Thor Grundtvig Theander
Professor
Centre for Medical Parasitology
Blegdamsvej 3, 2200 København N, Building: 07-11-17
CMP
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-11-TR4
Member of:
CMP-BIOENGINEERING
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Development of a bispecific immune engager using a recombinant malaria protein
Nordmaj, Mie Anemone, Roberts, M. E., Sachse, E. S., Dagil, Robert, Andersen, Anne Poder, Skeltved, Nanna, Grunddal, Kaare Villum, Erdogan, Sayit Mahmut, Choudhary, Swati, Gustavsson, Tobias, Ørum-madsen, M. S., Moskalev, I., Tian, W., Yang, Zhang, Clausen, Thomas Mandel, Theander, Thor Grundtvig, Daugaard, M., Nielsen, Morten Agertoug & Salanti, Ali, 2021, In: Cell Death & Disease. 12, 4, 11 p., 353.Research output: Contribution to journal › Journal article › Research › peer-review
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Development of a fetal weight chart using serial trans-abdominal ultrasound in an East African population: A longitudinal observational study
Schmiegelow, Christentze, Scheike, Thomas, Oesterholt, M., Minja, D., Pehrson, Caroline, Magistrado, P., Lemnge, M., Rasch, V., Lusingu, J., Theander, Thor Grundtvig & Nielsen, B. B., 2012, In: P L o S One. 7, 9, e44773.Research output: Contribution to journal › Journal article › Research › peer-review
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Diagnosis of visceral leishmaniasis by the polymerase chain reaction using blood, bone marrow and lymph node samples from patients from the Sudan
Andresen, K., Gasim, S., Elhassan, A. M., Khalil, E. A., Barker, D. C., Theander, Thor Grundtvig & Kharazmi, A., 1997, In: Tropical Medicine & International Health. 2, 5, p. 440-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dichotomy in the human CD4+ T-cell response to Leishmania parasites
Kemp, M., Kurtzhals, Jørgen, Kharazmi, A. & Theander, Thor Grundtvig, 1994, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 102, 2, p. 81-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dichotomy of the T cell response to Leishmania antigens in patients suffering from cutaneous leishmaniasis; absence or scarcity of Th1 activity is associated with severe infections
Gaafar, A., Kharazmi, A., Ismail, A., Kemp, M., Hey, A., Christensen, C. B., Dafalla, M., el Kadaro, A. Y., el Hassan, A. M. & Theander, Thor Grundtvig, 1995, In: Clinical and Experimental Immunology. 100, 2, p. 239-45 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dichotomy of the human T cell response to Leishmania antigens. II. Absent or Th2-like response to gp63 and Th1-like response to lipophosphoglycan-associated protein in cells from cured visceral leishmaniasis patients
Kurtzhals, Jørgen, Hey, A. S., Jardim, A., Kemp, M., Schaefer, K. U., Odera, E. O., Christensen, C. B., Githure, J. I., Olafson, R. W. & Theander, Thor Grundtvig, 1994, In: Clinical and Experimental Immunology. 96, 3, p. 416-21 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dichotomy of the human T cell response to Leishmania antigens. I. Th1-like response to Leishmania major promastigote antigens in individuals recovered from cutaneous leishmaniasis
Kemp, M., Hey, A. S., Kurtzhals, Jørgen, Christensen, C. B., Gaafar, A., Mustafa, M. D., Kordofani, A. A., Ismail, A., Kharazmi, A. & Theander, Thor Grundtvig, 1994, In: Clinical and Experimental Immunology. 96, 3, p. 410-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differences in PfEMP1s recognized by antibodies from patients with uncomplicated or severe malaria
Duffy, M. F., Noviyanti, R., Tsuboi, T., Feng, Z., Trianty, L., Sebayang, B. F., Takashima, E., Sumardy, F., Lampah, D. A., Turner, Louise, Lavstsen, Thomas, Fowkes, F. J. I., Siba, P., Rogerson, S. J., Theander, Thor Grundtvig, Marfurt, J., Price, R. N., Anstey, N. M., Brown, G. V. & Papenfuss, A. T., 2016, In: Malaria Journal. 15, 12 p., 258.Research output: Contribution to journal › Journal article › Research › peer-review
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Differences in human antibody reactivity to Plasmodium falciparum variant surface antigens are dependent on age and malaria transmission intensity in northeastern Tanzania
Vestergaard, L. S., Lusingu, J. P., Nielsen, Morten Agertoug, Mmbando, B. P., Dodoo, D., Akanmori, B. D., Alifrangis, Michael, Bygbjerg, Ib Christian, Lemnge, M. M., Staalsoe, T., Hviid, Lars & Theander, Thor Grundtvig, 2008, In: Infection and Immunity. 76, 6, p. 2706-14 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential T-cell expression of LFA-1 in residents from Africa and Denmark. Description of the phenomenon and its possible basis
Hviid, Lars, Elhassan, I. M., Dodoo, D., Jensen, J. B., Bygbjerg, Ib Christian, Satti, G. M. & Theander, Thor Grundtvig, 1994, In: Immunology Letters. 39, 2, p. 147-51 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential expression of var gene groups is associated with morbidity caused by Plasmodium falciparum infection in Tanzanian children
