Thor Grundtvig Theander
Professor
Centre for Medical Parasitology
Blegdamsvej 3, 2200 København N, Building: 07-11-17
CMP
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-11-TR4
Member of:
CMP-BIOENGINEERING
- 2012
- Published
The effect of adjuvants on the immune response induced by a DBL4e-ID4 VAR2CSA based Plasmodium falciparum vaccine against placental malaria
Pinto, V. V., Salanti, Ali, Joergensen, L. M., Dahlbäck, M., Resende, M., Ditlev, S. B., Agger, E. M., Arnot, D. E., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2012, In: Vaccine. 30, 3, p. 572-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Prevalence of Single Nucleotide Polymorphisms in the Plasmodium falciparum Multidrug Resistance Gene (Pfmdr-1) in Korogwe District in Tanzania Before and After Introduction of Artemisinin-Based Combination Therapy
Thomsen, T. T., Ishengoma, D. S., Mmbando, B. P., Lusingu, J. P., Vestergaard, L. S., Theander, Thor Grundtvig, Lemnge, M. M., Bygbjerg, Ib Christian & Alifrangis, Michael, 1 Dec 2011, In: American Journal of Tropical Medicine and Hygiene. 85, 6, p. 979-83 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pattern of pre-existing IgG subclass responses to a panel of asexual stage malaria antigens reported during the lengthy dry season in Daraweesh, Sudan
Nasr, A., Iriemenam, N. C., Troye-Blomberg, M., Arnot, D., Theander, Thor Grundtvig, Berzins, K., Giha, H. A. & Elghazali, G., 1 Oct 2011, In: Scandinavian Journal of Immunology. 74, 4, p. 390-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Measurement of lumefantrine and its metabolite in plasma by high performance liquid chromatography with ultraviolet detection
Khalil, I. F., Abildrup, U., Alifrangis, L. H., Maiga, D., Alifrangis, Michael, Hoegberg, L., Vestergaard, L. S., Persson, O. P., Nyagonde, N., Lemnge, M. M., Theander, Thor Grundtvig & Bygbjerg, Ib Christian, 5 Jan 2011, In: Journal of Pharmaceutical and Biomedical Analysis. 54, 1, p. 168-72 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Accuracy of malaria rapid diagnostic tests in community studies and their impact on treatment of malaria in an area with declining malaria burden in north-eastern Tanzania
Ishengoma, D. S., Francis, F., Mmbando, B. P., Lusingu, J. P., Magistrado, P., Alifrangis, Michael, Theander, Thor Grundtvig, Bygbjerg, Ib Christian & Lemnge, M. M., 1 Jan 2011, In: Malaria Journal. 10, p. 176Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential induction of functional IgG using the Plasmodium falciparum placental malaria vaccine candidate VAR2CSA
Pinto, V. V., Ditlev, S. B., Jensen, K. E., Resende, M., Dahlbäck, M., Andersen, G., Andersen, P., Theander, Thor Grundtvig, Salanti, Ali & Nielsen, Morten Agertoug, 1 Jan 2011, In: P L o S One. 6, 3, p. e17942Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites
Bejon, P., Turner, Louise, Lavstsen, Thomas, Cham, G., Olotu, A., Drakeley, C. J., Lievens, M., Vekemans, J., Savarese, B., Lusingu, J., von Seidlein, L., Bull, P. C., Marsh, K. & Theander, Thor Grundtvig, 1 Jan 2011, In: P L o S One. 6, 6, p. e21711Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibodies against PfEMP1, RIFIN, MSP3 and GLURP are acquired during controlled Plasmodium falciparum malaria infections in naïve volunteers
Turner, Louise, Wang, Christian William, Lavstsen, Thomas, Mwakalinga, S. B., Sauerwein, R. W., Hermsen, C. C. & Theander, Thor Grundtvig, 2011, In: P L o S One. 6, 12, p. e29025Research output: Contribution to journal › Journal article › Research › peer-review
- Published
First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children
Agnandji, S. T., Lell, B., Soulanoudjingar, S. S., Fernandes, J. F., Abossolo, B. P., Conzelmann, C., Methogo, B. G. N. O., Doucka, Y., Flamen, A., Mordmüller, B., Issifou, S., Kremsner, P. G., Sacarlal, J., Aide, P., Lanaspa, M., Aponte, J. J., Nhamuave, A., Quelhas, D., Bassat, Q., Mandjate, S. & 31 others, , 2011, In: New England Journal of Medicine. 365, 20, p. 1863-75 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High efficacy of anti DBL4e-VAR2CSA antibodies in inhibition of CSA-binding Plasmodium falciparum-infected erythrocytes from pregnant women
Magistrado, P. A., Minja, D., Doritchamou, J., Ndam, N. T., John, D., Schmiegelow, Christentze, Massougbodji, A., Dahlbäck, M., Ditlev, S. B., Pinto, V. V., Resende, M., Lusingu, J., Theander, Thor Grundtvig, Salanti, Ali & Nielsen, Morten Agertoug, 2011, In: Vaccine. 29, 3, p. 437-43 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Positive selection of Plasmodium falciparum parasites with multiple var2csa-type PfEMP1 genes during the course of infection in pregnant women
Sander, A. F., Salanti, Ali, Lavstsen, Thomas, Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Leke, R. G. F., Lo, Y. Y., Bobbili, N., Arnot, D. E. & Taylor, D. W., 2011, In: Journal of Infectious Diseases. 203, 11, p. 1679-85 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatial variation and socio-economic determinants of Plasmodium falciparum infection in northeastern Tanzania
