Hans Bräuner

Characterization of the real-time internalization of nine GPCRs reveals distinct dependence on arrestins and G proteins

Møller, T. C., Moo, Ee Von, Inoue, A., Pedersen, M. F. & Bräuner, Hans, 2024, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1871, 1, 12 p., 119584.

Research output: Contribution to journal › Journal article › Research › peer-review

Structure-Activity Relationship Studies and Optimization of 4-Hydroxypyridones as GPR84 Agonists

Ieremias, L., Kaspersen, M. H., Manandhar, Asmita, Schultz-Knudsen, Katrine, Vrettou, C. I., Pokhrel, R., Heidtmann, C. V., Jenkins, L., Kanellou, C., Marsango, S., Li, Y., Bräuner, Hans, Ulven, Elisabeth Rexen, Milligan, G. & Ulven, Trond, 2024, In: Journal of Medicinal Chemistry. 67, 5, p. 3542-3570

Research output: Contribution to journal › Journal article › Research › peer-review

The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

Alexander, S. P. H., Christopoulos, A., Davenport, A. P., Kelly, E., Mathie, A. A., Peters, J. A., Veale, E. L., Armstrong, J. F., Faccenda, E., Harding, S. D., Davies, J. A., Abbracchio, M. P., Abraham, G., Agoulnik, A., Alexander, W., Al-Hosaini, K., Bäck, M., Baker, J. G., Barnes, N. M., Bathgate, R. & 146 others, Beaulieu, J., Beck-Sickinger, A. G., Behrens, M., Bernstein, K. E., Bettler, B., Birdsall, N. J. M., Blaho, V., Boulay, F., Bousquet, C., Bräuner, Hans, Burnstock, G., Caló, G., Castaño, J. P., Catt, K. J., Ceruti, S., Chazot, P., Chiang, N., Chini, B., Chun, J., Cianciulli, A., Civelli, O., Clapp, L. H., Couture, R., Cox, H. M., Csaba, Z., Dahlgren, C., Dent, G., Douglas, S. D., Dournaud, P., Eguchi, S., Escher, E., Filardo, E. J., Fong, T., Fumagalli, M., Gainetdinov, R. R., Garelja, M. L., de Gasparo, M., Gerard, C., Gershengorn, M., Gobeil, F., Goodfriend, T. L., Goudet, C., Grätz, L., Gregory, K. J., Gundlach, A. L., Hamann, J., Hanson, J., Hauger, R. L., Hay, D. L., Heinemann, A., Herr, D., Hollenberg, M. D., Holliday, N. D., Horiuchi, M., Hoyer, D., Hunyady, L., Husain, A., IJzerman, A. P., Inagami, T., Jacobson, K. A., Jensen, R. T., Jockers, R., Jonnalagadda, D., Karnik, S., Kaupmann, K., Kemp, J., Kennedy, C., Kihara, Y., Kitazawa, T., Kozielewicz, P., Kreienkamp, H., Kukkonen, J. P., Langenhan, T., Larhammar, D., Leach, K., Lecca, D., Lee, J. D., Leeman, S. E., Leprince, J., Li, X. X., Lolait, S. J., Lupp, A., Macrae, R., Maguire, J., Malfacini, D., Mazella, J., McArdle, C. A., Melmed, S., Michel, M. C., Miller, L. J., Mitolo, V., Mouillac, B., Müller, C. E., Murphy, P. M., Nahon, J., Ngo, T., Norel, X., Nyimanu, D., O'Carroll, A., Offermanns, S., Panaro, M. A., Parmentier, M., Pertwee, R. G., Pin, J., Prossnitz, E. R., Quinn, M., Ramachandran, R., Ray, M., Reinscheid, R. K., Rondard, P., Rovati, G. E., Ruzza, C., Sanger, G. J., Schöneberg, T., Schulte, G., Schulz, S., Segaloff, D. L., Serhan, C. N., Singh, K. D., Smith, C. M., Stoddart, L. A., Sugimoto, Y., Summers, R., Tan, V. P., Thal, D., Thomas, W. W., Timmermans, P. B. M. W. M., Tirupula, K., Toll, L., Tulipano, G., Unal, H., Unger, T., Valant, C., Vanderheyden, P., Vaudry, D., Vaudry, H., Vilardaga, J., Walker, C. S., Wang, J. M., Ward, D. T., Wester, H., Willars, G. B., Williams, T. L., Woodruff, T. M., Yao, C. & Ye, R. D., Oct 2023, In: British Journal of Pharmacology. 180 Suppl 2, p. S23-S144

