Arne Schousboe

Arne Schousboe

Professor, emeritus

ORCID: 0000-0001-9600-402X

Publication year:
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1 - 100 out of 260Page size: 100
  1. 1984
  2. Published

    GABA INFLUENCES THE ULTRASTRUCTURE COMPOSITION OF CEREBELLAR GRANULE CELLS DURING DEVELOPMENT IN CULTURE

    Hansen, Gert Helge, Meier, E. & Schousboe, Arne, 1984, In: International Journal of Developmental Neuroscience. 2, 3, p. 247-257 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 1985
  4. Published

    Cultured neurons as model systems for biochemical and pharmacological studies on receptors for neurotransmitter amino acids

    Schousboe, Arne, Drejer, J., Hansen, Gert Helge & Meier, E., 1985, In: Developmental Neuroscience. 7, 5-6, p. 252-62 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    THE TROPHIC EFFECT OF GABA ON CEREBELLAR GRANULE CELLS IS MEDIATED BY GABA-RECEPTORS

    Meier, E., Hansen, Gert Helge & Schousboe, Arne, 1985, In: International Journal of Developmental Neuroscience. 3, 4, p. 401-407 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 1987
  7. Published

    Temporal development of GABA agonist induced alterations in ultrastructure and GABA receptor expression in cultured cerebellar granule cells

    Hansen, Gert Helge, Belhage, B., Schousboe, Arne & Meier, E., 1987, In: International Journal of Developmental Neuroscience. 5, 3, p. 263-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 1988
  9. Published

    GABA agonist promoted formation of low affinity GABA receptors on cerebellar granule cells is restricted to early development

    Belhage, B., Hansen, Gert Helge, Schousboe, Arne & Meier, E., 1988, In: International Journal of Developmental Neuroscience. 6, 2, p. 125-8 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Gamma-aminobutyric acid agonist-induced alterations in the ultrastructure of cultured cerebellar granule cells is restricted to early development

    Hansen, Gert Helge, Belhage, B., Schousboe, Arne & Meier, E., 1988, In: Journal of Neurochemistry. 51, 1, p. 243-5 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. 1990
  12. Published

    Effects of inhibitors of protein synthesis and intracellular transport on the gamma-aminobutyric acid agonist-induced functional differentiation of cultured cerebellar granule cells

    Belhage, B., Hansen, Gert Helge, Meier, E. & Schousboe, Arne, 1990, In: Journal of Neurochemistry. 55, 4, p. 1107-13 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    GABA agonist induced changes in ultrastructure and GABA receptor expression in cerebellar granule cells is linked to hyperpolarization of the neurons

    Belhage, B., Hansen, Gert Helge & Schousboe, Arne, 1990, In: International Journal of Developmental Neuroscience. 8, 4, p. 473-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 1991
  15. Published

    Effect of a GABA agonist on the expression and distribution of GABAA receptors in the plasma membrane of cultured cerebellar granule cells: an immunocytochemical study

    Hansen, Gert Helge, Belhage, B. & Schousboe, Arne, 1991, In: Neuroscience Letters. 124, 2, p. 162-5 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Light and electron microscopic localization of GABAA-receptors on cultured cerebellar granule cells and astrocytes using immunohistochemical techniques

    Hansen, Gert Helge, Hösli, E., Belhage, B., Schousboe, Arne & Hösli, L., 1991, In: Neurochemical Research. 16, 3, p. 341-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Parallel expression of synaptophysin and evoked neurotransmitter release during development of cultured neurons

    Ehrhart-Bornstein, M., Treiman, M., Hansen, Gert Helge, Schousboe, Arne, Thorn, N. A. & Frandsen, A., 1991, In: International Journal of Developmental Neuroscience. 9, 5, p. 463-71 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Effect of phenylsuccinate on potassium- and ischemia-induced release of glutamate in rat hippocampus monitored by microdialysis

    Christensen, T., Bruhn, T., Diemer, N. H. & Schousboe, Arne, 16 Dec 1991, In: Neuroscience Letters. 134, 1, p. 71-74 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. 1992
  20. Published

    3H-D-aspartate release from cerebellar granule neurons is differentially regulated by glutamate- and K(+)-stimulation

    Belhage, B., Rehder, V., Hansen, Gert Helge, Kater, S. B. & Schousboe, Arne, 1992, In: Journal of Neuroscience Research. 33, 3, p. 436-44 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    First direct electron microscopic visualization of a tight spatial coupling between GABAA-receptors and voltage-sensitive calcium channels

    Hansen, Gert Helge, Belhage, B. & Schousboe, Arne, 1992, In: Neuroscience Letters. 137, 1, p. 14-8 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Stereoselective effects of AMOA on non-NMDA receptors expressed in Xenopus oocytes

