Sten Madsbad
Clinical Professor
Department of Clinical Medicine
Kettegård Allé 30, 2650 Hvidovre
Member of:
Internal Medicine: Endocrinology
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Ætiologi og patogenese, type 2 diabetes
Madsbad, Sten, 2011, Diabetes - sygdom, behandling og organisation. Hilsted, J., Borch-Johansen, K. & Christiansen, J. S. (eds.). Munksgaard , p. 97-107Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
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Young, low-birth-weight men are not more susceptible to the diabetogenic effects of a prolonged free fatty acid exposure than matched controls.
Jensen, C. B., Storgaard, H., Holst, Jens Juul, Dela, Flemming, Madsbad, Sten & Vaag, Allan, 2005, In: Metabolism - Clinical and Experimental. 54, 10, p. 1398-406 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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What is Diabetes Remission?
Holst, Jens Juul & Madsbad, Sten, 2021, In: Diabetes Therapy. 12, p. 641-646 6 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Weight loss maintenance with exercise and liraglutide improves glucose tolerance, glucagon response, and beta cell function
Jensen, Simon Birk Kjær, Juhl, C. R., Janus, C., Lundgren, J. R., Martinussen, C., Wiingaard, C., Knudsen, C., Frikke-Schmidt, Ruth, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2023, In: Obesity. 31, 4, p. 977-989 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Weight-loss induced by carbohydrate restriction does not negatively affect health-related quality of life and cognition in people with type 2 diabetes: A randomised controlled trial
Jensen, N. J., Wodschow, H. Z., Skytte, M. J., Samkani, A., Astrup, A., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Miskowiak, Kamilla, Haugaard, Steen Bendix, Krarup, T., Rungby, Jørgen & Thomsen, M. N., 2022, In: Clinical Nutrition. 41, 7, p. 1605-1612 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Weight loss-induced improvements of endothelial function and cardiovascular risk factors are maintained with exercise, liraglutide or the combination
Lundgren, J. R., Bladbjerg, E. M., Janus, C., Gliemann, Lasse, Olsen, L. M., Juhl, C. R., Jensen, Simon Birk Kjær, Thirumathyam, R., Stallknecht, Bente Merete, Holst, Jens Juul, Hove, Jens Dahlgaard, Madsbad, Sten, Antoinades, C. & Torekov, Signe Sørensen, 2020, In: Diabetologia. 63, SUPPL 1, p. S457-S457 1 p., 959.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Weight loss improves β-cell function independently of dietary carbohydrate restriction in people with type 2 diabetes: A 6-week randomized controlled trial
Thomsen, M. N., Skytte, M. J., Samkani, A., Astrup, A., Fenger, M., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Rehfeld, Jens Frederik, Haugaard, Steen Bendix & Krarup, T., 2022, In: Frontiers in Nutrition. 9, 14 p., 933118.Research output: Contribution to journal › Journal article › Research › peer-review
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Weight loss and weight maintenance obtained with or without GLP-1 analogue treatment decrease branched chain amino acid levels
pjx571, pjx571, Iepsen, E. P. W., Galijatovic, E. A. A., Mahendran, Y., Lundgren, J. R., Jonsson, Anna Elisabet, Madsbad, Sten, Holst, Jens Juul, drb459, drb459, Hansen, Torben & Torekov, Signe Sørensen, Dec 2016, In: Metabolomics. 12, 12, p. 1-9 9 p., 181.Research output: Contribution to journal › Journal article › Research › peer-review
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Variable reliability of surrogate measures of insulin sensitivity after Roux-en-Y gastric bypass
Bojsen-Møller, K. N., Dirksen, C., Svane, M. S., Jørgensen, N. B., Holst, Jens Juul, Richter, Erik A. & Madsbad, Sten, 2017, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 312, 5, p. R797-R805 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Validation of methods for measurement of insulin secretion in humans in vivo.
Kjems, L. L., Christiansen, E., Vølund, A., Bergman, R. N. & Madsbad, Sten, 2000, In: Diabetes. 49, 4, p. 580-588 9 p.Research output: Contribution to journal › Journal article › Research
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Updates in weight loss surgery and gastrointestinal peptides
Svane, M. S., Bojsen-Møller, K. N., Madsbad, Sten & Holst, Jens Juul, Feb 2015, In: Current Opinion in Endocrinology, Diabetes and Obesity. 22, 1, p. 21-8 8 p.Research output: Contribution to journal › Review › Research › peer-review
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Unprecedented high insulin secretion in a healthy human subject after intravenous glucagon-like peptide-1: a case report
Knop, Filip Krag, Lund, Asger Bach, Madsbad, Sten, Holst, Jens Juul, Krarup, T. & Vilsbøll, T., 2014, In: BMC Research Notes. 7, p. 1-6 6 p., 326.Research output: Contribution to journal › Journal article › Research › peer-review
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Under-reporting of adverse effects of tesofensine
Astrup, A., Madsbad, Sten, Breum, Leif, Jensen, T. J., Kroustrup, J. P. & Larsen, T. M., 2013, In: Lancet. 382, 9887, p. 127 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Udfordringer for perioperativ glykæmisk kontrol hos patienter med diabetes
Madsbad, Sten, Wiberg, M., Issa, L. M., Schmidt, S. & Kehlet, Henrik, 17 Oct 2022, In: Ugeskrift for Laeger. 184, 42, 9 p., V05220321.Research output: Contribution to journal › Review › Research › peer-review
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Type 2-diabetes--et sammenhængende sundhedsvæsen efterlyses
Madsbad, Sten, 2012, In: Ugeskrift for Laeger. 174, 37, p. 2131Research output: Contribution to journal › Journal article › Research › peer-review
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Type 2 diabetes: which drug as add-on to metformin?