Research output: Contribution to journal › Journal article › Research › peer-review

Endocytic proteins mediating GPR15 receptor internalization provide insight into the underlying mechanisms

Deng, Y., Moo, Ee Von, Inoue, A. & Bräuner, Hans, 2023, In: FEBS Letters. 597, 11, p. 1528-1540

Research output: Contribution to journal › Journal article › Research › peer-review

Pharmacological characterization of novel small molecule agonists and antagonists for the orphan receptor GPR139

Pallareti, L., Rath, T. F., Trapkov, Boris, Tsonkov, T., Nielsen, A. T., Harpsøe, Kasper, Gentry, P. R., Bräuner, Hans, Gloriam, David E. & Foster, S. R., 2023, In: European Journal of Pharmacology. 943, 175553.

Research output: Contribution to journal › Journal article › Research › peer-review

Structure–activity relationship of GPR15L peptide analogues and investigation of their interaction with the GPR15 receptor

Deng, Y., Perez Almeria, C. V., van Gijzel, L., Schaller, Kay, Vedel, L., Gloriam, David E., Ulven, Trond & Bräuner, Hans, 2023, In: Basic and Clinical Pharmacology and Toxicology. 132, 6, p. 459-471

Research output: Contribution to journal › Journal article › Research › peer-review

Delineation of the GPR15 receptor-mediated Gα protein signalling profile in recombinant mammalian cells

Deng, Y., Moo, Ee Von, Almería, C. V. P., Gentry, P. R., Vedel, L., Mathiesen, Jesper M. & Bräuner, Hans, 2022, In: Basic and Clinical Pharmacology and Toxicology. 131, 2, p. 104-113

Research output: Contribution to journal › Journal article › Research › peer-review

Development of a medium throughput whole-cell microtiter plate Thr286 autophosphorylation assay for CaMKIIα using ELISA

Palmelund, L. B., van Woerden, G. M., Bräuner, Hans & Wellendorph, Petrine, 2022, In: Journal of Pharmacological and Toxicological Methods. 118, 8 p., 107226.

Research output: Contribution to journal › Journal article › Research › peer-review

Ligand-directed bias of G protein signaling at the dopamine D₂ receptor

Moo, Ee Von, Harpsøe, Kasper, Hauser, Alexander Sebastian, Masuho, I., Bräuner, Hans, Gloriam, David E. & Martemyanov, K. A., 2022, In: Cell Chemical Biology. 29, 2, p. 226-238

Research output: Contribution to journal › Journal article › Research › peer-review

Molecular insights into ligand recognition and G protein coupling of the neuromodulatory orphan receptor GPR139

Zhou, Y., Daver, H., Trapkov, B., Wu, L., Wu, M., Harpsøe, Kasper, Gentry, P. R., Liu, K., Larionova, M., Liu, J., Chen, N., Bräuner, Hans, Gloriam, David E., Hua, T. & Liu, Z. J., 2022, In: Cell Research. 32, 2, p. 210-213

Research output: Contribution to journal › Letter › Research › peer-review

Somatostatin venom analogs evolved by fish-hunting cone snails: From prey capture behavior to identifying drug leads

Ramiro, Iris Bea L. , Bjørn-Yoshimoto, Walden, Imperial, J. S., Gajewiak, J., Salcedo, P. F., Watkins, M., Taylor, D., Resager, W., Ueberheide, B., Bräuner, Hans, Whitby, F. G., Hill, C. P., Martin, L. F., Patwardhan, A., Concepcion, G. P., Olivera, B. M. & Safavi-Hemami, H., 2022, In: Science Advances. 8, 12, 16 p., eabk1410.

