Hiren Jitendra Joshi

Hiren Jitendra Joshi

Associate Professor

ORCID: 0000-0002-8192-2829

Publication year:
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1 - 46 out of 46Page size: 100
  1. 2024
  2. Published

    A family of di-glutamate mucin-degrading enzymes that bridges glycan hydrolases and peptidases

    Narimatsu, Yoshiki, Büll, C., Taleb, V., Liao, Q., Compañón, I., Sánchez-Navarro, D., Durbesson, F., Vincentelli, R., Hansen, Lars, Corzana, F., Rovira, C., Henrissat, B., Clausen, Henrik, Joshi, Hiren Jitendra & Hurtado-Guerrero, R., 2024, In: Nature Catalysis. 7, p. 386–400 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Molecular-level architecture of Chlamydomonas reinhardtii’s glycoprotein-rich cell wall

    Poulhazan, A., Arnold, A. A., Mentink-Vigier, F., Muszyński, A., Azadi, P., Halim, Adnan, Vakhrushev, Sergey, Joshi, Hiren Jitendra, Wang, T., Warschawski, D. E. & Marcotte, I., 2024, In: Nature Communications. 15, 1, 15 p., 986.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. 2023
  5. Published

    The SHDRA syndrome-associated gene TMEM260 encodes a protein-specific O-mannosyltransferase

    Larsen, I. S. B., Povolo, Lorenzo, Zhou, L., Tian, W., Mygind, Kasper Johansen, Hintze, John, Jiang, C., Hartill, V., Prescott, K., Johnson, C. A., Mullegama, S. V., McConkie-Rosell, A., McDonald, M., Hansen, Lars, Vakhrushev, Sergey, Schjoldager, Katrine Ter-Borch Gram, Clausen, Henrik, Worzfeld, T., Joshi, Hiren Jitendra & Halim, Adnan, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 21, p. e2302584120

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2022
  7. Published

    Applying transcriptomics to studyglycosylation at the cell type level

    Dworkin, L. A., Clausen, Henrik & Joshi, Hiren Jitendra, 2022, In: iScience. 25, 6, 104419.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 2021
  9. Published

    Display of the human mucinome with defined O-glycans by gene engineered cells

    Nason, R., Büll, C., Konstantinidi, A., Sun, L., Ye, Z., Halim, A., Du, W., Sørensen, D. M., Durbesson, F., Furukawa, S., Mandel, U., Joshi, H. J., Dworkin, L. A., Hansen, L., David, L., Iverson, T. M., Bensing, B. A., Sullam, P. M., Varki, A., Vries, E. D. & 6 others, de Haan, C. A. M., Vincentelli, R., Henrissat, B., Vakhrushev, Sergey, Clausen, Henrik & Narimatsu, Yoshiki, 2021, In: Nature Communications. 12, 1, 16 p., 4070.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. 2020
  11. Published

    An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles

    Madsen, Thomas Daugbjerg, Hansen, L. H., Hintze, John, Ye, Z., Jebari, S., Andersen, Daniel Bjørklund, Joshi, Hiren Jitendra, Ju, T., Goetze, Jens P. , Martin, C., Rosenkilde, Mette, Holst, Jens Juul, Kuhre, Rune Ehrenreich, Goth, C. K., Vakhrushev, Sergey & Schjoldager, Katrine Ter-Borch Gram, 2020, In: Nature Communications. 11, 1, 13 p., 4033.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Cell-Based Glycan Arrays — A Practical Guide to Dissect the Human Glycome

    Büll, C., Joshi, Hiren Jitendra, Clausen, Henrik & Narimatsu, Yoshiki, 2020, In: STAR Protocols. 1, 1, 100017.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Global view of human protein glycosylation pathways and functions

    Schjoldager, Katrine Ter-Borch Gram, Narimatsu, Yoshiki, Joshi, Hiren Jitendra & Clausen, Henrik, 2020, In: Nature Reviews Molecular Cell Biology. 21, p. 729–749

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    O-glycan initiation directs distinct biological pathways and controls epithelial differentiation

