Birthe Brandt Kragelund

Birthe Brandt Kragelund

Professor


  1. Published

    (S)Pinning down protein interactions by NMR

    Teilum, Kaare, Kunze, M. B. A., qrc243, qrc243 & Kragelund, Birthe Brandt, Mar 2017, In: Protein Science. 26, 3, p. 436-451 16 p.

    Research output: Contribution to journalReviewResearchpeer-review

  2. Published

    1H, 13C, and 15N assignments of un-myristoylated Ca2+-frequenin, a synaptic efficacy modulator

    Kragelund, Birthe Brandt, Hauenschild, A., Carlström, G., Pongs, O. & Finn, B. E., Jan 2000, In: Journal of Biomolecular N M R. 16, 1, p. 85-6 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A Far UV CD study of de novo designed antimicrobial coiled coils upon interaction with model membranes

    Søndergaard, S. L., Kragelund, Birthe Brandt, Thulstrup, Peter Waaben, Brahm, Jesper, Siegumfeldt, Henrik, Frimodt-Møller, N. & Hansen, Paul Robert, 2010, In: Journal of Peptide Science. S2

    Research output: Contribution to journalConference abstract in journalResearch

  4. Published

    A combined computational and structural model of the full-length human prolactin receptor

    Bugge, K. Ø., Papaleo, E., Haxholm, G. W., Hopper, J. T. S., Robinson, C. V., Olsen, Johan Gotthardt, Lindorff-Larsen, Kresten & Kragelund, Birthe Brandt, 2016, In: Nature Communications. 7, 11 p., 11578.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A context-dependent and disordered ubiquitin-binding motif

    Dreier, Jesper Elmsted, Prestel, Andreas, Martins, J. M., Brøndum, S. S., Nielsen, Olaf, Garbers, Anna Engstrøm, Suga, H., Boomsma, Wouter, Rogers, Joseph Matthew, Hartmann-Petersen, Rasmus & Kragelund, Birthe Brandt, 2022, In: Cellular and molecular life sciences : CMLS. 79, 9, 21 p., 484.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A de novo designed monomeric, compact three helix bundle protein on a carbohydrate template

    Malik, L., Nygård, Jesper, Christensen, Niels Johan, Madsen, C. S., Rösner, Heike Ilona, Kragelund, Birthe Brandt, Høiberg-Nielsen, R., Streicher, W., Arleth, Lise, Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2015, In: ChemBioChem. 16, 13, p. 1905-1918 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A disordered acidic domain in GPIHBP1 harboring a sulfated tyrosine regulates lipoprotein lipase

    Kristensen, Kristian Kølby, Midtgaard, S. R., Mysling, S., Kovrov, O., Hansen, L. B., Skar-Gislinge, Nicholas, Beigneux, A. P., Kragelund, Birthe Brandt, Olivecrona, G., Young, S. G., Jørgensen, T. J. D., Fong, L. G. & Ploug, Michael, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 26, p. E6020-E6029 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    A glutamine-based single α-helix scaffold to target globular proteins

    Escobedo, A., Piccirillo, J., Aranda, J., Diercks, T., Mateos, B., Garcia-Cabau, C., Sanchez-Navarro, M., Topal, B., Biesaga, M., Staby, L., Kragelund, Birthe Brandt, Garcia, J., Millet, O., Orozco, M., Coles, M., Crehuet, R. & Salvatella, X., 2022, In: Nature Communications. 13, 18 p., 7073.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    A growth hormone receptor SNP promotes lung cancer by impairment of SOCS2-mediated degradation

    Chhabra, Y., Wong, H. Y., Nikolajsen, L. F., Steinocher, H., Papadopulos, A., Tunny, K. A., Meunier, F. A., Smith, A. G., Kragelund, Birthe Brandt, Brooks, A. J. & Waters, M. J., 2018, In: Oncogene. 37, p. 489-501 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    A highly compliant protein native state with a spontaneous-like mechanical unfolding pathway

    Heiðarsson, P. O., Valpapuram, I., Camilloni, C., Imparato, A., Tiana, G., Poulsen, F. M., Kragelund, Birthe Brandt & Cecconi, C., 2012, In: Journal of the American Chemical Society. 134, 41, p. 17068-17075 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A loop of coagulation factor VIIa influencing macromolecular substrate specificity.