    Wahl, P., Nielsen, Birgitte, Krogsgaard-Larsen, Povl, Hansen, J. J., Schousboe, Arne & Miledi, R., Nov 1992, In: Journal of Neuroscience Research. 33, 3, p. 392-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. 1993
  24. Published

    Characterization of NCAM diversity in cultured neurons

    Gegelashvili, G., Andersson, A., Schousboe, Arne & Bock, E., 1993, In: FEBS Letters. 324, p. 337-340

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Cyclic AMP regulates NCAM expression and phosphorylation in cultures mouse astrocytes

    Gegelashvili, G., Andersson, A., Schousboe, Arne & Bock, E., 1993, In: European Journal of Cell Biology. 62, p. 343-351

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Depletion of polyamines prevents the neurotrophic activity of the GABA-agonist THIP in cultured rat cerebellar granule cells

    Abraham, J. H., Hansen, Gert Helge, Seiler, N. & Schousboe, Arne, 1993, In: Neurochemical Research. 18, 2, p. 153-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Depolarization by K+ and glutamate activates different neurotransmitter release mechanisms in GABAergic neurons: vesicular versus non-vesicular release of GABA

    Belhage, B., Hansen, Gert Helge & Schousboe, Arne, 1993, In: Neuroscience. 54, 4, p. 1019-34 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. 1994
  29. Published

    GABAA receptor agonists, partial agonists, and antagonists. Design and therapeutic prospects

    Krogsgaard-Larsen, Povl, Frølund, Bente, Jørgensen, Flemming Steen & Schousboe, Arne, 1994, In: Journal of Medicinal Chemistry. 37, 16, p. 2489-505 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. 1995
  31. Published

    Differential distribution of GABAA receptor subunits in soma and processes of cerebellar granule cells: effects of maturation and a GABA agonist

    Elster, L., Hansen, Gert Helge, Belhage, B., Fritschy, J. M., Möhler, H. & Schousboe, Arne, 1995, In: International Journal of Developmental Neuroscience. 13, 5, p. 417-28 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. 1997
  33. Published

    Characterization of microwell cultures of dissociated brain tissue for studies of cell-cell interactions

    Maar, T. E., Rønn, L. C. B., Bock, E., Berezin, V., Moran, J., Pasantes-Moralez, H. & Schousboe, Arne, 1997, In: Journal of Neuroscience Research. 47, p. 163-172

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Comparison of the agonist binding site of homomeric, heteromeric, and chimeric GluR1(o) and GluR3(o) AMPA receptors

    Banke, T. G., Schousboe, Arne, Pickering, D. S. & Pickering, D., 1997, In: Journal of Neuroscience Research. 49, 2, p. 176-85 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Expression of the GABA(A) receptor alpha6 subunit in cultured cerebellar granule cells is developmentally regulated by activation of GABA(A) receptors

    Carlson, B. X., Belhage, B., Hansen, Gert Helge, Elster, L., Olsen, R. W. & Schousboe, Arne, 1997, In: Journal of Neuroscience Research. 50, 6, p. 1053-62 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Prediction of teratogenic potency of valproate analogues using cerebellar aggregation cultures

    Maar, T. E., Ellerbock, U., Bock, E., Nau, H., Schousboe, Arne & Berezin, V., 1997, In: Toxicology. 116, p. 159-168

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    The First Immunoglodulin-like NCAM Domain is Invelved in both Double Reciprocal Interaction with the Second Ig-like NCAM Domain and in Heparin Binding

    Kiselyov, V. V., Berezin, V., Maar, T., Soroka, V., Edvardsen, K., Schousboe, Arne & Bock, E., 1997, In: Journal of Biological Chemistry. 272, p. 10125-10134

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Characterization of glutamate-induced formation of N- acylphosphatidylethanolamine and N-acylethanolamine in cultured neocortical neurons

    Hansen, Harald S., Lauritzen, Lotte, Strand, A. M., Vinggaard, A. M., Frandsen, Aase & Schousboe, Arne, 1 Aug 1997, In: Journal of Neurochemistry. 69, 2, p. 753-761 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. 1998
  40. Published

    AMPA receptor mediated excitotoxicity in neocortical neurons is developmentally regulated and dependent upon receptor desensitization

    Jensen, J. B., Schousboe, Arne, Pickering, Darryl S & Pickering, Darryl S, 1998, In: Neurochemistry International. 32, 5-6, p. 505-13 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Cell proliferation, migration and CAM-dependent neurite outgrowth as developmental in vitro endpoints for screening teratogenic potential: Application to valproic acid and related analogues of .....

