Lars Hviid
Professor
Centre for Medical Parasitology
CMP
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-11-TR4
Member of:
SURFACE team
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Baculovirus-expressed constructs induce immunoglobulin G that recognizes VAR2CSA on Plasmodium falciparum-infected erythrocytes
Barfod, Lea Klingenberg, Nielsen, Morten Agertoug, Turner, Louise, Dahlbäck, M., Jensen, Anja Ramstedt, Hviid, Lars, Theander, Thor Grundtvig & Salanti, Ali, 2006, In: Infection and Immunity. 74, 7, p. 4357-60 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro Plasmodium falciparum drug sensitivity assay: inhibition of parasite growth by incorporation of stomatocytogenic amphiphiles into the erythrocyte membrane
Ziegler, H. L., Stærk, Dan, Christensen, J., Hviid, Lars, Hägerstrand, H. & Jaroszewski, J. W., 2002, In: Antimicrobial Agents and Chemotherapy. 46, 5, p. 1441-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro selection of Plasmodium falciparum 3D7 for expression of variant surface antigens associated with severe malaria in African children
Staalsoe, T., Nielsen, Morten Agertoug, Vestergaard, L. S., Jensen, Anja Ramstedt, Theander, Thor Grundtvig & Hviid, Lars, 2003, In: Parasite Immunology. 25, 8-9, p. 421-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vivo switching between variant surface antigens in human Plasmodium falciparum infection
Staalsoe, T., Hamad, A. A., Hviid, Lars, Elhassan, I. M., Arnot, D. E. & Theander, Thor Grundtvig, 2002, In: Journal of Infectious Diseases. 186, 5, p. 719-22 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Leishmania-specific T cells expressing interferon-¿(IFN-¿) and IL-10 upon activation are expanded in individuals cured of visceral leishmaniasis
Kemp, K., Kemp, M., Kharazmi, A., Ismail, A., Kurtzhals, Jørgen, Hviid, Lars & Theander, Thor Grundtvig, 1999, In: Clinical and Experimental Immunology. 116, 3, p. 500-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes
Jensen, Anja Ramstedt, Magistrado, P., Sharp, S., Joergensen, L., Lavstsen, Thomas, Chiucchiuini, A., Salanti, Ali, Vestergaard, L. S., Lusingu, J. P., Hermsen, R., Sauerwein, R., Christensen, J., Nielsen, Morten Agertoug, Hviid, Lars, Sutherland, C., Staalsoe, T. & Theander, Thor Grundtvig, 2004, In: Journal of Experimental Medicine. 199, 9, p. 1179-90 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum parasites expressing pregnancy-specific variant surface antigens adhere strongly to the choriocarcinoma cell line BeWo
Haase, R. N., Megnekou, R., Lundquist, M., Ofori, M. F., Hviid, Lars & Staalsoe, T., 2006, In: Infection and Immunity. 74, 5, p. 3035-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum variant surface antigen expression varies between isolates causing severe and nonsevere malaria and is modified by acquired immunity
Nielsen, Morten Agertoug, Staalsoe, T., Kurtzhals, Jørgen, Goka, B. Q., Dodoo, D., Alifrangis, Michael, Theander, Thor Grundtvig, Akanmori, B. D. & Hviid, Lars, 2002, In: Journal of Immunology. 168, 7, p. 3444-50 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum: VAR2CSA expressed during pregnancy-associated malaria is partially resistant to proteolytic cleavage by trypsin
Nielsen, Morten Agertoug, Resende, M., Alifrangis, Michael, Turner, Louise, Hviid, Lars, Theander, Thor Grundtvig & Salanti, Ali, 2007, In: Experimental Parasitology. 117, 1, p. 1-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro selection for adhesion of Plasmodium falciparum-infected erythrocytes to ABO antigens does not affect PfEMP1 and RIFIN expression
van der Puije, W., Wang, Christian William, Sudharson, S., Hempel, C., Olsen, Rebecca Wendelboe, Dalgaard, Nanna, Ofori, M. F., Hviid, Lars, Kurtzhals, Jørgen & Staalsø, Trine, 2020, In: Scientific Reports. 10, 1, p. 12871 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum infection and naturally acquired immunity to malaria antigens among Ghanaian children in northern Ghana
Seidu, Zakaria, Lamptey, H., Lopez-Perez, Mary, Whittle, N. O., Oppong, S. K., Kyei-Baafour, E., Pobee, A. N. A., Adjei, G. O., Hviid, Lars & Ofori, M. F., 2023, In: Parasite Epidemiology and Control. 22, p. e00317Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum-infected erythrocyte knob density is linked to the PfEMP1 variant expressed
Subramani, R., Quadt, K., Jeppesen, A. E., Hempel, C., Petersen, J. E. V., Hassenkam, Tue, Hviid, Lars & Barfod, Lea Klingenberg, 2015, In: mBio. 6, 5, 7 p., e01456-15.Research output: Contribution to journal › Journal article › Research › peer-review
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A Novel Domain Cassette Identifies Plasmodium falciparum PfEMP1 Proteins Binding ICAM-1 and Is a Target of Cross-Reactive, Adhesion-Inhibitory Antibodies
Bengtsson, A., Joergensen, L., Rask, T. S., Olsen, R. W., Andersen, M. A., Turner, Louise, Theander, Thor Grundtvig, Hviid, Lars, Higgins, M. K., Craig, A., Brown, A. & Jensen, Anja Ramstedt, 2013, In: Journal of Immunology. 190, 1, p. 240-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A conformational epitope in placental malaria vaccine antigen VAR2CSA: What does it teach us?
