Arne Schousboe

Arne Schousboe

Professor, emeritus

ORCID: 0000-0001-9600-402X

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  1. Published

    (1S, 3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid (CPP-115), a potent gamma-aminobutyric acid aminotransferase inactivator for the treatment of cocaine addiction

    Pan, Y., Gerasimov, M. R., Kvist, T., Wellendorph, Petrine, Madsen, K. K., Pera, E., Lee, H., Schousboe, Arne, Chebib, M., Bräuner, Hans, Craft, C. M., Brodie, J. D., Schiffer, W. K., Dewey, S. L., Miller, S. R. & Silverman, R. B., 1 Jan 2012, In: Journal of Medicinal Chemistry. 55, 1, p. 357-366

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    13C NMR spectroscopy and mass spectrometry analysis of intermediary metabolism in cultured neural cells

    Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 18 Mar 2011, Cell Culture Techniques. Aschner, M., Sunol, C. & Bal-Price, A. (eds.). p. 403-415 13 p. (Neuromethods, Vol. 56).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  3. Published

    1H-cyclopentapyrimidine-2,4(1H,3H)-dione-related ionotropic glutamate receptors ligands. Structure-activity relationships and identification of potent and selective iGluR5 modulators

    Butini, S., Pickering, Darryl S, Morelli, E., Coccone, S. S., Trotta, F., De Angelis, M., Guarino, E., Fiorini, I., Campiani, G., Novellino, E., Schousboe, Arne, Christensen, J. K. & Gemma, S., 2008, In: Journal of Medicinal Chemistry. 51, 20, p. 6614-8

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    3H-D-aspartate release from cerebellar granule neurons is differentially regulated by glutamate- and K(+)-stimulation

    Belhage, B., Rehder, V., Hansen, Gert Helge, Kater, S. B. & Schousboe, Arne, 1992, In: Journal of Neuroscience Research. 33, 3, p. 436-44 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    40 year anniversary issue of neurochemical research

    Schousboe, Arne, 2016, In: Neurochemical Research. 41, 1-2, p. 1-2 2 p.

    Research output: Contribution to journal › Editorial › Research

  6. Published

    A Tribute to Mary C. McKenna: Glutamate as Energy Substrate and Neurotransmitter-Functional Interaction Between Neurons and Astrocytes

    Schousboe, Arne, Jan 2017, In: Neurochemical Research. 42, 1, p. 4-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    A functioning glycolysis is important for maintenance of glutamate transport in cultured astrocytes

    Schousboe, Arne, Sickmann, H. M., Bak, Lasse Kristoffer, Schousboe, I., Bouman, S. D. & Waagepetersen, Helle S., 2010, In: Journal of Neurochemistry. s1, p. 288-289

    Research output: Contribution to journal › Conference abstract in journal › Research

  8. Published

    A novel selective γ-aminobutyric acid transport inhibitor demonstrates a functional role for GABA transporter subtype GAT2/BGT-1 in the CNS

    Frølund, Bente, Clausen, Rasmus Prætorius, Larsson, O. M., Schousboe, Arne, Krogsgaard-Larsen, Povl & White, H. S., 2006, In: Neurochemistry International. 48, p. 637–642

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    A possible role of the non-GAT1 GABA transporters in transfer of GABA from GABAergic to glutamatergic neurons in mouse cerebellar neuronal cultures

    Suñol, C., Babot, Z., Cristòfol, R., Sonnewald, U., Waagepetersen, Helle S. & Schousboe, Arne, Sep 2010, In: Neurochemical Research. 35, 9, p. 1384-1390 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    A single glycine residue at the entrance to the first membrane-spanning domain of the γ-aminobutyric acid type a receptor β2 subunit affects allosteric sensitivity to GABA and anesthetics

    Carlson, B. X., Engblom, A. C., Kristiansen, Uffe, Schousboe, Arne & Olsen, R. W., 2000, In: Molecular Pharmacology. 57, 3, p. 474-484 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    A subconvulsive dose of kainate selectively compromises astrocytic metabolism in the mouse brain in vivo

    Walls, Anne Byriel, Eyjolfsson, E. M., Schousboe, Arne, Sonnewald, U. & Waagepetersen, Helle S., Aug 2014, In: Journal of Cerebral Blood Flow and Metabolism. 34, 8, p. 1340-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Accepted/In press

    A tribute to Leif Hertz: The historical context of his pioneering studies of the roles of astrocytes in brain energy metabolism, neurotransmission, cognitive functions, and pharmacology identifies important, unresolved topics for future studies

    Dienel, G. A., Schousboe, Arne, McKenna, M. C. & Rothman, D. L., 2023, (Accepted/In press) In: Journal of Neurochemistry.