Madsbad, Sten, 2012, In: Lancet. 379, 9833, p. 2222-3 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Twelve-Week Treatment With Liraglutide as Add-on to Insulin in Normal-Weight Patients With Poorly Controlled Type 1 Diabetes: A Randomized, Placebo-Controlled, Double-Blind Parallel Study
Frandsen, C. S., Dejgaard, T. F., Holst, Jens Juul, Andersen, H. U., Thorsteinsson, B. & Madsbad, Sten, Dec 2015, In: Diabetes Care. 38, 12, p. 2250-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose- and non-glucose-induced insulin secretion in patients with type 2 diabetes mellitus
Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2010, In: Diabetes, Obesity and Metabolism. 12, 4, p. 323-333 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Twelve weeks treatment with the DPP-4 inhibitor sitagliptin improves glycaemic control, but does not improve GLP-1 secretion, in patients with type 2 diabetes - a randomised trial
Aaboe, K., Knop, F. K., Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2009, In: Diabetologia. p. 748Research output: Contribution to journal › Conference abstract in journal › Research
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Tumor necrosis factor alpha is associated with insulin-mediated suppression of free fatty acids and net lipid oxidation in HIV-infected patients with lipodystrophy
Haugaard, S. B., Andersen, Ove, Pedersen, S., Dela, Flemming, Fenger, M., Richelsen, B., Madsbad, Sten, Iversen, J. & Pedersen, E. S., 2006, In: Metabolism - Clinical and Experimental. 55, 2, p. 175-82 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Treatment with liraglutide may improve markers of CVD reflected by reduced levels of apoB
pjx571, pjx571, Lundgren, Jens, Albrechtsen, Nicolai Jacob Wewer, Mahendran, Y., Iepsen, E. P. W., Finocchietto, P., Jonsson, Anna Elisabet, Madsbad, Sten, Holst, Jens Juul, drb459, drb459, Hansen, Torben & Torekov, Signe Sørensen, 2017, In: Obesity Science & Practice. 3, 4, p. 425-433 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Treatment with a GLP-1 receptor agonist diminishes the decrease in free plasma leptin during maintenance of weight loss
Iepsen, E. W., Lundgren, J., Dirksen, C., Jensen, J., Pedersen, Oluf Borbye, Hansen, Torben, Madsbad, Sten, Holst, Jens Juul & Torekov, Signe Sørensen, 2015, In: International journal of obesity (2005). 39, 5, p. 834-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Treatment with GLP-1 Receptor Agonists
Madsbad, Sten & Holst, Jens Juul, 2018, Diabetes: Epidemiology, Genetics, Pathogenesis, Diagnosis, Prevention, and Treatment. Bonora, E. & DeFronzo, R. (eds.). Springer, 45 p. (Endocrinology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Treatment potential of the GLP-1 receptor agonists in type 2 diabetes mellitus: a review
Østergaard, L., Frandsen, C. S. & Madsbad, Sten, 2016, In: Expert Review of Clinical Pharmacology. 9, 2, p. 241-65 25 p.Research output: Contribution to journal › Review › Research › peer-review
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Treatment of type 2 diabetes with incretin-based therapies
Madsbad, Sten, 2008, In: Lancet. 373, 9662, p. 438-9Research output: Contribution to journal › Journal article › Research › peer-review
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Treatment of type 1 diabetic patients with glucagon-like peptide-1 (GLP-1) and GLP-1R agonists
Kielgast, U., Holst, Jens Juul & Madsbad, Sten, Nov 2009, In: Current Diabetes Reviews. 5, 4, p. 266-75 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Treatment of type 1 diabetic patients with glucagon-like peptide-1 (GLP-1) and GLP-1R agonists
Kielgast, U., Holst, J., Madsbad, Sten, Kielgast, U., Holst, J. J. & Madsbad, Sten, 2009, In: Current Diabetes Reviews. 5, 4, p. 266-75 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The role of glucagon-like peptide-1 impairment in obesity and potential therapeutic implications
Madsbad, Sten, Jan 2014, In: Diabetes, Obesity and Metabolism. 16, 1, p. 9-21 13 p.Research output: Contribution to journal › Review › Research › peer-review
