David Paul Drucker Woldbye
Associate Professor
Neuropharm and Genetics
Blegdamsvej 3, 2200 København N.
- 1993
- Published
Electroconvulsive shock (ECS) does not facilitate the development of kindling
Kragh, J., Bruhn, T., Woldbye, David Paul Drucker & Bolwig, T. G., 1993, In: Progress in Neuro-Psychopharmacology & Biological Psychiatry. 17, p. 985-989Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Electroconvulsive shock and lidocaine-induced seizures in the rat activate astrocytes as measured by glial fibrillary acidic protein
Kragh, J., Bolwig, T. G., Woldbye, David Paul Drucker & Jørgensen, O. S., 1993, In: Biological Psychiatry. 33, p. 794-800Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-term effect of repeated electroconvulsive shock on exploratory behaviour and seizure susceptibility to lidocaine in rats
Kragh, J., Woldbye, David Paul Drucker & Bolwig, T. T., 1993, In: Journal of Psychiatric Research. 27, p. 89-94Research output: Contribution to journal › Journal article › Research › peer-review
- 1994
- Published
A dual-immunocytochemical method to localize c-fos protein in specific neurons based on their content of neuropeptides and connectivity.
Mikkelsen, J. D., Larsen, Jacob, Sørensen, G. G., Woldbye, David Paul Drucker, Bolwig, T. G., Hastings, M. H. & Ebling, F. J., 1994, In: Histochemistry. 101, 4, p. 245-51 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Electroconvulsive shocks increase the expression of neuropeptide Y (NPY) mRNA in the piriform cortex and the dentate gyrus
Mikkelsen, J. D., Woldbye, David Paul Drucker, Kragh, J., Larsen, P. J. & Bolwig, T. G., 1994, In: Molecular Brain Research. 23, p. 317-322Research output: Contribution to journal › Journal article › Research › peer-review
- 1996
- Published
Neuropeptide Y inhibits hippocampal seizures and wet dog shakes.
Woldbye, David Paul Drucker, Madsen, T. M., Larsen, Jacob, Mikkelsen, J. D. & Bolwig, T. G., 1996, In: Brain Research. 737, 1-2, p. 162-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No Loss of somatostatin-immunoreactive neurons in the hippocampal dentate hilus of alcohol-withdrawal kindled rats
Ulrichsen, J., Woldbye, David Paul Drucker, Olsen, C. H., Haugbøl, S., Bolwig, T. G. & Hemmingsen, R., 1996, In: Alcohol & Alcoholism. 31, 4, p. 411-419Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No loss of hippocampal hilar somatostatinergic neurons after repeated electroconvulsive shock: a combined stereological and in situ hybridization study
Dalby, N. O., Tonder, N., Woldbye, David Paul Drucker, West, M., Finsen, B. & Bolwig, T. G., 1996, In: Biological Psychiatry. 40 (1), p. 54-60Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prolonged induction of c-fos in neuropeptide Y- and somatostatin-immunoreactive neurons of the rat dentate gyrus after electroconvulsive stimulation.
Woldbye, David Paul Drucker, Greisen, M. H., Bolwig, T. G., Larsen, Jacob & Mikkelsen, J. D., 1996, In: Brain Research. 720, 1-2, p. 111-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synaptic degeneration and remodelling after fast kindling of the olfactory bulb.
Woldbye, David Paul Drucker, Bolwig, T. G., Kragh, J. & Jørgensen, O. S., 1996, In: Neurochemical Research. 21, 5, p. 585-93 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1997
- Published
Powerful inhibition of kainic acid seizures by neuropeptide Y via Y5-like receptors
Woldbye, David Paul Drucker, Larsen, P. J., Mikkelsen, J. D., Klemp, K., Madsen, T. M. & Bolwig, T. G., 1997, In: Nature Medicine. 3, 7, p. 761-764Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
- Published
Antiepileptic effects of NPY on pentylenetetrazole seizures
Woldbye, David Paul Drucker, 1998, In: Regulatory Peptides. 75-76, p. 279-282Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antisense oligonucleotide to GABAA receptor 2 subunit induces limbic status epilepticus
Karle, J., Woldbye, David Paul Drucker, Elster, L., Diemer, N. H., Bolwig, T. G., Olsen, R. W. & Nielsen, M., 1998, In: Journal of Neuroscience Research. 54, p. 863-869Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Electrical amygdala kindling in alcohol-withdrawal kindled rats