Mmbando, B. P., Kamugisha, M. L., Lusingu, J. P., Francis, F., Ishengoma, D. S., Theander, Thor Grundtvig, Lemnge, M. M. & Scheike, Thomas, 2011, In: Malaria Journal. 10, 1, p. 145Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The chondroitin sulfate A-binding site of the VAR2CSA protein involves multiple N-terminal domains
Dahlbäck, M., Jørgensen, L. M., Nielsen, Morten Agertoug, Clausen, T. M., Ditlev, S. B., Resende, M., Pinto, V. V., Arnot, D. E., Theander, Thor Grundtvig & Salanti, Ali, 2011, In: The Journal of Biological Chemistry. 286, 18, p. 15908-17 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Plasmodium falciparum erythrocyte membrane protein 1 diversity in seven genomes - divide and conquer
Rask, T. S., Hansen, D. A., Theander, Thor Grundtvig, Gorm Pedersen, A. & Lavstsen, Thomas, 2010, In: P L o S Computational Biology. 6, 9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A progressive declining in the burden of malaria in north-eastern Tanzania
Mmbando, B. P., Vestergaard, L. S., Kitua, A. Y., Lemnge, M. M., Theander, Thor Grundtvig & Lusingu, J. P. A., 2010, In: Malaria Journal. 9, p. 216Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Age-dependent association between IgG2 and IgG3 subclasses to Pf332-C231 antigen and protection from malaria, and induction of protective antibodies by sub-patent malaria infections, in Daraweesh
Giha, H. A., Nasr, A., Iriemenam, N. C., Balogun, H. A., Arnot, D., Theander, Thor Grundtvig, Troye-Blomberg, M., Berzins, K. & ElGhazali, G., 2010, In: Vaccine. 28, 7, p. 1732-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of a single nucleotide polymorphism in the C-reactive protein gene (-286) with susceptibility to Plasmodium falciparum malaria
Giha, H. A., Nasr, A., Ekström, M., Israelsson, E., Arambepola, G., Arnot, D., Theander, Thor Grundtvig, Troye-Blomberg, M., Berzins, K., Tornvall, P. & ElGhazali, G., 2010, In: Molecular Medicine. 16, 1-2, p. 27-33 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clustering of malaria treatment failure (TF) in Daraweesh: hints for host genetic susceptibility to TF with emphasis on immune-modulating SNPs
Giha, H. A., ElGhazali, G., Nasr, A., Iriemenam, N. C., Berzins, K., Troye-Blomberg, M., Theander, Thor Grundtvig & Arnot, D., 2010, In: Infection, Genetics and Evolution. 10, 4, p. 481-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Full-length recombinant Plasmodium falciparum VAR2CSA binds specifically to CSPG and induces potent parasite adhesion blocking antibodies
Khunrae, P., Dahlbäck, M., Nielsen, Morten Agertoug, Andersen, G., Ditlev, S. B., Resende, M., Pinto, V. V., Theander, Thor Grundtvig, Higgins, M. K. & Salanti, Ali, 2010, In: Journal of Molecular Biology. 397, p. 826-834Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian children
Cham, G. K. K., Turner, Louise, Kurtis, J. D., Mutabingwa, T., Fried, M., Jensen, Anja Ramstedt, Lavstsen, Thomas, Hviid, Lars, Duffy, P. E. & Theander, Thor Grundtvig, 2010, In: Infection and Immunity. 78, 11, p. 4653-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of a major rif transcript common to gametocytes and sporozoites of Plasmodium falciparum
Wang, Christian William, Mwakalinga, S. B., Sutherland, C. J., Schwank, S., Sharp, S., Hermsen, C. C., Sauerwein, R. W., Theander, Thor Grundtvig & Lavstsen, Thomas, 2010, In: Malaria Journal. 9, 1, p. 147Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insect cells are superior to Escherichia coli in producing malaria proteins inducing IgG targeting PfEMP1 on infected erythrocytes
Victor, M. E., Bengtsson, A., Andersen, G., Bengtsson, D., Lusingu, J. P., Vestergaard, L. S., Arnot, D. E., Theander, Thor Grundtvig, Joergensen, L. & Jensen, Anja Ramstedt, 2010, In: Malaria Journal. 9, p. 325Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Several domains from VAR2CSA can induce Plasmodium falciparum adhesion-blocking antibodies
Salanti, Ali, Resende, M., Ditlev, S. B., Pinto, V. V., Dahlbäck, M., Andersen, G., Manczak, T., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2010, In: Malaria Journal. 9, 1, p. 11Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Surface co-expression of two different PfEMP1 antigens on single Plasmodium falciparum-infected erythrocytes facilitates binding to ICAM1 and PECAM1
Joergensen, L., Bengtsson, D. C., Bengtsson, A., Ronander, E., Berger, S. S., Turner, Louise, Dalgaard, M. B., Cham, G. K. K., Victor, M. E., Lavstsen, Thomas, Theander, Thor Grundtvig, Arnot, D. E. & Jensen, Anja Ramstedt, 2010, In: PLoS Pathogens. 6, 9, p. e1001083Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The kinetics of antibody binding to Plasmodium falciparum VAR2CSA PfEMP1 antigen and modelling of PfEMP1 antigen packing on the membrane knobs
Joergensen, L. M., Salanti, Ali, Dobrilovic, T., Barfod, Lea Klingenberg, Hassenkam, Tue, Theander, Thor Grundtvig, Hviid, Lars & Arnot, D. E., 2010, In: Malaria Journal. 9, 1, p. 100Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Antigen-specific influence of GM/KM allotypes on IgG isotypes and association of GM allotypes with susceptibility to Plasmodium falciparum malaria