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The role of empagliflozin-induced metabolic changes for cardiac function in patients with type 2 diabetes. A randomized cross-over magnetic resonance imaging study with insulin as comparator
Thirumathyam, R., Richter, Erik A., van Hall, Gerrit, Holst, Jens Juul, Fenger, M., Goetze, Jens P. , Dixen, Ulrik, Vejlstrup, N., Madsbad, Sten, Madsen, Per & Jørgensen, N. B., 2024, In: Cardiovascular Diabetology. 23, 1, p. 1-13 13.Research output: Contribution to journal › Journal article › Research › peer-review
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The role of GLP-1 in postprandial glucose metabolism after bariatric surgery: a narrative review of human GLP-1 receptor antagonist studies
Hindsø, M., Svane, M. S., Hedbäck, N., Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2021, In: Surgery for Obesity and Related Diseases. 17, 7, p. 1383-1391Research output: Contribution to journal › Review › Research › peer-review
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The proposed terminology 'A(1c)-derived average glucose' is inherently imprecise and should not be adopted. Reply to Bloomgarden ZT, Inzucchi SE, Karnieli E, et al. [letter]
Haugaard, S. B., Madsbad, Sten & Mølvig, J., 2008, In: Diabetologia. 52, 3, p. 547-49Research output: Contribution to journal › Journal article › Research › peer-review
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The prevalence of metabolic syndrome in Danish patients with HIV infection: the effect of antiretroviral therapy
Hansen, B. R., Petersen, J., Haugaard, Steen Bendix, Madsbad, Sten, Obel, Niels, Suzuki, Y., Andersen, O., Hansen, B. R., Petersen, J., Haugaard, S. B., Madsbad, Sten, Obel, N., Suzuki, Y. & Andersen, Ove, 2009, In: HIV Medicine. 10, 6, p. 378-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The prevalence of comorbidities in Danish patients with obesity – A Danish register-based study based on data from 2002 to 2018
Pedersen, M. H., Bøgelund, M., Dirksen, Carsten Moro, Johansen, P., Jørgensen, Nils Bruun, Madsbad, Sten & Pantin, U. H., 2022, In: Clinical obesity. 12, 5, e12542.Research output: Contribution to journal › Journal article › Research › peer-review
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The pathophysiology of diabetes involves a defective amplification of the late-phase insulin response to glucose by glucose-dependent insulinotropic polypeptide-regardless of etiology and phenotype
Vilsbøll, Tina, Knop, Filip Krag, Krarup, T., Johansen, A., Madsbad, Sten, Larsen, S., Hansen, T., Pedersen, O., Holst, J. M. & Johansen, A., 1 Oct 2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 10, p. 4897-903 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose leves in patients with type 2 diabetes.
Zander, M., Madsbad, Sten, Deacon, C. & Holst, J., 2006, In: Diabetologia. 49, p. 369-374 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes
Zander, M., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, Feb 2006, In: Diabetologia. 49, 2, p. 369-74 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The long-term effect of tesofensine on weight loss: interim results from a one-armed, open-labelled extension study
Sjödin, Anders Mikael, Madsbad, Sten, Breum, Leif, Kroustrup, J. P., Raben, Anne, Jensen, J. K. S., Meier, D. & Astrup, A., 2009, In: Obesity. 17, Suppl. 2, p. S107 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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The insulinotropic effect of GIP is impaired in patients with chronic pancreatitis and secondary diabetes mellitus as compared to patients with chronic pancreatitis and normal glucose tolerance.
Knop, F. K., Vilsbøll, Tina, Højberg, P. V., Larsen, S., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2007, In: Regulatory Peptides. 144, 1-3, p. 123-30 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The insulin-resistant phenotype of polycystic ovary syndrome
Svendsen, P. F., Madsbad, Sten & Nilas, L., 2009, In: Fertility and Sterility. 94, 3, p. 1052-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects.