Rottmann, M., Lavstsen, Thomas, Mugasa, J. P., Kaestli, M., Jensen, Anja Ramstedt, Müller, D., Theander, Thor Grundtvig & Beck, H., 2006, In: Infection and Immunity. 74, 7, p. 3904-11 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential induction of functional IgG using the Plasmodium falciparum placental malaria vaccine candidate VAR2CSA
Pinto, V. V., Ditlev, S. B., Jensen, K. E., Resende, M., Dahlbäck, M., Andersen, G., Andersen, P., Theander, Thor Grundtvig, Salanti, Ali & Nielsen, Morten Agertoug, 1 Jan 2011, In: P L o S One. 6, 3, p. e17942Research output: Contribution to journal › Journal article › Research › peer-review
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Differential induction of immunoglobulin G to Plasmodium falciparum variant surface antigens during the transmission season in Daraweesh, Sudan
Nielsen, Morten Agertoug, Grevstad, B., A-Elgadir, T. M. E., Kurtzhals, Jørgen, Giha, H., Staalsoe, T., Hviid, Lars & Theander, Thor Grundtvig, 2005, In: Journal of Infectious Diseases. 192, 3, p. 520-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential patterns of human immunoglobulin G subclass responses to distinct regions of a single protein, the merozoite surface protein 1 of Plasmodium falciparum
Cavanagh, D. R., Dobaño, C., Elhassan, I. M., Marsh, K., Elhassan, A., Hviid, Lars, Khalil, E. A., Theander, Thor Grundtvig, Arnot, D. E. & McBride, J. S., 2001, In: Infection and Immunity. 69, 2, p. 1207-11 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Discovery of oxygenated chalcoes as novel antimalarial agents
Kharazmi, A., Chen, M., Theander, Thor Grundtvig & Christensen, Søren Brøgger, 1997, In: Annals of Tropical Medicine and Parasitology. 91, p. S91-S95 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Discovery of oxygentade chalcones as novel antimalarial agents
Kharazmi, A., Chen, M., Theander, Thor Grundtvig & Christensen, Søren Brøgger, 1997, In: Annals of Tropical Medicine and Parasitology. 91, SUPPL. 1, p. S91-S95Research output: Contribution to journal › Journal article › Research › peer-review
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Diversity among Leishmania isolates from the Sudan: isoenzyme homogeneity of L. donovani versus heterogeneity of L. major
Ibrahim, M. E., Evans, D. A., Theander, Thor Grundtvig, el Hassan, A. M. & Kharazmi, A., 1995, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 89, 4, p. 366-9 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dynamics of PfEMP1 Antibody Profile From Birth to 12 Months of Age in Beninese Infants
Moussiliou, A., Turner, Louise, Cottrell, G., Doritchamou, J., Gbédandé, K., Fievet, N., Luty, A. J. F., Massougbodji, A., Theander, Thor Grundtvig, Deloron, P., Lavstsen, Thomas & Tuikue Ndam, N., 2020, In: The Journal of Infectious Diseases. 221, 12, p. 2010-2017 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dynamics of anti-VAR2CSA immunoglobulin G response in a cohort of senegalese pregnant women
Tuikue Ndam, N. G., Salanti, Ali, Le-Hesran, J., Cottrell, G., Fievet, N., Turner, Louise, Sow, S., Dangou, J., Theander, Thor Grundtvig & Deloron, P., 2006, In: Journal of Infectious Diseases. 193, 5, p. 713-20 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of antimalarial drugs on stimulation and interleukin 2 production of human lymphocytes
Bygbjerg, Ib Christian, Svenson, M., Theander, Thor Grundtvig & Bendtzen, K., 1987, In: International Immunopharmacology. 9, 4, p. 513-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of intermittent treatment with amodiaquine on anaemia and malarial fevers in infants in Tanzania: a randomised placebo-controlled trial
Massaga, J. J., Kitua, A. Y., Lemnge, M. M., Akida, J. A., Malle, L. N., Rønn, A. M., Theander, Thor Grundtvig & Bygbjerg, Ib Christian, 2003, In: Lancet. 361, 9372, p. 1853-60 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of praziquantel on human lymphocyte proliferation in vitro
Ødum, Niels, Theander, Thor Grundtvig & Bygbjerg, Ib Christian, 1984, In: European Journal of Clinical Pharmacology. 27, 3, p. 311-3 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of pyrimethamine and sulphadoxine on human lymphocyte proliferation
Bygbjerg, Ib Christian, Ødum, Niels & Theander, Thor Grundtvig, 1986, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 80, 2, p. 295-300 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of chloroquine, mefloquine and quinine on natural killer cell activity in vitro. An analysis of the inhibitory mechanism
Pedersen, Bente Klarlund, Bygbjerg, Ib Christian, Theander, Thor Grundtvig & Andersen, B. J., 1986, In: Allergy. European Journal of Allergy and Clinical Immunology. 41, 7, p. 537-42 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Efficacy and Safety of the RTS,S/AS01 Malaria Vaccine during 18 Months after Vaccination: A Phase 3 Randomized, Controlled Trial in Children and Young Infants at 11 African Sites
