Birthe Brandt Kragelund

Birthe Brandt Kragelund

Professor


  1. 1993
  2. Published

    Threedimensional structure of the complex acyl-coenzyme, A binding protein and palmitoyl-coenzyme A

    Kragelund, Birthe Brandt, Andersen, K. V., Madsen, J. C., Knudsen, J. & Poulsen, F., 1993, In: J. Mol. Biol.. 230, p. 1260-1277

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 1995
  4. Published

    Folding of a four-helix bundle. Studies of acyl-coenzyme A binding protein

    Kragelund, Birthe Brandt, Robinson, C. R., Knudsen, J., Dobson, C. M. & Poulsen, F., 1995, In: Biochemistry. 34, p. 7217-7224

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Local perturbations by ligand binding on hydrogen exchange kinetics in a four-helix bundle protein, acyl-coenzyme A binding protein (ACBP)

    Kragelund, Birthe Brandt, Knudsen, J. & Poulsen, F., 1995, In: J. Mol. Biol.. 250, p. 695-706

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 1996
  7. Published

    Thermodynamics of ligand binding to acyl-coenzyme, A binding protein studied by titration calometry

    Færgeman, N. J., Sigurskjold, B. W., Kragelund, Birthe Brandt, Andersen, K. V. & Knudsen, J., 1996, In: Biochemistry. 35, p. 14118-14126

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Fast and one-step folding of closely and distantly related homologous proteins of a four-helix bundle family

    Kragelund, Birthe Brandt, Højrup, P., Jensen, M. S., Schjerling, C. K., Juul, E., Knudsen, J. & Poulsen, F., 1996, In: J. Mol. Biol.. 256, p. 187-200

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Probing the nature of non-covalent interactions by mass spectrometry. A study of protein-CoA ligand interactions and assembly

    Robinson, C. R., Chung, E. W., Kragelund, Birthe Brandt, Knudsen, J., Aplin, R. T., Poulsen, F. & Dobson, C. M., 1996, In: J. Amer. Chem.. 118, p. 8646-8653

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 1997
  11. Published

    Structure of lipid-transfer protein complexed with palmitoyl-CoA. A hydrophobic binding site expandable to fit both large and small lipid-like ligands

    Lerche, M. H., Kragelund, Birthe Brandt, Bech, L. & Poulsen, F., 1997, In: Structure. 5, p. 291-306

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 1998
  13. Hydrophobic core substitutions in calbindin D9k: effects on Ca2+ binding and dissociation

    Kragelund, Birthe Brandt, Jönsson, M., Bifulco, G., Chazin, W. J., Nilsson, H., Finn, B. E. & Linse, S., 23 Jun 1998, In: Biochemistry. 37, 25, p. 8926-37 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Mapping the lifetimes of local opening events in a native state protein

    Kragelund, Birthe Brandt, Heinemann, B., Knudsen, J. & Poulsen, F., 1998, In: Protein Sci.. 7, p. 2237-2248

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 1999
  16. Published

    Acyl-coenzyme A binding protein (ACBP)

    Kragelund, Birthe Brandt, Knudsen, J. & Poulsen, F. M., 23 Nov 1999, In: B B A - Reviews on Cancer. 1441, 2-3, p. 150-61 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. The formation of a native-like structure containing eight conserved hydrophobic residues is rate limiting in two-state protein folding of ACBP

    Kragelund, Birthe Brandt, Osmark, P., Neergaard, T. B., Schiødt, J., Kristiansen, K., Knudsen, J. & Poulsen, F., 1999, In: Nature Structural and Molecular Biology. 6, 6, p. 594-601

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2000
  19. Published

    1H, 13C, and 15N assignments of un-myristoylated Ca2+-frequenin, a synaptic efficacy modulator

    Kragelund, Birthe Brandt, Hauenschild, A., Carlström, G., Pongs, O. & Finn, B. E., Jan 2000, In: Journal of Biomolecular N M R. 16, 1, p. 85-6 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Formation of hydrogen bonds precedes the rate-limiting formation of persistent structure in the folding of ACBP

    Teilum, Kaare, Kragelund, Birthe Brandt, Knudsen, J. & Poulsen, F. M., 2000, In: Journal of Molecular Biology. 301, 5, p. 1307-14 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2002
  22. Published

    Early kinetic intermediate in the folding of acyl-CoA binding protein detected by fluorescence labeling and ultrarapid mixing

    Teilum, Kaare, Maki, K., Kragelund, Birthe Brandt, Poulsen, F. M. & Roder, H., 2002, In: Proceedings of the National Academy of Science of the United States of America. 99, 15, p. 9807-12 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Transient structure formation in unfolded acyl-coenzyme A-binding protein observed by site-directed spin labelling