Kjems, L. L., Holst, J. J., Vølund, A. & Madsbad, Sten, 2003, In: Diabetes. 52, 2, p. 380-386 7 p.Research output: Contribution to journal › Journal article › Research
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The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects
Kjems, L. L., Holst, Jens Juul, Vølund, A. & Madsbad, Sten, Feb 2003, In: Diabetes. 52, 2, p. 380-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The importance of endogenously secreted GLP-1 and GIP for postprandial glucose tolerance and β-cell function after Roux-en-Y gastric bypass and sleeve gastrectomy surgery
Hindsø, M., Hedbäck, N., Svane, M. S., Møller, A., Martinussen, C., Jørgensen, N. B., Dirksen, C., Gasbjerg, Lærke Smidt, Kristiansen, V. B., Hartmann, Bolette, Rosenkilde, Mette, Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: Diabetes. 72, 3, p. 336–347Research output: Contribution to journal › Journal article › Research › peer-review
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The impact of gastric bypass surgery on sex hormones and menstrual cycles in premenopausal women
Kjær, M. M., Madsbad, Sten, Hougaard, D. M., Cohen, A. S. & Nilas, L., 2017, In: Gynecological Endocrinology. 33, 2, p. 160-163 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The immune marker soluble urokinase plasminogen activator receptor is associated with new-onset diabetes in non-smoking women and men
Haugaard, S. B., Andersen, Ove, Hansen, T. W., Eugen-Olsen, J., Linneberg, Allan René, Madsbad, Sten, Olsen, M. H., Jørgensen, T., Borch-Johnsen, K. & Jeppesen, J., 2012, In: Diabetic Medicine. 29, 4, p. 479-487Research output: Contribution to journal › Journal article › Research › peer-review
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The exaggerated glucagon-like peptide-1 response is important for the improved β-cell function and glucose tolerance after Roux-en-Y gastric bypass in patients with type 2 diabetes
Jørgensen, N. B., Dirksen, C., Bojsen-Møller, K. N., Jacobsen, S. H., Worm, Dorte, Hansen, D. L., Kristiansen, V. B., Naver, L., Madsbad, Sten & Holst, Jens Juul, 6 May 2013, In: Diabetes. 62, 9, p. 3044-3052 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The elimination rates of intact GIP as well as its primary metabolite, GIP 3-42, are similar in type 2 diabetic patients and healthy subjects.
Vilsbøll, Tina, Agersø, H., Lauritsen, T., Deacon, Carolyn F., Aaboe, K., Madsbad, Sten, Krarup, T. & Holst, Jens Juul, 2006, In: Regulatory Peptides. 137, 3, p. 168-72 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effects of postprandial exercise and meal glycemic index on plasma glucose and glucoregulatory hormone responses after Roux-en-Y gastric bypass
Ternhamar, T., Møller, A., Martinussen, C., Svane, M. S., Hindsø, M., Jørgensen, N. B., Dirksen, C., Jensen, Jens-Erik Beck, Hartmann, Bolette, Holst, Jens Juul, Kiens, Bente, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: American journal of physiology. Endocrinology and metabolism. 325, 5, p. E540-E551 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of the deterioration of insulin sensitivity on beta-cell function in growth-hormone-deficient adults following 4-month growth hormone replacement therapy.
Rosenfalck, A. M., Fisker, S., Hilsted, J., Dinesen, B., Vølund, A., Jørgensen, J. O., Christiansen, J. S. & Madsbad, Sten, 1999, In: Growth Hormone & IGF Research. 9, 2, p. 96-105 10 p.Research output: Contribution to journal › Journal article › Research
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The effect of tesofensine on weight loss: results from a one-armed, open-labelled extension study
Astrup, A., Madsbad, Sten, Breum, Leif, Kroustrup, J. P., Raben, A., Jensen, J. K. S., Meier, D. & Sjödin, Anders Mikael, 2009, In: Obesity Facts. suppl. 2, p. 211-212 2 p.Research output: Contribution to journal › Conference abstract in journal › Research
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The effect of metformin versus placebo in combination with insulin analogues on bone mineral density and trabecular bone score in patients with type 2 diabetes mellitus: a randomized placebo-controlled trial
Nordklint, A. K., Almdal, Thomas Peter, Vestergaard, P., Lundby-Christensen, L., Boesgaard, T. W., Breum, Leif, Gade-Rasmussen, B., Sneppen, S. B., Gluud, C., Hemmingsen, B., Jensen, T., Krarup, T., Madsbad, Sten, Mathiesen, Elisabeth, Perrild, Hans, Tarnow, L., Thorsteinsson, B., drb459, drb459, Lund, S. S. & Eiken, P., 2018, In: Osteoporosis International. 29, 11, p. 2517-2526Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of intense exercise on postprandial glucose homeostasis in Type II diabetic patients
Larsen, J. J., Dela, Flemming, Madsbad, Sten & Galbo, Henrik, 1999, In: Diabetologia. 42, p. 1282-1292Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of glucagon-like peptide I (GLP-I) on glucose elimination in healthy subjects depends on the pancreatic glucoregulatory hormones.
