Lars Hviid
Professor
Centre for Medical Parasitology
CMP
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-11-TR4
Member of:
SURFACE team
- 2024
- Published
Biomarker of Anopheles exposure in Ghanaian children with hemoglobin S and C
Londono-Renteria, B., Seidu, Zakaria, Lamptey, H., Ofori, M. F., Hviid, Lars & Lopez-Perez, Mary, 2024, In: Acta Tropica. 249, 8 p., 107043.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
PfEMP1 and var genes – Still of key importance in Plasmodium falciparum malaria pathogenesis and immunity
Hviid, Lars, Jensen, Anja Ramstedt & Deitsch, K. W., 2024, (E-pub ahead of print) Advances in Parasitology. Academic Press, 51 p. (Advances in Parasitology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Profiling the Plasmodium falciparum erythrocyte membrane protein 1-specific immununoglobulin G response among Ghanaian children with hemoglobin S and C
Oleinikov, A. V., Seidu, Zakaria, Oleinikov, I. V., Tetteh, M., Lamptey, H., Ofori, M. F., Hviid, Lars & Lopez-Perez, Mary, 2024, In: The Journal of Infectious Diseases. 229, 1, p. 203-213Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Plasmodium falciparum infection and naturally acquired immunity to malaria antigens among Ghanaian children in northern Ghana
Seidu, Zakaria, Lamptey, H., Lopez-Perez, Mary, Whittle, N. O., Oppong, S. K., Kyei-Baafour, E., Pobee, A. N. A., Adjei, G. O., Hviid, Lars & Ofori, M. F., 2023, In: Parasite Epidemiology and Control. 22, p. e00317Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A conformational epitope in placental malaria vaccine antigen VAR2CSA: What does it teach us?
Doritchamou, J. Y. A., Renn, J. P., Hviid, Lars & Duffy, P. E., 2023, In: PLoS Pathogens. 19, 5, e1011370.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-phosphatidylserine antibody levels are low in multigravid pregnant women in a malaria-endemic area in Nigeria, and do not correlate with anti-VAR2CSA antibodies
Fasanya, A., Mohammed, N., Saleh, B. H., Tijani, M. K., Teleka, A., Quintana Varon, Maria del Pilar, Hviid, Lars & Persson, K. E. M., 2023, In: Frontiers in Cellular and Infection Microbiology. 13, 1130186.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical and laboratory characteristics of children with sickle cell disease on hydroxyurea treated with artemether-lumefantrine for acute uncomplicated malaria
Segbefia, C., Amponsah, S. K., Afrane, A. K. A., Nyarko, M. Y., Brew, Y., Salifu, N., Ahorhorlu, S. Y., Sulley, A. M., Hviid, Lars, Ofori, M. F. & Adjei, G. O., 2023, In: Frontiers in Medicine. 10, p. 1291330Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High burden of asymptomatic malaria and anaemia despite high adherence to malaria control measures: a cross-sectional study among pregnant women across two seasons in a malaria-endemic setting in Ghana
Anabire, Nsoh Godwin, Aculley, B., Pobee, A., Kyei-Baafour, E., Awandare, G. A., Quintana Varon, Maria del Pilar, Hviid, Lars & Ofori, M. F., 2023, In: Infection. 51, 6, p. 1717-1729Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The rapid and spontaneous postpartum clearance of Plasmodium falciparum is related to expulsion of the placenta
Anabire, Nsoh Godwin, Quintana Varon, Maria del Pilar, Ofori, M. F. & Hviid, Lars, 2023, In: The Journal of Infectious Diseases. 228, 2, p. 196-201 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Analysis by flow cytometry of α2-macroglobulin and nonimmune IgM-binding to Plasmodium falciparum-infected erythrocytes
Hviid, Lars & Lopez-Perez, Mary, 2022, Malaria Immunology: Targeting the Surface of Infected Erythrocytes. Humana Press, Vol. 2470. p. 435-444 10 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Analysis of allelic cross-reactivity of monoclonal IgG antibodies by a multiplexed reverse FluoroSpot assay
Hoffmann-Veltung, H., Anabire, Nsoh Godwin, Ofori, M. F., Janhmatz, P., Ahlborg, N., Hviid, Lars & Quintana Varon, Maria del Pilar, 2022, In: eLife. 11, p. e79245Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA
Raghavan, Sai Sundar Rajan, Dagil, Robert, Lopez-Perez, Mary, Conrad, J., Bassi, Maria Rosaria, Quintana Varon, Maria del Pilar, Choudhary, Swati, Gustavsson, Tobias, Wang, Y., Gourdon, Pontus Emanuel, Ofori, M. F., Christensen, S. B., Minja, D. T. R., Schmiegelow, Christentze, Nielsen, Morten Agertoug, Barfod, Lea Klingenberg, Hviid, Lars, Salanti, Ali, Lavstsen, Thomas & Wang, Kaituo, 2022, In: PLoS Pathogens. 18, 11, e1010924.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enzyme-linked immunosorbent assay for activation of the classical complement pathway by Plasmodium falciparum-infected erythrocyte surface antigen-specific antibodies
Larsen, M. D., Bayarri-Olmos, R., Garred, Peter & Hviid, Lars, 2022, In: Methods in Molecular Biology. 2470, p. 673-678 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Frequency of electrocardiographic alterations and pericardial effusion in patients with uncomplicated malaria
Kaagaard, M. D., Matos, L. O., Holm, A. E., Gomes, L. C., Wegener, A., Lima, K. O., Vieira, I. V. M., de Souza, R. M., Marinho, C. R. F., Hviid, Lars, Vestergaard, L. S., Dominguez, Helena, Biering-Sørensen, Tor, Silvestre, O. M. & Brainin, P., 2022, In: American Journal of Cardiology. 165, p. 116-123Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ICAM-1-binding Plasmodium falciparum erythrocyte membrane protein 1 variants elicits opsonic-phagocytosis IgG responses in Beninese children
Suurbaar, Jennifer, Moussiliou, A., Tahar, R., Olsen, Rebecca Wendelboe, Adams, Yvonne, Dalgaard, Nanna, Baafour, E. K., Adukpo, S., Hviid, Lars, Kusi, K. A., Alao, J., Ofori, M. F., Ndam, N. T. & Jensen, Anja Ramstedt, 2022, In: Scientific Reports. 12, 12994.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of α2-macroglobulin, anti-parasite IgM and ABO blood group on rosetting in Plasmodium falciparum clinical isolates and their associations with disease severity in a Ghanaian population
Bandoh, B., Kyei-Baafour, E., Aculley, B., van der Puije, W., Tornyigah, B., Akyea-Mensah, K., Hviid, Lars, Ngala, R. A., Frempong, M. T. & Ofori, M. F., 2022, In: Journal of Blood Medicine. 13, p. 151-164 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Malaria immunology: Targeting the surface of infected erythrocytes
Jensen, Anja Ramstedt (ed.) & Hviid, Lars (ed.), 2022, Humana Press. 796 p. (Methods in Molecular Biology, Vol. 2470).Research output: Book/Report › Book › Research › peer-review
- Published
Natural acquired immunity to malaria antigens among pregnant women with hemoglobin C trait
Lopez-Perez, Mary, Viwami, F., Doritchamou, J., Ndam, N. T. & Hviid, Lars, 2022, In: American Journal of Tropical Medicine and Hygiene. 106, 3, p. 853–856Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No sweet deal: the antibody-mediated immune response to malaria
Hviid, Lars, Lopez-Perez, Mary, Larsen, M. D. & Vidarsson, G., 2022, In: Trends in Parasitology. 38, 6, p. 428-434Research output: Contribution to journal › Review › Research › peer-review
- Published
Prevalence and dynamic changes in lung ultrasound findings among adults with uncomplicated malaria and controls in the Amazon basin, Brazil
Wegener, A., Holm, A. E., Gomes, L. C., Lima, K. O., Matos, L. O., Vieira, I. V. M., Kaagaard, M. D., de Souza, R. M., Hviid, Lars, Guimarães Lacerda, M. V., Vestergaard, L. S., Farias Marinho, C. R., Platz, E., Biering-Sørensen, Tor, Silvestre, O. M. & Brainin, P., 2022, In: American Journal of Tropical Medicine and Hygiene. 106, 6, p. 1637-1645 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination
Larsen, M. D., Lopez-Perez, Mary, Dickson, E. K., Ampomah, P., Tuikue Ndam, N., Nouta, J., Koeleman, C. A. M., Ederveen, A. L. H., Mordmüller, B., Salanti, Ali, Nielsen, Morten Agertoug, Massougbodji, A., van der Schoot, C. E., Ofori, M. F., Wuhrer, M., Hviid, Lars & Vidarsson, G., 2021, In: Nature Communications. 12, 5838.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heart failure associated with imported malaria: A nationwide Danish cohort study
Brainin, P., Mohr, G. H., Modin, D., Claggett, B., Silvestre, O. M., Shah, A., Vestergaard, L. S., Jensen , Jens-Ulrik Stæhr , Hviid, Lars, Torp-Pedersen, Christian, Køber, Lars Valeur, Solomon, S., Schou, Morten, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2021, In: ESC heart failure. 8, 5, p. 3521-3529Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PfEMP1-specific immunoglobulin G reactivity among Beninese pregnant women with sickle cell trait
