Marco van de Weert
Associate Professor
Drug Delivery and Biophysics of Biopharmaceuticals
Universitetsparken 2
2100 København Ø
- Published
Correlation between enzyme activity an stability of a protease, an alpha-amaylase and a lipase in a simplified liquid laundry detergent system, determined by differential scanning calorimetry
Lund, H., Kaasgaard, S. G., Skagerlind, P., Jørgensen, Lene, Jørgensen, C. I. & van de Weert, Marco, 2012, In: Journal of Surfactants and Detergents. 15, p. 9-21Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protease and amylase stability in the presence of chelators used in laundry detergent applications: correlation between chelator properties and enzyme stability in liquid detergents
Lund, H., Kaasgaard, S. G., Skagerlind, P., Jørgensen, Lene, Jørgensen, C. I. & van de Weert, Marco, 2012, In: Journal of Surfactants and Detergents. 15, 3, p. 265-276Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design of experiments-based monitoring of critical quality attributes for the spray-drying process of insulin by NIR spectroscopy
Maltesen, M. J., van de Weert, Marco & Grohganz, Holger, 2012, In: A A P S PharmSciTech. 13, 3, p. 747-55 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of insulin allostery in solution and solid state with FTIR
Maltesen, M. J., Bjerregaard, S., Hovgaard, L., Havelund, S. & van de Weert, Marco, 2009, In: Journal of Pharmaceutical Sciences. 98, 9, p. 3265-3277Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quality by design: Spray drying of insulin intended for inhalation
Maltesen, M. J., Bjerregaard, S., Hovgaard, L., Havelund, S. & van de Weert, Marco, 2008, In: European Journal of Pharmaceutics and Biopharmaceutics. 70, 3, p. 828-838Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drying methods for protein pharmaceuticals
Maltesen, M. J. & van de Weert, Marco, 2008, In: Drug Discovery Today: Technologies. 5, 2-3, p. 81-88Research output: Contribution to journal › Review › Research › peer-review
- Published
Erratum to: Design of experiments-based monitoring of critical quality attributes for the spray-drying process of insulin by NIR spectroscopy
Maltesen, M. J., van de Weert, Marco & Grohganz, Holger, 21 Feb 2013, In: A A P S PharmSciTech. 14, 2, p. 901 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Multivariate analysis of phenol in freeze-dried and spray-dried insulin formulations by NIR and FTIR
Maltesen, M. J., Bjerregaard, S., Hovgaard, L., Havelund, S., van de Weert, Marco & Grohganz, Holger, 2011, In: A A P S PharmSciTech. 12, 2, p. 627-635Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Correlation between calculated molecular descriptors of excipient amino acids and experimentally observed thermal stability of lysozyme
Meng-Lund, H., Friis, N., van de Weert, Marco, Rantanen, Jukka, Poso, A., Grohganz, Holger & Jørgensen, Lene, 15 May 2017, In: International Journal of Pharmaceutics. 523, 1, p. 238-245 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stability of monoclonal antibodies at high-concentration: head-to-head comparison of the IgG1 and IgG4 subclass
Neergaard, M. S., Nielsen, A. D., Parshad, H. & van de Weert, Marco, Jan 2014, In: Journal of Pharmaceutical Sciences. 103, 1, p. 115-27 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Viscosity of high concentration protein formulations of monoclonal antibodies of the IgG1 and IgG4 subclass - Prediction of viscosity through protein-protein interaction measurements
Neergaard, M. S., Kalonia, D. S., Parshad, H., Nielsen, A., Møller, E. H., van de Weert, Marco & Nielsen, A. D., 26 Apr 2013, In: European Journal of Pharmaceutical Sciences. 49, 3, p. 400-410 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Influence of neutron irradiation on holmium acetylacetonate loaded poly(L-lactic acid) microspheres
Nijsen, J. F., van Het Schip, A. D., van Steenbergen, M. J., Zielhuis, S. W., Kroon-Batenburg, L. M. J., van de Weert, Marco, van Rijk, P. P. & Hennink, W. E., Apr 2002, In: Biomaterials. 23, 8, p. 1831-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Characterization of poly(L-lactic acid) microspheres loaded with holmium acetylacetonate