Research output: Contribution to journal › Journal article › Research › peer-review

Use of CRISPR/Cas9-edited HEK293 cells reveals that both conventional and novel protein kinase C isozymes are involved in mGlu_5a receptor internalization

van Senten, Jeffrey Roy, Møller, T. C., Moo, Ee Von, Seiersen, S. D. & Bräuner, Hans, 2022, In: Journal of Biological Chemistry. 298, 10, 16 p., 102466.

Research output: Contribution to journal › Journal article › Research › peer-review

Positive allosteric modulators of metabotropic glutamate receptor 5 as tool compounds to study signaling bias

Arsova, A., Møller, T. C., Hellyer, S. D., Vedel, L., Foster, S. R., Hansen, J. L., Bräuner, Hans & Gregory, K. J., 1 May 2021, In: Molecular Pharmacology. 99, 5, p. 328-241

Research output: Contribution to journal › Journal article › Research › peer-review

Arrestin-Dependent and -Independent Internalization of G Protein–Coupled Receptors: Methods, Mechanisms, and Implications on Cell Signaling

Moo, Ee Von, van Senten, Jeffrey Roy, Bräuner, Hans & Møller, T. C., 2021, In: Molecular Pharmacology. 99, 4, p. 242-255

Research output: Contribution to journal › Journal article › Research › peer-review

Asymmetric activation of the calcium-sensing receptor homodimer

Gao, Y., Robertson, M. J., Rahman, Sabrina Nalini, Seven, A. B., Zhang, C., Meyerowitz, J. G., Panova, O., Hannan, F. M., Thakker, R. V., Bräuner, Hans, Mathiesen, Jesper M. & Skiniotis, G., 2021, In: Nature. 595, p. 455-459

Research output: Contribution to journal › Journal article › Research › peer-review

GLP-1 Val8: A Biased GLP-1R Agonist with Altered Binding Kinetics and Impaired Release of Pancreatic Hormones in Rats

van der Velden, W. J. C., Smit, F. X., Christiansen, Charlotte Bayer, Møller, T. C., Hjortø, Gertrud Malene, Larsen, Olav, Schiellerup, S. P., Bräuner, Hans, Holst, Jens Juul, Hartmann, Bolette, Frimurer, Thomas Michael & Rosenkilde, Mette, 2021, In: ACS Pharmacology & Translational Science. 4, 1, p. 296-313 18 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Mutational Landscape of the Proglucagon-Derived Peptides

Lindquist, Peter, Madsen, Jakob Sture, Bräuner, Hans, Rosenkilde, Mette & Hauser, Alexander Sebastian, 2021, In: Frontiers in Endocrinology. 12, 14 p., 698511.

Research output: Contribution to journal › Journal article › Research › peer-review

