Alicia Lundby
Affiliated Associate Professor, Professor with special responsibilities, Professor MSO
Mann Group
Blegdamsvej 3B
2200 København N
Molecular Cardiology and Membrane Proteins
Blegdamsvej 3, 2200 København N.
Member of:
- Published
KCNQ1 mutation Q147R is associated with atrial fibrillation and prolonged QT interval.
Lundby, Alicia, Ravn, L. S., Svendsen, Jesper Hastrup, Olesen, Søren-Peter & Schmitt, Nicole, 2007, In: Heart Rhythm. 4, 12, p. 1532-41 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KIT(D816V) Induces SRC-Mediated Tyrosine Phosphorylation of MITF and Altered Transcription Program in Melanoma
Phung, B., Kazi, J. U., Lundby, Alicia, Bergsteinsdottir, K., Sun, J., Goding, C. R., Jönsson, G., Olsen, Jesper Velgaard, Steingrímsson, E. & Rönnstrand, L., 2017, In: Molecular cancer research : MCR. 15, 9, p. 1265-1274 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of Nuclear Envelope Integrity and Increased Oxidant Production Cause DNA Damage in Adult Hearts Deficient in PKP2: A Molecular Substrate of ARVC
Perez-Hernandez, M., van Opbergen, C. J. M., Bagwan, N., Vissing, C. R., Marron-Linares, G. M., Zhang, M., Vega, E. T., Sorrentino, A., Drici, L., Sulek, K., Zhai, R., Hansen, F. B., Christensen, A. H., Boesgaard, S., Gustafsson, F., Rossing, K., Small, E. M., Davies, M. J., Rothenberg, E., Sato, P. Y. & 6 others, , 2022, In: Circulation. 146, 11, p. 851-867Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular switches in signaling networks as a mechanism of action for oncogenic mutations in proximity of tyrosine residues
Emdal, Kristina Bennet & Lundby, Alicia, 2020, In: Molecular & Cellular Oncology. 7, 1, 3 p., e1692643.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Molecular template for a voltage sensor in a novel K+ channel I. Identification and functional characterization of KvLm, a voltage-gated K+ channel form Listeria monocytogenes
Santos, J., Lundby, Alicia, Zazueta, C. & Montal, M., 2006, In: Journal of General Physiology. 128 (3), p. 283-292Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular template for a voltage sensor in a novel K+ channel II. Conservation of a eukaryotic sensor fold in a prokaryotic K+ channel
Lundby, Alicia, Santos, J., Zazueta, C. & Montal, M., 2006, In: Journal of General Physiology. 128 (3), p. 293-300Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
Lundby, Alicia, Franciosa, Giulia, Emdal, Kristina Bennet, Refsgaard, J. C., Gnosa, S. P., Bekker-Jensen, D. B., Secher, A., Maurya, S. R., Paul, I., Mendez, B. L., Kelstrup, C. D., Francavilla, C., Kveiborg, Marie, Montoya, Guillermo, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2019, In: Cell. 179, 2, p. 543-560Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oncotherapeutic Protein Kinase Inhibitors Associated With Pro-Arrhythmic Liability
Ye, J. Z., Hansen, F. B., Mills, Robert William & Lundby, Alicia, 2021, In: JACC: CardioOncology. 3, 1, p. 88-97Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Outlining cardiac ion channel protein interactors and their signature in the human electrocardiogram
Maurya, S., Mills, Robert William, Kahnert, Konstantin, Chiang, D. Y., Bertoli, G., Lundegaard, Pia Rengtved, Duran, M. P. H., Zhang, M., Rothenberg, E., George, A. L., MacRae, C. A., Delmar, M. & Lundby, Alicia, 2023, In: Nature Cardiovascular Research. 2, 7, p. 673-692 38 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PKD Phosphorylation as Novel Pathway of KV11.1 Regulation
Steffensen, Annette Buur, Bomholtz, Sofia Hammami, Andersen, M. N., Olsen, Jesper Velgaard, Mutsaers, N., Lundegaard, Pia Rengtved, Lundby, Alicia & Schmitt, Nicole, 2018, In: Cellular Physiology and Biochemistry. 47, 4, p. 1742-1750 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phosphoproteomics taken to heart
Lundby, Alicia & Olsen, Jesper Velgaard, 1 Sep 2013, In: Cell Cycle. 12, 17, p. 2707-2708 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Protein kinase A stimulates Kv7.1 surface expression by regulating Nedd4-2-dependent endocytic trafficking
Andersen, M. N., Hefting, L. L., Steffensen, Annette Buur, Schmitt, Nicole, Olesen, Søren-Peter, Olsen, Jesper Velgaard, Lundby, Alicia & Rasmussen, Hanne Borger, 15 Nov 2015, In: American Journal of Physiology: Cell Physiology. 309, 10, p. C693-C706 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteome-wide profiling and mapping of post translational modifications in human hearts
Bagwan, N., El Ali, Henrik H. & Lundby, Alicia, 2021, In: Scientific Reports. 11, 1, 10 p., 2184.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns
Lundby, Alicia, Hansen, K. L., Weinert, B. T., Breinholt Bekker-Jensen, D., Secher, A., Skovgaard, T., Kelstrup, C., Dmytriyev, A., Choudhary, Chunaram, Lundby, C. & Olsen, Jesper Velgaard, 30 Aug 2012, In: Cell Reports. 2, 2, p. 419-431 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Proteomics couples electrical remodelling to inflammation in a murine model of heart failure with sinus node dysfunction