    Teilum, Kaare, Kragelund, Birthe Brandt & Poulsen, F. M., 2002, In: Journal of Molecular Biology. 324, 2, p. 349-57 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Transient intermediary states with high and low folding probabilities in the apparent two-state folding equilibrium of ACBP at low pH

    Thomsen, J. K., Kragelund, Birthe Brandt, Teilum, Kaare, Knudsen, J. & Poulsen, F. M., 2002, In: Journal of Molecular Biology. 318, 3, p. 805-14 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Fluorescently labelled bovine acyl-CoA-binding protein acting as an acyl-CoA sensor: interaction with CoA and acyl-CoA esters and its use in measuring free acyl-CoA esters and non-esterified fatty acids

    Wadum, M. C., Villadsen, J. K., Feddersen, S., Moller, R. S., Neergaard, T. B., Kragelund, Birthe Brandt, Hojrup, P., Faergeman, N. J. & Knudsen, J., 2002, In: Biochemical Journal. 365, p. 165-172 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2003
  27. Published

    Universitetsstuderendes tilgang til eksperimentelt udstyr - kønslige og faglige aspekter

    Bruun, G. M., Kragelund, Birthe Brandt & Oddershede, L. B., 2003, In: Center for Naturfagenes Didaktiks Tidsskriftserie. 9, p. .

    Research output: Contribution to journalJournal articleResearch

  28. Published

    Universitetsstuderendes tilgang til eksperimentelt udstyr - faglige og kønslige aspekter

    Bruun, G. M., Kragelund, Birthe Brandt & Oddershede, L. B., 2003, Natureveidenskabs didaktik. Museum Tusculanum, Vol. 9. p. 1-37

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  29. 2004
  30. Published

    Structure and biochemical function of a prototypical Arabidopsis U-box domain

    Andersen, P., Kragelund, Birthe Brandt, Olsen, A. N., Larsen, F. H., Chua, N., Poulsen, F. M. & Skriver, Karen, 2004, In: Journal of Biological Chemistry. 279, 38, p. 40053-40061 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2005
  32. Published

    Reversible Dimerization of Acid-Denatured ACBP Controlled by Helix A4

    Fieber, W., Kragelund, Birthe Brandt, Meldal, Morten Peter & Poulsen, F. M., 2005, In: Biochemistry. 44, 5, p. 1375-1384

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Protein folding: Defining a standard set of experimental conditions and a preliminary kinetic data set of two-state proteins

    Maxwell, K. L., Wildes, D., Zarrine-Afsar, A., Rivos, M. A. D. L. R., Brown, A. G., Friel, C. T., Hedberg, L., Horng, J-C., Bona, D., Miller, E. J., Vallée-Bélisle, A., Main, E. R. G., Bemporad, F., Qiu, L., Teilum, K., Vu, N-D., Edwards, A. M., Ruczinski, I., Poulsen, F. M., Kragelund, B. B. & 14 others, Michnick, S. W., Chiti, F., Bai, Y., Hagen, S. J., Serrano, L., Oliveberg, M., Raleigh, D. P., Stafshede, P. W., Radford, S. E., Jackson, S. E., Sosnick, T. R., Margusee, S., Davidson, A. R. & Plaxco, K. W., 2005, In: Protein Science. 14, 3, p. 602-616

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Hydroxylation of the Herbicide Isoproturon by Fungi Isolated from Agricultural soil

    Rønhede, S., Jensen, B., Rosendahl, Søren, Kragelund, Birthe Brandt, Juhler, R. K. & Aamand, J., 2005, In: Applied and Environmental Microbiology. 71, 12, p. 7927-7932

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Application of Hydrogen Exchange Kinetics to Studies of Protein Folding

    Teilum, Kaare, Kragelund, Birthe Brandt & Poulsen, F. M., 2005, Protein Folding Handbook. Buchner, J. & Kiefhaber, T. (eds.). Weinheim: Wiley-VCH, p. 634-672

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  36. Published

    Different secondary structure elements as scaffolds for protein folding transition states of two homologous four-helix bundles

    Teilum, Kaare, Thormann, T., Caterer, N. R., Poulsen, H. I., Jensen, P. H., Knudsen, J., Kragelund, Birthe Brandt & Poulsen, F. M., 2005, In: Proteins - Structure Function and Bioinformatics. 59, 1, p. 80-90

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Solution structure of human prolactin

    Teilum, Kaare, Hoch, J. C., Goffin, V., Kinet, S., Martial, J. A. & Kragelund, Birthe Brandt, 2005, In: Journal of Molecular Biology. 351, 4, p. 810-23 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. 2006
  39. Published

    A loop of coagulation factor VIIa influencing macromolecular substrate specificity.

