Lars Hviid
Professor
Centre for Medical Parasitology
CMP
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-11-TR4
Member of:
SURFACE team
- Published
Unraveling the impact of malaria exposure before birth
Hviid, Lars, 2009, In: PLoS Medicine. 6, 7, p. e1000117Research output: Contribution to journal › Journal article › Research › peer-review
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No sweet deal: the antibody-mediated immune response to malaria
Hviid, Lars, Lopez-Perez, Mary, Larsen, M. D. & Vidarsson, G., 2022, In: Trends in Parasitology. 38, 6, p. 428-434Research output: Contribution to journal › Review › Research › peer-review
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Biochemical characterization, localization and immunostimulating properties of a soluble glycoprotein, Ag1, isolated from in vitro cultures of Plasmodium falciparum
Jakobsen, P. H., Jepsen, S., Riley, E. M., Theander, Thor Grundtvig, Grellier, P., Lihme, A., Hviid, Lars, Dziegiel, Morten Hanefeld & Schrevel, J., 1990, In: Parasitology Reseach. 76, 8, p. 657-61 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased plasma levels of soluble IL-2R are associated with severe Plasmodium falciparum malaria
Jakobsen, P. H., Morris-Jones, S., Theander, Thor Grundtvig, Hviid, Lars, Hansen, M. B., Bendtzen, K., Ridley, R. G. & Greenwood, B. M., 1994, In: Clinical and Experimental Immunology. 96, 1, p. 98-103 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Soluble haemoglobin is a marker of recent Plasmodium falciparum infections
Jakobsen, P. H., Bygbjerg, Ib Christian, Theander, Thor Grundtvig, Hviid, Lars, Fujioka, H., Aikawa, M., Bayoumi, R. A. & Koch, C., 1997, In: Immunology Letters. 59, 1, p. 35-42 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibody reactivities to glutamate-rich peptides of Plasmodium falciparum parasites in humans from areas of different malaria endemicity
Jakobsen, P. H., Theander, Thor Grundtvig, Hviid, Lars, Morris-Jones, S., Jensen, J. B., Bayoumi, R. A., Greenwood, B. M., Bygbjerg, Ib Christian & Heegaard, P. M., 1996, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 104, 10, p. 734-40 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibody responses to Rhoptry-Associated Protein-1 (RAP-1) of Plasmodium falciparum parasites in humans from areas of different malaria endemicity
Jakobsen, P. H., Kurtzhals, Jørgen, Riley, E. M., Hviid, Lars, Theander, Thor Grundtvig, Morris-Jones, S., Jensen, J. B., Bayoumi, R. A., Ridley, R. G. & Greenwood, B. M., 1997, In: Parasite Immunology. 19, 9, p. 387-93 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Specific T-cell recognition of the merozoite proteins rhoptry-associated protein 1 and erythrocyte-binding antigen 1 of Plasmodium falciparum
Jakobsen, P. H., Hviid, Lars, Theander, Thor Grundtvig, Afare, E. A., Ridley, R. G., Heegaard, P. M., Stuber, D., Dalsgaard, K. & Nkrumah, F. K., 1993, In: Infection and Immunity. 61, 1, p. 268-73 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Isolation and characterization of a soluble antigen complex of Plasmodium falciparum with pyrogenic properties
Jakobsen, P. H., Hviid, Lars, Theander, Thor Grundtvig, Riley, E. M., Grellier, P., Bruun, L. S., Dalsgaard, K., Schrevel, J. & Jepsen, S., 1991, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 99, 1, p. 21-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased plasma concentrations of sICAM-1, sVCAM-1 and sELAM-1 in patients with Plasmodium falciparum or P. vivax malaria and association with disease severity
Jakobsen, P. H., Morris-Jones, S., Rønn, A., Hviid, Lars, Theander, Thor Grundtvig, Elhassan, I. M., Bygbjerg, Ib Christian & Greenwood, B. M., 1994, In: Immunology. 83, 4, p. 665-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Anti-phospholipid antibodies in patients with Plasmodium falciparum malaria
