Ole Haagen Nielsen

Ole Haagen Nielsen

Clinical Professor

Member of:

  • Internal Medicine: Gastroenterology and Hepatology


  1. Published

    Impact of red and processed meat and fibre intake on treatment outcomes among patients with chronic inflammatory diseases: protocol for a prospective cohort study of prognostic factors and personalised medicine

    Christensen, R., Heitmann, B. L., Andersen, K. W., Nielsen, O. H., Sørensen, S. B., Jawhara, M., Bygum, A., Hvid, L., Grauslund, J., Wied, J., Glerup, H., Fredberg, U., Villadsen, J. A., Kjær, S. G., Fallingborg, J., Moghadd, S. A. G. R., Knudsen, T., Brodersen, J., Frøjk, J., Dahlerup, J. F. & 21 others, Bojesen, A. B., Sørensen, G. L., Thiel, S., Færgeman, N. J., Brandslund, I., Bennike, T. B., Stensballe, A., Schmidt, E. B., Franke, A., Ellinghaus, D., Rosenstiel, P., Raes, J., Boye, M., Werner, L., Nielsen, C. L., Munk, H. L., Nexoe, A. B., Ellingsen, T., Holmskov, U., Kjeldsen, J. & Andersen, V., 2018, In: BMJ Open. 8, 2, 15 p., :e018166.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Impaired sensitivity to beta 2 integrin-blocking in ICAM-1-mediated neutrophil migration in ulcerative colitis

    Vainer, B., Brimnes, J., Claesson, Mogens Helweg & Nielsen, Ole Haagen, 2001, In: Scandinavian Journal of Gastroenterology. 36, 6, p. 621-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    In vitro Superoxide Production by Peripheral Neutrophils from Patients with Inflammatory Bowel Disease

    Nielsen, Ole Haagen, Berild, D. & Ahnfelt-Rønne, I., 1994, In: Mediators of Inflammation. 3, 2, p. 161-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    In vitro studies on the significance of arachidonate metabolism and other oxidative processes in the inflammatory response of human neutrophils and macrophages. With special reference to chronic inflammatory bowel disease

    Nielsen, Ole Haagen, 1988, In: Scandinavian Journal of Gastroenterology. 150, p. 1-21 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Incidence and prevalence of Crohn's disease in the county of Copenhagen, 1962-87: a sixfold increase in incidence

    Munkholm, Pia, Langholz, Ebbe, Nielsen, Ole Haagen, Kreiner, Svend & Binder, V., Jul 1992, In: Scandinavian Journal of Gastroenterology. 27, 7, p. 609-14 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Incidence and prevalence of ulcerative colitis in Copenhagen county from 1962 to 1987

    Langholz, Ebbe, Munkholm, Pia, Nielsen, Ole Haagen, Kreiner, Svend & Binder, V., Dec 1991, In: Scandinavian Journal of Gastroenterology. 26, 12, p. 1247-56 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Incidence of, phenotypes of and survival from small bowel cancer in Denmark, 1994-2010: a population-based study

    Bojesen, R. D., Andersson, M., Riis, Lene Buhl, Nielsen, Ole Haagen & Jess, T., Sep 2016, In: Journal of Gastroenterology. 51, 9, p. 891-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Increased hepatic urea synthesis in patients with active inflammatory bowel disease

    Lundsgaard, C., Hamberg, O., Thomsen, O. Ø., Nielsen, Ole Haagen & Vilstrup, H., 1 Jan 1996, In: Journal of Hepatology. 24, 5, p. 587-593 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Increased mucosal concentrations of soluble intercellular adhesion molecule-1 (sICAM-1), sE-selectin, and interleukin-8 in active ulcerative colitis

    Nielsen, Ole Haagen, Brynskov, J. & Vainer, B., 1 Jan 1996, In: Digestive Diseases and Sciences. 41, 9, p. 1780-1785 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Increased numbers of interleukin-15-expressing cells in active ulcerative colitis

    Kirman, I. & Nielsen, Ole Haagen, Sep 1996, In: The American Journal of Gastroenterology. 91, 9, p. 1789-94 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Increased risk of atrial fibrillation and stroke during active stages of inflammatory bowel disease: a nationwide study