    Bjelke, J. R., Persson, E., Rasmussen, H. B., Kragelund, Birthe Brandt & Olsen, O. H., 2006, In: FEBS Letters. 581, 1, p. 71-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Binding site structure of one LRP-RAP complex: implications for a common ligand-receptor binding motif.

    Jensen, G. A., Andersen, O. M., Bonvin, A. M. J. J., Bjerrum-Bohr, I., Etzerodt, M., Thøgersen, H. C., O'Shea, Charlotte, Poulsen, F. M. & Kragelund, Birthe Brandt, 2006, In: Journal of Molecular Biology. 362, 4, p. 700-16 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. 2007
  42. Published

    Structure of the human beta-ketoacyl [ACP] synthase from the mitochondrial type II fatty acid synthase

    Christensen, Caspar Elo, Kragelund, Birthe Brandt, Von Wettstein-Knowles, P. & Henriksen, A., Feb 2007, In: Protein Science. 16, 2, p. 261-272

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Acyl-CoA binding proteins; structural and functional conservation over 2000 MYA.

    Faergeman, N. J., Wadum, M., Feddersen, S., Burton, M., Kragelund, Birthe Brandt & Knudsen, J., 2007, In: Molecular and Cellular Biochemistry. 299, 1-2, p. 55-65 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Structural and thermodynamic bases for the design of pure prolactin receptor antagonists: X-ray structure of Del1-9-G129R-hPRL.

    Jomain, J., Tallet, E., Broutin, I., Hoos, S., van Agthoven, J., Ducruix, A., Kelly, P. A., Kragelund, Birthe Brandt, England, P. & Goffin, V., 2007, In: Journal of Biological Chemistry. 282, 45, p. 33118-31 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Engineering the substrate and inhibitor specificities of human coagulation Factor VIIa.

    Larsen, K. S., Østergaard, H., Bjelke, J. R., Olsen, O. H., Rasmussen, H. B., Christensen, L., Kragelund, Birthe Brandt & Stennicke, H. R., 2007, In: Biochemical Journal. 405, 3, p. 429-38 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Structure-activity study of the antibacterial peptide fallaxin

    Søndergaard, S. L., Frimodt-Møller, N., Kragelund, Birthe Brandt & Hansen, Paul Robert, 2007, In: Protein Science. 16, 9, p. 1969-1976 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. 2008
  48. Published

    Mechanism of the Ca2+-induced enhancement of the intrinsic factor VIIa activity

    Bjelke, J. R., Olsen, O. H., Fodje, M., Svensson, L. A., Bang, S., Bolt, G., Kragelund, Birthe Brandt & Persson, E., 2008, In: Journal of Biological Chemistry. 283, 38, p. 25863-70 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    The intrinsically disordered RNR inhibitor Sml1 is a dynamic dimer

    Danielsson, J., Liljedahl, L., Ba´ra´ny-Wallje, E., Sønderby, P., Kristensen, L. H., Martinez-Yamout, M. A., Dyson, H. J., Wright, P. E., Poulsen, F. M., Ma¨ler, L., Gra¨slund, A. & Kragelund, Birthe Brandt, 2008, In: Biochemistry. 47, 50, p. 13428-13437 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Acyl-CoA-binding protein (ACBP) localizes to the endoplasmic reticulum and Golgi in a ligand-dependent manner in mammalian cells.

    Hansen, J. S., Færgeman, N. J., Kragelund, Birthe Brandt & Knudsen, J., 2008, In: Biochemical Journal. 410, 3, p. 463-472 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Phosphate Selective Uranyl Photo-Affinity Cleavage of Proteins. Determination of Phosphorylation Sites.

    Kristensen, L. H., Nielsen, Peter E., Jørgensen, C. I., Kragelund, Birthe Brandt & Møllegaard, Niels Erik, 2008, In: ChemBioChem. 9, 15, p. 2377-81 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. 2009
  53. Published

    Metabolites of the phenylurea herbicides chlorotoluron, diuron, isoproturonand linuron produced by the soil fungus Mortierella sp.

