Knud Jørgen Jensen

Knud Jørgen Jensen

Professor


  1. Published

    3- instead of 4-helix formation in a de novo designed protein in solution revealed by small-angle X-ray scattering

    Høiberg-Nielsen, R., Shelton, A. P. T., Sørensen, K. K., Roessle, M., Svergun, D. I., Thulstrup, Peter Waaben, Jensen, Knud Jørgen & Arleth, Lise, 2008, In : ChemBioChem. 9, 16, p. 2663-2672 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    4,6-O-benzylidene directed ß-mannosylation without intermediate triflate formation? Comparison of trichloroacetimidate and DISAL donors in microwave-promoted glycosylations under neutral conditions

    Worm-Leonhard, K., Larsen, K. & Jensen, Knud Jørgen, 2007, In : Journal of Carbohydrate Chemistry. 26, 7, p. 349-368 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    De Novo design of proteins

    Jensen, Knud Jørgen, 2009, Peptide and protein design for biopharmaceutical applications. Jensen, K. J. (ed.). Wiley, p. 207-248 42 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  4. Published

    A 16.6 kDa disulfide-linked dimeric 4-helix bundle carboprotein: synthesis, CD spectroscopy, adsorption to AU(III) electrodes, and XPS and in situ STM studies

    Brask, J., Wackerbarth, H., Zhang, J., Andersen, J. E., Ulstrup, J. & Jensen, Knud Jørgen, 2002. 2 p.

    Research output: Contribution to conferencePaperResearch

  5. Published

    A brain-targeting lipidated peptide for neutralizing RNA-mediated toxicity in Polyglutamine Diseases

    Zhang, Q., Yang, M., Sørensen, K. K., Madsen, C. S., Boesen, J. T., An, Y., Peng, S. H., Wei, Y., Wang, Q., Jensen, Knud Jørgen, Zuo, Z., Chan, H. Y. E. & Ngo, J. C. K., 2017, In : Scientific Reports. 7, 1, 13 p., 12077.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility

    Zhao, B., Xu, P., Jiang, L., Jensen, B. P., Kromann-Hansen, T., Jensen, J. K., Sorensen, H. P., Liu, Z., Nielsen, J. T., Christensen, A., Hosseini, M., Sørensen, K. K., Nielsen, N. C., Jensen, Knud Jørgen, Huang, M. & Andreasen, P., 2014, In : PLOS ONE. 9, 12, 27 p., e115872.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A de novo designed monomeric, compact three helix bundle protein on a carbohydrate template

    Malik, L., Nygård, Jesper, Christensen, Niels Johan, Madsen, C. S., Rösner, Heike Ilona, Kragelund, Birthe Brandt, Høiberg-Nielsen, R., Streicher, W., Arleth, Lise, Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2015, In : ChemBioChem. 16, 13, p. 1905-1918 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    A high-throughput O-glycopeptide discovery platform for seromic profiling

    Blixt, Klas Ola, Cló, E., Nudelman, A. S., Sørensen, K. K., Clausen, T., Wandall, Hans H., Livingston, P. O., Clausen, Henrik & Jensen, Knud Jørgen, 2010, In : Journal of Proteome Research. 9, 10, p. 5250-5261 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    A highly acid-labile thiophene backbone amide linker: T-BAL

    Boas, U., Jessing, M., Christensen, J. B. & Jensen, Knud Jørgen, 2004, Ikke angivet. Michael Chorev, T. K. S. (ed.). American Peptide Society, p. 108-110 3 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  10. Published

    A plant chitinase controls cortical infection thread progression and nitrogen-fixing symbiosis

    Malolepszy, A., Kelly, S., Sørensen, K. K., James, E. K., Kalisch, C., Bozsoki, Z., Panting, M., Andersen, S. U., Sato, S., Tao, K., Jensen, D. B., Vinther, M., Jong, N. D., Madsen, L. H., Umehara, Y., Gysel, K., Berentsen, M. U., Blaise, M., Jensen, Knud Jørgen, Thygesen, Mikkel Boas, Sandal, N., Andersen, K. R. & Radutoiu, S., 2018, In : eLife. 7, p. 1-17 17 p., e38874.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A ¤16.6 kDa disulfide-linked dimeric 4-helix bundle carboprotein: synthesis, CD spectroscopy, adsorption to Au(III) electrodes, and XPS and in situ STM studies

    Brask, J., Wackerbarth, H., Zhang, J., Andersen, J. E., Ulstrup, J. & Jensen, Knud Jørgen, 2002. 2 p.