    Research output: Contribution to journal › Review › Research › peer-review

  13. Published

    AMPA receptor mediated excitotoxicity in neocortical neurons is developmentally regulated and dependent upon receptor desensitization

    Jensen, J. B., Schousboe, Arne, Pickering, Darryl S & Pickering, Darryl S, 1998, In: Neurochemistry International. 32, 5-6, p. 505-13 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    AMPK Activation Affects Glutamate Metabolism in Astrocytes

    Voss, C. M., Pajęcka, K., Stridh, M. H., Nissen, J. D., Schousboe, Arne & Waagepetersen, Helle S., 7 Apr 2015, In: Neurochemical Research. 40, 12, p. 2431-2442 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Action of bicyclic isoxazole GABA analogues on GABA transporters and its relation to anticonvulsant activity

    Bolvig, T., Larsson, O. M., Pickering, Darryl S, Nelson, N., Falch, E., Krogsgaard-Larsen, Povl, Schousboe, Arne & Pickering, Darryl S, 1999, In: European Journal of Pharmacology. 375, 1-3, p. 367-74 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Actions of toxins on cerebral metabolism at cellular level

    Sonnewald, U., Syversen, T., Schousboe, Arne, Waagepetersen, Helle S. & Aschner, M., 2007, Handbook of Neurochemistry and Molecular Neurobiology: Brain Energetics. Integration of Molecular and Cellular Processes. Lajtha, A., Gibson, G. E. & Dienel, G. A. (eds.). 3rd. ed. ed. Berlin: Springer, Vol. 3. p. 569-585

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  17. Published

    Activity of the lactate-alanine shuttle is independent of glutamate-glutamine cycle activity in cerebellar neuronal-astrocytic cultures

    Bak, Lasse Kristoffer, Sickmann, H. M., Schousboe, Arne & Waagepetersen, Helle S., 4 Dec 2004, In: Journal of Neuroscience Research. 79, 1-2, p. 88-96 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Agonist discrimination between AMPA receptor subtypes

    Coquelle, T., Christensen, J. K., Banke, T. G., Madsen, U., Schousboe, Arne & Pickering, Darryl S, 2000, In: NeuroReport. 11, 12, p. 2643-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Amino acid neurotransmitter synthesis and removal

    Schousboe, Arne, Bak, Lasse Kristoffer, Madsen, K. K. & Waagepetersen, Helle S., 2013, Neuroglia. Kettenman, H. & Ransom, B. R. (eds.). 3. ed. Oxford: Oxford University Press, p. 443-456 14 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  20. Published

    Amino acids: Glutamate dehydrogenase: An anaplerotic enzyme in neurons and an energy producing enzyme in astrocytes

    Schousboe, Arne & Aldana, Blanca, 29 Jul 2021, Encyclopedia of Biological Chemistry: Third Edition. Elsevier, Vol. 1. p. 51-55 5 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  21. Published

    Among the branched-chain amino acids, only valine metabolism is up-regulated in astrocytes during glutamate exposure

    Bak, Lasse Kristoffer, Johansen, M. L., Schousboe, Arne & Waagepetersen, Helle S., 2007, In: Journal of Neuroscience Research. 86, p. 3465-3470

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Anaplerosis for Glutamate Synthesis in the Neonate and in Adulthood

    Brekke, E., Morken, T. S., Walls, Anne Byriel, Waagepetersen, Helle S., Schousboe, Arne & Sonnewald, U., 2016, The Glutamate/ GABA- Glutamine Cycle : Amino Acid Neurotransmitter Homeostasis. Springer, Vol. 13. p. 43-58 16 p. (Advances in Neurobiology, Vol. 13).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  23. Published

    Aspartate-glutamate homeostasis in cerebellar neurons changes when shifting from glucose to beta-hydroxybutyrate as substrate

    Lund, Trine Meldgaard, Clausen, M., Risa, Ø., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. s1, p. 291-291

    Research output: Contribution to journal › Conference abstract in journal › Research

  24. Published

    Aspects of astrocyte energy metabolism, amino acid neurotransmitter homoeostasis and metabolic compartmentation

    Kreft, M., Bak, Lasse Kristoffer, Waagepetersen, Helle S. & Schousboe, Arne, 2012, In: A S N Neuro. 4, 3, p. 187 199 p.