    Bagdonaite, Ieva , Pallesen, E. M. H., Ye, Z., Vakhrushev, Sergey, Marinova, I. N., Nielsen, Mathias Alexander Ingemann, Kramer, S. H., Pedersen, Stine Helene Falsig, Joshi, Hiren Jitendra, Bennett, Eric Paul, Dabelsteen, Sally & Wandall, Hans H., 2020, In: EMBO Reports. 21, 6, 17 p., e48885.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Structural characterization of an unprecedented lectin-like antitumoral anti-MUC1 antibody

    Macías-León, J., Bermejo, I. A., Asín, A., García-García, A., Compañón, I., Jiménez-Moreno, E., Coelho, H., Mangini, V., Albuquerque, I. S., Marcelo, F., Asensio, J. L., Bernardes, G. J. L., Joshi, Hiren Jitendra, Fiammengo, R., Blixt, O., Hurtado-Guerrero, R. & Corzana, F., 2020, In: Chemical communications (Cambridge, England). 56, 96, p. 15137-15140 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2019
  17. Published

    A strategy for generating cancer-specific monoclonal antibodies to aberrant O-glycoproteins: identification of a novel dysadherin-Tn antibody

    Steentoft, C., Fuhrmann, M., Battisti, F., Van Coillie, Julie, Madsen, Thomas Daugbjerg, Campos, D., Halim, Adnan, Vakhrushev, Sergey, Joshi, Hiren Jitendra, Schreiber, H., Mandel, Ulla & Narimatsu, Yoshiki, 2019, In: Glycobiology. 29, 4, p. 307-319 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    An Atlas of Human Glycosylation Pathways Enables Display of the Human Glycome by Gene Engineered Cells

    Narimatsu, Y., Joshi, H. J., Nason, R., Van Coillie, J., Karlsson, R., Sun, L., Ye, Z., Chen, Y-H., Schjoldager, K. T., Steentoft, C., Furukawa, S., Bensing, B. A., Sullam, P. M., Thompson, A. J., Paulson, J. C., Büll, C., Adema, G. J., Mandel, U., Hansen, L., Bennett, E. P. & 4 others, Varki, A., Vakhrushev, Sergey, Yang, Zhang & Clausen, Henrik, 2019, In: Molecular Cell. 75, 2, p. 394-407, e1-e5

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Exploring Regulation of Protein O-Glycosylation in Isogenic Human HEK293 Cells by Differential O-Glycoproteomics

    Narimatsu, Yoshiki, Joshi, Hiren Jitendra, Schjoldager, Katrine Ter-Borch Gram, Hintze, John, Halim, Adnan, Steentoft, C., Nason, R., Mandel, Ulla, Bennett, Eric Paul, Clausen, Henrik & Vakhrushev, Sergey, 2019, In: Molecular and Cellular Proteomics. 18, 7, p. 1396-1409

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Multiple distinct O-Mannosylation pathways in eukaryotes

    Larsen, I. S. B., Narimatsu, Yoshiki, Clausen, Henrik, Joshi, Hiren Jitendra & Halim, Adnan, 2019, In: Current Opinion in Structural Biology. 56, p. 171-178 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  21. 2018
  22. Published

    Viral glycoproteomes: Technologies for characterization and outlook for vaccine design

    Bagdonaite, Ieva , Vakhrushev, Sergey, Joshi, Hiren Jitendra & Wandall, Hans H., Dec 2018, In: FEBS Letters. 592, 23, p. 3898-3920

    Research output: Contribution to journal › Review › Research › peer-review

  23. Published

    GlycoDomainViewer: A bioinformatics tool for contextual exploration of glycoproteomes

    Joshi, Hiren Jitendra, Jørgensen, A., Schjoldager, Katrine Ter-Borch Gram, Halim, Adnan, Dworkin, L. A., Steentoft, C., Wandall, Hans H., Clausen, Henrik & Vakhrushev, Sergey, 1 Mar 2018, In: Glycobiology. 28, 3, p. 131-136 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    SnapShot: O-Glycosylation Pathways across Kingdoms

    Joshi, Hiren Jitendra, Narimatsu, Yoshiki, Schjoldager, Katrine Ter-Borch Gram, Tytgat, H. L. P., Aebi, M., Clausen, Henrik & Halim, Adnan, Jan 2018, In: Cell. 172, 3, p. 632–632.e2

    Research output: Contribution to journal › Review › Research › peer-review

  25. Published

    A validated gRNA library for CRISPR/Cas9 targeting of the human glycosyltransferase genome

