Ulrik Gether

Ulrik Gether

Head of Department, Professor

ORCID: 0000-0002-0020-3807

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  1. Published

    [Leu31, Pro34]neuropeptide Y: a specific Y1 receptor agonist

    Fuhlendorff, J., Gether, Ulrik, Aakerlund, L., Langeland-Johansen, N., Thøgersen, H., Melberg, S. G., Olsen, U. B., Thastrup, Ole & Schwartz, Thue W., 1990, In: Proceedings of the National Academy of Sciences of the United States of America. 87, 1, p. 182-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Zn2+ modulation of neurotransmitter transporters

    Nørgaard-Nielsen, K. & Gether, Ulrik, 2006, In: Handbook of Experimental Pharmacology. 175, p. 1-22 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Zn(2+) site engineering oat the oligomeric interface of the dopamine transporter

    Nørgaard-Nielsen, K., Norregaard, L., Hastrup-Nielsen, H., Javitch, J. A. & Gether, Ulrik, 2002, In: FEBS Letters. vol. 524(1-3), p. 87-91

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Zn(2+) site engineering at the oligomeric interface of the dopamine transporter

    Norgaard-Nielsen, K., Norregaard, L., Hastrup, H., Javitch, J. A. & Gether, Ulrik, 31 Jul 2002, In: FEBS Letters. 524, 1-3, p. 87-91 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Zinc Potentiates an Uncoupled Anion Conductance Associated with the Dopamine Transporter

    Meinild, A., Sitte, H. H. & Gether, Ulrik, 2004, In: Journal of Biological Chemistry. 279, 48, p. 49671-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Y1 receptors for neuropeptide Y are coupled to mobilization of intracellular calcium and inhibition of adenylate cyclase

    Aakerlund, L., Gether, Ulrik, Fuhlendorff, J., Schwartz, Thue W. & Thastrup, Ole, 1990, In: F E B S Letters. 260, 1, p. 73-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release

    Gotfryd, K., Boesen, T., Mortensen, Jonas Sigurd, Khelashvili, G., Quick, M., Terry, D. S., Missel, Julie Winkel, LeVine, M. V., Gourdon, Pontus Emanuel, Blanchard, S. C., Javitch, J. A., Weinstein, H., Loland, Claus Juul, Nissen, P. & Gether, Ulrik, 2020, In: Nature Communications. 11, 1, 14 p., 1005.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Within-Mice Comparison of Microdialysis and Fiber Photometry-Recorded Dopamine Biosensor during Amphetamine Response

    Ejdrup, Aske Lykke, Wellbourne-Wood, J., Dreyer, J. K., Guldhammer, N., Lycas, M. D., Gether, Ulrik, Hall, B. J. & Sørensen, G., 2023, In: ACS Chemical Neuroscience. 14, 9, 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Water transport by the human Na+-coupled glutamate cotransporter expressed in Xenopus oocytes

    MacAulay, Nanna, Gether, Ulrik, Klaerke, D. A. & Zeuthen, T., 2001, In: Journal of Physiology. 530 (Pt 3), p. 367-378

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Visualization of dopamine transporter trafficking in live neurons by use of fluorescent cocaine analogs

    Eriksen, J., Rasmussen, Søren Gøgsig Faarup, Jørgensen, T. N., Vaegter, C. B., Cha, J. H., Zou, M., Newman, A. H. & Gether, Ulrik, 2009, In: Journal of Neuroscience. 29, 21, p. 6794-808 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Validity of the diagnosis of a single depressive episode in a case register

    Bock, C., Bukh, Jens Otto Drachmann, Vinberg, Maj, Gether, Ulrik, Kessing, Lars Vedel, Bock, C., Bukh, J. D., Vinberg, Maj, Gether, U. & Kessing, Lars Vedel, 2009, In: Clinical Practice and Epidemiology in Mental Health. 5, p. 4

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Use of fluorescence spectroscopy to study conformational changes in the beta 2-adrenoceptor

    Kobilka, B. K. & Gether, Ulrik, 2002, In: Methods in Enzymology. 343, 343, p. 170-182 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Understanding G-protein coupled receptors and their role in the CNS

    Rasmussen, Søren Gøgsig Faarup & Gether, Ulrik, 2002, Structural mechanics of GPCR activation. p. 43-62

    Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research

  14. Published

    Uncovering molecular mechanism involved in activation of G protein-coupled receptors

    Gether, Ulrik, 2000, In: Endocrine Reviews. 21(1), p. 90-113

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Transmembrane transporter proteins: Capturing transport in motion

