Lars Hviid
Professor
Centre for Medical Parasitology
CMP
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-11-TR4
Member of:
SURFACE team
I have been studying varying aspects of Plasmodium falciparum malaria, mainly the immunology, parasitology and pathogenesis of the disease, since 1985, and they continue to be my main research interests.
Current research
- Naturally acquired immunity to Plasmodium falciparum malaria in children and in pregnant women
- Effector functions of malaria antigen-specific antibodies
- The malaria-protective effect of certain hemoglobinopathies
- Malaria and endemic Burkitt Lymphoma
Fields of interest
- Naturally acquired immunity to P. falciparum malaria
- Immuno-evasion by P. falciparum parasites
- Enhancing malaria research capacity in Africa
Teaching
Regular teaching in immunology to undergraduate and graduate students at the Faculty of Health and Medical Sciences, University. Coordinator of the BSc course "Cellular and Medical Immunology".
Primary fields of research
- Immunology and pathogenesis of severe P. falciparum malaria in children.
- Immunology and pathogenesis of pregnancy-associated P. falciparum malaria.
- Immuno-evasive mechanisms and strategies of P. falciparum parasites.
My researcher profile at Google Scholar is here.
My researcher profile at ResearcherID is here.
Possible conflicts of interest
None.
Selected publications
- Published
Multiple Plasmodium falciparum erythrocyte membrane protein 1 variants per genome can bind IgM via its Fc fragment Fcμ
Jeppesen, A., Ditlev, S. B., Soroka, V., Stevenson, E. K., Turner, Louise, Dzikowski, R., Hviid, Lars & Barfod, Lea Klingenberg, 2015, In: Infection and Immunity. 83, 10, p. 3972-81 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigating the function of Fc -specific binding of IgM to Plasmodium falciparum erythrocyte membrane protein 1 mediating erythrocyte rosetting
Stevenson, L., Huda, P., Jeppesen, A., Laursen, E. T. F., Rowe, J. A., Craig, A., Streicher, W., Barfod, Lea Klingenberg & Hviid, Lars, Jun 2015, In: Cellular Microbiology. 17, 6, p. 819-31 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
α2-macroglobulin can crosslink multiple Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) molecules and may facilitate adhesion of parasitized erythrocytes
Stevenson, L., Laursen, E., Cowan, G. J., Bandoh, B., Barfod, Lea Klingenberg, Cavanagh, D. R., Andersen, G. R. & Hviid, Lars, Jul 2015, In: P L o S Pathogens. 11, 7, p. 1-19 19 p., e1005022.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evasion of immunity to Plasmodium falciparum malaria by IgM masking of protective IgG epitopes in infected erythrocyte surface-exposed PfEMP1
Barfod, Lea Klingenberg, Dalgaard, M. B., Pleman, S. T., Ofori, M. F., Pleass, R. J. & Hviid, Lars, 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 30, p. 12485-90 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetics of B Cell responses to Plasmodium falciparum erythrocyte membrane protein 1 in Ghanaian women naturally exposed to malaria parasites
Ampomah, P., Stevenson, L., Ofori, M. F., Barfod, Lea Klingenberg & Hviid, Lars, 1 Jun 2014, In: Journal of Immunology. 192, 11, p. 5236-44 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Selected activities
P L o S Medicine (Print) (Journal)
Hviid, Lars (Member of Editorial Board)
2006 → …Activity: Peer-review and editorial work types › Editor of Research journal › Research
ID: 3620
Most downloads
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3471
downloads
Kinetics of B Cell responses to Plasmodium falciparum erythrocyte membrane protein 1 in Ghanaian women naturally exposed to malaria parasites
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
2016
downloads
Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
2003
downloads
B-cell responses to pregnancy-restricted and -unrestricted Plasmodium falciparum erythrocyte membrane protein 1 antigens in Ghanaian women naturally exposed to malaria parasites
Research output: Contribution to journal › Journal article › Research › peer-review
Published