Emil Jakobsen
PhD Student
Molecular and Cellular Pharmacology
Jagtvej 160, København Ø
- Published
The inhibitors of soluble adenylate cyclase 2-OHE, KH7, and bithionol compromise mitochondrial ATP production by distinct mechanisms
Jakobsen, Emil, Lange, S. C., Andersen, Jens Velde, Desler, Claus, Kihl, H. F., Hohnholt, M., Stridh, M. H., Rasmussen, Lene Juel, Waagepetersen, Helle S. & Bak, Lasse Kristoffer, 2018, In: Biochemical Pharmacology. 155, p. 92-101 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The energetic brain - A review from students to students
Bordone, M. P., Salman, M. M., Titus, H. E., Amini, E., Andersen, J. V., Chakraborti, B., Diuba, A. V., Dubouskaya, T. G., Ehrke, E., Freitas, A. E., Freitas, G. B., Gonçalves, R. A., Gupta, D., Ha, S. R., Hemming, I. A., Jaggar, M., Jakobsen, E., Kumari, P., Lakkappa, N., L Marsh, A. P. & 14 others, , Oct 2019, In: Journal of Neurochemistry. 151, 2, p. 139-165Research output: Contribution to journal › Review › Research › peer-review
- Published
Soluble adenylyl cyclase-mediated cAMP signaling and the putative role of PKA and EPAC in cerebral mitochondrial function
Jakobsen, Emil, Lange, S. C. & Bak, Lasse Kristoffer, Aug 2019, In: Journal of Neuroscience Research. 97, 8, p. 1018-1038 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of translation by site-specific ribosomal RNA methylation
Jansson, Martin David, Häfner, Sophia Julia, Altinel, Kübra, Tehler, D. E., Krogh, Nicolai, Jakobsen, Emil, Andersen, Jens Velde, Andersen, Kasper Langebjerg, Schoof, E., Ménard, Patrice, Nielsen, Henrik & Lund, Anders H., 2021, In: Nature Structural and Molecular Biology. 28, 11, p. 889-899Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacological inhibition of mitochondrial soluble adenylyl cyclase in astrocytes causes activation of AMP-activated protein kinase and induces breakdown of glycogen
Jakobsen, Emil, Andersen, Jens Velde, Christensen, S. K., Siamka, O., Larsen, M. R., Waagepetersen, Helle S., Aldana, Blanca & Bak, Lasse Kristoffer, 2021, In: Glia. 69, 12, p. 2828-2844 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of soluble adenylyl cyclase (SAC) causes a robust increase in glycolysis in cultured astrocytes
Jakobsen, Emil, Madsen, S. F., Hedehus, J., Rubio-Villena, C., Jorgensen, N. H. & Bak, Lasse Kristoffer, Aug 2017, p. 147-147.Research output: Contribution to conference › Poster › Research
- Published
Glycogen Shunt Activity and Glycolytic Supercompensation in Astrocytes May Be Distinctly Mediated via the Muscle Form of Glycogen Phosphorylase
Jakobsen, Emil, Bak, Lasse Kristoffer, Walls, Anne Byriel, Christiansen, Ann-Kathrin Lindahl, Schousboe, Arne & Waagepetersen, Helle S., Sep 2017, In: Neurochemical Research. 42, 9, p. 2490-2494 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glutamate metabolism and recycling at the excitatory synapse in health and neurodegeneration
Andersen, Jens Velde, Markussen, K. H., Jakobsen, Emil, Schousboe, Arne, Waagepetersen, Helle S., Rosenberg, P. A. & Aldana, Blanca, 2021, In: Neuropharmacology. 196, 14 p., 108719.Research output: Contribution to journal › Review › Research › peer-review
- Published
Extensive astrocyte metabolism of γ-aminobutyric acid (GABA) sustains glutamine synthesis in the mammalian cerebral cortex
Andersen, Jens Velde, Jakobsen, Emil, Westi, Emil Winther, Lie, M. E. K., Voss, C. M., Aldana, Blanca, Schousboe, Arne, Wellendorph, Petrine, Bak, Lasse Kristoffer, Pinborg, Lars Hageman & Waagepetersen, Helle S., 2020, In: Glia. 68, 12, p. 2601-2612Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Excitotoxic superoxide production and neuronal death require both ionotropic and non-ionotropic NMDA receptor signaling