Giha, H. A., Nasr, A., Iriemenam, N. C., Arnot, D., Troye-Blomberg, M., Theander, Thor Grundtvig, Berzins, K., ElGhazali, G. & Pandey, J. P., 2009, In: Malaria Journal. 8, 1, p. 306Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chondroitin sulphate A (CSA)-binding of single recombinant Duffy-binding-like domains is not restricted to Plasmodium falciparum Erythrocyte Membrane Protein 1 expressed by CSA-binding parasites
Resende, M., Ditlev, S. B., Nielsen, Morten Agertoug, Bodevin, S., Bruun, S., Pinto, V. V., Clausen, Henrik, Turner, Louise, Theander, Thor Grundtvig, Salanti, Ali & Dahlbäck, M., 2009, In: International Journal for Parasitology. 39, 11, p. 1195-204 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Five-year surveillance of molecular markers of Plasmodium falciparum antimalarial drug resistance in Korogwe District, Tanzania: accumulation of the 581G mutation in the P. falciparum dihydropteroate synthase gene
Alifrangis, Michael, Lusingu, J. P., Mmbando, B., Dalgaard, M. B., Vestergaard, L. S., Ishengoma, D., Khalil, I. F., Theander, Thor Grundtvig, Lemnge, M. M. & Bygbjerg, Ib Christian, 2009, In: American Journal of Tropical Medicine and Hygiene. 80, 4, p. 523-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Induction of adhesion-inhibitory antibodies against placental Plasmodium falciparum parasites by using single domains of VAR2CSA
Nielsen, Morten Agertoug, Pinto, V. V., Resende, M., Dahlbäck, M., Ditlev, S. B., Theander, Thor Grundtvig & Salanti, Ali, 2009, In: Infection and Immunity. 77, 6, p. 2482-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Parasite threshold associated with clinical malaria in areas of different transmission intensities in north eastern Tanzania
Mmbando, B. P., Lusingu, J. P., Vestergaard, L. S., Lemnge, M. M., Theander, Thor Grundtvig & Scheike, T. H., 2009, In: BMC Medical Research Methodology. 9, p. 75Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preferential transcription of conserved rif genes in two phenotypically distinct Plasmodium falciparum parasite lines
Wang, Christian William, Magistrado, P. A., Nielsen, Morten Agertoug, Theander, Thor Grundtvig & Lavstsen, Thomas, 2009, In: International Journal for Parasitology. 39, 6, p. 655-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sequential, ordered acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 domains
Cham, G. K. K., Turner, Louise, Lusingu, J., Vestergaard, L., Mmbando, B. P., Kurtis, J. D., Jensen, Anja Ramstedt, Salanti, Ali, Lavstsen, Thomas & Theander, Thor Grundtvig, 2009, In: Journal of Immunology. 183, 5, p. 3356-63 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Plasmodium falciparum var gene transcription strategy at the onset of blood stage infection in a human volunteer
Wang, Christian William, Hermsen, C. C., Sauerwein, R. W., Arnot, D. E., Theander, Thor Grundtvig & Lavstsen, Thomas, 2009, In: Parasitology International. 58, 4, p. 478-80 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Plasmodium falciparum transcriptome analysis reveals pregnancy malaria associated gene expression
Tuikue Ndam, N., Bischoff, E., Proux, C., Lavstsen, Thomas, Salanti, Ali, Guitard, J., Nielsen, Morten Agertoug, Coppée, J., Gaye, A., Theander, Thor Grundtvig, David, P. H. & Deloron, P., 2008, In: PLoS ONE. 3, 3, p. e1855Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A method for visualizing surface-exposed and internal PfEMP1 adhesion antigens in Plasmodium falciparum infected erythrocytes
Bengtsson, D., Sowa, K. M., Salanti, Ali, Jensen, Anja Ramstedt, Joergensen, L., Turner, Louise, Theander, Thor Grundtvig & Arnot, D. E., 2008, In: Malaria Journal. 7, p. 101Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A semi-automated multiplex high-throughput assay for measuring IgG antibodies against Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) domains in small volumes of plasma
Cham, G. K. K., Kurtis, J., Lusingu, J., Theander, Thor Grundtvig, Jensen, Anja Ramstedt & Turner, Louise, 2008, In: Malaria Journal. 7, p. 108Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biological and haematological safety profile of oral amodiaquine and chloroquine in healthy volunteers with or without Plasmodium falciparum infection in northeast Tanzania
Massaga, J. J., Lusingu, J. P., Makunde, R., Malebo, H. M., Chile, M. M., Akida, J. A., Lemnge, M. M., Rønn, A. M., Theander, Thor Grundtvig, Bygbjerg, Ib Christian & Kitua, A. Y., 2008, In: Tanzania Health Research Bulletin. 10, 3, p. 144-50 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CD36 selection of 3D7 Plasmodium falciparum associated with severe childhood malaria results in reduced VAR4 expression