Doritchamou, J. Y. A., Renn, J. P., Hviid, Lars & Duffy, P. E., 2023, In: PLoS Pathogens. 19, 5, e1011370.Research output: Contribution to journal › Journal article › Research › peer-review
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A longitudinal study of human antibody responses to Plasmodium falciparum rhoptry-associated protein 1 in a region of seasonal and unstable malaria transmission
Fonjungo, P. N., Elhassan, I. M., Cavanagh, D. R., Theander, Thor Grundtvig, Hviid, Lars, Roper, C., Arnot, D. E. & McBride, J. S., 1999, In: Infection and Immunity. 67, 6, p. 2975-85 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A longitudinal study of type-specific antibody responses to Plasmodium falciparum merozoite surface protein-1 in an area of unstable malaria in Sudan
Cavanagh, D. R., Elhassan, I. M., Roper, C., Robinson, V. J., Giha, H., Holder, A. A., Hviid, Lars, Theander, Thor Grundtvig, Arnot, D. E. & McBride, J. S., 1998, In: Journal of Immunology. 161, 1, p. 347-59 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A new portable device for automatic controlled-gradient cryopreservation of blood mononuclear cells
Hviid, Lars, Albeck, G., Hansen, B., Theander, Thor Grundtvig & Talbot, A., 1993, In: Journal of Immunological Methods. 157, 1-2, p. 135-42 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A sub-family of common and highly conserved Plasmodium falciparum var genes
Salanti, Ali, Jensen, Anja Ramstedt, Zornig, H. D., Staalsoe, T., Joergensen, L., Nielsen, Morten Agertoug, Khattab, A., Arnot, D. E., Klinkert, M. Q., Hviid, Lars & Theander, Thor Grundtvig, 2002, In: Molecular and Biochemical Parasitology. 122, 1, p. 111-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A vaccine targeted specifically to prevent cerebral malaria - is there hope?
Hviid, Lars, Lavstsen, Thomas & Jensen, Anja Ramstedt, Jul 2018, In: Expert Review of Vaccines. 17, 7, p. 565-567 3 p.Research output: Contribution to journal › Letter › Research › peer-review
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Acquisition and decay of IgM and IgG responses to merozoite antigens after Plasmodium falciparum malaria in Ghanaian children
Walker, Melanie Rose, Knudsen, Anne Schlitterlau, Partey, Frederica Dedo, Bassi, Maria Rosaria, Frank, A. M., Castberg, F. C., Sarbah, E. W., Ofori, M. F., Hviid, Lars & Barfod, Lea Klingenberg, 2020, In: PLoS ONE. 15, 12, p. e0243943Research output: Contribution to journal › Journal article › Research › peer-review
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Acquisition and decay of antibodies to pregnancy-associated variant antigens on the surface of Plasmodium falciparum-infected erythrocytes that protect against placental parasitemia
Staalsoe, T., Megnekou, R., Fievét, N., Ricke, C. H., Zornig, H. D., Leke, R., Taylor, D. W., Deloron, P. & Hviid, Lars, 2001, In: Journal of Infectious Diseases. 184, 5, p. 618-26 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Acquisition of IgG to ICAM-1-Binding DBLβ Domains in the Plasmodium falciparum erythrocyte membrane protein 1 antigen family varies between Groups A, B, and C
Olsen, Rebecca Wendelboe, Ecklu-Mensah, G., Bengtsson, A., Ofori, M. F., Kusi, K. A., Koram, K. A., Hviid, Lars, Adams, Yvonne & Jensen, Anja Ramstedt, 2019, In: Infection and Immunity. 87, 10, e00224-19.Research output: Contribution to journal › Journal article › Research › peer-review
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Activation of CD8-positive suppressor cells during the malaria season
Theander, Thor Grundtvig, Hviid, Lars, Abu-Zeid, Y. A., Abdulhadi, N. H., Saeed, B. O., Jakobsen, P. H., Jepsen, S., Bayoumi, R. A. & Jensen, J. B., 1993, In: Immunology and Infectious Diseases. 3, p. 97-102Research output: Contribution to journal › Journal article › Research › peer-review
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Activation of human T lymphocytes by Leishmania lipophosphoglycan
Kemp, M., Theander, Thor Grundtvig, Handman, E., Hey, A. S., Kurtzhals, Jørgen, Hviid, Lars, Sørensen, A. L., Were, J. O., Koech, D. K. & Kharazmi, A., 1991, In: Scandinavian Journal of Immunology. 33, 2, p. 219-24 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Acute P. falciparum malaria induces a loss of CD28- T IFN-¿ producing cells
Kemp, K., Akanmori, B. D., Kurtzhals, J. A. L., Adabayeri, V., Goka, B. Q. & Hviid, Lars, 2002, In: Parasite Immunology. 24, 11-12, p. 545-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Adhesion specificities of Plasmodium falciparum-infected erythrocytes involved in the pathogenesis of pregnancy-associated malaria
Hviid, Lars, 2007, In: American Journal of Pathology. 170, 6, p. 1817-9 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination
Larsen, M. D., Lopez-Perez, Mary, Dickson, E. K., Ampomah, P., Tuikue Ndam, N., Nouta, J., Koeleman, C. A. M., Ederveen, A. L. H., Mordmüller, B., Salanti, Ali, Nielsen, Morten Agertoug, Massougbodji, A., van der Schoot, C. E., Ofori, M. F., Wuhrer, M., Hviid, Lars & Vidarsson, G., 2021, In: Nature Communications. 12, 5838.Research output: Contribution to journal › Journal article › Research › peer-review
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Aligned hemozoin crystals in curved clusters in malarial red blood cells revealed by nanoprobe X-ray Fe fluorescence and diffraction
Kapishnikov, S., Berthing, T., Hviid, Lars, Dierolf, M., Menzel, A., Pfeiffer, F., Als-Nielsen, Jens & Leiserowitz, L., 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 28, p. 11184-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Alkamides from Phyllanthus fraternus
Sittie, A. A., Lemmich, E., Olsen, C. E., Hviid, Lars & Christensen, Søren Brøgger, 1998, In: Planta Medica. 64, 2, p. 192-3 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Anaemia caused by asymptomatic Plasmodium falciparum infection in semi-immune African schoolchildren
Kurtzhals, Jørgen, Addae, M. M., Akanmori, B. D., Dunyo, S., Koram, K. A., Appawu, M. A., Nkrumah, F. K. & Hviid, Lars, 1999, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 93, 6, p. 623-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis by flow cytometry of α2-macroglobulin and nonimmune IgM-binding to Plasmodium falciparum-infected erythrocytes
Hviid, Lars & Lopez-Perez, Mary, 2022, Malaria Immunology: Targeting the Surface of Infected Erythrocytes. Humana Press, Vol. 2470. p. 435-444 10 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Analysis of IgG with specificity for variant surface antigens expressed by placental Plasmodium falciparum isolates
Khattab, A., Reinhardt, C., Staalsoe, T., Fievet, N., Kremsner, P. G., Deloron, P., Hviid, Lars & Klinkert, M., 2004, In: Malaria Journal. 3, p. 21Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of allelic cross-reactivity of monoclonal IgG antibodies by a multiplexed reverse FluoroSpot assay
Hoffmann-Veltung, H., Anabire, Nsoh Godwin, Ofori, M. F., Janhmatz, P., Ahlborg, N., Hviid, Lars & Quintana Varon, Maria del Pilar, 2022, In: eLife. 11, p. e79245Research output: Contribution to journal › Journal article › Research › peer-review
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Anti-phosphatidylserine antibody levels are low in multigravid pregnant women in a malaria-endemic area in Nigeria, and do not correlate with anti-VAR2CSA antibodies
Fasanya, A., Mohammed, N., Saleh, B. H., Tijani, M. K., Teleka, A., Quintana Varon, Maria del Pilar, Hviid, Lars & Persson, K. E. M., 2023, In: Frontiers in Cellular and Infection Microbiology. 13, 1130186.Research output: Contribution to journal › Journal article › Research › peer-review
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Anti-phospholipid antibodies in patients with Plasmodium falciparum malaria
Jakobsen, P. H., Morris-Jones, S. D., Hviid, Lars, Theander, Thor Grundtvig, Høier-Madsen, M., Bayoumi, R. A. & Greenwood, B. M., 1993, In: Immunology. 79, 4, p. 653-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibodies to the N-terminal block 2 of Plasmodium falciparum merozoite surface protein 1 are associated with protection against clinical malaria
Cavanagh, D. R., Dodoo, D., Hviid, Lars, Kurtzhals, Jørgen, Theander, Thor Grundtvig, Akanmori, B. D., Polley, S., Conway, D. J., Koram, K. & McBride, J. S., 2004, In: Infection and Immunity. 72, 11, p. 6492-502 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibodies to variable Plasmodium falciparum-infected erythrocyte surface antigens are associated with protection from novel malaria infections
Giha, H. A., Staalsoe, T., Dodoo, D., Roper, C., Satti, G. M., Arnot, D. E., Hviid, Lars & Theander, Thor Grundtvig, 2000, In: Immunology Letters. 71, 2, p. 117-26 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibodies to variant antigens on the surfaces of infected erythrocytes are associated with protection from malaria in Ghanaian children
Dodoo, D., Staalsoe, T., Giha, H., Kurtzhals, Jørgen, Akanmori, B. D., Koram, K., Dunyo, S., Nkrumah, F. K., Hviid, Lars & Theander, Thor Grundtvig, 2001, In: Infection and Immunity. 69, 6, p. 3713-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibody reactivities to glutamate-rich peptides of Plasmodium falciparum parasites in humans from areas of different malaria endemicity
Jakobsen, P. H., Theander, Thor Grundtvig, Hviid, Lars, Morris-Jones, S., Jensen, J. B., Bayoumi, R. A., Greenwood, B. M., Bygbjerg, Ib Christian & Heegaard, P. M., 1996, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 104, 10, p. 734-40 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibody responses to Rhoptry-Associated Protein-1 (RAP-1) of Plasmodium falciparum parasites in humans from areas of different malaria endemicity