    Badawi, N., Rønhede, S., Olsson, S., Kragelund, Birthe Brandt, Johnsen, A. H., Jacobsen, O. S. & Aamand, J., 2009, In: Environmental Pollution. 157, 10, p. 2806-2812 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Structure of the Mature Streptococcal Cysteine Protease Exotoxin mSpeB in Its Active Dimeric Form

    Olsen, Johan Gotthardt, Dagil, Robert, Niclasen, L. M., Sørensen, O. E. & Kragelund, Birthe Brandt, 2009, In: Journal of Molecular Biology. 393, 3, p. 693-703 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Functional aspects of protein flexibility

    Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2009, In: Cellular and Molecular Life Sciences. 66, 14, p. 2231-47 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. 2010
  57. Published

    Crystal structure of an affinity-matured prolactin complexed to its dimerized receptor reveals the topology of hormone binding site 2.

    Broutin, I., Jomain, J., Tallet, E., Van Agthoven, J., Raynal, B., Hoos, S., Kragelund, Birthe Brandt, Kelly, P., Ducroix, A., England, P. & Goffin, V., 2010, In: Journal of Biological Chemistry. 285, 11, p. 8422-8433 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Temperature-dependent structural changes in intrinsically disordered proteins: formation of alpha-helices or loss of polyproline II?

    Kjærgaard, M., Nørholm, A., Hendus-Altenburger, R., Pedersen, Stine Helene Falsig, Poulsen, F. M. & Kragelund, Birthe Brandt, 1 Aug 2010, In: Protein Science. 19, 8, p. 1555-64 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Regulation of ribonucleotide reductase by Spd1 involves multiple mechanisms

    Nestoras, K., Mohammed, A. H., Schreurs, A., Fleck, O., Watson, A. T., Poitelea, M., O'Shea, Charlotte, Chahwan, C., Holmberg, Christian, Kragelund, Birthe Brandt, Nielsen, Olaf, Osborne, M., Carr, A. M. & Liu, C., 1 Jun 2010, In: Genes & Development. 24, 11, p. 1145-1159 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    A Far UV CD study of de novo designed antimicrobial coiled coils upon interaction with model membranes

    Søndergaard, S. L., Kragelund, Birthe Brandt, Thulstrup, Peter Waaben, Brahm, Jesper, Siegumfeldt, Henrik, Frimodt-Møller, N. & Hansen, Paul Robert, 2010, In: Journal of Peptide Science. S2

    Research output: Contribution to journalConference abstract in journalResearch

  61. 2011
  62. Published

    Development of prolactin receptor antagonists with reduced pH-dependence of receptor binding.

    Hansen, M. J. K., Olsen, Johan Gotthardt, Bernichtein, S., O'Shea, Charlotte, Sigurskjold, B. W., Goffin, V. & Kragelund, Birthe Brandt, 2011, In: Journal of Molecular Recognition. 24, 4, p. 533-547 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Senescence-associated barley NAC (NAM, ATAF1,2, CUC) transcription factor interacts with radical-induced cell death 1 through a disordered regulatory domain

    Kjaersgaard, T., Jensen, M. K., Christiansen, M. W., Gregersen, P. L., Kragelund, Birthe Brandt & Skriver, Karen, 2011, In: Journal of Biological Chemistry. 286, 41, p. 35418-29 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Streptococcal pyogenic exotoxin B (SpeB) boosts the contact system via binding of a-1 antitrypsin

    Meinert Niclasen, L., Olsen, Johan Gotthardt, Dagil, Robert, Qing, Z., Sørensen, O. E. & Kragelund, Birthe Brandt, 2011, In: Biochemical Journal. 434, 1, p. 123-32 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    The Intracellular Distal Tail of the Na+/H+ Exchanger NHE1 Is Intrinsically Disordered: Implications for NHE1 Trafficking

    Nørholm, A., Hendus-Altenburger, R., Bjerre, G., Kjærgaard, M., Pedersen, Stine Helene Falsig & Kragelund, Birthe Brandt, 2011, In: Biochemistry. 50, 17, p. 3469-80 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Protein stability, flexibility and function

    Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2011, In: B B A - Proteins and Proteomics. 1814, 8, p. 969-76 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  67. 2012
  68. Published

    The WSXWS motif in cytokine receptors is a molecular switch involved in receptor activation: insight from structures of the prolactin receptor

    Dagil, Robert, Knudsen, M. J., Olsen, Johan Gotthardt, O'Shea, Charlotte, Franzmann, M., Goffin, V., Teilum, Kaare, Breinholt, J. & Kragelund, Birthe Brandt, 2012, In: Structure. 20, 2, p. 270-282 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    β-Microseminoprotein endows post coital seminal plasma with potent candidacidal activity by a calcium- and pH-dependent mechanism.