    Bjelke, J. R., Persson, E., Rasmussen, H. B., Kragelund, Birthe Brandt & Olsen, O. H., 2006, In: FEBS Letters. 581, 1, p. 71-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    A phosphorylation-motif for tuneable helix stabilisation in intrinsically disordered proteins - Lessons from the sodium proton exchanger 1 (NHE1)

    Hendus-Altenburger, R., Lambrughi, M., Terkelsen, Thilde Bagger, Pedersen, Stine Helene Falsig, Papaleo, E., Lindorff-Larsen, Kresten & Kragelund, Birthe Brandt, Sep 2017, In: Cellular Signalling. 37, p. 40-51 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    A residue quartet in the extracellular domain of the prolactin receptor selectively controls mitogen-activated protein kinase signaling

    Zhang, C., Nygaard, M., Haxholm, G. W., Boutillon, F., Bernadet, M., Hoos, S., England, P., Broutin, I., Kragelund, Birthe Brandt & Goffin, V., 2015, In: Journal of Biological Chemistry. 290, 19, p. 11890-11904 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    A two-step protein quality control pathway for a misfolded DJ-1 variant in fission yeast

    Mathiassen, S. G., Larsen, I. B., Poulsen, E. G., Madsen, C. T., Papaleo, E., Lindorff-Larsen, Kresten, Kragelund, Birthe Brandt, Nielsen, Michael Lund, Kriegenburg, F. & Hartmann-Petersen, Rasmus, 2015, In: The Journal of Biological Chemistry. 290, 34, p. 21141-21153 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Acyl-CoA binding proteins; structural and functional conservation over 2000 MYA.

    Faergeman, N. J., Wadum, M., Feddersen, S., Burton, M., Kragelund, Birthe Brandt & Knudsen, J., 2007, In: Molecular and Cellular Biochemistry. 299, 1-2, p. 55-65 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Acyl-CoA-binding protein (ACBP) localizes to the endoplasmic reticulum and Golgi in a ligand-dependent manner in mammalian cells.

    Hansen, J. S., Færgeman, N. J., Kragelund, Birthe Brandt & Knudsen, J., 2008, In: Biochemical Journal. 410, 3, p. 463-472 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Acyl-coenzyme A binding protein (ACBP)

    Kragelund, Birthe Brandt, Knudsen, J. & Poulsen, F. M., 23 Nov 1999, In: B B A - Reviews on Cancer. 1441, 2-3, p. 150-61 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Alginate Trisaccharide Binding Sites on the Surface of β-Lactoglobulin Identified by NMR Spectroscopy: Implications for Molecular Network Formation

    Stender, E. G. P., Birch, J., Kjeldsen, C., Nielsen, L. D., Duus, J. Ø., Kragelund, Birthe Brandt & Svensson, B., 2019, In: ACS Omega. 4, 4, p. 6165-6174 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    An efficient arabinoxylan-debranching α-L-arabinofuranosidase of family GH62 from Aspergillus nidulans contains a secondary carbohydrate binding site

    Wilkens, C., Andersen, S., Petersen, B. O., Li, A., Busse-Wicher, M., Birch, J., Cockburn, D., Nakai, H., Christensen, H. E. M., Kragelund, Birthe Brandt, Dupree, P., McCleary, B., Hindsgaul, O., Abou Hachem, M. & Svensson, B., 2016, In: Applied Microbiology and Biotechnology. 100, 14, p. 6265-6277 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    An efficient method for estimating the hydrodynamic radius of disordered protein conformations

    Nygaard, M., Kragelund, Birthe Brandt, Papaleo, E. & Lindorff-Larsen, Kresten, 8 Aug 2017, In: Biophysical Journal. 113, 3, p. 550-557 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Analyzing temperature-induced transitions in disordered proteins by NMR spectroscopy and secondary chemical shift analyses

    Kjærgaard, M., Poulsen, F. M. & Kragelund, Birthe Brandt, 2012, Intrinsically disordered protein analysis: methods and experimental tools. Uversky, V. N. & Dunker, A. K. (eds.). Springer, Vol. 2. p. 249-256 8 p. (Methods in Molecular Biology, Vol. 896).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  22. Published

    Application of Hydrogen Exchange Kinetics to Studies of Protein Folding

    Teilum, Kaare, Kragelund, Birthe Brandt & Poulsen, F. M., 2005, Protein Folding Handbook. Buchner, J. & Kiefhaber, T. (eds.). Weinheim: Wiley-VCH, p. 634-672

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  23. Published

    Assessment of models for calculating the hydrodynamic radius of intrinsically disordered proteins

    Pesce, Francesco, Newcombe, Estella Anne, Seiffert, P., Tranchant, E. E., Olsen, Johan Gotthardt, Grace, C. R., Kragelund, Birthe Brandt & Lindorff-Larsen, Kresten, 2023, In: Biophysical Journal. 122, 2, p. 310-321 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Avidity within the N-terminal anchor drives α-synuclein membrane interaction and insertion