Toft-Nielson, M., Madsbad, Sten & Holst, J. J., 1996, In: Diabetes. 45, 5, p. 552-556 5 p.Research output: Contribution to journal › Journal article › Research
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The effect of dietary carbohydrate restriction beyond weight loss on health-related quality of life and cognition
Jensen, N. J., Wodschow, H. Z., fbg982, fbg982, Samkani, A., Astrup, A., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Miskowiak, Kamilla, Rungby, Jørgen, Haugaard, Steen Bendix & Thomsen, M. N., 2021, In: Diabetologia. 64, SUPPL 1, p. 62-63 114.Research output: Contribution to journal › Conference abstract in journal › Research
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The effect of acute dual SGLT1/SGLT2 inhibition on incretin release and glucose metabolism after gastric bypass surgery
Martinussen, C., Veedfald, Simon, Dirksen, Carsten Moro, Bojsen-Møller, K. N., Svane, M. S., Albrechtsen, Nicolai Jacob Wewer, van Hall, Gerrit, Kristiansen, V. B., Fenger, M., Holst, Jens Juul & Madsbad, Sten, 2020, In: American Journal of Physiology: Endocrinology and Metabolism. 318, 6, p. E956-E964 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of a very low calorie diet on insulin sensitivity, beta cell function, insulin clearance, incretin hormone secretion, androgen levels and body composition in obese young women
Svendsen, P. F., Jensen, F. K., Holst, Jens Juul, Haugaard, Steen Bendix, Nilas, L. & Madsbad, Sten, Sep 2012, In: Scandinavian Journal of Clinical & Laboratory Investigation. 72, 5, p. 410-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of Roux-en-Y gastric bypass surgery on energy expenditure and appetite: a randomized human study including “pair fed” control subjects
Schmidt, J. B., Gregersen, N. T., Pedersen, S., Nielsen, M. S., Nielsen, L. V., Holst, Jens Juul, Hansen, D. L., Dorm, D. W., Madsbad, Sten, Clausen, T. R. C., Ritz, C., Astrup, A. & Sjödin, Anders Mikael, 2013, In: Obesity Facts. 6, suppl. 1, p. 28 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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The effect of DPP-4-protected GLP-1 (7-36) on coronary microvascular function in obese adults
Nilsson, M., Bové, K. B., Suhrs, E., Hermann, T., Madsbad, Sten, Holst, Jens Juul, Prescott, Eva & Zander, M., Mar 2019, In: IJC Heart and Vasculature. 22, p. 139-144Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of DPP-4 protected GLP-1 (7-36) on coronary microcirculation in obese adults
Nilsson, M., Bove, K., Suhrs, E., Hermann, T., Madsbad, Sten, Holst, Jens Juul, Prescott, Eva & Zander, M., 2018, In: Diabetologia. 61, S1, p. S354-S355 729.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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The effect of 30 months of low-dose replacement therapy with recombinant human growth hormone (rhGH) on insulin and C-peptide kinetics, insulin secretion, insulin sensitivity, glucose effectiveness, and body composition in GH-deficient adults.
Rosenfalck, A. M., Maghsoudi, S., Fisker, S., Jørgensen, J. O., Christiansen, J. S., Hilsted, J., Vølund, A. A. & Madsbad, Sten, 2000, In: Journal of Clinical Endocrinology and Metabolism. 85, 11, p. 4173-4181 9 p.Research output: Contribution to journal › Journal article › Research
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The clinical effects of a carbohydrate-reduced high-protein diet on glycaemic variability in metformin-treated patients with type 2 diabetes mellitus: A randomised controlled study
Thomsen, M. N., fbg982, fbg982, Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Krarup, T., Haugaard, Steen Bendix & Samkani, A., 2020, In: Clinical Nutrition ESPEN. 39, p. 46-52 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The antiresorptive effect of GIP, but not GLP-2, is preserved in patients with hypoparathyroidism - a randomized crossover study
Skov-Jeppesen, Kirsa, Hepp, N., Oeke, J., Hansen, M. S., Jafari Kermani, Abbas, Svane, M. S., Balenga, N., Olson, J. A., Frost, M., Kassem, Moustapha Saad El-Deen, Madsbad, Sten, Jensen, Jens-Erik Beck, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2021, In: Journal of Bone and Mineral Research. 36, 8, p. 1448-1458 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men
Pilgaard, K., Jensen, C., Schou, J., Lyssenko, V., Wegner, L., Brøns, C., Vilsbøll, T., Hansen, T., Madsbad, S., Holst, J., Vølund, A., Poulsen, P., Groop, L., Pedersen, O., Vaag, A., Pilgaard, K., Jensen, C. B., Schou, J. H., Lyssenko, V., Wegner, L. & 10 others, , 1 Jul 2009, In: Diabetologia. 52, 7, p. 1298-307 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Renal Extraction and the Natriuretic Action of GLP-1 in Humans Depend on Interaction With the GLP-1 Receptor