Lopez-Perez, Mary, Viwami, F., Seidu, Zakaria, Jensen, Anja Ramstedt, Doritchamou, J., Ndam, N. T. & Hviid, Lars, 2021, In: Open Forum Infectious Diseases. 8, 12, ofab527.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Suitability of IgG responses to multiple Plasmodium falciparum antigens as markers of transmission intensity and pattern
Kyei-Baafour, E., Oppong, M., Kusi, K. A., Frempong, A. F., Aculley, B., Arthur, F. K. N., Tiendrebeogo, R. W., Singh, S. K., Theisen, Michael, Kweku, M., Adu, B., Hviid, Lars & Ofori, M. F., 2021, In: PLoS ONE. 16, 4, e0249936.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Measuring naturally acquired phagocytosis-inducing antibodies to Plasmodium falciparum parasites by a flow cytometry-based assay
Quintana Varon, Maria del Pilar, Anabire, N. G. & Hviid, Lars, 6 Aug 2020, In: Journal of visualized experiments : JoVE. 162, e61538.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro selection for adhesion of Plasmodium falciparum-infected erythrocytes to ABO antigens does not affect PfEMP1 and RIFIN expression
van der Puije, W., Wang, Christian William, Sudharson, S., Hempel, C., Olsen, Rebecca Wendelboe, Dalgaard, Nanna, Ofori, M. F., Hviid, Lars, Kurtzhals, Jørgen & Staalsø, Trine, 2020, In: Scientific Reports. 10, 1, p. 12871 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acquisition and decay of IgM and IgG responses to merozoite antigens after Plasmodium falciparum malaria in Ghanaian children
Walker, Melanie Rose, Knudsen, Anne Schlitterlau, Partey, Frederica Dedo, Bassi, Maria Rosaria, Frank, A. M., Castberg, F. C., Sarbah, E. W., Ofori, M. F., Hviid, Lars & Barfod, Lea Klingenberg, 2020, In: PLoS ONE. 15, 12, p. e0243943Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Binding of human serum proteins to Plasmodium falciparum-infected erythrocytes and its association with malaria clinical presentation
Lopez-Perez, Mary, van der Puije, W., Castberg, F. C., Ofori, M. F. & Hviid, Lars, 2020, In: Malaria Journal. 19, 1, 362.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1-based vaccines to prevent it
Jensen, Anja Ramstedt, Adams, Yvonne & Hviid, Lars, 2020, In: Immunological Reviews. 293, 1, p. 230-252Research output: Contribution to journal › Review › Research › peer-review
- Published
Endemic Burkitt lymphoma - an aggressive childhood cancer linked to Plasmodium falciparum exposure, but not to exposure to other malaria parasites
Quintana Varon, Maria del Pilar, Smith-Togobo, C., Moormann, A. & Hviid, Lars, 2020, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 128, 2, p. 129-135Research output: Contribution to journal › Review › Research › peer-review
- Published
Precipitated malaria: It never rains but it pours
Hviid, Lars, 2020, In: Trends in Parasitology. 36, 9, p. 721-723 3 p.Research output: Contribution to journal › Letter › Research › peer-review
- 2019
- Published
Acquisition of IgG to ICAM-1-Binding DBLβ Domains in the Plasmodium falciparum erythrocyte membrane protein 1 antigen family varies between Groups A, B, and C
Olsen, Rebecca Wendelboe, Ecklu-Mensah, G., Bengtsson, A., Ofori, M. F., Kusi, K. A., Koram, K. A., Hviid, Lars, Adams, Yvonne & Jensen, Anja Ramstedt, 2019, In: Infection and Immunity. 87, 10, e00224-19.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comprehensive analysis of Fc-mediated IgM binding to the Plasmodium falciparum erythrocyte membrane protein 1 family in three parasite clones
Quintana Varon, Maria del Pilar, Ecklu-Mensah, G., Tcherniuk, S. O., Ditlev, S. B., Oleinikov, A. V., Hviid, Lars & Lopez-Perez, Mary, 2019, In: Scientific Reports. 9, 1, 11 p., 6050.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evasion of classical complement pathway activation on Plasmodium falciparum-infected erythrocytes opsonized by PfEMP1-specific IgG
Larsen, M. D., Quintana Varon, Maria del Pilar, Ditlev, S. B., Bayarri-Olmos, R., Ofori, M. F., Hviid, Lars & Garred, Peter, 2019, In: Frontiers in Immunology. 9, 3088.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional antibodies against placental malaria parasites are variant dependent and differ by geographic region
Doritchamou, J., Teo, A., Morrison, R., Arora, G., Kwan, J., Manzella-Lapeira, J., Medina-Maldonado, S., Langhorne, J., Hviid, Lars, Narum, D. L., Dicko, A., Fried, M. & Duffy, P. E., 2019, In: Infection and Immunity. 87, 7, 14 p., e00865-18.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High frequencies of tumor-infiltrating and circulating γδ T cells in endemic Burkitt lymphoma patients