Ulrichsen, J., Woldbye, David Paul Drucker, Madsen, T. M., Clemmesen, L., Haugbøl, S., Olsen, C. H., Laursen, H., Bolwig, T. G. & Hemmingsen, R., 1998, In: Alcohol & Alcoholism. 33, 3, p. 244-254Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuropeptide Y Attenuates Naloxone-Precipitated Morphine Withdrawal via Y5-like Receptors
Woldbye, David Paul Drucker, Klemp, K. & Madsen, T. M., 1998, In: Journal of Pharmacology and Experimental Therapeutics. 284, no. 2, p. 633-636Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The how and Y of eating
Woldbye, David Paul Drucker & Larsen, P. J., 1998, In: Nature Medicine. Vol 4, No 6, p. 671-672Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
- Published
Electroconvulsive therapy as an anticonvulsant: A possible role of neuropeptide Y (NPY)
Bolwig, T. G., Woldbye, David Paul Drucker & Mikkelsen, J. D., 1999, In: Journal of ECT. 15, 1, p. 93-101Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kainic acid seizure suppression by neuropeptide Y is not correlated to immediate early gene mRNA levels in rats
Madsen, T. M., Woldbye, David Paul Drucker, Bolwig, T. G. & Mikkelsen, J. D., 1999, In: Neuroscience Letters. 271, p. 21-24Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
- Published
GABAA receptor antisense epilepsy: histological changes following infusion of antisense oligodeoxynucleotide to GABAA receptor gamma 2 subunit into rat hippocampus
Karle, J., Woldbye, David Paul Drucker & Diemer, N. H., 2001, In: Neurological Research. 23, p. 39-46Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibitory effect of neuropeptide Y on morphine withdrawal is accompanied by reduced c-fos expression in specific brain regions
Clausen, T. R., Møller, M. & Woldbye, David Paul Drucker, 2001, In: Journal of Neuroscience Research. 64, 4, p. 410-417Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Repeated inhibitory effects of NPY on hippocampal CA3 seizures and wet dog shakes
Klemp, K. & Woldbye, David Paul Drucker, 2001, In: Peptides. 22, 3, p. 523-527Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
Ethanol withdrawal in rats is attenuated by intracerebroventricular administration of neuropeptide Y
Woldbye, David Paul Drucker, Ulrichsen, J., Haugbøl, S. & Bolwig, T. G., 2002, In: Alcohol & Alcoholism. 37(4), p. 318-21Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuropeptide Y
Woldbye, David Paul Drucker, 2002, In: Molekulyarnaya Meditsina. 5, p. 2246-50Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuropeptide Y inhibits in vitro epileptiform activity in the entorhinal cortex of mice
Woldbye, David Paul Drucker, Nanobashvili, A., Husum, H., Bolwig, T. G. & Kokaia, M., 2002, In: Neurosc. Lett.. 333, 2, p. 127-30Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
Role for M5 muscarinic acetylcholine receptors in cocaine addiction
Fink-Jensen, A., Fedorova, I., Wörtwein, Gitta, Woldbye, David Paul Drucker, Rasmussen, T., Thomsen, M., Bolwig, T. G., Knitowski, K. M., McKinzie, D. L., Yamada, M., Wess, J. & Basile, A., 2003, In: Journal of Neuroscience Research. 74, 1, p. 91-6Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
Neuropeptide Y Y5 receptors suppress in vitro spontaneous epileptiform in the rat hippocampus
Nanobashvili, A., Woldbye, David Paul Drucker, Husum, H., Bolwig, T. G. & Kokaia, M., 2004, In: NeuroReport. 15, 2, p. 339-43Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuropeptide Y and seizures: effects of exogenously applied ligands
Woldbye, David Paul Drucker & Kokaia, M., 2004, In: Neuropeptides. Vol. 38, no.4, p. 253-60Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential roles for neuropeptide Y Y1 and Y5 receptors in anxiety and sedation
Sørensen, G., Lindberg, C., Wörtwein, Gitta, Bolwig, T. G., Woldbye, David Paul Drucker & Sørensen, G., 1 Sep 2004, In: Journal of Neuroscience Research. 77, 5, p. 723-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Reduced cocaine self-administration in muscarinic M5 acetylcholine receptor-deficient mice
Thomsen, M. M., Woldbye, David Paul Drucker, Wörtwein, Gitta, Fink-Jensen, A., Wess, J. & Caine, S. B., 2005, In: Journal of Neuroscience. Vol. 25, p. 8141-49Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of activity-regulated cytoskeleton protein (Arc) mRNA after acute and chronic electroconvulsive stimulation in the rat.