Asmar, A., Cramon, P. K., Asmar, M., Simonsen, L., Sorensen, Charlotte Mehlin, Madsbad, Sten, Hartmann, Bolette, Holst, Jens Juul, Hovind, P., Jensen, B. L. & Bülow, J., 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 1, p. e11-e19 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Impact of Nocturnal Hypoglycemia on Sleep in Subjects With Type 2 Diabetes
Jennum, Poul, Stender-Petersen, K., Rabøl, R., Jørgensen, Niklas Rye, Chu, P. & Madsbad, Sten, Nov 2015, In: Diabetes Care. 38, 11, p. 2151-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes
Sparsø, T., Andersen, G., Nielsen, T., Burgdorf, K. S., Gjesing, A. M. P., Nielsen, A. L., Albrechtsen, Anders, Rasmussen, S. S., Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Madsbad, Sten, Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Diabetologia. 51, 1, p. 70-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Effect of Bariatric Surgery on Healthcare Costs and Labor Market Attachment
Bogelund, M., Jørgensen, Nils Bruun, Madsbad, Sten, Spanggaard, M., Panton, U. H., Pedersen, M. H. & Johansen, P., Apr 2022, In: Obesity Surgery. 32, 4, p. 998-1004 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tesofensine and weight loss - Authors' reply
Astrup, A., Madsbad, Sten & Larsen, T. M., 26 Feb 2009, In: Lancet. 373, 9665, p. 720 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Tesofensine and weight loss: author's reply
Astrup, A., Madsbad, Sten & Larsen, T. M., 2009, In: Lancet. 373, 9665, p. 720 1 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Systems signatures reveal unique remission-path of Type 2 diabetes following Roux-en-Y gastric bypass surgery
Li, Q-R., Wang, Z-M., Albrechtsen, N. J. W., Wang, D-D., Su, Z-D., Gao, X-F., Wu, Q-Q., Zhang, H-P., Zhu, L., Li, R-X., Jacobsen, S., Jørgensen, N. B., Dirksen, C., Bojsen-Møller, K. N., Petersen, J. S., Madsbad, S., Clausen, T. R., Diderichsen, B., Chen, L-N., Holst, J. J. & 2 others, , 2018, In: EBioMedicine. 28, p. 234-240 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Switching between GLP‐1 receptor agonists in clinical practice: Expert consensus and practical guidance
Jain, A. B., Ali, A., Gorgojo Martínez, J. J., Hramiak, I., Kavia, K., Madsbad, Sten, Potier, L., Prohaska, B. D., Strong, J. L. & Vilsbøll, Tina, 1 Feb 2021, In: International Journal of Clinical Practice. 75, 2, 14 p., e13731.Research output: Contribution to journal › Review › Research › peer-review
- Published
Sustained low-dose growth hormone therapy optimizes bioactive insulin-like growth factor-I level and may enhance CD4 T-cell number in HIV infection
Andersen, Ove, Hansen, B. R., Troensegaard, W., Flyvbjerg, A., Madsbad, Sten, Ørskov, H., Nielsen, J. O., Iversen, J. & Haugaard, S. B., 2010, In: Journal of Medical Virology. 82, 2, p. 197-205 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sustained Improvements in Glucose Metabolism Late After Roux-En-Y Gastric Bypass Surgery in Patients with and Without Preoperative Diabetes
Jørgensen, N. B., Bojsen-Møller, K. N., Dirksen, C., Martinussen, C., Svane, M. S., Kristiansen, V. B., Holst, Jens Juul & Madsbad, Sten, 2019, In: Scientific Reports. 9, 1, 10 p., 15154.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Successful weight loss maintenance includes long-term increased meal responses of GLP-1 and PYY3-36
Iepsen, E. W., Lundgren, J., Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, Jun 2016, In: European Journal of Endocrinology. 174, 6, p. 775-784 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Successful Use of a GLP-1 Receptor Agonist as Add-on Therapy to Sulfonylurea in the Treatment of KCNJ11 Neonatal Diabetes
Hindsø, M., Christoffer Martinussen, Maria Saur Svane, Simon Veedfald, Birthe Gade-rasmussen, Torben Hansen & Madsbad, Sten, 2021, In: European Journal of Case Reports in Internal Medicine. 8, 3, 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Succesfuld behandling af KCNJ11-neonatal diabetes uden insulin
Gade-Rasmussen, B., Madsbad, Sten, Svane, M. S., Martinussen, C. & Hansen, Torben, 2018, In: Ugeskrift for Laeger. 180, 46, 2 p., V08180547.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Subcutaneous GIP and GLP-2 inhibit nightly bone resorption in postmenopausal women: A preliminary study
Skov-Jeppesen, Kirsa, Veedfald, Simon, Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2021, In: Bone. 152, 7 p., 116065.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Study rationale and design of the CIMT trial: the Copenhagen Insulin and Metformin Therapy trial