    Loland, Claus Juul, Wellendorph, Petrine, Pedersen, Stine Helene Falsig & Gether, Ulrik, 2024, In: Basic and Clinical Pharmacology and Toxicology. 134, 2, p. 203-205 3 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  16. Published

    Transition metal ion FRET uncovers K(+) regulation of a neurotransmitter/sodium symporter

    Billesbølle, C. B., Mortensen, Jonas Sigurd, Sohail, A., Schmidt, S. G., Shi, L., Sitte, H. H., Gether, Ulrik & Loland, Claus Juul, 28 Sep 2016, In: Nature Communications. 7, 12 p., 12755.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Theory of visual attention (TVA) applied to rats performing the 5-choice serial reaction time task: differential effects of dopaminergic and noradrenergic manipulations

    Hervig, M. E. S., Toschi, C., Petersen, Anders, Vangkilde, Signe, Gether, Ulrik & Robbins, T. W., 2023, In: Psychopharmacology. 240, p. 41-58 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Theory of Visual Attention (TVA) applied to mice in the 5-choice serial reaction time task

    Fitzpatrick, C. M., Caballero-Puntiverio, M., Gether, Ulrik, Habekost, Thomas, Bundesen, C., Vangkilde, Signe, Woldbye, David Paul Drucker, Andreasen T., Jesper & Petersen, Anders, 2017, In: Psychopharmacology. 234, 5, p. 845-855

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    The solute carrier 6 family of transporters

    Bröer, S. & Gether, Ulrik, 22 Aug 2012, In: British Journal of Pharmacology. 167, 2, p. 256-78 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    The serotonin transporter undergoes constitutive internalization and is primarily sorted to late endosomes and lysosomal degradation

    Rahbek-Clemmensen, T., Bay, T., Eriksen, J., Gether, Ulrik & Jørgensen, T. N., 27 Jun 2014, In: The Journal of Biological Chemistry. 289, p. 23004-23019 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The second sodium site in the dopamine transporter controls cation permeability and is regulated by chloride

    Borre, L., Andreassen, T. F., Shi, L., Weinstein, H. & Gether, Ulrik, 25 Jul 2014, In: The Journal of Biological Chemistry. 289, p. 25764-25773 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The role of zine ions in reverse transport mediated by monoamine transporters

    Scholze, P., Norregaard, L., Singer, E. A., Freissmuth, M., Gether, Ulrik & Sitte, H. H., 2002, In: Journal of Biological Chemistry. 277, p. 21505-21513

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    The role of zinc ions in reverse transport mediated by monoamine transporters

    Scholze, P., Nørregaard, L., Singer, E. A., Freissmuth, M., Gether, Ulrik & Sitte, H. H., 14 Jun 2002, In: Journal of Biological Chemistry. 277, 24, p. 21505-13 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    The mechanism of a high-affinity allosteric inhibitor of the serotonin transporter

    Plenge, P., Abramyan, A. M., Sørensen, G., Mork, A., Weikop, Pia, Gether, Ulrik, Bang-Andersen, B., Shi, L. & Loland, Claus Juul, 2020, In: Nature Communications. 11, 1, 12 p., 1491.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The influence of comorbid personality disorder and neuroticism on treatment outcome in first episode depression

    Bock, C., Bukh, Jens Otto Drachmann, Vinberg, Maj, Gether, Ulrik, Kessing, Lars Vedel, Bock, C., Bukh, J. O. D., Vinberg, Maj, Kessing, Lars Vedel & Gether, U., 1 Jan 2010, In: Psychopathology. 43, 3, p. 197-204 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    The effect of pH on ß2 adrenoceptor function

    Pejman, G., Hans, S., Roland, S., Tae Weon, L., Rasmussen, Søren Gøgsig Faarup, Gether, Ulrik & Kobilka, B. K., 2000, In: Journal of Biological Chemistry. 5, Vol. 275, p. 3121-3127

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    The effect of escitalopram versus placebo on perceived stress and salivary cortisol in healthy first-degree relatives of patients with depression-A randomised trial

    Knorr, Ulla Benedichte Søsted, Vinberg, Maj, Gether, Ulrik, Winkel, P., Gluud, C., Wetterslev, J. & Kessing, Lars Vedel, 30 Dec 2012, In: Psychiatry Research Review. 200, 2-3, p. 354-60 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    The binding sites for cocaine and dopamine in the dopamine transporter overlap.