Nijsen, J. F. W., van Steenbergen, M. J., Kooijman, H., Talsma, H., Kroon-Batenburg, L. M. J., van de Weert, Marco, van Rijk, P. P., de Witte, A., van het Schip, A. D. & Hennink, W. E., 2001, In: Biomaterials. 22, p. 3073-3081Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The chaperone-like protein a-crystallin dissociates insulin dimers and hexamers
Rasmussen, T., Kasimova, M. R., Jiskoot, W. & van de Weert, Marco, 2009, In: Biochemistry. 48, p. 9313-9320Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thermal and acid denaturation of bovine lens a-crystallin
Rasmussen, T., van de Weert, Marco, Jiskoot, W. & Kasimova, M. R., 2011, In: Proteins - Structure Function and Bioinformatics. 79, 6, p. 1747-1758Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The molecular chaperone a-crystallin as an excipient in an insulin formulation
Rasmussen, T., Tantipolphan, R., van de Weert, Marco & Jiskoot, W., 2010, In: Pharmaceutical Research. 27, p. 1337-1347Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Engineering of a novel adjuvant based on lipid-polymer hybrid nanoparticles: A quality-by-design approach
Rose, F., Wern, J. E., Ingvarsson, P. T., van de Weert, Marco, Andersen, P., Follmann, F. & Foged, Camilla, 2015, In: Journal of controlled release : official journal of the Controlled Release Society. 210, p. 48-57 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probing insulin's secondary structure after entrapment into alginate/chitosan nanoparticles
Sarmento, B., Ferreira, D. C., Jørgensen, Lene & van de Weert, Marco, 2007, In: European Journal of Pharmaceutics and Biopharmaceutics. 65, 1, p. 10-17Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of statistical design/modeling for prediction of the effect of amino acids on agitation-induced aggregation of human growth hormone and human insulin
Soenderkaer, S., van de Weert, Marco, Lindgaard Hansen, L., Flink, J. & Frøkjær, Sven, 2005, In: Journal of Drug Delivery Science and Technology. 15, 6, p. 427-434 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of sucrose on rFVIIa aggregation and methionine oxidation
Soenderkaer, S., Carpenter, J. F., van de Weert, Marco, Hansen, L. L., Flink, J. & Frøkjær, Sven, Apr 2004, In: European Journal of Pharmaceutical Sciences. 21, 5, p. 597-606 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fluorescence spectroscopy and binding: Getting it right
Stella, L., van de Weert, Marco, Burrows, H. D. & Fausto, R., 5 Dec 2014, In: Journal of Molecular Structure: THEOCHEM. 1077, p. 1-3 3 p.Research output: Contribution to journal › Editorial › Research
- Published
Characterisation and physical stability of PEGylated glucagon
Stigsnæs, P., Frøkjær, Sven, Bjerregaard, S., van de Weert, Marco, Kingshott, P. & Møller, E. H., 2007, In: Internation Journal of Pharmaceutics. 330, 1-2, p. 89-98Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rhamnogalacturonan-I based microcapsules for targeted drug release
Svagan, A. J., Kusic, A., De Gobba, Cristian, Larsen, F. H., Sassene, P., Zhou, Q., van de Weert, Marco, Mullertz, Anette , Jørgensen, Bodil & Ulvskov, Peter, 2016, In: P L o S One. 11, 12, 13 p., e0168050.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies on human insulin adsorption kinetics at an organic-aqueous interface determined using a label-free electroanalytical approach
Thomsen, A. E., Jensen, H., Jørgensen, Lene, van de Weert, Marco & Østergaard, Jesper, 2008, In: Colloids and Surfaces B: Biointerfaces. 63, 2, p. 243-248Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fuzzy Logic-based expert system for evaluating cake quality of freeze-dried formulations
Trnka, H., Wu, J., van de Weert, Marco, Grohganz, Holger & Rantanen, Jukka, Dec 2013, In: Journal of Pharmaceutical Sciences. 102, 12, p. 4364-74 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Erratum: Fluorescence quenching to study protein-ligand binding: Common errors (Journal of Fluorescence (2010) 20 (625-629)DOI 10.1007/s10895-009-0572- x)