    Edström Hägerwall, A., Rydengård, V., Fernlund, P., Mörgelin, M., Baumgarten, M., Cole, A. M., Malmsten, M., Kragelund, Birthe Brandt & Sørensen, O. E., 2012, In: P L o S Pathogens. 8, 4, p. 1-12 12 p., e1002625.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    A highly compliant protein native state with a spontaneous-like mechanical unfolding pathway

    Heiðarsson, P. O., Valpapuram, I., Camilloni, C., Imparato, A., Tiana, G., Poulsen, F. M., Kragelund, Birthe Brandt & Cecconi, C., 2012, In: Journal of the American Chemical Society. 134, 41, p. 17068-17075 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    The C-terminal tail of human neuronal calcium sensor 1 regulates the conformational stability of the Ca2+-activated state

    Heiðarsson, P. O., Bjerrum-Bohr, I. J., Jensen, G. A., Pongs, O., Finn, B. E., Poulsen, F. M. & Kragelund, Birthe Brandt, 2012, In: Journal of Molecular Biology. 417, 1-2, p. 51-64 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Analyzing temperature-induced transitions in disordered proteins by NMR spectroscopy and secondary chemical shift analyses

    Kjærgaard, M., Poulsen, F. M. & Kragelund, Birthe Brandt, 2012, Intrinsically disordered protein analysis: methods and experimental tools. Uversky, V. N. & Dunker, A. K. (eds.). Springer, Vol. 2. p. 249-256 8 p. (Methods in Molecular Biology, Vol. 896).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  73. Published

    Temperature-induced transitions in disordered proteins probed by NMR spectroscopy

    Kjærgaard, M., Poulsen, F. M. & Kragelund, Birthe Brandt, 2012, Intrinsically disordered protein analysis: methods and experimental tools. Uversky, V. N. & Dunker, A. K. (eds.). Springer, Vol. 2. p. 233-247 15 p. (Methods in Molecular Biology, Vol. 896).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  74. Published

    Order by disorder in plant signaling

    Kragelund, Birthe Brandt, Jensen, M. K. & Skriver, Karen, 2012, In: Trends in Plant Science. 17, 11, p. 625-632 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Structure and Dynamic Properties of Membrane Proteins using NMR

    Rösner, Heike Ilona & Kragelund, Birthe Brandt, 2012, In: Comprehensive Physiology. 2, 2, p. 1491-1539 49 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. 2013
  77. Published

    New horizons for lipoprotein receptors: communication by β-propellers

    Andersen, O. M., Dagil, Robert & Kragelund, Birthe Brandt, 2013, In: Journal of Lipid Research. 54, p. 2763-2774 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Gentamicin binds to the megalin receptor as a competitive inhibitor using the common ligand binding motif of complement type repeats: insight from the nmr structure of the 10th complement type repeat domain alone and in complex with gentamicin

    Dagil, Robert, O'Shea, Charlotte, Nykjær, A., Bonvin, A. M. J. J. & Kragelund, Birthe Brandt, 2013, In: The Journal of Biological Chemistry. 288, 6, p. 4424-35 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Strains of the soil fungus Mortierella show different degradation potentials for the phenylurea herbicide diuron

    Ellegaard-Jensen, L., Aamand, J., Kragelund, Birthe Brandt, Johnsen, A. H. & Rosendahl, Søren, 2013, In: Biodegradation. 24, 6, p. 765-774 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Single-molecule folding mechanism of an EF-hand neuronal calcium sensor

    Heiðarsson, P. O., Otazo, M. R., Bellucci, L., Mossa, A., Imparato, A., Paci, E., Corni, S., Felice, R. D., Kragelund, Birthe Brandt & Cecconi, C., 2013, In: Structure. 21, 10, p. 1812-1821 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Solution properties of the archaeal CRISPR DNA repeat-binding homeodomain protein Cbp2

    Kenchappa, C., Heiðarsson, P. O., Kragelund, Birthe Brandt, Garrett, Roger Antony & Poulsen, F., 2013, In: Nucleic Acids Research. 41, 5, p. 3424-3435 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    The transcriptional repressor domain of Gli3 is intrinsically disordered

    Tsanev, R., Vanatalu, K., Jarvet, J., Tanner, R., Laur, K., Tiigimägi, P., Kragelund, Birthe Brandt, Østerlund, T. & Kogerman, P., 2013, In: PLoS ONE. 8, 10, 9 p., e76972.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. 2014
  84. Published

    Direct single-molecule observation of calcium-dependent misfolding in human neuronal calcium sensor-1

    Heiðarsson, P. O., Naqvi, M. M., Otazo, M. R., Mossa, A., Kragelund, Birthe Brandt & Cecconi, C., 2014, In: Proceedings of the National Academy of Sciences U.S.A.. 111, 36, p. 13069-13074 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Structural dynamics and regulation of the mammalian SLC9A family of Na+/H+ exchangers