    Kristensen, S. L., Lindhardsen, J., Ahlehoff, O., Erichsen, R., Lamberts, M., Khalid, U., Torp-Pedersen, C., Nielsen, Ole Haagen, Gislason, Gunnar Hilmar & Hansen, Peter Riis, Apr 2014, In: Europace. 16, 4, p. 477-484 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Increased risk of venous thromboembolism and arterial cardiovascular events in patients with inflammatory bowel disease

    Kristensen, S. L., Ahlehoff, O., Lindhardsen, J., Gislason, Gunnar Hilmar, Nielsen, Ole Haagen & Hansen, Peter Riis, 2012, In: Ugeskrift for Laeger. 174, 48, p. 3003-3006 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Induction of endogenous arachidonic acid metabolism in human neutrophils with snake venom phospholipase A2, immune complexes, and A23187

    Langholz, Ebbe & Nielsen, Ole Haagen, Mar 1990, In: Prostaglandins, Leukotrienes & Essential Fatty Acids. 39, 3, p. 227-9 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Inflammation and free oxygen radicals

    Nielsen, Ole Haagen & Ahnfelt-Ronne, I., 1 Jan 1989, In: Ugeskrift for Laeger. 151, 16, p. 976-978 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Inflammation og frie oxygenradikaler

    Nielsen, Ole Haagen & Ahnfelt-Rønne, I., 1989, In: Nordisk Medicin. 104, 8-9, p. 216-8 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Inflammatorisk tarmsygdom--spiller mikroorganismer en rolle?

    Nielsen, S. E., Nielsen, Ole Haagen, Vainer, B. & Claesson, Mogens Helweg, 2002, In: Ugeskrift for læger. 164, 50, p. 5947-50 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Inflammatory Bowel Disease Is Associated With an Increased Risk of Hospitalization for Heart Failure: a Danish Nationwide Cohort A Danish Nationwide Cohort Study

    Kristensen, S. L., Ahlehoff, O., Lindhardsen, J., Erichsen, R., Lamberts, M., Khalid, U., Nielsen, Ole Haagen, Torp-Pedersen, C., Gislason, G. H. & Hansen, Peter Riis, Sep 2014, In: Circulation: Heart Failure. 7, 5, p. 717-722 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Inflammatory Bowel Disease and Small Bowel Cancer Risk, Clinical Characteristics, and Histopathology: A Population-Based Study

    Bojesen, R. D., Riis, Lene Buhl, Høgdall, Estrid Vilma Solyom, Nielsen, Ole Haagen & Jess, T., Dec 2017, In: Clinical Gastroenterology and Hepatology. 15, 12, p. 1900-1907.e2

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Inflammatory bowel disease with primary sclerosing cholangitis: A Danish population-based cohort study 1977-2011

    Sørensen, J. Ø., Nielsen, Ole Haagen, Andersson, M., Ainsworth, M. A., Ytting, H., Bélard, E. & Jess, T., 2018, In: Liver International. 38, 3, p. 532-541

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Inflammatory bowel disease: potential therapeutic strategies

    Nielsen, Ole Haagen, Vainer, B., Bregenholt, S., Claesson, Mogens Helweg, Bishop, P. D. & Kirman, I., 1997, In: Cytokines Cellular and Molecular Therapy. 3, 4, p. 267-281 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Inflammatory pathways of importance for management of inflammatory bowel disease

    Pedersen, J., Coskun, M., Soendergaard, C., Salem, M. & Nielsen, Ole Haagen, 7 Jan 2014, In: World Journal of Gastroenterology. 20, 1, p. 64-77 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Infliximab: Mechanism of action beyond TNF-α neutralization in inflammatory bowel disease

    Kirman, I., Whelan, R. L. & Nielsen, Ole Haagen, 1 Jul 2004, In: European Journal of Gastroenterology and Hepatology. 16, 7, p. 639-641 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Influence of smoking on colonic gene expression profile in Crohn's disease

    Nielsen, Ole Haagen, Bjerrum, Jakob Tveiten , Csillag, C., Nielsen, Finn Cilius & Olsen, Jørgen, 2009, In: PLoS ONE. 4, 7, p. e6210

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Inhibition of 5-lipoxygenase pathway of arachidonic acid metabolism in human neutrophils by sulfasalazine and 5-aminosalicylic acid

    Nielsen, Ole Haagen, Bukhave, K., Elmgreen, J. & Ahnfelt-Rønne, I., Jun 1987, In: Digestive Diseases and Sciences. 32, 6, p. 577-82 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Inhibition of human neutrophils by auranofin: chemotaxis and metabolism of arachidonate via the 5-lipoxygenase pathway