    Research output: Contribution to journal › Review › Research › peer-review

  25. Published

    Astrocyte energy and neurotransmitter metabolism in Alzheimer's disease: Integration of the glutamate/GABA-glutamine cycle

    Andersen, Jens Velde, Schousboe, Arne & Verkhratsky, A., 2022, In: Progress in Neurobiology. 217, 24 p., 102331.

    Research output: Contribution to journal › Review › Research › peer-review

  26. Published

    Astrocyte glycogen metabolism is required for neural activity during aglycemia or intense stimulation in mouse white matter

    Brown, A. M., Sickmann, H. M., Fosgerau, K., Lund, Trine Meldgaard, Schousboe, Arne, Waagepetersen, Helle S. & Ransom, B. R., 2005, In: Journal of Neuroscience Research. 79, 1-2, p. 74-80 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Astrocyte glycogenolysis is triggered by store-operated calcium entry and provides metabolic energy for cellular calcium homeostasis

    Müller, M. S., Fox, R., Schousboe, Arne, Waagepetersen, Helle S. & Bak, Lasse Kristoffer, Apr 2014, In: Glia. 62, 4, p. 526-34 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Astrocytes regulate inhibitory neurotransmission through GABA uptake, metabolism, and recycling

    Andersen, Jens Velde, Schousboe, Arne & Wellendorph, Petrine, 2023, In: Essays in Biochemistry. 67, 1, p. 77-91

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Astrocytic GABA Transporters: Pharmacological Properties and Targets for Antiepileptic Drugs

    Schousboe, Arne, Wellendorph, Petrine, Frølund, Bente, Clausen, Rasmus Prætorius & Krogsgaard-Larsen, Povl, 2017, Glial Amino Acid Transporters. Springer, Vol. 16. p. 283-296 14 p. (Advances in Neurobiology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  30. Published

    Astrocytic Metabolism Focusing on Glutamate Homeostasis: A Short Review Dedicated to Vittorio Gallo

    Schousboe, Arne, 2020, In: Neurochemical Research. 45, 3, p. 522-525

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Astrocytic control of biosynthesis and turnover of the neurotransmitters glutamate and GABA

    Schousboe, Arne, Bak, Lasse Kristoffer & Waagepetersen, Helle S., 15 Aug 2013, In: Frontiers in Endocrinology. 4, 102.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Astrocytic glycogen metabolism in the healthy and diseased brain

    Bak, Lasse Kristoffer, Walls, Anne Byriel, Schousboe, Arne & Waagepetersen, Helle S., 11 May 2018, In: The Journal of Biological Chemistry. 293, 19, p. 7108-7116 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  33. Published

    Astrocytic pyruvate carboxylation: Status after 35 years

    Schousboe, Arne, Waagepetersen, Helle S. & Sonnewald, U., 1 Jan 2019, In: Journal of Neuroscience Research. 97, p. 890-896

    Research output: Contribution to journal › Review › Research › peer-review

  34. Published

    Availability of neurotransmitter glutamate is diminished when beta-hydroxybutyrate replaces glucose in cultured neurons

    Lund, Trine Meldgaard, Risa, Ø., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 2009, In: Journal of Neurochemistry. 110, 1, p. 80-91 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Brain alanine formation as an ammonia-scavenging pathway during hyperammonemia: effects of glutamine synthetase inhibition in rats and astrocyte-neuron co-cultures

    Dadsetan, S., Kukolj, E., Bak, Lasse Kristoffer, Sørensen, M., Ott, P., Vilstrup, H., Schousboe, Arne, Keiding, S. & Waagepetersen, Helle S., Aug 2013, In: Journal of Cerebral Blood Flow and Metabolism. 33, 8, p. 1235-41 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Brain energy and ammonia metabolism

    Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2012, Functional molecular imaging in hepatology. Bentham Science Publishers, Vol. 1. p. 129-144 16 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  37. Published

    Brain energy and ammonia metabolism

    Bak, Lasse Kristoffer, Waagepetersen, Helle S. & Schousboe, Arne, 2011, Functional molecular imaging in hepatology. Bussum, The Netherlands: Bentham Science Publishers, p. 129-144

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  38. Published

    Brain glycogen: new perspectives on its metabolic function and regulation at the subcellular level

    Obel, L. L. F., Müller, M. S., Walls, Anne Byriel, Sickmann, H. M., Bak, Lasse Kristoffer, Waagepetersen, Helle S. & Schousboe, Arne, 2 Mar 2012, In: Frontiers in Neuroenergetics. 4, 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  39. Published

    Brain glycogen and its role in supporting glutamate and GABA homeostasis in a type 2 diabetes rat model

    Sickmann, H. M., Waagepetersen, Helle S., Schousboe, Arne, Benie, A. J. & Bouman, S. D., 2012, In: Neurochemistry International. 60, 3, p. 267-75 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Brain glycogen: emergency fuel and dynamic function in neurotransmission

    Walls, Anne Byriel & Schousboe, Arne, Feb 2015, In: Metabolic Brain Disease. 30, 1, p. 249-249 1 p.