Jakobsen, P. H., Kurtzhals, Jørgen, Riley, E. M., Hviid, Lars, Theander, Thor Grundtvig, Morris-Jones, S., Jensen, J. B., Bayoumi, R. A., Ridley, R. G. & Greenwood, B. M., 1997, In: Parasite Immunology. 19, 9, p. 387-93 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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B-cell responses to pregnancy-restricted and -unrestricted Plasmodium falciparum erythrocyte membrane protein 1 antigens in Ghanaian women naturally exposed to malaria parasites
Ampomah, P., Stevenson, L., Ofori, M. F., Barfod, Lea Klingenberg & Hviid, Lars, May 2014, In: Infection and Immunity. 82, 5, p. 1860-71 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Binding of human serum proteins to Plasmodium falciparum-infected erythrocytes and its association with malaria clinical presentation
Lopez-Perez, Mary, van der Puije, W., Castberg, F. C., Ofori, M. F. & Hviid, Lars, 2020, In: Malaria Journal. 19, 1, 362.Research output: Contribution to journal › Journal article › Research › peer-review
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Biochemical characterization, localization and immunostimulating properties of a soluble glycoprotein, Ag1, isolated from in vitro cultures of Plasmodium falciparum
Jakobsen, P. H., Jepsen, S., Riley, E. M., Theander, Thor Grundtvig, Grellier, P., Lihme, A., Hviid, Lars, Dziegiel, Morten Hanefeld & Schrevel, J., 1990, In: Parasitology Reseach. 76, 8, p. 657-61 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biomarker of Anopheles exposure in Ghanaian children with hemoglobin S and C
Londono-Renteria, B., Seidu, Zakaria, Lamptey, H., Ofori, M. F., Hviid, Lars & Lopez-Perez, Mary, 2024, In: Acta Tropica. 249, 8 p., 107043.Research output: Contribution to journal › Journal article › Research › peer-review
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Blood outgrowth endothelial cells (BOECs) as a novel tool for studying adhesion of Plasmodium falciparum-infected erythrocytes
Ecklu-Mensah, G., Olsen, Rebecca Wendelboe, Bengtsson, A., Ofori, M. F., Hviid, Lars, Jensen, Anja Ramstedt & Adams, Yvonne, 2018, In: PLoS ONE. 13, 10, 12 p., e0204177.Research output: Contribution to journal › Journal article › Research › peer-review
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CCR3 expression induced by IL-2 and IL-4 functioning as a death receptor for B cells
Jinquan, T., Jacobi, H. H., Jing, C., Millner, A., Sten, E., Hviid, Lars, Anting, L., Ryder, L. P., Glue, C., Skov, P. S., Jarman, E., Lamberth, K., Malling, H. & Poulsen, Lars K., 2003, In: Journal of Immunology. 171, 4, p. 1722-31 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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CD36 selection of 3D7 Plasmodium falciparum associated with severe childhood malaria results in reduced VAR4 expression
Magistrado, P., Staalsoe, T., Theander, Thor Grundtvig, Hviid, Lars & Jensen, Anja Ramstedt, 2008, In: Malaria Journal. 7, 1, p. 204Research output: Contribution to journal › Journal article › Research › peer-review
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Cell-mediated immune responses to Plasmodium falciparum purified soluble antigens in sickle-cell trait subjects
Bayoumi, R. A., Abu-Zeid, Y. A., Abdulhadi, N. H., Saeed, B. O., Theander, Thor Grundtvig, Hviid, Lars, Ghalib, H. W., Nugud, A. H., Jepsen, S. & Jensen, J. B., 1990, In: Immunology Letters. 25, 1-3, p. 243-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cell-mediated immune responses to soluble Plasmodium falciparum antigens in residents from an area of unstable malaria transmission in the Sudan
Hviid, Lars, Theander, Thor Grundtvig, Jakobsen, P. H., Abu-Zeid, Y. A., Abdulhadi, N. H., Saeed, B. O., Jepsen, S., Bayoumi, R. A. L., Bendtzen, K. & Jensen, J. B., 1990, In: APMIS. 98, 7-12, p. 594-604 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cell-mediated immunity to Plasmodium falciparum infection: evidence against the involvement of cytotoxic lymphocytes
Theander, Thor Grundtvig, Andersen, B. J., Pedersen, B. K., Jepsen, S., Bygbjerg, Ib Christian, Hviid, Lars, Larsen, P. B. & Kharazmi, A., 1988, In: Scandinavian Journal of Immunology. 28, 1, p. 105-11 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1-based vaccines to prevent it
Jensen, Anja Ramstedt, Adams, Yvonne & Hviid, Lars, 2020, In: Immunological Reviews. 293, 1, p. 230-252Research output: Contribution to journal › Review › Research › peer-review
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Changes in var gene mRNA levels during erythrocytic development in two phenotypically distinct Plasmodium falciparum parasites