    Bacon, C. L., Berezin, V., Bode, G., Bock, E., Bojic, U., Doherty, P., Edvardsen, K., Ehlers, K., Ellerbeck, U., Julien, P., Kawa, A., Maar, T., Nau, H., Pirovano, R., Regan, C., Schousboe, Arne, Spezia, F., Walsh, F. S. & Williams, E. J., 1998, In: Toxicology in Vitro. 12, p. 101-109

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Development of calcium-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in cultured neocortical neurons visualized by cobalt staining

    Jensen, J. B., Schousboe, Arne, Pickering, Darryl S & Pickering, Darryl S, 1998, In: Journal of Neuroscience Research. 54, 2, p. 273-81 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Effects of gamma-aminobutyric acid (GABA) on synaptogenesis and synaptic function

    Belhage, B., Hansen, Gert Helge, Elster, L. & Schousboe, Arne, 1998, In: Perspectives of Developmental Neurobiology. 5, 2-3, p. 235-46 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Effects of taurine depletion on cell migration and NCAM expression in cultures of dissociated mouse cerebellum and N2A cells

    Maar, T. E., Lund, Trine Meldgaard, Gegelashvili, G., Hartmann-Petersen, Rasmus, Moran, M. J., Pasantes-Morales, H., Berezin, V., Bock, E. & Schousboe, Arne, 1998, In: Amino Acids. 15, 1, p. 77-88 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Pharmacological properties of homomeric and heteromeric GluR1o and GluR3o receptors

    Nielsen, B. S., Banke, T. G., Schousboe, Arne & Pickering, Darryl S, 1998, In: European Journal of Pharmacology. 360, 2-3, p. 227-38 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Spectral components of cytosolic [Ca2+] spiking in neurons

    Kardos, J., Szilágyi, N., Juhász, G., Belhage, B. & Schousboe, Arne, 1998, In: NeuroReport. 9, 4, p. 721-4 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Functional properties of glycine receptors expressed in primary cultures of mouse cerebellar granule cells

    Elster, L., Banke, T., Kristiansen, Uffe, Schousboe, Arne & Wahl, P., May 1998, In: Neuroscience. 84, 2, p. 519-28 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. 1999
  49. Published

    Action of bicyclic isoxazole GABA analogues on GABA transporters and its relation to anticonvulsant activity

    Bolvig, T., Larsson, O. M., Pickering, Darryl S, Nelson, N., Falch, E., Krogsgaard-Larsen, Povl, Schousboe, Arne & Pickering, Darryl S, 1999, In: European Journal of Pharmacology. 375, 1-3, p. 367-74 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Differential localization of voltage-gated calcium channels in neurites and somata of cultured neocortical neurons.

    Timmermann, D., Lund, Trine Meldgaard, Belhage, B. & Schousboe, Arne, 1999, In: Journal of Neurochemistry. 73, Suppl, p. 127 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  51. Published

    Role of desensitization and subunit expression for kainate receptor-mediated neurotoxicity in murine neocortical cultures

    Jensen, J. B., Schousboe, Arne, Pickering, Darryl S & Pickering, Darryl S, 1999, In: Journal of Neuroscience Research. 55, 2, p. 208-17 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Selective Inhibitors of Glial GABA Uptake: Synthesis, Absolute Stereochemistry, and Pharmacology of the Enantiomers of 3-Hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazole (exo-THPO) and Analogues

    Falch, E., Frølund, Bente, Perregaard, Sanchez, C., Søkilde, B., Buur, A., Hansen, A., Frydenvang, Karla Andrea, Brehm, L., Bolvig, T., Larsson, O. M., Schousboe, Arne & Krogsgaard-Larsen, Povl, 1999, In: Journal of Medicinal Chemistry. 42, p. 5402–5414

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Formation of N-acyl-phosphatidylethanolamine and N-acylethanolamine (including anandamide) during glutamate-induced neurotoxicity

    Hansen, Harald S., Moesgaard, B., Hansen, H. H., Schousboe, Arne & Petersen, G., 1 Jan 1999, In: Lipids. 34, 6 SUPPL.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. 2000
  55. Published

    A single glycine residue at the entrance to the first membrane-spanning domain of the γ-aminobutyric acid type a receptor β2 subunit affects allosteric sensitivity to GABA and anesthetics

    Carlson, B. X., Engblom, A. C., Kristiansen, Uffe, Schousboe, Arne & Olsen, R. W., 2000, In: Molecular Pharmacology. 57, 3, p. 474-484 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Agonist discrimination between AMPA receptor subtypes

    Coquelle, T., Christensen, J. K., Banke, T. G., Madsen, U., Schousboe, Arne & Pickering, Darryl S, 2000, In: NeuroReport. 11, 12, p. 2643-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Depolarization-induced release of [(3)H]D-aspartate from GABAergic neurons caused by reversal of glutamate transporters