    Narimatsu, Yoshiki, Joshi, Hiren Jitendra, Zhang, Y., Gomes, C., Chen, Yen-Hsi, Lorenzetti, F., Furukawa, S., Schjoldager, Katrine Ter-Borch Gram, Hansen, Lars, Clausen, Henrik, Bennett, Eric Paul & Wandall, Hans H., 2018, In: Glycobiology. 28, 5, p. 295–305

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Fine-Tuning Limited Proteolysis: A Major Role for Regulated Site-Specific O-Glycosylation

    Goth, C. K., Vakhrushev, Sergey, Joshi, Hiren Jitendra, Clausen, Henrik & Schjoldager, Katrine Ter-Borch Gram, 2018, In: Trends in Biochemical Sciences. 43, 4, p. 269-284 16 p.

    Research output: Contribution to journal › Review › Research › peer-review

  27. Published

    Glycosyltransferase genes that cause monogenic congenital disorders of glycosylation are distinct from glycosyltransferase genes associated with complex diseases

    Joshi, Hiren Jitendra, Hansen, Lars, Narimatsu, Yoshiki, Freeze, H. H., Henrissat, B., Bennett, Eric Paul, Wandall, Hans H., Clausen, Henrik & Schjoldager, Katrine Ter-Borch Gram, 2018, In: Glycobiology. 28, 5, p. 284-294

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Probing the contribution of individual polypeptide GalNAc-transferase isoforms to the O-glycoproteome by inducible expression in isogenic cell lines

    Hintze, John, Ye, Z., Narimatsu, Yoshiki, Madsen, Thomas Daugbjerg, Joshi, Hiren Jitendra, Goth, C. K., Linstedt, A., Bachert, C., Mandel, Ulla, Bennett, Eric Paul, Vakhrushev, Sergey & Schjoldager, Katrine Ter-Borch Gram, 2018, In: The Journal of Biological Chemistry. 293, 49, p. 19064-19077 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    TAILS N-Terminomics and proteomics reveal complex regulation of proteolytic cleavage by O-glycosylation

    King, S. L., Goth, C. K., Eckhard, U., Joshi, Hiren Jitendra, Haue, Amalie Dahl, Vakhrushev, Sergey, Schjoldager, Katrine Ter-Borch Gram, Overall, C. M. & Wandall, Hans H., 2018, In: The Journal of Biological Chemistry. 293, 20, p. 7629-7644 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. 2017
  31. Published

    Mapping sites and molecular functions of O-glycosylation

    Schjoldager, Katrine Ter-Borch Gram, Wang, S., Joshi, Hiren Jitendra, Mao, Y. & Vakhrushev, Sergey, Dec 2017, In: Glycobiology. 27, 12, p. 1189-1189 47.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  32. Published

    Characterizing the O-glycosylation landscape of human plasma, platelets, and endothelial cells

    King-Smith, S. L., Joshi, Hiren Jitendra, Schjoldager, Katrine Ter-Borch Gram, Halim, Adnan, Madsen, Thomas Daugbjerg, Dziegiel, Morten Hanefeld, Woetmann, Anders , Vakhrushev, Sergey & Wandall, Hans H., 2017, In: Blood advances. 1, 7, p. 429-442 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Discovery of an O-mannosylation pathway selectively serving cadherins and protocadherins

    Larsen, I. S. B., Narimatsu, Yoshiki, Joshi, Hiren Jitendra, Siukstaite, L., Harrison, O. J., Brasch, J., Goodman, K. M., Hansen, Lars, Shapiro, L., Honig, B., Vakhrushev, Sergey, Clausen, Henrik & Halim, Adnan, 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 42, p. 11163-11168 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Isoform-specific mucin type O-glycosylation maintain epithelial homeostasis

    Bagdonaite, Ieva , E.M.H., P., K., L., Vakhrushev, Sergey, Hansen, Lars, Joshi, Hiren Jitendra, Bennett, Eric Paul, Dabelsteen, Sally & Wandall, Hans H., 2017, In: Glycoconjugate Journal. 34, Suppl. 1, p. S42 1 p., Abstract 78.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  35. Published

    Mammalian O-mannosylation of Cadherins and Plexins is Independent of Protein O-mannosyltransferase 1 and 2