    Hendus-Altenburger, R., Kragelund, Birthe Brandt & Pedersen, Stine Helene Falsig, 2014, Current Topics in Membranes: Exchangers. Bevensee, M. O. (ed.). Elsevier, Vol. 73. p. 69-148 80 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  86. Published

    Who climbs the tryptophan ladder? On the structure and function of the WSXWS motif in cytokine receptors and thrombospondin repeats

    Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2014, In: Cytokine & Growth Factor Reviews. 25, 3, p. 337-341 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  87. Published

    Exploring the minimally frustrated energy landscape of unfolded ACBP

    Ozenne, V., Noel, J. K., Heiðarsson, P. O., Brander, S., Poulsen, F. M., Jensen, M. R., Kragelund, Birthe Brandt, Blackledge, M. & Danielsson, J. A., 2014, In: Journal of Molecular Biology. 426, 3, p. 722-734 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Dss1 is a 26S proteasome ubiquitin receptor

    Paraskevopoulos, K., Kriegenburg, F., Tatham, M. H., Rösner, Heike Ilona, Medina, B., Larsen, I. B., Brandstrup, R., Hardwick, K. G., Hay, R. T., Kragelund, Birthe Brandt, Hartmann-Petersen, Rasmus & Gordon, C., 2014, In: Molecular Cell. 56, 3, p. 453-461 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    CECAM workshop on intrinsically disordered proteins

    Rösner, Heike Ilona, Papaleo, E., Haxholm, G. W., Best, R. B., Kragelund, Birthe Brandt & Lindorff-Larsen, Kresten, 2014, In: Intrinsically Disordered Proteins. 2, 1, p. 1-5 5 p.

    Research output: Contribution to journalConference abstract in journalResearch

  90. Published

    Spd2 assists Spd1 in the modulation of ribonucleotide reductase architecture but does not regulate deoxynucleotide pools

    Vejrup-Hansen, R., Fleck, O., Landvad, K., Fahnøe, Ulrik, Broendum, S. S., Schreurs, A., Kragelund, Birthe Brandt, Carr, A. M., Holmberg, Christian & Nielsen, Olaf, 2014, In: Journal of Cell Science. 127, p. 2460-2470 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. 2015
  92. Published

    Exploiting hydrophobicity for efficient production of transmembrane helices for structure determination by NMR spectroscopy

    Bugge, K. Ø., Steinocher, H., Brooks, A. J., Lindorff-Larsen, Kresten & Kragelund, Birthe Brandt, 2015, In: Analytical Chemistry. 87, 18, p. 9126–9131 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Functional characterization of a conserved archaeal viral operon revealing single-stranded DNA binding, annealing and nuclease activities

    Guo, Y., Kragelund, Birthe Brandt, White, M. F. & Peng, Xu, 2015, In: Journal of Molecular Biology. 427, 12, p. 2179-2191 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Intrinsically disordered cytoplasmic domains of two cytokine receptors mediate conserved interactions with membranes

    Haxholm, G. W., Nikolajsen, L. F., Olsen, Johan Gotthardt, Fredsted, J., Larsen, F. H., Goffin, V., Pedersen, Stine Helene Falsig, Brooks, A. J., Waters, M. J. & Kragelund, Birthe Brandt, 2015, In: Biochemical Journal. 468, 3, p. 495-506 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    A de novo designed monomeric, compact three helix bundle protein on a carbohydrate template

    Malik, L., Nygård, Jesper, Christensen, Niels Johan, Madsen, C. S., Rösner, Heike Ilona, Kragelund, Birthe Brandt, Høiberg-Nielsen, R., Streicher, W., Arleth, Lise, Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2015, In: ChemBioChem. 16, 13, p. 1905-1918 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Single site suppressors of a fission yeast temperature-sensitive mutant in cdc48 identified by whole genome sequencing

    Marinova, I. N., Engelbrecht, J., Ewald, A., Langholm, L. L., Holmberg, Christian, Kragelund, Birthe Brandt, Gordon, C., Nielsen, Olaf & Hartmann-Petersen, Rasmus, 2015, In: P L o S One. 10, 2, 15 p., e0117779.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    A two-step protein quality control pathway for a misfolded DJ-1 variant in fission yeast

    Mathiassen, S. G., Larsen, I. B., Poulsen, E. G., Madsen, C. T., Papaleo, E., Lindorff-Larsen, Kresten, Kragelund, Birthe Brandt, Nielsen, Michael Lund, Kriegenburg, F. & Hartmann-Petersen, Rasmus, 2015, In: The Journal of Biological Chemistry. 290, 34, p. 21141-21153 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Single-molecule folding mechanisms of the apo- and Mg2+-bound states of human neuronal calcium sensor-1