Magistrado, P., Staalsoe, T., Theander, Thor Grundtvig, Hviid, Lars & Jensen, Anja Ramstedt, 2008, In: Malaria Journal. 7, 1, p. 204Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differences in human antibody reactivity to Plasmodium falciparum variant surface antigens are dependent on age and malaria transmission intensity in northeastern Tanzania
Vestergaard, L. S., Lusingu, J. P., Nielsen, Morten Agertoug, Mmbando, B. P., Dodoo, D., Akanmori, B. D., Alifrangis, Michael, Bygbjerg, Ib Christian, Lemnge, M. M., Staalsoe, T., Hviid, Lars & Theander, Thor Grundtvig, 2008, In: Infection and Immunity. 76, 6, p. 2706-14 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of glycosaminoglycan binding regions in the Plasmodium falciparum encoded placental sequestration ligand, VAR2CSA
Resende, M., Nielsen, Morten Agertoug, Dahlbäck, M., Ditlev, S. B., Andersen, P., Sander, A. F., Ndam, N. T., Theander, Thor Grundtvig & Salanti, Ali, 2008, In: Malaria Journal. 7, p. 104Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Parasitologi
Theander, Thor Grundtvig & Kurtzhals, Jørgen, 2008, Klinisk Mikrobiologi og Infektionsmedicin. Høiby, N. & Skinhøj, P. (eds.). København: FADL's Forlag, Vol. 11. p. 481-537 56 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Prospects and challenges regarding Plasmodium falciparum erythrocyte membrane protein I as vaccine antigens
Theander, Thor Grundtvig, 2008, In: International Journal for Parasitology. 38, Suppl. 1, p. S23-S23Research output: Contribution to journal › Journal article › Research
- Published
Reduced risk of uncomplicated malaria episodes in children with a+-thalassemia in northeastern Tanzania
Enevold, A., Lusingu, J. P., Mmbando, B., Alifrangis, Michael, Lemnge, M. M., Bygbjerg, Ib Christian, Theander, Thor Grundtvig & Vestergaard, L. S., 2008, In: American Journal of Tropical Medicine and Hygiene. 78, 5, p. 714-20 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Risk factors for low birth-weight in areas with varying malaria transmission in Korogwe, Tanzania: implications for malaria control
Mmbando, B. P., Cole-Lewis, H., Sembuche, S., Kamugisha, M. L., Theander, Thor Grundtvig, Lusingu, J. P. A. & Lemnge, M. M., 2008, In: Tanzania Health Research Bulletin. 10, 3, p. 137-43 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural insight into epitopes in the pregnancy-associated malaria protein VAR2CSA
Andersen, P., Nielsen, Morten Agertoug, Resende, M., Rask, T. S., Dahlbäck, M., Theander, Thor Grundtvig, Lund, O. & Salanti, Ali, 2008, In: PLoS Pathogens. 4, 2, p. e42Research output: Contribution to journal › Journal article › Research › peer-review
- Published
VAR2CSA expression on the surface of placenta-derived Plasmodium falciparum-infected erythrocytes
Magistrado, P., Salanti, Ali, Tuikue Ndam, N. G., Mwakalinga, S. B., Resende, M., Dahlbäck, M., Hviid, Lars, Lusingu, J., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2008, In: Journal of Infectious Diseases.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
3D7-derived Plasmodium falciparum erythrocyte membrane protein 1 is a frequent target of naturally acquired antibodies recognizing protein domains in a particular pattern independent of malaria transmission intensity
Joergensen, L., Vestergaard, L. S., Turner, Louise, Magistrado, P., Lusingu, J. P., Lemnge, M., Theander, Thor Grundtvig & Jensen, Anja Ramstedt, 2007, In: Journal of Immunology. 178, 1, p. 428-35 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasmodium falciparum: VAR2CSA expressed during pregnancy-associated malaria is partially resistant to proteolytic cleavage by trypsin
Nielsen, Morten Agertoug, Resende, M., Alifrangis, Michael, Turner, Louise, Hviid, Lars, Theander, Thor Grundtvig & Salanti, Ali, 2007, In: Experimental Parasitology. 117, 1, p. 1-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in var gene mRNA levels during erythrocytic development in two phenotypically distinct Plasmodium falciparum parasites
Dahlbäck, M., Lavstsen, Thomas, Salanti, Ali, Hviid, Lars, Arnot, D. E., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2007, In: Malaria Journal. 6, p. 78Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Developing Plasmodium falciparum malaria vaccines for populations living in areas with stable parasite transmission
Hviid, Lars & Theander, Thor Grundtvig, 2007, In: International Journal of Biotechnology. 9, 3/4, p. 292-300 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA
Barfod, Lea Klingenberg, Bernasconi, N. L., Dahlbäck, M., Jarrossay, D., Andersen, P. H., Salanti, Ali, Ofori, M. F., Turner, Louise, Resende, M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sallusto, F., Lanzavecchia, A. & Hviid, Lars, 2007, In: Molecular Microbiology. 63, 2, p. 335-47 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunoglobulin G antibody reactivity to a group A Plasmodium falciparum erythrocyte membrane protein 1 and protection from P. falciparum malaria
Magistrado, P. A., Lusingu, J., Vestergaard, L. S., Lemnge, M., Lavstsen, Thomas, Turner, Louise, Hviid, Lars, Jensen, Anja Ramstedt & Theander, Thor Grundtvig, 2007, In: Infection and Immunity. 75, 5, p. 2415-20 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Potential impact of host immunity on malaria treatment outcome in Tanzanian children infected with Plasmodium falciparum