    Jensen, J. B., Pickering, Darryl S, Schousboe, Arne & Pickering, Darryl S, 2000, In: International Journal of Developmental Neuroscience. 18, 2-3, p. 309-15 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Determination of the phospholipid precursor of anandamide and other N- acylethanolamine phospholipids before and after sodium azide-induced toxicity in cultured neocortical neurons

    Hansen, H. H., Schousboe, Arne, Hansen, Harald S. & Hansen, S. H., 1 Jan 2000, In: Journal of Neurochemistry. 75, 2, p. 861-871 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. 2001
  60. Published

    Characterization of the 1H-cyclopentapyrimidine-2,4(1H,3H)-dione derivative (S)-CPW399 as a novel, potent, and subtype-selective AMPA receptor full agonist with partial desensitization properties

    Campiani, G., Morelli, E., Nacci, V., Fattorusso, C., Ramunno, A., Novellino, E., Greenwood, J., Liljefors, T., Griffiths, R., Sinclair, C., Reavy, H., Kristensen, A. S., Pickering, Darryl S, Schousboe, Arne, Cagnotto, A., Fumagalli, E., Mennini, T. & Pickering, Darryl S, 2001, In: Journal of Medicinal Chemistry. 44, 26, p. 4501-4 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Identification of amino acid residues in GluR1 responsible for ligand binding and desensitization

    Banke, T. G., Greenwood, J. R., Christensen, J. K., Liljefors, T., Traynelis, S. F., Schousboe, Arne, Pickering, D. S. & Pickering, D., 2001, In: Journal of Neuroscience. 21, 9, p. 3052-62 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Localization and pharmacological characterization of voltage dependent calcium channels in cultured neocortical neurons

    Timmermann, D. B., Lund, Trine Meldgaard, Belhage, B. & Schousboe, Arne, 2001, In: International Journal of Developmental Neuroscience. 19, 1, p. 1-10 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Molecular determinants of desensitization and assembly of the chimeric GABA(A) receptor subunits (alpha1/gamma2) and (gamma2/alpha1) in combinations with beta2 and gamma2

    Elster, L., Kristiansen, Uffe, Pickering, Darryl S, Olsen, R. W. & Schousboe, Arne, 2001, In: Neurochemistry International. 38, 7, p. 581-92 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Role of GluR2 expression in AMPA-induced toxicity in cultured murine cerebral cortical neurons

    Jensen, J. B., Lund, Trine Meldgaard, Timmermann, D. B., Schousboe, Arne & Pickering, Darryl S, 2001, In: Journal of Neuroscience Research. 65, 3, p. 267-277 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. 2002
  66. Published

    Correlation between Anticonvulsant Activity and Inhibitory Action on Glial -Aminobutyric Acid Uptake of the Highly Selective Mouse -Aminobutyric Acid Transporter 1 Inhibitor 3-Hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazole and Its N-Alkylated Analogs

    White, S., Sarup, A., Bolvig, T., Petersen, G., Nelson, N., Pickering, Darryl S, Larsson, O. M., Frølund, Bente, Falch, E., Krogsgaard-Larsen, Povl & Schousboe, Arne, 2002, In: Journal of Pharmacology and Experimental Therapeutics. 302, p. 636–644

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Point mutation in the first transmembrane region of the β2 subunit of the γ-aminobutyric acid type A receptor alters desensitization kinetics of γ-aminobutyric acid- and anesthetic-induced channel gating

    Christine Engblom, A., Carlson, B. X., Olsen, R. W., Schousboe, Arne & Kristiansen, Uffe, 17 May 2002, In: Journal of Biological Chemistry. 277, 20, p. 17438-17447 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. 2003
  69. Published

    Design, synthesis, and pharmacology of a highly subtype-selective GluR1/2 agonist, (RS)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid (Cl-HIBO)

    Bjerrum, E. J., Kristensen, Anders Skov, Pickering, D. S., Greenwood, J. R., Nielsen, Birgitte, Liljefors, T., Schousboe, Arne, Bräuner, Hans, Madsen, Ulf & Pickering, Darryl S, 2003, In: Journal of Medicinal Chemistry. 46, 11, p. 2246-9 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Effects of 3-hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazol (exo-THPO) and its N-substituted analogs on GABA transport in cultured neurons and astrocytes and by the four cloned mouse GABA transporters

    sarup, A., Larsson, O. M., Bolvig, T., Frølund, Bente, Krogsgaard-Larsen, Povl & Schousboe, Arne, 2003, In: Neurochemistry International. 43, p. 445–451