Theander, Thor Grundtvig, Lusingu, J. P. A. & RTS,S Clinical Trials Partnership, R. C. T. P., Jul 2014, In: P L o S Medicine (Online). 11, 7, p. 1-24 24 p., e1001685.Research output: Contribution to journal › Journal article › Research › peer-review
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Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial
RTS,S Clinical Trials Partnership, R. C. T. P., 4 Jul 2015, In: Lancet. 386, 9988, p. 31-45 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Eleven years of malaria surveillance in a Sudanese village highlights unexpected variation in individual disease susceptibility and outbreak severity
Creasey, A., Giha, H., Hamad, A. A., El Hassan, I. M., Theander, Thor Grundtvig & Arnot, D. E., 2004, In: Parasitology. 129, Pt 3, p. 263-71 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Endothelial protein C receptor binding induces conformational changes to severe malaria-associated group A PfEMP1
Raghavan, Sai Sundar Rajan, Turner, Louise, Jensen, R. W., Johansen, Nicolai Tidemand, Jensen, D. S., Gourdon, Pontus Emanuel, Zhang, J., Wang, Y., Theander, Thor Grundtvig, Wang, Kaituo & Lavstsen, Thomas, 2023, In: Structure. 31, 10, p. 1174-1183.e4Research output: Contribution to journal › Journal article › Research › peer-review
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Enhancement of human natural cytotoxicity by Plasmodium falciparum antigen activated lymphocytes
Theander, Thor Grundtvig, Pedersen, Bente Klarlund, Bygbjerg, Ib Christian, Jepsen, S., Larsen, P. B. & Kharazmi, A., 1987, In: Acta Tropica. 44, 4, p. 415-22 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Epitope mapping and topographic analysis of VAR2CSA DBL3X involved in P. falciparum placental sequestration
Dahlbäck, M., Rask, T. S., Andersen, P. H., Nielsen, Morten Agertoug, Ndam, N. T., Resende, M., Turner, Louise, Deloron, P., Hviid, Lars, Lund, O., Pedersen, A. G., Theander, Thor Grundtvig & Salanti, Ali, 2006, In: PLoS Pathogens. 2, 11, p. e124Research output: Contribution to journal › Journal article › Research › peer-review
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Evaluation of the polymerase chain reaction in the diagnosis of cutaneous leishmaniasis due to Leishmania major: a comparison with direct microscopy of smears and sections from lesions
Andresen, K., Gaafar, A., El-Hassan, A. M., Ismail, A., Dafalla, M., Theander, Thor Grundtvig & Kharazmi, A., 1996, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 90, 2, p. 133-5 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evidence for in vitro and in vivo expression of the conserved VAR3 (type 3) plasmodium falciparum erythrocyte membrane protein 1
Wang, Christian William, Lavstsen, Thomas, Bengtsson, D. C., Magistrado, P. A., Berger, S. S., Marquard, A. M., Alifrangis, Michael, Lusingu, J. P., Theander, Thor Grundtvig & Turner, Louise, 2012, In: Malaria Journal. 11, 1, p. 129Research output: Contribution to journal › Journal article › Research › peer-review
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Evidence for the involvement of VAR2CSA in pregnancy-associated malaria
Salanti, Ali, Dahlbäck, M., Turner, Louise, Nielsen, Morten Agertoug, Barfod, Lea Klingenberg, Magistrado, P., Jensen, Anja Ramstedt, Lavstsen, Thomas, Ofori, M. F., Marsh, K., Hviid, Lars & Theander, Thor Grundtvig, 2004, In: Journal of Experimental Medicine. 200, 9, p. 1197-203 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evidence of endothelial inflammation, T cell activation, and T cell reallocation in uncomplicated Plasmodium falciparum malaria
Elhassan, I. M., Hviid, Lars, Satti, G., Akerstrom, B., Jakobsen, P. H., Jensen, J. B. & Theander, Thor Grundtvig, 1994, In: American Journal of Tropical Medicine and Hygiene. 51, 3, p. 372-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Expression of Plasmodium falciparum erythrocyte membrane protein 1 in experimentally infected humans
Lavstsen, Thomas, Magistrado, P., Hermsen, C. C., Salanti, Ali, Jensen, Anja Ramstedt, Sauerwein, R., Hviid, Lars, Theander, Thor Grundtvig & Staalsoe, T., 2005, In: Malaria Journal. 4, 1, p. 21Research output: Contribution to journal › Journal article › Research › peer-review
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Expression of a type B RIFIN in Plasmodium falciparum merozoites and gametes
Mwakalinga, S. B., Wang, Christian William, Bengtsson, D. C., Turner, Louise, Dinko, B., Lusingu, J. P., Arnot, D. E., Sutherland, C. J., Theander, Thor Grundtvig & Lavstsen, Thomas, 2012, In: Malaria Journal. 11, 1, p. 429Research output: Contribution to journal › Journal article › Research › peer-review
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Expression of the domain cassette 8 Plasmodium falciparum erythrocyte membrane protein 1 is associated with cerebral malaria in Benin
