Tune H Pers
Associate Professor - Promotion Programme
Pers Group
Blegdamsvej 3B, Mærsk Tårnet, 8. sal, 2200 København N.
- 2024
- Published
An RNA-seq atlas of mouse brain areas during fasting and diet-induced obesity
Todorov, Petar Vladimirov, Klein, A. B., Egerod, Kristoffer Lihme, Clemmensen, Christoffer & Pers, Tune H, 2024, In: Scientific Data. 11, 8 p., 44.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R
Lund, Camilla, Ranea-Robles, Pablo, Falk, S., Belmont-Rausch, Dylan Matthew, Skovbjerg, G., Vibe-Petersen, V. K., Krauth, Nathalie, Skytte, J. L., Vana, V., Roostalu, U., Pers, Tune H, Lund, Jens & Clemmensen, Christoffer, 2024, In: Nature Communications. 15, 1192.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protocol for flow cytometry-assisted single-nucleus RNA sequencing of human and mouse adipose tissue with sample multiplexing
Gulko, A., Essene, A., Belmont-Rausch, Dylan Matthew, Veregge, M., Pant, D., Tenen, D., Kapel, Benedicte Schultz, Emont, M. P., Pers, Tune H, Rosen, E. D. & Tsai, L. T., 2024, In: STAR Protocols. 5, 1, 21 p., 102893.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
A single-cell, time-resolved profiling of Xenopus mucociliary epithelium reveals nonhierarchical model of development
Lee, J., Møller, A. F., Chae, S., Bussek-Sedzinski, Alexandra Maria, Park, T. J., Kim, Y., Lee, H. S., Pers, Tune H, Kwon, T., Sedzinski, Jakub & Natarajan, K. N., 2023, In: Science Advances. 9, 14, p. eadd5745 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adipogenic and SWAT cells separate from a common progenitor in human brown and white adipose depots
Palani, Nagendra Prasad, Horvath, C., Timshel, P. N., Folkertsma, P., Grønning, Alexander GB, Henriksen, T. I., Peijs, Lone, Jensen, V. H., Sun, W., Jespersen, N. Z., Wolfrum, C., Pers, Tune H, Nielsen, S. & Schéele, Camilla Charlotte Nielsen, 2023, In: Nature Metabolism. 5, 6, p. 996-1013 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessing household lifestyle exposures from consumer purchases, the My Purchases cohort
Møller, F. T., Junker, T. G., Sørensen, Kathrine Kold, Eves, C., Wohlfahrt, J., Dillner, J., Torp-Pedersen, Christian, Wilkowski, B., Chong, S., Pers, Tune H, Yakimov, V., Müller, H., Ethelberg, Steen & Melbye, M., 2023, In: Scientific Reports. 13, 12 p., 21601.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 and nicotine combination therapy engages hypothalamic and mesolimbic pathways to reverse obesity
Falk, S., Petersen, Jonas Odgaard, Svendsen, C. S. A., Leguizamon, Cesar Ramon Romero, Jørgensen, Søren Heide, Krauth, Nathalie, Ludwig, M. Q., Jørgensen, Kathrine Lundø, Roostalu, U., Hjort-Gregersen, G. S., Nielsen, D. A. G., Ejdrup, Aske Lykke, Pers, Tune H, Dmytriyeva, O., Hecksher-Soerensen, J., Gether, Ulrik, Kohlmeier, Kristi Anne & Clemmensen, Christoffer, 2023, In: Cell Reports. 42, 5, 18 p., 112466.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification
Lagou, V., Jiang, L., Ulrich, A., Zudina, L., González, K. S. G., Balkhiyarova, Z., Faggian, A., Maina, J. G., Chen, S., Todorov, P. V., Sharapov, S., David, A., Marullo, L., Mägi, R., Rujan, R. M., Ahlqvist, E., Thorleifsson, G., Gao, Η., Εvangelou, Ε., Benyamin, B. & 78 others, , 2023, In: Nature Genetics. 55, 9, p. 1448-1461 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Connectomics Reveals a Glucagon-Like Peptide 1 Sensitive Neural Circuit for Satiety
Webster, A. N., Becker, J. J., Li, C., Schwalbe, D. C., Kerspern, D., Karolczak, E. O., Godschall, E. N., Belmont-Rausch, Dylan Matthew, Pers, Tune H, Lutas, A., Habib, N., Güler, A. D., Krashes, M. J. & Campbell, J. N., 2023, bioRxiv, 47 p.Research output: Working paper › Preprint › Research
- Published
Molecular Consequences of Peripheral Influenza A Infection on Cell Populations in the Murine Hypothalamus
Lemcke, René, Jensen, Christine Egebjerg, Pagh-Berendtsen, Nicolai, Egerod, Kristoffer Lihme, Thomsen, Allan Randrup, Pers, Tune H, Christensen, Jan Pravsgaard & Kornum, Birgitte Rahbek, 2023, 31 p.Research output: Working paper › Preprint › Research
- Published
Molecular consequences of peripheral Influenza A infection on cell populations in the murine hypothalamus
Lemcke, René, Jensen, Christine Egebjerg, Pagh-Berendtsen, Nicolai, Egerod, Kristoffer Lihme, Thomsen, Allan Randrup, Pers, Tune H, Christensen, Jan Pravsgaard & Kornum, Birgitte Rahbek, 2023, In: eLife. 12, 28 p., RP87515.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Elucidating the relationship between migraine risk and brain structure using genetic data
International Headache Genetics Consortium, I. H. G. C., 1 Sep 2022, In: Brain. 145, 9, p. 3214-3224 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A single-cell atlas of human and mouse white adipose tissue