Kahnert, K., Soattin, L., Mills, R. W., Wilson, C., Maurya, S., Sorrentino, A., Al-Othman, S., Tikhomirov, R., van de Vegte, Y. J., Hansen, F. B., Achter, J., Hu, W., Zi, M., Smith, M., van der Harst, P., Olesen, M. S., Olsen, K. B., Banner, J., Jensen, T. H. L., Zhang, H. & 3 others, , 2024, (E-pub ahead of print) In: Cardiovascular Research. cvae054.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues
Lundby, Alicia, Secher, A., Lage, K., Nordsborg, Nikolai Baastrup, Dmytriyev, A., Lundby, C. & Olsen, Jesper Velgaard, 6 Jun 2012, In: Nature Communications. 3, p. 1-10 10 p., Article 876.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative proteome comparison of human hearts with those of model organisms
Linscheid, N., Santos, A., Poulsen, P. C., Mills, Robert William, Callø, Kirstine, Leurs, U., Ye, J. Z., Stolte, C., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Lundegaard, Pia Rengtved, Olesen, Morten Steen Salling, Jensen, Lars Juhl, Olsen, Jesper Velgaard & Lundby, Alicia, 2021, In: PLOS Biology. 19, 4, 22 p., e3001144.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking
Linscheid, N., Logantha, S. J. R. J., Poulsen, C., Zhang, S., Schrölkamp, Maren, Egerod, Kristoffer Lihme, Thompson, J. J., Kitmitto, A., Galli, G., Humphries, M. J., Zhang, H., Pers, Tune H, Olsen, Jesper Velgaard, Boyett, M. & Lundby, Alicia, 2019, In: Nature Communications. 10, 19 p., 2889.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative proteomics characterization of acutely isolated primary adult rat cardiomyocytes and fibroblasts
Poulsen, P. C., Schrölkamp, Maren, Bagwan, N., Leurs, U., Humphries, E. S. A., Bomholzt, S. H., Nielsen, Morten Schak, Bentzen, Bo Hjorth, Olsen, Jesper Velgaard & Lundby, Alicia, 2020, In: Journal of Molecular and Cellular Cardiology. 143, p. 63-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative proteomics of human heart samples collected In vivo reveal the remodeled protein landscape of dilated left atrium without atrial fibrillation
Linscheid, N., Poulsen, P. C., Pedersen, I. D., Gregers, E., Svendsen, Jesper Hastrup, Olesen, Morten Steen Salling, Olsen, Jesper Velgaard, Delmar, M. & Lundby, Alicia, 2020, In: Molecular and Cellular Proteomics. 19, 7, p. 1132-1144Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rare truncating variants in the sarcomeric protein titin associate with familial and early-onset atrial fibrillation
Ahlberg, G., Refsgaard, L., Lundegaard, Pia Rengtved, Andreasen, Laura Korsholm, Ranthe, M. F., Linscheid, N., Nielsen, J. B., Melbye, M., Haunsø, Stig, Sajadieh, Ahmad, Camp, L., Olesen, Søren-Peter, Rasmussen, Simon, Lundby, Alicia, Ellinor, P. T., Holst, A. G., Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2018, In: Nature Communications. 9, 1, 11 p., 4316.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reevaluation of genetic variants previously associated with arrhythmogenic right ventricular cardiomyopathy integrating population-based cohorts and proteomics data
Ye, J. Z., Delmar, M., Lundby, Alicia & Olesen, Morten Steen Salling, 2019, In: Clinical Genetics. 96, 6, p. 506-514Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatial-proteomics reveal in-vivo phospho-signaling dynamics at subcellular resolution
Martinez Del Val, Ana, Bekker-Jensen, D. B., Steigerwald, S., Mehta, A., Tran, T., Sikorski, K., Torres Vega, Estefania, Kwasniewicz, E., Brynjólfsdóttir, S. H., Frankel, Lisa, Kjøbsted, Rasmus, Krogh, Nicolai, Lundby, Alicia, Bekker-Jensen, Simon Holst, Lund-Johansen, F. & Olsen, Jesper Velgaard, 2 Feb 2021, bioRxiv, p. 1-34, 34 p.Research output: Working paper › Preprint › Research
- Published
Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution
Martinez Del Val, Ana, Bekker-Jensen, D. B., Steigerwald, S., Koenig, Claire, Østergaard, Ole, Mehta, A., Tran, T., Sikorski, K., Torres Vega, Estefania, Kwasniewicz, E., Brynjólfsdóttir, S. H., Frankel, Lisa, Kjøbsted, Rasmus, Krogh, Nicolai, Lundby, Alicia, Bekker-Jensen, Simon Holst, Lund-Johansen, F. & Olsen, Jesper Velgaard, 2021, In: Nature Communications. 12, 1, 17 p., 7113.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural basis for KV7.1/KCNEx interactions in the IKs channel complex
Lundby, Alicia, Tseng, G. & Schmitt, Nicole, 2010, In: Heart Rhythm. 7, 5, p. 708-713Research output: Contribution to journal › Journal article › Research › peer-review
ID: 10426
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52 Genetic Loci Influencing Myocardial Mass
Research output: Contribution to journal › Journal article › Research › peer-review
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426
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Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
378
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Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking
Research output: Contribution to journal › Journal article › Research › peer-review
Published