Bertin, G. I., Lavstsen, Thomas, Guillonneau, F., Doritchamou, J., Wang, Christian William, Jespersen, Jakob Schmidt, Ezimegnon, S., Fievet, N., Alao, M. J., Lalya, F., Massougbodji, A., Ndam, N. T., Theander, Thor Grundtvig & Deloron, P., 2013, In: P L o S One. 8, 7, p. e68368Research output: Contribution to journal › Journal article › Research › peer-review
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FOETAL for NCD-FOetal Exposure and Epidemiological Transitions: the role of Anaemia in early Life for Non-Communicable Diseases in later life: a prospective preconception study in rural Tanzania
Hjort, L., Lykke Møller, S., Minja, D., Msemo, O., Nielsen, B. B., Christensen, Dirk Lund, Theander, Thor Grundtvig, Nielsen, K., Larsen, L. G., Grunnet, Louise Groth, Groop, L., Prasad, R., Lusingu, J., Schmiegelow, Christentze & Bygbjerg, Ib Christian, 2019, In: BMJ Open. 9, 5, 14 p., e024861.Research output: Contribution to journal › Journal article › Research › peer-review
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Factors associated with and causes of perinatal mortality in northeastern Tanzania
Schmiegelow, Christentze, Minja, D., Oesterholt, M., Pehrson, Caroline, Suhrs, H. E., Boström, S., Lemnge, M., Magistrado, P., Rasch, V., Lusingu, J., Theander, Thor Grundtvig & Nielsen, B. B., Sep 2012, In: Acta Obstetrica et Gynecologica. 91, 9, p. 1061-1068 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Factors associated with and causes of perinatal mortality in northeastern Tanzania
Schmiegelow, Christentze, Minja, D., Oesterholt, M., Pehrson, C., Suhrs, H. E., Boström, S., Lemnge, M., Magistrado, P., Rasch, V., Lusingu, J., Theander, Thor Grundtvig & Nielsen, B. B., 2012, In: Acta Obstetricia et Gynecologica Scandinavica. 91, 9, p. 1061-1068 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children
Agnandji, S. T., Lell, B., Soulanoudjingar, S. S., Fernandes, J. F., Abossolo, B. P., Conzelmann, C., Methogo, B. G. N. O., Doucka, Y., Flamen, A., Mordmüller, B., Issifou, S., Kremsner, P. G., Sacarlal, J., Aide, P., Lanaspa, M., Aponte, J. J., Nhamuave, A., Quelhas, D., Bassat, Q., Mandjate, S. & 31 others, , 2011, In: New England Journal of Medicine. 365, 20, p. 1863-75 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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First-in-human use of a modular capsid virus-like vaccine platform: An open-label, non-randomised, phase 1 clinical trial of the SARS-CoV-2 vaccine ABNCoV2
Smit, M. J., Sander, A. F., Ariaans, M. B. P. A., Fougeroux, C., Heinzel, C., Fendel, R., Esen, M., Kremsner, P. G., Ter Heine, R., Wertheim, H. F., Idorn, M., Paludan, S. R., Underwood, A. P., Binderup, A., Ramirez, S., Bukh, J., Soegaard, M., Erdogan, S. M., Gustavsson, T., Clemmensen, S. & 14 others, , 2023, In: The Lancet Microbe. 4, 3, p. e140-e148Research output: Contribution to journal › Journal article › Research › peer-review
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First-in-human, randomized, double-blind clinical trial of differentially adjuvanted PAMVAC, a vaccine candidate to prevent pregnancy-associated malaria
Mordmüller, B., Sulyok, M., Egger-Adam, D., Resende, M., de Jongh, W. A., Jensen, M. H., Smedegaard, H. H., Ditlev, S. B., Soegaard, M., Poulsen, L., Dyring, C., Calle, C. L., Knoblich, A., Ibáñez, J., Esen, M., Deloron, P., Ndam, N., Issifou, S., Houard, S., Howard, R. F. & 7 others, , 2019, In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 69, 9, p. 1509-1516 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Five-year surveillance of molecular markers of Plasmodium falciparum antimalarial drug resistance in Korogwe District, Tanzania: accumulation of the 581G mutation in the P. falciparum dihydropteroate synthase gene
Alifrangis, Michael, Lusingu, J. P., Mmbando, B., Dalgaard, M. B., Vestergaard, L. S., Ishengoma, D., Khalil, I. F., Theander, Thor Grundtvig, Lemnge, M. M. & Bygbjerg, Ib Christian, 2009, In: American Journal of Tropical Medicine and Hygiene. 80, 4, p. 523-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Freeze-Drying of a Capsid Virus-like Particle-Based Platform Allows Stable Storage of Vaccines at Ambient Temperature
Aves, Kara-Lee, Janitzek, C. M., Fougeroux, Cyrielle Elyette, Theander, Thor Grundtvig & Sander, Adam F. , 2022, In: Pharmaceutics. 14, 6, 1301.Research output: Contribution to journal › Journal article › Research › peer-review
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Full-length recombinant Plasmodium falciparum VAR2CSA binds specifically to CSPG and induces potent parasite adhesion blocking antibodies
Khunrae, P., Dahlbäck, M., Nielsen, Morten Agertoug, Andersen, G., Ditlev, S. B., Resende, M., Pinto, V. V., Theander, Thor Grundtvig, Higgins, M. K. & Salanti, Ali, 2010, In: Journal of Molecular Biology. 397, p. 826-834Research output: Contribution to journal › Journal article › Research › peer-review
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Functional and phenotypic changes in human lymphocytes after coincubation with Leishmania donovani in vitro
