Birthe Brandt Kragelund
Professor
Biomolecular Sciences
Ole Maaløes Vej 5
2200 København N.
- 1993
- Published
Threedimensional structure of the complex acyl-coenzyme, A binding protein and palmitoyl-coenzyme A
Kragelund, Birthe Brandt, Andersen, K. V., Madsen, J. C., Knudsen, J. & Poulsen, F., 1993, In: J. Mol. Biol.. 230, p. 1260-1277Research output: Contribution to journal › Journal article › Research › peer-review
- 1995
- Published
Folding of a four-helix bundle. Studies of acyl-coenzyme A binding protein
Kragelund, Birthe Brandt, Robinson, C. R., Knudsen, J., Dobson, C. M. & Poulsen, F., 1995, In: Biochemistry. 34, p. 7217-7224Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Local perturbations by ligand binding on hydrogen exchange kinetics in a four-helix bundle protein, acyl-coenzyme A binding protein (ACBP)
Kragelund, Birthe Brandt, Knudsen, J. & Poulsen, F., 1995, In: J. Mol. Biol.. 250, p. 695-706Research output: Contribution to journal › Journal article › Research › peer-review
- 1996
- Published
Thermodynamics of ligand binding to acyl-coenzyme, A binding protein studied by titration calometry
Færgeman, N. J., Sigurskjold, B. W., Kragelund, Birthe Brandt, Andersen, K. V. & Knudsen, J., 1996, In: Biochemistry. 35, p. 14118-14126Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fast and one-step folding of closely and distantly related homologous proteins of a four-helix bundle family
Kragelund, Birthe Brandt, Højrup, P., Jensen, M. S., Schjerling, C. K., Juul, E., Knudsen, J. & Poulsen, F., 1996, In: J. Mol. Biol.. 256, p. 187-200Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probing the nature of non-covalent interactions by mass spectrometry. A study of protein-CoA ligand interactions and assembly
Robinson, C. R., Chung, E. W., Kragelund, Birthe Brandt, Knudsen, J., Aplin, R. T., Poulsen, F. & Dobson, C. M., 1996, In: J. Amer. Chem.. 118, p. 8646-8653Research output: Contribution to journal › Journal article › Research › peer-review
- 1997
- Published
Structure of lipid-transfer protein complexed with palmitoyl-CoA. A hydrophobic binding site expandable to fit both large and small lipid-like ligands
Lerche, M. H., Kragelund, Birthe Brandt, Bech, L. & Poulsen, F., 1997, In: Structure. 5, p. 291-306Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
Hydrophobic core substitutions in calbindin D9k: effects on Ca2+ binding and dissociation
Kragelund, Birthe Brandt, Jönsson, M., Bifulco, G., Chazin, W. J., Nilsson, H., Finn, B. E. & Linse, S., 23 Jun 1998, In: Biochemistry. 37, 25, p. 8926-37 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mapping the lifetimes of local opening events in a native state protein
Kragelund, Birthe Brandt, Heinemann, B., Knudsen, J. & Poulsen, F., 1998, In: Protein Sci.. 7, p. 2237-2248Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
- Published
Acyl-coenzyme A binding protein (ACBP)
Kragelund, Birthe Brandt, Knudsen, J. & Poulsen, F. M., 23 Nov 1999, In: B B A - Reviews on Cancer. 1441, 2-3, p. 150-61 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
The formation of a native-like structure containing eight conserved hydrophobic residues is rate limiting in two-state protein folding of ACBP
Kragelund, Birthe Brandt, Osmark, P., Neergaard, T. B., Schiødt, J., Kristiansen, K., Knudsen, J. & Poulsen, F., 1999, In: Nature Structural and Molecular Biology. 6, 6, p. 594-601Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
- Published
1H, 13C, and 15N assignments of un-myristoylated Ca2+-frequenin, a synaptic efficacy modulator
Kragelund, Birthe Brandt, Hauenschild, A., Carlström, G., Pongs, O. & Finn, B. E., Jan 2000, In: Journal of Biomolecular N M R. 16, 1, p. 85-6 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation of hydrogen bonds precedes the rate-limiting formation of persistent structure in the folding of ACBP
Teilum, Kaare, Kragelund, Birthe Brandt, Knudsen, J. & Poulsen, F. M., 2000, In: Journal of Molecular Biology. 301, 5, p. 1307-14 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
Early kinetic intermediate in the folding of acyl-CoA binding protein detected by fluorescence labeling and ultrarapid mixing