    Research output: Contribution to conferencePaperResearch

  12. Published

    Additional disulfide bonds in insulin: prediction, recombinant expression, receptor binding affinity, and stability

    Vinther, T. N., Pettersson, I., Huus, K., Schlein, M., Steensgaard, D. B., Sørensen, A., Jensen, Knud Jørgen, Kjeldsen, T. & Hubalek, F., 2015, In : Protein Science. 24, 5, p. 779-788 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    An intermolecular binding mechanism involving multiple LysM domains mediates carbohydrate recognition by an endopeptidase

    Wong, M. M. J. E., Midtgaard, S. R., Gysel, K., Thygesen, Mikkel Boas, Sørensen, K. K., Jensen, Knud Jørgen, Stougaard, J., Thirup, S. S. & Blaise, M., 2015, In : Acta Crystallographica. Section D: Biological Crystallography. 71, p. 592-605 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Antimicrobial peptide shows enhanced activity and reduced toxicity upon grafting to chitosan polymers

    Sahariah, P., Sørensen, K. K., Hjálmarsdóttir, M. Á., Sigurjónsson, Ó. E., Jensen, Knud Jørgen, Másson, M. & Thygesen, Mikkel Boas, 2015, In : Chemical Communications. 51, 58, p. 11611-11614 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Antisense Oligonucleotides Internally Labeled with Peptides Show Improved Target Recognition and Stability to Enzymatic Degradation

    Taskova, M., Madsen, C. S., Jensen, Knud Jørgen, Hansen, L. H., Vester, B. & Astakhova, K., 2017, In : Bioconjugate Chemistry. 28, 3, p. 768-774 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Automated 'X-Y' robot for peptide synthesis with microwave heating: application to difficult peptide sequences and protein domains

    Malik, L., Shelton, A. P. T., Pedersen, S. L., Sørensen, K. K. & Jensen, Knud Jørgen, 2010, In : Journal of Peptide Science. 16, 9, p. 506-512 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Automated microwave-assisted peptide synthesis with a novel robotic synthesizer: synthesis of difficult sequences

    Pedersen, S. L., Mehrotra, A. & Jensen, Knud Jørgen, 2010, Peptides - Copenhagen 2010, tales of peptides: proceedings of the thirty-first European peptide symposium, Copenhagen. Lebl, M., Meldal, M., Jensen, K. J. & Hoeg-Jensen, T. (eds.). European Peptide Society, p. 174-175 2 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  18. Published

    Backbone amide linker in solid-phase synthesis

    Boas, U., Brask, J. & Jensen, Knud Jørgen, 2009, In : Chemical Reviews. 109, 5, p. 2092-2118 27 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Backbone amide linker strategy: protocols for the synthesis of C-terminal peptide aldehydes

    Shelton, A. P. T. & Jensen, Knud Jørgen, 2013, Peptide synthesis and applications. Jensen, K. J., Shelton, P. T. & Pedersen, S. L. (eds.). Humana Press, p. 131-139 9 p. (Methods in Molecular Biology, Vol. 1047).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  20. Published

    Bicyclic peptide inhibitor of urokinase-type plasminogen activator: mode of action

    Roodbeen, R., Jensen, B. P., Jiang, L., Jensen, J. K., Christensen, A., Nielsen, J. T., Huang, M., Mulder, F., Nielsen, N. C., Andreasen, P. & Jensen, Knud Jørgen, 2013, In : ChemBioChem. 14, 16, p. 2179-2188 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. E-pub ahead of print

    Bioimaging and Biodistribution of the Metal‐Ion‐Controlled Self‐Assembly of PYY3–36 Studied by SPECT/CT

    Kalomoiri, Panagiota, Rodríguez‐rodríguez, C., Sørensen, K. K., Bergamo, M., Saatchi, K., Häfeli, Urs Otto & Jensen, Knud Jørgen, 2020, In : ChemBioChem. 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Bioorganisk og kombinatorisk kemi

    Jensen, Knud Jørgen & Nielsen, John, 2003, In : Dansk Kemi. 84, 2, p. 21-24 4 p.