    Research output: Contribution to journal › Journal article › Research

  41. Published

    Branched-chain amino acids increase arterial blood ammonia in spite of enhanced intrinsic muscle ammonia metabolism in patients with cirrhosis and healthy subjects

    Dam, G., Keiding, S., Munk, O. L., Ott, P., Buhl, M., Vilstrup, H., Bak, Lasse Kristoffer, Waagepetersen, Helle S., Schousboe, Arne, Møller, N. & Sørensen, M., 1 Aug 2011, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 301, 2, p. G269-77

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Cell proliferation, migration and CAM-dependent neurite outgrowth as developmental in vitro endpoints for screening teratogenic potential: Application to valproic acid and related analogues of .....

    Bacon, C. L., Berezin, V., Bode, G., Bock, E., Bojic, U., Doherty, P., Edvardsen, K., Ehlers, K., Ellerbeck, U., Julien, P., Kawa, A., Maar, T., Nau, H., Pirovano, R., Regan, C., Schousboe, Arne, Spezia, F., Walsh, F. S. & Williams, E. J., 1998, In: Toxicology in Vitro. 12, p. 101-109

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Characterization of 1,4-dideoxy-1,4-imino-d-arabinitol (DAB) as an inhibitor of brain glycogen shunt activity

    Walls, Anne Byriel, Sickmann, H. M., Brown, A., Bouman, S. D., Ransom, B., Schousboe, Arne & Waagepetersen, Helle S., 2008, In: Journal of Neurochemistry. 105, p. 1462-1470

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Characterization of NCAM diversity in cultured neurons

    Gegelashvili, G., Andersson, A., Schousboe, Arne & Bock, E., 1993, In: FEBS Letters. 324, p. 337-340

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Characterization of depolarization-coupled release of glutamate from cultured mouse cerebellar granule cells using DL-threo-beta-benzyloxyaspartate (DL-TBOA) to distinguish between the vesicular and cytoplasmic pools

    Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 14 May 2003, In: Neurochemistry International. 43, 4-5, p. 417-24 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Characterization of glutamate-induced formation of N- acylphosphatidylethanolamine and N-acylethanolamine in cultured neocortical neurons

    Hansen, Harald S., Lauritzen, Lotte, Strand, A. M., Vinggaard, A. M., Frandsen, Aase & Schousboe, Arne, 1 Aug 1997, In: Journal of Neurochemistry. 69, 2, p. 753-761 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Characterization of microwell cultures of dissociated brain tissue for studies of cell-cell interactions

    Maar, T. E., Rønn, L. C. B., Bock, E., Berezin, V., Moran, J., Pasantes-Moralez, H. & Schousboe, Arne, 1997, In: Journal of Neuroscience Research. 47, p. 163-172

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Characterization of primary and secondary cultures of astrocytes prepared from mouse cerebral cortex

    Jensen, Dorte Skytt, Madsen, K. K., Pajecka, K., Schousboe, Arne & Waagepetersen, Helle S., 2010, In: Neurochemical Research. 35, 12, p. 2043-2052 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Characterization of the 1H-cyclopentapyrimidine-2,4(1H,3H)-dione derivative (S)-CPW399 as a novel, potent, and subtype-selective AMPA receptor full agonist with partial desensitization properties

    Campiani, G., Morelli, E., Nacci, V., Fattorusso, C., Ramunno, A., Novellino, E., Greenwood, J., Liljefors, T., Griffiths, R., Sinclair, C., Reavy, H., Kristensen, A. S., Pickering, Darryl S, Schousboe, Arne, Cagnotto, A., Fumagalli, E., Mennini, T. & Pickering, Darryl S, 2001, In: Journal of Medicinal Chemistry. 44, 26, p. 4501-4 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Citrate, a Ubiquitous Key Metabolite with Regulatory Function in the CNS

    Westergaard, N., Waagepetersen, Helle S., Belhage, B. & Schousboe, Arne, Jun 2017, In: Neurochemical Research. 42, 6, p. 1583-1588 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Comparison of the agonist binding site of homomeric, heteromeric, and chimeric GluR1(o) and GluR3(o) AMPA receptors