    Cholak, E., Bugge, K., Khondker, A., Gauger, K., Pedraz-Cuesta, E., Pedersen, M. E., Bucciarelli, S., Vestergaard, Bente, Pedersen, Stine Helene Falsig, Rheinstädter, M. C., Langkilde, Annette Eva & Kragelund, Birthe Brandt, 2020, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34, 6, p. 7462-7482 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Behaviour of intrinsically disordered proteins in protein-protein complexes with an emphasis on fuzziness

    Olsen, Johan Gotthardt, Teilum, Kaare & Kragelund, Birthe Brandt, Sep 2017, In: Cellular and Molecular Life Sciences. 74, 17, p. 3175-3183 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Binding Sites for Oligosaccharide Repeats from Lactic Acid Bacteria Exopolysaccharides on Bovine β-Lactoglobulin Identified by NMR Spectroscopy

    Birch, J., Khan, S., Madsen, M., Kjeldsen, C., Møller, M. S., Stender, E. G. P., Peters, G. H. J., Duus, J. Ø., Kragelund, Birthe Brandt & Svensson, B., 2021, In: ACS Omega. 6, 13, p. 9039-9052 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Binding site structure of one LRP-RAP complex: implications for a common ligand-receptor binding motif.

    Jensen, G. A., Andersen, O. M., Bonvin, A. M. J. J., Bjerrum-Bohr, I., Etzerodt, M., Thøgersen, H. C., O'Shea, Charlotte, Poulsen, F. M. & Kragelund, Birthe Brandt, 2006, In: Journal of Molecular Biology. 362, 4, p. 700-16 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    CECAM workshop on intrinsically disordered proteins

    Rösner, Heike Ilona, Papaleo, E., Haxholm, G. W., Best, R. B., Kragelund, Birthe Brandt & Lindorff-Larsen, Kresten, 2014, In: Intrinsically Disordered Proteins. 2, 1, p. 1-5 5 p.

    Research output: Contribution to journalConference abstract in journalResearch

  29. Published

    Characterization of Dynamic IDP Complexes by NMR Spectroscopy

    Prestel, Andreas, Bugge, K., Staby, L., Hendus-Altenburger, R. & Kragelund, Birthe Brandt, 2018, Intrinsically Disordered Proteins. Rhoades, E. (ed.). Academic Press, p. 193-226 34 p. (Methods in Enzymology, Vol. 611).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  30. Published

    Checkpoint activation by Spd1: a competition-based system relying on tandem disordered PCNA binding motifs

    Olsen, Johan Gotthardt, Prestel, Andreas, Kassem, N., Broendum, S. S., Hossain, Mohammad Shamim, Simonsen, Signe, Grysbæk, M., Mortensen, J., Rytkjær, L. L., Haxholm, G. W., Marabini, R., Holmberg, Christian, Carr, A. M., Crehuet, R., Nielsen, Olaf & Kragelund, Birthe Brandt, 2024, In: Nucleic acids symposium series. 52, 4, p. 2030–2044 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Choreography by Structural Disorder in Membrane Proteins

    Kragelund, Birthe Brandt, 2017, In: Biophysical Society. Annual Meeting. Abstracts. 112, 3, suppl. 1, p. 12A 1 p., 65-Subg.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  32. Published

    Class I Cytokine Receptors: Towards the Inside

    Steinocher, H., Bugge, K. Ø., Nikolajsen, L. F., Lindorff-Larsen, Kresten, Brooks, A. & Kragelund, Birthe Brandt, 2017, In: Biophysical Society. Annual Meeting. Abstracts. 112, 3. Suppl. 1, p. 171A 1 p., 845-Plat.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  33. Published

    Cold denaturation of the HIV-1 protease monomer

    Rösner, Heike Ilona, Caldarini, M., Prestel, Andreas, Vanoni, M. A., Broglia, R. A., Aliverti, A., Tiana, G. & Kragelund, Birthe Brandt, 7 Feb 2017, In: Biochemistry. 56, 8, p. 1029-1032 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Comment on “Intrinsic protein disorder uncouples affinity from binding specificity

    Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2023, In: Protein Science. 32, 4, 2 p., e4602.

    Research output: Contribution to journalComment/debateResearchpeer-review

  35. Published

    Conformational entropy in molecular recognition of intrinsically disordered proteins

    Skriver, Karen, Theisen, Frederik Friis & Kragelund, Birthe Brandt, 2023, In: Current Opinion in Structural Biology. 83, 8 p., 102697.

    Research output: Contribution to journalReviewResearchpeer-review

  36. Published

    Connecting the αα-hubs: same fold, disordered ligands, new functions

    Staby, L., Bugge, K., Falbe-Hansen, R. G., Salladini, Edoardo, Skriver, Karen & Kragelund, Birthe Brandt, 2021, In: Cell Communication and Signaling. 19, 5 p., 2.