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Characterization of depolarization-coupled release of glutamate from cultured mouse cerebellar granule cells using DL-threo-beta-benzyloxyaspartate (DL-TBOA) to distinguish between the vesicular and cytoplasmic pools

    Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 14 May 2003, In: Neurochemistry International. 43, 4-5, p. 417-24 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. 2004
  73. Published

    On the neurotoxicity of glutaric, 3-hydroxyglutaric, and trans-glutaconic acids in glutaric acidemia type 1

    Lund, Trine Meldgaard, Christensen, E., Kristensen, Anders Skov, Schousboe, Arne & Lund, Allan Meldgaard, 2004, In: Journal of Neuroscience Research. 77, 1, p. 143-7 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Role of astrocytes in depolarization-coupled release of glutamate in cerebellar cultures

    Bak, Lasse Kristoffer, Waagepetersen, Helle S. & Schousboe, Arne, Jan 2004, In: Neurochemical Research. 29, 1, p. 257-65 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Role of astrocytic transport processes in glutamatergic and GABAergic neurotransmission

    Schousboe, Arne, Sarup, A., Bak, Lasse Kristoffer, Waagepetersen, Helle S. & Larsson, O. M., Sep 2004, In: Neurochemistry International. 45, 4, p. 521-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Activity of the lactate-alanine shuttle is independent of glutamate-glutamine cycle activity in cerebellar neuronal-astrocytic cultures

    Bak, Lasse Kristoffer, Sickmann, H. M., Schousboe, Arne & Waagepetersen, Helle S., 4 Dec 2004, In: Journal of Neuroscience Research. 79, 1-2, p. 88-96 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. 2005
  78. Published

    Astrocyte glycogen metabolism is required for neural activity during aglycemia or intense stimulation in mouse white matter

    Brown, A. M., Sickmann, H. M., Fosgerau, K., Lund, Trine Meldgaard, Schousboe, Arne, Waagepetersen, Helle S. & Ransom, B. R., 2005, In: Journal of Neuroscience Research. 79, 1-2, p. 74-80 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Differential effects of two GABA transport inhibitors, tiagabine and EF-1502, on phenytoin-resistant spontaneous bursting in the entorhinal cortex of slices from kainic acid treated rats

    Smith-Yockman, M., Saunders, G., Wilcox, K., Clausen, Rasmus Prætorius, Frølund, Bente, Larsson, O., Schousboe, Arne & White, H., 2005, In: Epilepsia. 46, p. 188-188

    Research output: Contribution to journal › Conference abstract in journal › Research

  80. Published

    Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP

    Nielsen, B. B., Pickering, Darryl S, Greenwood, J. R., Brehm, L., Gajhede, Michael, Schousboe, Arne & Kastrup, Jette Sandholm Jensen, 2005, In: FEBS Journal. 272, 7, p. 1639-48 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    First Demonstration of a Functional Role for CNS Betaine/GABA Transporter (mGAT2) Based on Synergistic Anticonvulsant Action Among Inhibitors of mGAT1 and mGAT2

    White, S., Watson, W. P., Hansen, S. L., Slough, S., Perregård, J., Sarup, A., Bolvig, T., Petersen, G., Larsson, O. M., Clausen, Rasmus Prætorius, Frølund, Bente, Falch, E., Krogsgaard-Larsen, Povl & Schousboe, Arne, 2005, In: The Journal of Pharmacology and Experimental Therapeutics. 312, p. 866–874

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Lipid raft localization of GABA A receptor and Na+, K+-ATPase in discrete microdomain clusters in rat cerebellar granule cells

    Dalskov, S., Immerdal, L., Niels-Christiansen, L. W., Hansen, Gert Helge, Schousboe, Arne & Danielsen, E. M., 2005, In: Neurochemistry International. 46, 6, p. 489-99 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Selective inhibitors of GABA uptake: synthesis and molecular pharmacology of 4-N-methylamino- 4,5,6,7-tetrahydrobenzo[d]isoxazol-3-ol analogues

    Clausen, Rasmus Prætorius, Moltzen, E. K., Perregaard, J., Lenz, S., Sanchez, C., Falch, E., Frølund, Bente, Bolvig, T., Sarup, A., Larsson, O. M., Schousboe, Arne & Krogsgaard-Larsen, Povl, 2005, In: Bioorganic & Medicinal Chemistry. 13, p. 895–908

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Tyr702 is an important determinant of agonist binding and domain closure of the ligand-binding core of GluR2

    Frandsen, A., Pickering, Darryl S, Vestergaard, Bente, Kasper, C., Nielsen, B. B., Greenwood, J. R., Campiani, G., Fattorusso, C., Gajhede, Michael, Schousboe, Arne & Kastrup, Jette Sandholm Jensen, 2005, In: Molecular Pharmacology. 67, 3, p. 703-13 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Design, synthesis, and characterisation of selective GABA transport inhibitors