    Naqvi, M. M., Heiðarsson, P. O., Otazo, M. R., Mossa, A., Kragelund, Birthe Brandt & Cecconi, C., 2015, In: Biophysical Journal. 109, 1, p. 113-123 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Protein intrinsic disorder in Arabidopsis NAC transcription factors: transcriptional activation by ANAC013 and ANAC046 and their interactions with RCD1

    O'Shea, Charlotte, Jensen, M. K., Stender, E. G. P., Kragelund, Birthe Brandt, Willemoës, Martin & Skriver, Karen, 2015, In: Biochemical Journal. 465, 2, p. 281-294 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Globular and disordered-the non-identical twins in protein-protein interactions

    Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2015, In: Frontiers in Bioscience. 2, 6 p., 40.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    A residue quartet in the extracellular domain of the prolactin receptor selectively controls mitogen-activated protein kinase signaling

    Zhang, C., Nygaard, M., Haxholm, G. W., Boutillon, F., Bernadet, M., Hoos, S., England, P., Broutin, I., Kragelund, Birthe Brandt & Goffin, V., 2015, In: Journal of Biological Chemistry. 290, 19, p. 11890-11904 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    Residue 146 regulates prolactin receptor folding, basal activity and ligand-responsiveness: potential implications in breast tumorigenesis

    Zhang, C., Cherifi, I., Nygaard, M., Haxholm, G. W., Bogorad, R. L., Bernadet, M., England, P., Broutin, I., Kragelund, Birthe Brandt, Guidotti, J. & Goffin, V., 2015, In: Molecular and Cellular Endocrinology. 401, p. 173-188 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. 2016
  104. Published

    A combined computational and structural model of the full-length human prolactin receptor

    Bugge, K. Ø., Papaleo, E., Haxholm, G. W., Hopper, J. T. S., Robinson, C. V., Olsen, Johan Gotthardt, Lindorff-Larsen, Kresten & Kragelund, Birthe Brandt, 2016, In: Nature Communications. 7, 11 p., 11578.

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. Published

    Understanding single-pass transmembrane receptor signaling from a structural viewpoint—what are we missing?

    Bugge, K. Ø., Lindorff-Larsen, Kresten & Kragelund, Birthe Brandt, Dec 2016, In: The FEBS Journal. 283, 24, p. 4424-4451 28 p.

    Research output: Contribution to journalReviewResearchpeer-review

  106. Published

    The human Na+/H+ exchanger 1 is a membrane scaffold protein for extracellular signal-regulated kinase 2

    Hendus-Altenburger, R., Pedraz Cuesta, E., Olesen, C. W., Papaleo, E., Schnell, J. A., Hopper, J. T. S., Robinson, C. V., Pedersen, Stine Helene Falsig & Kragelund, Birthe Brandt, 2016, In: BMC Biology. 14, 17 p., 31.

    Research output: Contribution to journalJournal articleResearchpeer-review

  107. Published

    DSS1/Sem1, a multifunctional and intrinsically disordered protein

    Kragelund, Birthe Brandt, Schenstrøm, S. M., Rebula, C. A., Panse, V. G. & Hartmann-Petersen, Rasmus, 2016, In: Trends in Biochemical Sciences. 41, 5, p. 446-459 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  108. Published

    The Ku70/80 ring in Non-Homologous End-Joining: easy to slip on, hard to remove

    Kragelund, Birthe Brandt, Weterings, E., Hartmann-Petersen, Rasmus & Keijzers, G., 2016, In: Frontiers in Bioscience. 21, 3, p. 514-527 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  109. Published

    Prolactin signaling stimulates invasion via Na+/H+ exchanger NHE1 in T47D human breast cancer cells

    Pedraz Cuesta, E., Fredsted, J., Jensen, H. H., Bornebusch, A., Nejsum, L. N., Kragelund, Birthe Brandt & Pedersen, Stine Helene Falsig, 2016, In: Molecular Endocrinology. 30, 7, p. 693-708 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  110. Published

    An efficient arabinoxylan-debranching α-L-arabinofuranosidase of family GH62 from Aspergillus nidulans contains a secondary carbohydrate binding site

    Wilkens, C., Andersen, S., Petersen, B. O., Li, A., Busse-Wicher, M., Birch, J., Cockburn, D., Nakai, H., Christensen, H. E. M., Kragelund, Birthe Brandt, Dupree, P., McCleary, B., Hindsgaul, O., Abou Hachem, M. & Svensson, B., 2016, In: Applied Microbiology and Biotechnology. 100, 14, p. 6265-6277 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  111. 2017
  112. Published

    Deoxynucleoside salvage in fission yeast allows rescue of ribonucleotide reductase deficiency but not Spd1-mediated inhibition of replication

    Fleck, O., Fahnøe, Ulrik, Løvschal, K. V., Gasasira, M. U., Marinova, I. N., Kragelund, Birthe Brandt, Carr, A. M., Hartsuiker, E., Holmberg, Christian & Nielsen, Olaf, 25 Apr 2017, In: Genes. 8, 5, 14 p., 128.

