Chuna Ram Choudhary
professor, group leader
Choudhary Group
Blegdamsvej 3, 2200 København N., Bygning 6, Building: 06-6-14
- 2020
- Published
Sequencing of the First Draft of the Human Acetylome
Choudhary, Chuna Ram & Mann, Matthias, 2020, In : Clinical Chemistry. 66, 6, p. 852-853 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation
Khoa, L. T. P., Tsan, Y., Mao, F., Kremer, D. M., Sajjakulnukit, P., Zhang, L., Zhou, B., Tong, X., Bhanu, N. V., Choudhary, Chuna Ram, Garcia, B. A., Yin, L., Smith, G. D., Saunders, T. L., Bielas, S. L., Lyssiotis, C. A. & Dou, Y., 2020, In : Cell Stem Cell. 27, 3, p. 441-458.e10 29 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HBO1 is required for the maintenance of leukaemia stem cells
MacPherson, L., Anokye, J., Yeung, M. M., Lam, E. Y. N., Chan, Y., Weng, C., Yeh, P., Knezevic, K., Butler, M. S., Hoegl, A., Chan, K., Burr, M. L., Gearing, L. J., Willson, T., Liu, J., Choi, J., Yang, Y., Bilardi, R. A., Falk, H., Nghi Nguyen, Stupple, P. A., Peat, T. S., Zhang, M., De Silva, M., Carrasco-Pozo, C., Avery, V. M., Khoo, S., Dolezal, O., Dennis, M. L., Nuttall, S., Surjadi, R., Newman, J., Ren, B., Leaver, D. J., Sun, Y., Baell, J. B., Dovey, O., Vassiliou, G. S., Grebien, F., Dawson, S., Street, I. P., Monahan, B. J., Burns, C. J., Choudhary, Chuna Ram, Blewitt, M. E., Voss, A. K., Thomas, T. & Dawson, M. A., 2020, In : Nature. 577, 7789, p. 266-270Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Equilibrium between nascent and parental MCM proteins protects replicating genomes
Sedlackova, Hana, Rask, M., Gupta, R., Choudhary, Chuna Ram, Somyajit, K. & Lukas, Jiri, Oct 2020, In : Nature. 34 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Proteomic exploration of lysine acetylation signaling
Choudhary, Chuna Ram, 2019, In : Molecular & Cellular Proteomics. 18, 8, p. S25 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Analysis of human acetylation stoichiometry defines mechanistic constraints on protein regulation
Hansen, B. K., Gupta, R., Baldus, L., Lyon, D., Narita, Takeo, Lammers, M., Choudhary, Chuna Ram & Weinert, B. T., 2019, In : Nature Communications. 10, 11 p., 1055.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functions and mechanisms of non-histone protein acetylation
Narita, Takeo, Weinert, B. T. & Choudhary, Chuna Ram, 2019, In : Nature Reviews. Molecular Cell Biology. 20, p. 156-174 19 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Analysis and Interpretation of Protein Post-Translational Modification Site Stoichiometry
Prus, Gabriela Zofia, Hoegl, A., Weinert, B. T. & Choudhary, Chuna Ram, 2019, In : Trends in Biochemical Sciences. 44, 11, p. 943-960Research output: Contribution to journal › Review › Research › peer-review
- Published
Acetylation of intrinsically disordered regions regulates phase separation
Saito, M., Hess, D., Eglinger, J., Fritsch, A. W., Kreysing, M., Weinert, B. T., Choudhary, Chuna Ram & Matthias, P., Jan 2019, In : Nature Chemical Biology. 15, 1, p. 51-61Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage
Borisova, M. E., Voigt, A., Tollenaere, M. A. X., Sahu, S. K., Juretschke, T., Kreim, N., Mailand, Niels, Choudhary, Chuna Ram, Bekker-Jensen, Simon Holst, Akutsu, M., Wagner, S. A. & Beli, P., 2018, In : Nature Communications. 9, p. 1-16 16 p., 1017.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
STK3 is a therapeutic target for a subset of acute myeloid leukemias
Camgoz, A., Paszkowski-Rogacz, M., Satpathy, S., Wermke, M., Hamann, M. V., von Bonin, M., Choudhary, Chuna Ram, Knapp, S. & Buchholz, F., 2018, In : OncoTarget. 9, 39, p. 25458-25473 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity
Gupta, R., Somyajit, K., Narita, Takeo, Maskey, E., Stanlie, A., Kremer, M., Typas, Dimitris, Lammers, M., Mailand, Niels, Nussenzweig, A., Lukas, Jiri & Choudhary, Chuna Ram, 2018, In : Cell. 173, 4, p. 972-988Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome
Weinert, B. T., Narita, Takeo, Satpathy, S., Srinivasan, Balaji, Hansen, B. K., Schölz, C., Hamilton, William, Zucconi, B. E., Wang, W. W., Liu, W. R., Brickman, Joshua Mark, Kesicki, E. A., Lai, A., Bromberg, K. D., Cole, P. A. & Choudhary, Chuna Ram, 2018, In : Cell. 174, 1, p. 231-244.e12 27 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deletion of APC7 or APC16 Allows Proliferation of Human Cells without the Spindle Assembly Checkpoint
Wild, T., Budzowska, M., Hellmuth, S., Eibes, S., Karemore, Gopal, Barisic, Marin, Stemmann, O. & Choudhary, Chuna Ram, 2018, In : Cell Reports. 25, 9, 18 p., 2317-2328.e5.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
lncRNA Panct1 Maintains Mouse Embryonic Stem Cell Identity by Regulating TOBF1 Recruitment to Oct-Sox Sequences in Early G1
Chakraborty, D., Paszkowski-Rogacz, M., Berger, N., Ding, L., Mircetic, J., Fu, J., Iesmantavicius, V., Choudhary, Chuna Ram, Anastassiadis, K., Stewart, A. F. & Buchholz, F., 12 Dec 2017, In : Cell Reports. 21, 11, p. 3012-3021 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours
Lasko, L. M., Jakob, C. G., Edalji, R. P., Qiu, W., Montgomery, D., Digiammarino, E. L., Hansen, T. M., Risi, R. M., Frey, R., Manaves, V., Shaw, B., Algire, M., Hessler, P., Lam, L. T., Uziel, T., Faivre, E., Ferguson, D., Buchanan, F. G., Martin, R. L., Torrent, M., Chiang, G. G., Karukurichi, K., Langston, J. W., Weinert, B. T., Choudhary, Chuna Ram, de Vries, P., Van Drie, J. H., McElligott, D., Kesicki, E., Marmorstein, R., Sun, C., Cole, P. A., Rosenberg, S. H., Michaelides, M. R., Lai, A. & Bromberg, K. D., 5 Oct 2017, In : Nature. 550, 7674, p. 128-132 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Redox-sensitive alteration of replisome architecture safeguards genome integrity
Somyajit, K., Gupta, R., Sedlackova, Hana, Neelsen, K. J., Ochs, F., Rask, M., Choudhary, Chuna Ram & Lukas, Jiri, 10 Nov 2017, In : Science. 358, 6364, p. 797-802 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Accurate quantification of site-specific acetylation stoichiometry reveals the impact of sirtuin deacetylase CobB on the E. coli acetylome
Weinert, B. T., Satpathy, S., Hansen, B. K., Lyon, D., Jensen, Lars Juhl & Choudhary, Chuna Ram, May 2017, In : Molecular and Cellular Proteomics. 16, p. 759-769Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Deubiquitylating enzyme USP9x regulates hippo pathway activity by controlling angiomotin protein turnover
Nguyen, T. H., Andrejeva, D., Gupta, R., Choudhary, Chuna Ram, Hong, X., Eichhorn, P. J., Loya, Anand Chainsukh & Cohen, S. M., 29 Mar 2016, In : Cell Discovery. 2, 13 p., 16001.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance
Pinela da Silva, S. C., Altmannova, V., Luke-Glaser, S., Henriksen, P., Gallina, Irene, Yang, X., Choudhary, Chuna Ram, Luke, B., Krejci, L. & Lisby, Michael, 2016, In : Genes & Development. 30, 6, p. 700-717 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex
Starnes, L. M., Su, D., Pikkupeura, Laura Maarit, Weinert, B. T., Santos, M. A., Mund, Andreas, Soria, R., Cho, Y., Pozdnyakova, I., Kubec Højfeldt, M., Lages Lino Vala, A., Yang, W., López-Méndez, B., Lee, J., Peng, W., Yuan, J., Ge, K., Montoya, Guillermo, Nussenzweig, A., Choudhary, Chuna Ram & Daniel, J. A., 15 Jan 2016, In : Genes & Development. 30, 2, p. 149-163 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SPATA2 links CYLD to the TNF-α receptor signaling complex and modulates the receptor signaling outcomes
Wagner, S. A., Satpathy, S., Beli, P. & Choudhary, Chuna Ram, 1 Sep 2016, In : E M B O Journal. 35, 17, p. 1868-1884Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Spindle Assembly Checkpoint Is Not Essential for Viability of Human Cells with Genetically Lowered APC/C Activity
Wild, T., Larsen, M. S. Y., Narita, Takeo, Schou, J., Nilsson, Jakob & Choudhary, Chuna Ram, 1 Mar 2016, In : Cell Reports. 14, 8, p. 1829-40 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits
Acosta-Alvear, D., Cho, M. Y., Wild, T., Buchholz, T. J., Lerner, A. G., Simakova, O., Hahn, J., Korde, N., Landgren, O., Maric, I., Choudhary, Chuna Ram, Walter, P., Weissman, J. S. & Kampmann, M., 1 Sep 2015, In : eLife. 4, p. 1-19 e08153.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells
Bursomanno, S., Beli, P., Khan, A. M., Minocherhomji, S., Wagner, S. A., Bekker-Jensen, Simon Holst, Mailand, Niels, Choudhary, Chuna Ram, Hickson, Ian David & Liu, Ying, Jan 2015, In : DNA Repair. 25, p. 84-96 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells
Ding, L., Paszkowski-Rogacz, M., Winzi, M., Chakraborty, D., Theis, M., Singh, S., Ciotta, G., Poser, I., Roguev, A., Chu, W. K., Choudhary, Chuna Ram, Mann, Matthias, Stewart, A. F., Krogan, N. & Buchholz, F., 26 Aug 2015, In : Cell Systems. 1, 2, p. 141-151 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ubiquitin-SUMO Circuitry Controls Activated Fanconi Anemia ID Complex Dosage in Response to DNA Damage
Gibbs-Seymour, I., Oka, Y., Rajendra, E., Weinert, B. T., Passmore, L. A., Patel, K. J., Olsen, Jesper Velgaard, Choudhary, Chuna Ram, Bekker-Jensen, Simon Holst & Mailand, Niels, Jan 2015, In : Molecular Cell. 57, 1, p. 150-64 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systems-wide analysis of BCR signalosomes and downstream phosphorylation and ubiquitylation
Satpathy, S., Wagner, S. A., Beli, P., Gupta, R., Kristiansen, T. A., Malinova, D., Francavilla, C., Tolar, P., Bishop, G. A., Hostager, B. S. & Choudhary, Chuna Ram, 2015, In : Molecular Systems Biology. 11, 6, 810.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acetylation site specificities of lysine deacetylase inhibitors in human cells
Schölz, C., Weinert, B. T., Wagner, S. A., Beli, P., Miyake, Y., Qi, J., Jensen, Lars Juhl, Streicher, W., McCarthy, A. R., Westwood, N. J., Lain, S., Cox, J., Matthias, P., Mann, M., Bradner, J. E. & Choudhary, Chuna Ram, 2015, In : Nature Biotechnology. 33, p. 415–423Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Avoiding abundance bias in the functional annotation of posttranslationally modified proteins
Schölz, C., Lyon, D., Refsgaard, J. C., Jensen, Lars Juhl, Choudhary, Chuna Ram & Weinert, B. T., Nov 2015, In : Nature Methods. 12, p. 1003-4 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage
Thorslund, T., Ripplinger, A., Hoffmann, Saskia, Wild, T., Uckelmann, M., Villumsen, B., Narita, Takeo, Sixma, T. K., Choudhary, Chuna Ram, Bekker-Jensen, Simon Holst & Mailand, Niels, 19 Nov 2015, In : Nature. 527, 7578, p. 389-93 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Analysis of acetylation stoichiometry suggests that SIRT3 repairs nonenzymatic acetylation lesions
Weinert, B. T., Moustafa, T., Iesmantavicius, V., Zechner, R. & Choudhary, Chuna Ram, 3 Nov 2015, In : E M B O Journal. 34, 21, p. 2620-2632 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
A quantitative 14-3-3 interaction screen connects the nuclear exosome targeting complex to the DNA damage response
Blasius, M., Wagner, S. A., Choudhary, Chuna Ram, Bartek, J. & Jackson, S. P., 4 Sep 2014, In : Genes & Development. 28, 18, p. 1977-1982 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The growing landscape of lysine acetylation links metabolism and cell signalling
Choudhary, Chuna Ram, Weinert, B. T., Nishida, Y., Verdin, E. & Mann, Matthias, 23 Jul 2014, In : Nature Reviews. Molecular Cell Biology. 15, 8, p. 536-50 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Convergence of Ubiquitylation and Phosphorylation Signaling in Rapamycin-Treated Yeast Cells
Iesmantavicius, V., Weinert, B. T. & Choudhary, Chuna Ram, 24 Jun 2014, In : Molecular & Cellular Proteomics. 13, 8, p. 1979-92 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Time-resolved dissection of early phosphoproteome and ensuing proteome changes in response to TGF-β
J D'Souza, R. C., Knittle, A. M., Nagaraj, N., van Dinther, M., Choudhary, Chuna Ram, Ten Dijke, P., Mann, Matthias & Sharma, K., Jul 2014, In : Science signaling. 7, 335, p. rs5 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Specificity and commonality of the phosphoinositide-binding proteome analyzed by quantitative mass spectrometry