    Clausen, Rasmus Prætorius, Moltzen, E., Perregaard, J., Lenz, S., Sanchez, S., Frølund, Bente, Bolvig, T., Sarup, A., Larsson, O., White, H., Schousboe, Arne & Krogsgaard-Larsen, Povl, Aug 2005, In: Journal of Neurochemistry. 94, p. 150-150

    Research output: Contribution to journal › Conference abstract in journal › Research

  86. Published

    Effect of tiagabine and EF1502 on phenytoin-resistant spontaneous bursts in the entorhinal cortex of slices from kainic acid-treated rats

    Smith-Yockman, M., Saunders, G., Wilcox, K., Larsson, O., Clausen, Rasmus Prætorius, Frølund, Bente, Schousboe, Arne & White, H., Aug 2005, In: Journal of Neurochemistry. 94, p. 256-256

    Research output: Contribution to journal › Conference abstract in journal › Research

  87. 2006
  88. Published

    A novel selective γ-aminobutyric acid transport inhibitor demonstrates a functional role for GABA transporter subtype GAT2/BGT-1 in the CNS

    Frølund, Bente, Clausen, Rasmus Prætorius, Larsson, O. M., Schousboe, Arne, Krogsgaard-Larsen, Povl & White, H. S., 2006, In: Neurochemistry International. 48, p. 637–642

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Effect of topiramate and dBcAMP on expression of the glutamate transporters GLAST and GLT-1 in astrocytes cultured separately, or together with neurons

    Poulsen, C. F., Schousboe, E. I., Sarup, A., White, H. S. & Schousboe, Arne, 2006, In: Neurochemistry International. 48, Sp. Iss. SI 6-7, p. 657-661 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Functional and Pharmacological Aspects of GABA Transporters

    Madsen, K., White, S. H., Clausen, Rasmus Prætorius, Larsson, O. M., Frølund, Bente, Krogsgaard-Larsen, Povl & Schousboe, Arne, 2006, Handbook of Neurochemistry and Molecular neurobiology. p. 1-17

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  91. Published

    Structure-Activity Relationships of Selective GABA Uptake Inhibitors

    Høg, S., Greenwood, J., Madsen, K. B., Larsson, O. M., Frølund, Bente, Schousboe, Arne, Krogsgaard-Larsen, Povl & Clausen, Rasmus Prætorius, 2006, In: Current Topics in Medicinal Chemistry. 6, 17, p. 1861–1882

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Structure–Activity Relationship and Pharmacology of γ‐Aminobutyric Acid Transport Inhibitor

    Clausen, Rasmus Prætorius, Madsen, K., Larsson, O. M., Frølund, Bente, Krogsgaard-Larsen, Povl & Schousboe, Arne, 2006, GABA. Enna, S. (ed.). Vol. 54. p. 265–284 (Advances in Pharmacology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  93. Published

    The structure of a mixed GluR2 ligand-binding core dimer in complex with (S)-glutamate and the antagonist (S)-NS1209

    Kasper, C., Pickering, Darryl S, Mirza, Osman Asghar, Olsen, L., Kristensen, Anders Skov, Greenwood, J. R., Liljefors, T., Schousboe, Arne, Wätjen, F., Gajhede, Michael, Sigurskjold, B. W. & Kastrup, Jette Sandholm Jensen, 2006, In: Journal of Molecular Biology. 357, 4, p. 1184-201 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Demonstration of extensive GABA synthesis in the small population of GAD positive neurons in cerebellar cultures by the use of pharmacological tools

    Sonnewald, U., Kortner, T. M., Qu, H., Olstad, E., Suñol, C., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 7 Mar 2006, In: Neurochemistry International. 48, 6-7, p. 572-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Neurotransmitter transporters: molecular function of important drug targets

    Gether, Ulrik, Andersen, P. H., Larsson, O. M. & Schousboe, Arne, Jul 2006, In: Trends in Pharmacological Sciences. 27, 7, p. 375-83 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer

    Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., Aug 2006, In: Journal of Neurochemistry. 98, 3, p. 641-53 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Glucose is necessary to maintain neurotransmitter homeostasis during synaptic activity in cultured glutamatergic neurons

    Bak, Lasse Kristoffer, Schousboe, Arne, Sonnewald, U. & Waagepetersen, Helle S., Oct 2006, In: Journal of Cerebral Blood Flow and Metabolism. 26, 10, p. 1285-97 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Structure-Activity Relationship and Pharmacology of γ-Aminobutyric Acid (GABA) Transport Inhibitors