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors

Alexander, S. P., Christopoulos, A., Davenport, A. P., Kelly, E., Mathie, A., Peters, J. A., Veale, E. L., Armstrong, J. F., Faccenda, E., Harding, S. D., Pawson, A. J., Southan, C., Davies, J. A., Abbracchio, M. P., Alexander, W., Al-Hosaini, K., Bäck, M., Barnes, N. M., Bathgate, R., Beaulieu, J-M. & 135 others, Bernstein, K. E., Bettler, B., Birdsall, N. J. M., Blaho, V., Boulay, F., Bousquet, C., Bräuner, Hans, Burnstock, G., Caló, G., Castaño, J. P., Catt, K. J., Ceruti, S., Chazot, P., Chiang, N., Chini, B., Chun, J., Cianciulli, A., Civelli, O., Clapp, L. H., Couture, R., Csaba, Z., Dahlgren, C., Dent, G., Singh, K. D., Douglas, S. D., Dournaud, P., Eguchi, S., Escher, E., Filardo, E. J., Fong, T., Fumagalli, M., Gainetdinov, R. R., Gasparo, M. D., Gerard, C., Gershengorn, M., Gobeil, F., Goodfriend, T. L., Goudet, C., Gregory, K. J., Gundlach, A. L., Hamann, J., Hanson, J., Hauger, R. L., Hay, D. L., Heinemann, A., Hollenberg, M. D., Holliday, N. D., Horiuchi, M., Hoyer, D., Hunyady, L., Husain, A., IJzerman, A. P., Inagami, T., Jacobson, K. A., Jensen, R. T., Jockers, R., Jonnalagadda, D., Karnik, S., Kaupmann, K., Kemp, J., Kennedy, C., Kihara, Y., Kitazawa, T., Kozielewicz, P., Kreienkamp, H., Kukkonen, J. P., Langenhan, T., Leach, K., Lecca, D., Lee, J. D., Leeman, S. E., Leprince, J., Li, X. X., Williams, T. L., Lolait, S. J., Lupp, A., Macrae, R., Maguire, J., Mazella, J., McArdle, C. A., Melmed, S., Michel, M. C., Miller, L. J., Mitolo, V., Mouillac, B., Müller, C. E., Murphy, P., Nahon, J., Ngo, T., Norel, X., Nyimanu, D., O'Carroll, A., Offermanns, S., Panaro, M. A., Parmentier, M., Pertwee, R. G., Pin, J., Prossnitz, E. R., Quinn, M., Ramachandran, R., Ray, M., Reinscheid, R. K., Rondard, P., Rovati, G. E., Ruzza, C., Sanger, G. J., Schöneberg, T., Schulte, G., Schulz, S., Segaloff, D. L., Serhan, C. N., Stoddart, L. A., Sugimoto, Y., Summers, R., Tan, V. P., Thal, D., Thomas, W. W., Timmermans, P. B. M. W. M., Tirupula, K., Tulipano, G., Unal, H., Unger, T., Valant, C., Vanderheyden, P., Vaudry, D., Vaudry, H., Vilardaga, J., Walker, C. S., Wang, J. M., Ward, D. T., Wester, H., Willars, G. B., Woodruff, T. M., Yao, C. & Ye, R. D., 2021, In: British Journal of Pharmacology. 178 , S1, p. S27-S156

Research output: Contribution to journal › Journal article › Research › peer-review

The Calcium-Sensing Receptor Is Essential for Calcium and Bicarbonate Sensitivity in Human Spermatozoa

Boisen, I. M., Rehfeld, Anders Aagaard, Mos, I., Poulsen, N. N., Nielsen, J. E., Schwarz, Peter, Rejnmark, L., Dissing, Steen, Bach-Mortensen, P., Juul, Anders, Bräuner, Hans, Lanske, B. & Blomberg Jensen, M., 2021, In: The Journal of clinical endocrinology and metabolism. 106, 4, p. e1775-e1792

Research output: Contribution to journal › Journal article › Research › peer-review

International Union of Basic and Clinical Pharmacology. CVIII. Calcium-Sensing Receptor Nomenclature, Pharmacology, and Function

Leach, K., Hannan, F. M., Josephs, T. M., Keller, A. N., Møller, T. C., Ward, D. T., Kallay, E., Mason, R. S., Thakker, R. V., Riccardi, D., Conigrave, A. D. & Bräuner, Hans, Jul 2020, In: Pharmacological Reviews. 72, 3, p. 558-604 47 p.