van de Weert, Marco, 29 Aug 2011, In: Journal of Fluorescence. 21, 6, 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Lysozyme distribution and conformation in a biodegradable polymer matrix as determined by FTIR techniques
van de Weert, Marco, Van 'T Hof, R., Van Der Weerd, J., Heeren, R. M. A., Posthuma, G., Hennink, W. E. & Crommelin, D. J. A., 31 Jul 2000, In: Journal of Controlled Release. 68, 1, p. 31-40 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preface
van de Weert, Marco & Møller, E. H., 2008, Immunogenicity of biopharmaceuticals. van de Weert, M. & Møller, E. H. (eds.). 1 ed. New York: Springer, p. v-viResearch output: Chapter in Book/Report/Conference proceeding › Preface/postscript › Research
- Published
Delivery technologies for biopharmaceuticals: a critical assessment
van de Weert, Marco, 2009, Delivery technologies for biopharmaceuticals: Peptides, proteins, nucleic acids and vaccines. Jørgensen, L. & Mørck Nielsen, H. (eds.). Chichester: Wiley, p. 407-411Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
Immunogenicity of biopharmaceuticals: methods to reduce immunogenicity and biosimilars
van de Weert, Marco & Møller, E. H., 2008, Immunogenicity of biopharmaceuticals. van de Weert, M. & Møller, E. H. (eds.). 1 ed. New York: Springer, p. 97-111Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
Fluorescence quenching to study protein-ligand binding: Common errors
van de Weert, Marco, 2010, In: Journal of Fluorescence. 20, p. 625-629Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein pharmaceuticals
van de Weert, Marco & Møller, E. H., 2008, In: Drug Discovery Today: Technologies. 5, 2-3, p. 35-36Research output: Contribution to journal › Editorial › Research
- Published
Large-scale biophysical evaluation of protein PEGylation effects: in vitro properties of 61 protein entities
Vernet, E., Popa, G., Pozdnyakova, I., Rasmussen, J. E., Grohganz, Holger, Giehm, L., Jensen, M. H., Wang, H., Plesner, B., Nielsen, Hanne Mørck, Jensen, Knud Jørgen, Berthelsen, J., Sundström, M. & van de Weert, Marco, 2016, In: Molecular Pharmaceutics. 13, 5, p. 1587-1598 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A helical structural nucleus is the primary elongating unit of insulin amyloid fibrils
Vestergaard, Bente, Jensen, M. G., Roessle, M., Kastrup, Jette Sandholm Jensen, van de Weert, Marco, Flink, J. M., Frøkjær, Sven, Gajhede, Michael & Svergun, D. I., 2007, In: PLoS - Biology. 5, 5, p. 1089-1097Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bioinformatic and experimental analysis of the secondary structure of amelogenin
Vilhjalmsson, B., Rasmussen, Anne, Fabi, B., van de Weert, Marco, Hamelryck, Thomas Wim & Lemoult, S., 1 Nov 2007, In: European Cells and Materials. 14, SUPPL.2, 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complex coacervates of hyaluronic acid and lysozyme: Effect on protein structure and physical stability
Water, J. J., Schack, M. M., Velazquez-Campoy, A., Maltesen, M. J., van de Weert, Marco & Jørgensen, Lene, 1 Jan 2014, In: European Journal of Pharmaceutics and Biopharmaceutics. 88, 2, p. 325-331 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serial Coupling of Ion-Exchange and Size-Exclusion Chromatography to Determine Aggregation Levels in mAbs in The Presence of a Proteinaceous Excipient, Recombinant Human Serum Albumin
Weisbjerg, P. L. G., Caspersen, M. B., Cook, K. & van de Weert, Marco, 1 Dec 2014, In: Journal of Pharmaceutical Sciences. 104, 2, p. 548-556 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of excipients on encapsulation and release of insulin from spray-dried solid lipid microparticles
Wu, C., van de Weert, Marco, Baldursdottir, S. G., Yang, Mingshi & Mu, Huiling, 25 Oct 2018, In: International Journal of Pharmaceutics. 550, 1-2, p. 439-446Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterisation of salmon calcitonin in spray-dried powder for inhalation. Effect of chitosan
Yang, Mingshi, Velaga, S., Yamamoto, H., Takeuchi, H., Kawashima, Y., Hovgaard, L., van de Weert, Marco & Frøkjær, Sven, 2007, In: Internation Journal of Pharmaceutics. 331, 2, p. 176-181Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Corrigendum to "Polysorbate 80 controls Morphology, structure and stability of human insulin Amyloid-Like spherulites" [J. Colloid Interface Sci. 606(Part 2) (2022) 1928-1939]