    Banke, T. G., Schousboe, Arne, Pickering, D. S. & Pickering, D., 1997, In: Journal of Neuroscience Research. 49, 2, p. 176-85 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Complex actions of ionomycin in cultured cerebellar astrocytes affecting both calcium-induced calcium release and store-operated calcium entry

    Müller, M. S., Obel, L. L. F., Waagepetersen, Helle S., Schousboe, Arne & Bak, Lasse Kristoffer, Jun 2013, In: Neurochemical Research. 38, 6, p. 1260-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Complex glutamate labeling from [U-13C]glucose or [U-13C]lactate in co-cultures of cerebellar neurons and astrocytes

    Bak, Lasse Kristoffer, Waagepetersen, Helle S., Melø, T. M., Schousboe, Arne & Sonnewald, U., 2007, In: Neurochemical Research. 32, p. 671-680

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Correlation between Anticonvulsant Activity and Inhibitory Action on Glial -Aminobutyric Acid Uptake of the Highly Selective Mouse -Aminobutyric Acid Transporter 1 Inhibitor 3-Hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazole and Its N-Alkylated Analogs

    White, S., Sarup, A., Bolvig, T., Petersen, G., Nelson, N., Pickering, Darryl S, Larsson, O. M., Frølund, Bente, Falch, E., Krogsgaard-Larsen, Povl & Schousboe, Arne, 2002, In: Journal of Pharmacology and Experimental Therapeutics. 302, p. 636–644

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Cultured neurons as model systems for biochemical and pharmacological studies on receptors for neurotransmitter amino acids

    Schousboe, Arne, Drejer, J., Hansen, Gert Helge & Meier, E., 1985, In: Developmental Neuroscience. 7, 5-6, p. 252-62 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Cyclic AMP regulates NCAM expression and phosphorylation in cultures mouse astrocytes

    Gegelashvili, G., Andersson, A., Schousboe, Arne & Bock, E., 1993, In: European Journal of Cell Biology. 62, p. 343-351

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Deficient astrocyte metabolism impairs glutamine synthesis and neurotransmitter homeostasis in a mouse model of Alzheimer's disease

    Andersen, Jens Velde, Christensen, S. K., Westi, Emil Winther, Diaz-delcastillo, M., Tanila, H., Schousboe, Arne, Aldana, Blanca & Waagepetersen, Helle S., 2021, In: Neurobiology of Disease. 148, 13 p., 105198.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Accepted/In press

    Deletion of CaMKIIα disrupts glucose metabolism, glutamate uptake, and synaptic energetics in the cerebral cortex

    Andersen, Jens Velde, Westi, Emil Winther, Griem-Krey, Nane, Skotte, Niels Henning, Schousboe, Arne, Aldana, Blanca & Wellendorph, Petrine, 2023, (Accepted/In press) In: Journal of Neurochemistry.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Deletion of the betaine-GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult mice

    Lehre, A. C., Rowley, N. M., Zhou, Y., Holmseth, S., Guo, C., Holen, T., Hua, R., Laake, P., Olofsson, A. M., Poblete-Naredo, I., Rusakov, D. A., Madsen, K. K., Clausen, Rasmus Prætorius, Schousboe, Arne, White, H. S. & Danbolt, N. C., 1 Jun 2011, In: Epilepsy Research. 95, 1-2, p. 70-81

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Delineation of the Role of Astroglial GABA Transporters in Seizure Control

    Schousboe, Arne & Madsen, K. K., Jul 2017, In: Neurochemical Research. 42, 7, p. 2019-2023

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Demonstration of extensive GABA synthesis in the small population of GAD positive neurons in cerebellar cultures by the use of pharmacological tools

    Sonnewald, U., Kortner, T. M., Qu, H., Olstad, E., Suñol, C., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 7 Mar 2006, In: Neurochemistry International. 48, 6-7, p. 572-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Demonstration of neuron-glia transfer of precursors for Gaba biosynthesis in a co-culture system of dissociated mouse cerebral cortex

    Leke, R., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2008, In: Neurochemical Research. 33, 12, p. 2629-2635

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Depletion of polyamines prevents the neurotrophic activity of the GABA-agonist THIP in cultured rat cerebellar granule cells

    Abraham, J. H., Hansen, Gert Helge, Seiler, N. & Schousboe, Arne, 1993, In: Neurochemical Research. 18, 2, p. 153-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Depolarization by K+ and glutamate activates different neurotransmitter release mechanisms in GABAergic neurons: vesicular versus non-vesicular release of GABA