Teilum, Kaare, Maki, K., Kragelund, Birthe Brandt, Poulsen, F. M. & Roder, H., 2002, In: Proceedings of the National Academy of Science of the United States of America. 99, 15, p. 9807-12 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transient structure formation in unfolded acyl-coenzyme A-binding protein observed by site-directed spin labelling
Teilum, Kaare, Kragelund, Birthe Brandt & Poulsen, F. M., 2002, In: Journal of Molecular Biology. 324, 2, p. 349-57 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transient intermediary states with high and low folding probabilities in the apparent two-state folding equilibrium of ACBP at low pH
Thomsen, J. K., Kragelund, Birthe Brandt, Teilum, Kaare, Knudsen, J. & Poulsen, F. M., 2002, In: Journal of Molecular Biology. 318, 3, p. 805-14 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fluorescently labelled bovine acyl-CoA-binding protein acting as an acyl-CoA sensor: interaction with CoA and acyl-CoA esters and its use in measuring free acyl-CoA esters and non-esterified fatty acids
Wadum, M. C., Villadsen, J. K., Feddersen, S., Moller, R. S., Neergaard, T. B., Kragelund, Birthe Brandt, Hojrup, P., Faergeman, N. J. & Knudsen, J., 2002, In: Biochemical Journal. 365, p. 165-172 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
Universitetsstuderendes tilgang til eksperimentelt udstyr - kønslige og faglige aspekter
Bruun, G. M., Kragelund, Birthe Brandt & Oddershede, L. B., 2003, In: Center for Naturfagenes Didaktiks Tidsskriftserie. 9, p. .Research output: Contribution to journal › Journal article › Research
- Published
Universitetsstuderendes tilgang til eksperimentelt udstyr - faglige og kønslige aspekter
Bruun, G. M., Kragelund, Birthe Brandt & Oddershede, L. B., 2003, Natureveidenskabs didaktik. Museum Tusculanum, Vol. 9. p. 1-37Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- 2004
- Published
Structure and biochemical function of a prototypical Arabidopsis U-box domain
Andersen, P., Kragelund, Birthe Brandt, Olsen, A. N., Larsen, F. H., Chua, N., Poulsen, F. M. & Skriver, Karen, 2004, In: Journal of Biological Chemistry. 279, 38, p. 40053-40061 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Reversible Dimerization of Acid-Denatured ACBP Controlled by Helix A4
Fieber, W., Kragelund, Birthe Brandt, Meldal, Morten Peter & Poulsen, F. M., 2005, In: Biochemistry. 44, 5, p. 1375-1384Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein folding: Defining a standard set of experimental conditions and a preliminary kinetic data set of two-state proteins
Maxwell, K. L., Wildes, D., Zarrine-Afsar, A., Rivos, M. A. D. L. R., Brown, A. G., Friel, C. T., Hedberg, L., Horng, J-C., Bona, D., Miller, E. J., Vallée-Bélisle, A., Main, E. R. G., Bemporad, F., Qiu, L., Teilum, K., Vu, N-D., Edwards, A. M., Ruczinski, I., Poulsen, F. M., Kragelund, B. B. & 14 others, , 2005, In: Protein Science. 14, 3, p. 602-616Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hydroxylation of the Herbicide Isoproturon by Fungi Isolated from Agricultural soil
Rønhede, S., Jensen, B., Rosendahl, Søren, Kragelund, Birthe Brandt, Juhler, R. K. & Aamand, J., 2005, In: Applied and Environmental Microbiology. 71, 12, p. 7927-7932Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Application of Hydrogen Exchange Kinetics to Studies of Protein Folding
Teilum, Kaare, Kragelund, Birthe Brandt & Poulsen, F. M., 2005, Protein Folding Handbook. Buchner, J. & Kiefhaber, T. (eds.). Weinheim: Wiley-VCH, p. 634-672Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Different secondary structure elements as scaffolds for protein folding transition states of two homologous four-helix bundles
Teilum, Kaare, Thormann, T., Caterer, N. R., Poulsen, H. I., Jensen, P. H., Knudsen, J., Kragelund, Birthe Brandt & Poulsen, F. M., 2005, In: Proteins - Structure Function and Bioinformatics. 59, 1, p. 80-90Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solution structure of human prolactin
Teilum, Kaare, Hoch, J. C., Goffin, V., Kinet, S., Martial, J. A. & Kragelund, Birthe Brandt, 2005, In: Journal of Molecular Biology. 351, 4, p. 810-23 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
A loop of coagulation factor VIIa influencing macromolecular substrate specificity.