Emont, M. P., Jacobs, C., Essene, A. L., Pant, D., Tenen, D., Colleluori, G., Di Vincenzo, A., Jørgensen, A. M., Dashti, H., Stefek, A., McGonagle, E., Strobel, S., Laber, S., Agrawal, S., Westcott, G. P., Kar, A., Veregge, M. L., Gulko, A., Srinivasan, H., Kramer, Z. & 18 others, , 2022, In: Nature. 603, p. 926-933Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic analysis of dietary intake identifies new loci and functional links with metabolic traits
Merino, J., Dashti, H. S., Sarnowski, C., Lane, J. M., Todorov, Petar Vladimirov, Udler, M. S., Song, Y., Wang, H., Kim, J., Tucker, C., Campbell, J., Tanaka, T., Chu, A. Y., Tsai, L., Pers, Tune H, Chasman, D., Rutter, M. K., Dupuis, J., Florez, J. C. & Saxena, R., 2022, In: Nature Human Behaviour. 6, p. 155-163 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention
Wang, Z., Emmerich, A., Pillon, N. J., Moore, T., Hemerich, D., Cornelis, M. C., Mazzaferro, E., Broos, S., Ahluwalia, T. S., Bartz, T. M., Bentley, A. R., Bielak, L. F., Chong, M., Chu, A. Y., Berry, D., Dorajoo, R., Dueker, N. D., Kasbohm, E., Feenstra, B., Feitosa, M. F. & 32 others, , 2022, In: Nature Genetics. 54, p. 1332–1344 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study of febrile seizures implicates fever response and neuronal excitability genes
Skotte, L., Fadista, J., Bybjerg-Grauholm, J., Appadurai, V., Hildebrand, M. S., Hansen, T. F., Banasik, K., Grove, J., Albiñana, C., Geller, F., Bjurström, C. F., Vilhjálmsson, B. J., Coleman, M., Damiano, J. A., Burgess, R., Scheffer, I. E., Pedersen, O. B. V., Erikstrup, C., Westergaard, D., Nielsen, K. R. & 19 others, , 2022, In: Brain. 145, 2, p. 555–568Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hindbrain circuits in the control of eating behaviour and energy balance
Cheng, W., Gordian, D., Ludwig, M. Q., Pers, Tune H, Seeley, R. J. & Myers, M. G., 2022, In: Nature Metabolism. 4, 7, p. 826-835 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
Okbay, A., Wu, Y., Wang, N., Jayashankar, H., Bennett, M., Nehzati, S. M., Sidorenko, J., Kweon, H., Goldman, G., Gjorgjieva, T., Jiang, Y., Hicks, B., Tian, C., Hinds, D. A., Ahlskog, R., Magnusson, P. K. E., Oskarsson, S., Hayward, C., Campbell, A., Porteous, D. J. & 31 others, , 2022, In: Nature Genetics. 54, 4, p. 437-449 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Production of human entorhinal stellate cell-like cells by forward programming shows an important role of Foxp1 in reprogramming
Bergmann, T., Liu, Y., Skov, J., Mogus, L., Lee, J., Pfisterer, U., Handfield, L. F., Asenjo-Martinez, A., Lisa-Vargas, I., Seemann, S. E., Lee, J. T. H., Patikas, N., Kornum, B. R., Denham, M., Hyttel, P., Witter, M. P., Gorodkin, J., Pers, T. H., Hemberg, M., Khodosevich, K. & 1 others, , 2022, In: Frontiers in Cell and Developmental Biology. 10, 976549.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders
Blokland, G. A. M., Grove, J., Chen, C. Y., Cotsapas, C., Tobet, S., Handa, R., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M. & 35 others, , 2022, In: Biological Psychiatry. 91, 1, p. 107-117Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single-cell transcriptome and cell type-specific molecular pathways of human non-alcoholic steatohepatitis
Fred, Rikard Göran, Steen Pedersen, J., Thompson, J. J., Lee, J., Timshel, P. N., Stender, S., Rygg, M. O., Gluud, Lise Lotte, Bjerregaard Kristiansen, V., Bendtsen, Flemming, Hansen, Torben & Pers, Tune H, 2022, In: Scientific Reports. 12, 1, 13 p., 13484.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts
Ni, G., Zeng, J., Revez, J. A., Wang, Y., Zheng, Z., Ge, T., Restuadi, R., Kiewa, J., Nyholt, D. R., Coleman, J. R. I., Smoller, J. W., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A. & 21 others, , 2021, In: Biological Psychiatry. 90, 9, p. 611-620Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A genetic map of the mouse dorsal vagal complex and its role in obesity
Ludwig, M. Q., Cheng, W., Gordian, D., Lee, J., Paulsen, S. J., Hansen, S. N., Egerod, Kristoffer Lihme, Barkholt, P., Rhodes, C. J., Secher, A., Knudsen, L. B., Pyke, C., Myers, M. G. & Pers, Tune H, 2021, In: Nature Metabolism. 3, p. 530-545Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association and genetic overlap between clinical chemistry tests and migraine
Tanha, H. M. & The International Headache Genetics Consortium (IHGC), T. I. H. G. C. (., 2021, In: Cephalalgia. 41, 11-12, p. 1208-1221 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders
Andlauer, T. F. M., Guzman-Parra, J., Streit, F., Strohmaier, J., González, M. J., Gil Flores, S., Cabaleiro Fabeiro, F. J., del Río Noriega, F., Perez, F. P., Haro González, J., Orozco Diaz, G., de Diego-Otero, Y., Moreno-Küstner, B., Auburger, G., Degenhardt, F., Heilmann-Heimbach, S., Herms, S., Hoffmann, P., Frank, J., Foo, J. C. & 26 others, , 2021, In: Molecular Psychiatry. 26, 4, p. 1286-1298 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic insights into biological mechanisms governing human ovarian ageing