    Research output: Contribution to journalLetterResearchpeer-review

  37. Published

    Context Matters in Disorder Based Protein Communication

    Kragelund, Birthe Brandt, Prestel, Andreas, Wickmann, N., Martins, J., Boomsma, Wouter, Staby, L., Hendus-Altenburger, R. & Skriver, Karen, 2020, In: Biophysical Journal. 118, 3, suppl. 1, p. 491A 2407-Plat.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  38. Published

    Crystal structure of an affinity-matured prolactin complexed to its dimerized receptor reveals the topology of hormone binding site 2.

    Broutin, I., Jomain, J., Tallet, E., Van Agthoven, J., Raynal, B., Hoos, S., Kragelund, Birthe Brandt, Kelly, P., Ducroix, A., England, P. & Goffin, V., 2010, In: Journal of Biological Chemistry. 285, 11, p. 8422-8433 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    DNA binding redistributes activation domain ensemble and accessibility in pioneer factor Sox2

    Bjarnason, S., McIvor, J. A. P., Prestel, Andreas, Demény, K. S., Bullerjahn, J. T., Kragelund, Birthe Brandt, Mercadante, D. & Heidarsson, P. O., 2024, In: Nature Communications. 15, 1, 16 p., 1445.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    DSS1/Sem1, a multifunctional and intrinsically disordered protein

    Kragelund, Birthe Brandt, Schenstrøm, S. M., Rebula, C. A., Panse, V. G. & Hartmann-Petersen, Rasmus, 2016, In: Trends in Biochemical Sciences. 41, 5, p. 446-459 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Deciphering the Alphabet of Disorder-Glu and Asp Act Differently on Local but Not Global Properties

    Roesgaard, M. A., Lundsgaard, J. E., Newcombe, Estella Anne, Jacobsen, Nina Louise, Pesce, Francesco, Tranchant, E. E., Lindemose, Søren, Prestel, Andreas, Hartmann-Petersen, Rasmus, Lindorff-Larsen, Kresten & Kragelund, Birthe Brandt, 2022, In: Biomolecules. 12, 10, 19 p., 1426.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Deoxynucleoside salvage in fission yeast allows rescue of ribonucleotide reductase deficiency but not Spd1-mediated inhibition of replication

    Fleck, O., Fahnøe, Ulrik, Løvschal, K. V., Gasasira, M. U., Marinova, I. N., Kragelund, Birthe Brandt, Carr, A. M., Hartsuiker, E., Holmberg, Christian & Nielsen, Olaf, 25 Apr 2017, In: Genes. 8, 5, 14 p., 128.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Development of prolactin receptor antagonists with reduced pH-dependence of receptor binding.

    Hansen, M. J. K., Olsen, Johan Gotthardt, Bernichtein, S., O'Shea, Charlotte, Sigurskjold, B. W., Goffin, V. & Kragelund, Birthe Brandt, 2011, In: Journal of Molecular Recognition. 24, 4, p. 533-547 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Different secondary structure elements as scaffolds for protein folding transition states of two homologous four-helix bundles

    Teilum, Kaare, Thormann, T., Caterer, N. R., Poulsen, H. I., Jensen, P. H., Knudsen, J., Kragelund, Birthe Brandt & Poulsen, F. M., 2005, In: Proteins - Structure Function and Bioinformatics. 59, 1, p. 80-90

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Direct single-molecule observation of calcium-dependent misfolding in human neuronal calcium sensor-1

    Heiðarsson, P. O., Naqvi, M. M., Otazo, M. R., Mossa, A., Kragelund, Birthe Brandt & Cecconi, C., 2014, In: Proceedings of the National Academy of Sciences U.S.A.. 111, 36, p. 13069-13074 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Disorder in a two-domain neuronal Ca2+-binding protein regulates domain stability and dynamics using ligand mimicry

    Staby, L., Kemplen, K. R., Stein, Amelie, Ploug, Michael, Clarke, J., Skriver, Karen, Heidarsson, P. O. & Kragelund, Birthe Brandt, 2021, In: Cellular and molecular life sciences : CMLS. 78, p. 2263-2278 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Distinct α-Synuclein:Lipid Co-Structure Complexes Affect Amyloid Nucleation through Fibril Mimetic Behavior

    Cholak, E., Bucciarelli, S., Bugge, K., Johansen, Nicolai Tidemand, Vestergaard, Bente, Arleth, Lise, Kragelund, Birthe Brandt & Langkilde, Annette Eva, Nov 2019, In: Biochemistry. 58, 50, p. 5052-5065

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Dss1 is a 26S proteasome ubiquitin receptor

    Paraskevopoulos, K., Kriegenburg, F., Tatham, M. H., Rösner, Heike Ilona, Medina, B., Larsen, I. B., Brandstrup, R., Hardwick, K. G., Hay, R. T., Kragelund, Birthe Brandt, Hartmann-Petersen, Rasmus & Gordon, C., 2014, In: Molecular Cell. 56, 3, p. 453-461 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published
  50. Published