Bjelke, J. R., Persson, E., Rasmussen, H. B., Kragelund, Birthe Brandt & Olsen, O. H., 2006, In: FEBS Letters. 581, 1, p. 71-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Binding site structure of one LRP-RAP complex: implications for a common ligand-receptor binding motif.
Jensen, G. A., Andersen, O. M., Bonvin, A. M. J. J., Bjerrum-Bohr, I., Etzerodt, M., Thøgersen, H. C., O'Shea, Charlotte, Poulsen, F. M. & Kragelund, Birthe Brandt, 2006, In: Journal of Molecular Biology. 362, 4, p. 700-16 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Structure of the human beta-ketoacyl [ACP] synthase from the mitochondrial type II fatty acid synthase
Christensen, Caspar Elo, Kragelund, Birthe Brandt, Von Wettstein-Knowles, P. & Henriksen, A., Feb 2007, In: Protein Science. 16, 2, p. 261-272Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acyl-CoA binding proteins; structural and functional conservation over 2000 MYA.
Faergeman, N. J., Wadum, M., Feddersen, S., Burton, M., Kragelund, Birthe Brandt & Knudsen, J., 2007, In: Molecular and Cellular Biochemistry. 299, 1-2, p. 55-65 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural and thermodynamic bases for the design of pure prolactin receptor antagonists: X-ray structure of Del1-9-G129R-hPRL.
Jomain, J., Tallet, E., Broutin, I., Hoos, S., van Agthoven, J., Ducruix, A., Kelly, P. A., Kragelund, Birthe Brandt, England, P. & Goffin, V., 2007, In: Journal of Biological Chemistry. 282, 45, p. 33118-31 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Engineering the substrate and inhibitor specificities of human coagulation Factor VIIa.
Larsen, K. S., Østergaard, H., Bjelke, J. R., Olsen, O. H., Rasmussen, H. B., Christensen, L., Kragelund, Birthe Brandt & Stennicke, H. R., 2007, In: Biochemical Journal. 405, 3, p. 429-38 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-activity study of the antibacterial peptide fallaxin
Søndergaard, S. L., Frimodt-Møller, N., Kragelund, Birthe Brandt & Hansen, Paul Robert, 2007, In: Protein Science. 16, 9, p. 1969-1976 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Mechanism of the Ca2+-induced enhancement of the intrinsic factor VIIa activity
Bjelke, J. R., Olsen, O. H., Fodje, M., Svensson, L. A., Bang, S., Bolt, G., Kragelund, Birthe Brandt & Persson, E., 2008, In: Journal of Biological Chemistry. 283, 38, p. 25863-70 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The intrinsically disordered RNR inhibitor Sml1 is a dynamic dimer
Danielsson, J., Liljedahl, L., Ba´ra´ny-Wallje, E., Sønderby, P., Kristensen, L. H., Martinez-Yamout, M. A., Dyson, H. J., Wright, P. E., Poulsen, F. M., Ma¨ler, L., Gra¨slund, A. & Kragelund, Birthe Brandt, 2008, In: Biochemistry. 47, 50, p. 13428-13437 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acyl-CoA-binding protein (ACBP) localizes to the endoplasmic reticulum and Golgi in a ligand-dependent manner in mammalian cells.
Hansen, J. S., Færgeman, N. J., Kragelund, Birthe Brandt & Knudsen, J., 2008, In: Biochemical Journal. 410, 3, p. 463-472 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phosphate Selective Uranyl Photo-Affinity Cleavage of Proteins. Determination of Phosphorylation Sites.
Kristensen, L. H., Nielsen, Peter E., Jørgensen, C. I., Kragelund, Birthe Brandt & Møllegaard, Niels Erik, 2008, In: ChemBioChem. 9, 15, p. 2377-81 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Metabolites of the phenylurea herbicides chlorotoluron, diuron, isoproturonand linuron produced by the soil fungus Mortierella sp.
Badawi, N., Rønhede, S., Olsson, S., Kragelund, Birthe Brandt, Johnsen, A. H., Jacobsen, O. S. & Aamand, J., 2009, In: Environmental Pollution. 157, 10, p. 2806-2812 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure of the Mature Streptococcal Cysteine Protease Exotoxin mSpeB in Its Active Dimeric Form
Olsen, Johan Gotthardt, Dagil, Robert, Niclasen, L. M., Sørensen, O. E. & Kragelund, Birthe Brandt, 2009, In: Journal of Molecular Biology. 393, 3, p. 693-703 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional aspects of protein flexibility
Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2009, In: Cellular and Molecular Life Sciences. 66, 14, p. 2231-47 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Crystal structure of an affinity-matured prolactin complexed to its dimerized receptor reveals the topology of hormone binding site 2.
