Molecular Cardiology and Membrane Proteins
Blegdamsvej 3, 2200 København N.
The research in my laboratory is focused on ion channels and their roles especially in the regulation of the heart beat. I direct the Danish National Research Foundation Centre for Cardiac Arrhythmia encompassing about 70 colleagues at the Department of Biomedical Sciences, KU and at the Heart Centre, RH. This large research group makes it possible to work on a basic understanding of the regulation of the heart rhythm at a molecular level in the lab as well as with the patients in the clinic.
The challenge is to understand the biological mechanisms stabilizing the heart beat as well as on the changes in the cardiac muscle cells leading to instability and arrhythmia.
In addition to these studies we also work on other research projects aimed at developing new drugs for the treatment of these diseases and on the roles of ion channels in other physiological systems.
Primary fields of research
- Genetic causes of atrial fibrillation
- Pharmacological treatment of atrial fibrillatio
- Role of K channel subtypes in the regulation of the coronary circulation
- The Kv7.1 potassium channel: Role in the insulin response and in diabetes
- Targeting of neuronal ion channels
- Molecular interactions in ion channel complexes
Possible conflicts of interest
Member of the Board of Trustees of the Carlsberg Laboratory
Consultant to Acesion Pharma
Currently supervise 5 PhD students; have supervised 30 PhD students that have got their degree.