    Larsen, I. S. B., Narimatsu, Yoshiki, Joshi, Hiren Jitendra, Yang, Zhang, Harrison, O. J., Brasch, J., Shapiro, L., Honig, B., Vakhrushev, Sergey, Clausen, Henrik & Halim, Adnan, 2017, In: The Journal of Biological Chemistry. 292, p. 11586-11598

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. 2016
  37. Published

    Global Mapping of O-Glycosylation of Human Herpesviruses

    Bagdonaite, Ieva , Norden, R., Joshi, Hiren Jitendra, King-Smith, S. L., Vakhrushev, Sergey, Olofsson, S. & Wandall, Hans H., Dec 2016, In: Glycobiology. 26, 12, p. 1408-1408

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  38. Published

    Regulation of protein O-glycosylation in epithelial cells - the polypeptide GalNAc-transferases direct cellular differentiation and maintenance of tissue homeostasis

    Pallesen, E. M., Bagdonaite, Ieva , Vakhrushev, Sergey, Hansen, Lars, Joshi, Hiren Jitendra, Dabelsteen, Sally & Wandall, Hans H., Dec 2016, In: Glycobiology. 26, 12, p. 1391-1391

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  39. Published

    Global Mapping of O-Glycosylation of Varicella Zoster Virus, Human Cytomegalovirus, and Epstein-Barr Virus

    Bagdonaite, Ieva , Nordén, R., Joshi, Hiren Jitendra, King-Smith, S. L., Vakhrushev, Sergey, Olofsson, S. & Wandall, Hans H., 3 Jun 2016, In: The Journal of Biological Chemistry. 291, 23, p. 12014-12028 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Mapping the O-Mannose Glycoproteome in Saccharomyces cerevisiae

    Neubert, P., Halim, Adnan, Zauser, M., Essig, A., Joshi, Hiren Jitendra, Zatorska, E., Larsen, I. S. B., Loibl, M., Castells-Ballester, J., Aebi, M., Clausen, Henrik & Strahl, S., Apr 2016, In: Molecular and Cellular Proteomics. 15, 4, p. 1323-37 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. 2015
  42. Published

    Deconstruction of O-glycosylation-GalNAc-T isoforms direct distinct subsets of the O-glycoproteome

    Schjoldager, Katrine Ter-Borch Gram, Joshi, Hiren Jitendra, Kong, Y., Goth, C. K., King-Smith, S. L., Wandall, Hans H., Bennett, Eric Paul, Vakhrushev, Sergey & Clausen, Henrik, Dec 2015, In: E M B O Reports. 16, 12, p. 1713-22 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    A Strategy for O-Glycoproteomics of Enveloped Viruses-the O-Glycoproteome of Herpes Simplex Virus Type 1

    Bagdonaite, Ieva , Nordén, R., Joshi, Hiren Jitendra, Dabelsteen, Sally, Nyström, K., Vakhrushev, Sergey, Olofsson, S. & Wandall, Hans H., 1 Apr 2015, In: P L o S Pathogens. 11, 4, p. 1-22 22 p., e1004784.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Protein O-Galnac Glycosylation: Most Complex and Differentially Regulated PTM

    Joshi, Hiren Jitendra, Steentoft, C., Schjoldager, Katrine Ter-Borch Gram, Vakhrushev, Sergey, Wandall, Hans H. & Clausen, Henrik, 1 Jan 2015, Glycoscience: Biology and Medicine. Springer, p. 1049-1064 16 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  45. Published

    Probing polypeptide GalNAc-transferase isoform substrate specificities by in vitro analysis

    Kong, Y., Joshi, Hiren Jitendra, Schjoldager, Katrine Ter-Borch Gram, Madsen, Thomas Daugbjerg, Gerken, T. A., Vester-Christensen, M. B., Wandall, Hans H., Bennett, Eric Paul, Levery, S. B., Vakhrushev, Sergey & Clausen, Henrik, Jan 2015, In: Glycobiology. 25, 1, p. 55-65 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    A glycogene mutation map for discovery of diseases of glycosylation

    Hansen, Lars, Lind-Thomsen, A., Joshi, Hiren Jitendra, Pedersen, N. B., Have, C. T., Kong, Y., Wang, S., Sparso, T., Grarup, Niels, Vester-Christensen, M. B., Schjoldager, Katrine Ter-Borch Gram, Freeze, H. H., Hansen, Torben, Pedersen, Oluf Borbye, Henrissat, B., Mandel, Ulla, Clausen, Henrik, Wandall, Hans H. & Bennett, Eric Paul, 2015, In: Glycobiology. 25, 2, p. 211-224 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Discovery of a nucleocytoplasmic O-mannose glycoproteome in yeast