Hviid, Lars, Sørensen, A. L., Kharazmi, A. & Theander, Thor Grundtvig, 1990, In: Infection and Immunity. 58, 10, p. 3163-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine
Neafsey, D. E., Juraska, M., Bedford, T., Benkeser, D., Valim, C., Griggs, A., Lievens, M., Abdulla, S., Adjei, S., Agbenyega, T., Agnandji, S. T., Aide, P., Anderson, S., Ansong, D., Aponte, J. J., Asante, K. P., Bejon, P., Birkett, A. J., Bruls, M., Connolly, K. M. & 43 others, , 2015, In: New England Journal of Medicine. 373, 21, p. 2025-37 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Geographical and temporal conservation of antibody recognition of Plasmodium falciparum variant surface antigens
Nielsen, Morten Agertoug, Vestergaard, L. S., Lusingu, J., Kurtzhals, Jørgen, Giha, H. A., Grevstad, B., Goka, B. Q., Lemnge, M. M., Jensen, J. B., Akanmori, B. D., Theander, Thor Grundtvig, Staalsoe, T. & Hviid, Lars, 2004, In: Infection and Immunity. 72, 6, p. 3531-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Haplotypes of the endothelial protein C receptor (EPCR) gene are not associated with severe malaria in Tanzania
Hansson, Helle Smedegaard, Turner, Louise, Møller, L., Wang, Christian William, Minja, D., Gesase, S., Mmbando, B., Bygbjerg, Ib Christian, Theander, Thor Grundtvig, Lusingu, J. P. A., Alifrangis, Michael & Lavstsen, Thomas, 2015, In: Malaria Journal. 14, 9 p., 474.Research output: Contribution to journal › Journal article › Research › peer-review
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Head-to-head comparison of modular vaccines developed using different capsid virus-like particle backbones and antigen conjugation systems
Fredsgaard, L., Goksøyr, L., Thrane, Susan, Aves, Kara-Lee, Theander, Thor Grundtvig & Sander, Adam F. , Jun 2021, In: Vaccines. 9, 6, 11 p., 539.Research output: Contribution to journal › Journal article › Research › peer-review
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Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian children
Cham, G. K. K., Turner, Louise, Kurtis, J. D., Mutabingwa, T., Fried, M., Jensen, Anja Ramstedt, Lavstsen, Thomas, Hviid, Lars, Duffy, P. E. & Theander, Thor Grundtvig, 2010, In: Infection and Immunity. 78, 11, p. 4653-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High efficacy of anti DBL4e-VAR2CSA antibodies in inhibition of CSA-binding Plasmodium falciparum-infected erythrocytes from pregnant women
Magistrado, P. A., Minja, D., Doritchamou, J., Ndam, N. T., John, D., Schmiegelow, Christentze, Massougbodji, A., Dahlbäck, M., Ditlev, S. B., Pinto, V. V., Resende, M., Lusingu, J., Theander, Thor Grundtvig, Salanti, Ali & Nielsen, Morten Agertoug, 2011, In: Vaccine. 29, 3, p. 437-43 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High level of var2csa transcription by Plasmodium falciparum isolated from the placenta
Tuikue Ndam, N. G., Salanti, Ali, Bertin, G., Dahlbäck, M., Fievet, N., Turner, Louise, Gaye, A., Theander, Thor Grundtvig & Deloron, P., 2005, In: Journal of Infectious Diseases. 192, 2, p. 331-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High levels of C-reactive protein in the peripheral blood during visceral leishmaniasis predict subsequent development of post kala-azar dermal leishmaniasis
Gasim, S., Theander, Thor Grundtvig & ElHassan, A. M., 2000, In: Acta Tropica. 75, 1, p. 35-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High levels of plasma IL-10 and expression of IL-10 by keratinocytes during visceral leishmaniasis predict subsequent development of post-kala-azar dermal leishmaniasis
Gasim, S., Elhassan, A. M., Khalil, E. A., Ismail, A., Kadaru, A. M., Kharazmi, A. & Theander, Thor Grundtvig, 1998, In: Clinical and Experimental Immunology. 111, 1, p. 64-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High proportion of subclinical Plasmodium falciparum infections in an area of seasonal and unstable malaria in Sudan
Elhassan, I. M., Hviid, Lars, Jakobsen, P. H., Giha, H., Satti, G. M., Arnot, D. E., Jensen, J. B. & Theander, Thor Grundtvig, 1995, In: American Journal of Tropical Medicine and Hygiene. 53, 1, p. 78-83 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human T-cell recognition of synthetic peptides representing conserved and variant sequences from the merozoite surface protein 2 of Plasmodium falciparum
Theander, Thor Grundtvig, Hviid, Lars, Dodoo, D., Afari, E. A., Jensen, J. B. & Rzepczyk, C. M., 1997, In: Immunology Letters. 58, 1, p. 1-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human genetic polymorphisms in the Knops blood group are not associated with a protective advantage against Plasmodium falciparum malaria in Southern Ghana
Hansson, Helle Smedegaard, Kurtzhals, Jørgen, Goka, B. Q., Rodriques, O. P., Nkrumah, F. N., Theander, Thor Grundtvig, Bygbjerg, Ib Christian & Alifrangis, Michael, 7 Nov 2013, In: Malaria Journal. 12, 1, p. 400Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human infektionsimmunologi. Basalvidenskabelige opdagelser og kliniske konsekvenser