Jakobsen, P. H., Morris-Jones, S. D., Hviid, Lars, Theander, Thor Grundtvig, Høier-Madsen, M., Bayoumi, R. A. & Greenwood, B. M., 1993, In: Immunology. 79, 4, p. 653-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Malaria immunology: Targeting the surface of infected erythrocytes
Jensen, Anja Ramstedt (ed.) & Hviid, Lars (ed.), 2022, Humana Press. 796 p. (Methods in Molecular Biology, Vol. 2470).Research output: Book/Report › Book › Research › peer-review
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Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1-based vaccines to prevent it
Jensen, Anja Ramstedt, Adams, Yvonne & Hviid, Lars, 2020, In: Immunological Reviews. 293, 1, p. 230-252Research output: Contribution to journal › Review › Research › peer-review
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Lack of gender-specific antibody recognition of products from domains of a var gene implicated in pregnancy-associated Plasmodium falciparum malaria
Jensen, Anja Ramstedt, Zornig, H. D., Buhmann, Cæcilie Christine Böck, Salanti, Ali, Koram, K. A., Riley, E. M., Theander, Thor Grundtvig, Hviid, Lars & Staalsoe, T., 2003, In: Infection and Immunity. 71, 7, p. 4193-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes
Jensen, Anja Ramstedt, Magistrado, P., Sharp, S., Joergensen, L., Lavstsen, Thomas, Chiucchiuini, A., Salanti, Ali, Vestergaard, L. S., Lusingu, J. P., Hermsen, R., Sauerwein, R., Christensen, J., Nielsen, Morten Agertoug, Hviid, Lars, Sutherland, C., Staalsoe, T. & Theander, Thor Grundtvig, 2004, In: Journal of Experimental Medicine. 199, 9, p. 1179-90 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multiple Plasmodium falciparum erythrocyte membrane protein 1 variants per genome can bind IgM via its Fc fragment Fcμ
Jeppesen, A., Ditlev, S. B., Soroka, V., Stevenson, E. K., Turner, Louise, Dzikowski, R., Hviid, Lars & Barfod, Lea Klingenberg, 2015, In: Infection and Immunity. 83, 10, p. 3972-81 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dansk malariaforskning fra spæd begyndelse til international styrkeposition
Jepsen, M. P. G., Jepsen, S., Kurtzhals, Jørgen & Hviid, Lars, 2017, In: Ugeskrift for Laeger. 179, 20, p. 866-869 V10160756.Research output: Contribution to journal › Journal article › Research › peer-review
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CCR3 expression induced by IL-2 and IL-4 functioning as a death receptor for B cells
Jinquan, T., Jacobi, H. H., Jing, C., Millner, A., Sten, E., Hviid, Lars, Anting, L., Ryder, L. P., Glue, C., Skov, P. S., Jarman, E., Lamberth, K., Malling, H. & Poulsen, Lars K., 2003, In: Journal of Immunology. 171, 4, p. 1722-31 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The kinetics of antibody binding to Plasmodium falciparum VAR2CSA PfEMP1 antigen and modelling of PfEMP1 antigen packing on the membrane knobs
Joergensen, L. M., Salanti, Ali, Dobrilovic, T., Barfod, Lea Klingenberg, Hassenkam, Tue, Theander, Thor Grundtvig, Hviid, Lars & Arnot, D. E., 2010, In: Malaria Journal. 9, 1, p. 100Research output: Contribution to journal › Journal article › Research › peer-review
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Frequency of electrocardiographic alterations and pericardial effusion in patients with uncomplicated malaria
Kaagaard, M. D., Matos, L. O., Holm, A. E., Gomes, L. C., Wegener, A., Lima, K. O., Vieira, I. V. M., de Souza, R. M., Marinho, C. R. F., Hviid, Lars, Vestergaard, L. S., Dominguez, Helena, Biering-Sørensen, Tor, Silvestre, O. M. & Brainin, P., 2022, In: American Journal of Cardiology. 165, p. 116-123Research output: Contribution to journal › Journal article › Research › peer-review
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Aligned hemozoin crystals in curved clusters in malarial red blood cells revealed by nanoprobe X-ray Fe fluorescence and diffraction
