Jakob Nilsson
Professor
Nilsson Group
Blegdamsvej 3B
2200 København N
Jakob Nilsson is Associate Professor at Novo Nordisk Foundation Center for Protein Research, which he joined in 2011. Jakob did his PhD studies in the lab of Professor Jørgen Kjems, University of Aarhus, working on the small GTPase Ran. Following this, he joined Professor Poul Nissens Group, University of Aarhus, and studied structural aspects of the eukaryotic ribosome using cryo-EM. In 2005, he initiated his second Postdoc in the lab of Jonathon Pines at the Gurdon Institute, University of Cambridge, where he focused on understanding how cells accurately segregate their chromosomes during mitosis. In 2009, he was awarded the Lundbeck Foundation Junior Group Leader Fellowship to establish his own lab at BRIC, University of Copenhagen, focusing on mitotic regulation. In 2011, he moved to Novo Nordisk Foundation Center for Protein Research where he has continued his work on cell division.
Selected publications
- Published
A Consensus Binding Motif for the PP4 Protein Phosphatase
Ueki, Y., Kruse, Thomas, Weisser, Melanie, Sundell, G. N., Larsen, Marie Sofie Yoo, Mendez, B. L., Jenkins, N. P., Garvanska, Dimitriya Hristoforova, Cressey, L., Zhang, G., Davey, N., Montoya, Guillermo, Ivarsson, Y., Kettenbach, A. N. & Nilsson, Jakob, 2019, In: Molecular Cell. 76, 6, p. 953-964.e6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficient mitotic checkpoint signaling depends on integrated activities of Bub1 and the RZZ complex
Zhang, G., Kruse, Thomas, Guasch Boldú, C., Garvanska, Dimitriya Hristoforova, Coscia, F., Mann, Matthias, Barisic, Marin & Nilsson, Jakob, 2019, In: E M B O Journal. 38, 7, e100977.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Ebola Virus Nucleoprotein Recruits the Host PP2A-B56 Phosphatase to Activate Transcriptional Support Activity of VP30
Kruse, Thomas, Biedenkopf, N., Hertz, Emil Peter Thrane, Dietzel, E., Stalmann, G., López-Méndez, B., Davey, N. E., Nilsson, Jakob & Becker, S., 4 Jan 2018, In: Molecular Cell. 69, 1, p. 136-145 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling
Zhang, G., Kruse, Thomas, López-Méndez, B., Sylvestersen, K. B., Garvanska, Dimitriya Hristoforova, Schopper, S., Nielsen, Michael Lund & Nilsson, Jakob, 12 Jun 2017, In: Nature Communications. 8, 12 p., 15822.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distinct kinetics of serine and threonine dephosphorylation are essential for mitosis
Hein, J. B., Hertz, Emil Peter Thrane, Garvanska, Dimitriya Hristoforova, Kruse, Thomas & Nilsson, Jakob, 2017, In: Nature Cell Biology. 19, p. 1433-1440Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Conserved Motif Provides Binding Specificity to the PP2A-B56 Phosphatase
Hertz, Emil Peter Thrane, Kruse, Thomas, Davey, N. E., López-Méndez, B., Sigurdsson, J. O., Montoya, Guillermo, Olsen, Jesper Velgaard & Nilsson, Jakob, 2016, In: Molecular Cell. 63, 4, p. 686-695 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two functionally distinct kinetochore pools of BubR1 ensure accurate chromosome segregation
Zhang, G., Mendez, B. L., Sedgwick, G. G. & Nilsson, Jakob, 2016, In: Nature Communications. 7, p. 1-12 12 p., 12256.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 8799501
Most downloads
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164
downloads
Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
106
downloads
A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
103
downloads
Mechanisms of site-specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits
Research output: Contribution to journal › Journal article › Research › peer-review
Published