Lene Juel Rasmussen

Lene Juel Rasmussen

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  1. Published

    Mitochondria in health and disease: 3rd annual conference of society for mitochondrial research and medicine - 19-20 december 2013 - bengaluru, India

    Durhuus, J. A., Desler, Claus & Rasmussen, Lene Juel, Jan 2015, In: Mitochondrion. 20, p. 7-12 6 p.

    Research output: Contribution to journal › Conference article › Research › peer-review

  2. Published

    Mitochondria in biology and medicine--2012

    Desler, Claus & Rasmussen, Lene Juel, May 2014, In: Mitochondrion. 16, p. 2-6 5 p.

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    Mitochondria in biology and medicine

    Desler, Claus & Rasmussen, Lene Juel, Jul 2012, In: Mitochondrion. 12, 4, p. 472-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Mitochondria as determinant of nucleotide pools and chromosomal stability

    Desler, C., Munch-Petersen, B., Stevnsner, T., Matsui, S., Kulawiec, M., Singh, K. K. & Rasmussen, Lene Juel, 1 Dec 2007, In: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 625, 1-2, p. 112-24 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway-UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies

    Wang, H. L., Siow, R., Schmauck-Medina, T., Zhang, J., Sandset, P. M., Filshie, C., Lund, Ø., Partridge, L., Bergersen, L. H., Juel Rasmussen, L., Palikaras, K., Sotiropoulos, I., Storm-Mathisen, J., Rubinsztein, D. C., Spillantini, M. G., De Zeeuw, C. I., Watne, L. O., Vyhnalek, M., Veverova, K., Liang, K. X. & 18 others, Tavernarakis, N., Bohr, Vilhelm, Yokote, K., Saarela, J., Nilsen, H., Gonos, E. S., Scheibye-Knudsen, Morten, Chen, G., Kato, H., Selbæk, G., Fladby, T., Nilsson, P., Simonsen, A., Aarsland, D., Lautrup, S., Ottersen, O. P., Cox, L. S. & Fang, E. F., 2024, In: The journals of gerontology. Series A, Biological sciences and medical sciences. 79, 4, 10 p., glae029.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    MRE11A: a novel negative regulator of human DNA mismatch repair

    Du, D., Yang, Y., Wang, G., Chen, L., Guan, X., Rasmussen, Lene Juel & Liu, D., 2023, bioRxiv, 34 p.

    Research output: Working paper › Preprint

  7. Published

    MERTK Acts as a costimulatory receptor on human cd8 t cells

    Peeters, M. J. W., Dulkeviciute, D., Draghi, A., Ritter, C., Rahbech, A., Skadborg, S. K., Seremet, T., Simoes, A. M. C., Martinenaite, E., Halldorsdottir, H. R., Andersen, Mads Hald, Olofsson, G. H., Svane, Inge Marie, Rasmussen, Lene Juel, Met, Özcan, Becker, J. C., dqp123, dqp123, Desler, Claus & Straten, P. T., 2019, In: Cancer Immunology Research. 7, 9, p. 1472-1484 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    LIFESTAT – Living with statins: An interdisciplinary project on the use of statins as a cholesterol-lowering treatment and for cardiovascular risk reduction

    Christensen, Christa Lykke, Helge, Jørn Wulff, Krasnik, Allan, Kriegbaum, Margit, Rasmussen, Lene Juel, Hickson, Ian David, Liisberg, Kasper Bering, Oxlund, Bjarke, Bruun, B., Lau, Sofie Rosenlund, Olsen, M. N. A., Andersen, John Sahl, Heltberg, Andreas Søndergaard, Kuhlman, A. C. B., Morville, T. H., Dohlmann, T. L., Larsen, Steen & Dela, Flemming, 2016, In: Scandinavian Journal of Public Health. 44, 5, p. 534-539 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Is hEXO1 a cancer predisposing gene?

    Liberti, S. E. & Rasmussen, Lene Juel, Aug 2004, In: Molecular Cancer Research. 2, 8, p. 427-32 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Is There a Link between Mitochondrial Reserve Respiratory Capacity and Aging?

    Hansen, T. L., Rasmussen, Lene Juel, Desler, Claus, Frederiksen, J. B., Espersen, M. L. M. & Singh, K. K., 2012, In: Journal of Aging Research. 2012, p. 192503 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Involvement of the DNA mismatch repair system in cisplatin sensitivity of testicular germ cell tumours

    Rudolph, C., Melau, C., Nielsen, J. E., Jensen, K. V., Liu, D., Pena-Diaz, J., Meyts, E. R., Rasmussen, Lene Juel & Jorgensen, A., 2017, In: Cellular Oncology. 40, 4, p. 341-355

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Introducing the hypothome: a way to integrate predicted proteins in interactomes

    Desler, Claus, Zambach, S., Suravajhala, P. & Rasmussen, Lene Juel, 2014, In: International Journal of Bioinformatics Research and Applications. 10, 6, p. 647-52 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Interventions for age-related diseases: Shifting the paradigm

    Figueira, I., Fernandes, A., Mladenovic Djordjevic, A., Lopez-Contreras, Andres, Henriques, C. M., Selman, C., Ferreiro, E., Gonos, E. S., Trejo, J. L., Misra, J., Rasmussen, Lene Juel, Xapelli, S., Ellam, T. & Bellantuono, I., Dec 2016, In: Mechanisms of Ageing and Development. 160, p. 69-92 24 p.

