Eric Paul Bennett
Associate Professor
Section 03 - Radiology
Nørre Allé 20
2200 København N
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cDNA cloning and expression of a novel human UDP-N-acetyl-α-D- galactosamine. Polypeptide N-acetylgalactosaminyltransferase, GalNAc-T3
Bennett, Eric Paul, Hassan, H. & Clausen, Henrik, 5 Aug 1996, In: Journal of Biological Chemistry. 271, 29, p. 17006-17012 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Tumor-associated Tn-MUC1 glycoform is internalized through the macrophage galactose-type C-type lectin and delivered to the HLA class I and II compartments in dendritic cells
Napoletano, C., Rughetti, A., Agervig Tarp, M. P., Coleman, J., Bennett, Eric Paul, Picco, G., Sale, P., Denda-Nagai, K., Irimura, T., Mandel, Ulla, Clausen, Henrik, Frati, L., Taylor-Papadimitriou, J., Burchell, J. & Nuti, M., 2007, In: Cancer Research. 67, 17, p. 8358-67 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Toward stable genetic engineering of human o-glycosylation in plants
Yang, Z., Bennett, Eric Paul, Jørgensen, Bodil, Drew, D. P., Arigi, E. A., Mandel, Ulla, Ulvskov, Peter, Levery, S. B., Clausen, Henrik & Petersen, Bent L, 2012, In: Plant Physiology. 160, 1, p. 450-463 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The origin and function of platelet glycosyltransferases
Wandall, Hans H., Rumjantseva, V., Sørensen, A. L. T., Patel-Hett, S., Josefsson, E. C., Bennett, Eric Paul, Italiano, J. E., Clausen, Henrik, Hartwig, J. H. & Hoffmeister, K. M., 19 Jul 2012, In: Blood. 120, 3, p. 626-635 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The lectin domains of polypeptide GalNAc-transferases exhibit carbohydrate-binding specificity for GalNAc: lectin binding to GalNAc-glycopeptide substrates is required for high density GalNAc-O-glycosylation
Wandall, Hans H., Irazoqui, F., Tarp, M. A., Bennett, Eric Paul, Mandel, Ulla, Takeuchi, H., Kato, K., Irimura, T., Suryanarayanan, G., Hollingsworth, M. A. & Clausen, Henrik, 2007, In: Glycobiology. 17, 4, p. 374-87 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The lectin domain of UDP-N-acetyl-D-galactosamine: Polypeptide N-acetylgalactosaminyltransferase-T4 directs its glycopeptide specificities
Hassan, H. S., Reis, C. A., Bennett, Eric Paul, Mirgorodskaya, E., Roepstorff, Hollingsworth, M. A., Burchell, J., Taylor-Papadimitriou, J. & Clausen, Henrik, 2000, In: Journal of Biological Chemistry. 275, p. 38197-38205Research output: Contribution to journal › Journal article › Research › peer-review
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The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells
Tian, W., Ye, Z., Wang, S., Schulz, M. A., Van Coillie, Julie, Sun, L., Chen, Yen-Hsi, Narimatsu, Yoshiki, Hansen, Lars, Kristensen, C., Mandel, Ulla, Bennett, Eric Paul, Jabbarzadeh-Tabrizi, S., Schiffmann, R., Shen, J., Vakhrushev, Sergey, Clausen, Henrik & Yang, Zhang, 2019, In: Nature Communications. 10, 13 p., 1785.Research output: Contribution to journal › Journal article › Research › peer-review
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The VTI1A-TCF4 colon cancer fusion protein is a dominant negative regulator of Wnt signaling and is transcriptionally regulated by intestinal homeodomain factor CDX2
Davidsen, J., Larsen, S., Coskun, M., Gögenur, Ismail, Dahlgaard, K., Bennett, Eric Paul & Troelsen, J. T., 2018, In: PLoS ONE. 13, 7, 13 p., e0200215.Research output: Contribution to journal › Journal article › Research › peer-review
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The O-glycomap of lubricin, a novel mucin responsible for joint lubrication, identified by site-specific glycopeptide analysis
Ali, L., Flowers, S. A., Jin, C., Bennett, Eric Paul, Ekwall, A. K. H. & Karlsson, N. G., 2014, In: Molecular and Cellular Proteomics. 13, 12, p. 3396-3409 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The GalNAc-type O-glycoproteome of CHO cells characterized by the SimpleCell strategy
Yang, Zhang, Halim, Adnan, Narimatsu, Yoshiki, Joshi, Hiren Jitendra, Steentoft, C., Schjoldager, Katrine Ter-Borch Gram, Schulz, M. A., Sealover, N. R., Kayser, K. J., Bennett, Eric Paul, Levery, S. B., Vakhrushev, Sergey & Clausen, Henrik, Dec 2014, In: Molecular & Cellular Proteomics. 13, 12, p. 3224-3235 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The GAGOme: a cell-based library of displayed glycosaminoglycans
Chen, Yen-Hsi, Narimatsu, Yoshiki, Clausen, Thomas Mandel, Gomes, C., Karlsson, R., Steentoft, C., Spliid, C. B., Gustavsson, Tobias, Salanti, Ali, Persson, A., Malmström, A., Willén, D., Ellervik, U., Bennett, Eric Paul, Mao, Y., Clausen, Henrik & Yang, Zhang, 2018, In: Nature Methods. 15, 11, p. 881-888Research output: Contribution to journal › Journal article › Research › peer-review
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Substrate specificities of three members of the human UDP-N-acetyl-alpha-D-galactosamine:Polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1, -T2, and -T3.