Jungmichel, S., Sylvestersen, K. B., Choudhary, Chuna Ram, Nguyen, S., Mann, Matthias & Nielsen, Michael Lund, 13 Feb 2014, In : Cell Reports. 6, 3, p. 578-91 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells
Oka, Y., Varmark, H., Vitting-Seerup, Kristoffer, Beli, P., Waage, J. E., Hakobyan, A., Mistrik, M., Choudhary, Chuna Ram, Rohde, M., Bekker-Jensen, Simon Holst & Mailand, Niels, 2014, In : E M B O Reports. 15, 9, p. 956-964 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acetylation dynamics and stoichiometry in Saccharomyces cerevisiae
Weinert, B. T., Iesmantavicius, V., Moustafa, T., Schölz, C., Wagner, S. A., Magnes, C., Zechner, R. & Choudhary, Chuna Ram, 31 Jan 2014, In : Molecular Systems Biology. 10, 1, p. 716 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
OTULIN Restricts Met1-Linked Ubiquitination to Control Innate Immune Signaling
Fiil, Berthe Katrine, Damgaard, R. B., Wagner, S. A., Keusekotten, K., Fritsch, M., Bekker-Jensen, Simon Holst, Mailand, Niels, Choudhary, Chuna Ram, Komander, D. & Gyrd-Hansen, Mads, 27 Jun 2013, In : Molecular Cell. 50, 6, p. 818-30 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response
Poulsen, S. L., Hansen, R. K., Wagner, S. A., van Cuijk, L., van Belle, G. J., Streicher, W., Wikström, M., Choudhary, Chuna Ram, Houtsmuller, A. B., Marteijn, J. A., Bekker-Jensen, Simon Holst & Mailand, Niels, 10 Jun 2013, In : Journal of Cell Biology. 201, 6, p. 797-807 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis
Villumsen, B. H., Danielsen, J. R., Povlsen, L., Sylvestersen, K. B., Merdes, A., Beli, P., Yang, Y., Choudhary, Chuna Ram, Nielsen, Michael Lund, Mailand, Niels & Bekker-Jensen, Simon Holst, 11 Oct 2013, In : E M B O Journal. 32, 23, p. 3029-3040Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli
Weinert, B. T., Iesmantavicius, V., Wagner, S. A., Schölz, C., Gummesson, Bertil, Beli, P., Nyström, T. & Choudhary, Chuna Ram, 25 Jul 2013, In : Molecular Cell. 51, 2, p. 265-272 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lysine succinylation is a frequently occurring modification in prokaryotes and eukaryotes and extensively overlaps with acetylation
Weinert, B. T., Schölz, C., Wagner, S. A., Iesmantavicius, V., Su, D., Daniel, J. A. & Choudhary, Chuna Ram, 29 Aug 2013, In : Cell Reports. 4, 4, p. 842-51 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response
Beli, P., Lukashchuk, N., Wagner, S. A., Weinert, B. T., Olsen, Jesper Velgaard, Baskcomb, L., Mann, Matthias, Jackson, S. P. & Choudhary, Chuna Ram, 2012, In : Molecular Cell. 46, 2, p. 212-25 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae
Henriksen, P., Wagner, S. A., Weinert, B. T., Sharma, S., Bacinskaja, G., Rehman, M., Juffer, A. H., Walther, T. C., Lisby, Michael & Choudhary, Chuna Ram, 2012, In : Molecular & Cellular Proteomics. 11, 11, p. 1510-1522 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns
Lundby, Alicia, Hansen, K. L., Weinert, B. T., Breinholt Bekker-Jensen, D., Secher, A., Skovgaard, T., Kelstrup, C., Dmytriyev, A., Choudhary, Chuna Ram, Lundby, C. & Olsen, Jesper Velgaard, 30 Aug 2012, In : Cell Reports. 2, 2, p. 419-431 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks
Mosbech, A., Gibbs-Seymour, I., Kagias, K., Thorslund, T., Beli, P., Povlsen, L., Nielsen, Sofie Vincents, Smedegaard, S., Sedgwick, G., Lukas, Claudia, Hartmann-Petersen, Rasmus, Lukas, Jiri, Choudhary, Chuna Ram, Pocock, R. D. J., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In : Nature Structural and Molecular Biology. 19, 11, p. 1084-92 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass
Povlsen, L. K., Beli, P., Wagner, S. A., Poulsen, S. L., Sylvestersen, K. B., Poulsen, J. W., Nielsen, Michael Lund, Bekker-Jensen, Simon Holst, Mailand, Niels & Choudhary, Chuna Ram, Oct 2012, In : Nature Cell Biology. 14, 10, p. 1089-98 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SOCS1 cooperates with FLT3-ITD in the development of myeloproliferative disease by promoting the escape from external cytokine control