Kemp, M., Pedersen, Bente Klarlund & Theander, Thor Grundtvig, 2000, In: Ugeskrift for læger. 162, 21, p. 3020-3 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA
Barfod, Lea Klingenberg, Bernasconi, N. L., Dahlbäck, M., Jarrossay, D., Andersen, P. H., Salanti, Ali, Ofori, M. F., Turner, Louise, Resende, M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sallusto, F., Lanzavecchia, A. & Hviid, Lars, 2007, In: Molecular Microbiology. 63, 2, p. 335-47 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Humoral and cellular immune responses to glucose regulated protein 78 - a novel Leishmania donovani antigen
Jensen, Anja Ramstedt, Ismail, A., Gaafar, A., El Hassan, A. M. & Theander, Thor Grundtvig, 2002, In: Tropical Medicine & International Health. 7, 5, p. 471-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Humoral and cellular immune responses to synthetic peptides of the Leishmania donovani kinetoplastid membrane protein-11
Jensen, Anja Ramstedt, Gasim, S., Ismail, A., Gaafar, A., Kurtzhals, Jørgen, Kemp, M., El Hassan, A. M., Kharazmi, A. & Theander, Thor Grundtvig, 1998, In: Scandinavian Journal of Immunology. 48, 1, p. 103-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification and characterization of B-cell epitopes in the DBL4e domain of VAR2CSA
Ditlev, S. B., Nielsen, Morten Agertoug, Resende, M., Agerbæk, Mette Ørskov, Pinto, V. V., Andersen, P. H., Magistrado, P., Lusingu, J., Dahlbäck, M., Theander, Thor Grundtvig & Salanti, Ali, 2012, In: P L o S One. 7, 9, p. e43663Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification and localization of a soluble antigen, Ag2, of 136 kDa from Plasmodium falciparum in vitro cultures
Jakobsen, P. H., Grellier, P., Theander, Thor Grundtvig, Behrendt, N., Torii, M., Aikawa, M., Schrevel, J. & Jepsen, S., 1991, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 99, 2, p. 155-62 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of a major rif transcript common to gametocytes and sporozoites of Plasmodium falciparum
Wang, Christian William, Mwakalinga, S. B., Sutherland, C. J., Schwank, S., Sharp, S., Hermsen, C. C., Sauerwein, R. W., Theander, Thor Grundtvig & Lavstsen, Thomas, 2010, In: Malaria Journal. 9, 1, p. 147Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of glycosaminoglycan binding regions in the Plasmodium falciparum encoded placental sequestration ligand, VAR2CSA
Resende, M., Nielsen, Morten Agertoug, Dahlbäck, M., Ditlev, S. B., Andersen, P., Sander, A. F., Ndam, N. T., Theander, Thor Grundtvig & Salanti, Ali, 2008, In: Malaria Journal. 7, p. 104Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IgG antibodies to endothelial protein C receptor-binding Cysteine-rich interdomain region domains of Plasmodium falciparum erythrocyte membrane protein 1 are acquired early in life in individuals exposed to malaria
Turner, Louise, Lavstsen, Thomas, Mmbando, B. P., Wang, Christian William, Magistrado, P. A., Vestergaard, L. S., Ishengoma, D. S., Minja, D. T. R., Lusingu, J. P. & Theander, Thor Grundtvig, Aug 2015, In: Infection and Immunity. 83, 8, p. 3096-103 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IgG responses to Anopheles gambiae salivary antigen gSG6 detect variation in exposure to malaria vectors and disease risk
Stone, W., Bousema, T., Jones, S., Gesase, S., Hashim, R., Gosling, R., Carneiro, I., Chandramohan, D., Theander, Thor Grundtvig, Ronca, R., Modiano, D., Arcà, B. & Drakeley, C., 2012, In: P L o S One. 7, 6, p. e40170Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunization with Recombinant Plasmodium falciparum Erythrocyte Membrane Protein 1 CIDRα1 Domains Induces Domain Subtype Inhibitory Antibodies
Turner, Louise, Theander, Thor Grundtvig & Lavstsen, Thomas, 2018, In: Infection and Immunity. 86, 11, 11 p., e00435-18.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunization with virus-like particles conjugated to CIDRα1 domain of Plasmodium falciparum erythrocyte membrane protein 1 induces inhibitory antibodies
Harmsen, C., Turner, Louise, Thrane, Susan, Sander, Adam F. , Theander, Thor Grundtvig & Lavstsen, Thomas, 2020, In: Malaria Journal. 19, 1, 11 p., 132.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunoglobulin G antibody reactivity to a group A Plasmodium falciparum erythrocyte membrane protein 1 and protection from P. falciparum malaria
Magistrado, P. A., Lusingu, J., Vestergaard, L. S., Lemnge, M., Lavstsen, Thomas, Turner, Louise, Hviid, Lars, Jensen, Anja Ramstedt & Theander, Thor Grundtvig, 2007, In: Infection and Immunity. 75, 5, p. 2415-20 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunopathology of post kala-azar dermal leishmaniasis (PKDL): T-cell phenotypes and cytokine profile
Ismail, A., El Hassan, A. M., Kemp, K., Gasim, S., Kadaru, A. E., Moller, T., Kharazmi, A. & Theander, Thor Grundtvig, 1999, In: Journal of Pathology. 189, 4, p. 615-22 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improving the malaria transmission-blocking activity of a Plasmodium falciparum 48/45 based vaccine antigen by SpyTag/SpyCatcher mediated virus-like display