    Elmgreen, J., Ahnfelt-Rønne, I. & Nielsen, Ole Haagen, Feb 1989, In: Annals of the Rheumatic Diseases. 48, 2, p. 134-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Inhibition of intestinal macrophage chemotaxis to leukotriene B4 by sulphasalazine, olsalazine, and 5-aminosalicylic acid

    Nielsen, Ole Haagen, Verspaget, H. W. & Elmgreen, J., Jun 1988, In: Alimentary Pharmacology and Therapeutics. 2, 3, p. 203-11 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Inhibitors of apoptosis (IAPs) regulate intestinal immunity and inflammatory bowel disease (IBD) inflammation

    Pedersen, J., LaCasse, E. C., Seidelin, Jakob Benedict, Coskun, M. & Nielsen, Ole Haagen, Nov 2014, In: Trends in Molecular Medicine. 20, 11, p. 652-65 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Insulin-like growth factor binding protein 3 in inflammatory bowel disease

    Kirman, I., Whelan, R. L., Jain, S., Nielsen, S. E., Seidelin, Jakob Benedict & Nielsen, Ole Haagen, Apr 2005, In: Digestive Diseases and Sciences. 50, 4, p. 780-4 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Integration of transcriptomics and metabonomics: improving diagnostics, biomarker identification and phenotyping in ulcerative colitis

    Bjerrum, Jakob Tveiten , Rantalainen, M., Wang, Y., Olsen, Jørgen & Nielsen, Ole Haagen, 2014, In: Metabolomics. 10, 2, p. 280-290 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Integrative Transcriptomic and Metabonomic Molecular Profiling of Colonic Mucosal Biopsies Indicates a Unique Molecular Phenotype for Ulcerative Colitis

    Rantalainen, M., Bjerrum, Jakob Tveiten , Olsen, Jørgen, Nielsen, Ole Haagen & Wang, Y., 2 Jan 2015, In: Journal of Proteome Research. 14, 1, p. 479-90 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Interleukin 10 (Tenovil) in the prevention of postoperative recurrence of Crohn's disease

    Colombel, J. F., Rutgeerts, P., Malchow, H., Jacyna, M., Nielsen, Ole Haagen, Rask-Madsen, J., Van Deventer, S., Ferguson, A., Desreumaux, P., Forbes, A., Geboes, K., Melani, L. & Cohard, M., 12 Jul 2001, In: Gut. 49, 1, p. 42-46 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Interleukin-15 and its role in chronic inflammatory diseases

    Kirman, I., Vainer, B. & Nielsen, Ole Haagen, 28 Aug 1998, In: Inflammation Research. 47, 7, p. 285-289 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  33. Published

    Interleukin-2 receptor alpha and beta chain expression by circulating alpha beta and gamma delta T cells in inflammatory bowel disease

    Kirman, I., Nielsen, Ole Haagen, Kjaersgaard, E. & Brynskov, J., Feb 1995, In: Digestive Diseases and Sciences. 40, 2, p. 291-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Interleukin-4 and 13 induce the expression and release of monocyte chemoattractant protein 1, interleukin-6 and stem cell factor from human detrusor smooth muscle cells: synergy with interleukin-1beta and tumor necrosis factor-alpha

    Bouchelouche, K., Andresen, Lars, Alvarez, S., Nordling, J., Nielsen, Ole Haagen & Bouchelouche, P., 2006, In: Journal of Urology. 175, 2, p. 760-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Intestinal barrier integrity and inflammatory bowel disease: Stem cell-based approaches to regenerate the barrier

    Holmberg, F. E. O., Pedersen, J., Jørgensen, P., Soendergaard, C., Jensen, Kim Bak & Nielsen, Ole Haagen, Apr 2018, In: Journal of Tissue Engineering and Regenerative Medicine. 12, 4

    Research output: Contribution to journalReviewResearchpeer-review

  36. Published

    Intestinal interleukin-8 concentration and gene expression in inflammatory bowel disease

    Nielsen, Ole Haagen, Rüdiger, N., Gaustadnes, M. & Horn, T., 1 Jan 1997, In: Scandinavian Journal of Gastroenterology. 32, 10, p. 1028-1034 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Investigating the Crime Scene—Molecular Signatures in Inflammatory Bowel Disease

    Andersen, V., Bennike, T. B., Bang, C., Rioux, J. D., Hébert-Milette, I., Sato, T., Hansen, Axel Kornerup & Nielsen, Ole Haagen, 2023, In: International Journal of Molecular Sciences. 24, 13, 11217.