Broutin, I., Jomain, J., Tallet, E., Van Agthoven, J., Raynal, B., Hoos, S., Kragelund, Birthe Brandt, Kelly, P., Ducroix, A., England, P. & Goffin, V., 2010, In: Journal of Biological Chemistry. 285, 11, p. 8422-8433 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Temperature-dependent structural changes in intrinsically disordered proteins: formation of alpha-helices or loss of polyproline II?
Kjærgaard, M., Nørholm, A., Hendus-Altenburger, R., Pedersen, Stine Helene Falsig, Poulsen, F. M. & Kragelund, Birthe Brandt, 1 Aug 2010, In: Protein Science. 19, 8, p. 1555-64 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of ribonucleotide reductase by Spd1 involves multiple mechanisms
Nestoras, K., Mohammed, A. H., Schreurs, A., Fleck, O., Watson, A. T., Poitelea, M., O'Shea, Charlotte, Chahwan, C., Holmberg, Christian, Kragelund, Birthe Brandt, Nielsen, Olaf, Osborne, M., Carr, A. M. & Liu, C., 1 Jun 2010, In: Genes & Development. 24, 11, p. 1145-1159 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Far UV CD study of de novo designed antimicrobial coiled coils upon interaction with model membranes
Søndergaard, S. L., Kragelund, Birthe Brandt, Thulstrup, Peter Waaben, Brahm, Jesper, Siegumfeldt, Henrik, Frimodt-Møller, N. & Hansen, Paul Robert, 2010, In: Journal of Peptide Science. S2Research output: Contribution to journal › Conference abstract in journal › Research
- 2011
- Published
Development of prolactin receptor antagonists with reduced pH-dependence of receptor binding.
Hansen, M. J. K., Olsen, Johan Gotthardt, Bernichtein, S., O'Shea, Charlotte, Sigurskjold, B. W., Goffin, V. & Kragelund, Birthe Brandt, 2011, In: Journal of Molecular Recognition. 24, 4, p. 533-547 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Senescence-associated barley NAC (NAM, ATAF1,2, CUC) transcription factor interacts with radical-induced cell death 1 through a disordered regulatory domain
Kjaersgaard, T., Jensen, M. K., Christiansen, M. W., Gregersen, P. L., Kragelund, Birthe Brandt & Skriver, Karen, 2011, In: Journal of Biological Chemistry. 286, 41, p. 35418-29 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Streptococcal pyogenic exotoxin B (SpeB) boosts the contact system via binding of a-1 antitrypsin
Meinert Niclasen, L., Olsen, Johan Gotthardt, Dagil, Robert, Qing, Z., Sørensen, O. E. & Kragelund, Birthe Brandt, 2011, In: Biochemical Journal. 434, 1, p. 123-32 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Intracellular Distal Tail of the Na+/H+ Exchanger NHE1 Is Intrinsically Disordered: Implications for NHE1 Trafficking
Nørholm, A., Hendus-Altenburger, R., Bjerre, G., Kjærgaard, M., Pedersen, Stine Helene Falsig & Kragelund, Birthe Brandt, 2011, In: Biochemistry. 50, 17, p. 3469-80 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein stability, flexibility and function
Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2011, In: B B A - Proteins and Proteomics. 1814, 8, p. 969-76 8 p.Research output: Contribution to journal › Review › Research › peer-review
- 2012
- Published
The WSXWS motif in cytokine receptors is a molecular switch involved in receptor activation: insight from structures of the prolactin receptor
Dagil, Robert, Knudsen, M. J., Olsen, Johan Gotthardt, O'Shea, Charlotte, Franzmann, M., Goffin, V., Teilum, Kaare, Breinholt, J. & Kragelund, Birthe Brandt, 2012, In: Structure. 20, 2, p. 270-282 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
β-Microseminoprotein endows post coital seminal plasma with potent candidacidal activity by a calcium- and pH-dependent mechanism.