Ruth, K. S., Day, F. R., Hussain, J., Martinez-Marchal, A., Aiken, C. E., Azad, A., Thompson, D. J., Knoblochova, L., Abe, H., Tarry-Adkins, J. L., Gonzalez, J. M., Fontanillas, P., Claringbould, A., Bakker, O. B., Sulem, P., Walters, R. G., Terao, C., Turon, S., Horikoshi, M., Lin, K. & 36 others, , 2021, In: Nature. 596, p. 393-397Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells
Fardoos, R., Asowata, O. E., Herbert, N., Nyquist, S. K., Zungu, Y., Singh, A., Ngoepe, A., Mbano, I. M., Mthabela, N., Ramjit, D., Karim, F., Kuhn, W., Madela, F. G., Manzini, V. T., Anderson, F., Berger, B., Pers, Tune H, Shalek, A. K., Leslie, A. & Kløverpris, Henrik Nyhus, 2021, In: JCI insight. 6, 16, e148920.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human skeletal muscle CD90+ fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients
Farup, J., Just, J., de Paoli, F., Lin, L., Jensen, J. B., Billeskov, T., Roman, I. S., Cömert, C., Møller, A. B., Madaro, L., Groppa, E., Fred, R. G., Kampmann, U., Gormsen, L. C., Pedersen, S. B., Bross, P., Stevnsner, T., Eldrup, N., Pers, T. H., Rossi, F. M. V. & 2 others, , 2021, In: Cell Metabolism. 33, 11, p. 2201-2214.e11Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypothalamic hormone-sensitive lipase regulates appetite and energy homeostasis
Johnsen, Cecilie Hundahl, Kotzbeck, P., Burm, Hayley Beth, Christiansen, S. H., Pedersen, Lola Julie Torz, zmw799, zmw799, Madsen, M. P., Ratner, C., Serup, A. K., Thompson, J. J., Eichmann, T. O., Pers, Tune H, Woldbye, David Paul Drucker, Piomelli, D., Kiens, Bente, Zechner, R., Skov, Louise Julie & Holst, Birgitte, 2021, In: Molecular Metabolism. 47, 16 p., 101174.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour
Mills, M. C., Tropf, F. C., Brazel, D. M., van Zuydam, N., Vaez, A., Agbessi, M., Ahsan, H., Alves, I., Andiappan, A. K., Arindrarto, W., Awadalla, P., Battle, A., Beutner, F., Jan Bonder, M., Boomsma, D. I., Christiansen, M. W., Claringbould, A., Deelen, P., Esko, T., Favé, M-J. & 33 others, , 2021, In: Nature Human Behaviour. 5, p. 1717-1730Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Isolation and characterization of muscle stem cells, fibro-adipogenic progenitors, and macrophages from human skeletal muscle biopsies
Jensen, J. B., Møller, A. B., Just, J., Mose, M., de Paoli, F. V., Billeskov, T. B., Fred, Rikard Göran, Pers, Tune H, Pedersen, S. B., Petersen, K. K., Bjerre, M., Farup, J. & Jessen, N., 2021, In: American Journal of Physiology - Cell Physiology. 321, 2, p. C257-C268 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of hypothalamic MAPK/ERK signaling and central action of FGF1 in diabetes remission
Brown, Jenny, Bentsen, M. A., Belmont-Rausch, Dylan Matthew, Phan, B. A., Wieck, D., Wasanwala, H., Matsen, M. E., Acharya, N., Richardson, N. E., Zhao, X., Zhai, P., Secher, A., Morton, G. J., Pers, Tune H, Schwartz, M. W. & Scarlett, J. M., 2021, In: iScience. 24, 9, 19 p., 102944.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single-Cell Mapping of GLP-1 and GIP Receptor Expression in the Dorsal Vagal Complex
Ludwig, M. Q., Todorov, Petar Vladimirov, Egerod, Kristoffer Lihme, Olson, D. P. & Pers, Tune H, 2021, In: Diabetes. 70, 9, p. 1945-1955 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine
Guo, Y., Rist, P. M., Daghlas, I., Giulianini, F., Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., Farh, K. H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M. & 32 others, , 2020, In: Nature Communications. 11, 1, 3368.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cerebral small vessel disease genomics and its implications across the lifespan
Sargurupremraj, M., Suzuki, H., Jian, X., Sarnowski, C., Evans, T. E., Bis, J. C., Eiriksdottir, G., Sakaue, S., Terzikhan, N., Habes, M., Zhao, W., Armstrong, N. J., Hofer, E., Yanek, L. R., Hagenaars, S. P., Kumar, R. B., van den Akker, E. B., McWhirter, R. E., Trompet, S., Mishra, A. & 32 others, , 2020, In: Nature Communications. 11, 1, 18 p., 6285.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complement genes contribute sex-biased vulnerability in diverse disorders
Kamitaki, N., Sekar, A., Handsaker, R. E., de Rivera, H., Tooley, K., Morris, D. L., Taylor, K. E., Whelan, C. W., Tombleson, P., Loohuis, L. M. O., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H. & 33 others, , 2020, In: Nature. 582, 7813, p. 577-581 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic mapping of etiologic brain cell types for obesity
Timshel, P. N., Thompson, J. J. & Pers, Tune H, 2020, In: eLife. 9, 45 p., 55851.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Habitual sleep disturbances and migraine: a Mendelian randomization study