Larsen, M. H., Olesen, M., Woldbye, David Paul Drucker, Hay-Schmidt, Anders, Hansen, H. H., Rønn, L. C. B. & Mikkelsen, J. D., 2005, In: Brain Research. 1064, 1-2, p. 161-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The short/long polymorphism in the serotonin transporter gene promoter is not associated with panic disorder in a Scandinavian sample
Olesen, O. F., Bennike, B. G., Steno-Hansen, E., Koefoed, P., Woldbye, David Paul Drucker, Bolwig, T. G. & Mellerup, Erling Thyge, 2005, In: Psychiatric Genetics. Vol. 15, p. 159Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential suppression of seizures via Y2 and Y5 neuropeptide Y receptors
Woldbye, David Paul Drucker, Nanobashvili, A., Sørensen, Andreas Toft, Husum, H., Bolwig, T. G., Sørensen, G., Ernfors, P., Kokaia, M. & Sørensen, G., 1 Dec 2005, In: Neurobiology of Disease. 20, 3, p. 760-72 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Accumulated increase in neuropeptide Y and somatostatin gene expression of the rat in response to repeated electroconvulsive stimulation
Mikkelsen, J. D. & Woldbye, David Paul Drucker, 2006, In: Journal of Psychiatric Research. 40, 2, p. 153-159 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No association between the -399 C > T polymorphism of the neuropeptide Y gene and schizophrenia, unipolar depression or panic disorder in a Danish population
Lindberg, C., Koefoed, P., Hansen, E. S., Bolwig, T. G., Rehfeld, J. F., Mellerup, E., Jorgensen, O. S., Kessing, L. V., Werge, T., Haugbol, S., Wang, A. G. & Woldbye, David Paul Drucker, 2006, In: Acta Psychiatrica Scandinavica. 113, 1, p. 54-58 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unaltered neuropeptide Y (NPY)-stimulated [35S]GTPgamma-S binding suggests a net increase in NPY signalling after repeated electroconvulsive seizures in mice
Christensen, D. Z., Olesen, M. V., Kristiansen, H., Mikkelsen, J. D. & Woldbye, David Paul Drucker, 2006, In: Journal of Neuroscience Research. 84, 6, p. 1282-1291 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Decreased gene expression of neuropeptide Y and its receptors in hippocampal regions during ethanol withdrawal in rats
Olling, J. D., Ulrichsen, J., Haugbøl, S., Glenthøj, Birte Yding, Hemmingsen, R. & Woldbye, David Paul Drucker, 2007, In: Neuroscience Letters. 424, 3, p. 160-164 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Decreased prepulse inhibition and increased sensitivity to muscarinic, but not dopaminergic drugs in M-5 muscarinic acetylcholine receptor knockout mice
Thomsen, M., Wortwein, G., Fink-Jensen, Anders, Woldbye, David Paul Drucker, Wess, J. & Caine, S. B., 2007, In: Psychopharmacology. 192, 1, p. 97-110 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Involvement of Y5 receptors in neuropeptide Y agonist-induced analgesic-like effect in the rat hot plate test
Thomsen, M., Wörtwein, Gitta, Olesen, M. V., Begtrup, M., Havez, S., Bolwig, T. G. & Woldbye, David Paul Drucker, 2007, In: Brain Research. 1155, p. 49-55Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein kinase C activity blocks neuropeptide Y-mediated inhibition of glutamate release and contributes to excitability of the hippocampus in status epilepticus
Silva, A. P., Lourenco, J., Xapelli, S., Ferreira, R., Kristiansen, H., Woldbye, David Paul Drucker, Oliveira, C. R. & Malva, J. O., 2007, In: The FASEB Journal. 21, 3, p. 671-681 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid activation of the extracellular signal-regulated kinase 1/2 (ERK1/2) signaling pathway by electroconvulsive shock in the rat prefrontal cortex is not associated with TrkB neurotrophin receptor activation
Hansen, H. H., Rantamaki, T. P. J., Larsen, M. H., Woldbye, David Paul Drucker, Mikkelsen, J. D. & Castren, E. H., 2007, In: Cellular and Molecular Neurobiology. 27, 5, p. 585-594 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Aripiprazole blocks acute self-administration of cocaine and is not self-administered in mice
Sørensen, G., Sager, T. N., Petersen, Jørgen Holm, Brennum, L. T., Thøgersen, P., Hee Bengtsen, C., Thomsen, M., Wörtwein, Gitta, Fink-Jensen, Anders & Woldbye, David Paul Drucker, 2008, In: Psychopharmacology. 199, 1, p. 37-46 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of acute and chronic aripiprazole treatment on choice between cocaine self-administration and food under a concurrent schedule of reinforcement in rats