Dahlbäck, M., Lavstsen, Thomas, Salanti, Ali, Hviid, Lars, Arnot, D. E., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2007, In: Malaria Journal. 6, p. 78Research output: Contribution to journal › Journal article › Research › peer-review
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Chondroitin sulfate A-adhering Plasmodium falciparum-infected erythrocytes express functionally important antibody epitopes shared by multiple variants
Barfod, Lea Klingenberg, Dobrilovic, T., Magistrado, P., Khunrae, P., Viwami, F., Bruun, J., Dahlbäck, M., Bernasconi, N. L., Fried, M., John, D., Duffy, P. E., Salanti, Ali, Lanzavecchia, A., Lim, C. T., Ndam, N. T., Higgins, M. K. & Hviid, Lars, 2010, In: Journal of Immunology. 185, 12, p. 7553-61 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Clinical and laboratory characteristics of children with sickle cell disease on hydroxyurea treated with artemether-lumefantrine for acute uncomplicated malaria
Segbefia, C., Amponsah, S. K., Afrane, A. K. A., Nyarko, M. Y., Brew, Y., Salifu, N., Ahorhorlu, S. Y., Sulley, A. M., Hviid, Lars, Ofori, M. F. & Adjei, G. O., 2023, In: Frontiers in Medicine. 10, p. 1291330Research output: Contribution to journal › Journal article › Research › peer-review
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Clinical disease, immunity and protection against Plasmodium falciparum malaria in populations living in endemic areas
Hviid, Lars, 1998, In: Expert Reviews in Molecular Medicine. 1998, p. 1-10 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Complement binding to erythrocytes is associated with macrophage activation and reduced haemoglobin in Plasmodium falciparum malaria
Goka, B. Q., Kwarko, H., Kurtzhals, Jørgen, Gyan, B., Ofori-Adjei, E., Ohene, S. A., Hviid, Lars, Akanmori, B. D. & Neequaye, J., 2001, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 95, 5, p. 545-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Compounds useful in the diagnosis and treatment of pregnancy-associated malaria
Theander, Thor Grundtvig, Salanti, Ali, Hviid, Lars, Staalsø, Trine, Jensen, Anja Ramstedt, Lavstsen, Thomas & Dahlbäck, M., 2004, Patent No. WO2004067559 A1, Priority date 27 Jan 2003, Priority No. WO2004067559 A1Research output: Patent
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Comprehensive analysis of Fc-mediated IgM binding to the Plasmodium falciparum erythrocyte membrane protein 1 family in three parasite clones
Quintana Varon, Maria del Pilar, Ecklu-Mensah, G., Tcherniuk, S. O., Ditlev, S. B., Oleinikov, A. V., Hviid, Lars & Lopez-Perez, Mary, 2019, In: Scientific Reports. 9, 1, 11 p., 6050.Research output: Contribution to journal › Journal article › Research › peer-review
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Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA
Raghavan, Sai Sundar Rajan, Dagil, Robert, Lopez-Perez, Mary, Conrad, J., Bassi, Maria Rosaria, Quintana Varon, Maria del Pilar, Choudhary, Swati, Gustavsson, Tobias, Wang, Y., Gourdon, Pontus Emanuel, Ofori, M. F., Christensen, S. B., Minja, D. T. R., Schmiegelow, Christentze, Nielsen, Morten Agertoug, Barfod, Lea Klingenberg, Hviid, Lars, Salanti, Ali, Lavstsen, Thomas & Wang, Kaituo, 2022, In: PLoS Pathogens. 18, 11, e1010924.Research output: Contribution to journal › Journal article › Research › peer-review
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Cytokine production and apoptosis among T cells from patients under treatment for Plasmodium falciparum malaria
Kemp, K., Akanmori, B. D., Adabayeri, V., Goka, B. Q., Kurtzhals, Jørgen, Behr, C. & Hviid, Lars, 2002, In: Clinical and Experimental Immunology. 127, 1, p. 151-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cytokine response to pregnancy-associated recrudescence of Plasmodium berghei infection in mice with pre-existing immunity to malaria
Megnekou, R., Staalsø, Trine & Hviid, Lars, 1 Nov 2013, In: Malaria Journal. 12, 1, p. 387Research output: Contribution to journal › Journal article › Research › peer-review
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Dansk malariaforskning fra spæd begyndelse til international styrkeposition
Jepsen, M. P. G., Jepsen, S., Kurtzhals, Jørgen & Hviid, Lars, 2017, In: Ugeskrift for Laeger. 179, 20, p. 866-869 V10160756.Research output: Contribution to journal › Journal article › Research › peer-review
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Detection of antibodies to variant antigens on Plasmodium falciparum-infected erythrocytes by flow cytometry
Staalsoe, T., Giha, H. A., Dodoo, D., Theander, Thor Grundtvig & Hviid, Lars, 1999, In: Cytometry. Part B: Clinical Cytometry. 35, 4, p. 329-36 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Detection of very low level Plasmodium falciparum infections using the nested polymerase chain reaction and a reassessment of the epidemiology of unstable malaria in Sudan