    Research output: Contribution to journalJournal articleCommunication

  23. Published

    Brain-Targeting Delivery of Two Peptidylic Inhibitors for Their Combination Therapy in Transgenic Polyglutamine Disease Mice via Intranasal Administration

    Yang, M., Zhang, Q., Wang, Q., Sørensen, K. K., Boesen, Josephine Tuborg, Ma, S. Y., Jensen, Knud Jørgen, Kwan, K. M., Ngo, J. C. K., Chan, H. Y. E. & Zuo, Z., 2018, In : Molecular Pharmaceutics. 15, 12, p. 5781-5792 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    COMU: scope and limitations of the latest innovation in peptide acyl transfer reagents

    Subirós-Funosas, R., Nieto-Rodriguez, L., Jensen, Knud Jørgen & Albericio, F., 2013, In : Journal of Peptide Science. 19, 7, p. 408-414 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Carbohydrate-modified gold nanoparticles

    Thygesen, Mikkel Boas & Jensen, Knud Jørgen, 2016, Carbohydrate nanotechnology. J. Stine, K. (ed.). Wiley, p. 79-98

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  26. Published

    Carbohydrates as templates for control of distance-geometry in de novo-designed proteins

    Jensen, Knud Jørgen & Brask, J., 2002, In : Cellular and Molecular Life Sciences. 59, 5, p. 859-869 11 p.

    Research output: Contribution to journalJournal articleResearch

  27. Published

    Carbohydrates in peptide and protein design

    Jensen, Knud Jørgen & Brask, J., 2005, In : Biopolymers (Peptide Science). 80, 6, p. 747-761 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Carbohydrates in peptide and protein design

    Jensen, Knud Jørgen & Brask, J., 2009, Peptide and protein design for biopharmaceutical applications. Jensen, K. J. (ed.). Wiley, p. 177-206 30 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  29. Published

    Characterization of an immunodominant cancer-specific O-glycopeptide epitope in murine podoplanin (OTS8)

    Steentoft, Catharina, Schjoldager, Katrine Ter-Borch Gram, Cló, E., Mandel, Ulla, Levery, S. B., Pedersen, Johannes Wirenfeldt Vad, Jensen, Knud Jørgen, Blixt, Klas Ola & Clausen, Henrik, 2010, In : Glycoconjugate Journal. 27, 6, p. 571-82 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Characterization of the viral O-glycopeptidome: a novel tool of relevance for vaccine design and serodiagnosis

    Cló, E., Kracun, S. K., Nudelman, A. S., Jensen, Knud Jørgen, Liljeqvist, J., Olofsson, S., Bergström, T. & Blixt, Klas Ola, Jun 2012, In : Journal of Virology. 86, 11, p. 6268-78 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Chemical Strategies for Half-Life Extension of Biopharmaceuticals: Lipidation and Its Alternatives

    Bech, E. M., Pedersen, Søren Lhjungmann & Jensen, Knud Jørgen, 2018, In : ACS Medicinal Chemistry Letters. 9, 7, p. 577-580 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Chemically synthesized 58-mer LysM domain binds lipochitin oligosaccharide

    Sørensen, K. K., Simonsen, J. B., Maolanon, N. N., Stougaard, J. & Jensen, Knud Jørgen, 2014, In : ChemBioChem. 15, 14, p. 2097-2105 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Chemoselective Reactions for the Synthesis of Glycoconjugates from Unprotected Carbohydrates

    Villadsen, K., Martos Maldonado, M. C., Jensen, Knud Jørgen & Thygesen, Mikkel Boas, 2017, In : ChemBioChem. 18, 7, p. 574-612 39 p.

    Research output: Contribution to journalReviewResearchpeer-review

  34. Published

    Chemoselective capture of glycans for analysis on gold nanoparticles: carbohydrate oxime tautomers provide functional recognition by proteins

    Thygesen, Mikkel Boas, Sauer, J. & Jensen, Knud Jørgen, 2009, In : Chemistry: A European Journal. 15, 7, p. 1949-1960 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Chemoselective reagents for covalent capture and display of glycans in microarrays

    Cló, E., Blixt, Klas Ola & Jensen, Knud Jørgen, 2010, In : European Journal of Organic Chemistry. 2010, 3, p. 540-554 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Chemoselectivity and Glyconanoparticles

    Thygesen, Mikkel Boas & Jensen, Knud Jørgen, 2011, Petite and sweet: Glyco-nanotechnology as a bridge to new medicines. American Chemical Society, p. 37-48 12 p. (A C S Symposium Series, Vol. 1091).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  37. Published

    Combinatorial solid-phase synthesis of hapalosin mimetics

    Olsen, J. A., Jensen, Knud Jørgen & Nielsen, John, 1 Mar 2000, In : Journal of Combinatorial Chemistry. 2, 2, p. 143-150 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Computational Studies of the Stability and Chirality of Self-assembled Complexes of a Novel Iron(II)-binding Insulin Derivative

    Christensen, Niels Johan, Munch, H. K., Heide, S. T., Høeg-Jensen, T., Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2010, In : Journal of Peptide Science. S2

    Research output: Contribution to journalConference abstract in journalResearch

  39. Published

    Computational studies of the stability and chirality of self-assembled complexes of a novel iron(II)-binding insulin derivative