Edström Hägerwall, A., Rydengård, V., Fernlund, P., Mörgelin, M., Baumgarten, M., Cole, A. M., Malmsten, M., Kragelund, Birthe Brandt & Sørensen, O. E., 2012, In: P L o S Pathogens. 8, 4, p. 1-12 12 p., e1002625.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A highly compliant protein native state with a spontaneous-like mechanical unfolding pathway
Heiðarsson, P. O., Valpapuram, I., Camilloni, C., Imparato, A., Tiana, G., Poulsen, F. M., Kragelund, Birthe Brandt & Cecconi, C., 2012, In: Journal of the American Chemical Society. 134, 41, p. 17068-17075 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The C-terminal tail of human neuronal calcium sensor 1 regulates the conformational stability of the Ca2+-activated state
Heiðarsson, P. O., Bjerrum-Bohr, I. J., Jensen, G. A., Pongs, O., Finn, B. E., Poulsen, F. M. & Kragelund, Birthe Brandt, 2012, In: Journal of Molecular Biology. 417, 1-2, p. 51-64 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analyzing temperature-induced transitions in disordered proteins by NMR spectroscopy and secondary chemical shift analyses
Kjærgaard, M., Poulsen, F. M. & Kragelund, Birthe Brandt, 2012, Intrinsically disordered protein analysis: methods and experimental tools. Uversky, V. N. & Dunker, A. K. (eds.). Springer, Vol. 2. p. 249-256 8 p. (Methods in Molecular Biology, Vol. 896).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Temperature-induced transitions in disordered proteins probed by NMR spectroscopy
Kjærgaard, M., Poulsen, F. M. & Kragelund, Birthe Brandt, 2012, Intrinsically disordered protein analysis: methods and experimental tools. Uversky, V. N. & Dunker, A. K. (eds.). Springer, Vol. 2. p. 233-247 15 p. (Methods in Molecular Biology, Vol. 896).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Order by disorder in plant signaling
Kragelund, Birthe Brandt, Jensen, M. K. & Skriver, Karen, 2012, In: Trends in Plant Science. 17, 11, p. 625-632 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure and Dynamic Properties of Membrane Proteins using NMR
Rösner, Heike Ilona & Kragelund, Birthe Brandt, 2012, In: Comprehensive Physiology. 2, 2, p. 1491-1539 49 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
New horizons for lipoprotein receptors: communication by β-propellers
Andersen, O. M., Dagil, Robert & Kragelund, Birthe Brandt, 2013, In: Journal of Lipid Research. 54, p. 2763-2774 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gentamicin binds to the megalin receptor as a competitive inhibitor using the common ligand binding motif of complement type repeats: insight from the nmr structure of the 10th complement type repeat domain alone and in complex with gentamicin
Dagil, Robert, O'Shea, Charlotte, Nykjær, A., Bonvin, A. M. J. J. & Kragelund, Birthe Brandt, 2013, In: The Journal of Biological Chemistry. 288, 6, p. 4424-35 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Strains of the soil fungus Mortierella show different degradation potentials for the phenylurea herbicide diuron
Ellegaard-Jensen, L., Aamand, J., Kragelund, Birthe Brandt, Johnsen, A. H. & Rosendahl, Søren, 2013, In: Biodegradation. 24, 6, p. 765-774 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single-molecule folding mechanism of an EF-hand neuronal calcium sensor
Heiðarsson, P. O., Otazo, M. R., Bellucci, L., Mossa, A., Imparato, A., Paci, E., Corni, S., Felice, R. D., Kragelund, Birthe Brandt & Cecconi, C., 2013, In: Structure. 21, 10, p. 1812-1821 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solution properties of the archaeal CRISPR DNA repeat-binding homeodomain protein Cbp2
Kenchappa, C., Heiðarsson, P. O., Kragelund, Birthe Brandt, Garrett, Roger Antony & Poulsen, F., 2013, In: Nucleic Acids Research. 41, 5, p. 3424-3435 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The transcriptional repressor domain of Gli3 is intrinsically disordered
Tsanev, R., Vanatalu, K., Jarvet, J., Tanner, R., Laur, K., Tiigimägi, P., Kragelund, Birthe Brandt, Østerlund, T. & Kogerman, P., 2013, In: PLoS ONE. 8, 10, 9 p., e76972.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Direct single-molecule observation of calcium-dependent misfolding in human neuronal calcium sensor-1