    Research output: Contribution to journalJournal articleResearchpeer-review

  113. Published

    Single methyl groups can act as toggle switches to specify transmembrane protein-protein interactions

    He, L., Steinocher, H., Shelar, A., Cohen, E. B., Heim, E. N., Kragelund, Birthe Brandt, Grigoryan, G. & DiMaio, D., 4 Sep 2017, In: eLife. 6, 28 p., e27701.

    Research output: Contribution to journalJournal articleResearchpeer-review

  114. Published

    A phosphorylation-motif for tuneable helix stabilisation in intrinsically disordered proteins - Lessons from the sodium proton exchanger 1 (NHE1)

    Hendus-Altenburger, R., Lambrughi, M., Terkelsen, Thilde Bagger, Pedersen, Stine Helene Falsig, Papaleo, E., Lindorff-Larsen, Kresten & Kragelund, Birthe Brandt, Sep 2017, In: Cellular Signalling. 37, p. 40-51 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  115. Published

    Functions of intrinsic disorder in transmembrane proteins

    Kjærgaard, M. & Kragelund, Birthe Brandt, Sep 2017, In: Cellular and Molecular Life Sciences. 74, 17, p. 3205-3224 20 p.

    Research output: Contribution to journalReviewResearchpeer-review

  116. Published

    Choreography by Structural Disorder in Membrane Proteins

    Kragelund, Birthe Brandt, 2017, In: Biophysical Society. Annual Meeting. Abstracts. 112, 3, suppl. 1, p. 12A 1 p., 65-Subg.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  117. Published

    An efficient method for estimating the hydrodynamic radius of disordered protein conformations

    Nygaard, M., Kragelund, Birthe Brandt, Papaleo, E. & Lindorff-Larsen, Kresten, 8 Aug 2017, In: Biophysical Journal. 113, 3, p. 550-557 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  118. Published

    Structures and short linear motif of disordered transcription factor regions provide clues to the interactome of the cellular hub radical-induced cell death1

    O'Shea, Charlotte, Staby, L., Bendsen, S. K., Tidemand, Frederik Grønbæk, Redsted, A., Willemoës, Martin, Kragelund, Birthe Brandt & Skriver, Karen, 13 Jan 2017, In: Journal of Biological Chemistry. 292, 2, p. 512-527 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  119. Published

    Behaviour of intrinsically disordered proteins in protein-protein complexes with an emphasis on fuzziness

    Olsen, Johan Gotthardt, Teilum, Kaare & Kragelund, Birthe Brandt, Sep 2017, In: Cellular and Molecular Life Sciences. 74, 17, p. 3175-3183 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  120. Published

    Cold denaturation of the HIV-1 protease monomer

    Rösner, Heike Ilona, Caldarini, M., Prestel, Andreas, Vanoni, M. A., Broglia, R. A., Aliverti, A., Tiana, G. & Kragelund, Birthe Brandt, 7 Feb 2017, In: Biochemistry. 56, 8, p. 1029-1032 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  121. Published

    Eukaryotic transcription factors: paradigms of protein intrinsic disorder

    Staby, L., O'Shea, Charlotte, Willemoës, Martin, Theisen, F., Kragelund, Birthe Brandt & Skriver, Karen, 12 Jul 2017, In: Biochemical Journal. 474, 15, p. 2509-2532 24 p.

    Research output: Contribution to journalReviewResearchpeer-review

  122. Published

    SLiMming the fuzz in gene-regulating interactomes

    Staby, L., O'Shea, Charlotte, Kragelund, Birthe Brandt & Skriver, Karen, 7 Nov 2017, 1 p.

    Research output: Other contributionNet publication - Internet publicationResearch

  123. Published

    Class I Cytokine Receptors: Towards the Inside

    Steinocher, H., Bugge, K. Ø., Nikolajsen, L. F., Lindorff-Larsen, Kresten, Brooks, A. & Kragelund, Birthe Brandt, 2017, In: Biophysical Society. Annual Meeting. Abstracts. 112, 3. Suppl. 1, p. 171A 1 p., 845-Plat.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

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