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    Interactions between mitochondrial dysfunction and other hallmarks of aging: Paving a path toward interventions that promote healthy old age

    Li, Yuan, Berliocchi, Laura, Li, Zhiquan & Rasmussen, Lene Juel, 2024, In: Aging Cell. 23, 1, 12 p., e13942.

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    Interaction between RECQL4 and OGG1 promotes repair of oxidative base lesion 8-oxoG and is regulated by SIRT1 deacetylase

    Duan, S., Han, X., Akbari, M., Croteau, D. L., Rasmussen, Lene Juel & Bohr, Vilhelm, 2020, In: Nucleic Acids Research. 48, 12, p. 6530–6546

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Initial brain aging: heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus

    Thomsen, Kirsten Joan, Yokota, T., Hasan-Olive, M. M., Sherazi, N., Fakouri, N. B., Desler, Claus, Regnell, C. E., Larsen, S., Rasmussen, Lene Juel, Dela, Flemming, Bergersen, L. H. & Lauritzen, Martin, 2018, In: Neurobiology of Aging. 61, p. 215-224 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Information, involvement, self-care and support—The needs of caregivers of people with stroke: A grounded theory approach

    Lobo, E. H., Frølich, Anne, Abdelrazek, M., Rasmussen, Lene Juel, Grundy, J., Livingston, P. M., Islam, S. M. S. & Kensing, Finn, 2023, In: PLoS ONE. 18, 1, p. 1-25 25 p., e0281198.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Influence of Nodal signalling on pluripotency factor expression, tumour cell proliferation and cisplatin-sensitivity in testicular germ cell tumours

    Harpelunde Poulsen, K., Nielsen, J. E., Grønkær Toft, B., Joensen, Ulla Nordström, Rasmussen, Lene Juel, Blomberg Jensen, M., Mitchell, R. T., Juul, Anders, Rajpert-De Meyts, E. & Jørgensen, Anders, 2020, In: BMC Cancer. 20, 1, 14 p., 349.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Increased deoxythymidine triphosphate levels is a feature of relative cognitive decline

    Desler, Claus, Frederiksen, J. H., Olsen, M. N. A., Maynard, S., Keijzers, G., Fagerlund, Birgitte, Mortensen, Erik Lykke, Osler, Merete, Lauritzen, Martin, Bohr, Vilhelm & Rasmussen, Lene Juel, Nov 2015, In: Mitochondrion. 25, p. 34-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice

    Lopez-Contreras, Andres, Specks, J., Barlow, J. H., Ambrogio, C., Desler, Claus, Vikingsson, S., Rodrigo-Perez, S., Green, H., Rasmussen, Lene Juel, Murga, M., Nussenzweig, A. & Fernandez-Capetillo, O., 1 Apr 2015, In: Genes & Development. 29, 7, p. 690-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    In Silico screening for functional candidates amongst hypothetical proteins

    Desler, Claus, Suravajhala, P., Sanderhoff, M., Rasmussen, M. & Rasmussen, Lene Juel, 2009, In: BMC Bioinformatics. 10, p. 289

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure

    Lauritzen, K. H., Kleppa, L., Aronsen, J. M., Eide, L., Carlsen, H., Haugen, O. P., Sjaastad, I., Klungland, A., Rasmussen, Lene Juel, Attramadal, H., Storm-Mathisen, J. & Bergersen, L. H., 1 Aug 2015, In: American Journal of Physiology: Heart and Circulatory Physiology. 309, 3, p. H434-H449 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Impact of bacterial infections on aging and cancer: Impairment of DNA repair and mitochondrial function of host cells

    Strickertsson, J. A. B., Desler, Claus & Rasmussen, Lene Juel, Aug 2014, In: Experimental Gerontology. 56, p. 164-174 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Human exonuclease 1 (EXO1) activity characterization and its function on FLAP structures

    Keijzers, G., Bohr, Vilhelm & Rasmussen, Lene Juel, 2015, In: Bioscience Reports. 35, 3, 13 p., e00206.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Human DNA polymerase delta double-mutant D316A;E318A interferes with DNA mismatch repair in vitro