Roper, C., Elhassan, I. M., Hviid, Lars, Giha, H., Richardson, W., Babiker, H., Satti, G. M., Theander, Thor Grundtvig & Arnot, D. E., 1996, In: American Journal of Tropical Medicine and Hygiene. 54, 4, p. 325-31 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Developing Plasmodium falciparum malaria vaccines for populations living in areas with stable parasite transmission
Hviid, Lars & Theander, Thor Grundtvig, 2007, In: International Journal of Biotechnology. 9, 3/4, p. 292-300 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Development of vaccines against Plasmodium falciparum malaria: taking lessons from naturally acquired protective immunity
Hviid, Lars, 2007, In: Microbes and Infection. 9, 6, p. 772-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differences in human antibody reactivity to Plasmodium falciparum variant surface antigens are dependent on age and malaria transmission intensity in northeastern Tanzania
Vestergaard, L. S., Lusingu, J. P., Nielsen, Morten Agertoug, Mmbando, B. P., Dodoo, D., Akanmori, B. D., Alifrangis, Michael, Bygbjerg, Ib Christian, Lemnge, M. M., Staalsoe, T., Hviid, Lars & Theander, Thor Grundtvig, 2008, In: Infection and Immunity. 76, 6, p. 2706-14 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential T-cell expression of LFA-1 in residents from Africa and Denmark. Description of the phenomenon and its possible basis
Hviid, Lars, Elhassan, I. M., Dodoo, D., Jensen, J. B., Bygbjerg, Ib Christian, Satti, G. M. & Theander, Thor Grundtvig, 1994, In: Immunology Letters. 39, 2, p. 147-51 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential induction of immunoglobulin G to Plasmodium falciparum variant surface antigens during the transmission season in Daraweesh, Sudan
Nielsen, Morten Agertoug, Grevstad, B., A-Elgadir, T. M. E., Kurtzhals, Jørgen, Giha, H., Staalsoe, T., Hviid, Lars & Theander, Thor Grundtvig, 2005, In: Journal of Infectious Diseases. 192, 3, p. 520-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential patterns of human immunoglobulin G subclass responses to distinct regions of a single protein, the merozoite surface protein 1 of Plasmodium falciparum
Cavanagh, D. R., Dobaño, C., Elhassan, I. M., Marsh, K., Elhassan, A., Hviid, Lars, Khalil, E. A., Theander, Thor Grundtvig, Arnot, D. E. & McBride, J. S., 2001, In: Infection and Immunity. 69, 2, p. 1207-11 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distinct patterns of cytokine regulation in discrete clinical forms of Plasmodium falciparum malaria
Akanmori, B. D., Kurtzhals, Jørgen, Goka, B. Q., Adabayeri, V., Ofori, M. F., Nkrumah, F. K., Behr, C. & Hviid, Lars, 2000, In: European Cytokine Network. 11, 1, p. 113-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of pregnancy and intensity of Plasmodium falciparum transmission on immunoglobulin G subclass responses to variant surface antigens
Megnekou, R., Staalsoe, T., Taylor, D. W., Leke, R. & Hviid, Lars, 2005, In: Infection and Immunity. 73, 7, p. 4112-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elevated levels of nitric oxide and low levels of haptoglobin are associated with severe malarial anaemia in African children
Gyan, B., Kurtzhals, Jørgen, Akanmori, B. D., Ofori, M., Goka, B. Q., Hviid, Lars & Behr, C., 2002, In: Acta Tropica. 83, 2, p. 133-40 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endemic Burkitt lymphoma - an aggressive childhood cancer linked to Plasmodium falciparum exposure, but not to exposure to other malaria parasites
Quintana Varon, Maria del Pilar, Smith-Togobo, C., Moormann, A. & Hviid, Lars, 2020, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 128, 2, p. 129-135Research output: Contribution to journal › Review › Research › peer-review
- Published
Enzyme-linked immunosorbent assay for activation of the classical complement pathway by Plasmodium falciparum-infected erythrocyte surface antigen-specific antibodies
Larsen, M. D., Bayarri-Olmos, R., Garred, Peter & Hviid, Lars, 2022, In: Methods in Molecular Biology. 2470, p. 673-678 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epitope mapping and topographic analysis of VAR2CSA DBL3X involved in P. falciparum placental sequestration
Dahlbäck, M., Rask, T. S., Andersen, P. H., Nielsen, Morten Agertoug, Ndam, N. T., Resende, M., Turner, Louise, Deloron, P., Hviid, Lars, Lund, O., Pedersen, A. G., Theander, Thor Grundtvig & Salanti, Ali, 2006, In: PLoS Pathogens. 2, 11, p. e124Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Etiology of placental Plasmodium falciparum malaria in African women