    Beuming, T., Kniazeff, J., Bergmann, M. L., Shi, L., Gracia, L., Raniszewska, K., Newman, A. H., Javitch, J. A., Weinstein, H., Gether, Ulrik & Loland, Claus Juul, 2008, In: Nature Neuroscience. 11, 7, p. 780-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    The binding sites for benztropines and dopamine in the dopamine transporter overlap

    Jensen, H. B., Larsen, M. A. B., Mazier, S., Beuming, T., Weinstein, H., Shi, L., Loland, Claus Juul & Gether, Ulrik, 1 Jan 2011, In: Neuropharmacology. 60, 1, p. 182-90 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    The Scaffold Protein PICK1 as a Target in Chronic Pain

    Sørensen, Andreas Toft, Rombach, Joscha, Gether, Ulrik & Madsen, Kenneth Lindegaard, 2022, In: Cells. 11, 8, 1255.

    Research output: Contribution to journal › Review › Research › peer-review

  31. Published

    The N terminus of monoamine transporters is a lever required for the action of amphetamines

    Sucic, S., Dallinger, S., Zdrazil, B., Weissensteiner, R., Jørgensen, T. N., Holy, M., Kudlacek, O., Seidel, S., Cha, J. H., Gether, Ulrik, Newman, A. H., Ecker, G. F., Freissmuth, M. & Sitte, H. H., 2010, In: Journal of Biological Chemistry. 285, 14, p. 10924-38 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    The GPRC6A Receptor displays Constitutive Internalization and Sorting to the Slow Recycling Pathway

    Jacobsen, S. E., Ammendrup-Johnsen, I., Jansen, A. M., Gether, Ulrik, Madsen, Kenneth Lindegaard & Bräuner, Hans, 2017, In: The Journal of Biological Chemistry. 292, 17, p. 6910-6926

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    The Environment Shapes the Inner Vestibule of LeuT

    Sohail, A., Jayaraman, K., Venkatesan, S., Gotfryd, K., Daerr, M., Gether, Ulrik, Loland, Claus Juul, Wanner, K. T., Freissmuth, M., Sitte, H. H., Sandtner, W. & Stockner, T., Nov 2016, In: PLoS Computational Biology. 12, 11, 24 p., e1005197.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    The BAR Domain Protein PICK1 Controls Vesicle Number and Size in Adrenal Chromaffin Cells

    da Silva Pinheiro, P. C., Jansen, A. M., de Wit, H., Tawfik, B., Madsen, Kenneth Lindegaard, Verhage, M., Gether, Ulrik & Sørensen, Jakob Balslev, 6 Aug 2014, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 34, 32, p. 10688-700 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Tandem Facial Amphiphiles for Membrane Protein Stabilization

    Chae, P. S., Gotfryd, K., Pacyna, J., Miercke, L. J. W., Rasmussen, Søren Gøgsig Faarup, Robbins, R. A., Rana, R. R., Loland, Claus Juul, Kobilka, B., Stroud, R., Byrne, B., Gether, Ulrik & Gellman, S. H., 1 Dec 2010, In: Journal of the American Chemical Society. 132, 47, p. 16750-2 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Syntaxin 1A interaction with the dopamine transporter promotes amphetamine-induced dopamine efflux

    Binda, F., Dipace, C., Bowton, E., Robertson, S. D., Lute, B. J., Fog, J. U., Zhang, M., Sen, N., Colbran, R. J., Gnegy, M. E., Gether, Ulrik, Javitch, J. A., Erreger, K. & Galli, A., 2008, In: Molecular Pharmacology. 74, 4, p. 1101-1108 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Surface targeting of the dopamine transporter involves discrete epitopes in the distal C terminus but does not require canonical PDZ domain interactions

    Bjerggaard, C., Fog, J. U., Hastrup, H., Madsen, Kenneth Lindegaard, Loland, C. J., Javitch, J. A. & Gether, Ulrik, 2004, In: Journal of Neuroscience. 24, 31, p. 7024-36 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Surface targeting of the dopamine transporter involves discrete epitopes in the distal C terminus but does not require canonical PDZ doamin interactions

    Bjerggaard, C., Fog, J. U., Hastrup-Nielsen, H., Madsen, K., Loland, Claus Juul, Javitch, J. & Gether, Ulrik, 2004, In: Journal of Neuroscience. Vol. 24, no. 31, p. 7024-36

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Super-resolution microscopy reveals functional organization of dopamine transporters into cholesterol and neuronal activity-dependent nanodomains

    Rahbek-Clemmensen, T., Lycas, M. D., qrc243, qrc243, Eriksen, J., Apuschkin, Mia, Vilhardt, Frederik, Jorgensen, T. N., Herborg, Freja & Gether, Ulrik, 2017, In: Nature Communications. 8, 14 p., 740.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Substrate-modulated unwinding of transmembrane helices in the NSS transporter LeuT: Recommended in F1000Prime as being of special significance in its field by F1000 Faculty Member Robert Vandenberg