Kapishnikov, S., Berthing, T., Hviid, Lars, Dierolf, M., Menzel, A., Pfeiffer, F., Als-Nielsen, Jens & Leiserowitz, L., 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 28, p. 11184-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interferon-¿- and tumour necrosis factor-a-producing cells in humans who are immune to cutaneous leishmaniasis
Kemp, K., Theander, Thor Grundtvig, Hviid, Lars, Garfar, A., Kharazmi, A. & Kemp, M., 1999, In: Scandinavian Journal of Immunology. 49, 6, p. 655-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Leishmania-specific T cells expressing interferon-¿(IFN-¿) and IL-10 upon activation are expanded in individuals cured of visceral leishmaniasis
Kemp, K., Kemp, M., Kharazmi, A., Ismail, A., Kurtzhals, Jørgen, Hviid, Lars & Theander, Thor Grundtvig, 1999, In: Clinical and Experimental Immunology. 116, 3, p. 500-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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West African donors have high percentages of activated cytokine producing T cells that are prone to apoptosis
Kemp, K., Akanmori, B. D. & Hviid, Lars, 2001, In: Clinical and Experimental Immunology. 126, 1, p. 69-75 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cytokine production and apoptosis among T cells from patients under treatment for Plasmodium falciparum malaria
Kemp, K., Akanmori, B. D., Adabayeri, V., Goka, B. Q., Kurtzhals, Jørgen, Behr, C. & Hviid, Lars, 2002, In: Clinical and Experimental Immunology. 127, 1, p. 151-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interferon-¿ production by human T cells and natural killer cells in vitro in response to antigens from the two intracellular pathogens Mycobacterium tuberculosis and Leishmania major
Kemp, K., Hviid, Lars, Kharazmi, A. & Kemp, M., 1997, In: Scandinavian Journal of Immunology. 46, 5, p. 495-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased levels of soluble CD30 in plasma of patients with Plasmodium falciparum malaria
Kemp, K., Kurtzhals, Jørgen, Akanmori, B. D., Adabayeri, V., Goka, B. Q., Behr, C. & Hviid, Lars, 2002, In: Clinical and Vaccine Immunology. 9, 3, p. 720-2 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Acute P. falciparum malaria induces a loss of CD28- T IFN-¿ producing cells
Kemp, K., Akanmori, B. D., Kurtzhals, J. A. L., Adabayeri, V., Goka, B. Q. & Hviid, Lars, 2002, In: Parasite Immunology. 24, 11-12, p. 545-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Activation of human T lymphocytes by Leishmania lipophosphoglycan
Kemp, M., Theander, Thor Grundtvig, Handman, E., Hey, A. S., Kurtzhals, Jørgen, Hviid, Lars, Sørensen, A. L., Were, J. O., Koech, D. K. & Kharazmi, A., 1991, In: Scandinavian Journal of Immunology. 33, 2, p. 219-24 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of IgG with specificity for variant surface antigens expressed by placental Plasmodium falciparum isolates
Khattab, A., Reinhardt, C., Staalsoe, T., Fievet, N., Kremsner, P. G., Deloron, P., Hviid, Lars & Klinkert, M., 2004, In: Malaria Journal. 3, p. 21Research output: Contribution to journal › Journal article › Research › peer-review
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Reversible suppression of bone marrow response to erythropoietin in Plasmodium falciparum malaria
Kurtzhals, Jørgen, Rodrigues, O., Addae, M., Commey, J. O., Nkrumah, F. K. & Hviid, Lars, 1997, In: British Journal of Haematology. 97, 1, p. 169-74 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The importance of strict patient definition in studies of malaria pathogenesis
Kurtzhals, Jørgen, Goka, B. Q., Akanmori, B. D. & Hviid, Lars, 2001, In: Trends in Parasitology. 17, 7, p. 313-4 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased eosinophil activity in acute Plasmodium falciparum infection - association with cerebral malaria