Enevold, A., Nkya, W. M. M. M., Theisen, M., Vestergaard, L. S., Jensen, Anja Ramstedt, Staalsoe, T., Theander, Thor Grundtvig, Bygbjerg, Ib Christian & Alifrangis, Michael, 2007, In: Malaria Journal. 6, p. 153Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Baculovirus-expressed constructs induce immunoglobulin G that recognizes VAR2CSA on Plasmodium falciparum-infected erythrocytes
Barfod, Lea Klingenberg, Nielsen, Morten Agertoug, Turner, Louise, Dahlbäck, M., Jensen, Anja Ramstedt, Hviid, Lars, Theander, Thor Grundtvig & Salanti, Ali, 2006, In: Infection and Immunity. 74, 7, p. 4357-60 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Leishmania donovani: an in vitro study of antimony-resistant amphotericin B-sensitive isolates
Sharief, A. H., Gasim Khalil, E. A., Theander, Thor Grundtvig, Kharazmi, A., Omer, S. A. & Ibrahim, M. E., 2006, In: Experimental Parasitology. 114, 4, p. 247-52 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determinants of variant surface antigen antibody response in severe Plasmodium falciparum malaria in an area of low and unstable malaria transmission
A-Elgadir, T. M. E., Theander, Thor Grundtvig, Elghazali, G., Nielsen, Morten Agertoug, A-Elbasit, I. E., Adam, I., Troye-Blomberg, M., Elbashir, M. I. & Giha, H. A., 2006, In: Scandinavian Journal of Immunology. 63, 3, p. 232-40 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential expression of var gene groups is associated with morbidity caused by Plasmodium falciparum infection in Tanzanian children
Rottmann, M., Lavstsen, Thomas, Mugasa, J. P., Kaestli, M., Jensen, Anja Ramstedt, Müller, D., Theander, Thor Grundtvig & Beck, H., 2006, In: Infection and Immunity. 74, 7, p. 3904-11 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamics of anti-VAR2CSA immunoglobulin G response in a cohort of senegalese pregnant women
Tuikue Ndam, N. G., Salanti, Ali, Le-Hesran, J., Cottrell, G., Fievet, N., Turner, Louise, Sow, S., Dangou, J., Theander, Thor Grundtvig & Deloron, P., 2006, In: Journal of Infectious Diseases. 193, 5, p. 713-20 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epitope mapping and topographic analysis of VAR2CSA DBL3X involved in P. falciparum placental sequestration
Dahlbäck, M., Rask, T. S., Andersen, P. H., Nielsen, Morten Agertoug, Ndam, N. T., Resende, M., Turner, Louise, Deloron, P., Hviid, Lars, Lund, O., Pedersen, A. G., Theander, Thor Grundtvig & Salanti, Ali, 2006, In: PLoS Pathogens. 2, 11, p. e124Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Levels of plasma immunoglobulin G with specificity against the cysteine-rich interdomain regions of a semiconserved Plasmodium falciparum erythrocyte membrane protein 1, VAR4, predict protection against malarial anemia and febrile episodes
Lusingu, J. P. A., Jensen, Anja Ramstedt, Vestergaard, L. S., Minja, D. T., Dalgaard, M. B., Gesase, S., Mmbando, B. P., Kitua, A. Y., Lemnge, M. M., Cavanagh, D., Hviid, Lars & Theander, Thor Grundtvig, 2006, In: Infection and Immunity. 74, 5, p. 2867-75 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Limited cross-reactivity among domains of the Plasmodium falciparum clone 3D7 erythrocyte membrane protein 1 family
Joergensen, L., Turner, Louise, Magistrado, P., Dahlbäck, M. A., Vestergaard, L. S., Lusingu, J. P., Lemnge, M., Salanti, Ali, Theander, Thor Grundtvig & Jensen, Anja Ramstedt, 2006, In: Infection and Immunity. 74, 12, p. 6778-84 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Occurrence of the Southeast Asian/South American SVMNT haplotype of the chloroquine-resistance transporter gene in Plasmodium falciparum in Tanzania
Alifrangis, Michael, Dalgaard, M. B., Lusingu, J. P., Vestergaard, L. S., Staalsoe, T., Jensen, Anja Ramstedt, Enevold, A., Rønn, A. M., Khalil, I. F., Warhurst, D. C., Lemnge, M. M., Theander, Thor Grundtvig & Bygbjerg, Ib Christian, 2006, In: Journal of Infectious Diseases. 193, 12, p. 1738-41 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pathology of post-kala-azar dermal leishmaniasis: a light microscopical, immunohistochemical, and ultrastructural study of skin lesions and draining lymph nodes
Ismail, A., Gadir, A. F. A., Theander, Thor Grundtvig, Kharazmi, A. & El Hassan, A. M., 2006, In: Journal of Cutaneous Pathology. 33, 12, p. 778-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Programmed transcription of the var gene family, but not of stevor, in Plasmodium falciparum gametocytes
Sharp, S., Lavstsen, Thomas, Fivelman, Q. L., Saeed, M., McRobert, L., Templeton, T. J., Jensen, Anja Ramstedt, Baker, D. A., Theander, Thor Grundtvig & Sutherland, C. J., 2006, In: Eukaryotic Cell. 5, 8, p. 1206-14 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The pathogenesis of post kala-azar dermal leishmaniasis from the field to the molecule: does ultraviolet light (UVB) radiation play a role?