    Dynamical Oligomerisation of Histidine Rich Intrinsically Disordered Proteins Is Regulated through Zinc-Histidine Interactions

    Cragnell, C., Staby, L., Lenton, S., Kragelund, Birthe Brandt & Skepö, M., 2019, In: Biomolecules. 9, 5, 20 p., 168.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Early kinetic intermediate in the folding of acyl-CoA binding protein detected by fluorescence labeling and ultrarapid mixing

    Teilum, Kaare, Maki, K., Kragelund, Birthe Brandt, Poulsen, F. M. & Roder, H., 2002, In: Proceedings of the National Academy of Science of the United States of America. 99, 15, p. 9807-12 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Effects of Ligand Binding on the Energy Landscape of Acyl-CoA-Binding Protein

    Sonar, P., Bellucci, L., Mossa, A., Heidarsson, P. O., Kragelund, Birthe Brandt & Cecconi, C., 2020, In: Biophysical Journal. 119, 9, p. 1821-1832 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Efficient refolding and reconstitution of tissue factor into nanodiscs facilitates structural investigation of a multicomponent system on a lipid bilayer

    Tidemand, Frederik Grønbæk, Østergaard, H., Ploug, Michael, Kragelund, Birthe Brandt & Arleth, Lise, 2020, In: Biochimica et Biophysica Acta - Biomembranes. 1862, 6, 10 p., 183214.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Engineering the substrate and inhibitor specificities of human coagulation Factor VIIa.

    Larsen, K. S., Østergaard, H., Bjelke, J. R., Olsen, O. H., Rasmussen, H. B., Christensen, L., Kragelund, Birthe Brandt & Stennicke, H. R., 2007, In: Biochemical Journal. 405, 3, p. 429-38 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Eukaryotic transcription factors: paradigms of protein intrinsic disorder

    Staby, L., O'Shea, Charlotte, Willemoës, Martin, Theisen, F., Kragelund, Birthe Brandt & Skriver, Karen, 12 Jul 2017, In: Biochemical Journal. 474, 15, p. 2509-2532 24 p.

    Research output: Contribution to journalReviewResearchpeer-review

  56. Published

    Evolution of A bHLH Interaction Motif

    Millard, P. S., Kragelund, Birthe Brandt & Burow, Meike, 2021, In: International Journal of Molecular Sciences. 22, 1, 18 p., 447.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Evolutionary conservation of the intrinsic disorder-based Radical-Induced Cell Death1 hub interactome

    Christensen, L. F., Staby, L., Bugge, K., O'Shea, Charlotte, Kragelund, Birthe Brandt & Skriver, Karen, 2019, In: Scientific Reports. 9, 15 p., 18927.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Evolutionary fine-tuning of residual helix structure in disordered proteins manifests in complex structure and lifetime

    Elkjær, Steffie Martina H, Due, Amanda Duncan, Christensen, L. F., Theisen, Frederik Friis, Staby, L., Kragelund, Birthe Brandt & Skriver, Karen, 2023, In: Communications Biology . 6, 11 p., 63.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Expanded Interactome of the Intrinsically Disordered Protein Dss1

    Schenstrøm, S. M., Rebula, C. A., Tatham, M. H., Hendus-Altenburger, R., Jourdain, I., Hay, R. T., Kragelund, Birthe Brandt & Hartmann-Petersen, Rasmus, 23 Oct 2018, In: Cell Reports. 25, 4, p. 862-870

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Exploiting hydrophobicity for efficient production of transmembrane helices for structure determination by NMR spectroscopy

    Bugge, K. Ø., Steinocher, H., Brooks, A. J., Lindorff-Larsen, Kresten & Kragelund, Birthe Brandt, 2015, In: Analytical Chemistry. 87, 18, p. 9126–9131 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Exploring the Protein-Membrane Interactions on the Intracellular Side of PRLR

    Araya-Secchi, R., Bugge, K., Kragelund, Birthe Brandt & Arleth, Lise, 7 Feb 2020, In: Biophysical Journal. 118, 3, Suppl.1, p. 57A-57A 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  62. Published

    Exploring the minimally frustrated energy landscape of unfolded ACBP

    Ozenne, V., Noel, J. K., Heiðarsson, P. O., Brander, S., Poulsen, F. M., Jensen, M. R., Kragelund, Birthe Brandt, Blackledge, M. & Danielsson, J. A., 2014, In: Journal of Molecular Biology. 426, 3, p. 722-734 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Extreme disorder in an ultrahigh-affinity protein complex