    Belhage, B., Hansen, Gert Helge & Schousboe, Arne, 1993, In: Neuroscience. 54, 4, p. 1019-34 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Depolarization-induced release of [(3)H]D-aspartate from GABAergic neurons caused by reversal of glutamate transporters

    Jensen, J. B., Pickering, Darryl S, Schousboe, Arne & Pickering, Darryl S, 2000, In: International Journal of Developmental Neuroscience. 18, 2-3, p. 309-15 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Design, synthesis, and characterisation of selective GABA transport inhibitors

    Clausen, Rasmus Prætorius, Moltzen, E., Perregaard, J., Lenz, S., Sanchez, S., Frølund, Bente, Bolvig, T., Sarup, A., Larsson, O., White, H., Schousboe, Arne & Krogsgaard-Larsen, Povl, Aug 2005, In: Journal of Neurochemistry. 94, p. 150-150

    Research output: Contribution to journal › Conference abstract in journal › Research

  67. Published

    Design, synthesis, and pharmacology of a highly subtype-selective GluR1/2 agonist, (RS)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid (Cl-HIBO)

    Bjerrum, E. J., Kristensen, Anders Skov, Pickering, D. S., Greenwood, J. R., Nielsen, Birgitte, Liljefors, T., Schousboe, Arne, Bräuner, Hans, Madsen, Ulf & Pickering, Darryl S, 2003, In: Journal of Medicinal Chemistry. 46, 11, p. 2246-9 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Determination of the phospholipid precursor of anandamide and other N- acylethanolamine phospholipids before and after sodium azide-induced toxicity in cultured neocortical neurons

    Hansen, H. H., Schousboe, Arne, Hansen, Harald S. & Hansen, S. H., 1 Jan 2000, In: Journal of Neurochemistry. 75, 2, p. 861-871 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Detoxification of ammonia in mouse cortical GABAergic cell cultures increases neuronal oxidative metabolism and reveals an emerging role for release of glucose-derived alanine

    Leke, R., Bak, Lasse Kristoffer, Anker, M., Melø, T. M., Sørensen, M., Keiding, S., Vilstrup, H., Ott, P., Portela, L. V., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 1 Apr 2011, In: Neurotoxicity Research. 19, 3, p. 496-510 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Development of calcium-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in cultured neocortical neurons visualized by cobalt staining

    Jensen, J. B., Schousboe, Arne, Pickering, Darryl S & Pickering, Darryl S, 1998, In: Journal of Neuroscience Research. 54, 2, p. 273-81 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Differential distribution of GABAA receptor subunits in soma and processes of cerebellar granule cells: effects of maturation and a GABA agonist

    Elster, L., Hansen, Gert Helge, Belhage, B., Fritschy, J. M., Möhler, H. & Schousboe, Arne, 1995, In: International Journal of Developmental Neuroscience. 13, 5, p. 417-28 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Differential effects of two GABA transport inhibitors, tiagabine and EF-1502, on phenytoin-resistant spontaneous bursting in the entorhinal cortex of slices from kainic acid treated rats

    Smith-Yockman, M., Saunders, G., Wilcox, K., Clausen, Rasmus Prætorius, Frølund, Bente, Larsson, O., Schousboe, Arne & White, H., 2005, In: Epilepsia. 46, p. 188-188

    Research output: Contribution to journal › Conference abstract in journal › Research

  73. Published

    Differential localization of voltage-gated calcium channels in neurites and somata of cultured neocortical neurons.

    Timmermann, D., Lund, Trine Meldgaard, Belhage, B. & Schousboe, Arne, 1999, In: Journal of Neurochemistry. 73, Suppl, p. 127 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  74. Published

    Direct measurement of backflux between oxaloacetate and fumarate following pyruvate carboxylation

    Brekke, E., Walls, Anne Byriel, Nørfeldt, L., Schousboe, Arne, Waagepetersen, Helle S. & Sonnewald, U., 2012, In: Glia. 60, 1, p. 147-58 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Discovery of a subtype-selective of the human betaine/GABA transporter 1 (BGT-1) with a non-competitive pharmacological profile

    Kragholm, B., Kvist, T., Madsen, K. K., Jørgensen, L., Vogensen, S. B., Schousboe, Arne, Clausen, Rasmus Prætorius, Jensen, Anders A. & Bräuner, Hans, 2013, In: Biochemical Pharmacology. 86, p. 521-528

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Downregulation of GABA Transporter 3 (GAT3) is Associated with Deficient Oxidative GABA Metabolism in Human Induced Pluripotent Stem Cell-Derived Astrocytes in Alzheimer's Disease