Heiðarsson, P. O., Naqvi, M. M., Otazo, M. R., Mossa, A., Kragelund, Birthe Brandt & Cecconi, C., 2014, In: Proceedings of the National Academy of Sciences U.S.A.. 111, 36, p. 13069-13074 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural dynamics and regulation of the mammalian SLC9A family of Na+/H+ exchangers
Hendus-Altenburger, R., Kragelund, Birthe Brandt & Pedersen, Stine Helene Falsig, 2014, Current Topics in Membranes: Exchangers. Bevensee, M. O. (ed.). Elsevier, Vol. 73. p. 69-148 80 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Who climbs the tryptophan ladder? On the structure and function of the WSXWS motif in cytokine receptors and thrombospondin repeats
Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2014, In: Cytokine & Growth Factor Reviews. 25, 3, p. 337-341 5 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Exploring the minimally frustrated energy landscape of unfolded ACBP
Ozenne, V., Noel, J. K., Heiðarsson, P. O., Brander, S., Poulsen, F. M., Jensen, M. R., Kragelund, Birthe Brandt, Blackledge, M. & Danielsson, J. A., 2014, In: Journal of Molecular Biology. 426, 3, p. 722-734 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dss1 is a 26S proteasome ubiquitin receptor
Paraskevopoulos, K., Kriegenburg, F., Tatham, M. H., Rösner, Heike Ilona, Medina, B., Larsen, I. B., Brandstrup, R., Hardwick, K. G., Hay, R. T., Kragelund, Birthe Brandt, Hartmann-Petersen, Rasmus & Gordon, C., 2014, In: Molecular Cell. 56, 3, p. 453-461 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CECAM workshop on intrinsically disordered proteins
Rösner, Heike Ilona, Papaleo, E., Haxholm, G. W., Best, R. B., Kragelund, Birthe Brandt & Lindorff-Larsen, Kresten, 2014, In: Intrinsically Disordered Proteins. 2, 1, p. 1-5 5 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Spd2 assists Spd1 in the modulation of ribonucleotide reductase architecture but does not regulate deoxynucleotide pools
Vejrup-Hansen, R., Fleck, O., Landvad, K., Fahnøe, Ulrik, Broendum, S. S., Schreurs, A., Kragelund, Birthe Brandt, Carr, A. M., Holmberg, Christian & Nielsen, Olaf, 2014, In: Journal of Cell Science. 127, p. 2460-2470 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Exploiting hydrophobicity for efficient production of transmembrane helices for structure determination by NMR spectroscopy
Bugge, K. Ø., Steinocher, H., Brooks, A. J., Lindorff-Larsen, Kresten & Kragelund, Birthe Brandt, 2015, In: Analytical Chemistry. 87, 18, p. 9126–9131 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional characterization of a conserved archaeal viral operon revealing single-stranded DNA binding, annealing and nuclease activities
Guo, Y., Kragelund, Birthe Brandt, White, M. F. & Peng, Xu, 2015, In: Journal of Molecular Biology. 427, 12, p. 2179-2191 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intrinsically disordered cytoplasmic domains of two cytokine receptors mediate conserved interactions with membranes
Haxholm, G. W., Nikolajsen, L. F., Olsen, Johan Gotthardt, Fredsted, J., Larsen, F. H., Goffin, V., Pedersen, Stine Helene Falsig, Brooks, A. J., Waters, M. J. & Kragelund, Birthe Brandt, 2015, In: Biochemical Journal. 468, 3, p. 495-506 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A de novo designed monomeric, compact three helix bundle protein on a carbohydrate template
Malik, L., Nygård, Jesper, Christensen, Niels Johan, Madsen, C. S., Rösner, Heike Ilona, Kragelund, Birthe Brandt, Høiberg-Nielsen, R., Streicher, W., Arleth, Lise, Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2015, In: ChemBioChem. 16, 13, p. 1905-1918 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single site suppressors of a fission yeast temperature-sensitive mutant in cdc48 identified by whole genome sequencing
Marinova, I. N., Engelbrecht, J., Ewald, A., Langholm, L. L., Holmberg, Christian, Kragelund, Birthe Brandt, Gordon, C., Nielsen, Olaf & Hartmann-Petersen, Rasmus, 2015, In: P L o S One. 10, 2, 15 p., e0117779.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A two-step protein quality control pathway for a misfolded DJ-1 variant in fission yeast
