Rasmus Prætorius Clausen

• Presentation
• Research outputs

• neuromedicinal chemistry
• epigenetic medicinal chemistry
• biostructure based SAR studies
• peptide and protein based ligands
• organic synthesis

Selected publications

1. Published

   Subtype-Specific Agonists for NMDA Receptor Glycine Binding Sites

   Maolanon, A. R., Risgaard, R., Wang, S. Y., Snoep, Y., Papangelis, Athanasios, Yi, F., Holley, D., Barslund, A. F., Svenstrup, N., Hansen, K. B. & Clausen, Rasmus Prætorius, 16 Aug 2017, In : ACS Chemical Neuroscience. 8, 8, p. 1681-1687 7 p.

   Research output: Contribution to journal › Letter › Research › peer-review

2. Published

   Tweaking subtype-selectivity and agonist efficacy at (S)-2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propionic acid (AMPA) receptors in a small series of BnTetAMPA analogues

   Wang, S., Larsen, Y., Navarrete, C. V., Jensen, Anders A., Nielsen, Birgitte, Al-Musaed, A., Frydenvang, Karla Andrea, Kastrup, Jette Sandholm Jensen, Pickering, Darryl S & Clausen, Rasmus Prætorius, 2016, In : Journal of Medicinal Chemistry. 59, 5, p. 2244-2254 11 p.

   Research output: Contribution to journal › Journal article › Research › peer-review

3. Published

   Substrate- and Cofactor-independent Inhibition of Histone Demethylase KDM4C

   Leurs, U., Lohse, Brian, Rand, Kasper Dyrberg, Ming, S., Riise, E. S., Cole, P. A., Kristensen, Jesper Langgaard & Clausen, Rasmus Prætorius, 11 Jul 2014, In : A C S Chemical Biology. 9, 9, p. 2131-2138 8 p.

   Research output: Contribution to journal › Journal article › Research › peer-review

4. Published

   Targeting histone lysine demethylases by truncating the histone 3 tail to obtain selective substrate-based inhibitors

   Lohse, Brian, Nielsen, A. L., Kristensen, J. B. L., Helgstrand, C., Cloos, Paul, Olsen, L., Gajhede, Michael, Clausen, Rasmus Prætorius & Kristensen, Jesper Langgaard, 19 Sep 2011, In : Angewandte Chemie International Edition. 50, 39, p. 9100-9103

   Research output: Contribution to journal › Journal article › Research › peer-review

5. Published

   α4βδ GABA receptors are high-affinity targets for γ-hydroxybutyric acid (GHB)

   Absalom, N., Karim, N., Eghorn, L. F., Villumsen, I. S., Bay, T., Bräuner-Osborne, Hans, Frølund, Bente, Clausen, Rasmus Prætorius, Olsen, Jesper Velgaard, Knudsen, Gitte Moos, Chebib, M. & Wellendorph, Petrine, 14 Aug 2012, In : Proceedings of the National Academy of Sciences USA (PNAS). 109, 33, p. 13404-13409 6 p.

   Research output: Contribution to journal › Journal article › Research › peer-review