Daghlas, I., Vgontzas, A., Guo, Y., Chasman, D. I., Saxena, R., Pers, Tune H & International Headache Genetics Consortium, I. H. G. C., 2020, In: Annals of Clinical and Translational Neurology. 7, 12, p. 2370-2380 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis: [incl. Author Correction]
Pfisterer, U., Petukhov, V., Demharter, S., Meichsner, J., Thompson, J. J., Batiuk, M. Y., Martinez, A. A., Vasistha, Navneet A, Thakur, A., Mikkelsen, Jens D., Adorjan, I., Pinborg, Lars Hageman, Pers, Tune H, von Engelhardt, J., Kharchenko, P. V. & Khodosevich, K., 2020, In: Nature Communications. 11, 1, 19 p., 5038.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient
Rifes, P., Isaksson, M., Rathore, Gaurav Singh, Aldrin-Kirk, P., Moller, O. K., Barzaghi, G., Lee, J., Egerod, Kristoffer Lihme, Belmont-Rausch, Dylan Matthew, Parmar, M., Pers, Tune H, Laurell, T. & Kirkeby, Agnete, 2020, In: Nature Biotechnology. 38, p. 1265-1273 9 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Multi-omics characterization of a diet-induced obese model of non-alcoholic steatohepatitis
Ægidius, H. M., Veidal, S. S., Feigh, M., Hallenborg, P., Puglia, M., Pers, Tune H, Vrang, N., Jelsing, J., Kornum, Birgitte Rahbek, Blagoev, B. & Rigbolt, K. T. G., 2020, In: Scientific Reports. 10, 1, 12 p., 1148.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nationwide prediction of type 2 diabetes comorbidities
Dworzynski, P., Aasbrenn, M., Rostgaard, K., Melbye, M., Gerds, Thomas Alexander, Hjalgrim, H. & Pers, Tune H, 2020, In: Scientific Reports. 10, 13 p., 1776.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls
Coleman, J. R. I., Gaspar, H. A., Bryois, J., Byrne, E. M., Forstner, A. J., Holmans, P. A., de Leeuw, C. A., Mattheisen, M., McQuillin, A., Whitehead Pavlides, J. M., Pers, T. H., Ripke, S., Stahl, E. A., Steinberg, S., Trubetskoy, V., Trzaskowski, M., Wang, Y., Abbott, L., Abdellaoui, A., Adams, M. J. & 32 others, , 2020, In: Biological Psychiatry. 88, 2, p. 169-184 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission
Bentsen, M. A., Rausch, D. M., Mirzadeh, Z., Muta, K., Scarlett, J. M., Brown, J. M., Herranz-Pérez, V., Baquero, A. F., Thompson, J., Alonge, K. M., Faber, C. L., Kaiyala, K. J., Bennett, C., Pyke, C., Ratner, C., Egerod, K. L., Holst, B., Meek, T. H., Kutlu, B., Zhang, Y. & 9 others, , 2020, In: Nature Communications. 11, 1, 4458.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
scVAE: variational auto-encoders for single-cell gene expression data
Grønbech, Christopher Heje, Vording, M. F., Timshel, P., Sønderby, C. K., Pers, Tune H & Winther, Ole, 2020, In: Bioinformatics. 36, 16, p. 4415-4422 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
The developing Entorhinal cortex - a cellular map
Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Handfield, L., Asenjo Martinez, A., Seemann, Ernst Stefan, Witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Hemberg, M., Pers, Tune H & Hall, Vanessa Jane, 25 Nov 2019. 1 p.Research output: Contribution to conference › Conference abstract for conference › Communication
- Published
Genome-wide association study identifies 30 loci associated with bipolar disorder
eQTLGen Consortium, E. C., May 2019, In: Nature Genetics. 51, 5, p. 793-803Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Benchmarker: An Unbiased, Association-Data-Driven Strategy to Evaluate Gene Prioritization Algorithms
Fine, R. S., Pers, Tune H, Amariuta, T., Raychaudhuri, S. & Hirschhorn, J. N., 2019, In: American Journal of Human Genetics. 104, 6, p. 1025-1039Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
Karlsson Linnér, R., Biroli, P., Kong, E., Meddens, S. F. W., Wedow, R., Fontana, M. A., Lebreton, M., Tino, S. P., Abdellaoui, A., Hammerschlag, A. R., Nivard, M. G., Okbay, A., Rietveld, C. A., Timshel, P. N., Trzaskowski, M., Vlaming, R. D., Zünd, C. L., Bao, Y., Buzdugan, L., Caplin, A. H. & 31 others, , 2019, In: Nature Genetics. 51, 2, p. 245-257Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility
Patsopoulos, N. A., Baranzini, S. E., Santaniello, A., Shoostari, P., Cotsapas, C., Wong, G., Beecham, A. H., James, T., Replogle, J., Vlachos, I. S., McCabe, C., Pers, T. H., Brandes, A., White, C., Keenan, B., Cimpean, M., Winn, P., Panteliadis, I. P., Robbins, A., Andlauer, T. F. M. & 32 others, , 2019, In: Science. 365, 6460, eaav7188.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PAIRUP-MS: Pathway analysis and imputation to relate unknowns in profiles from mass spectrometry-based metabolite data
Hsu, Y. H., Churchhouse, C., Pers, Tune H, Mercader, J. M., Metspalu, A., Fischer, K., Fortney, K., Morgen, E. K., Gonzalez, C., Gonzalez, M. E., Esko, T. & Hirschhorn, J. N., 2019, In: PLOS Computational Biology. 15, 1, 26 p., e1006734.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia
Harold, D., Connolly, S., Riley, B. P., Kendler, K. S., McCarthy, S. E., McCombie, W. R., Richards, A., Owen, M. J., O'Donovan, M. C., Walters, J., Donnelly, P., Bates, L., Barroso, I., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Deloukas, P., Duncanson, A. & 32 others, , 2019, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 180, 3, p. 223-231 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Production of stellate cells from induced pluripotent stem cells to study Alzheimer's disease pathology
Mogus, L., Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Handfield, L., Asenjo Martinez, A., Seemann, Ernst Stefan, Witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Hemberg, M., Pers, Tune H & Hall, Vanessa Jane, 2019. 1 p.Research output: Contribution to conference › Conference abstract for conference › Communication
- Published
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution
Justice, A. E., Karaderi, T., Highland, H. M., Young, K. L., Graff, M., Lu, Y., Turcot, V., Auer, P. L., Fine, R. S., Guo, X., Schurmann, C., Lempradl, A., Marouli, E., Mahajan, A., Winkler, T. W., Locke, A. E., Medina-Gomez, C., Esko, T., Vedantam, S., Giri, A. & 31 others, , 2019, In: Nature Genetics. 51, 3, p. 452-469 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking
Linscheid, N., Logantha, S. J. R. J., Poulsen, C., Zhang, S., Schrölkamp, Maren, Egerod, Kristoffer Lihme, Thompson, J. J., Kitmitto, A., Galli, G., Humphries, M. J., Zhang, H., Pers, Tune H, Olsen, Jesper Velgaard, Boyett, M. & Lundby, Alicia, 2019, In: Nature Communications. 10, 19 p., 2889.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RhoA in tyrosine hydroxylase neurons regulates food intake and body weight via altered sensitivity to peripheral hormones
Skov, Louise Julie, Ratner, C., Hansen, Nikolaj Winther, Thompson, J. J., Egerod, Kristoffer Lihme, Burm, Hayley Beth, Dalbøge, L. S., Hedegaard, M. A., Brakebusch, Cord Herbert, Pers, Tune H, Perrier, Jean-Francois Marie & Holst, Birgitte, 2019, In: Journal of Neuroendocrinology. 31, 7, 13 p., UNSP e12761.Research output: Contribution to journal › Conference article › Research › peer-review
- Published
Sandwich cortial lamination and single-cell analysis decodes the developing spatial processing system
Liu, Y., Bergmann, T. B., Lee, J., Pfisterer, U. G., Handfield, L-F., Mori, Y., Asenjo Martinez, A., Lisa Vargas, I., Seemann, E. S., Lee, J. T. H., Patikis, N., Peralvo Vidal, J. M., Pihl, M., Kornum, B. R., Thomsen, P. D., Hyttel, P., Witter, M., Khodosevich, K., Gorodkin, J., Hemberg, M. & 2 others, , 2019. 45 p.Research output: Contribution to conference › Paper › Communication
- Published
The developing Entorhinal Cortex – a cellular map
Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Asenjo Martinez, A., Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Pers, Tune H & Hall, Vanessa Jane, 2019.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Tracing the origin of adult intestinal stem cells
Guiu, J., Hannezo, E., Yui, S., Demharter, S., Ulyanchenko, Svetlana, Maimets, Martti, Jørgensen, A., Perlman, S., Lundvall, L., Mamsen, L. S., Larsen, A., Olesen, R. H., Andersen, C. Y., Thuesen, L. L., Hare, Kristine Juul, Pers, Tune H, Khodosevich, Konstantin, Simons, B. D. & Jensen, Kim Bak, 2019, In: Nature. 570, 7759, p. 107-111Research output: Contribution to journal › Letter › Research › peer-review
- Published
Uncovering the anatomical and molecular landscape of the starting point of Alzheimer’s disease in the brain
Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Asenjo Martinez, A., Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Pers, Tune H & Hall, Vanessa Jane, 2019.Research output: Contribution to conference › Conference abstract for conference › Research
- 2018
- Published
Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders
Ligthart, S., Vaez, A., Vosa, U., Stathopoulou, M. G., de Vries, P. S., Prins, B. P., Van der Most, P. J., Tanaka, T., Naderi, E., Rose, L. M., Wu, Y., Karlsson, R., Barbalic, M., Lin, H., Pool, R., Zhu, G., Mace, A., Sidore, C., Trompet, S., Mangino, M. & 266 others, , 1 Nov 2018, In: American Journal of Human Genetics. 103, 5, p. 691-706Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes
Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium douglas.ruderfer@vanderbilt.edu, B. D. A. S. W. G. O. T. P. G. C. D. R. E., Psychosis Endophenotypes International Consortium, P. E. I. C. & Wellcome Trust Case-Control Consortium, W. T. C. C., 14 Jun 2018, In: Cell. 173, 7, p. 1705-1715.e16Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes
Bonàs-Guarch, S., Guindo-Martínez, M., Miguel-Escalada, I., Grarup, N., Sebastian, D., Rodriguez-Fos, E., Sánchez, F., Planas-Fèlix, M., Cortes-Sánchez, P., González, S., Timshel, P., Pers, T. H., Morgan, C. C., Moran, I., Atla, G., González, J. R., Puiggros, M., Martí, J., Andersson, E. A., Díaz, C. & 23 others, , 22 Jan 2018, In: Nature Communications. 9, 14 p., 321.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