Research output: Contribution to journal › Review › Research › peer-review

Heterozygous Mutation (Q459R) in the Calcium-Sensing Receptor Gene Causes Familial Hypocalciuric Hypercalcemia 1 (FHH1)

Boisen, I. M., Mos, I., Lerche-Black, E. M., Juul, Anders, Bräuner, Hans & Blomberg Jensen, M., 1 Apr 2020, In: The Journal of clinical endocrinology and metabolism. 105, 4, p. e1322-e1330

Research output: Contribution to journal › Journal article › Research › peer-review

Novel approaches leading towards peptide GPCR de-orphanisation

Hauser, Alexander Sebastian, Gloriam, David E., Bräuner, Hans & Foster, S. R., 1 Mar 2020, In: British Journal of Pharmacology. 177, 5, p. 961-968 8 p.

Research output: Contribution to journal › Review › Research › peer-review

Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics

Pedersen, M. F., Wrobel, T. M., Marcher, Emil, Pedersen, D. S., Møller, T. C., Gabriele, F., Pedersen, H., Matosiuk, D., Foster, S. R., Bouvier, M. & Bräuner, Hans, 2020, In: Neuropharmacology. 166, 13 p., 107718.

Research output: Contribution to journal › Journal article › Research › peer-review

Delineation of molecular determinants for FR900359 inhibition of G_q/11 unlocks inhibition of Gα_s

Boesgaard, M. W., Harpsøe, Kasper, Malmberg, M., Underwood, C. R., Inoue, A., Mathiesen, Jesper M., König, G. M., Kostenis, E., Gloriam, David E. & Bräuner, Hans, 2020, In: Journal of Biological Chemistry. 295, 40, p. 13850-13861

Research output: Contribution to journal › Journal article › Research › peer-review

Detailed in vitro pharmacological characterization of clinically tested negative allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5)

Arsova, A., Møller, T. C., Vedel, L., Hansen, J. L., Foster, S. R., Gregory, K. J. & Bräuner, Hans, 2020, In: Molecular Pharmacology. 98, 1, p. 49-60

Research output: Contribution to journal › Journal article › Research › peer-review

Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells

Møller, T. C., Pedersen, M. F., van Senten, Jeffrey Roy, Seiersen, S. D., Mathiesen, Jesper M., Bouvier, M. & Bräuner, Hans, 2020, In: Scientific Reports. 10, 1, 13 p., 17395.

Research output: Contribution to journal › Journal article › Research › peer-review

Enhanced agonist residence time, internalization rate and signalling of the GIP receptor variant [E354Q] facilitate receptor desensitization and long-term impairment of the GIP system

Gabe, M. B. N., van der Velden, W. J. C., Gadgaard, S., Smit, F. X., Hartmann, Bolette, Bräuner, Hans & Rosenkilde, Mette, 2020, In: Basic & Clinical Pharmacology & Toxicology. 126, p. 122-132

Research output: Contribution to journal › Journal article › Research › peer-review

G protein-coupled receptor pharmacology-The next generation

Bräuner, Hans, Rosenkilde, Mette, Gether, Ulrik & Gloriam, David E., 2020, In: Basic & Clinical Pharmacology & Toxicology. 126, Supplement 6, p. 3-4 2 p.

Research output: Contribution to journal › Editorial › Research

Pharmacology and physiological function of the orphan GPRC6A receptor

Jorgensen, C. V. & Bräuner, Hans, 2020, In: Basic & Clinical Pharmacology & Toxicology. 126, p. 77-87 11 p.

Research output: Contribution to journal › Review › Research › peer-review

The selective 5-HT2A receptor agonist 25CN-NBOH: structure-activity relationship, in vivo pharmacology, and in vitro and ex vivo binding characteristics of [3H]25CN-NBOH

Jensen, Anders A., Halberstadt, A. L., Marcher, Emil, Odland, Anna Ulstein, Chatha, M., Speth, N., Liebscher, G., Hansen, M., Bräuner, Hans, Palner, M., Andreasen T., Jesper & Kristensen, Jesper Langgaard, 2020, In: Biochemical Pharmacology. 177, 16 p., 113979.