    Merkle, P. S., Gotfryd, K., Cuendet, M. A., Leth-Espensen, K. Z., Gether, Ulrik, Loland, Claus Juul & Rand, Kasper Dyrberg, 2018, In: Science Advances. 4, 5, 12 p., eaar6179.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Substrate-induced Unlocking of the Inner Gate Determines the Catalytic Efficiency of a Neurotransmitter: Sodium Symporter

    Billesbolle, C. B., Kruger, M. B., Shi, L., Quick, M., Li, Z., Stolzenberg, S., Kniazeff, J., Gotfryd, K., Mortensen, Jonas Sigurd, Javitch, J. A., Weinstein, H., Loland, Claus Juul & Gether, Ulrik, 30 Oct 2015, In: Journal of Biological Chemistry. 290, 44, p. 26725-26738 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Subjective perception of cocaine reward in mice assessed by a single exposure place preference (sePP) paradigm

    Runegaard, A. H., Jensen, Kathrine Louise, Dencker, D., Wörtwein, Gitta & Gether, Ulrik, 2017, In: Journal of Neuroscience Methods. 289, p. 85-92 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Structure-activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1

    Bach, Anders, Stuhr-Hansen, N., Thorsen, T. S., Bork, N., Moreira, I. S., Frydenvang, Karla Andrea, Padrah, S., Christensen, Søren Brøgger, Madsen, Kenneth Lindegaard, Weinstein, H., Gether, Ulrik & Strømgaard, Kristian, 2010, In: Organic & Biomolecular Chemistry. 8, 19, p. 4281-4288 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Structure-activity relationship studies of citalopram derivatives: examining substituents conferring selectivity for the allosteric site in the serotonin transporter

    Larsen, M. A. B., Plenge, P., Andersen, J., Eildal, J. N. N., Kristensen, Anders Skov, Bøgesø, K. P., Gether, Ulrik, Strømgaard, Kristian, Bang-Andersen, B. & Loland, Claus Juul, Mar 2016, In: British Journal of Pharmacology. 173, 5, p. 925-936 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Structure of dimeric and tetrameric complexes of the BAR domain protein PICK1 determined by small-angle X-Ray scattering

    Karlsen, M. L., Thorsen, T. S., Johner, N., Ammendrup-Johnsen, I., qrc243, qrc243, Tian, X., Simonsen, J. B., Hoiberg-Nielsen, R., Christensen, N. M., Khelashvili, G., Streicher, W., Teilum, Kaare, Vestergaard, Bente, Weinstein, H., Gether, Ulrik, Arleth, Lise & Madsen, Kenneth Lindegaard, 7 Jul 2015, In: Structure. 23, 7, p. 1258-1270 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Structural probing of a microdomain in the dopamine transporter by engineering of artificial Zn2+ binding sites

    Norregaard, L., Visiers, I., Loland, Claus Juul, Ballesteros, J., Weinstein, H. & Gether, Ulrik, 26 Dec 2000, In: Biochemistry. 39, 51, p. 15836-15846 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Structural probing of a microdomain in the dopamine transporter by engineering of artificial Zn2+ binding sites

    Norregaard, L., Visiers, I., Loland, Claus Juul, Ballesteros, J. A., Weinstein, H. & Gether, Ulrik, 2001, In: Biochemistry. 39 (51), p. 15836-15846

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Structural biology: Antidepressants at work

    Caron, M. G. & Gether, Ulrik, 21 Apr 2016, In: Nature. 532, p. 320-321 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  49. Published

    Structural basis of organic cation transporter-3 inhibition

    Khanppnavar, B., Maier, J., Herborg, Freja, Gradisch, R., Lazzarin, E., Luethi, D., Yang, J. W., Qi, C., Holy, M., Jäntsch, K., Kudlacek, O., Schicker, K., Werge, Thomas, Gether, Ulrik, Stockner, T., Korkhov, V. M. & Sitte, H. H., 2022, In: Nature Communications. 13, 1, 13 p., 6714.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Structural basis for activation of G-protein-coupled receptors.