    Halim, Adnan, Larsen, I. S. B., Neubert, P., Joshi, Hiren Jitendra, Petersen, Bent L, Vakhrushev, Sergey, Strahl, S. & Clausen, Henrik, 2015, In: Glycobiology. 25, 11, p. 1235 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  48. Published

    Discovery of a nucleocytoplasmic O-mannose glycoproteome in yeast

    Halim, Adnan, Larsen, I. S. B., Neubert, P., Joshi, Hiren Jitendra, Petersen, Bent L, Vakhrushev, Sergey, Strahl, S. & Clausen, Henrik, 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 51, p. 15648-15653 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Eukaryotic glycosylation: online methods for site prediction on protein sequences

    Joshi, Hiren Jitendra & Gupta, R., 2015, Glycoinformatics : Methods in Molecular Biology . Lütteke, T. & Frank, M. (eds.). New York: Springer Science+Business Media, Vol. 1273. p. 127-37 11 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  50. 2014
  51. Published

    The GalNAc-type O-glycoproteome of CHO cells characterized by the SimpleCell strategy

    Yang, Zhang, Halim, Adnan, Narimatsu, Yoshiki, Joshi, Hiren Jitendra, Steentoft, C., Schjoldager, Katrine Ter-Borch Gram, Schulz, M. A., Sealover, N. R., Kayser, K. J., Bennett, Eric Paul, Levery, S. B., Vakhrushev, Sergey & Clausen, Henrik, Dec 2014, In: Molecular & Cellular Proteomics. 13, 12, p. 3224-3235 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. 2013
  53. Published

    Mining the O-mannose glycoproteome reveals cadherins as major O-mannosylated glycoproteins

    Vester-Christensen, M. B., Halim, Adnan, Joshi, Hiren Jitendra, Steentoft, C., Bennett, Eric Paul, Levery, S. B., Vakhrushev, Sergey & Clausen, Henrik, 24 Dec 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 52, p. 21018-23 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    MASCP gator: An overview of the arabidopsis proteomic aggregation portal

    Mann, G. W., Calley, P. C., Joshi, Hiren Jitendra & Heazlewood, J. L., 23 Oct 2013, In: Frontiers in Plant Science. 4, 411.

    Research output: Contribution to journal › Review › Research › peer-review

  55. Published

    Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology

    Steentoft, C., Vakhrushev, Sergey, Joshi, Hiren Jitendra, Kong, Y., Vester-Christensen, M. B., Schjoldager, Katrine Ter-Borch Gram, Lavrsen, K., Dabelsteen, Sally, Pedersen, N. B., da Silva, L. P. M., Gupta, R., Bennett, Eric Paul, Mandel, Ulla, Brunak, Søren, Wandall, Hans H., Levery, S. B. & Clausen, Henrik, 15 May 2013, In: E M B O Journal. 32, 10, p. 1478-1488 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. 2010

  57. GlycoViewer: A tool for visual summary and comparative analysis of the glycome

    Joshi, Hiren Jitendra, von der Lieth, C. W., Packer, N. H. & Wilkins, M. R., 25 May 2010, In: Nucleic Acids Research. 38, SUPPL. 2, p. W667-W670 gkq446.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. 2004

  59. Development of a mass fingerprinting tool for automated interpretation of oligosaccharide fragmentation data

    Joshi, Hiren Jitendra, Harrison, M. J., Schulz, B. L., Cooper, C. A., Packer, N. H. & Karlsson, N. G., 1 Jun 2004, In: Proteomics. 4, 6, p. 1650-1664 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. 2003

  61. GlycoSuiteDB: A curated relational database of glycoprotein glycan structures and their biological sources. 2003 update

    Cooper, C. A., Joshi, Hiren Jitendra, Harrison, M. J., Wilkins, M. R. & Packer, N. H., 1 Jan 2003, In: Nucleic Acids Research. 31, 1, p. 511-513 3 p.

    Research output: Contribution to journal › Review › Research › peer-review

ID: 37678357