Smith-Togobo, C., Quintana Varon, Maria del Pilar, Ofori, M. F. & Hviid, Lars, 2019, In: American Journal of Tropical Medicine and Hygiene. 101, S5, p. 563-563 1830.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Human Vδ1+ T cells in the immune response to Plasmodium falciparum infection
Hviid, Lars, Smith-Togobo, C. & Willcox, B. E., 2019, In: Frontiers in Immunology. 10, 5 p., 259.Research output: Contribution to journal › Review › Research › peer-review
- Published
Looking for needles in the Plasmodial haystack
Hviid, Lars, 2019, In: mSphere. 4, 2, 3 p., e00146-19.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reliable cell and tissue morphology-based diagnosis of endemic Burkitt lymphoma in resource-constrained settings in Ghana
Smith-Togobo, C., Pedersen, Mette Ølgod, Jensen, S. G., Duduyemi, B., Gyasi, R. K., Ofori, M. F., Paintsil, V., Renner, L., Nørgaard, P. & Hviid, Lars, 2019, In: BMC Cancer. 19, 7 p., 1270.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Malaria causes long-term effects on markers of iron status in children: a critical assessment of existing clinical and epidemiological tools
Castberg, F. C., Sarbah, E. W., Koram, K. A., Opoku, N., Ofori, M. F., Styrishave, Bjarne, Hviid, Lars & Kurtzhals, Jørgen, 11 Dec 2018, In: Malaria Journal. 17, 1, 464.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A vaccine targeted specifically to prevent cerebral malaria - is there hope?
Hviid, Lars, Lavstsen, Thomas & Jensen, Anja Ramstedt, Jul 2018, In: Expert Review of Vaccines. 17, 7, p. 565-567 3 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Increased Plasmodium chabaudi malaria mortality in mice with nutritional iron deficiency can be reduced by short-term adjunctive iron supplementation
Castberg, F. C., Maretty, L., Staalsø, Trine, Hempel, C., Clasen-Linde, E., Hviid, Lars & Kurtzhals, Jørgen, 16 Jan 2018, In: Malaria Journal. 17, 1, 12 p., 34.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Blood outgrowth endothelial cells (BOECs) as a novel tool for studying adhesion of Plasmodium falciparum-infected erythrocytes
Ecklu-Mensah, G., Olsen, Rebecca Wendelboe, Bengtsson, A., Ofori, M. F., Hviid, Lars, Jensen, Anja Ramstedt & Adams, Yvonne, 2018, In: PLoS ONE. 13, 10, 12 p., e0204177.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Etiology of placental Plasmodium falciparum malaria in African women
Ofori, M. F., Lamptey, H., Dickson, E. K., Kyei-Baafour, E. & Hviid, Lars, 2018, In: The Journal of Infectious Diseases. 218, 2, p. 277-281 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IgG responses to the Plasmodium falciparum antigen VAR2CSA in Colombia are restricted to pregnancy and are not induced by exposure to Plasmodium vivax
Lopez-Perez, Mary, Larsen, M. D., Bayarri-Olmos, R., Ampomah, P., Stevenson, L., Arévalo-Herrera, M., Herrera, S. & Hviid, Lars, 2018, In: Infection and Immunity. 86, 8, e00136-18.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetics of antibody responses to PfRH5-complex antigens in Ghanaian children with Plasmodium falciparum malaria
Partey, Frederica Dedo, Castberg, F. C., Sarbah, E. W., Silk, S. E., Awandare, G. A., Draper, S. J., Opoku, N., Kweku, M., Ofori, M. F., Hviid, Lars & Barfod, Lea Klingenberg, 2018, In: PLOS ONE. 13, 6, 14 p., e0198371.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Natural and vaccine-induced acquisition of cross-reactive IgG inhibiting ICAM-1-specific binding of a Plasmodium falciparum PfEMP1 subtype associated specifically with cerebral malaria
Olsen, Rebecca Wendelboe, Ecklu-Mensah, G., Bengtsson, A., Ofori, M. F., Lusingu, J. P. A., Castberg, F. C., Hviid, Lars, Adams, Yvonne & Jensen, Anja Ramstedt, 2018, In: Infection and Immunity. 86, 4, 17 p., e00622-17.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Structure-guided identification of a family of dual receptor-binding PfEMP1 that is associated with cerebral malaria
Lennartz, F., Adams, Y., Bengtsson, A., Olsen, R. W., Turner, L., Ndam, N. T., Ecklu-Mensah, G. D., Moussiliou, A., Ofori, M. F., Gamain, B., Lusingu, J. P., Petersen, J. E. V., Wang, C. W., Nunes-Silva, S., Jespersen, J. S., Lau, C. K. Y., Theander, T. G., Lavstsen, T., Hviid, L., Higgins, M. K. & 1 others, , 8 Mar 2017, In: Cell Host & Microbe. 21, 3, p. 403-414 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dansk malariaforskning fra spæd begyndelse til international styrkeposition