    Gether, Ulrik, Asmar, F., Meinild, A. K. & Rasmussen, Søren Gøgsig Faarup, 2002, In: Basic & Clinical Pharmacology & Toxicology. 91, 6, p. 304-12 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Structural and functional probing of the biogenic amine transporters by fluorescence spectroscopy

    Rasmussen, Søren Gøgsig Faarup, Adkins, E. M., Carroll, F. I., Maresch, M. J. & Gether, Ulrik, 31 Oct 2003, In: European Journal of Pharmacology. 479, 1-3, p. 13-22 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Steric hindrance mutagenesis in the conserved extracellular vestibule impedes allosteric binding of antidepressants to the serotonin transporter

    Plenge, P., Shi, L., Beuming, T., Te, J., Newman, A. H., Weinstein, H., Gether, Ulrik & Loland, Claus Juul, 16 Nov 2012, In: The Journal of Biological Chemistry. 287, 47, p. 39316-26 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Serotonin-induced down-regulation of cell surface serotonin transporter

    Jørgensen, T. N., Christensen, P. M. & Gether, Ulrik, Jul 2014, In: Neurochemistry International. 73, p. 107-12 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Serine 77 in the PDZ domain of PICK1 is a protein kinase Cα phosphorylation site regulated by lipid membrane binding

    Ammendrup-Johnsen, I., Thorsen, T. S., Gether, Ulrik & Madsen, Kenneth Lindegaard, 17 Jan 2012, In: Biochemistry. 51, 2, p. 586-96 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation

    Kristensen, Anders Skov, Andersen, J., Jørgensen, T. N., Sørensen, L., Eriksen, J., Loland, Claus Juul, Strømgaard, Kristian & Gether, Ulrik, 1 Sep 2011, In: Pharmacological Reviews. 63, 3, p. 585-640 56 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. E-pub ahead of print

    Role of dopamine neurons in familiarity

    Fleury, S., Kolaric, R., Espera, J., Ha, Q., Tomaio, J., Gether, Ulrik, Sørensen, Andreas Toft & Mingote, S., 2024, (E-pub ahead of print) In: European Journal of Neuroscience.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Rhodamine-labeled 2beta-carbomethoxy-3beta-(3,4-dichlorophenyl)tropane analogues as high-affinity fluorescent probes for the dopamine transporter

    Cha, J. H., Zou, M., Adkins, E. M., Rasmussen, Søren Gøgsig Faarup, Loland, Claus Juul, Schoenenberger, B., Gether, Ulrik & Newman, A. H., 1 Dec 2005, In: Journal of Medicinal Chemistry. 48, 24, p. 7513-6 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Residues in the extracellular loop 4 are critical for maintaining the conformational equilibrium of the gamma-aminobutyric acid transporter-1.

    MacAulay, Nanna, Meinild, A., Zeuthen, Thomas & Gether, Ulrik, 2003, In: Journal of Biological Chemistry. 278, 31, p. 28771-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Reply to Wilkinson et al. Concerning the use of pHluorin-tagged GluA2 as a reporter for NMDA-induced AMPA receptor recycling

    Rathje, Mette, Fang, H., Bachman, J. L., Gether, Ulrik, Huganir, R. L. & Madsen, Kenneth Lindegaard, 21 Jan 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 3, p. E305 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Reliability of clinical ICD-10 diagnoses among electroconvulsive therapy patients with chronic affective disorders

    Jakobsen, K. D., Hansen, T. F., Dam, H., Larsen, E. B., Gether, Ulrik & Werge, Thomas, 2008, In: European Journal of Psychiatry. 22, 3, p. 161-172 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Relationship between conformational changes in the dopamine transporter and cocaine-like subjective effects of uptake inhibitors.

    Loland, Claus Juul, Desai, R. I., Zou, M., Cao, J., Grundt, P., Gerstbrein, K., Sitte, H. H., Newman, A. H., Katz, J. L. & Gether, Ulrik, 2007, In: Molecular Pharmacology. 73, 3, p. 813-23 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Regulation of dopamine transporter trafficking by intracellular amphetamine.

    Kahlig, K. M., Lute, B. J., Wei, Y., Loland, Claus Juul, Gether, Ulrik, Javitch, J. A. & Galli, A., 2006, In: Molecular Pharmacology. 70, 2, p. 542-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Regulation of dopamine transporter function by protein-protein interactions: new discoveries and methodological challenges

    Eriksen, J., Jørgensen, T. N. & Gether, Ulrik, 2010, In: Journal of Neurochemistry. 113, 1, p. 27-41 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Recruitment of beta-arrestin2 to the dopamine D2 receptor: insights into anti-psychotic and anti-parkinsonian drug receptor signaling

    Klewe, I. V., Nielsen, S. M., Tarpø, L., Urizar, E., Dipace, C., Javitch, J. A., Gether, Ulrik, Egebjerg, J. & Christensen, K. V., 2008, In: Neuropharmacology. 54, 8, p. 1215-1222 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Rationale and design of the participant, investigator, observer, and data-analyst-blinded randomized AGENDA trial on associations between gene-polymorphisms, endophenotypes for depression and antidepressive intervention: the effect of escitalopram versus placebo on the combined dexamethasone-corticotrophine releasing hormone test and other potential endophenotypes in healthy first-degree relatives of persons with depression