Mathiassen, S. G., Larsen, I. B., Poulsen, E. G., Madsen, C. T., Papaleo, E., Lindorff-Larsen, Kresten, Kragelund, Birthe Brandt, Nielsen, Michael Lund, Kriegenburg, F. & Hartmann-Petersen, Rasmus, 2015, In: The Journal of Biological Chemistry. 290, 34, p. 21141-21153 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single-molecule folding mechanisms of the apo- and Mg2+-bound states of human neuronal calcium sensor-1
Naqvi, M. M., Heiðarsson, P. O., Otazo, M. R., Mossa, A., Kragelund, Birthe Brandt & Cecconi, C., 2015, In: Biophysical Journal. 109, 1, p. 113-123 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein intrinsic disorder in Arabidopsis NAC transcription factors: transcriptional activation by ANAC013 and ANAC046 and their interactions with RCD1
O'Shea, Charlotte, Jensen, M. K., Stender, E. G. P., Kragelund, Birthe Brandt, Willemoës, Martin & Skriver, Karen, 2015, In: Biochemical Journal. 465, 2, p. 281-294 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Globular and disordered-the non-identical twins in protein-protein interactions
Teilum, Kaare, Olsen, Johan Gotthardt & Kragelund, Birthe Brandt, 2015, In: Frontiers in Bioscience. 2, 6 p., 40.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A residue quartet in the extracellular domain of the prolactin receptor selectively controls mitogen-activated protein kinase signaling
Zhang, C., Nygaard, M., Haxholm, G. W., Boutillon, F., Bernadet, M., Hoos, S., England, P., Broutin, I., Kragelund, Birthe Brandt & Goffin, V., 2015, In: Journal of Biological Chemistry. 290, 19, p. 11890-11904 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Residue 146 regulates prolactin receptor folding, basal activity and ligand-responsiveness: potential implications in breast tumorigenesis
Zhang, C., Cherifi, I., Nygaard, M., Haxholm, G. W., Bogorad, R. L., Bernadet, M., England, P., Broutin, I., Kragelund, Birthe Brandt, Guidotti, J. & Goffin, V., 2015, In: Molecular and Cellular Endocrinology. 401, p. 173-188 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
A combined computational and structural model of the full-length human prolactin receptor
Bugge, K. Ø., Papaleo, E., Haxholm, G. W., Hopper, J. T. S., Robinson, C. V., Olsen, Johan Gotthardt, Lindorff-Larsen, Kresten & Kragelund, Birthe Brandt, 2016, In: Nature Communications. 7, 11 p., 11578.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Understanding single-pass transmembrane receptor signaling from a structural viewpoint—what are we missing?
Bugge, K. Ø., Lindorff-Larsen, Kresten & Kragelund, Birthe Brandt, Dec 2016, In: The FEBS Journal. 283, 24, p. 4424-4451 28 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The human Na+/H+ exchanger 1 is a membrane scaffold protein for extracellular signal-regulated kinase 2
Hendus-Altenburger, R., Pedraz Cuesta, E., Olesen, C. W., Papaleo, E., Schnell, J. A., Hopper, J. T. S., Robinson, C. V., Pedersen, Stine Helene Falsig & Kragelund, Birthe Brandt, 2016, In: BMC Biology. 14, 17 p., 31.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DSS1/Sem1, a multifunctional and intrinsically disordered protein
Kragelund, Birthe Brandt, Schenstrøm, S. M., Rebula, C. A., Panse, V. G. & Hartmann-Petersen, Rasmus, 2016, In: Trends in Biochemical Sciences. 41, 5, p. 446-459 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Ku70/80 ring in Non-Homologous End-Joining: easy to slip on, hard to remove
Kragelund, Birthe Brandt, Weterings, E., Hartmann-Petersen, Rasmus & Keijzers, G., 2016, In: Frontiers in Bioscience. 21, 3, p. 514-527 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prolactin signaling stimulates invasion via Na+/H+ exchanger NHE1 in T47D human breast cancer cells
Pedraz Cuesta, E., Fredsted, J., Jensen, H. H., Bornebusch, A., Nejsum, L. N., Kragelund, Birthe Brandt & Pedersen, Stine Helene Falsig, 2016, In: Molecular Endocrinology. 30, 7, p. 693-708 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An efficient arabinoxylan-debranching α-L-arabinofuranosidase of family GH62 from Aspergillus nidulans contains a secondary carbohydrate binding site
Wilkens, C., Andersen, S., Petersen, B. O., Li, A., Busse-Wicher, M., Birch, J., Cockburn, D., Nakai, H., Christensen, H. E. M., Kragelund, Birthe Brandt, Dupree, P., McCleary, B., Hindsgaul, O., Abou Hachem, M. & Svensson, B., 2016, In: Applied Microbiology and Biotechnology. 100, 14, p. 6265-6277 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Deoxynucleoside salvage in fission yeast allows rescue of ribonucleotide reductase deficiency but not Spd1-mediated inhibition of replication