Ismail, A., Khalil, E. A. G., Musa, A. M., El Hassan, I. M., Ibrahim, M. E., Theander, Thor Grundtvig & El Hassan, A. M., 2006, In: Medical Hypotheses. 66, 5, p. 993-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
A simple, high-throughput method to detect Plasmodium falciparum single nucleotide polymorphisms in the dihydrofolate reductase, dihydropteroate synthase, and P. falciparum chloroquine resistance transporter genes using polymerase chain reaction- and enzyme-linked immunosorbent assay-based technology
Alifrangis, Michael, Enosse, S., Pearce, R., Drakeley, C., Roper, C., Khalil, I. F., Nkya, W. M., Rønn, A. M., Theander, Thor Grundtvig & Bygbjerg, Ib Christian, 2005, In: American Journal of Tropical Medicine and Hygiene. 72, 2, p. 155-62 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altitude-dependent and -independent variations in Plasmodium falciparum prevalence in northeastern Tanzania
Drakeley, C. J., Carneiro, I., Reyburn, H., Malima, R., Lusingu, J. P. A., Cox, J., Theander, Thor Grundtvig, Nkya, W. M. M. M., Lemnge, M. M. & Riley, E. M., 2005, In: Journal of Infectious Diseases. 191, 10, p. 1589-98 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical pattern of severe Plasmodium falciparum malaria in Sudan in an area characterized by seasonal and unstable malaria transmission
Giha, H. A., Elghazali, G., A-Elgadir, T. M. E., A-Elbasit, I. E., Eltahir, E. M., Baraka, O. Z., Khier, M. M., Adam, I., Troye-Blomberg, M., Theander, Thor Grundtvig & Elbashir, M. I., 2005, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 99, 4, p. 243-51 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cytophilic antibodies to Plasmodium falciparum glutamate rich protein are associated with malaria protection in an area of holoendemic transmission
Lusingu, J. P. A., Vestergaard, L. S., Alifrangis, Michael, Mmbando, B. P., Theisen, M., Kitua, A. Y., Lemnge, M. M. & Theander, Thor Grundtvig, 2005, In: Malaria Journal. 4, p. 48Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential induction of immunoglobulin G to Plasmodium falciparum variant surface antigens during the transmission season in Daraweesh, Sudan
Nielsen, Morten Agertoug, Grevstad, B., A-Elgadir, T. M. E., Kurtzhals, Jørgen, Giha, H., Staalsoe, T., Hviid, Lars & Theander, Thor Grundtvig, 2005, In: Journal of Infectious Diseases. 192, 3, p. 520-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of Plasmodium falciparum erythrocyte membrane protein 1 in experimentally infected humans
Lavstsen, Thomas, Magistrado, P., Hermsen, C. C., Salanti, Ali, Jensen, Anja Ramstedt, Sauerwein, R., Hviid, Lars, Theander, Thor Grundtvig & Staalsoe, T., 2005, In: Malaria Journal. 4, 1, p. 21Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High level of var2csa transcription by Plasmodium falciparum isolated from the placenta
Tuikue Ndam, N. G., Salanti, Ali, Bertin, G., Dahlbäck, M., Fievet, N., Turner, Louise, Gaye, A., Theander, Thor Grundtvig & Deloron, P., 2005, In: Journal of Infectious Diseases. 192, 2, p. 331-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid screening for glucose-6-phosphate dehydrogenase deficiency and haemoglobin polymorphisms in Africa by a simple high-throughput SSOP-ELISA method
Enevold, A., Vestergaard, L. S., Lusingu, J., Drakeley, C. J., Lemnge, M. M., Theander, Thor Grundtvig, Bygbjerg, Ib Christian & Alifrangis, Michael, 2005, In: Malaria Journal. 4, p. 61Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The roles of the pfcrt 76T and pfmdr1 86Y mutations, immunity and the initial level of parasitaemia, in predicting the outcome of chloroquine treatment in two areas with different transmission intensities
Khalil, I. F., Alifrangis, Michael, Tarimo, D. S., Staalsø, T., Satti, G. M. H., Theander, Thor Grundtvig, Rønn, A. M. & Bygbjerg, Ib Christian, 2005, In: Annals of Tropical Medicine and Parasitology. 99, 5, p. 441-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The use of nominal group technique in identifying community health priorities in Moshi rural district, northern Tanzania
Makundi, E. A., Manongi, R., Mushi, A. K., Alilio, M. S., Theander, Thor Grundtvig, Rønn, A. M. & Bygbjerg, Ib Christian, 2005, In: Tanzania Health Research Bulletin. 7, 3, p. 133-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of community owned resource persons (CORPs) in management of malaria in villages with different transmission intensity, North eastern Tanzania [MIM-BM-37562]
Mmbando, B., Lusingu, J., Vestergaard, L., Gesase, S., Minja, D., Minja, S., Malecela, E., Kitua, A., Lemnge, M. & Theander, Thor Grundtvig, 2005, In: Acta Tropica.Research output: Contribution to journal › Journal article › Research