    Research output: Contribution to journalReviewResearchpeer-review

  38. Published

    Involvement of CDX2 in the cross talk between TNF-α and Wnt signaling pathway in the colon cancer cell line Caco-2

    Coskun, M., Olsen, A. K., Bzorek, M., Holck, S., Engel, U. H., Nielsen, Ole Haagen & Troelsen, J. T., 2014, In: Carcinogenesis. 35, 5, p. 1185-1192 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Involvement of JAK/STAT signaling in the pathogenesis of inflammatory bowel disease

    Coskun, M., Salem, M., Pedersen, J. & Nielsen, Ole Haagen, 2013, In: Pharmacological Research. 76, p. 1-8 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  40. Published

    Involvement of interleukin-4 and -10 in inflammatory bowel disease

    Nielsen, Ole Haagen, Køppen, T., Rüdiger, N., Horn, T., Eriksen, J. & Kirman, I., Sep 1996, In: Digestive Diseases and Sciences. 41, 9, p. 1786-93 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Involvement of oxygen-derived free radicals in the pathogenesis of chronic inflammatory bowel disease

    Nielsen, Ole Haagen & Ahnfelt-Rønne, I., 15 Dec 1991, In: Wiener Klinische Wochenschrift. 69, 21-23, p. 995-1000 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  42. Published

    Iron replacement therapy: do we need new guidelines?

    Nielsen, Ole Haagen, Coskun, M. & Weiss, G., 2016, In: Current Opinion in Gastroenterology. 32, 2, p. 128-135 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  43. Published

    Kinase Signaling in Colitis-Associated Colon Cancer and Inflammatory Bowel Disease

    Temby, M., Boye, T. L., Hoang, J., Nielsen, Ole Haagen & Gubatan, J., Nov 2023, In: Biomolecules. 13, 11, 14 p., 1620.

    Research output: Contribution to journalReviewResearchpeer-review

  44. Kinetics of 5-aminosalicylic acid after jejunal instillation in man

    Nielsen, Ole Haagen & Bondesen, S., Dec 1983, In: British Journal of Clinical Pharmacology. Supplement. 16, 6, p. 738-40 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Kolorektal cancerudvikling ved colitis ulcerosa

    Kallesøe, J., Langholz, Ebbe, Frisch, M., Bjerrum, J. T. & Nielsen, Ole Haagen, 25 Oct 2010, In: Ugeskrift for Laeger. 172, 43, p. 2960-2 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Kronisk inflammatorisk tarmsygdom i relation til graviditet

    Andreasson, B., Nielsen, Ole Haagen, Bondesen, S., Jacobsen, O. & Jarnum, S., 4 Jun 1984, In: Ugeskrift for Laeger. 146, 23, p. 1708-10 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    LFA-1 subunit expression in ulcerative colitis patients

    Kirman, I. & Nielsen, Ole Haagen, 14 May 1996, In: Digestive Diseases and Sciences. 41, 4, p. 670-676 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Laegers deltagelse i kliniske laegemiddelforsøg

    Nielsen, Ole Haagen & Ainsworth, M., 14 Apr 2003, In: Ugeskrift for Laeger. 165, 16, p. 1639

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Letter: European Medicines Agency recommendations for allergic reactions to intravenous iron-containing medicines

    Gomollõn, F., Chowers, Y., Danese, S., Dignass, A., Nielsen, Ole Haagen, Lakatos, P. L., Lees, C. W., Lindgren, S., Lukas, M., Mantzaris, G. J., Michetti, P., Moum, B., Peyrin-Biroulet, L., Toruner, M., Van Der Woude, J., Weiss, G., Stoevelaar, H. & Reinisch, W., 2014, In: Alimentary Pharmacology and Therapeutics. 39, 7, p. 743-744

    Research output: Contribution to journalComment/debateResearch

  50. Published

    Leukotriene B4 receptor levels and intracellular calcium signalling in polymorphonuclear leukocytes from patients with Crohn's disease

    Bouchelouche, P. N., Berild, D., Nielsen, Ole Haagen, Elmgreen, J. & Poulsen, H. S., Apr 1995, In: European journal of gastroenterology & hepatology. 7, 4, p. 349-56 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 4947702