Lundby Christensen, L., Almdal, T., Boesgaard, T., Breum, L., Dunn, E., Gade-Rasmussen, B., Gluud, C., Hedetoft, C., Jarloev, A., Jensen, T., Krarup, T., Johansen, L. B., Lund, S. S., Madsbad, S., Mathiesen, E., Moelvig, J., Nielsen, F., Perrild, H., Pedersen, O., Roeder, M. & 31 others, , 2009, In: Diabetes, Obesity and Metabolism. 11, 4, p. 315-22 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of the Gly482Ser polymorphism of the peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha) gene in Danish subjects with the metabolic syndrome
Ambye, L., Rasmussen, S., Fenger, M., Jørgensen, T., Borch-Johnsen, K., Madsbad, Sten & Urhammer, S., 2005, In: Diabetes Research and Clinical Practice. 67, 2, p. 175-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of the Association of Arg72Pro of Tumor Suppressor Protein p53 with Type 2 Diabetes in a Combined Analysis of 55,521 Europeans
Burgdorf, K. S., Grarup, Niels, Justesen, Johanne Marie, Harder, M. N., Witte, D. R., Jørgensen, T., Sandbæk, A., Lauritzen, T., Madsbad, Sten, Hansen, Torben, DIAGRAM Consortium, D. C. & Pedersen, Oluf Borbye, 2011, In: P L o S One. 6, 1, p. e15813 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7,088 Danish whites
Sparsø, T., Hussain, M. S., Borch-Johnsen, K., Jørgensen, T., Madsbad, Sten, Hansen, Torben, Pedersen, Oluf Borbye & Andersen, G., 2007, In: Molecular Genetics and Metabolism. 92, 3, p. 278-282 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of association between LPIN1 variants and common metabolic phenotypes among 17,538 Danes
Burgdorf, K. S., Sandholt, C. H., Sparsø, T., Andersen, G., Witte, D. R., Jørgensen, T., Sandbaek, A., Lauritzen, T., Sørensen, Thorkild I.A., Madsbad, Sten, Hansen, Torben & Pedersen, Oluf Borbye, 1 Jul 2010, In: European Journal of Endocrinology. 163, 1, p. 81-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Steroid-induced insulin resistance and impaired glucose tolerance are both associated with a progressive decline of incretin effect in first-degree relatives of patients with type 2 diabetes
Jensen, D. H., Aaboe, K., Henriksen, J. E., Vølund, A., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2012, In: Diabetologia. 55, 5, p. 1406-16 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sperm count is increased by diet-induced weight loss and maintained by exercise or GLP-1 analogue treatment: a randomized controlled trial
Andersen, E., Juhl, C. R., Kjøller, E. T., Lundgren, J. R., Janus, C., Dehestani, Y., Saupstad, M., Ingerslev, L. R., Duun, O. M., Jensen, Simon Birk Kjær, Holst, Jens Juul, Stallknecht, Bente Merete, Madsbad, Sten, Torekov, Signe Sørensen & Barrès, Romain, May 2022, In: Human Reproduction. 37, 7, p. 1414–1422 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Soluble urokinase plasminogen activator receptor, C-reactive protein and triglyceride are associated with heart rate variability in non-diabetic Danes
Intzilakis, T., Hartmann, G., Mouridsen, M. R., Eugen-Olsen, J., Kumarathurai, P., Madsbad, Sten, Almdal, Thomas Peter, Haugaard, Steen Bendix & Sajadieh, A., 2013, In: European Journal of Clinical Investigation. 43, 5, p. 457-468 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Skeletal muscle structural lipids improve during weight-maintenance after a very low calorie dietary intervention
Haugaard, Steen Bendix, Vaag, Allan, Mu, Huiling & Madsbad, Sten, 2009, In: Lipids in Health and Disease. 8, p. 34 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Skeletal muscle insulin signaling defects downstream of phosphatidylinositol 3-kinase at the level of akt are associated with impaired nonoxidative glucose disposal in HIV lipodystrophy
Haugaard, S. B., Andersen, O., Madsbad, Sten, Frøsig, C., Iversen, J., Nielsen, J. O. & Wojtaszewski, Jørgen F P, 2005, In: Diabetes. 54, 12, p. 3474-83 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Skeletal muscle insulin signaling defects downstream of PI3K at the level of Akt are associated with impaired non-oxidative glucose disposal in HIV-lipodystrophy
Haugaard, S. B., Andersen, Ove, Madsbad, Sten, Frøsig, C., Iversen, J., Nielsen, J. O. & Wojtaszewski, J. F., 2005, In: Diabetes. 12, 54, p. 3474-83Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Skeletal Muscle Mitochondrial Function in Polycystic Ovarian Syndrome
Rabøl, R., Svendsen, P. M., Skovbro, M., Boushel, R. C., Schjerling, Peter, Nilas, L., Madsbad, Sten & Dela, Flemming, 2011, In: European Journal of Endocrinology. 165, 4, p. 631-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short-term effects of a low carbohydrate diet on glycaemic variables and cardiovascular risk markers in patients with type 1 diabetes: A randomized open-label crossover trial
Ranjan, A., Schmidt, S., Damm-Frydenberg, C., Holst, Jens Juul, Madsbad, Sten & Nørgaard, Kirsten, Oct 2017, In: Diabetes, Obesity and Metabolism. 19, 10, p. 1479-1484Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sex and muscle structural lipids in obese subjects - an impact on insulin action?