- 2004
- Published
Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes
Jensen, Anja Ramstedt, Magistrado, P., Sharp, S., Joergensen, L., Lavstsen, Thomas, Chiucchiuini, A., Salanti, Ali, Vestergaard, L. S., Lusingu, J. P., Hermsen, R., Sauerwein, R., Christensen, J., Nielsen, Morten Agertoug, Hviid, Lars, Sutherland, C., Staalsoe, T. & Theander, Thor Grundtvig, 2004, In: Journal of Experimental Medicine. 199, 9, p. 1179-90 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibodies to the N-terminal block 2 of Plasmodium falciparum merozoite surface protein 1 are associated with protection against clinical malaria
Cavanagh, D. R., Dodoo, D., Hviid, Lars, Kurtzhals, Jørgen, Theander, Thor Grundtvig, Akanmori, B. D., Polley, S., Conway, D. J., Koram, K. & McBride, J. S., 2004, In: Infection and Immunity. 72, 11, p. 6492-502 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Compounds useful in the diagnosis and treatment of pregnancy-associated malaria
Theander, Thor Grundtvig, Salanti, Ali, Hviid, Lars, Staalsø, Trine, Jensen, Anja Ramstedt, Lavstsen, Thomas & Dahlbäck, M., 2004, Patent No. WO2004067559 A1, Priority date 27 Jan 2003, Priority No. WO2004067559 A1Research output: Patent
- Published
Eleven years of malaria surveillance in a Sudanese village highlights unexpected variation in individual disease susceptibility and outbreak severity
Creasey, A., Giha, H., Hamad, A. A., El Hassan, I. M., Theander, Thor Grundtvig & Arnot, D. E., 2004, In: Parasitology. 129, Pt 3, p. 263-71 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence for the involvement of VAR2CSA in pregnancy-associated malaria
Salanti, Ali, Dahlbäck, M., Turner, Louise, Nielsen, Morten Agertoug, Barfod, Lea Klingenberg, Magistrado, P., Jensen, Anja Ramstedt, Lavstsen, Thomas, Ofori, M. F., Marsh, K., Hviid, Lars & Theander, Thor Grundtvig, 2004, In: Journal of Experimental Medicine. 200, 9, p. 1197-203 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Geographical and temporal conservation of antibody recognition of Plasmodium falciparum variant surface antigens
Nielsen, Morten Agertoug, Vestergaard, L. S., Lusingu, J., Kurtzhals, Jørgen, Giha, H. A., Grevstad, B., Goka, B. Q., Lemnge, M. M., Jensen, J. B., Akanmori, B. D., Theander, Thor Grundtvig, Staalsoe, T. & Hviid, Lars, 2004, In: Infection and Immunity. 72, 6, p. 3531-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Malaria morbidity and immunity among residents of villages with different Plasmodium falciparum transmission intensity in North-Eastern Tanzania
Lusingu, J. P. A., Vestergaard, L. S., Mmbando, B. P., Drakeley, C. J., Jones, C., Akida, J., Savaeli, Z. X., Kitua, A. Y., Lemnge, M. M. & Theander, Thor Grundtvig, 2004, In: Malaria Journal. 3, p. 26Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
In vitro selection of Plasmodium falciparum 3D7 for expression of variant surface antigens associated with severe malaria in African children
Staalsoe, T., Nielsen, Morten Agertoug, Vestergaard, L. S., Jensen, Anja Ramstedt, Theander, Thor Grundtvig & Hviid, Lars, 2003, In: Parasite Immunology. 25, 8-9, p. 421-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of intermittent treatment with amodiaquine on anaemia and malarial fevers in infants in Tanzania: a randomised placebo-controlled trial
Massaga, J. J., Kitua, A. Y., Lemnge, M. M., Akida, J. A., Malle, L. N., Rønn, A. M., Theander, Thor Grundtvig & Bygbjerg, Ib Christian, 2003, In: Lancet. 361, 9372, p. 1853-60 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lack of gender-specific antibody recognition of products from domains of a var gene implicated in pregnancy-associated Plasmodium falciparum malaria
Jensen, Anja Ramstedt, Zornig, H. D., Buhmann, Cæcilie Christine Böck, Salanti, Ali, Koram, K. A., Riley, E. M., Theander, Thor Grundtvig, Hviid, Lars & Staalsoe, T., 2003, In: Infection and Immunity. 71, 7, p. 4193-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria
Salanti, Ali, Staalsoe, T., Lavstsen, Thomas, Jensen, Anja Ramstedt, Sowa, M. P. K., Arnot, D. E., Hviid, Lars & Theander, Thor Grundtvig, 2003, In: Molecular Microbiology. 49, 1, p. 179-91 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Specificity and cross-reactivity of Plasmodium falciparum variant surface antigen-specific antibody responses
Hviid, Lars, Staalsoe, T., Nielsen, Morten Agertoug & Theander, Thor Grundtvig, 2003, In: Infection and Immunity. 71, 4, p. 2296Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sub-grouping of Plasmodium falciparum 3D7 var genes based on sequence analysis of coding and non-coding regions