    Clausen, Rasmus Prætorius, Madsen, K., Larsson, O. M., Frølund, Bente, Krogsgaard-Larsen, Povl & Schousboe, Arne, 1 Dec 2006, GABA. Enna, S. J. (ed.). p. 265-284 20 p. (Advances in Pharmacology, Vol. 54).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  99. 2007
  100. Published

    Actions of toxins on cerebral metabolism at cellular level

    Sonnewald, U., Syversen, T., Schousboe, Arne, Waagepetersen, Helle S. & Aschner, M., 2007, Handbook of Neurochemistry and Molecular Neurobiology: Brain Energetics. Integration of Molecular and Cellular Processes. Lajtha, A., Gibson, G. E. & Dienel, G. A. (eds.). 3rd. ed. ed. Berlin: Springer, Vol. 3. p. 569-585

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  101. Published

    Among the branched-chain amino acids, only valine metabolism is up-regulated in astrocytes during glutamate exposure

    Bak, Lasse Kristoffer, Johansen, M. L., Schousboe, Arne & Waagepetersen, Helle S., 2007, In: Journal of Neuroscience Research. 86, p. 3465-3470

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. Published

    Complex glutamate labeling from [U-13C]glucose or [U-13C]lactate in co-cultures of cerebellar neurons and astrocytes

    Bak, Lasse Kristoffer, Waagepetersen, Helle S., Melø, T. M., Schousboe, Arne & Sonnewald, U., 2007, In: Neurochemical Research. 32, p. 671-680

    Research output: Contribution to journal › Journal article › Research › peer-review

  103. Published

    Energy substrates to support glutamatergic and GABAergic synaptic function: Role of glycogen, glucose and lactate

    Schousboe, Arne, Bak, Lasse Kristoffer, Sickmann, H. M., Sonnewald, U. & Waagepetersen, Helle S., 2007, In: Neurotoxicity Research. 12, 4, p. 263-268

    Research output: Contribution to journal › Journal article › Research › peer-review

  104. Published

    Evidence of Oatp and Mdr1 in cryopreserved rat hepatocytes

    Jørgensen, L., van Beek, J., Lund, S., Schousboe, Arne & Badolo, L., 2007, In: European Journal of Pharmaceutical Sciences. 30, 2, p. 181-189

    Research output: Contribution to journal › Journal article › Research › peer-review

  105. Published

    Functional and pharmacological aspects of GABA transporters

    Madsen, K., White, H. S., Clausen, Rasmus Prætorius, Frølund, Bente, Larsson, O. M., Krogsgaard-Larsen, Povl & Schousboe, Arne, 2007, Handbook of nerochemistry and molecular neurobiology: Neural membranes and transport. Lajtha, A. & Reith, M. E. A. (eds.). 3rd. ed. Berlin: Springer, Vol. 3. p. 285-304

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  106. Published

    GABA transporter localization to lipid raft membrane microdomains in neurons and astrocytes

    Madsen, K. K., Pickering, Darryl S, Hansen, G. H., Danielsen, E. M., Larsson, O. M. & Schousboe, Arne, 2007, In: Journal of Neurochemistry. 102, s1, p. 46

    Research output: Contribution to journal › Conference abstract in journal › Research

  107. Published

    GABA: Homeostatic and pharmacological aspects

    Schousboe, Arne & Waagepetersen, Helle S., 2007, In: Progress in Brain Research. 160, p. 9-19

    Research output: Contribution to journal › Journal article › Research › peer-review

  108. Published

    Glutamine in the central nervous system: function and dysfunction

    Albrecht, J., Sonnewald, U., Waagepetersen, Helle S. & Schousboe, Arne, 2007, In: Frontiers in Bioscience. 12, p. 332-343

    Research output: Contribution to journal › Journal article › Research › peer-review

  109. Published

    Glutamine, glutamate and GABA: metabolic aspects

    Waagepetersen, Helle S., Sonnerwald, U. & Schousboe, Arne, 2007, Handbook of neurochemistry and molecular neurobiology: amino acids and peptides in the nervous system. Lajtha, A., Oja, S. S., Schousboe, A. & Saransaari, P. (eds.). 3rd. ed. Berlin: Springer, p. 1-21

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  110. Published

    One third of glycolytic activity in astrocytes depends on the operation of the glycogen shunt

    Walls, Anne Byriel, Heimbürger, C. M., Sickmann, H. M., Bouman, S. D., Schousboe, Arne & Waagepetersen, Helle S., 2007, In: Journal of Neurochemistry. 102, s1, p. 119

    Research output: Contribution to journal › Conference abstract in journal › Research

  111. Published

    Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: Structures of the ligand-bining core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid

    Hald, H., Naur, P., Pickering, Darryl S, Sprogøe, D., Madsen, Ulf, Timmermann, D. B., Ahring, P. K., Liljefors, T., Schousboe, Arne, Egebjerg, J., Gajhede, Michael & Kastrup, Jette Sandholm Jensen, 2007, In: Journal of Biological Chemistry. 282, 35, p. 25726-25736

    Research output: Contribution to journal › Journal article › Research › peer-review

  112. Published

    The metabolic role of isoleucine in detoxification of ammonia in cultured mouse neurons and astrocytes

    Johansen, M. L., Bak, Lasse Kristoffer, Schousboe, Arne, Iversen, P., Sørensen, M., Keiding, S., Vilstrup, H., Gjedde, A., Ott, P. & Waagepetersen, Helle S., 2007, In: Neurochemistry International. 50, p. 1042-1051

    Research output: Contribution to journal › Journal article › Research › peer-review

  113. Published

    The transcriptome and metabolic gene signature of protoplasmic astrocytes in the adult murine cortex

    Lovatt, D., Sonnewald, U., Waagepetersen, Helle S., Schousboe, Arne, He, W., Lin, J. H., Han, X., Takano, T., Wang, S., Sim, F. J., Goldman, S. A. & Nedergaard, M., 2007, In: Journal of Neuroscience. 27, 45, p. 12255-12266

    Research output: Contribution to journal › Journal article › Research › peer-review

  114. Published

    ß-hydroxybutyrate and glucose metabolism is differently affected by neuronal activity

    Lund, Trine Meldgaard, Clausen, M., Risa, O., Sonnewald, U., Schousboe, Arne & Waagepetersen, Helle S., 2007, In: Journal of Neurochemistry. 102, s1, p. 116

    Research output: Contribution to journal › Conference abstract in journal › Research

  115. Published

    Energy substrates to support glutamatergic and GABAergic synaptic function: role of glycogen, glucose and lactate

    Schousboe, Arne, Bak, Lasse Kristoffer, Sickmann, H. M., Sonnewald, U. & Waagepetersen, Helle S., Dec 2007, In: Neurotoxicity Research. 12, 4, p. 263-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  116. 2008
  117. Published

    1H-cyclopentapyrimidine-2,4(1H,3H)-dione-related ionotropic glutamate receptors ligands. Structure-activity relationships and identification of potent and selective iGluR5 modulators

    Butini, S., Pickering, Darryl S, Morelli, E., Coccone, S. S., Trotta, F., De Angelis, M., Guarino, E., Fiorini, I., Campiani, G., Novellino, E., Schousboe, Arne, Christensen, J. K. & Gemma, S., 2008, In: Journal of Medicinal Chemistry. 51, 20, p. 6614-8

    Research output: Contribution to journal › Journal article › Research › peer-review

  118. Published

    Characterization of 1,4-dideoxy-1,4-imino-d-arabinitol (DAB) as an inhibitor of brain glycogen shunt activity

    Walls, Anne Byriel, Sickmann, H. M., Brown, A., Bouman, S. D., Ransom, B., Schousboe, Arne & Waagepetersen, Helle S., 2008, In: Journal of Neurochemistry. 105, p. 1462-1470

    Research output: Contribution to journal › Journal article › Research › peer-review

  119. Published

    Demonstration of neuron-glia transfer of precursors for Gaba biosynthesis in a co-culture system of dissociated mouse cerebral cortex

    Leke, R., Bak, Lasse Kristoffer, Schousboe, Arne & Waagepetersen, Helle S., 2008, In: Neurochemical Research. 33, 12, p. 2629-2635

    Research output: Contribution to journal › Journal article › Research › peer-review

  120. Published

    GABA Neurotransmission: An overview

    Schousboe, Arne & Waagepetersen, Helle S., 2008, Handbook of Neurochemistry and Molecular Neurobiology: Neurotransmitter Systems. Vizi, E. S. (ed.). The Netherlands: Springer Publishing Company, p. 213-226

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  121. Published

    GABA-transportører: håb om bedre epilepsibehandling

    Madsen, K. K., Clausen, Rasmus Prætorius, Larsson, O. M. & Schousboe, Arne, 2008, In: Lægemiddelforskning. p. 22-24

    Research output: Contribution to journal › Journal article › Communication

  122. Published

    Inhibition of the betaine-GABA transporter (mGAT2/BGT-1) modulates spontaneous electrographic bursting in the medial entorhinal cortex (mEC)

    Smith, M. D., Saunders, G. W., Clausen, Rasmus Prætorius, Frølund, Bente, Krogsgaard-Larsen, Povl, Larsson, O. M., Schousboe, Arne, Wilcox, K. S. & White, H. S., 2008, In: Epilepsy Research. 79, 1, p. 6-13

    Research output: Contribution to journal › Journal article › Research › peer-review

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