Haugaard, S. B., Vaag, Allan, Høy, C. & Madsbad, Sten, 2008, In: European Journal of Clinical Investigation. 38, 7, p. 494-501 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Separate effects of glucagon like peptide-2 (GLP-2) and glucose-dependent insulinotropic polypeptide (GIP) on bone remodelling
Skov-Jeppesen, Kirsa, Svane, M., Martinussen, C., Gabe, M., Gasbjerg, Lærke Smidt, Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2018, In: Diabetologia. 61, S1, p. S245-S245 501.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Semaglutide seems to be more effective the other GLP-1Ras
Holst, Jens Juul & Madsbad, Sten, Dec 2017, In: Annals of Translational Medicine. 5, 24, 5 p., 505.Research output: Contribution to journal › Comment/debate › Research
- Published
Secretin release after Roux-en-Y gastric bypass reveals a population of glucose-sensitive S cells in distal small intestine
Modvig, Ida Marie, Andersen, Daniel Bjørklund, Grunddal, Kaare Villum, Kuhre, Rune Ehrenreich, Martinussen, C., Christiansen, Charlotte Bayer, Ørskov, Cathrine, Larraufie, P., Kay, R. G., Reimann, F., Gribble, F. M., Hartmann, Bolette, Bojsen-Moller, K. N., Madsbad, Sten, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2020, In: International Journal of Obesity. 44, 9, p. 1859-1871Research output: Contribution to journal › Journal article › Research › peer-review
- Published
S100A8/A9 (Calprotectin), Interleukin-6, and C-Reactive Protein in Obesity and Diabetes before and after Roux-en-Y Gastric Bypass Surgery
Lylloff, L., Bathum, L., Madsbad, Sten, Grundtvig, J. L. G., Nordgaard-Lassen, I. & Fenger, M., 2017, In: Obesity Facts. 10, 4, p. 386-395 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Roux-en-Y gastric bypass surgery of morbidly obese patients induces swift and persistent changes of the individual gut microbiota
Palleja, A., Kashani, A., Allin, K. H., Nielsen, T., Zhang, C., Li, Y., Brach, Thorsten, Liang, S., Feng, Q., Jørgensen, N. B., Bojsen-Møller, K. N., Dirksen, C., Burgdorf, Kristoffer Sølvsten, Holst, Jens Juul, Madsbad, Sten, Wang, J., Pedersen, Oluf Borbye, Hansen, Torben & Arumugam, Mani, 2016, In: Genome Medicine. 8, 13 p., 67.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Roux-en-Y gastric bypass surgery does not preserve energy expenditure in humans
Schmidt, J. B., Gunvald, L. E., Gregersen, N. T., Pedersen, S. D., Holst, Jens Juul, Hansen, D. L., Worm, Dorte, Madsbad, Sten, Astrup, A. & Sjödin, Anders Mikael, 2012, In: Regulatory Peptides. 177, suppl.1, p. S32 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Review of head-to-head comparisons of glucagon-like peptide-1 receptor agonists
Madsbad, Sten, Apr 2016, In: Diabetes, Obesity and Metabolism. 18, 4, p. 317-32 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Retinal function in relation to improved glycaemic control in type 1 diabetes
Holfort, S. K., Nørgaard, Kirsten, Jackson, G., Hommel, E., Madsbad, Sten, Munch, I. C., Klemp, K., Sander, B. & Larsen, Michael, 2011, In: Diabetologia. 54, 7, p. 1853-61 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Retinal characteristics during 1 year of insulin pump therapy in type 1 diabetes: a prospective, controlled, observational study
Klefter, O. N., Hommel, E., Munch, I. C., Nørgaard, Kirsten, Madsbad, Sten & Larsen, Michael, Sep 2016, In: Acta Ophthalmologica. 94, 6, p. 540-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Restoration of the insulinotropic effect of glucose-dependent insulinotropic polypeptide contributes to the antidiabetic effect of dipeptidyl peptidase-4 inhibitors
Aaboe, K., Akram, S., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., Jan 2015, In: Diabetes, Obesity and Metabolism. 17, 1, p. 74-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Instrumentalization of eating improves weight loss maintenance in obesity
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Treatment with liraglutide may improve markers of CVD reflected by reduced levels of apoB
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Roux-en-Y gastric bypass surgery of morbidly obese patients induces swift and persistent changes of the individual gut microbiota
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