Singh, S. K., Thrane, Susan, Janitzek, C. M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Theisen, Michael, Salanti, Ali & Sander, Adam F. , 2017, In: Vaccine. 35, 30, p. 3726-3732 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased plasma concentrations of sICAM-1, sVCAM-1 and sELAM-1 in patients with Plasmodium falciparum or P. vivax malaria and association with disease severity
Jakobsen, P. H., Morris-Jones, S., Rønn, A., Hviid, Lars, Theander, Thor Grundtvig, Elhassan, I. M., Bygbjerg, Ib Christian & Greenwood, B. M., 1994, In: Immunology. 83, 4, p. 665-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased plasma levels of soluble ICAM-1 and ELAM-1 (E-selectin) during acute Plasmodium falciparum malaria
Hviid, Lars, Theander, Thor Grundtvig, Elhassan, I. M. & Jensen, J. B., 1993, In: Immunology Letters. 36, 1, p. 51-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased plasma levels of soluble IL-2R are associated with severe Plasmodium falciparum malaria
Jakobsen, P. H., Morris-Jones, S., Theander, Thor Grundtvig, Hviid, Lars, Hansen, M. B., Bendtzen, K., Ridley, R. G. & Greenwood, B. M., 1994, In: Clinical and Experimental Immunology. 96, 1, p. 98-103 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Induction of adhesion-inhibitory antibodies against placental Plasmodium falciparum parasites by using single domains of VAR2CSA
Nielsen, Morten Agertoug, Pinto, V. V., Resende, M., Dahlbäck, M., Ditlev, S. B., Theander, Thor Grundtvig & Salanti, Ali, 2009, In: Infection and Immunity. 77, 6, p. 2482-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of fumarate reductase in Leishmania major and L. donovani by chalcones
Chen, M., Zhai, L., Christensen, Søren Brøgger, Theander, Thor Grundtvig & Kharazmi, A., 2001, In: Antimicrobial Agents and Chemotherapy. 45, 7, p. 2023-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of human lymphocyte proliferation and cleavage of interleukin-2 by Pseudomonas aeruginosa proteases
Theander, Thor Grundtvig, Kharazmi, A., Pedersen, Bente Klarlund, Christensen, L. D., Tvede, N., Poulsen, Lars K., Ødum, Niels, Svenson, M. & Bendtzen, K., 1988, In: Infection and Immunity. 56, 7, p. 1673-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of human lymphocyte proliferative response by serum from Plasmodium falciparum infected patients
Theander, Thor Grundtvig, Svenson, M., Bygbjerg, Ib Christian, Kharazmi, A., Jepsen, S., Andersen, B. J. & Larsen, P. B., 1987, In: APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. 95, 6, p. 257-63 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insect cells are superior to Escherichia coli in producing malaria proteins inducing IgG targeting PfEMP1 on infected erythrocytes
Victor, M. E., Bengtsson, A., Andersen, G., Bengtsson, D., Lusingu, J. P., Vestergaard, L. S., Arnot, D. E., Theander, Thor Grundtvig, Joergensen, L. & Jensen, Anja Ramstedt, 2010, In: Malaria Journal. 9, p. 325Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insecticide-treated bed nets reduce plasma antibody levels and limit the repertoire of antibodies to Plasmodium falciparum variant surface antigens
Askjaer, N., Maxwell, C., Chambo, W., Staalsoe, T., Nielsen, Morten Agertoug, Hviid, Lars, Curtis, C. & Theander, Thor Grundtvig, 2001, In: Clinical and Vaccine Immunology. 8, 6, p. 1289-91 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interferon-¿ and interleukin-4 in human Leishmania donovani infections
Kemp, M., Kurtzhals, Jørgen, Kharazmi, A. & Theander, Thor Grundtvig, 1993, In: Immunology and Cell Biology. 71 ( Pt 6), p. 583-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interferon-¿ and interleukin-4 production by human T cells recognizing Leishmania donovani antigens separated by SDS-PAGE
Bahrenscheer, J., Kemp, M., Kurtzhals, Jørgen, Gachihi, G. S., Kharazmi, A. & Theander, Thor Grundtvig, 1995, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 103, 2, p. 131-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interferon-¿- and tumour necrosis factor-a-producing cells in humans who are immune to cutaneous leishmaniasis
Kemp, K., Theander, Thor Grundtvig, Hviid, Lars, Garfar, A., Kharazmi, A. & Kemp, M., 1999, In: Scandinavian Journal of Immunology. 49, 6, p. 655-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interleukin-4 and interferon-¿ production by Leishmania stimulated peripheral blood mononuclear cells from nonexposed individuals
Kurtzhals, Jørgen, Kemp, M., Poulsen, L. K., Hansen, M. B., Kharazmi, A. & Theander, Thor Grundtvig, 1995, In: Scandinavian Journal of Immunology. 41, 4, p. 343-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Isolation and characterization of a soluble antigen complex of Plasmodium falciparum with pyrogenic properties