    Borgia, A., Borgia, M. B., Bugge, K. Ø., Kissling, V. M., Heidarsson, P. O., Fernandes, Catarina, Sottini, A., Soranno, A., Buholzer, K. J., Nettels, D., Kragelund, Birthe Brandt, Best, R. B. & Schuler, B., 1 Mar 2018, In: Nature. 555, p. 61-66 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Fast and one-step folding of closely and distantly related homologous proteins of a four-helix bundle family

    Kragelund, Birthe Brandt, Højrup, P., Jensen, M. S., Schjerling, C. K., Juul, E., Knudsen, J. & Poulsen, F., 1996, In: J. Mol. Biol.. 256, p. 187-200

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Flanking Disorder of the Folded αα-Hub Domain from Radical Induced Cell Death1 Affects Transcription Factor Binding by Ensemble Redistribution: Flanking disorder tunes the RCD1-RST ensemble

    Staby, L., Due, Amanda Duncan, Kunze, M. B. A., Jørgensen, M. L. M., Skriver, Karen & Kragelund, Birthe Brandt, 2021, In: Journal of Molecular Biology. 433, 24, 15 p., 167320.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Fluorescently labelled bovine acyl-CoA-binding protein acting as an acyl-CoA sensor: interaction with CoA and acyl-CoA esters and its use in measuring free acyl-CoA esters and non-esterified fatty acids

    Wadum, M. C., Villadsen, J. K., Feddersen, S., Moller, R. S., Neergaard, T. B., Kragelund, Birthe Brandt, Hojrup, P., Faergeman, N. J. & Knudsen, J., 2002, In: Biochemical Journal. 365, p. 165-172 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Folding of a four-helix bundle. Studies of acyl-coenzyme A binding protein

    Kragelund, Birthe Brandt, Robinson, C. R., Knudsen, J., Dobson, C. M. & Poulsen, F., 1995, In: Biochemistry. 34, p. 7217-7224

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Formation of hydrogen bonds precedes the rate-limiting formation of persistent structure in the folding of ACBP

    Teilum, Kaare, Kragelund, Birthe Brandt, Knudsen, J. & Poulsen, F. M., 2000, In: Journal of Molecular Biology. 301, 5, p. 1307-14 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Functional aspects of protein flexibility

    Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2009, In: Cellular and Molecular Life Sciences. 66, 14, p. 2231-47 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Functional characterization of a conserved archaeal viral operon revealing single-stranded DNA binding, annealing and nuclease activities

    Guo, Y., Kragelund, Birthe Brandt, White, M. F. & Peng, Xu, 2015, In: Journal of Molecular Biology. 427, 12, p. 2179-2191 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Functions of intrinsic disorder in transmembrane proteins

    Kjærgaard, M. & Kragelund, Birthe Brandt, Sep 2017, In: Cellular and Molecular Life Sciences. 74, 17, p. 3205-3224 20 p.

    Research output: Contribution to journalReviewResearchpeer-review

  72. Published

    Gentamicin binds to the megalin receptor as a competitive inhibitor using the common ligand binding motif of complement type repeats: insight from the nmr structure of the 10th complement type repeat domain alone and in complex with gentamicin

    Dagil, Robert, O'Shea, Charlotte, Nykjær, A., Bonvin, A. M. J. J. & Kragelund, Birthe Brandt, 2013, In: The Journal of Biological Chemistry. 288, 6, p. 4424-35 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Globular and disordered-the non-identical twins in protein-protein interactions

    Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2015, In: Frontiers in Bioscience. 2, 6 p., 40.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    How phosphorylation impacts intrinsically disordered proteins and their function

    Newcombe, Estella Anne, Delaforge, Elise, Hartmann-Petersen, Rasmus, Skriver, Karen & Kragelund, Birthe Brandt, 2022, In: Essays in Biochemistry. 66, 7, p. 901-913 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  75. Hydrophobic core substitutions in calbindin D9k: effects on Ca2+ binding and dissociation

    Kragelund, Birthe Brandt, Jönsson, M., Bifulco, G., Chazin, W. J., Nilsson, H., Finn, B. E. & Linse, S., 23 Jun 1998, In: Biochemistry. 37, 25, p. 8926-37 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Hydroxylation of the Herbicide Isoproturon by Fungi Isolated from Agricultural soil

    Rønhede, S., Jensen, B., Rosendahl, Søren, Kragelund, Birthe Brandt, Juhler, R. K. & Aamand, J., 2005, In: Applied and Environmental Microbiology. 71, 12, p. 7927-7932

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    IDDomainSpotter: Compositional bias reveals domains in long disordered protein regions—Insights from transcription factors

    Millard, P. S., Bugge, K., Marabini, R., Boomsma, Wouter, Burow, Meike & Kragelund, Birthe Brandt, 2020, In: Protein Science. 29, 1, p. 169-183 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Insight into Calcium-Binding Motifs of Intrinsically Disordered Proteins