Zhou, X., Galparsoro, D. F., Madsen, Anders Østergaard, Vetri, V., van de Weert, Marco, Nielsen, Hanne Mørck & Foderà, Vito, 2023, In: Journal of Colloid and Interface Science. 640, p. 917Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heterogeneous and Surface-Catalyzed Amyloid Aggregation Monitored by Spatially Resolved Fluorescence and Single Molecule Microscopy
Zhou, X., Sinkjær, Anders Wilgaard, Zhang, Min, Pinholt, H. D., Nielsen, Hanne Mørck, Hatzakis, Nikos, van de Weert, Marco & Foderà, Vito, 2023, In: The Journal of Physical Chemistry Letters. 14, 4, p. 912-919Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polysorbate 80 Controls Morphology, Structure and Stability of Human Insulin Amyloid-Like Spherulites
Zhou, X., Galparsoro, D. F., Madsen, Anders Østergaard, Vetri, V., van de Weert, Marco, Nielsen, Hanne Mørck & Foderà, Vito, 10 Aug 2021, bioRxiv, 52 p.Research output: Working paper › Preprint › Research
- Published
Polysorbate 80 controls Morphology, structure and stability of human insulin Amyloid-Like spherulites
Zhou, X., Fennema Galparsoro, D., Madsen, Anders Østergaard, Vetri, V., van de Weert, Marco, Nielsen, Hanne Mørck & Foderà, Vito, 2022, In: Journal of Colloid and Interface Science. 606, Pt 2, p. 1928-1939Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of a cyclosporine solid dispersion for inhalation
Zijlstra, G. S., Rijkeboer, M., van Drooge, D. J., Sutter, M., Jiskoot, W., van de Weert, Marco, Hinrichs, W. L. J. & Frijlink, H. W., 2007, In: The AAPS journal. 9, 2, p. E190-E199Research output: Contribution to journal › Journal article › Research › peer-review
Stability aspects of salmon calcitonin entrapped in poly(ether-ester) sustained release systems
van Dijkhuizen-Radersma, R., Nicolas, H. M., van de Weert, Marco, Blom, M., de Groot, K. & Bezemer, J. M., 6 Nov 2002, In: International Journal of Pharmaceutics. 248, 1-2, p. 229-37 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fourier transform infrared spectroscopy of protein formulations
van de Weert, Marco, Hering, J. A. & Haris, P. I., 2005, Methods for Structural Analysis of Protein Pharmaceuticals. Jiskoot, W. & Crommelin, D. (eds.). Arlington: Springer Science+Business Media, p. 131-166Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
Semisolid, self-catalyzed poly(ortho ester)s as controlled-release systems: protein release and protein stability issues
van de Weert, Marco, van Steenbergen, M. J., Cleland, J. L., Heller, J., Hennink, W. E. & Crommelin, D. J. A., Apr 2002, In: Journal of Pharmaceutical Sciences. 91, 4, p. 1065-74 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Fourier transform infrared spectrometric analysis of protein conformation: effect of sampling method and stress factors
van de Weert, Marco, Haris, P. I., Hennink, W. E. & Crommelin, D. J., 15 Oct 2001, In: Analytical Biochemistry. 297, 2, p. 160-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physical Instability of Peptides and Proteins
van de Weert, Marco & Randolph, T. W., 2013, Pharmaceutical Formulation Development of Peptides and Proteins. Hovgaard, L., Frokjaer, S. & van de Weert, M. (eds.). 2 ed. Boca Raton: CRC Press, p. 107-130Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
Characterization of Therapeutic Peptides and Proteins
van de Weert, Marco & Arvinte, T., 2013, Pharmaceutical Formulation Development of Peptides and Proteins. Hovgaard, L., Frokjaer, S. & van de Weert, M. (eds.). 2 ed. Boca Raton: CRC Press, p. 49-78Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
ID: 1302800
Most downloads
-
459
downloads
Preferential interactions and the effect of protein PEGylation
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
431
downloads
On the purported "backbone fluorescence" in protein three-dimensional fluorescence spectra
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
293
downloads
Rhamnogalacturonan-I based microcapsules for targeted drug release
Research output: Contribution to journal › Journal article › Research › peer-review
Published