Research output: Contribution to journal › Journal article › Research › peer-review

Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors

Foster, S. R., Hauser, Alexander Sebastian, Vedel, L., Strachan, R. T., Huang, X., Gavin, A. C., Shah, S. D., Nayak, A. P., Haugaard-Kedström, L. M., Penn, R. B., Roth, B. L., Bräuner, Hans & Gloriam, David E., 31 Oct 2019, In: Cell. 179, 4, p. 895-908

Research output: Contribution to journal › Journal article › Research › peer-review

Calcium-Sensing Receptor Internalization Is β-Arrestin-Dependent and Modulated by Allosteric Ligands

Mos, I., Jacobsen, S. E., Foster, S. R. & Bräuner, Hans, Oct 2019, In: Molecular Pharmacology. 96, 4, p. 463-474 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Probing the Existence of a Metastable Binding Site at the β2-Adrenergic Receptor with Homobivalent Bitopic Ligands

Gaiser, B. I., Danielsen, M., Marcher, Emil, Røpke Jørgensen, K., Wróbel, T. M., Frykman, M., Johansson, H., Bräuner, Hans, Gloriam, David E., Mathiesen, Jesper M. & Sejer Pedersen, D., 12 Sep 2019, In: Journal of Medicinal Chemistry. 62, 17, p. 7806-7839 34 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Pharmacology and function of the orphan GPR139 G protein-coupled receptor

Vedel, L., Nøhr, A. C., Gloriam, David E. & Bräuner, Hans, 27 May 2019, In: Basic & Clinical Pharmacology & Toxicology. 126, p. 35-46

Research output: Contribution to journal › Review › Research › peer-review

Metabolic and skeletal homeostasis are maintained in full locus GPRC6A knockout mice

Jørgensen, C. V., Gasparini, S. J., Tu, J., Zhou, H., Seibel, M. J. & Bräuner, Hans, 12 Apr 2019, In: Scientific Reports. 9, 1, 8 p., 5995.

Research output: Contribution to journal › Journal article › Research › peer-review

Rational design of a heterotrimeric G protein α subunit with artificial inhibitor sensitivity

Malfacini, D., Patt, J., Annala, S., Harpsøe, Kasper, Eryilmaz, F., Reher, R., Crüsemann, M., Hanke, W., Zhang, H., Tietze, D., Gloriam, David E., Bräuner, Hans, Strømgaard, Kristian, König, G. M., Inoue, A., Gomeza, J. & Kostenis, E., 12 Apr 2019, In: The Journal of Biological Chemistry. 294, 15, p. 5747-5758

Research output: Contribution to journal › Journal article › Research › peer-review

Label-free dynamic mass redistribution analysis of endogenous adrenergic receptor signaling in primary preadipocytes and differentiated adipocytes

Jørgensen, C. V., Zhou, H., Seibel, M. J. & Bräuner, Hans, 1 Apr 2019, In: Journal of Pharmacological and Toxicological Methods. 97, p. 59-66 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Structure–Activity Relationship Studies of the Natural Product G _q/11 Protein Inhibitor YM-254890

Xiong, X. F., Zhang, H., Boesgaard, M. W., Underwood, C. R., Bräuner, Hans & Strømgaard, Kristian, Apr 2019, In: ChemMedChem. 14, 8, p. 865-870

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of a novel scaffold for a small molecule GPR139 receptor agonist

Nøhr, A. C., Shehata, M. A., Palmer, D., Pokhrel, R., Vallianou, M., Foster, S. R., Gentry, P. R., Gloriam, David E. & Bräuner, Hans, 7 Mar 2019, In: Scientific Reports. 9, 1, 10 p., 3802.