    Newcombe, Estella Anne, Fernandes, Catarina, Lundsgaard, J. E., Brakti, Inna, Lindorff-Larsen, Kresten, Langkilde, Annette Eva, Skriver, Karen & Kragelund, Birthe Brandt, 2021, In: Biomolecules. 11, 8, 17 p., 1173.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Interactions by Disorder - A Matter of Context

    Bugge, K., Brakti, Inna, Fernandes, Catarina, Dreier, J. E., Lundsgaard, J. E., Olsen, Johan Gotthardt, Skriver, Karen & Kragelund, Birthe Brandt, 2020, In: Frontiers in Molecular Biosciences. 7, 16 p., 110.

    Research output: Contribution to journalReviewResearchpeer-review

  80. Published

    Intrinsically Disordered Proteins: Methods and Protocols

    Skriver, Karen (ed.) & Kragelund, Birthe Brandt (ed.), 2020, New York: Humana Press. 777 p. (Methods in Molecular Biology, Vol. 2141).

    Research output: Book/ReportBookResearchpeer-review

  81. Published

    Intrinsically Disordered Proteins as an Instrument for Research-Integrating Teaching

    Skriver, K., Sjørup, S. A., Langkilde, A. E., Balouka, E., Christensen, C. S., Carbel, K., Decker, J. N. V., Essenbæk, D. N., Gräf, J. F., Jessen, C. H., Kristensen, P., Merrild, C., Mortensen, T. S., Nalepa, I. F., Nordsteen, B. W., Svoren, S. K., van Hall, M., Weicher, J., Wind, M. L., Zhang, D. & 8 others, Saar, Daniel, Blæsild, H., Stahlhut, M., Andersen, K. V., Dagil, Robert, Vestergaard, Bente, Ryberg, Marie L. & Kragelund, Birthe Brandt, 2023, In: The Biophysicist. 4 , 2, p. 1-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Intrinsically disordered cytoplasmic domains of two cytokine receptors mediate conserved interactions with membranes

    Haxholm, G. W., Nikolajsen, L. F., Olsen, Johan Gotthardt, Fredsted, J., Larsen, F. H., Goffin, V., Pedersen, Stine Helene Falsig, Brooks, A. J., Waters, M. J. & Kragelund, Birthe Brandt, 2015, In: Biochemical Journal. 468, 3, p. 495-506 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Local perturbations by ligand binding on hydrogen exchange kinetics in a four-helix bundle protein, acyl-coenzyme A binding protein (ACBP)

    Kragelund, Birthe Brandt, Knudsen, J. & Poulsen, F., 1995, In: J. Mol. Biol.. 250, p. 695-706

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Mapping the lifetimes of local opening events in a native state protein

    Kragelund, Birthe Brandt, Heinemann, B., Knudsen, J. & Poulsen, F., 1998, In: Protein Sci.. 7, p. 2237-2248

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Mechanism of the Ca2+-induced enhancement of the intrinsic factor VIIa activity

    Bjelke, J. R., Olsen, O. H., Fodje, M., Svensson, L. A., Bang, S., Bolt, G., Kragelund, Birthe Brandt & Persson, E., 2008, In: Journal of Biological Chemistry. 283, 38, p. 25863-70 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Metabolites of the phenylurea herbicides chlorotoluron, diuron, isoproturonand linuron produced by the soil fungus Mortierella sp.

    Badawi, N., Rønhede, S., Olsson, S., Kragelund, Birthe Brandt, Johnsen, A. H., Jacobsen, O. S. & Aamand, J., 2009, In: Environmental Pollution. 157, 10, p. 2806-2812 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Modeling of flexible membrane-bound biomolecular complexes for solution small-angle scattering

    Barclay, A., Kragelund, Birthe Brandt, Arleth, Lise & Pedersen, Martin Cramer, Apr 2023, In: Journal of Colloid and Interface Science. 635, p. 611-621 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Molecular basis for the binding and selective dephosphorylation of Na+/H+ exchanger 1 by calcineurin

    Hendus-Altenburger, R., Wang, X., Sjøgaard-Frich, Lise Margrethe, Pedraz Cuesta, E., Sheftic, S. R., Bendsøe, A. H., Page, R., Kragelund, Birthe Brandt, Pedersen, Stine Helene Falsig & Peti, W., 2019, In: Nature Communications. 10, 13 p., 3489.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Molecular insights into alginate beta-lactoglobulin A multivalencies: The foundation for their amorphous aggregates and coacervation

    Madsen, M., Prestel, Andreas, Madland, E., Westh, P., Tondervik, A., Sletta, H., Peters, G. H. J., Aachmann, F. L. L., Kragelund, Birthe Brandt & Svensson, B., 2023, In: Protein Science. 32, 2, 15 p., 4556.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Molecular switching in transcription through splicing and proline-isomerization regulates stress responses in plants