Thomsen, M., Fink-Jensen, Anders, Woldbye, David Paul Drucker, Wörtwein, Gitta, Sager, T., Holm, R., Pepe, L. & Barak Caine, S., 2008, In: Psychopharmacology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuropeptide y promotes neurogenesis in murine subventricular zone
Agasse, F., Bernardino, L., Kristiansen, H., Christiansen, S. H., Ferreira, R., Silva, B., Grade, S., Woldbye, David Paul Drucker, Malva, J. O. & Kristiansen, H., 2008, In: Stem Cells. 26, 6, p. 1636-45 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
An intron 1 polymorphism in the cholecystokinin-A receptor gene associated with schizophrenia in males
Koefoed, P., Hansen, T. V. O., Woldbye, D. P. D., Werge, T., Mors, O., Hansen, T., Jakobsen, K. D., Nordentoft, M., Wang, A., Bolwig, T. G., Rehfeld, J. F., Koefoed, P., Hansen, T. V. O., Woldbye, D. P. D., Werge, T., Mors, O., Hansen, T. F., Jakobsen, K. D., Nordentoft, M., Wang, A. & 2 others, , 2009, In: Acta Psychiatrica Scandinavica. 120, 4, p. 281-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complex plastic changes in the neuropeptide Y system during ethanol intoxication and withdrawal in the rat brain
Olling, J. D., Ulrichsen, J., Christensen, D. Z., Woldbye, David Paul Drucker, Olling, J. D., Ulrichsen, J., Christensen, D. Z. & Woldbye, D. P. D., 2009, In: Journal of Neuroscience Research. 87, 10, p. 2386-97 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo characterization of high Basal signaling from the ghrelin receptor
Petersen, P. S., Woldbye, David Paul Drucker, Madsen, A. N., Egerod, Kristoffer Lihme, Jin, C., Lang, M., Rasmussen, M., Beck-Sickinger, A. G. & Holst, Birgitte, 2009, In: Endocrinology. 150, 11, p. 4920-30 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuropeptide Y infusion into the shell region of the rat nucleus accumbens increases extracellular levels of dopamine
Sørensen, G., Wegener, G., Hasselstrøm, J., Hansen, T. V. O., Wörtwein, Gitta, Fink-Jensen, Anders & Woldbye, David Paul Drucker, 2009, In: NeuroReport. 20, 11, p. 1023-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Increased amphetamine-induced locomotor activity, sensitization, and accumbal dopamine release in M5 muscarinic receptor knockout mice
Schmidt, L. S., Miller, A. D., Lester, D. B., Bay-Richter, C., Schülein, C., Frikke-Schmidt, H., Wess, J., Blaha, C. D., Woldbye, David Paul Drucker, Fink-Jensen, Anders & Wörtwein, Gitta, 2010, In: Psychopharmacology. 207, 4, p. 547-58 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A subpopulation of neuronal M4 muscarinic acetylcholine receptors plays a critical role in modulating dopamine-dependent behaviors
Jeon, J., Dencker, D., Wörtwein, G., Woldbye, D. P. D., Cui, Y., Davis, A. A., Levey, A. I., Schütz, G., Sager, T. N., Mørk, A., Li, C., Deng, C-X., Fink-Jensen, A., Wess, J., Jeon, J., Nielsen, D. D., Wörtwein, G., Woldbye, D. P. D., Cui, Y., Davis, A. A. & 8 others, , 10 Feb 2010, In: Journal of Neuroscience. 30, 6, p. 2396-405 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene expression in the neuropeptide Y system during ethanol withdrawal kindling in rats
Olling, J. D., Ulrichsen, J., Correll, M., Woldbye, David Paul Drucker, Olling, J. D., Ulrichsen, J., Correll, M. & Woldbye, D. P. D., 1 Mar 2010, In: Alcoholism: Clinical and Experimental Research. 34, 3, p. 462-70 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene variations in the cholecystokinin system in patients with panic disorder
Koefoed, P., Woldbye, David Paul Drucker, Hansen, T. O., Hansen, E. S., Knudsen, Gitte Moos, Bolwig, T. G., Rehfeld, Jens Frederik, Kofoed, P., Woldbye, D. P. D., Hansen, T. O., Hansen, E., Knudsen, G. M., Bolwig, T. G. & Rehfeld, J. F., 1 Apr 2010, In: Psychiatric Genetics. 20, 2, p. 59-64 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adeno-associated viral vector-induced overexpression of neuropeptide Y Y2 receptors in the hippocampus suppresses seizures
Woldbye, David Paul Drucker, Ängehagen, M., Gøtzsche, C. R., Elbrønd-Bek, H., Sørensen, Andreas Toft, Christiansen, S. H. O., Olesen, M. V., Nikitidou, L., Hansen, T. V. O., Kanter-Schlifke, I. & Kokaia, M., Sep 2010, In: Brain. 133, 9, p. 2778-88 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of the galanin system by repeated electroconvulsive seizures in mice
Christiansen, S. H. & Woldbye, David Paul Drucker, 1 Dec 2010, In: Journal of Neuroscience Research. 88, 16, p. 3635-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Increased cocaine self-administration in M4 muscarinic acetylcholine receptor knockout mice.