Kurtzhals, Jørgen, Reimert, C. M., Tette, E., Dunyo, S. K., Koram, K. A., Akanmori, B. D., Nkrumah, F. K. & Hviid, Lars, 1998, In: Clinical and Experimental Immunology. 112, 2, p. 303-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Low plasma concentrations of interleukin 10 in severe malarial anaemia compared with cerebral and uncomplicated malaria
Kurtzhals, Jørgen, Adabayeri, V., Goka, B. Q., Akanmori, B. D., Oliver-Commey, J. O., Nkrumah, F. K., Behr, C. & Hviid, Lars, 1998, In: Lancet. 351, 9118, p. 1768-72 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Anaemia caused by asymptomatic Plasmodium falciparum infection in semi-immune African schoolchildren
Kurtzhals, Jørgen, Addae, M. M., Akanmori, B. D., Dunyo, S., Koram, K. A., Appawu, M. A., Nkrumah, F. K. & Hviid, Lars, 1999, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 93, 6, p. 623-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The cytokine balance in severe malarial anemia
Kurtzhals, Jørgen, Akanmori, B. D., Goka, B. Q., Adabayeri, V., Nkrumah, F. K., Behr, C. & Hviid, Lars, 1999, In: Journal of Infectious Diseases. 180, 5, p. 1753-5 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Suitability of IgG responses to multiple Plasmodium falciparum antigens as markers of transmission intensity and pattern
Kyei-Baafour, E., Oppong, M., Kusi, K. A., Frempong, A. F., Aculley, B., Arthur, F. K. N., Tiendrebeogo, R. W., Singh, S. K., Theisen, Michael, Kweku, M., Adu, B., Hviid, Lars & Ofori, M. F., 2021, In: PLoS ONE. 16, 4, e0249936.Research output: Contribution to journal › Journal article › Research › peer-review
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Enzyme-linked immunosorbent assay for activation of the classical complement pathway by Plasmodium falciparum-infected erythrocyte surface antigen-specific antibodies
Larsen, M. D., Bayarri-Olmos, R., Garred, Peter & Hviid, Lars, 2022, In: Methods in Molecular Biology. 2470, p. 673-678 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination
Larsen, M. D., Lopez-Perez, Mary, Dickson, E. K., Ampomah, P., Tuikue Ndam, N., Nouta, J., Koeleman, C. A. M., Ederveen, A. L. H., Mordmüller, B., Salanti, Ali, Nielsen, Morten Agertoug, Massougbodji, A., van der Schoot, C. E., Ofori, M. F., Wuhrer, M., Hviid, Lars & Vidarsson, G., 2021, In: Nature Communications. 12, 5838.Research output: Contribution to journal › Journal article › Research › peer-review
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Malaria parasite evasion of classical complement pathway attack
Larsen, M. D., Ditlev, S., Olmos, R. B., Ampomah, P., Ofori, M. F., Garred, Peter & Hviid, Lars, 2017, In: Molecular Immunology. 89, p. 159-159Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Evasion of classical complement pathway activation on Plasmodium falciparum-infected erythrocytes opsonized by PfEMP1-specific IgG
Larsen, M. D., Quintana Varon, Maria del Pilar, Ditlev, S. B., Bayarri-Olmos, R., Ofori, M. F., Hviid, Lars & Garred, Peter, 2019, In: Frontiers in Immunology. 9, 3088.Research output: Contribution to journal › Journal article › Research › peer-review
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Expression of Plasmodium falciparum erythrocyte membrane protein 1 in experimentally infected humans
Lavstsen, Thomas, Magistrado, P., Hermsen, C. C., Salanti, Ali, Jensen, Anja Ramstedt, Sauerwein, R., Hviid, Lars, Theander, Thor Grundtvig & Staalsoe, T., 2005, In: Malaria Journal. 4, 1, p. 21Research output: Contribution to journal › Journal article › Research › peer-review
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Structure-guided identification of a family of dual receptor-binding PfEMP1 that is associated with cerebral malaria
Lennartz, F., Adams, Y., Bengtsson, A., Olsen, R. W., Turner, L., Ndam, N. T., Ecklu-Mensah, G. D., Moussiliou, A., Ofori, M. F., Gamain, B., Lusingu, J. P., Petersen, J. E. V., Wang, C. W., Nunes-Silva, S., Jespersen, J. S., Lau, C. K. Y., Theander, T. G., Lavstsen, T., Hviid, L., Higgins, M. K. & 1 others, , 8 Mar 2017, In: Cell Host & Microbe. 21, 3, p. 403-414 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Vß profiles in African children with acute cerebral or uncomplicated malaria: very focused changes among a remarkable global stability