Minnella, A. M., Zhao, J. X., Jiang, X., Jakobsen, Emil, Lu, F., Wu, L., El-Benna, J., Gray, J. A. & Swanson, R. A., 30 Nov 2018, In: Scientific Reports. 8, 1, 13 p., 17522.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Divergent Cellular Energetics, Glutamate Metabolism, and Mitochondrial Function Between Human and Mouse Cerebral Cortex
Westi, Emil Winther, Jakobsen, Emil, Voss, C. M., Bak, Lasse Kristoffer, Pinborg, Lars Hageman, Aldana, Blanca & Andersen, J. V., 2022, In: Molecular Neurobiology. 59, p. 7495–7512Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distinct effects on cAMP signaling of carbamazepine and its structural derivatives do not correlate with their clinical efficacy in epilepsy
Krarup, S., Mertz, C., Jakobsen, Emil, Lindholm, S. E. H., Pinborg, Lars Hageman & Bak, Lasse Kristoffer, 2020, In: European Journal of Pharmacology. 886, 11 p., 173413.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distinct differences in rates of oxygen consumption and ATP synthesis of regionally isolated non-synaptic mouse brain mitochondria
Andersen, Jens Velde, Jakobsen, Emil, Waagepetersen, Helle S. & Aldana, Blanca, 2019, In: Journal of Neuroscience Research. 97, p. 961–974Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential Expression of the β3 Subunit of Voltage-Gated Ca2+ Channel in Mesial Temporal Lobe Epilepsy
Kjær, C., Palasca, Oana, Barzaghi, G., Bak, Lasse Kristoffer, Durhuus, R. K. J., Jakobsen, Emil, Pedersen, Louise, Bartels, Emil Daniel, Woldbye, David Paul Drucker, Pinborg, Lars Hageman & Jensen, Lars Juhl, 2023, In: Molecular Neurobiology. 60, p. 5755–5769Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Compartmentalised signalling-metabolism coupling in brain cells - putative drug targets for neurological diseases?
Bak, Lasse Kristoffer, Christiansen, Ann-Kathrin Lindahl, Kjaer, C., Jakobsen, Emil, Hedehus, J., Mertz, C., Madsen, S., Jensen, M., Bergstedt, N., Knezevic, A. & Lindholm, S., Aug 2017, In: Journal of Neurochemistry. 142, S1, p. 145-145Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Astrocyte metabolism of the medium-chain fatty acids octanoic acid and decanoic acid promotes GABA synthesis in neurons via elevated glutamine supply
Andersen, Jens Velde, Westi, Emil Winther, Jakobsen, Emil, Urruticoechea, N., Borges, K. & Aldana, Blanca, 2021, In: Molecular Brain. 14, 1, 13 p., 132.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aspects of astrocytic cAMP signaling with an emphasis on the putative power of compartmentalized signals in health and disease
Christiansen, Ann-Kathrin Lindahl, Jakobsen, Emil, Mertz, C. & Bak, Lasse Kristoffer, 2019, In: Glia. 67, 9, p. 1625-1636Research output: Contribution to journal › Review › Research › peer-review
- Published
AMP-activated protein kinase (AMPK) regulates astrocyte oxidative metabolism by balancing TCA cycle dynamics
Voss, C. M., Andersen, Jens Velde, Jakobsen, Emil, Siamka, O., Karaca, M., Maechler, P. & Waagepetersen, Helle S., 2020, In: Glia. 68, 9, p. 1824-1839 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 165301014
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Distinct differences in rates of oxygen consumption and ATP synthesis of regionally isolated non-synaptic mouse brain mitochondria
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
321
downloads
Compartmentalised signalling-metabolism coupling in brain cells - putative drug targets for neurological diseases?
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published -
195
downloads
Inhibition of soluble adenylyl cyclase (SAC) causes a robust increase in glycolysis in cultured astrocytes
Research output: Contribution to conference › Poster › Research
Published