Turcot, V., Lu, Y., Highland, H. M., Bang, L. E., Benn, M., Kamstrup, P. R., Bork-Jensen, J., Frikke-Schmidt, R., Gjesing, A. P., Grarup, N., Hansen, T., Have, C. T., Jørgensen, T., Nielsen, S. F., Linneberg, A. R., Pedersen, O., Pers, T. H., Vestergaard, H., Nordestgaard, B., Tybjærg-Hansen, A. & 15 others, , 1 Jan 2018, In: Nature Genetics. 50, p. 26-41 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Age at first birth in women is genetically associated with increased risk of schizophrenia
Ni, G., Gratten, J., Wray, N. R., Lee, S. H., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F. & 281 others, , 2018, In: Scientific Reports. 8, 1, p. 1-14 10168.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
Lee, J. J., Wedow, R., Okbay, A., Kong, E., Maghzian, O., Zacher, M., Tuan Anh Nguyen-Viet, Bowers, P., Sidorenko, J., Linner, R. K., Fontana, M. A., Kundu, T., Lee, C., Li, H., Li, R., Royer, R., Timshel, P. N., Walters, R. K., Willoughby, E. A., Yengo, L. & 58 others, , 2018, In: Nature Genetics. 50, 8, p. 1112-+Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association analyses identify 39 new susceptibility loci for diverticular disease
Maguire, L. H., Handelman, S. K., Du, X., Chen, Y., Pers, Tune H & Speliotes, E. K., 2018, In: Nature Genetics. 50, 10, p. 1359-1365Research output: Contribution to journal › Letter › Research › peer-review
- Published
Molecular genetic overlap between migraine and major depressive disorder
Yang, Y., Zhao, H., Boomsma, D. I., Ligthart, L., Belin, A. C., Smith, G. D., Esko, T., Freilinger, T. M., Hansen, T. F., Ikram, M. A., Kallela, M., Kubisch, C., Paraskevi, C., Strachan, D. P., Wessman, M., Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T. & 30 others, , 2018, In: European Journal of Human Genetics. 26, 8, p. 1202-1216 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The developmental neurogenic niche of the Entorhinal cortex revealed by single-cell transcriptomics.
Bergmann, T. B., Liu, Y., Lee, J., Peralvo Vidal, Juan Miguel, Mori, Yuki, Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Gorodkin, Jan, Hall, Vanessa Jane & Pers, Tune H, 2018.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Uncovering the anatomical and molecular landscape of the developing entorhinal cortex.
Liu, Y., Bergmann, T. B., Peralvo Vidal, Juan Miguel, Lee, J., Mori, Yuki, Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Gorodkin, Jan, Hyttel, P., Pers, Tune H, witter, M. & Hall, Vanessa Jane, 2018.Research output: Contribution to conference › Conference abstract for conference › Research
- 2017
- Published
A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk
Manning, A., Highland, H. M., Gasser, J., Sim, X., Tukiainen, T., Fontanillas, P., Grarup, N., Rivas, M. A., Mahajan, A., Locke, A. E., Cingolani, P., Pers, T. H., Viñuela, A., Brown, A. A., Wu, Y., Flannick, J., Fuchsberger, C., Gamazon, E. R., Gaulton, K. J., Im, H. K. & 243 others, , Dec 2017, In: Diabetes. 66, p. 2019-2032 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A molecular census of arcuate hypothalamus and median eminence cell types
Campbell, J. N., Macosko, E. Z., Fenselau, H., Pers, Tune H, Lyubetskaya, A., Tenen, D., Goldman, M., Verstegen, A. M. J., Resch, J. M., McCarroll, S. A., Rosen, E. D., Lowell, B. B. & Tsai, L. T., Mar 2017, In: Nature Neuroscience. 20, 3, p. 484-496 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rare and low-frequency coding variants alter human adult height
Marouli, E., Graff, M., Medina-Gomez, C., Lo, K. S., Wood, A. R., Kjaer, T. R., Fine, R. S., Lu, Y., Schurmann, C., Highland, H. M., Rüeger, S., Thorleifsson, G., Justice, A. E., Lamparter, D., Stirrups, K. E., Turcot, V., Young, K. L., Winkler, T. W., Esko, T., Karaderi, T. & 31 others, , 9 Feb 2017, In: Nature. 542, 7640, p. 186-190 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans
Scott, R. A., Scott, L. J., Mägi, R., Marullo, L., Gaulton, K. J., Kaakinen, M., Pervjakova, N., Pers, T. H., Johnson, A. D., Eicher, J. D., Jackson, A. U., Ferreira, T., Lee, Y., Ma, C., Steinthorsdottir, V., Thorleifsson, G., Qi, L., Van Zuydam, N. R., Mahajan, A., Chen, H. & 155 others, , 2017, In: Diabetes. 66, 11, p. 2888-2902Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic correlation between amyotrophic lateral sclerosis and schizophrenia
McLaughlin, R. L., Schijven, D., Van Rheenen, W., Van Eijk, K. R., O'Brien, M., Kahn, R. S., Ophoff, R. A., Goris, A., Bradley, D. G., Al-Chalabi, A., Van Den Berg, L. H., Luykx, J. J., Hardiman, O., Veldink, J. H., Shatunov, A., Dekker, A. M., Diekstra, F. P., Pulit, S. L., Van Der Spek, R. A. A., Van Doormaal, P. T. C. & 31 others, , 2017, In: Nature Communications. 8, 14774.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Shared genetic variants suggest common pathways in allergy and autoimmune diseases
