Michael Lisby
Professor
Functional Genomics
Ole Maaløes Vej 5
2200 København N.
The research of my laboratory is focused on the spatio-temporal organization and regulation of homologous recombination (HR) and its role in maintaining genome integrity. We take a cell biological and genetic approach to study HR in human cells and the yeast Saccharomyces cerevisiae. Particular areas of interest are regulation of chromatin structure during HR, post-translational modification of HR proteins and the molecular architecture of HR complexes in living cells. We are particularly interested in understanding molecular mechanisms relevant to cancer predisposition, neurological disorders and premature ageing syndromes, and in utilizing homologous recombination in CRISPR-Cas9 gene-editing.
For more information visit https://www1.bio.ku.dk/english/research/fg/dnarepair/
Follow @lisby_michael
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1586
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DNA damage response to eroded telomeres
Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic basis for Saccharomyces cerevisiae biofilm in liquid medium
Research output: Contribution to journal › Journal article › Research › peer-review
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970
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MRX protects fork integrity at protein-DNA barriers, and its absence causes checkpoint activation dependent on chromatin context
Research output: Contribution to journal › Journal article › Research › peer-review
Published