Schmidt, L. S., Thomsen, M., Weikop, Pia, Nielsen, D. D., Wess, J., Woldbye, David Paul Drucker, Wörtwein, Gitta & Fink-Jensen, Anders, 2011, In: Psychopharmacology. 216, 3, p. 367-378 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Involvement of a subpopulation of neuronal M4 muscarinic acetylcholine receptors in the antipsychotic-like effects of the M1/M4 preferring muscarinic receptor agonist xanomeline
Dencker, D., Wörtwein, Gitta, Weikop, Pia, Jeon, J., Thomsen, M., Sager, T. N., Mørk, A., Woldbye, David Paul Drucker, Wess, J. & Fink-Jensen, Anders, 2011, In: Journal of Neuroscience. 31, 16, p. 5905-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fluoxetine reverts chronic restraint stress-induced depression-like behaviour and increases neuropeptide Y and galanin expression in mice
Christiansen, S. H. O., Olesen, M. V., Wörtwein, Gitta & Woldbye, David Paul Drucker, 20 Jan 2011, In: Behavioural Brain Research. 216, 2, p. 585-91 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antipsychotic-induced catalepsy is attenuated in mice lacking the M4 muscarinic acetylcholine receptor.
Fink-Jensen, Anders, Schmidt, L. S., Dencker, D., Schülein, C., Wess, J., Wörtwein, Gitta & Woldbye, David Paul Drucker, 10 Apr 2011, In: European Journal of Pharmacology. 656, 1-3, p. 39-44 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The norepinephrine transporter gene is a candidate gene for panic disorder
Buttenschøn, H. N., Kristensen, A. S., Buch, H. N., Andersen, J. H., Bonde, Jens Peter, Grynderup, M. B., Hansen, Åse Marie, Kolstad, H., Kaergaard, A., Kaerlev, L., Mikkelsen, S., Thomsen, Jane Frølund, Koefoed, P., Erhardt, A., Woldbye, David Paul Drucker, Børglum, A. & Mors, O., 1 Jun 2011, In: Journal of Neural Transmission. 118, 6, p. 969-76 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
A genome-wide study of panic disorder suggests the amiloride-sensitive cation channel 1 as a candidate gene
Gregersen, N., Dahl, H. A., Buttenschøn, H. N., Nyegaard, M., Hedemand, A., Als, T. D., Wang, August Gabriel, Joensen, S., Woldbye, David Paul Drucker, Koefoed, P., Kristensen, A. S., Kruse, T. A., Børglum, A. & Mors, O., 2012, In: European Journal of Human Genetics. 20, p. 84-90 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An allosteric enhancer of M4 muscarinic acetylcholine receptor function inhibits behavioral and neurochemical effects of cocaine
Nielsen, D. D., Weikop, Pia, Sørensen, G., Woldbye, David Paul Drucker, Wörtwein, Gitta, Wess, J. & Fink-Jensen, Anders, 2012, In: Psychopharmacology. 224, 2, p. 277-87 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combined gene overexpression of neuropeptide Y and its receptor Y5 in the hippocampus suppresses seizures.
Gøtzsche, C. R., Nikitidou, L., Sørensen, Andreas Toft, Olesen, M. V., Sørensen, G., Christiansen, S. H. O., Ängehagen, M., Woldbye, David Paul Drucker & Kokaia, M., 2012, In: Neurobiology of Disease. 45, p. 288-96 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epigenetic regulation of Arc and c-Fos in the hippocampus after acute electroconvulsive stimulation in the rat.
Dyrvig, M., Hansen, H. H., Christiansen, S. H. O., Woldbye, David Paul Drucker, Mikkelsen, Jens D. & Lichota, J., 2012, In: Brain Research Bulletin. 88, p. 507-13 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Methamphetamine-induced changes in the mice hippocampal neuropeptide Y system: implications for memory impairment.
Gonçalves, J., Baptista, S., Olesen, M., Malva, J., Woldbye, David Paul Drucker & Silva, A., 2012, In: Journal of Neurochemistry. 123, 6, p. 1041-53 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mice lacking neuropeptide Y show increased sensitivity to cocaine
Sørensen, G. & Woldbye, David Paul Drucker, 2012, In: Synapse. 66, p. 840-3 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Replication and meta-analysis of TMEM132D gene variants in panic disorder.
Erhardt, A., Akula, N., Schumacher, J., Czamara, D., Karabalai, N., Müller-Myhsok, B., Mors, O., Borglum, A., Kristensen, AS., Woldbye, D. P. D., Koefoed, P., Eriksson, E., Maron, E., Metspalu, A., Nurnberger, J., Philibert, RA., Kennedy, J., Domschke, K., Reif, A., Deckert, J. & 10 others, , 2012, In: Translational Psychiatry. 2:e156Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Y5 neuropeptide Y receptor overexpression in mice neither affects anxiety- and depression-like behaviours nor seizures but confers moderate hyperactivity.
Olesen, M. V., Christiansen, S. H. O., Gøtzsche, C. R., Holst, Birgitte, Kokaia, M. & Woldbye, David Paul Drucker, 2012, In: Neuropeptides (Sheffield). 46, 2, p. 71-9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuropeptide Y Y1 receptor hippocampal overexpression via viral vectors is associated with modest anxiolytic-like and proconvulsant effects in mice.