Kreiner, E., Waage, J., Standl, M., Brix, S., Pers, T. H., Couto Alves, A., Warrington, N. M., Tiesler, C. M., Fuertes, E., Franke, L., Hirschhorn, J. N., James, A., Simpson, A., Tung, J. Y., Koppelman, G. H., Postma, D. S., Pennell, C. E., Jarvelin, M-R., Custovic, A., Timpson, N. & 6 others, , 2017, In: The Journal of allergy and clinical immunology. 140, 3, p. 771-781Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Gene set analysis for interpreting genetic studies
Pers, Tune H, 1 Oct 2016, In: Human Molecular Genetics. 25, R2, p. R133-R140 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study
Johnson, E. C., Bjelland, D. W., Howrigan, D. P., Abdellaoui, A., Breen, G., Borglum, A. D., Cichon, S., Degenhardt, F., Forstner, A. J., Frank, J., Genovese, G., Heilmann-Heimbach, S., Herms, S., Hoffman, P., Maier, W., Mattheisen, M., Morris, D. W., Mowry, B. J., Müller-Mhysok, B., Neale, B. M. & 297 others, , Oct 2016, In: PLOS Genetics. 12, 10, 20 p., e1006343.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
52 Genetic Loci Influencing Myocardial Mass
van der Harst, P., van Setten, J., Verweij, N., Vogler, G., Franke, L., Maurano, M. T., Wang, X., Mateo Leach, I., Eijgelsheim, M., Sotoodehnia, N., Hayward, C., Sorice, R., Meirelles, O., Lyytikäinen, L-P., Polašek, O., Tanaka, T., Arking, D. E., Ulivi, S., Trompet, S., Müller-Nurasyid, M. & 140 others, , 27 Sep 2016, In: Journal of the American College of Cardiology. 68, 13, p. 1435-48 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
Ehret, G. B., Ferreira, T., Chasman, D. I., Jackson, A. U., Schmidt, E. M., Johnson, T., Thorleifsson, G., Luan, J., Donnelly, L. A., Kanoni, S., Petersen, A-K., Pihur, V., Strawbridge, R. J., Shungin, D., Hughes, M. F., Meirelles, O., Kaakinen, M., Bouatia-Naji, N., Kristiansson, K., Shah, S. & 31 others, , 12 Sep 2016, In: Nature Genetics. 48, 10, p. 1171-1184 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T., Pers, T. H., Farh, K-H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., McMahon, G., Ligthart, L., Terwindt, G. M., Kallela, M., Freilinger, T. M., Ran, C., Gordon, S. G., Stam, A. H. & 31 others, , Aug 2016, In: Nature Genetics. 48, 8, p. 856-66 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study identifies 74 loci associated with educational attainment
Okbay, A., Beauchamp, J. P., Fontana, M. A., Lee, J. J., Pers, T. H., Rietveld, C. A., Turley, P., Chen, G-B., Emilsson, V., Meddens, S. F. W., Oskarsson, S., Pickrell, J. K., Thom, K., Timshel, P. N., de Vlaming, R., Abdellaoui, A., Ahluwalia, T. V. S., Bacelis, J., Baumbach, C., Bjornsdottir, G. & 31 others, , 26 May 2016, In: Nature. 533, 7604, p. 539-42 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci
Ellinghaus, D., Jostins, L., Spain, S. L., Cortes, A., Bethune, J., Han, B., Park, Y. R., Raychaudhuri, S., Pouget, J. G., Hübenthal, M., Folseraas, T., Wang, Y., Esko, T., Metspalu, A., Westra, H-J., Franke, L., Pers, T. H., Weersma, R. K., Collij, V., D'Amato, M. & 26 others, , May 2016, In: Nature Genetics. 48, 5, p. 510-521 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
Lu, Y., Day, F. R., Gustafsson, S., Buchkovich, M. L., Na, J., Bataille, V., Cousminer, D. L., Dastani, Z., Drong, A. W., Esko, T., Evans, D. M., Falchi, M., Feitosa, M. F., Ferreira, T., Hedman, Å. K., Haring, R., Hysi, P. G., Iles, M. M., Justice, A. E., Kanoni, S. & 239 others, , 1 Feb 2016, In: Nature Communications. 7, p. 1-15 15 p., 10495.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comprehensive analysis of schizophrenia-associated loci highlights ion channel pathways and biologically plausible candidate causal genes
Pers, Tune H, Timshel, P., Ripke, S., Lent, S., Sullivan, P. F., O'Donovan, M. C., Franke, L., Hirschhorn, J. N. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, S. W. G. O. T. P. G. C., 10 Jan 2016, In: Human Molecular Genetics. 25, 6, p. 1247-1254 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index
Felix, J. F., Bradfield, J. P., Monnereau, C., van der Valk, R. J. P., Stergiakouli, E., Chesi, A., Gaillard, R., Feenstra, B., Thiering, E., Kreiner-Møller, E., Mahajan, A., Pitkänen, N., Joro, R., Cavadino, A., Huikari, V., Franks, S., Groen-Blokhuis, M. M., Cousminer, D. L., Marsh, J. A., Lehtimäki, T. & 31 others, , 2016, In: Human Molecular Genetics. 25, 2, p. 389-403Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels
Kilpeläinen, T. O., Carli, J. F. M., Skowronski, A. A., Sun, Q., Kriebel, J., Feitosa, M. F., Hedman, Å. K., Drong, A. W., Hayes, J. E., Zhao, J., Pers, T. H., Schick, U., Grarup, N., Kutalik, Z., Trompet, S., Mangino, M., Kristiansson, K., Beekman, M., Lyytikäinen, L-P., Eriksson, J. & 157 others, , 2016, In: Nature Communications. 7, 14 p., 10494.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Gene-based meta-analysis of genome-wide association studies implicates new loci involved in obesity