Wandall, Hans H., Hassan, H., Mirgorodskaya, E., Kristensen, A. K., Roepstorff, P., Bennett, Eric Paul, Nielsen, P. A., Hollingsworth, M. A., Burchell, J., Taylor-Papadimitriou, J. & Clausen, Henrik, 1997, In: Journal of Biological Chemistry. 272, 38, p. 23503-14 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structural analysis of peptide substrates for mucin-type 0- glycosylation
Kinarsky, L., Nomoto, M., Ikematsu, Y., Hassan, H. S., Bennett, Eric Paul, Cerny, R. L., Clausen, Henrik, Hollingsworth, M. A. & Sherman, S., 1998, In: Biochemistry. 37, p. 12811-12817Research output: Contribution to journal › Journal article › Research › peer-review
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Structural analysis of a GalNAc-T2 mutant reveals an induced-fit catalytic mechanism for GalNAc-Ts
de Las Rivas, M., Coelho, H., Diniz, A., Lira-Navarrete, E., Compañón, I., Jiménez-Barbero, J., Schjoldager, Katrine Ter-Borch Gram, Bennett, Eric Paul, Vakhrushev, Sergey, Clausen, Henrik, Corzana, F., Marcelo, F. & Hurtado-Guerrero, R., 2018, In: Chemistry: A European Journal. 24, 33, p. 8382-8392Research output: Contribution to journal › Journal article › Research › peer-review
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Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions
Wang, S., Mao, Y., Narimatsu, Y., Ye, Z., Tian, W., Goth, C. K., Lira-Navarrete, E., Pedersen, N. B., Benito-Vicente, A., Martin, C., Uribe, K. B., Hurtado-Guerrero, R., Christoffersen, C., Seidah, N. G., Nielsen, R., Christensen, E. I., Hansen, L., Bennett, E. P., Vakhrushev, S. Y., Schjoldager, K. T. & 1 others, , 2018, In: The Journal of Biological Chemistry. 293, 19, p. 7408 –7422Research output: Contribution to journal › Journal article › Research › peer-review
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Site-specific O-Glycosylation on the MUC2 Mucin Protein Inhibits Cleavage by the Porphyromonas gingivalis Secreted Cysteine Protease (RgpB)
van der Post, S., Subramani, D. B., Bäckström, M., Johansson, M. E. V., Vester-Christensen, M. B., Mandel, Ulla, Bennett, Eric Paul, Clausen, Henrik, Dahlén, G., Sroka, A., Potempa, J. & Hansson, G. C., 17 May 2013, In: The Journal of Biological Chemistry. 288, 20, p. 14636-46 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Seromic profiling of colorectal cancer patients with novel glycopeptide microarray
Pedersen, J. W., Blixt, O., Bennett, Eric Paul, Tarp, M. A., Dar, I., Mandel, Ulla, Poulsen, Steen Seier, Pedersen, Anders Elm, Rasmussen, S., Jess, P., Clausen, Henrik & Wandall, Hans H., 15 Apr 2011, In: International Journal of Cancer. 128, 8, p. 1860-71 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ST6GalNAc-I controls expression of sialyl-Tn antigen in gastrointestinal tissues
Marcos, N. T., Bennett, Eric Paul, Gomes, J., Magalhaes, A., Gomes, C., David, L., Dar, I., Jeanneau, C., Defrees, S., Krustrup, D., Vogel, Lotte, Kure, E. H., Burchell, J., Taylor-Papadimitriou, J., Clausen, Henrik, Mandel, Ulla & Reis, C. A., 1 Jun 2011, In: Frontiers in Bioscience (Elite Edition). 3, p. 1443-55 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rescue of Drosophila Melanogaster l(2)35Aa lethality is only mediated by polypeptide GalNAc-transferase pgant35A, but not by the evolutionary conserved human ortholog GalNAc-transferase-T11