Olesen, M. V., Christiansen, S. H. O., Gøtzsche, C. R., Nikitidou, L., Kokaia, M. & Woldbye, David Paul Drucker, Feb 2012, In: Journal of Neuroscience Research. 90, 2, p. 498-507 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuropeptide Y Y5 receptor antagonism attenuates cocaine-induced effects in mice.
Sørensen, G., Jensen, M., Weikop, Pia, Nielsen, D. D., Christiansen, S. H. O., Loland, Claus Juul, Bengtsen, C. H., Petersen, Jørgen Holm, Fink-Jensen, Anders, Wörtwein, Gitta & Woldbye, David Paul Drucker, Feb 2012, In: Psychopharmacology. 222, p. 565-577 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
Koefoed, P., Woldbye, D. P. D., Hansen, T. V. O., Eplov, L. F., Christiansen, S. H. O., Mors, O., Kessing, L. V., Werge, T., Kaipio, K., Pesonen, U., Fahmy, T., Mellerup, E. T., Jakobsen, K. D., Hansen, E. S., Knudsen, G. M., Bukh, J. D., Bock, C., Lindberg, C., Kristensen, A. S., Dam, H. & 6 others, , 23 Mar 2012, In: Acta Neuropsychiatrica. 24, 2, p. 81-90 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
A C-terminal PDZ domain-binding sequence is required for striatal distribution of the dopamine transporter
Rickhag, Karl Mattias, Herborg, Freja, Sørensen, G., Strandfelt, K. N., Andresen, B., Gotfryd, K., Madsen, Kenneth Lindegaard, Vestergaard-Klewe, I., Ammendrup-Johnsen, I., Eriksen, J., Newman, A. H., Füchtbauer, E., Gomeza, J., Woldbye, David Paul Drucker, Wörtwein, Gitta & Gether, Ulrik, 2013, In: Nature Communications. 4, p. 1-13 13 p., 1580.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Peptide Antagonist of ErbB Receptors, Inherbin3, Induces Neurite Outgrowth from Rat Cerebellar Granule Neurons Through ErbB1 Inhibition
Xu, R., Pankratova, Stanislava, Christiansen, S. H. O., Woldbye, David Paul Drucker, Højland, A., Bock, E. M. & Berezin, V., 2013, In: Neurochemical Research. 38, 12, p. 2550-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Electroconvulsive stimulation reverses anhedonia and cognitive impairments in rats exposed to chronic mild stress.
K, H., Woldbye, David Paul Drucker & Wiborg, O., 2013, In: European Neuropsychopharmacology. 23, 12, p. 1789-94 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Membrane permeable C-terminal dopamine transporter peptides attenuate amphetamine-evoked dopamine release.
Rickhag, Karl Mattias, Owens, W., Winkler, M., Strandfelt, K. N., Rathje, Mette, Sørensen, G., Andresen, B., Madsen, Kenneth Lindegaard, Nygaard Jørgensen, T., Wörtwein, Gitta, Woldbye, David Paul Drucker, Sitte, H. H., Daws, L. C. & Gether, Ulrik, 2013, In: Journal of Biological Chemistry. 288, p. 27534-44 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The neuropeptide galanin promotes neuronal differentiation in murine subventricular zone cultures
Agasse, F., Christiansen, S. H. O., Malva, J. & Woldbye, David Paul Drucker, 2013, In: Stem Cells and Development. 22, 11, p. 1693-1708 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuropeptide Y Y5 receptor antagonism causes faster extinction and attenuates reinstatement in cocaine-induced place preference
Sørensen, G., Wörtwein, Gitta, Fink-Jensen, Anders & Woldbye, David Paul Drucker, Apr 2013, In: Pharmacology, Biochemistry and Behavior. 105, p. 151-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PICK1 deficiency impairs secretory vesicle biogenesis and leads to growth retardation and decreased glucose tolerance
Holst, Birgitte, Madsen, Kenneth Lindegaard, Jansen, A. M., Jin, C., Rickhag, Karl Mattias, Lund, Viktor Karlovich, Jensen, M., Bhatia, V., Sørensen, G., Madsen, A. N., Xue, Z., Møller, S. K., Woldbye, David Paul Drucker, Qvortrup, Klaus, Huganir, R., Stamou, Dimitrios, Kjærulff, Ole & Gether, Ulrik, Apr 2013, In: P L o S Biology (Online). 11, 4, p. 1-25 25 p., e1001542.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuropeptide Y genes and suicidal behaviour among schizophrenic patients
Wang, August Gabriel, Koefoed, P., Jacoby, A. S., Woldbye, David Paul Drucker, Rasmussen, Henrik Berg, Timm, S., Dam, H., Jakobsen, K. D., Nordentoft, Merete, Jürgens, Gesche, Sorensen, H. J., Garsdal, O., Hvid, M. & Werge, Thomas, Jun 2013, In: Psychiatric Genetics. 23, 3, p. 139-40 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Are TMEM genes potential candidate genes for panic disorder?