    Knorr, Ulla Benedichte Søsted, Vinberg, Maj, Klose, M., Feldt-Rasmussen, Ulla, Hilsted, Linda, Gade, A., Haastrup, E., Paulson, Olaf B., Wetterslev, J., Gluud, C., Gether, Ulrik & Kessing, Lars Vedel, 2009, In: Trials. 10, p. 66

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Rare autism-associated variants implicate syntaxin 1 (STX1 R26Q) phosphorylation and the dopamine transporter (hDAT R51W) in dopamine neurotransmission and behaviors

    Cartier, E., Hamilton, P. J., Belovich, A. N., Shekar, A., Campbell, N. G., Saunders, C., Andreassen, T. F., Gether, Ulrik, Veenstra-Vanderweele, J., Sutcliffe, J. S., Ulery-Reynolds, P. G., Erreger, K., Matthies, H. J. G. & Galli, A., Feb 2015, In: EBioMedicine. 2, 2, p. 135-146 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Rab2 drives axonal transport of dense core vesicles and lysosomal organelles

    Lund, Viktor Karlovich, Lycas, M. D., Schack, A., Andersen, Rita Chan, Gether, Ulrik & Kjærulff, Ole, 2021, In: Cell Reports. 35, 2, 26 p., 108973.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Purification and fluorescent labeling of the human serotonin transporter

    Rasmussen, Søren Gøgsig Faarup & Gether, Ulrik, 8 Mar 2005, In: Biochemistry. 44, 9, p. 3494-505 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Protein interacting with C-kinase 1 (PICK1) binding promiscuity relies on unconventional PSD-95/Discs-Large/ZO-1 homology (PDZ) binding modes for nonclass II PDZ ligands

    qrc243, qrc243, Rathje, Mette, Heiðarsson, P. O., Poulsen, F. M., Madsen, Kenneth Lindegaard, Teilum, Kaare & Gether, Ulrik, 2014, In: Journal of Biological Chemistry. 289, 36, p. 25327-25340 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Protein interacting with C kinase 1 (PICK1) reduces reinsertion rates of interaction partners sorted to Rab11-dependent slow recycling pathway

    Madsen, Kenneth Lindegaard, Thorsen, T. S., Rahbek-Clemmensen, T., Eriksen, J. M. & Gether, Ulrik, 6 Apr 2012, In: The Journal of Biological Chemistry. 287, 15, p. 12293-308 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Probing dopamine transporter structure and function y Zn2+ site engineering

    Loland, Claus Juul, Nørgaard-Nielsen, K. & Gether, Ulrik, 2003, In: European Journal of Pharmacology. Vol. 479, no 1-3, p. 187-97

    Research output: Contribution to journal › Review › Research › peer-review

  72. Published

    Probing dopamine transporter structure and function by Zn2+-site engineering

    Loland, Claus Juul, Norgaard-Nielsen, K. & Gether, Ulrik, 31 Oct 2003, In: European Journal of Pharmacology. 479, 1-3, p. 187-97 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Preserved dopaminergic homeostasis and dopamine-related behaviour in hemizygous TH-Cre mice

    Thomsen, A. H. R., Jensen, Kathrine Louise, Fitzpatrick, C. M., Dencker, D., Weikop, Pia, Gether, Ulrik & Rickhag, Karl Mattias, Jan 2017, In: European Journal of Neuroscience. 45, 1, p. 121-128

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Postendocytic sorting of constitutively internalized dopamine transporter in cell lines and dopaminergic neurons

    Eriksen, J., Bjørn-Yoshimoto, Walden, Jørgensen, T. N., Newman, A. H. & Gether, Ulrik, 2010, In: Journal of Biological Chemistry. 285, 35, p. 27289-301 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Phosphorylation of the norepinephrine transporter at threonine 258 and serine 259 is linked to protein kinase C-mediated transporter internalization

    Jayanthi, L. D., Annamalai, B., Samuvel, D. J., Gether, Ulrik & Ramamoorthy, S., 2006, In: Journal of Biological Chemistry. 281, 33, p. 23326-40 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Passive water and urea permeability of a human Na(+)-glutamate cotransporter expressed in Xenopus oocytes

    MacAulay, Nanna, Gether, Ulrik, Klærke, Dan Arne & Zeuthen, Thomas, 2002, In: Journal of Physiology. 542, 3, p. 817-828 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Partial Unwinding of Transmembrane Helices Facilitates Alternating Access in the Neurotransmitter: Sodium Symporter LeuT