Research output: Contribution to journal › Journal article › Research › peer-review

Human GIP(3-30)NH inhibits G protein-dependent as well as G protein-independent signaling and is selective for the GIP receptor with high-affinity binding to primate but not rodent GIP receptors

Gabe, M. B. N., Sparre-Ulrich, A. H., Pedersen, M. F., Gasbjerg, Lærke Smidt, Inoue, A., Bräuner, Hans, Hartmann, Bolette & Rosenkilde, M. M., 31 Jan 2018, In: Biochemical Pharmacology. 150, p. 97-107 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Structure–activity relationship and conformational studies of the natural product cyclic depsipeptides YM-254890 and FR900359

Zhang, H., Nielsen, A. L., Boesgaard, M. W., Harpsøe, Kasper, Daly, N. L., Xiong, X., Underwood, C. R., Haugaard-kedström, L. M., Bräuner, Hans, Gloriam, David E. & Strømgaard, Kristian, 2018, In: European Journal of Medicinal Chemistry. 156, p. 847-860

Research output: Contribution to journal › Journal article › Research › peer-review

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview

CGTP Collaborators, C. C., Dec 2017, In: British Journal of Pharmacology. 174, p. S1-S16

Research output: Contribution to journal › Journal article › Research › peer-review

Structure-Activity Relationship, Pharmacological Characterization, and Molecular Modeling of Noncompetitive Inhibitors of the Betaine/γ-Aminobutyric Acid Transporter 1 (BGT1)

Jørgensen, L., Al-Khawaja, A., Kickinger, S., Vogensen, S. B., Skovgaard-Petersen, J., Rosenthal, E., Borkar, N., Löffler, R., Madsen, K. K., Bräuner, Hans, Schousboe, Arne, Ecker, G. F., Wellendorph, Petrine & Clausen, Rasmus Prætorius, 9 Oct 2017, In: Journal of Medicinal Chemistry. 60, 21, p. 8834-8846

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of AICP as a GluN2C-Selective N-Methyl-d-Aspartate Receptor Superagonist at the GluN1 Glycine Site

Jessen, M., Frederiksen, K., Yi, F., Clausen, Rasmus Prætorius, Hansen, K. B., Bräuner, Hans, Kilburn, J. P. & Damholt, A., Aug 2017, In: Molecular Pharmacology. 92, 2, p. 151-161 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Applying label-free dynamic mass redistribution assay for studying endogenous FPR1 receptor signalling in human neutrophils

Christensen, H. B., Gloriam, David E., Pedersen, D. S., Cowland, J. B., Borregaard, N. & Bräuner, Hans, 15 Jul 2017, In: Journal of Pharmacological and Toxicological Methods. 88, Pt 1, p. 72-78 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of Histamine H3 Receptor Ligands Using a New Crystal Structure Fragment-based Method

Frandsen, I. O., Boesgaard, M. W., Fidom, K., Hauser, Alexander Sebastian, Isberg, V., Bräuner, Hans, Wellendorph, Petrine & Gloriam, David E., 6 Jul 2017, In: Scientific Reports. 7, 1, 10 p., 4829.

Research output: Contribution to journal › Journal article › Research › peer-review

Structure-Activity Relationship Studies of the Cyclic Depsipeptide Natural Product YM-254890, Targeting the Gq Protein

Zhang, H., Xiong, X., Boesgaard, M. W., Underwood, C. R., Bräuner, Hans & Strømgaard, Kristian, 7 Jun 2017, In: ChemMedChem. 12, 11, p. 830-834 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The GPR139 reference agonists 1a and 7c, and tryptophan and phenylalanine share a common binding site

Shehata, M. A., Jensen, A. C. N., Jespers, W., Floryan, L., Isberg, V., Andersen, K. B., Åqvist, J., Gutiérrez-de-Terán, H., Bräuner, Hans & Gloriam, David E., 25 Apr 2017, In: Scientific Reports. 7, 9 p., 1128.

Research output: Contribution to journal › Journal article › Research › peer-review