Ofori, M. F., Lamptey, H., Dickson, E. K., Kyei-Baafour, E. & Hviid, Lars, 2018, In: The Journal of Infectious Diseases. 218, 2, p. 277-281 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evasion of classical complement pathway activation on Plasmodium falciparum-infected erythrocytes opsonized by PfEMP1-specific IgG
Larsen, M. D., Quintana Varon, Maria del Pilar, Ditlev, S. B., Bayarri-Olmos, R., Ofori, M. F., Hviid, Lars & Garred, Peter, 2019, In: Frontiers in Immunology. 9, 3088.Research output: Contribution to journal › Journal article › Research › peer-review
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Evasion of immunity to Plasmodium falciparum malaria by IgM masking of protective IgG epitopes in infected erythrocyte surface-exposed PfEMP1
Barfod, Lea Klingenberg, Dalgaard, M. B., Pleman, S. T., Ofori, M. F., Pleass, R. J. & Hviid, Lars, 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 30, p. 12485-90 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evidence for the involvement of VAR2CSA in pregnancy-associated malaria
Salanti, Ali, Dahlbäck, M., Turner, Louise, Nielsen, Morten Agertoug, Barfod, Lea Klingenberg, Magistrado, P., Jensen, Anja Ramstedt, Lavstsen, Thomas, Ofori, M. F., Marsh, K., Hviid, Lars & Theander, Thor Grundtvig, 2004, In: Journal of Experimental Medicine. 200, 9, p. 1197-203 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evidence of endothelial inflammation, T cell activation, and T cell reallocation in uncomplicated Plasmodium falciparum malaria
Elhassan, I. M., Hviid, Lars, Satti, G., Akerstrom, B., Jakobsen, P. H., Jensen, J. B. & Theander, Thor Grundtvig, 1994, In: American Journal of Tropical Medicine and Hygiene. 51, 3, p. 372-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Expression of Plasmodium falciparum erythrocyte membrane protein 1 in experimentally infected humans
Lavstsen, Thomas, Magistrado, P., Hermsen, C. C., Salanti, Ali, Jensen, Anja Ramstedt, Sauerwein, R., Hviid, Lars, Theander, Thor Grundtvig & Staalsoe, T., 2005, In: Malaria Journal. 4, 1, p. 21Research output: Contribution to journal › Journal article › Research › peer-review
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Expression of variant surface antigens by Plasmodium falciparum parasites in the peripheral blood of clinically immune pregnant women indicates ongoing placental infection
Ofori, M. F., Staalsoe, T., Bam, V., Lundquist, M., David, K. P., Browne, E. N. L., Akanmori, B. D. & Hviid, Lars, 2003, In: Infection and Immunity. 71, 3, p. 1584-6 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Frequency of electrocardiographic alterations and pericardial effusion in patients with uncomplicated malaria
Kaagaard, M. D., Matos, L. O., Holm, A. E., Gomes, L. C., Wegener, A., Lima, K. O., Vieira, I. V. M., de Souza, R. M., Marinho, C. R. F., Hviid, Lars, Vestergaard, L. S., Dominguez, Helena, Biering-Sørensen, Tor, Silvestre, O. M. & Brainin, P., 2022, In: American Journal of Cardiology. 165, p. 116-123Research output: Contribution to journal › Journal article › Research › peer-review
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Functional and phenotypic changes in human lymphocytes after coincubation with Leishmania donovani in vitro
Hviid, Lars, Sørensen, A. L., Kharazmi, A. & Theander, Thor Grundtvig, 1990, In: Infection and Immunity. 58, 10, p. 3163-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Functional antibodies against placental malaria parasites are variant dependent and differ by geographic region
Doritchamou, J., Teo, A., Morrison, R., Arora, G., Kwan, J., Manzella-Lapeira, J., Medina-Maldonado, S., Langhorne, J., Hviid, Lars, Narum, D. L., Dicko, A., Fried, M. & Duffy, P. E., 2019, In: Infection and Immunity. 87, 7, 14 p., e00865-18.Research output: Contribution to journal › Journal article › Research › peer-review
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Geographical and temporal conservation of antibody recognition of Plasmodium falciparum variant surface antigens
Nielsen, Morten Agertoug, Vestergaard, L. S., Lusingu, J., Kurtzhals, Jørgen, Giha, H. A., Grevstad, B., Goka, B. Q., Lemnge, M. M., Jensen, J. B., Akanmori, B. D., Theander, Thor Grundtvig, Staalsoe, T. & Hviid, Lars, 2004, In: Infection and Immunity. 72, 6, p. 3531-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Haptoglobin 1-1 is associated with susceptibility to severe Plasmodium falciparum malaria
Quaye, I. K., Ekuban, F. A., Goka, B. Q., Adabayeri, V., Kurtzhals, Jørgen, Gyan, B., Ankrah, N. A., Hviid, Lars & Akanmori, B. D., 2000, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 94, 2, p. 216-9 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heart failure associated with imported malaria: A nationwide Danish cohort study