    Merkle, P. S., Gotfryd, K., Cuendet, M. A., Leth-Espensen, K. Z., Gether, Ulrik, Loland, Claus Juul & Rand, Kasper Dyrberg, 28 Jun 2017

    Research output: Other contribution › Research

  78. Published

    PICK1-Deficient Mice Exhibit Impaired Response to Cocaine and Dysregulated Dopamine Homeostasis

    Jensen, Kathrine Louise, Sørensen, G., Dencker, D., Owens, W. A., Rahbek-Clemmensen, T., Brett Lever, M., Runegaard, A. H., Riis Christensen, N., Weikop, Pia, Wörtwein, Gitta, Fink-Jensen, Anders, Madsen, Kenneth Lindegaard, Daws, L., Gether, Ulrik & Rickhag, Karl Mattias, 2018, In: eNeuro. 5, 3

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    PICK1 expression in the Drosophila central nervous system primarily occurs in the neuroendocrine system

    Jansen, A. M., Nässel, D. R., Madsen, Kenneth Lindegaard, Jung, A. G., Gether, Ulrik & Kjærulff, Ole, 2009, In: Journal of Comparative Neurology. 517, 3, p. 313-32 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    PICK1 deficiency impairs secretory vesicle biogenesis and leads to growth retardation and decreased glucose tolerance

    Holst, Birgitte, Madsen, Kenneth Lindegaard, Jansen, A. M., Jin, C., Rickhag, Karl Mattias, Lund, Viktor Karlovich, Jensen, M., Bhatia, V., Sørensen, G., Madsen, A. N., Xue, Z., Møller, S. K., Woldbye, David Paul Drucker, Qvortrup, Klaus, Huganir, R., Stamou, Dimitrios, Kjærulff, Ole & Gether, Ulrik, Apr 2013, In: P L o S Biology (Online). 11, 4, p. 1-25 25 p., e1001542.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Optogenetik bringer neurale mekanismer frem i lyset og kan blive en ny terapiform

    Axelsen, T. M., Navntoft, C. A. E., Christiansen, S. H., Dreyer, J. K., Sørensen, Jakob Balslev, Gether, Ulrik & Woldbye, David Paul Drucker, 17 Aug 2015, In: Ugeskrift for Laeger. 177, 34, p. 2-5 4 p., V06150501.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Obituary

    Brøsen, K., Simonsen, U. & Gether, Ulrik, 2018, In: Basic & clinical pharmacology & toxicology. 123, 5, p. 521-522 2 p.

    Research output: Contribution to journal › Comment/debate › Communication

  83. Published

    Novel and high affinity fluorescent ligands for the serotonin transporter based on (s)-citalopram

    Kumar, V., Rahbek-Clemmensen, T., Billesbølle, C. B., Jorgensen, T. N., Gether, Ulrik & Newman, A. H., 12 Jun 2014, In: A C S Medicinal Chemistry Letters. 5, 6, p. 696-9 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Novel Tripod Amphiphiles for Membrane Protein Analysis

    Chae, P. S., Kruse, A. C., Gotfryd, K., Rana, R. R., Cho, K. H., Rasmussen, Søren Gøgsig Faarup, Bae, H. E., Chandra, R., Gether, Ulrik, Guan, L., Kobilka, B. K., Loland, Claus Juul, Byrne, B. & Gellman, S. H., 2 Oct 2013, In: Chemistry: A European Journal. 19, 46

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Novel Fluorescent Ligands Enable Single-Molecule Localization Microscopy of the Dopamine Transporter

    Guthrie, D. A., Klein Herenbrink, Carmen, Lycas, M. D., Ku, T., Bonifazi, A., Devree, B. T., Mathiasen, Signe, Javitch, J. A., Grimm, J. B., Lavis, L., Gether, Ulrik & Newman, A. H., 2020, In: ACS Chemical Neuroscience. 11, 20, p. 3288-3300 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    No interactions between genetic polymorphisms and stressful life events on outcome of antidepressant treatment

    Bukh, Jens Otto Drachmann, Bock, C., Vinberg, Maj, Werge, Thomas, Gether, Ulrik, Kessing, Lars Vedel, Bukh, J. D., Bock, C., Vinberg, Maj, Werge, Thomas, Gether, U. & Kessing, Lars Vedel, 2009, In: European Neuropsychopharmacology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    No effect of escitalopram versus placebo on brain-derived neurotrophic factor in healthy individuals: a randomised trial