Bennett, Eric Paul, Chen, Y., Schwientek, T., Mandel, Ulla, Schjoldager, Katrine Ter-Borch Gram, Cohen, S. M. & Clausen, Henrik, 2010, In: Glycoconjugate Journal. 27, 4, p. 435-44 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Recombinant tumor-axxociated MUC1 glycoprotein impairs the differentiation and function of dendritic cells
Rughetti, A., Pellicciotta, I., Biffoni, M., Bakstrom, M., Link, T., Bennett, Eric Paul, Clausen, Henrik, Noll, T., Hansson, G. C., Burchell, J. M., Frati, L., Taylor-Papadimitriou, J. & Nuti, M., 2006, In: Journal of Immunology. 174, p. 7764-7772Research output: Contribution to journal › Journal article › Research › peer-review
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Purification and cDNA cloning of a human UDP-N-acetyl-a-D-galactosamine: Polypeptide N-Acetylgalctosaminyltransferase
White, T., Bennett, Eric Paul, Takio, K., Sørensen, T., Bonding, N. & Clausen, H., 1995, In: Journal of Biological Chemistry. 270, p. 24156-24165Research output: Contribution to journal › Journal article › Research › peer-review
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Probing the contribution of individual polypeptide GalNAc-transferase isoforms to the O-glycoproteome by inducible expression in isogenic cell lines
Hintze, John, Ye, Z., Narimatsu, Yoshiki, Madsen, Thomas Daugbjerg, Joshi, Hiren Jitendra, Goth, C. K., Linstedt, A., Bachert, C., Mandel, Ulla, Bennett, Eric Paul, Vakhrushev, Sergey & Schjoldager, Katrine Ter-Borch Gram, 2018, In: The Journal of Biological Chemistry. 293, 49, p. 19064-19077 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Probing polypeptide GalNAc-transferase isoform substrate specificities by in vitro analysis
Kong, Y., Joshi, Hiren Jitendra, Schjoldager, Katrine Ter-Borch Gram, Madsen, Thomas Daugbjerg, Gerken, T. A., Vester-Christensen, M. B., Wandall, Hans H., Bennett, Eric Paul, Levery, S. B., Vakhrushev, Sergey & Clausen, Henrik, Jan 2015, In: Glycobiology. 25, 1, p. 55-65 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Probing isoform-specific functions of polypeptide GalNAc-transferases using zinc finger nuclease glycoengineered SimpleCells
Schjoldager, Katrine Ter-Borch Gram, Vakhrushev, Sergey, Kong, Y., Steentoft, C., Nudelman, A. S., Pedersen, N. B., Wandall, Hans H., Mandel, Ulla, Bennett, Eric Paul, Levery, S. B. & Clausen, Henrik, Jun 2012, In: Proceedings of the National Academy of Sciences USA (PNAS). 109, 25, p. 9893-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology
Steentoft, C., Vakhrushev, Sergey, Joshi, Hiren Jitendra, Kong, Y., Vester-Christensen, M. B., Schjoldager, Katrine Ter-Borch Gram, Lavrsen, K., Dabelsteen, Sally, Pedersen, N. B., da Silva, L. P. M., Gupta, R., Bennett, Eric Paul, Mandel, Ulla, Brunak, Søren, Wandall, Hans H., Levery, S. B. & Clausen, Henrik, 15 May 2013, In: E M B O Journal. 32, 10, p. 1478-1488 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 11788
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Improved CRISPR/Cas9 gene editing by fluorescence activated cell sorting of green fluorescence protein tagged protoplasts
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250
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Precise integration of inducible transcriptional elements (PrIITE) enables absolute control of gene expression
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184
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The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells
Research output: Contribution to journal › Journal article › Research › peer-review
Published