Jepsen, M. P. G., Jepsen, S., Kurtzhals, Jørgen & Hviid, Lars, 2017, In: Ugeskrift for Laeger. 179, 20, p. 866-869 V10160756.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Malaria parasite evasion of classical complement pathway attack
Larsen, M. D., Ditlev, S., Olmos, R. B., Ampomah, P., Ofori, M. F., Garred, Peter & Hviid, Lars, 2017, In: Molecular Immunology. 89, p. 159-159Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- 2016
- Published
Orm i toilettet
Hviid, Lars, Møller-Bisgaard, S. & Kurtzhals, Jørgen, 15 Feb 2016, In: Ugeskrift for Laeger. 178, 7, 1 p., V67428.Research output: Contribution to journal › Journal article › Communication
- Published
Immunoglobulin M: restrainer of inflammation and mediator of immune evasion by Plasmodium falciparum malaria
Pleass, R. J., Moore, S. C., Stevenson, L. & Hviid, Lars, Feb 2016, In: Trends in Parasitology. 32, 2, p. 108-119 12 p.Research output: Contribution to journal › Review › Research › peer-review
- 2015
- Published
Rifins, rosetting, and red blood cells
Wang, Christian William & Hviid, Lars, Jul 2015, In: Trends in Parasitology. 31, 7, p. 285-6 2 p.Research output: Contribution to journal › Journal article › Commissioned › peer-review
- Published
α2-macroglobulin can crosslink multiple Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) molecules and may facilitate adhesion of parasitized erythrocytes
Stevenson, L., Laursen, E., Cowan, G. J., Bandoh, B., Barfod, Lea Klingenberg, Cavanagh, D. R., Andersen, G. R. & Hviid, Lars, Jul 2015, In: P L o S Pathogens. 11, 7, p. 1-19 19 p., e1005022.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigating the function of Fc -specific binding of IgM to Plasmodium falciparum erythrocyte membrane protein 1 mediating erythrocyte rosetting
Stevenson, L., Huda, P., Jeppesen, A., Laursen, E. T. F., Rowe, J. A., Craig, A., Streicher, W., Barfod, Lea Klingenberg & Hviid, Lars, Jun 2015, In: Cellular Microbiology. 17, 6, p. 819-31 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PfEMP1 – a parasite protein family of key importance in Plasmodium falciparum malaria immunity and pathogenesis
Hviid, Lars & Jensen, Anja Ramstedt, Apr 2015, Advances in Parasitology. Rollinson, D. & Stothard, J. R. (eds.). Vol. 88. p. 51-84 34 p. (Advances in Parasitology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Trying to remember: immunological B cell memory to malaria
Hviid, Lars, Barfod, Lea Klingenberg & Fowkes, F. J. I., Mar 2015, In: Trends in Parasitology. 31, 3, p. 89-94 6 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Plasmodium falciparum-infected erythrocyte knob density is linked to the PfEMP1 variant expressed
Subramani, R., Quadt, K., Jeppesen, A. E., Hempel, C., Petersen, J. E. V., Hassenkam, Tue, Hviid, Lars & Barfod, Lea Klingenberg, 2015, In: mBio. 6, 5, 7 p., e01456-15.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multiple Plasmodium falciparum erythrocyte membrane protein 1 variants per genome can bind IgM via its Fc fragment Fcμ
Jeppesen, A., Ditlev, S. B., Soroka, V., Stevenson, E. K., Turner, Louise, Dzikowski, R., Hviid, Lars & Barfod, Lea Klingenberg, 2015, In: Infection and Immunity. 83, 10, p. 3972-81 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Kinetics of B Cell responses to Plasmodium falciparum erythrocyte membrane protein 1 in Ghanaian women naturally exposed to malaria parasites
Ampomah, P., Stevenson, L., Ofori, M. F., Barfod, Lea Klingenberg & Hviid, Lars, 1 Jun 2014, In: Journal of Immunology. 192, 11, p. 5236-44 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
B-cell responses to pregnancy-restricted and -unrestricted Plasmodium falciparum erythrocyte membrane protein 1 antigens in Ghanaian women naturally exposed to malaria parasites
Ampomah, P., Stevenson, L., Ofori, M. F., Barfod, Lea Klingenberg & Hviid, Lars, May 2014, In: Infection and Immunity. 82, 5, p. 1860-71 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites
Sleebs, B. E., Lopaticki, S., Marapana, D. S., O'Neill, M. T., Rajasekaran, P., Gazdik, M., Günther, S., Whitehead, L. W., Lowes, K. N., Barfod, Lea Klingenberg, Hviid, Lars, Shaw, P. J., Hodder, A. N., Smith, B. J., Cowman, A. F. & Boddey, J. A., 2014, In: P L o S Biology. 12, 7, p. e1001897Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modeling malaria infection and immunity against variant surface antigens in Príncipe island, West Africa
Bandeiras, C., Trovoada, M. J., Gonçalves, L. A., Marinho, C. R. F., Turner, Louise, Hviid, Lars, Penha-Gonçalves, C. & Gomes, M. G. M., 2014, In: PloS one. 9, 2, p. e88110Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Cytokine response to pregnancy-associated recrudescence of Plasmodium berghei infection in mice with pre-existing immunity to malaria
Megnekou, R., Staalsø, Trine & Hviid, Lars, 1 Nov 2013, In: Malaria Journal. 12, 1, p. 387Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Malaria
Riley, E. M., Hviid, Lars & Theander, Thor Grundtvig, 22 Oct 2013, Parasitic Infections and the Immune System. Elsevier Science Inc., p. 119-143 25 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
A Novel Domain Cassette Identifies Plasmodium falciparum PfEMP1 Proteins Binding ICAM-1 and Is a Target of Cross-Reactive, Adhesion-Inhibitory Antibodies
Bengtsson, A., Joergensen, L., Rask, T. S., Olsen, R. W., Andersen, M. A., Turner, Louise, Theander, Thor Grundtvig, Hviid, Lars, Higgins, M. K., Craig, A., Brown, A. & Jensen, Anja Ramstedt, 2013, In: Journal of Immunology. 190, 1, p. 240-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasmodium falciparum Expressing Domain Cassette 5 Type PfEMP1 (DC5-PfEMP1) Bind PECAM1
Berger, S. S., Turner, Louise, Wang, Christian William, Petersen, J. E. V., Kraft, M., Lusingu, J. P. A., Mmbando, B., Marquard, A. M., Bengtsson, D. B. A. C., Hviid, Lars, Nielsen, Morten Agertoug, Theander, Thor Grundtvig & Lavstsen, Thomas, 2013, In: PloS one. 8, 7, p. e69117Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transfected HEK293 Cells Expressing Functional Recombinant Intercellular Adhesion Molecule 1 (ICAM-1) - A Receptor Associated with Severe Plasmodium falciparum Malaria
Bengtsson, A., Joergensen, L., Barbati, Z. R., Craig, A., Hviid, Lars & Jensen, Anja Ramstedt, 2013, In: PLOS ONE. 8, 7, p. e69999Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Aligned hemozoin crystals in curved clusters in malarial red blood cells revealed by nanoprobe X-ray Fe fluorescence and diffraction
Kapishnikov, S., Berthing, T., Hviid, Lars, Dierolf, M., Menzel, A., Pfeiffer, F., Als-Nielsen, Jens & Leiserowitz, L., 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 28, p. 11184-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insights into deregulated TNF and IL-10 production in malaria: implications for understanding severe malarial anaemia
Boeuf, P. S., Loizon, S., Awandare, G. A., Tetteh, J. K., Addae, M. M., Adjei, G. O., Goka, B., Kurtzhals, Jørgen, Puijalon, O., Hviid, Lars, Akanmori, B. D. & Behr, C., 2012, In: Malaria Journal. 11, 1, p. 253Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The density of knobs on Plasmodium falciparum-infected erythrocytes depends on developmental age and varies among isolates
Quadt, K. A., Barfod, Lea Klingenberg, Andersen, D., Bruun, J., Gyan, B., Hassenkam, Tue, Ofori, M. F. & Hviid, Lars, 2012, In: P L o S One. 7, 9, p. e45658Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Evasion of immunity to Plasmodium falciparum malaria by IgM masking of protective IgG epitopes in infected erythrocyte surface-exposed PfEMP1
Barfod, Lea Klingenberg, Dalgaard, M. B., Pleman, S. T., Ofori, M. F., Pleass, R. J. & Hviid, Lars, 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 30, p. 12485-90 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The case for PfEMP1-based vaccines to protect pregnant women against Plasmodium falciparum malaria
Hviid, Lars, 2011, In: Expert Review of Vaccines. 10, 10, p. 1405-14 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Chondroitin sulfate A-adhering Plasmodium falciparum-infected erythrocytes express functionally important antibody epitopes shared by multiple variants
Barfod, Lea Klingenberg, Dobrilovic, T., Magistrado, P., Khunrae, P., Viwami, F., Bruun, J., Dahlbäck, M., Bernasconi, N. L., Fried, M., John, D., Duffy, P. E., Salanti, Ali, Lanzavecchia, A., Lim, C. T., Ndam, N. T., Higgins, M. K. & Hviid, Lars, 2010, In: Journal of Immunology. 185, 12, p. 7553-61 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian children