    Salcedo, C., Wagner, A., Andersen, Jens Velde, Vinten, K. T., Waagepetersen, Helle S., Schousboe, Arne, Freude, Kristine & Aldana, Blanca, 2021, In: Neurochemical Research. 46, p. 2676–2686

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Effect of a GABA agonist on the expression and distribution of GABAA receptors in the plasma membrane of cultured cerebellar granule cells: an immunocytochemical study

    Hansen, Gert Helge, Belhage, B. & Schousboe, Arne, 1991, In: Neuroscience Letters. 124, 2, p. 162-5 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Effect of glutamine synthetase inhibition on brain and interorgan ammonia metabolism in bile duct ligated rats

    Fries, A. W., Dadsetan, S., Keiding, S., Bak, Lasse Kristoffer, Schousboe, Arne, Waagepetersen, Helle S., Simonsen, M., Ott, P., Vilstrup, H. & Sørensen, M., Mar 2014, In: Journal of Cerebral Blood Flow and Metabolism. 34, 3, p. 460-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Effect of phenylsuccinate on potassium- and ischemia-induced release of glutamate in rat hippocampus monitored by microdialysis

    Christensen, T., Bruhn, T., Diemer, N. H. & Schousboe, Arne, 16 Dec 1991, In: Neuroscience Letters. 134, 1, p. 71-74 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Effect of tiagabine and EF1502 on phenytoin-resistant spontaneous bursts in the entorhinal cortex of slices from kainic acid-treated rats

    Smith-Yockman, M., Saunders, G., Wilcox, K., Larsson, O., Clausen, Rasmus Prætorius, Frølund, Bente, Schousboe, Arne & White, H., Aug 2005, In: Journal of Neurochemistry. 94, p. 256-256

    Research output: Contribution to journal › Conference abstract in journal › Research

  81. Published

    Effect of topiramate and dBcAMP on expression of the glutamate transporters GLAST and GLT-1 in astrocytes cultured separately, or together with neurons

    Poulsen, C. F., Schousboe, E. I., Sarup, A., White, H. S. & Schousboe, Arne, 2006, In: Neurochemistry International. 48, Sp. Iss. SI 6-7, p. 657-661 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Effects of 3-hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazol (exo-THPO) and its N-substituted analogs on GABA transport in cultured neurons and astrocytes and by the four cloned mouse GABA transporters

    sarup, A., Larsson, O. M., Bolvig, T., Frølund, Bente, Krogsgaard-Larsen, Povl & Schousboe, Arne, 2003, In: Neurochemistry International. 43, p. 445–451

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Effects of adrenergic agents on intracellular ca(2+) homeostasis and metabolism of glucose in astrocytes with an emphasis on pyruvate carboxylation, oxidative decarboxylation and recycling: implications for glutamate neurotransmission and excitotoxicity

    Obel, L. L. F., Andersen, K. M. H., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2012, In: Neurotoxicity Research. 21, 4, p. 405-17 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Effects of gamma-aminobutyric acid (GABA) on synaptogenesis and synaptic function

    Belhage, B., Hansen, Gert Helge, Elster, L. & Schousboe, Arne, 1998, In: Perspectives of Developmental Neurobiology. 5, 2-3, p. 235-46 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Effects of hyperammonemia on brain energy metabolism: controversial findings in vivo and in vitro

    Schousboe, Arne, Waagepetersen, Helle S., Leke, R. & Bak, Lasse Kristoffer, 1 Mar 2014, In: Metabolic Brain Disease. 29, 4, p. 913-917 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Effects of inhibitors of protein synthesis and intracellular transport on the gamma-aminobutyric acid agonist-induced functional differentiation of cultured cerebellar granule cells

    Belhage, B., Hansen, Gert Helge, Meier, E. & Schousboe, Arne, 1990, In: Journal of Neurochemistry. 55, 4, p. 1107-13 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Effects of taurine depletion on cell migration and NCAM expression in cultures of dissociated mouse cerebellum and N2A cells

    Maar, T. E., Lund, Trine Meldgaard, Gegelashvili, G., Hartmann-Petersen, Rasmus, Moran, M. J., Pasantes-Morales, H., Berezin, V., Bock, E. & Schousboe, Arne, 1998, In: Amino Acids. 15, 1, p. 77-88 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Energy Metabolism of the Brain

    McKenna, M. C., Dienel, G. A., Sonnewald, U., Waagepetersen, Helle S. & Schousboe, Arne, 1 Dec 2012, Basic Neurochemistry. Elsevier, p. 200-231 32 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  89. Published