    Liu, D., Frederiksen, J. H., Liberti, S. E., Lützen, Anne Hoff Kjeldsen, Keijzers, G., Pena-Diaz, J. & Rasmussen, Lene Juel, 19 Sep 2017, In: Nucleic Acids Research. 45, 16, p. 9427-9440 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Heterogeneity of ductular reactions in adult rat and human liver revealed by novel expression of deleted in malignant brain tumor

    Bisgaard, Hanne Cathrine, Holmskov, U., Santoni Rugiu, Eric, Nagy, P., Nielsen, O., Ott, P., Hage, E., Dalhoff, Kim, Rasmussen, Lene Juel & Tygstrup, N., 2002, In: American Journal of Pathology. 161, 4, p. 1187-1198 12 p., 64395.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Heterogeneity of ductular reactions in adult rat and human liver revealed by novel expression of deleted in malignant brain tumor

    Bisgaard, Hanne Cathrine, Holmskov, U., Santoni Rugiu, Eric, Nagy, P., Nielsen, O., Ott, P., Hage, E., Dalhoff, Kim, Rasmussen, Lene Juel & Tygstrup, N., 2002, In: American Journal of Pathology. 161, 4, p. 1187-1198 12 p., 64395.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Helicobacter pylori infection induces genetic instability of nuclear and mitochondrial DNA in gastric cells

    Machado, A. M. D., Figueiredo, C., Touati, E., Máximo, V., Sousa, S., Michel, V., Carneiro, F., Nielsen, Finn Cilius, Seruca, R. & Rasmussen, Lene Juel, 2009, In: Clinical Cancer Research. 15, 9, p. 2995-3002 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Helicobacter pylori infection generates genetic instability in gastric cells

    Machado, A. M. D., Figueiredo, C., Seruca, R. & Rasmussen, Lene Juel, 2010, In: BBA General Subjects. 1806, 1, p. 58-65 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Growth-rate-dependent transcription initiation from the dam P2 promoter

    Rasmussen, Lene Juel, Løbner-Olesen, Anders & Marinus, M. G., 1995, In: Gene. 157, 1-2, p. 213-215 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Genomic instability and aging

    Li, Zhiquan, Anugula, Sharath & Rasmussen, Lene Juel, 2022, Aging: From Fundamental Biology to Societal Impact. Oliveira, P. J. & Malva, J. O. (eds.). Academic Press, p. 275-295 21 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  32. Published

    Genomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions

    Martín-Pardillos, A., Tsaalbi-Shtylik, A., Chen, S., Lazare, S., Van Os, R. P., Dethmers-Ausema, A., Fakouri, N. B., Bosshard, M., Aprigliano, R., Van Loon, B., Salvatori, D. C. F., Hashimoto, K., Van Der Spek, C. D., Moriya, M., Rasmussen, Lene Juel, De Haan, G., Raaijmakers, M. H. G. P. & De Wind, N., 2017, In: Blood. 130, 13, p. 1523-1534 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Genome-wide screens for expressed hypothetical proteins

    Desler, Claus, Durhuus, J. A. & Rasmussen, Lene Juel, 2012, In: Methods in molecular biology (Clifton, N.J.). 815, p. 25-38 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Genetic screens to identify pathogenic gene variants in the common cancer predisposition Lynch syndrome

    Drost, M., Lützen, A., van Hees, S., Ferreira, D., Calléja, F., Zonneveld, J. B. M., Nielsen, Finn Cilius, Rasmussen, Lene Juel & de Wind, N., 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 23, p. 9403-9408 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Genetic screens to identify pathogenic gene variants in the common cancer predisposition Lynch syndrome

    Drost, M., Lützen, A., van Hees, S., Ferreira, D., Calléja, F., Zonneveld, J. B. M., Nielsen, Finn Cilius, Rasmussen, Lene Juel & de Wind, N., 4 Jun 2013, In: Proceedings of the National Academy of Science of the United States of America. 110, 23, p. 9403-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Galectin-7 reprograms skin carcinogenesis by fostering innate immune evasive programs

    Pinto, N. A., Abba, M. C., Laporte, L., Pérez Sáez, J. M., Blidner, A. G., Torres, N. I., Morales, R. M., Gatto, S. G., Bach, C. A., Veigas, F., García Rivello, H. J., Song, P., Frederiksen, J. H., Rasmussen, Lene Juel, Poirier, F., Croci, D. O., Sundblad, V., Rabinovich, G. A. & Cerliani, J. P., 2023, In: Cell Death and Differentiation. 30, p. pages906–921

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Functional implications of the p.Cys680Arg mutation in the MLH1 mismatch repair protein

    Dominguez-Valentin, M., Drost, M., Therkildsen, C., Rambech, E., Ehrencrona, H., Angleys, M., Lau Hansen, T., de Wind, N., Nilbert, Mef Christina & Rasmussen, Lene Juel, Jul 2014, In: Molecular Genetics & Genomic Medicine. 2, 4, p. 352-355 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Functional examination of MLH1, MSH2, and MSH6 intronic mutations identified in Danish colorectal cancer patients