Cham, G. K. K., Turner, Louise, Kurtis, J. D., Mutabingwa, T., Fried, M., Jensen, Anja Ramstedt, Lavstsen, Thomas, Hviid, Lars, Duffy, P. E. & Theander, Thor Grundtvig, 2010, In: Infection and Immunity. 78, 11, p. 4653-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immune selection and within-host competition can structure the repertoire of variant surface antigens in Plasmodium falciparum -a mathematical model
van Noort, S. P., Nunes, M. C., Weedall, G. D., Hviid, Lars & Gomes, M. G. M., 2010, In: PLoS ONE. 5, 3, p. e9778Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Of mice and women: rodent models of placental malaria
Hviid, Lars, Marinho, C. R. F., Staalsø, Trine & Penha-Gonçalves, C., 2010, In: Trends in Parasitology. 26, 8, p. 412-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The kinetics of antibody binding to Plasmodium falciparum VAR2CSA PfEMP1 antigen and modelling of PfEMP1 antigen packing on the membrane knobs
Joergensen, L. M., Salanti, Ali, Dobrilovic, T., Barfod, Lea Klingenberg, Hassenkam, Tue, Theander, Thor Grundtvig, Hviid, Lars & Arnot, D. E., 2010, In: Malaria Journal. 9, 1, p. 100Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of Plasmodium falciparum variant surface antigens in protective immunity and vaccine development
Hviid, Lars, 2010, In: Human Vaccines. 6, 1, p. 84-89 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Human monoclonal IgG selection of Plasmodium falciparum for the expression of placental malaria-specific variant surface antigens
Soerli, J., Barfod, Lea Klingenberg, Lavstsen, Thomas, Bernasconi, N. L., Lanzavecchia, A. & Hviid, Lars, 2009, In: Parasite Immunology. 31, 6, p. 341-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pregnancy-associated malaria in a rural community of Ghana
Ofori, M., Ansah, E., Agyepong, I., Ofori-Adjei, D., Hviid, Lars & Akanmori, B., 2009, In: Ghana Medical Journal. 43, 1, p. 13-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unraveling the impact of malaria exposure before birth
Hviid, Lars, 2009, In: PLoS Medicine. 6, 7, p. e1000117Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variant-specific immunity to Plasmodium berghei in pregnant mice
Megnekou, R., Hviid, Lars & Staalsoe, T., 2009, In: Infection and Immunity. 77, 5, p. 1827-34 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
CD36 selection of 3D7 Plasmodium falciparum associated with severe childhood malaria results in reduced VAR4 expression
Magistrado, P., Staalsoe, T., Theander, Thor Grundtvig, Hviid, Lars & Jensen, Anja Ramstedt, 2008, In: Malaria Journal. 7, 1, p. 204Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differences in human antibody reactivity to Plasmodium falciparum variant surface antigens are dependent on age and malaria transmission intensity in northeastern Tanzania
Vestergaard, L. S., Lusingu, J. P., Nielsen, Morten Agertoug, Mmbando, B. P., Dodoo, D., Akanmori, B. D., Alifrangis, Michael, Bygbjerg, Ib Christian, Lemnge, M. M., Staalsoe, T., Hviid, Lars & Theander, Thor Grundtvig, 2008, In: Infection and Immunity. 76, 6, p. 2706-14 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Malaria vaccines: immunity, models and monoclonal antibodies
Hviid, Lars & Barfod, Lea Klingenberg, 2008, In: Trends in Parasitology. 24, 9, p. 392-395 3 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
VAR2CSA expression on the surface of placenta-derived Plasmodium falciparum-infected erythrocytes
Magistrado, P., Salanti, Ali, Tuikue Ndam, N. G., Mwakalinga, S. B., Resende, M., Dahlbäck, M., Hviid, Lars, Lusingu, J., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2008, In: Journal of Infectious Diseases.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Plasmodium falciparum: VAR2CSA expressed during pregnancy-associated malaria is partially resistant to proteolytic cleavage by trypsin
Nielsen, Morten Agertoug, Resende, M., Alifrangis, Michael, Turner, Louise, Hviid, Lars, Theander, Thor Grundtvig & Salanti, Ali, 2007, In: Experimental Parasitology. 117, 1, p. 1-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adhesion specificities of Plasmodium falciparum-infected erythrocytes involved in the pathogenesis of pregnancy-associated malaria