    Energy substrates to support glutamatergic and GABAergic synaptic function: role of glycogen, glucose and lactate

    Schousboe, Arne, Bak, Lasse Kristoffer, Sickmann, H. M., Sonnewald, U. & Waagepetersen, Helle S., Dec 2007, In: Neurotoxicity Research. 12, 4, p. 263-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Energy substrates to support glutamatergic and GABAergic synaptic function: Role of glycogen, glucose and lactate

    Schousboe, Arne, Bak, Lasse Kristoffer, Sickmann, H. M., Sonnewald, U. & Waagepetersen, Helle S., 2007, In: Neurotoxicity Research. 12, 4, p. 263-268

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Erratum: Demonstration of neuron-glia transfer of precursors for gaba biosynthesis in a co-culture system of dissociated mouse cerebral cortex (Neurochem Res (2008) 33:26292635;DOI 10.1007/s11064-008-9814-6)

    Leke, R., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 1 Dec 2009, In: Neurochemical Research. 34, 12, 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  92. Published

    Evidence of Oatp and Mdr1 in cryopreserved rat hepatocytes

    Jørgensen, L., van Beek, J., Lund, S., Schousboe, Arne & Badolo, L., 2007, In: European Journal of Pharmaceutical Sciences. 30, 2, p. 181-189

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP

    Nielsen, B. B., Pickering, Darryl S, Greenwood, J. R., Brehm, L., Gajhede, Michael, Schousboe, Arne & Kastrup, Jette Sandholm Jensen, 2005, In: FEBS Journal. 272, 7, p. 1639-48 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Expression of glutamate decarboxylase (GAD) mRNA in the brain of bile duct ligated rats serving as a model of hepatic encephalopathy

    Leke, R., Silveira, T., Escobar, T. & Schousboe, Arne, 2014, In: Neurochemical Research. 39, 3, p. 605-611 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Expression of glutamine transporter isoforms in cerebral cortex of rats with chronic hepatic encephalopathy

    Leke, R., Escobar, T. D. C., Rama Rao, K. V., Silveira, T. R., Norenberg, M. D. & Schousboe, Arne, 2015, In: Neurochemistry International. 88, p. 32-37 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Expression of the GABA(A) receptor alpha6 subunit in cultured cerebellar granule cells is developmentally regulated by activation of GABA(A) receptors

    Carlson, B. X., Belhage, B., Hansen, Gert Helge, Elster, L., Olsen, R. W. & Schousboe, Arne, 1997, In: Journal of Neuroscience Research. 50, 6, p. 1053-62 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Expression of the human isoform of glutamate dehydrogenase, hGDH2, augments TCA cycle capacity and oxidative metabolism of glutamate during glucose deprivation in astrocytes

    Nissen, J. D., Lykke, K., Bryk, J., Stridh, M. H., Zaganas, I., Jensen, Dorte Skytt, Schousboe, Arne, Bak, Lasse Kristoffer, Enard, W., Pääbo, S. & Waagepetersen, Helle S., 2017, In: Glia. 65, 3, p. 474–488

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Extensive astrocyte metabolism of γ-aminobutyric acid (GABA) sustains glutamine synthesis in the mammalian cerebral cortex

    Andersen, Jens Velde, Jakobsen, Emil, Westi, Emil Winther, Lie, M. E. K., Voss, C. M., Aldana, Blanca, Schousboe, Arne, Wellendorph, Petrine, Bak, Lasse Kristoffer, Pinborg, Lars Hageman & Waagepetersen, Helle S., 2020, In: Glia. 68, 12, p. 2601-2612

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    First Demonstration of a Functional Role for CNS Betaine/GABA Transporter (mGAT2) Based on Synergistic Anticonvulsant Action Among Inhibitors of mGAT1 and mGAT2

    White, S., Watson, W. P., Hansen, S. L., Slough, S., Perregård, J., Sarup, A., Bolvig, T., Petersen, G., Larsson, O. M., Clausen, Rasmus Prætorius, Frølund, Bente, Falch, E., Krogsgaard-Larsen, Povl & Schousboe, Arne, 2005, In: The Journal of Pharmacology and Experimental Therapeutics. 312, p. 866–874

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    First direct electron microscopic visualization of a tight spatial coupling between GABAA-receptors and voltage-sensitive calcium channels

    Hansen, Gert Helge, Belhage, B. & Schousboe, Arne, 1992, In: Neuroscience Letters. 137, 1, p. 14-8 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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