NO, G., Buttenschøn, H. N., Hedemand, A., Dahl, H. A., Kristensen, A. S., B, C., Woldbye, David Paul Drucker, Koefoed, P., Erhardt, A., Kruse, T. A., Wang, August Gabriel, Børglum, A. & Mors, O., 2014, In: Psychiatric Genetics. 24, 1, p. 37-41 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Temporal gene expression profile after acute electroconvulsive stimulation in the rat.
Dyrvig, M., Christiansen, S. H. O., Woldbye, David Paul Drucker & Lichota, J., 2014, In: Gene. 539, 1, p. 8-14 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Addiction-Related Effects of DOV 216,303 and Cocaine: A Comparative Study in the Mouse
Sørensen, G., Husum, H., Brennum, L. T., Bundgaard, C., Montezinho, L. C. P., Mørk, A., Wörtwein, Gitta & Woldbye, David Paul Drucker, Jun 2014, In: Basic & Clinical Pharmacology & Toxicology. 114, 6, p. 451-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuropeptide Y-stimulated [(35) S]GTPγs functional binding is reduced in the hippocampus after kainate-induced seizures in mice
Elbrønd-Bek, H., Olling, J. D., Gøtzsche, C. R., Waterfield, A., Wörtwein, Gitta & Woldbye, David Paul Drucker, 9 Jul 2014, In: Synapse. 68, 10, p. 427-36 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anxiolytic-like effects after vector-mediated overexpression of neuropeptide Y in the amygdala and hippocampus of mice
Christiansen, S. H. O., Olesen, M. V., Gøtzsche, C. R. & Woldbye, David Paul Drucker, 16 Sep 2014, In: Neuropeptides. 48, 6, p. 335-44 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Activation of Neuropeptide Y Receptors Modulates Retinal Ganglion Cell Physiology and Exerts Neuroprotective Actions In Vitro
Martins, J., Elvas, F., Brudzewsky, D., Martins, T., Kolomiets, B., Tralhão, P., Gøtzsche, C. R., Cavadas, C., Castelo-Branco, M., Woldbye, David Paul Drucker, Picaud, S., Santiago, A. R. & Ambrósio, A. F., 2015, In: A S N Neuro. 7, 4, p. 1-21 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Visualization of Functional Neuropeptide Y Receptors in the Mouse Hippocampus and Neocortex Using [35S]GTPγS Binding
Elbrønd-Bek, H., Gøtzsche, C. R., Skinbjerg, M., Christensen, D. Z., Plenge, P. K. & Woldbye, David Paul Drucker, 2015, In: International Journal of Peptide Research and Therapeutics. 21, 3, p. 269-278 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Epigenetic regulation of Dnmt3a and Arc gene expression after electroconvulsive stimulation in the rat
Dyrvig, M., Gotzsche, C. R., Woldbye, David Paul Drucker & Lichota, J., Jul 2015, In: Molecular and Cellular Neuroscience. 67, p. 137-143 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential Effect of Neuropeptides on Excitatory Synaptic Transmission in Human Epileptic Hippocampus
Ledri, M., Sørensen, Andreas Toft, Madsen, M. G., Christiansen, S. H., Ledri, L. N., Cifra, A., Bengzon, J., Lindberg, E., Pinborg, L. H., Jespersen, B., Gotzsche, C. R., Woldbye, David Paul Drucker, Andersson, M. & Kokaia, M., 1 Jul 2015, In: Journal of Neuroscience. 35, 26, p. 9622-9631 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Optogenetik bringer neurale mekanismer frem i lyset og kan blive en ny terapiform
Axelsen, T. M., Navntoft, C. A. E., Christiansen, S. H., Dreyer, J. K., Sørensen, Jakob Balslev, Gether, Ulrik & Woldbye, David Paul Drucker, 17 Aug 2015, In: Ugeskrift for Laeger. 177, 34, p. 2-5 4 p., V06150501.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Candidate genes in panic disorder: meta-analyses of 23 common variants in major anxiogenic pathways
Howe, A. S., Buttenschön, H. N., Bani-Fatemi, A., Maron, E., Otowa, T., Erhardt, A., Binder, E. B., Gregersen, N. O., Mors, O., Woldbye, D. P., Domschke, K., Reif, A., Shlik, J., Kks, S., Kawamura, Y., Miyashita, A., Kuwano, R., Tokunaga, K., Tanii, H., Smoller, J. W. & 3 others, , 2016, In: Molecular Psychiatry. 21, 5, p. 665-679 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Decreased spontaneous activity in AMPK alpha 2 muscle specific kinase dead mice is not caused by changes in brain dopamine metabolism
Møller, Lisbeth L V, Sylow, Lykke, Gøtzsche, C. R., Serup, A. K. L., Christiansen, S. H., Weikop, Pia, Kiens, Bente, Woldbye, David Paul Drucker & Richter, Erik A., 2016, In: Physiology & Behavior. 164, Part A, p. 300-305 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Translational approach for gene therapy in epilepsy: Model system and unilateral overexpression of neuropeptide Y and Y2 receptors