Brainin, P., Mohr, G. H., Modin, D., Claggett, B., Silvestre, O. M., Shah, A., Vestergaard, L. S., Jensen , Jens-Ulrik Stæhr , Hviid, Lars, Torp-Pedersen, Christian, Køber, Lars Valeur, Solomon, S., Schou, Morten, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2021, In: ESC heart failure. 8, 5, p. 3521-3529Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian children
Cham, G. K. K., Turner, Louise, Kurtis, J. D., Mutabingwa, T., Fried, M., Jensen, Anja Ramstedt, Lavstsen, Thomas, Hviid, Lars, Duffy, P. E. & Theander, Thor Grundtvig, 2010, In: Infection and Immunity. 78, 11, p. 4653-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High burden of asymptomatic malaria and anaemia despite high adherence to malaria control measures: a cross-sectional study among pregnant women across two seasons in a malaria-endemic setting in Ghana
Anabire, Nsoh Godwin, Aculley, B., Pobee, A., Kyei-Baafour, E., Awandare, G. A., Quintana Varon, Maria del Pilar, Hviid, Lars & Ofori, M. F., 2023, In: Infection. 51, 6, p. 1717-1729Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High frequencies of tumor-infiltrating and circulating γδ T cells in endemic Burkitt lymphoma patients
Smith-Togobo, C., Quintana Varon, Maria del Pilar, Ofori, M. F. & Hviid, Lars, 2019, In: American Journal of Tropical Medicine and Hygiene. 101, S5, p. 563-563 1830.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
High frequency of circulating ¿d T cells with dominance of the vd1 subset in a healthy population
Hviid, Lars, Akanmori, B. D., Loizon, S., Kurtzhals, Jørgen, Ricke, C. H., Lim, A., Koram, K. A., Nkrumah, F. K., Mercereau-Puijalon, O. & Behr, C., 2000, In: International Immunology. 12, 6, p. 797-805 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High proportion of subclinical Plasmodium falciparum infections in an area of seasonal and unstable malaria in Sudan
Elhassan, I. M., Hviid, Lars, Jakobsen, P. H., Giha, H., Satti, G. M., Arnot, D. E., Jensen, J. B. & Theander, Thor Grundtvig, 1995, In: American Journal of Tropical Medicine and Hygiene. 53, 1, p. 78-83 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human T-cell recognition of synthetic peptides representing conserved and variant sequences from the merozoite surface protein 2 of Plasmodium falciparum
Theander, Thor Grundtvig, Hviid, Lars, Dodoo, D., Afari, E. A., Jensen, J. B. & Rzepczyk, C. M., 1997, In: Immunology Letters. 58, 1, p. 1-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human Vδ1+ T cells in the immune response to Plasmodium falciparum infection
Hviid, Lars, Smith-Togobo, C. & Willcox, B. E., 2019, In: Frontiers in Immunology. 10, 5 p., 259.Research output: Contribution to journal › Review › Research › peer-review
- Published
Human monoclonal IgG selection of Plasmodium falciparum for the expression of placental malaria-specific variant surface antigens
Soerli, J., Barfod, Lea Klingenberg, Lavstsen, Thomas, Bernasconi, N. L., Lanzavecchia, A. & Hviid, Lars, 2009, In: Parasite Immunology. 31, 6, p. 341-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA
Barfod, Lea Klingenberg, Bernasconi, N. L., Dahlbäck, M., Jarrossay, D., Andersen, P. H., Salanti, Ali, Ofori, M. F., Turner, Louise, Resende, M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sallusto, F., Lanzavecchia, A. & Hviid, Lars, 2007, In: Molecular Microbiology. 63, 2, p. 335-47 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ICAM-1-binding Plasmodium falciparum erythrocyte membrane protein 1 variants elicits opsonic-phagocytosis IgG responses in Beninese children
Suurbaar, Jennifer, Moussiliou, A., Tahar, R., Olsen, Rebecca Wendelboe, Adams, Yvonne, Dalgaard, Nanna, Baafour, E. K., Adukpo, S., Hviid, Lars, Kusi, K. A., Alao, J., Ofori, M. F., Ndam, N. T. & Jensen, Anja Ramstedt, 2022, In: Scientific Reports. 12, 12994.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IgG responses to the Plasmodium falciparum antigen VAR2CSA in Colombia are restricted to pregnancy and are not induced by exposure to Plasmodium vivax
Lopez-Perez, Mary, Larsen, M. D., Bayarri-Olmos, R., Ampomah, P., Stevenson, L., Arévalo-Herrera, M., Herrera, S. & Hviid, Lars, 2018, In: Infection and Immunity. 86, 8, e00136-18.Research output: Contribution to journal › Journal article › Research › peer-review
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Kinetics of B Cell responses to Plasmodium falciparum erythrocyte membrane protein 1 in Ghanaian women naturally exposed to malaria parasites
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Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites
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B-cell responses to pregnancy-restricted and -unrestricted Plasmodium falciparum erythrocyte membrane protein 1 antigens in Ghanaian women naturally exposed to malaria parasites
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