    Petersen, S. M., Dandanell, M., Rasmussen, Lene Juel, Gerdes, Anne-Marie Axø, Krogh, L. N., Bernstein, I., Okkels, H., Wikman, F., Nielsen, Finn Cilius & Hansen, Thomas van Overeem, 2013, In: BMC Medical Genetics. 14, p. 103

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Functional characterization of MLH1 missense variants identified in Lynch Syndrome patients

    Andersen, S. D., Liberti, S. E., Lützen, A., Drost, M., Bernstein, I., Nilbert, Mef Christina, Dominguez, M., Nyström, M., Hansen, Thomas van Overeem, Christoffersen, J. W., Jäger, A. C., de Wind, N., Nielsen, Finn Cilius, Tørring, P. M. & Rasmussen, Lene Juel, Dec 2012, In: Human Mutation. 33, 12, p. 1647-1655 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Functional analysis of HNPCC-related missense mutations in MSH2

    Lützen, A., de Wind, N., Georgijevic, D., Nielsen, Finn Cilius & Rasmussen, Lene Juel, 14 Oct 2008, In: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 645, 1-2, p. 44-55 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    From powerhouse to perpetrator—mitochondria in health and disease

    Fakouri, N. B., Hansen, T. L., Desler, Claus, Anugula, Sharath & Rasmussen, Lene Juel, 2019, In: Biology. 8, 2, 15 p., 35.

    Research output: Contribution to journal › Review › Research › peer-review

  42. Published

    Exonuclease 1 and its versatile roles in DNA repair

    Keijzers, G., Liu, D. & Rasmussen, Lene Juel, 5 Aug 2016, In: Critical Reviews in Biochemistry and Molecular Biology. 51, 6, p. 440–451 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  43. Published

    Enterococcus faecalis infection causes inflammation, intracellular oxphos-independent ROS production, and DNA damage in human gastric cancer cells

    Strickertsson, J. A. B., Desler, Claus, Martin-Bertelsen, T., Machado, A. M. D., Wadstrøm, T., Winther, Ole, Rasmussen, Lene Juel & Friis-Hansen, Lennart Jan, 2013, In: PLOS ONE. 8, 4, p. 1-13 13 p., e63147.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Enterococcus faecalis Infection and Reactive Oxygen Species Down-Regulates the miR-17-92 Cluster in Gastric Adenocarcinoma Cell Culture

    Strickertsson, J. A. B., Rasmussen, Lene Juel & Friis-Hansen, Lennart Jan, 28 Aug 2014, In: Genes. 5, 3, p. 726-38 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Effects of reactive oxygen species and mitochondrial dysfunction on reproductive aging

    Song, J., Xiao, L., Zhang, Z., Wang, Y., Kouis, P., Rasmussen, Lene Juel & Dai, F., 2024, In: Frontiers in Cell and Developmental Biology. 12, 12 p., 1347286.

    Research output: Contribution to journal › Review › Research › peer-review

  46. Published

    EXO1 (Exonuclease 1)

    Rasmussen, Lene Juel & Keijzers, G., 5 Jan 2017, Encyclopedia of Signaling Molecules . Choi, S. (ed.). New York: Springer, 7 p.

    Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Research

  47. Published

    EX-vivo whole blood stimulation with A2E does not elicit an inflammatory cytokine response in patients with age-related macular degeneration

    Durhuus, J. A., Rozing, Maarten Pieter, Nielsen, M. K., Molbech, C. R., Keijzers, G., Scheibye-Knudsen, Morten, Rasmussen, Lene Juel, Westendorp, Rudi GJ & Sørensen, Torben Lykke, 2021, In: Scientific Reports. 11, 1, 8226.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Dynamics of the DNA repair proteins WRN and BLM in the nucleoplasm and nucleoli

    Bendtsen, K. M., Jensen, M. B., May, A., Rasmussen, Lene Juel, Trusina, Ala, Bohr, Vilhelm & Jensen, Mogens Høgh, 14 Nov 2014, In: European Biophysics Journal. 43, 10-11, p. 509-516

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Disturbed mitochondrial function restricts glutamate uptake in the human Müller glia cell line, MIO-M1

    Vohra, Rupali, Gurubaran, I. S., Henriksen, U., Bergersen, L. H., Rasmussen, Lene Juel, Desler, C., Jensen, Dorte Skytt & Kolko, Miriam, 2017, In: Mitochondrion. 36, p. 52-59

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Differential expression of hMLH1 in sporadic human colorectal cancer tumors and distant metastases

    Larsen, N. B., Heiberg Engel, P. J., Rasmussen, M. & Rasmussen, Lene Juel, 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 11, p. 839-48 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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