Ledri, L. N., Melin, E., Christiansen, S. H., Gøtzsche, C. R., Cifra, A., Woldbye, David Paul Drucker & Kokaia, M., Feb 2016, In: Neurobiology of Disease. 86, p. 52-61 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of NPY in learning and memory
Gøtzsche, C. R. & Woldbye, David Paul Drucker, 1 Feb 2016, In: Neuropeptides. 55, p. 79-89 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Optogenetic control of human neurons in organotypic brain cultures
Andersson, M., Avaliani, N., Svensson, A., Wickham, J., Pinborg, Lars Hageman, Jespersen, B., Christiansen, S. H., Bengzon, J., Woldbye, David Paul Drucker & Kokaia, M., 21 Apr 2016, In: Scientific Reports. 6, 5 p., 24818.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anxiolytic-Like Effects of Increased Ghrelin Receptor Signaling in the Amygdala
Jensen, M., Ratner, C., Rudenko, Olga, Christiansen, S. H., Skov, Louise Julie, Johnsen, Cecilie Hundahl, Woldbye, David Paul Drucker & Holst, Birgitte, 1 May 2016, In: International Journal of Neuropsychopharmacology. 19, 5, 12 p., pyv123.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Can gene therapy treat anxiety? Overexpression of Neuropeptide S using adeno-associated viral vectors
Tillmann, S., Elbrond-Bek, H., Gotzsche, C. R., Christiansen, S. H., Mathe, A. A., Woldbye, David Paul Drucker & Wegener, G., Jun 2016, In: International Journal of Neuropsychopharmacology. 19, S1, p. 52-53Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
DREADDs suppress seizure-like activity in a mouse model of pharmacoresistant epileptic brain tissue
Avaliani, N., Andersson, M., Thomsen, A. H. R., Woldbye, David Paul Drucker & Kokaia, M., Oct 2016, In: Gene Therapy. 23, 10, p. 760-766 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association between genes on chromosome 19p13.2 and panic disorder
Gregersen, N. O., Buttenschon, H. N., Hedemand, A., Nielsen, M. N., Dahl, H. A., Kristensen, A. S., Johansen, O., Woldbye, David Paul Drucker, Erhardt, A., Krusee, T. A., Wang, August Gabriel, Borglum, A. D. & Mors, O., Dec 2016, In: Psychiatric Genetics. 26, 6, p. 287-292Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MicroRNA 101b Is Downregulated in the Prefrontal Cortex of a Genetic Model of Depression and Targets the Glutamate Transporter SLC1A1 (EAAT3) in Vitro
Bin Wei, Y., Melas, P. A., Villaescusa, J. C., Liu, J. J., Xu, N., Christiansen, S. H., Elbrønd-Bek, H., Woldbye, David Paul Drucker, Wegener, G., Mathe, A. A. & Lavebratt, C., Dec 2016, In: International Journal of Neuropsychopharmacology. 19, 12, 9 p., pyw069.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Effects of amphetamine and methylphenidate on attentional performance and impulsivity in the mouse 5-Choice Serial Reaction Time Task
Caballero Puntiverio, M., Fitzpatrick, C. M., Woldbye, David Paul Drucker & Andreasen T., Jesper, 2017, In: Journal of Psychopharmacology. 31, 2, p. 272-283Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GENOME-WIDE ASSOCIATION STUDY OF PANIC DISORDER
Forstner, A. J., Wolf, C., Maron, E., Erhardt, A., Eriksson, E., Hovatta, L., Lavebratt, C., Allgulander, C., Woldbye, David Paul Drucker, Mors, O., Mueller-Myhsok, B., Binder, E. B., Rueck, C., Deckert, J. & Schumacher, J., 2017, In: European Neuropsychopharmacology. 27, S2, p. S217-S218Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Theory of Visual Attention (TVA) applied to mice in the 5-choice serial reaction time task
Fitzpatrick, C. M., Caballero-Puntiverio, M., Gether, Ulrik, Habekost, Thomas, Bundesen, C., Vangkilde, Signe, Woldbye, David Paul Drucker, Andreasen T., Jesper & Petersen, Anders, 2017, In: Psychopharmacology. 234, 5, p. 845-855Research output: Contribution to journal › Journal article › Research › peer-review
ID: 9451
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
Research output: Contribution to journal › Journal article › Research › peer-review
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PICK1 deficiency impairs secretory vesicle biogenesis and leads to growth retardation and decreased glucose tolerance
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Locomotor- and Reward-Enhancing Effects of Cocaine Are Differentially Regulated by Chemogenetic Stimulation of Gi-Signaling in Dopaminergic Neurons
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