Fleck, O., Fahnøe, Ulrik, Løvschal, K. V., Gasasira, M. U., Marinova, I. N., Kragelund, Birthe Brandt, Carr, A. M., Hartsuiker, E., Holmberg, Christian & Nielsen, Olaf, 25 Apr 2017, In: Genes. 8, 5, 14 p., 128.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single methyl groups can act as toggle switches to specify transmembrane protein-protein interactions
He, L., Steinocher, H., Shelar, A., Cohen, E. B., Heim, E. N., Kragelund, Birthe Brandt, Grigoryan, G. & DiMaio, D., 4 Sep 2017, In: eLife. 6, 28 p., e27701.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A phosphorylation-motif for tuneable helix stabilisation in intrinsically disordered proteins - Lessons from the sodium proton exchanger 1 (NHE1)
Hendus-Altenburger, R., Lambrughi, M., Terkelsen, Thilde Bagger, Pedersen, Stine Helene Falsig, Papaleo, E., Lindorff-Larsen, Kresten & Kragelund, Birthe Brandt, Sep 2017, In: Cellular Signalling. 37, p. 40-51 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functions of intrinsic disorder in transmembrane proteins
Kjærgaard, M. & Kragelund, Birthe Brandt, Sep 2017, In: Cellular and Molecular Life Sciences. 74, 17, p. 3205-3224 20 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Choreography by Structural Disorder in Membrane Proteins
Kragelund, Birthe Brandt, 2017, In: Biophysical Society. Annual Meeting. Abstracts. 112, 3, suppl. 1, p. 12A 1 p., 65-Subg.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
An efficient method for estimating the hydrodynamic radius of disordered protein conformations
Nygaard, M., Kragelund, Birthe Brandt, Papaleo, E. & Lindorff-Larsen, Kresten, 8 Aug 2017, In: Biophysical Journal. 113, 3, p. 550-557 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structures and short linear motif of disordered transcription factor regions provide clues to the interactome of the cellular hub radical-induced cell death1
O'Shea, Charlotte, Staby, L., Bendsen, S. K., Tidemand, Frederik Grønbæk, Redsted, A., Willemoës, Martin, Kragelund, Birthe Brandt & Skriver, Karen, 13 Jan 2017, In: Journal of Biological Chemistry. 292, 2, p. 512-527 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Behaviour of intrinsically disordered proteins in protein-protein complexes with an emphasis on fuzziness
Olsen, Johan Gotthardt, Teilum, Kaare & Kragelund, Birthe Brandt, Sep 2017, In: Cellular and Molecular Life Sciences. 74, 17, p. 3175-3183 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Cold denaturation of the HIV-1 protease monomer
Rösner, Heike Ilona, Caldarini, M., Prestel, Andreas, Vanoni, M. A., Broglia, R. A., Aliverti, A., Tiana, G. & Kragelund, Birthe Brandt, 7 Feb 2017, In: Biochemistry. 56, 8, p. 1029-1032 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Eukaryotic transcription factors: paradigms of protein intrinsic disorder
Staby, L., O'Shea, Charlotte, Willemoës, Martin, Theisen, F., Kragelund, Birthe Brandt & Skriver, Karen, 12 Jul 2017, In: Biochemical Journal. 474, 15, p. 2509-2532 24 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
SLiMming the fuzz in gene-regulating interactomes
Staby, L., O'Shea, Charlotte, Kragelund, Birthe Brandt & Skriver, Karen, 7 Nov 2017, 1 p.Research output: Other contribution › Net publication - Internet publication › Research
- Published
Class I Cytokine Receptors: Towards the Inside
Steinocher, H., Bugge, K. Ø., Nikolajsen, L. F., Lindorff-Larsen, Kresten, Brooks, A. & Kragelund, Birthe Brandt, 2017, In: Biophysical Society. Annual Meeting. Abstracts. 112, 3. Suppl. 1, p. 171A 1 p., 845-Plat.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
ID: 9500
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Solution properties of the archaeal CRISPR DNA repeat-binding homeodomain protein Cbp2
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Single site suppressors of a fission yeast temperature-sensitive mutant in cdc48 identified by whole genome sequencing
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Dss1 is a 26S proteasome ubiquitin receptor
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