Lavstsen, Thomas, Salanti, Ali, Jensen, Anja Ramstedt, Arnot, D. E. & Theander, Thor Grundtvig, 2003, In: Malaria Journal. 2, p. 27Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
In vivo switching between variant surface antigens in human Plasmodium falciparum infection
Staalsoe, T., Hamad, A. A., Hviid, Lars, Elhassan, I. M., Arnot, D. E. & Theander, Thor Grundtvig, 2002, In: Journal of Infectious Diseases. 186, 5, p. 719-22 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasmodium falciparum variant surface antigen expression varies between isolates causing severe and nonsevere malaria and is modified by acquired immunity
Nielsen, Morten Agertoug, Staalsoe, T., Kurtzhals, Jørgen, Goka, B. Q., Dodoo, D., Alifrangis, Michael, Theander, Thor Grundtvig, Akanmori, B. D. & Hviid, Lars, 2002, In: Journal of Immunology. 168, 7, p. 3444-50 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A marked seasonality of malaria transmission in two rural sites in eastern Sudan
Hamad, A. A., Nugud, A. E. H. D., Arnot, D. E., Giha, H. A., Abdel-Muhsin, A. M. A., Satti, G. M. H., Theander, Thor Grundtvig, Creasey, A. M., Babiker, H. A. & Elnaiem, D. E. A., 2002, In: Acta Tropica. 83, 1, p. 71-82 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A sub-family of common and highly conserved Plasmodium falciparum var genes
Salanti, Ali, Jensen, Anja Ramstedt, Zornig, H. D., Staalsoe, T., Joergensen, L., Nielsen, Morten Agertoug, Khattab, A., Arnot, D. E., Klinkert, M. Q., Hviid, Lars & Theander, Thor Grundtvig, 2002, In: Molecular and Biochemical Parasitology. 122, 1, p. 111-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Humoral and cellular immune responses to glucose regulated protein 78 - a novel Leishmania donovani antigen
Jensen, Anja Ramstedt, Ismail, A., Gaafar, A., El Hassan, A. M. & Theander, Thor Grundtvig, 2002, In: Tropical Medicine & International Health. 7, 5, p. 471-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Malaria-induced acquisition of antibodies to Plasmodium falciparum variant surface antigens
Ofori, M. F., Dodoo, D., Staalsoe, T., Kurtzhals, Jørgen, Koram, K., Theander, Thor Grundtvig, Akanmori, B. D. & Hviid, Lars, 2002, In: Infection and Immunity. 70, 6, p. 2982-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel Plasmodium falciparum malaria vaccines: evidence-based searching for variant surface antigens as candidates for vaccination against pregnancy-associated malaria
Staalsoe, T., Jensen, Anja Ramstedt, Theander, Thor Grundtvig & Hviid, Lars, 2002, In: Immunology Letters. 84, 2, p. 133-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
- Published
Antibodies to variant antigens on the surfaces of infected erythrocytes are associated with protection from malaria in Ghanaian children
Dodoo, D., Staalsoe, T., Giha, H., Kurtzhals, Jørgen, Akanmori, B. D., Koram, K., Dunyo, S., Nkrumah, F. K., Hviid, Lars & Theander, Thor Grundtvig, 2001, In: Infection and Immunity. 69, 6, p. 3713-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cloning, expression and antigenicity of the L. donovani reductase
Jensen, Anja Ramstedt, Kemp, K., Theander, Thor Grundtvig & Handman, E., 2001, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 109, 6, p. 461-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential patterns of human immunoglobulin G subclass responses to distinct regions of a single protein, the merozoite surface protein 1 of Plasmodium falciparum
Cavanagh, D. R., Dobaño, C., Elhassan, I. M., Marsh, K., Elhassan, A., Hviid, Lars, Khalil, E. A., Theander, Thor Grundtvig, Arnot, D. E. & McBride, J. S., 2001, In: Infection and Immunity. 69, 2, p. 1207-11 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of fumarate reductase in Leishmania major and L. donovani by chalcones
Chen, M., Zhai, L., Christensen, Søren Brøgger, Theander, Thor Grundtvig & Kharazmi, A., 2001, In: Antimicrobial Agents and Chemotherapy. 45, 7, p. 2023-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 11256
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Real-time and label free determination of ligand binding-kinetics to primary cancer tissue specimens; a novel tool for the assessment of biomarker targeting
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Bacterial superglue enables easy development of efficient virus-like particle based vaccines
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Placental sequestration of Plasmodium falciparum malaria parasites is mediated by the interaction between VAR2CSA and chondroitin sulfate A on syndecan-1
Research output: Contribution to journal › Journal article › Research › peer-review
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