Reddy, P. N. G., Serve, H., Brandts, C. H., Sargin, B., Choudhary, Chuna Ram, Müller-Tidow, C., Berdel, W. E., Stein, S. & Grez, M., 23 Aug 2012, In : Blood. 120, 8, p. 1691-1702 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3
Sol, E. M., Wagner, S. A., Weinert, B. T., Kumar, A., Kim, H., Deng, C. & Choudhary, Chuna Ram, 7 Dec 2012, In : PloS one. 7, 12, p. e50545Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomic analyses reveal divergent ubiquitylation site patterns in murinetissues
Wagner, S. A., Beli, P., Weinert, B. T., Schölz, C. F., Kelstrup, C. D., Young, C., Nielsen, Michael Lund, Olsen, Jesper Velgaard, Brakebusch, Cord Herbert & Choudhary, Chuna Ram, 2012, In : Molecular & Cellular Proteomics.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
A phospho-proteomic screen identifies substrates of the checkpoint kinase Chk1
Blasius, M., Forment, J. V., Thakkar, N., Wagner, S. A., Choudhary, Chuna Ram & Jackson, S. P., 2011, In : Genome Biology (Online Edition). 12, 8, p. R78Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles
Wagner, S. A., Beli, P., Weinert, B. T., Nielsen, Michael Lund, Cox, J., Mann, Matthias & Choudhary, Chuna Ram, 1 Oct 2011, In : Molecular and Cellular Proteomics. 10, 10, p. M111.013284Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation
Weinert, B. T., Wagner, S. A., Horn, H., Henriksen, P., Liu, W. R., Olsen, Jesper Velgaard, Jensen, Lars Juhl & Choudhary, Chuna Ram, 2011, In : Science Signaling. 4, 183, p. ra48Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth
Wild, P., Farhan, H., McEwan, D. G., Wagner, S., Rogov, V. V., Brady, N. R., Richter, B., Korac, J., Waidmann, O., Choudhary, Chuna Ram, Dötsch, V., Bumann, D. & Dikic, I., 8 Jul 2011, In : Science. 333, 6039, p. 228-33 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Decoding signalling networks by mass spectrometry-based proteomics
Choudhary, Chuna Ram & Mann, Matthias, 1 Jun 2010, In : Nature Reviews. Molecular Cell Biology. 11, 6, p. 427-39 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predicting post-translational lysine acetylation using support vector machines
Gnad, F., Ren, S., Choudhary, Chuna Ram, Cox, J. & Mann, M., 1 Jul 2010, In : Bioinformatics. 26, 13, p. 1666-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Lysine acetylation targets protein complexes and co-regulates major cellular functions
Choudhary, Chuna Ram, Kumar, C., Gnad, F., Nielsen, Michael Lund, Rehman, M., Walther, T. C., Olsen, Jesper Velgaard & Mann, Matthias, 2009, In : Science. 325, 5942, p. 834-40 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes
Choudhary, Chuna Ram, Olsen, Jesper Velgaard, Brandts, C., Cox, J., Reddy, P. N. G., Böhmer, F. D., Gerke, V., Schmidt-Arras, D., Berdel, W. E., Müller-Tidow, C., Mann, Matthias & Serve, H., 2009, In : Molecular Cell. 36, 2, p. 326-39 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
Identification of a novel activating mutation (Y842C) within the activation loop of FLT3 in patients with acute myeloid leukemia (AML)
Kindler, T., Breitenbuecher, F., Kasper, S., Estey, E., Giles, F., Feldman, E., Ehninger, G., Schiller, G., Klimek, V., Nimer, S. D., Gratwohl, A., Choudhary, Chuna Ram, Mueller-Tidow, C., Serve, H., Gschaidmeier, H., Cohen, P. S., Huber, C. & Fischer, T., 2005, In : Blood. 105, 1, p. 335-40 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 13781159
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486
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Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage
Research output: Contribution to journal › Letter › Research › peer-review
Published -
233
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Deubiquitylating enzyme USP9x regulates hippo pathway activity by controlling angiomotin protein turnover
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
222
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Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance
Research output: Contribution to journal › Journal article › Research › peer-review
Published