    Knorr, Ulla Benedichte Søsted, Koefoed, P., Soendergaard, M. H. G., Vinberg, Maj, Gether, Ulrik, Gluud, C., Wetterslev, J., Winkel, P. & Kessing, Lars Vedel, Apr 2016, In: Acta Neuropsychiatrica. 28, 2, p. 101-109 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Neurotransmitter transporters: structure and function

    Loland, Claus Juul & Gether, Ulrik, 2009, Texbook of Drug Design and Discovery. Madsen, U., Krogsgaard-Larsen, P. & Stromgaard, K. (eds.). 4 ed. Taylor & Francis

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

  89. Published

    Neurotransmitter transporters: molecular function of important drug targets

    Gether, Ulrik, Andersen, P. H., Larsson, O. M. & Schousboe, A., 2006, In: Trends in Pharmacological Sciences. 27, 7, p. 375-383 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Neurotransmitter transporters: molecular function of important drug targets

    Gether, Ulrik, Andersen, P. H., Larsson, O. M. & Schousboe, Arne, Jul 2006, In: Trends in Pharmacological Sciences. 27, 7, p. 375-83 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Neurotransmitter Transporters: Structure, Function, and Drug Binding

    Loland, Claus Juul & Gether, Ulrik, 2017, Textbook of Drug Design and Discovery. Stromgaard, K., Krogsgaard-Larsen, P. & Madsen, U. (eds.). 5 ed. Boca Raton: CRC Press, p. 233-248 16 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

  92. Published

    Neuropsychiatric disease-associated genetic variants of the dopamine transporter display heterogeneous molecular phenotypes

    Herborg, Freja, Andreassen, T. F., Berlin, F., Loland, Claus Juul & Gether, Ulrik, 2018, In: The Journal of Biological Chemistry. 293, 19, p. 7250-7262 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Nanoscopic dopamine transporter distribution and conformation are inversely regulated by excitatory drive and D2 autoreceptor activity

    Lycas, M. D., Ejdrup, Aske Lykke, Sørensen, Andreas Toft, Haahr, N. O., Jørgensen, Søren Heide, Guthrie, D. A., Støier, J. F., Werner, C., Newman, A. H., Sauer, M., Herborg, Freja & Gether, Ulrik, 2022, In: Cell Reports. 40, 13, 27 p., 111431.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter internalization

    Granas, C., Ferrer, J., Loland, Claus Juul, Javitch, J. A. & Gether, Ulrik, 14 Feb 2003, In: The Journal of Biological Chemistry. 278, 7, p. 4990-5000 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter interanalization

    Granas, C., Ferrer, J., Loland, Claus Juul, Javitch, J. A. & Gether, Ulrik, 2003, In: Journal of Biological Chemistry. Vol. 278 (7), p. 4990-5000

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Mutation of a conserved aspartic acid in the Beta2 adrenergic recptor: constitutive activation, structural instability, and conformational rearrangement of transmembrane segment VI

    Rasmussen, Søren Gøgsig Faarup, Dam Jensen, A., Ghanouni, P., Liapakis, G., Javitch, J. & Gether, Ulrik, 1999, In: Molecular Pharmacology. 56, p. 175-184

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Multimodal detection of dopamine by sniffer cells expressing genetically encoded fluorescent sensors

    Klein Herenbrink, Carmen, Støier, J. F., Reith, W. D., Dagra, A., Gregorek, M. A. C., Cola, R. B., Patriarchi, T., Li, Y., Tian, L., Gether, Ulrik & Herborg, Freja, 2022, In: Communications Biology . 5, 1, 578.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Molecular mechanisms of GPCR activation

    Rasmussen, Søren Gøgsig Faarup & Gether, Ulrik, 2006, G Protein-Coupled Receptors as Drug Targets: Analysis of Activation and Constitutive ActivityG Protein-Coupled Receptors as Drug Targets: Analysis of Activation and Constitutive Activity. 2006: Wiley, Vol. 24. p. 27-42 16 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  99. Published

    Molecular mechanism of action of non-peptide ligands for peptide receptors

    Schwartz, Thue W., Gether, Ulrik, Schambye, H. T. & Hjorth, Siv Annegrethe, Oct 1995, In: Current Pharmaceutical Design. 1, 3, p. 325-342 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Molecular determinants for the complex binding specifity of the PDZ domain in PICK1

    Madsen, K. L., Beuming, T., Niv, M. Y., Chang, C. W., Dev, K. K., Weinstein, H. & Gether, Ulrik, 2005, In: Journal of Biological Chemistry. Vol. 280, no. 21, p. 20539-48

    Research output: Contribution to journal › Journal article › Research › peer-review

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