review
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Use of in vitro release models in the design of sustained and localized drug delivery systems for subcutaneous and intra-articular administration
Larsen, Susan Weng, Østergaard, Jesper, Yaghmur, Anan, Jensen, H. & Larsen, C., 2013, In: Journal of Drug Delivery Science and Technology. 23, p. 333-345Research output: Contribution to journal › Journal article › Research › peer-review
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Diflunisal salts of bupivacaine, lidocaine and morphine. Use of the common ion effect for prolonging the release of bupivacaine from mixed salt suspensions in an in vitro dialysis model
Larsen, Susan Weng, Østergaard, Jesper, Poulsen, S., Schulz, B. & Larsen, C. S., 2007, In: European Journal of Pharmaceutical Sciences. 31, 3-4, p. 172-179Research output: Contribution to journal › Journal article › Research › peer-review
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In situ formed suspensions for local sustained action of celecoxib following intra-articular administration
Larsen, Susan Weng, Frost, A. B., Østergaard, Jesper, Jacobsen, Stine, Thomsen, M. H., Lindegaard, Casper, Andersen, P. H. & Larsen, C. S., 2009. 2 p.Research output: Contribution to conference › Poster › Research
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Medicindepot dannes efter injektion i leddet
Larsen, Susan Weng, Thing, M. A., Østergaard, Jesper, Kristensen, Jesper Langgaard, Hansen, M. & Larsen, C. S., 2013, In: Lægemiddelforskning. 2013, p. 38-40Research output: Contribution to journal › Journal article › Research
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IMIDAZOLE DERIVATIVES AS PRODRUGS OF DICLOFENAC
Larsen, C. S., Larsen, Susan Weng, Thing, M. A., Kristensen, Jesper Langgaard, JENSEN, H. & Østergaard, Jesper, 6 May 2016, IPC No. A61P 29/ 00 A I, Patent No. WO2016066612, Priority date 28 Oct 2014, Priority No. DK20140070657Research output: Patent
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PRODRUGS OF NAPROXEN AND DICLOFENAC
Larsen, C. S., Larsen, Susan Weng, Thing, M. A., Kristensen, Jesper Langgaard, JENSEN, H. & Østergaard, Jesper, 17 Mar 2016, IPC No. A61K 45/ 06 A I, Patent No. US2016074523, Priority date 28 Apr 2014, Priority No. WO2014EP58530Research output: Patent
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Role of in vitro release models in formulation development and quality control of parenteral depots
Larsen, C. S., Larsen, Susan Weng, Jensen, H., Yaghmur, Anan & Østergaard, Jesper, 2009, In: Expert Opinion on Drug Delivery. 6, 12, p. 1283-1295Research output: Contribution to journal › Review › Research
ID: 1299275
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Quantification of pharmaceutical peptides in human plasma by LC-ICP-MS sulfur detection
Research output: Contribution to journal › Journal article › Research › peer-review
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Application of UV Imaging in Formulation Development
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Performance characteristics of UV imaging instrumentation for diffusion, dissolution and release testing studies
Research output: Contribution to journal › Journal article › Research › peer-review
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