Hviid, Lars, 2007, In: American Journal of Pathology. 170, 6, p. 1817-9 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Changes in var gene mRNA levels during erythrocytic development in two phenotypically distinct Plasmodium falciparum parasites
Dahlbäck, M., Lavstsen, Thomas, Salanti, Ali, Hviid, Lars, Arnot, D. E., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2007, In: Malaria Journal. 6, p. 78Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Developing Plasmodium falciparum malaria vaccines for populations living in areas with stable parasite transmission
Hviid, Lars & Theander, Thor Grundtvig, 2007, In: International Journal of Biotechnology. 9, 3/4, p. 292-300 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of vaccines against Plasmodium falciparum malaria: taking lessons from naturally acquired protective immunity
Hviid, Lars, 2007, In: Microbes and Infection. 9, 6, p. 772-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA
Barfod, Lea Klingenberg, Bernasconi, N. L., Dahlbäck, M., Jarrossay, D., Andersen, P. H., Salanti, Ali, Ofori, M. F., Turner, Louise, Resende, M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sallusto, F., Lanzavecchia, A. & Hviid, Lars, 2007, In: Molecular Microbiology. 63, 2, p. 335-47 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunoglobulin G antibody reactivity to a group A Plasmodium falciparum erythrocyte membrane protein 1 and protection from P. falciparum malaria
Magistrado, P. A., Lusingu, J., Vestergaard, L. S., Lemnge, M., Lavstsen, Thomas, Turner, Louise, Hviid, Lars, Jensen, Anja Ramstedt & Theander, Thor Grundtvig, 2007, In: Infection and Immunity. 75, 5, p. 2415-20 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Malaria in pregnancy: pathogenesis and immunity
Rogerson, S. J., Hviid, Lars, Duffy, P. E., Leke, R. F. G. & Taylor, D. W., 2007, In: Lancet Infectious Diseases. 7, 2, p. 105-17 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selective activation of TCR-G¿ cells in endemic Burkitt's lymphoma
Futagbi, G., Welbeck, J. E., Tetteh, J. K. A., Hviid, Lars & Akanmori, B. D., 2007, In: Malaria Journal. 6, p. 69Research output: Contribution to journal › Journal article › Research › peer-review
- Published
VAR2CSA and protective immunity against pregnancy-associated Plasmodium falciparum malaria
Hviid, Lars & Salanti, Ali, 2007, In: Parasitology. 134, Pt 13, p. 1871-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vß profiles in African children with acute cerebral or uncomplicated malaria: very focused changes among a remarkable global stability
Loizon, S., Boeuf, P., Tetteh, J. K. A., Goka, B., Obeng-Adjei, G., Kurtzhals, J. A. L., Rogier, C., Akanmori, B. D., Mercereau-Puijalon, O., Hviid, Lars & Behr, C., 2007, In: Microbes and Infection. 9, 11, p. 1252-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Baculovirus-expressed constructs induce immunoglobulin G that recognizes VAR2CSA on Plasmodium falciparum-infected erythrocytes
Barfod, Lea Klingenberg, Nielsen, Morten Agertoug, Turner, Louise, Dahlbäck, M., Jensen, Anja Ramstedt, Hviid, Lars, Theander, Thor Grundtvig & Salanti, Ali, 2006, In: Infection and Immunity. 74, 7, p. 4357-60 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasmodium falciparum parasites expressing pregnancy-specific variant surface antigens adhere strongly to the choriocarcinoma cell line BeWo
Haase, R. N., Megnekou, R., Lundquist, M., Ofori, M. F., Hviid, Lars & Staalsoe, T., 2006, In: Infection and Immunity. 74, 5, p. 3035-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 3620
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Kinetics of B Cell responses to Plasmodium falciparum erythrocyte membrane protein 1 in Ghanaian women naturally exposed to malaria parasites
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Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites
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B-cell responses to pregnancy-restricted and -unrestricted Plasmodium falciparum erythrocyte membrane protein 1 antigens in Ghanaian women naturally exposed to malaria parasites
Research output: Contribution to journal › Journal article › Research › peer-review
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