Loizon, S., Boeuf, P., Tetteh, J. K. A., Goka, B., Obeng-Adjei, G., Kurtzhals, J. A. L., Rogier, C., Akanmori, B. D., Mercereau-Puijalon, O., Hviid, Lars & Behr, C., 2007, In: Microbes and Infection. 9, 11, p. 1252-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biomarker of Anopheles exposure in Ghanaian children with hemoglobin S and C
Londono-Renteria, B., Seidu, Zakaria, Lamptey, H., Ofori, M. F., Hviid, Lars & Lopez-Perez, Mary, 2024, In: Acta Tropica. 249, 8 p., 107043.Research output: Contribution to journal › Journal article › Research › peer-review
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PfEMP1-specific immunoglobulin G reactivity among Beninese pregnant women with sickle cell trait
Lopez-Perez, Mary, Viwami, F., Seidu, Zakaria, Jensen, Anja Ramstedt, Doritchamou, J., Ndam, N. T. & Hviid, Lars, 2021, In: Open Forum Infectious Diseases. 8, 12, ofab527.Research output: Contribution to journal › Journal article › Research › peer-review
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Binding of human serum proteins to Plasmodium falciparum-infected erythrocytes and its association with malaria clinical presentation
Lopez-Perez, Mary, van der Puije, W., Castberg, F. C., Ofori, M. F. & Hviid, Lars, 2020, In: Malaria Journal. 19, 1, 362.Research output: Contribution to journal › Journal article › Research › peer-review
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IgG responses to the Plasmodium falciparum antigen VAR2CSA in Colombia are restricted to pregnancy and are not induced by exposure to Plasmodium vivax
Lopez-Perez, Mary, Larsen, M. D., Bayarri-Olmos, R., Ampomah, P., Stevenson, L., Arévalo-Herrera, M., Herrera, S. & Hviid, Lars, 2018, In: Infection and Immunity. 86, 8, e00136-18.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural acquired immunity to malaria antigens among pregnant women with hemoglobin C trait
Lopez-Perez, Mary, Viwami, F., Doritchamou, J., Ndam, N. T. & Hviid, Lars, 2022, In: American Journal of Tropical Medicine and Hygiene. 106, 3, p. 853–856Research output: Contribution to journal › Journal article › Research › peer-review
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Levels of plasma immunoglobulin G with specificity against the cysteine-rich interdomain regions of a semiconserved Plasmodium falciparum erythrocyte membrane protein 1, VAR4, predict protection against malarial anemia and febrile episodes
Lusingu, J. P. A., Jensen, Anja Ramstedt, Vestergaard, L. S., Minja, D. T., Dalgaard, M. B., Gesase, S., Mmbando, B. P., Kitua, A. Y., Lemnge, M. M., Cavanagh, D., Hviid, Lars & Theander, Thor Grundtvig, 2006, In: Infection and Immunity. 74, 5, p. 2867-75 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 3620
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3588
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Kinetics of B Cell responses to Plasmodium falciparum erythrocyte membrane protein 1 in Ghanaian women naturally exposed to malaria parasites
Research output: Contribution to journal › Journal article › Research › peer-review
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2096
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Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites
Research output: Contribution to journal › Journal article › Research › peer-review
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2065
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B-cell responses to pregnancy-restricted and -unrestricted Plasmodium falciparum erythrocyte membrane protein 1 antigens in Ghanaian women naturally exposed to malaria parasites
Research output: Contribution to journal › Journal article › Research › peer-review
Published