Jakobsen, P. H., Hviid, Lars, Theander, Thor Grundtvig, Riley, E. M., Grellier, P., Bruun, L. S., Dalsgaard, K., Schrevel, J. & Jepsen, S., 1991, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 99, 1, p. 21-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetics of human T-cell expression of LFA-1, IL-2 receptor, and ICAM-1 following antigenic stimulation in vitro
Hviid, Lars, Felsing, A. & Theander, Thor Grundtvig, 1993, In: Journal of Clinical & Laboratory Immunology. 40, 4, p. 163-71 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lack of gender-specific antibody recognition of products from domains of a var gene implicated in pregnancy-associated Plasmodium falciparum malaria
Jensen, Anja Ramstedt, Zornig, H. D., Buhmann, Cæcilie Christine Böck, Salanti, Ali, Koram, K. A., Riley, E. M., Theander, Thor Grundtvig, Hviid, Lars & Staalsoe, T., 2003, In: Infection and Immunity. 71, 7, p. 4193-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Leishmaniasis
Kemp, M. & Theander, Thor Grundtvig, 2000, In: Ugeskrift for læger. 162, 46, p. 6203-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Levels of antibody to conserved parts of Plasmodium falciparum merozoite surface protein 1 in Ghanaian children are not associated with protection from clinical malaria
Dodoo, D., Theander, Thor Grundtvig, Kurtzhals, Jørgen, Koram, K., Riley, E., Akanmori, B. D., Nkrumah, F. K. & Hviid, Lars, 1999, In: Infection and Immunity. 67, 5, p. 2131-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Levels of plasma immunoglobulin G with specificity against the cysteine-rich interdomain regions of a semiconserved Plasmodium falciparum erythrocyte membrane protein 1, VAR4, predict protection against malarial anemia and febrile episodes
Lusingu, J. P. A., Jensen, Anja Ramstedt, Vestergaard, L. S., Minja, D. T., Dalgaard, M. B., Gesase, S., Mmbando, B. P., Kitua, A. Y., Lemnge, M. M., Cavanagh, D., Hviid, Lars & Theander, Thor Grundtvig, 2006, In: Infection and Immunity. 74, 5, p. 2867-75 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Licochalcone A, a new antimalarial agent, inhibits in vitro growth of the human malaria parasite Plasmodium falciparum and protects mice from P. yoelii infection
Chen, M., Theander, Thor Grundtvig, Christensen, Søren Brøgger, Hviid, Lars, Zhai, L. & Kharazmi, A., 1994, In: Antimicrobial Agents and Chemotherapy. 38, 7, p. 1470-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Licochalcone A, a novel antiparasitic agent with potent activity against human pathogenic protozoan species of Leishmania
Chen, M., Christensen, Søren Brøgger, Blom, J., Lemmich, E., Nadelmann, L., Fich, K., Theander, Thor Grundtvig & Kharazmi, A., 1993, In: Antimicrobial Agents and Chemotherapy. 37, 12, p. 2550-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Limited cross-reactivity among domains of the Plasmodium falciparum clone 3D7 erythrocyte membrane protein 1 family
Joergensen, L., Turner, Louise, Magistrado, P., Dahlbäck, M. A., Vestergaard, L. S., Lusingu, J. P., Lemnge, M., Salanti, Ali, Theander, Thor Grundtvig & Jensen, Anja Ramstedt, 2006, In: Infection and Immunity. 74, 12, p. 6778-84 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Limonoids from Khaya senegalensis
Khalid, S., Friedrichsen, G., Kharazmi, A., Theander, Thor Grundtvig, Olsen, C. & Christensen, Søren Brøgger, 1998, In: Phytochemistry. 49, 6, p. 1769-1772 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of cellular immune reactivity during acute Plasmodium falciparum malaria
Hviid, Lars, Theander, Thor Grundtvig, Abu-Zeid, Y. A., Abdulhadi, N. H., Jakobsen, P. H., Saeed, B. O., Jepsen, S., Bayoumi, R. A. & Jensen, J. B., 1991, In: FEMS Microbiology Immunology. 3, 4, p. 219-27 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low parasite specific T cell response in clinically immune individuals with low grade Plasmodium falciparum parasitaemia
Theander, Thor Grundtvig, Bygbjerg, Ib Christian, Jacobsen, L., Jepsen, S., Larsen, P. B. & Kharazmi, A., 1986, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 80, 6, p. 1000-1 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lymphocyte response to purified Plasmodium falciparum antigens during and after malaria
Bygbjerg, Ib Christian, Jepsen, S. & Theander, Thor Grundtvig, 1986, In: Acta Tropica. 43, 1, p. 55-62 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 11256
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Real-time and label free determination of ligand binding-kinetics to primary cancer tissue specimens; a novel tool for the assessment of biomarker targeting
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Bacterial superglue enables easy development of efficient virus-like particle based vaccines
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Placental sequestration of Plasmodium falciparum malaria parasites is mediated by the interaction between VAR2CSA and chondroitin sulfate A on syndecan-1
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