    Christensen, Niels Johan, Munch, H. K., Heide, S. T., Hoeg-Jensen, T., Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2010, Proceedings of the 31st European Peptide Symposium. Lebl, M., Meldal, M., Jensen, K. J. & Hoeg-Jensen, T. (eds.). European Peptide Society, p. 628-629 2 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  40. Published

    Construction of insulin 18-mer nanoassemblies driven by coordination to Iron(II) and Zinc(II) ions at distinct sites

    Munch, H. K., Nygård, Jesper, Christensen, Niels Johan, Engelbrekt, C., Østergaard, M., Porsgaard, T., Hoeg-Jensen, T., Zhang, J., Arleth, Lise, Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2016, In : Angewandte Chemie International Edition. 55, 7, p. 2378-2381 4 p.

    Research output: Contribution to journalLetterResearchpeer-review

  41. Published

    Controlled self-assembly of re-engineered insulin by FeII

    Munch, H. K., Heide, S. T., Christensen, Niels Johan, Høeg-Jensen, T., Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2011, In : Chemistry: A European Journal. 17, 26, p. 7198-7204 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Corrigendum to "End-to-end assembly of gold nanorods via oligopeptide linking and surfactant control" [J. Colloid Interface Sci. 376 (2012) 83-90]

    Jain, T., Roodbeen, R., Reeler, N. E. A., Vosch, Tom, Jensen, Knud Jørgen, Bjørnholm, T. & Nørgaard, K., 15 Oct 2012, In : Journal of Colloid and Interface Science. 384, 1, 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  43. Published

    DISAL glycosyl donors for the synthesis of a linear hexasaccharide under mild conditions

    Petersen, L., Laursen, J. B., Larsen, K., Motawie, Mohammed Saddik & Jensen, Knud Jørgen, 2003, In : Organic Letters. 5, 8, p. 1309-1312 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    De novo designed triple-helix bundle proteins on a carbohydrate template

    Malik, L., Nygaard, J., Høiberg-Nielsen, R., Christensen, Niels Johan, Thulstrup, Peter Waaben, Arleth, Lise & Jensen, Knud Jørgen, 2010, In : Journal of Peptide Science. S2

    Research output: Contribution to journalConference abstract in journalResearch

  45. Published

    Dimeric peptides with three different linkers self-assemble with phospholipids to form peptide nanodiscs that stabilize membrane proteins

    Larsen, A. N., Sørensen, K. K., Johansen, Nicolai Tidemand, Martel, A., Kirkensgaard, Jacob Judas Kain, Jensen, Knud Jørgen, Arleth, Lise & Midtgaard, S. R., 2016, In : Soft Matter. 12, 27, p. 5937-5949 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Direct chemoselective synthesis of glyconanoparticles from unprotected reducing glycans and glycopeptide aldehydes

    Thygesen, Mikkel Boas, Sørensen, K. K., Cló, E. & Jensen, Knud Jørgen, Nov 2009, In : Chemical Communications. 42, p. 6367-9 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Distinctive binding modes and inhibitory mechanisms of two peptidic inhibitors of urokinase-type plasminogen activator with isomeric P1 residues

    Jiang, L., Zhao, B., Xu, P., Sørensen, H. P., Jensen, J. K., Christensen, A., Hosseini, M., Nielsen, N. C., Jensen, Knud Jørgen, Andreasen, P. & Huang, M., 2015, In : International Journal of Biochemistry & Cell Biology. 62, p. 88-92 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  48. Published

    Effect of residual water and microwave heating on half-lifes of reagents and reactive intermediates in peptide synthesis

    Shelton, A. P. T., Pedersen, S. L., Stærk, Dan & Jensen, Knud Jørgen, 2012, In : Chemistry: A European Journal. 18, 29, p. 9024-9031 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Efficient synthesis of glycosylated phenazine natural products and analogs with DISAL (methyl 3,5-dinitrosalicylate) glycosyl donors

    Laursen, J. B., Petersen, L., Jensen, Knud Jørgen & Nielsen, John, 2003, In : Organic and Biomolecular Chemistry. 1, 18, p. 3147-3153 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Elucidation of the contribution of active site and exosite interactions to affinity and specificity of peptidylic serine protease inhibitors, using non-natural arginine analogues

    Hosseini, M., Jiang, L., Sørensen, H. P., Jensen, J. K., Christensen, A., Fogh, S., Yuan, C., Andersen, L. M., Huang, M., Andreasen, P. & Jensen, Knud Jørgen, 2011, In : Molecular Pharmacology. 80, 4, p. 585-597 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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