    Theisen, Frederik Friis, Prestel, Andreas, Elkjær, Steffie Martina H, Leurs, Y. H. A., Morffy, N., Strader, L. C., O'Shea, Charlotte, Teilum, Kaare, Kragelund, Birthe Brandt & Skriver, Karen, 2024, In: Nature Communications. 15, 1, 13 p., 592.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Monomeric α-synuclein activates the plasma membrane calcium pump

    Kowalski, A., Betzer, C., Larsen, S. T., Gregersen, E., Newcombe, Estella Anne, Bermejo, M. C., Bendtsen, V. W., Diemer, J., Ernstsen, C. V., Jain, S., Bou, A. E., Langkilde, Annette Eva, Nejsum, L. N., Klipp, E., Edwards, R., Kragelund, Birthe Brandt, Jensen, P. H. & Nissen, Poul, 2023, In: EMBO Journal. 42, 23, 21 p., e111122.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Mutations in a Single Signaling Pathway Allow Cell Growth in Heavy Water

    Kampmeyer, Caroline, Johansen, Jens Vilstrup, Holmberg, Christian, Karlson, M., Gersing, S. K., Nunes Bordallo, Heloisa, Kragelund, Birthe Brandt, Lerche, M. H., Jourdain, I., Winther, Jakob R. & Hartmann-Petersen, Rasmus, 2020, In: A C S Synthetic Biology. 9, 4, p. 733-748 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Myotubularin-related-protein-7 inhibits mutant (G12V) K-RAS by direct interaction

    Weidner, P., Saar, D., Söhn, M., Schroeder, T., Yu, Y., Zöllner, F. G., Ponelies, N., Zhou, X., Zwicky, A., Rohrbacher, F. N., Pattabiraman, V. R., Tanriver, M., Bauer, A., Ahmed, H., Ametamey, S. M., Riffel, P., Seger, R., Bode, J. W., Wade, R. C., Ebert, M. P. A. & 2 others, Kragelund, Birthe Brandt & Burgermeister, E., 2024, In: Cancer Letters. 588, 19 p., 216783.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    New horizons for lipoprotein receptors: communication by β-propellers

    Andersen, O. M., Dagil, Robert & Kragelund, Birthe Brandt, 2013, In: Journal of Lipid Research. 54, p. 2763-2774 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    On the Potential of Machine Learning to Examine the Relationship Between Sequence, Structure, Dynamics and Function of Intrinsically Disordered Proteins

    Lindorff-Larsen, Kresten & Kragelund, Birthe Brandt, 2021, In: Journal of Molecular Biology. 433, 20, 22 p., 167196.

    Research output: Contribution to journalReviewResearchpeer-review

  96. Published

    On the specificity of protein-protein interactions in the context of disorder

    Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2021, In: Biochemical Journal. 478, 11, p. 2035-2050 16 p.

    Research output: Contribution to journalReviewResearchpeer-review

  97. Published

    Orchestration of signaling by structural disorder in class 1 cytokine receptors

    Seiffert, P., Bugge, K., Nygaard, M., Haxholm, G. W., Martinsen, J. H., Pedersen, M. N., Arleth, Lise, Boomsma, Wouter & Kragelund, Birthe Brandt, 24 Aug 2020, In: Cell Communication and Signaling. 18, 1, 30 p., 132.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Order and disorder - An integrative structure of the full-length human growth hormone receptor

    Kassem, N., Araya-Secchi, R., Bugge, K., Barclay, A., Steinocher, H., Khondker, A., Wang, Y., Lenard, A. J., Bürck, J., Sahin, Cagla, Ulrich, A. S., Landreh, M., Pedersen, Martin Cramer, Rheinstädter, M. C., Pedersen, Per Amstrup, Lindorff-Larsen, Kresten, Arleth, Lise & Kragelund, Birthe Brandt, 2021, In: Science Advances. 7, 27, 20 p., eabh3805.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Order by disorder in plant signaling

    Kragelund, Birthe Brandt, Jensen, M. K. & Skriver, Karen, 2012, In: Trends in Plant Science. 17, 11, p. 625-632 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    PPARγ antagonists induce aromatase transcription in adipose tissue cultures

    Ardenkjær-Skinnerup, J., Saar, Daniel, Petersen, Patricia Stephanie S, Pedersen, M., Svingen, T., Kragelund, Birthe Brandt, Hadrup, N., Ravn-Haren, G., Emanuelli, Brice, Brown, K. A. & Vogel, U., 2024, In: Biochemical Pharmacology. 222, 13 p., 116095.

    Research output: Contribution to journalJournal articleResearchpeer-review

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