Hägg, S., Ganna, A., Van Der Laan, S. W., Esko, T., Pers, Tune H, Locke, A. E., Berndt, S. I., Justice, A. E., Kahali, B., Siemelink, M. A., Pasterkamp, G., Strachan, D. P., Speliotes, E. K., North, K. E., Loos, Ruth, Hirschhorn, J. N., Pawitan, Y., Ingelsson, E. & GIANT Consortium, G. C., 1 Dec 2015, In: Human Molecular Genetics. 24, 23, p. 6849-60 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Population genetic differentiation of height and body mass index across Europe
Robinson, M. R., Hemani, G., Medina-Gomez, C., Mezzavilla, M., Esko, T., Shakhbazov, K., Powell, J. E., Vinkhuyzen, A., Berndt, S. I., Gustafsson, S., Justice, A. E., Kahali, B., Locke, A. E., Pers, T. H., Vedantam, S., Wood, A. R., van Rheenen, W., Andreassen, O. A., Gasparini, P., Metspalu, A. & 23 others, , Nov 2015, In: Nature Genetics. 47, 11, p. 1357-62, 2 unpag. Methods 8 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
A novel common variant in DCST2 is associated with length in early life and height in adulthood
van der Valk, R. J. P., Kreiner-Møller, E., Kooijman, M. N., Guxens, M., Stergiakouli, E., Sääf, A., Bradfield, J. P., Geller, F., Hayes, M. G., Cousminer, D. L., Körner, A., Thiering, E., Curtin, J. A., Myhre, R., Huikari, V., Joro, R., Kerkhof, M., Warrington, N. M., Pitkänen, N., Ntalla, I. & 31 others, , 15 Feb 2015, In: Human Molecular Genetics. 24, 4, p. 1155-68 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic studies of body mass index yield new insights for obesity biology
Locke, A. E., Kahali, B., Berndt, S. I., Justice, A. E., Pers, T. H., Day, F. R., Powell, C., Vedantam, S., Buchkovich, M. L., Yang, J., Croteau-Chonka, D. C., Esko, T., Fall, T., Ferreira, T., Gustafsson, S., Kutalik, Z., Luan, J., Mägi, R., Randall, J. C., Winkler, T. W. & 31 others, , 12 Feb 2015, In: Nature. 518, 7538, p. 197-206 24 p., 14177.Research output: Contribution to journal › Journal article › Research › peer-review
SNPsnap: a Web-based tool for identification and annotation of matched SNPs
Pers, Tune H, Timshel, P. & Hirschhorn, J. N., 2015, In: Bioinformatics. 31, 3, p. 418-420 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Genome-wide association analyses identify variants in developmental genes associated with hypospadias
Geller, F., Feenstra, B., Carstensen, L., Pers, Tune H, van Rooij, I. A. L. M., Korberg, I. B., Choudhry, S., Karjalainen, J. M., Schnack, T. H., Hollegaard, M. V., Feitz, W. F. J., Roeleveld, N., Hougaard, D. M., Hirschhorn, J. N., Franke, L., Baskin, L. S., Nordenskjold, A., van der Zanden, L. F. M. & Melbye, M., Sep 2014, In: Nature Genetics. 46, 9, p. 957-+Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization
Bønnelykke, K., Matheson, M. C., Pers, T. H., Granell, R., Strachan, D. P., Alves, A. C., Linneberg, A., Curtin, J. A., Warrington, N. M., Standl, M., Kerkhof, M., Jonsdottir, I., Bukvic, B. K., Kaakinen, M., Sleimann, P., Thorleifsson, G., Thorsteinsdottir, U., Schramm, K., Baltic, S., Kreiner-Møller, E. & 47 others, , 2013, In: Nature Genetics. 45, p. 902-906 5 p.Research output: Contribution to journal › Journal article › Communication
- 2011
- Published
Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes
Pers, T. H., Hansen, N. T., Hansen, K. L., Koefoed, P., Dworzynski, P., Miller, M. L., Flint, T. J., Mellerup, E., Dam, H., Andreassen, O. A., Djurovic, S., Melle, I., Børglum, A. D., Werge, T., Purcell, S., Ferreira, M. A., Kouskoumvekaki, I., Workman, C., Hansen, T., Mors, O. & 1 others, , 11 Apr 2011, In: Genetic Epidemiology. 35, 5, p. 318-332 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein interaction-based genome-wide analysis of incident coronary heart disease
Jensen, Majken Karoline, Pers, Tune H, Dworzynski, P., Girman, C. J., Brunak, Søren & Rimm, E. B., 2011, In: Circulation: Cardiovascular Genetics. 4, 5, p. 549-56 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
The validation and assessment of machine learning: a game of prediction from high-dimensional data
Pers, Tune H, Albrechtsen, Anders, Holst, C., Sørensen, Thorkild I.A. & Gerds, Thomas Alexander, 2009, In: PLoS ONE. 4, 8, p. e6287Research output: Contribution to journal › Journal article › Research › peer-review
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52 Genetic Loci Influencing Myocardial Mass
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
374
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Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
181
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Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes
Research output: Contribution to journal › Journal article › Research › peer-review
Published